CN116211979B - 一种中药保胃散及其制备方法 - Google Patents
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Abstract
本申请提出了一种中药保胃散及其制备方法,涉及中药技术领域。其包括以下原料:金牛、救必应、海螵蛸、鸡骨香、白豆叩、台乌、黄芪、炒白术、鸡内金、春砂仁、木香、制元胡、川云连、制香附、田七以及生甘草。药材来源广泛,成本低,原料君臣使左,配伍合理,无副作用,针对胃部不适的各种症状,均有良好的治疗效果,值得推广。制备方法简单,无需复杂的提取工艺,将原料直接打成粉末,用热水冲服即可,没有复杂的工艺,却又很好的疗效。
Description
技术领域
本申请涉及中药技术领域,具体而言,涉及一种中药保胃散及其制备方法。
背景技术
慢性胃炎系指不同病因引起的各种慢性胃黏膜炎性病变,是一种常见病,其发病率在各种胃病中居首位。自纤维内镜广泛应用以来,对本病认识有明显提高。常见慢性浅表性胃炎、慢性糜烂性胃炎和慢性萎缩性胃炎。后者黏膜肠上皮化生,常累及贲门,伴有G细胞丧失和胃泌素分泌减少,也可累及胃体,伴有泌酸腺的丧失,导致胃酸,胃蛋白酶和内源性因子的减少。
慢性胃炎缺乏特异性症状,症状的轻重与胃黏膜的病变程度并非一致。大多数病人常无症状或有程度不同的消化不良症状如上腹隐痛、食欲减退、餐后饱胀、反酸等。慢性萎缩性胃炎患者可有贫血、消瘦、舌炎、腹泻等,个别病人伴黏膜糜烂者上腹痛较明显,并可有出血,如呕血、黑便。症状常常反复发作,无规律性腹痛,疼痛经常出现于进食过程中或餐后,多数位于上腹部、脐周、部分患者部位不固定,轻者间歇性隐痛或钝痛、严重者为剧烈绞痛。
目前市场上治疗慢性胃炎的药物大多效果单一、昂贵、副作用明显,所以急需要研究开发出一种疗效好、成本低、副作用小的治疗慢性胃炎的复方药剂。
发明内容
本申请的目的在于提供一种中药保胃散,针对胃部不适的各种症状,均有良好的治疗效果,药材来源广泛,成本低,原料君臣使左,配伍合理,无副作用,值得推广。
本申请的另一目的在于提供一种中药保胃散的制备方法,制备方法简单,无需复杂的提取工艺,将原料直接打成粉末,用热水冲服即可,没有复杂的工艺,却又很好的疗效。
为解决上述技术问题,本发明采用的技术方案为:
一方面,本申请实施例提供一种中药保胃散,包括以下原料:金牛、救必应、海螵蛸、鸡骨香、白豆叩、台乌、黄芪、炒白术、鸡内金、春砂仁、木香、制元胡、川云连、制香附、田七以及生甘草。
另一方面,本申请实施例提供一种中药保胃散的制备方法,其包括以下步骤:
步骤A:按比例称量以下原料:金牛、救必应、海螵蛸、鸡骨香、白豆叩、台乌、黄芪、炒白术、鸡内金、春砂仁、木香、制元胡、川云连、制香附、田七、白芨以及生甘草,采用巴氏消毒将原料消毒,备用;
步骤B:用球磨机打磨成粉末,将粉末分装成小包装,即得中药保胃散。
相对于现有技术,本申请的实施例至少具有如下优点或有益效果:
本申请实施例提供一种中药保胃散,针对胃部不适的各种症状,均有良好的治疗效果,药材来源广泛,成本低,原料君臣使左,配伍合理,无副作用,值得推广。
本申请实施例提供一种中药保胃散的制备方法,制备方法简单,无需复杂的提取工艺,将原料直接打成粉末,用热水冲服即可,没有复杂的工艺,却又很好的疗效。
具体实施方式
为使本申请实施例的目的、技术方案和优点更加清楚,下面将对本申请实施例中的技术方案进行清楚、完整地描述。实施例中未注明具体条件者,按照常规条件或制造商建议的条件进行。所用试剂或仪器未注明生产厂商者,均为可以通过市售购买获得的常规产品。
需要说明的是,在不冲突的情况下,本申请中的实施例及实施例中的特征可以相互组合。下面将参考具体实施例来详细说明本申请。
本申请实施例提供一种中药保胃散,包括以下原料:金牛、救必应、海螵蛸、鸡骨香、白豆叩、台乌、黄芪、炒白术、鸡内金、春砂仁、木香、制元胡、川云连、制香附、田七以及生甘草。
金牛的功效和作用包括:抗菌消炎,金牛富含生物碱,可以有效防止炎症的发生,同时可以提高抗炎能力;止痛,金牛可以降低疼痛的敏感度;能够提高身体的免疫力。
