MX2023004418A - Capsulas de gel blando de liberacion modificada. - Google Patents

Capsulas de gel blando de liberacion modificada.

Info

Publication number
MX2023004418A
MX2023004418A MX2023004418A MX2023004418A MX2023004418A MX 2023004418 A MX2023004418 A MX 2023004418A MX 2023004418 A MX2023004418 A MX 2023004418A MX 2023004418 A MX2023004418 A MX 2023004418A MX 2023004418 A MX2023004418 A MX 2023004418A
Authority
MX
Mexico
Prior art keywords
dependent
controlled release
modified release
softgel capsules
active agent
Prior art date
Application number
MX2023004418A
Other languages
English (en)
Inventor
Karunakar Sukuru
Qi Fang
Original Assignee
Scherer Technologies Llc R P
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Scherer Technologies Llc R P filed Critical Scherer Technologies Llc R P
Publication of MX2023004418A publication Critical patent/MX2023004418A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4816—Wall or shell material
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4866—Organic macromolecular compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A61K31/167—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
    • A61K31/202—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids having three or more double bonds, e.g. linolenic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4816—Wall or shell material
    • A61K9/4825—Proteins, e.g. gelatin

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Inorganic Chemistry (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Pain & Pain Management (AREA)
  • Medicinal Preparation (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Se describen cápsulas de gel blando de liberación modificada que incluyen una composición de cubierta dependiente de pH que encapsula una composición de relleno de liberación controlada, métodos de preparación de las mismas, y métodos de uso de las mismas. La composición de cubierta dependiente de pH puede caracterizarse en cuanto a que la naturaleza de liberación retardada de las cápsulas puede lograrse sin un recubrimiento dependiente de pH separado, ni polímeros dependientes de pH convencionales adicionados. Los geles blandos proveen una plataforma de liberación controlada dual que facilita el suministro del agente activo a una ubicación objetivo en el tracto gastrointestinal, y un perfil de liberación controlada del agente activo en la ubicación objetivo en el tracto gastrointestinal.
MX2023004418A 2020-10-16 2021-10-15 Capsulas de gel blando de liberacion modificada. MX2023004418A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US202063092762P 2020-10-16 2020-10-16
PCT/US2021/071900 WO2022082222A1 (en) 2020-10-16 2021-10-15 Modified release softgel capsules

Publications (1)

Publication Number Publication Date
MX2023004418A true MX2023004418A (es) 2023-05-04

Family

ID=81208677

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2023004418A MX2023004418A (es) 2020-10-16 2021-10-15 Capsulas de gel blando de liberacion modificada.

Country Status (14)

Country Link
US (1) US20230390210A1 (es)
EP (1) EP4228597A1 (es)
JP (1) JP2023547062A (es)
KR (1) KR20230088388A (es)
CN (1) CN116322655A (es)
AR (1) AR123805A1 (es)
AU (1) AU2021362248A1 (es)
BR (1) BR112023006154A2 (es)
CA (1) CA3194160A1 (es)
CO (1) CO2023005753A2 (es)
IL (1) IL301715A (es)
MX (1) MX2023004418A (es)
TW (1) TW202228656A (es)
WO (1) WO2022082222A1 (es)

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4708834A (en) * 1986-05-01 1987-11-24 Pharmacaps, Inc. Preparation of gelatin-encapsulated controlled release composition
GB201304662D0 (en) * 2013-03-14 2013-05-01 Sigmoid Pharma Ltd Compositions
GB201319792D0 (en) * 2013-11-08 2013-12-25 Sigmoid Pharma Ltd Formulations
CA2950311C (en) * 2014-06-23 2019-05-14 Banner Life Sciences Llc All natural enteric soft capsules comprising active ingredients
US20170119680A1 (en) * 2015-10-30 2017-05-04 R.P. Scherer Technologies, Llc Extended release film-coated capsules
EP3866758A1 (en) * 2018-10-16 2021-08-25 Bayer HealthCare LLC Softgels with solid or gel-like polymeric fill matrix
BR112022008064A2 (pt) * 2019-10-28 2022-07-12 Scherer Technologies Llc R P Cápsulas de softgel de liberação retardada em ambientes de ph mais alto

Also Published As

Publication number Publication date
BR112023006154A2 (pt) 2023-05-09
KR20230088388A (ko) 2023-06-19
WO2022082222A1 (en) 2022-04-21
TW202228656A (zh) 2022-08-01
IL301715A (en) 2023-05-01
EP4228597A1 (en) 2023-08-23
US20230390210A1 (en) 2023-12-07
AU2021362248A1 (en) 2023-06-01
CO2023005753A2 (es) 2023-05-29
AU2021362248A9 (en) 2024-05-02
AR123805A1 (es) 2023-01-11
JP2023547062A (ja) 2023-11-09
CN116322655A (zh) 2023-06-23
CA3194160A1 (en) 2022-04-21

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