CN116234906A - 血型抗原的修饰 - Google Patents

血型抗原的修饰 Download PDF

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Publication number
CN116234906A
CN116234906A CN202180022172.7A CN202180022172A CN116234906A CN 116234906 A CN116234906 A CN 116234906A CN 202180022172 A CN202180022172 A CN 202180022172A CN 116234906 A CN116234906 A CN 116234906A
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cell
gene
seq
guide rna
sequence
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Chinese (zh)
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W·道德勒
A·梅
S·施雷普费尔
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Sana Biotechnology Co ltd
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Sana Biotechnology Co ltd
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    • C12N15/90—Stable introduction of foreign DNA into chromosome
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    • C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
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    • C12Y204/01—Hexosyltransferases (2.4.1)
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    • C12N2800/00—Nucleic acids vectors
    • C12N2800/80—Vectors containing sites for inducing double-stranded breaks, e.g. meganuclease restriction sites

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CN202180022172.7A 2020-01-13 2021-01-12 血型抗原的修饰 Pending CN116234906A (zh)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US202062960607P 2020-01-13 2020-01-13
US202062960617P 2020-01-13 2020-01-13
US62/960,617 2020-01-13
US62/960,607 2020-01-13
PCT/US2021/013140 WO2021146222A1 (en) 2020-01-13 2021-01-12 Modification of blood type antigens

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Publication Number Publication Date
CN116234906A true CN116234906A (zh) 2023-06-06

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CN202180022172.7A Pending CN116234906A (zh) 2020-01-13 2021-01-12 血型抗原的修饰

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US (1) US20230272429A1 (enExample)
EP (1) EP4090743A1 (enExample)
JP (1) JP7853210B2 (enExample)
CN (1) CN116234906A (enExample)
AU (1) AU2021207810A1 (enExample)
CA (1) CA3164591A1 (enExample)
WO (1) WO2021146222A1 (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
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CN118638907A (zh) * 2024-06-26 2024-09-13 中国人民解放军联勤保障部队第九六〇医院 一种用于检测易漏检类孟买表型的snp标记

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US11162079B2 (en) 2019-05-10 2021-11-02 The Regents Of The University Of California Blood type O Rh-hypo-immunogenic pluripotent cells
CA3138597A1 (en) 2019-05-10 2020-11-19 The Regents Of The University Of California Modified pluripotent cells
IL308637A (en) * 2021-05-19 2024-01-01 Sana Biotechnology Inc Primary hypoimmunogenic T cells are RHD negative
AU2022325955A1 (en) 2021-08-11 2024-02-08 Sana Biotechnology, Inc. Genetically modified cells for allogeneic cell therapy to reduce instant blood mediated inflammatory reactions
JP2024534771A (ja) 2021-08-11 2024-09-26 サナ バイオテクノロジー，インコーポレイテッド 補体媒介性炎症反応を低減するための同種異系細胞療法のための遺伝子改変細胞
US20250129346A1 (en) * 2021-08-11 2025-04-24 Sana Biotechnology, Inc. Engineering cells for cell-based therapies, and associated compositions and methods
JP2024531234A (ja) 2021-08-11 2024-08-29 サナ バイオテクノロジー，インコーポレイテッド 同種異系細胞療法のための遺伝子改変された初代細胞
WO2023019226A1 (en) 2021-08-11 2023-02-16 Sana Biotechnology, Inc. Genetically modified cells for allogeneic cell therapy
WO2025117331A1 (en) 2023-12-01 2025-06-05 Eli Lilly And Company Methods of making stem cell-derived islet-like cells, as well as populations and compositions including the same
CN118291605A (zh) * 2024-04-10 2024-07-05 深圳市血液中心(深圳市输血医学研究所) 一种基于ngs的多系统红细胞血型基因分型方法和试剂盒
CN119913243A (zh) * 2025-04-01 2025-05-02 浙江省血液中心 Abo血型变异体的snp位点、b亚型变异型血型鉴定试剂盒和方法

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN118638907A (zh) * 2024-06-26 2024-09-13 中国人民解放军联勤保障部队第九六〇医院 一种用于检测易漏检类孟买表型的snp标记

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JP7853210B2 (ja) 2026-04-28
WO2021146222A1 (en) 2021-07-22
AU2021207810A1 (en) 2022-08-04
CA3164591A1 (en) 2021-07-22
EP4090743A1 (en) 2022-11-23
US20230272429A1 (en) 2023-08-31
JP2023510872A (ja) 2023-03-15

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