救必应,性味苦,寒,功能主治为清热解毒,利湿,止痛。治感冒发热,扁桃体炎,咽喉肿痛,急慢性肝炎,急性肠胃炎,胃及十二指肠溃疡,风湿关节痛,跌打损伤,汤火伤。
海螵蛸,味咸、涩、温,归脾、肾经。海螵蛸质燥涩敛,咸能走血,性温和血,入肝、脾、肾经。功长收涩,尤善止血止带,治崩漏带下效佳,堪称妇科之良药。此外,内服又善制酸止痛,外用又能收湿敛疮。现代研究显示,海螵蛸中主要含碳酸钙,含量约为80%。具有收敛止血,涩精止带,制酸止痛,收湿敛疮的功效。
鸡骨香,药性甘、微苦,凉。归肝、胃经。本品主要含相思子碱、相思子皂苷、黄酮类、氨基酸、糖类、相思子皂醇、甘草次酸。具有利湿退黄、清热解毒、疏肝止痛的功效。
白豆叩,味辛、性温,归肺、脾、胃经,功效化湿,行气,温中,止呕,主治化湿行气;温中止呕;开胃消食。主湿阻气滞;脾胃不和;脘腹胀满;不思饮食;湿温初起;胸闷不饥;胃寒呕吐;食积不消。
黄芪,黄芪药性甘,微温,归脾、肺经。黄芪甘温补升,甘淡渗利;生用微温,蜜炙性温,入脾、肺经,以扶正气,兼能除水邪。既善补中气、生举清阳,又善补肺气、益胃固表,治脾肺气虚、中气下陷、气不摄血、自汗盗汗等,还能托疮毒、利水消肿,治气血不足之疮痈不溃或久溃不敛、以及气虚水肿、小便不利。此外,通过补气又能生血、摄血、生津、行滞,治血虚菱黄、气不摄血之崩漏便血、气津两伤之消渴、气虚血滞之痹痛麻木和半身不遂等。
炒白术,具有健脾益气,燥湿利水,止汗,安胎的功效。用于脾虚食少,腹胀泄泻,痰饮眩悸,水肿,自汗,胎动不安。《医学启源》记载:“除湿益燥,和中益气,温中,去脾胃中湿,除胃热,强脾胃,进饮食,止渴,安胎。”
鸡内金,鸡内金味甘、平,归脾、胃、小肠、膀胱经。鸡内金甘益中,平不偏,消磨敛涩,药力较强。入脾、胃经,善运脾健胃、消食化积,为消食运脾之要药。入小肠、膀胱经,既化坚消食,又固精止遗,治结石、遗尿、遗精可选。中药材鸡内金主要含有胃液素(胃激素)、角蛋白、蛋白酶、淀粉酶、多种维生素、赖氨酸、丝氨酸等18种氨基酸及铝、钙、铬、钴、铜、铁等微元素。具有健胃消食,涩精止遗,通淋化石之功效。
春砂仁,味辛,性温,可调理胃肠功能,抑制胃酸,排除积气,常用于治疗腹胀、胸脘闷胀、食欲不香、恶心、呕吐等病症。
木香,性味辛、苦,温。归脾、胃、大肠、三焦、胆经。木香辛香温通,苦燥而降,可升可降。主入脾、胃经与大肠经,兼入三焦经与胆经。生用专于行散,能理气调中而止痛,消食、开胃、健脾。煨用行中有止,能实肠止泻。通理三焦,尤善行胃肠气滞,兼健脾消食,为行气调中止痛之要药,肠胃气滞有寒或兼食积、湿滞者用之最宜。本品含有挥发油,还含有种类众多的烯类成分,少量的酮、醛、酚等化合物。还含天冬氨酸、谷氨酸、γ-氨基丁酸等20种氨基酸,以及胆胺,木香萜胺A、B、C、D、E,豆甾醇,木香碱,树脂等。具有行气止痛,健脾消食的功效。
制香附,味辛、微苦、甘,性平。功效为疏肝理气,调经止痛。其主要成分有挥发油、β-蒎烯、莰烯。主治肝气郁滞,胸闷胁痛,胃病,腹痛。
田七,性味甘、微苦,温。归肝、胃经。具有化瘀止血,活血定痛的功效。主治出血症,跌打损伤,瘀血肿痛。
生甘草,甘草药性甘、平,归心、肺、脾、胃经。甘草甘补润缓,生平偏凉,平偏温,主入脾、肺经,兼入胃、心经。既益气补中,又缓急止痛、缓和药性,还祛痰止咳、解毒。炙补气缓急力强;生用能泻火解毒。
在本申请的一些实施例中,中药保胃散按重量分数计包括以下原料:金牛5-20份、救必应20-30份、海螵蛸20-30份、鸡骨香10-30份、白豆叩10-20份、台乌10-20份、黄芪20-30份、炒白术15-30份、鸡内金20-30份、春砂仁10-20份、木香10-20份、制元胡10-20份、川云连10-20份、制香附10-20份、田七10-20份以及生甘草5-20份。
在本申请的一些实施例中,中药保胃散按重量分数计包括以下原料:金牛10份、救必应20份、海螵蛸20份、鸡骨香10份、白豆叩10份、台乌10份、黄芪25份、炒白术20份、鸡内金20份、春砂仁10份、木香10份、制元胡10份、川云连10份、制香附10份、田七10份以及生甘草10份。
在本申请的一些实施例中,鸡内金为炒鸡内金。
