CN116322655A - 调节释放软凝胶胶囊 - Google Patents

调节释放软凝胶胶囊 Download PDF

Info

Publication number
CN116322655A
CN116322655A CN202180070928.5A CN202180070928A CN116322655A CN 116322655 A CN116322655 A CN 116322655A CN 202180070928 A CN202180070928 A CN 202180070928A CN 116322655 A CN116322655 A CN 116322655A
Authority
CN
China
Prior art keywords
modified release
soft gel
capsule according
composition
weight
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN202180070928.5A
Other languages
English (en)
Chinese (zh)
Inventor
K·苏库鲁
Q·方
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
RP Scherer Technologies LLC
Original Assignee
RP Scherer Technologies LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by RP Scherer Technologies LLC filed Critical RP Scherer Technologies LLC
Publication of CN116322655A publication Critical patent/CN116322655A/zh
Pending legal-status Critical Current

Links

Images

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4866—Organic macromolecular compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A61K31/167—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
    • A61K31/202—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids having three or more double bonds, e.g. linolenic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4816—Wall or shell material
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4816—Wall or shell material
    • A61K9/4825—Proteins, e.g. gelatin

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Inorganic Chemistry (AREA)
  • Pain & Pain Management (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Medicinal Preparation (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CN202180070928.5A 2020-10-16 2021-10-15 调节释放软凝胶胶囊 Pending CN116322655A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202063092762P 2020-10-16 2020-10-16
US63/092,762 2020-10-16
PCT/US2021/071900 WO2022082222A1 (en) 2020-10-16 2021-10-15 Modified release softgel capsules

Publications (1)

Publication Number Publication Date
CN116322655A true CN116322655A (zh) 2023-06-23

Family

ID=81208677

Family Applications (1)

Application Number Title Priority Date Filing Date
CN202180070928.5A Pending CN116322655A (zh) 2020-10-16 2021-10-15 调节释放软凝胶胶囊

Country Status (14)

Country Link
US (1) US20230390210A1 (https=)
EP (1) EP4228597A4 (https=)
JP (1) JP2023547062A (https=)
KR (1) KR20230088388A (https=)
CN (1) CN116322655A (https=)
AR (1) AR123805A1 (https=)
AU (1) AU2021362248A1 (https=)
BR (1) BR112023006154A2 (https=)
CA (1) CA3194160A1 (https=)
CO (1) CO2023005753A2 (https=)
IL (1) IL301715A (https=)
MX (1) MX2023004418A (https=)
TW (1) TW202228656A (https=)
WO (1) WO2022082222A1 (https=)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2025135085A1 (ja) * 2023-12-22 2025-06-26 花王株式会社 カプセル剤

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4708834A (en) * 1986-05-01 1987-11-24 Pharmacaps, Inc. Preparation of gelatin-encapsulated controlled release composition
CN1615126A (zh) * 2001-11-22 2005-05-11 森下仁丹株式会社 非胶凝状的胶囊膜组合物和使用其所形成的胶囊
US20160213611A1 (en) * 2013-02-21 2016-07-28 Sigmoid Pharma Limited Method for treating intestinal fibrosis
US20180271817A1 (en) * 2014-06-23 2018-09-27 Patheon Softgels Inc. All-natural enteric soft capsules

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7842307B2 (en) * 2001-08-06 2010-11-30 Purdue Pharma L.P. Pharmaceutical formulation containing opioid agonist, opioid antagonist and gelling agent
KR100575199B1 (ko) * 2003-01-24 2006-05-02 알앤피코리아주식회사 연질 캡슐의 블루밍 방지를 위한 가소제 조성물 및 이를함유한 피막
IT1401313B1 (it) * 2010-08-05 2013-07-18 Perfetti Van Melle Spa Caramelle gelatinose con ripieno fluido e metodo di ottenimento
US20120301546A1 (en) * 2011-05-26 2012-11-29 Hassan Emadeldin M Acid-resistant soft gel compositions
GB201319792D0 (en) * 2013-11-08 2013-12-25 Sigmoid Pharma Ltd Formulations
US20170119680A1 (en) * 2015-10-30 2017-05-04 R.P. Scherer Technologies, Llc Extended release film-coated capsules
US20210353574A1 (en) * 2018-10-16 2021-11-18 Bayer Healthcare Llc Softgels with solid or gel-like polymeric fill matrix
MX2022005050A (es) * 2019-10-28 2022-07-04 Scherer Technologies Llc R P Cápsulas de gelatina blanda de liberación retardada en entorno de ph más alto.

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4708834A (en) * 1986-05-01 1987-11-24 Pharmacaps, Inc. Preparation of gelatin-encapsulated controlled release composition
CN1615126A (zh) * 2001-11-22 2005-05-11 森下仁丹株式会社 非胶凝状的胶囊膜组合物和使用其所形成的胶囊
US20160213611A1 (en) * 2013-02-21 2016-07-28 Sigmoid Pharma Limited Method for treating intestinal fibrosis
US20180271817A1 (en) * 2014-06-23 2018-09-27 Patheon Softgels Inc. All-natural enteric soft capsules
US10357467B2 (en) * 2014-06-23 2019-07-23 Patheon Softgels, Inc. All-natural enteric soft capsules

Also Published As

Publication number Publication date
CO2023005753A2 (es) 2023-05-29
EP4228597A4 (en) 2024-10-02
AU2021362248A1 (en) 2023-06-01
MX2023004418A (es) 2023-05-04
TW202228656A (zh) 2022-08-01
US20230390210A1 (en) 2023-12-07
KR20230088388A (ko) 2023-06-19
CA3194160A1 (en) 2022-04-21
AR123805A1 (es) 2023-01-11
WO2022082222A1 (en) 2022-04-21
JP2023547062A (ja) 2023-11-09
BR112023006154A2 (pt) 2023-05-09
IL301715A (en) 2023-05-01
AU2021362248A9 (en) 2024-05-02
EP4228597A1 (en) 2023-08-23

Similar Documents

Publication Publication Date Title
JP6696994B2 (ja) 即放性乱用抑止性顆粒剤形
JP7558204B2 (ja) 遅延放出ソフトゲルカプセル
AU2020372884B2 (en) Delayed release softgel capsules in higher pH environment
EP3768094B1 (en) Enteric softgel capsules
CN116685311A (zh) 延迟释放软凝胶胶囊
CN116648238A (zh) 延迟释放软凝胶胶囊
JP2024059780A (ja) 腸溶性ソフトゲルカプセル剤
KR20220080130A (ko) 비-동물 소프트겔 캡슐 제제, 그의 제조 방법 및 사용 방법
CN116322655A (zh) 调节释放软凝胶胶囊
CN116528694A (zh) 延迟释放软凝胶胶囊
CN116367864A (zh) 控释填料组合物和含有该组合物的胶囊
HK40095991A (zh) 调节释放软凝胶胶囊
JP2025527319A (ja) コーティングされた腸溶性ソフトゲルカプセル剤
CN120282775A (zh) 软凝胶胶囊和制备软凝胶胶囊的方法
HK40090240A (zh) 控释填料组合物和含有该组合物的胶囊
HK40129573A (zh) 软凝胶胶囊和制备软凝胶胶囊的方法

Legal Events

Date Code Title Description
PB01 Publication
PB01 Publication
SE01 Entry into force of request for substantive examination
SE01 Entry into force of request for substantive examination
REG Reference to a national code

Ref country code: HK

Ref legal event code: DE

Ref document number: 40095991

Country of ref document: HK