炒鸡内金,是家鸡干沙袋的内壁,味甘,性平,归脾、胃、小肠和膀胱经,具有健胃消食、止血的功效。能缓解脾胃虚弱,提高脾胃功效,预防和缓解脾虚腹泻、恶心呕吐等不良症状。炒鸡内金性质温和,能清热解毒、消肿,在正常情况下,多吃炒鸡内金也可以有效减少体内毒素的积累;炒鸡内金是预防结石病的良药,能加速胆固醇在体内的分解和代谢,促进胆汁酸的分泌,防止胆固醇在人体内积聚,并从根本上减少结石的形成。
在本申请的一些实施例中,中药保胃散按重量分数计还包括白芨10-20份。
白芨,甘涩质黏,苦寒清泄,入肺、肝、胃经。善收敛止血,兼益肺胃,治体内外出血,最宜肺胃损伤之咳血、吐血,以及肺痈咳吐脓血。善消肿生肌,治痈疽疮疡,初起未脓服之可消,溃久不敛敷之可愈;治烫伤、皮肤皲裂、虹裂,外用能促进创口愈合。
本申请实施例提供一种中药保胃散的制备方法,其包括以下步骤:
步骤A:按比例称量以下原料:金牛、救必应、海螵蛸、鸡骨香、白豆叩、台乌、黄芪、炒白术、鸡内金、春砂仁、木香、制元胡、川云连、制香附、田七、白芨以及生甘草,采用巴氏消毒将原料消毒,备用;
步骤B:用球磨机打磨成粉末,将粉末分装成小包装,即得中药保胃散。
在本申请的一些实施例中,粉末的粒径为150-200目。粒径较小的粉末便于患者直接应热水冲服,更好溶解。
在本申请的一些实施例中,小包装的规格为:1.5-2.0g/袋。分装成小袋,刚好为1次服用的量,不但方便携带,而且方便患者在服用是能够更好的控制量,避免取药的时候污染其它的药,更加安全卫生。
以下结合实施例对本申请的特征和性能作进一步的详细描述。
实施例1
本申请实施例提供一种中药保胃散,具有制备方法包括以下步骤:
步骤A:按比例称量以下原料:金牛10g、救必应20g、海螵蛸20g、鸡骨香10g、白豆叩10g、台乌10g、黄芪20g、炒白术15g、炒鸡内金20g、春砂仁10g、木香10g、制元胡10g、川云连10g、制香附10g、田七10g以及生甘草10g,采用巴氏消毒将原料消毒,备用;
步骤B:用球磨机打磨成粒径为150目粉末,将粉末分装成规格为1.5g/袋的小包装,即得中药保胃散。
实施例2
本申请实施例提供一种中药保胃散,具有制备方法包括以下步骤:
步骤A:按比例称量以下原料:金牛20g、救必应30g、海螵蛸30g、鸡骨香20g、白豆叩20g、台乌20g、黄芪30g、炒白术20g、炒鸡内金30g、春砂仁20g、木香20g、制元胡20g、川云连20g、制香附20g、田七20g以及生甘草20g,采用巴氏消毒将原料消毒,备用;
步骤B:用球磨机打磨成粒径为200目粉末,将粉末分装成规格为2.0g/袋的小包装,即得中药保胃散。
实施例3
本申请实施例提供一种中药保胃散,具有制备方法包括以下步骤:
步骤A:按比例称量以下原料:金牛100g、救必应200g、海螵蛸200g、鸡骨香100g、白豆叩100g、台乌100g、黄芪250g、炒白术200g、炒鸡内金200g、春砂仁100g、木香100g、制元胡100g、川云连100g、制香附100g、田七100g以及生甘草100g,采用巴氏消毒将原料消毒,备用;
步骤B:用球磨机打磨成粒径为160目粉末,将粉末分装成规格为1.6g/袋的小包装,即得中药保胃散。
实施例4
本申请实施例提供一种中药保胃散,具有制备方法包括以下步骤:
步骤A:按比例称量以下原料:金牛10g、救必应20g、海螵蛸20g、鸡骨香10g、白豆叩10g、台乌10g、黄芪20g、炒白术15g、炒鸡内金20g、春砂仁10g、木香10g、制元胡10g、川云连10g、制香附10g、田七10g、白芨10g以及生甘草10g,采用巴氏消毒将原料消毒,备用;
步骤B:用球磨机打磨成粒径为170目粉末,将粉末分装成规格为1.7g/袋的小包装,即得中药保胃散。
实施例5
本申请实施例提供一种中药保胃散,具有制备方法包括以下步骤:
步骤A:按比例称量以下原料:金牛20g、救必应30g、海螵蛸30g、鸡骨香20g、白豆叩20g、台乌20g、黄芪30g、炒白术20g、炒鸡内金30g、春砂仁20g、木香20g、制元胡20g、川云连20g、制香附20g、田七20g、白芨20g以及生甘草20g,采用巴氏消毒将原料消毒,备用;
步骤B:用球磨机打磨成粒径为180目粉末,将粉末分装成规格为1.8g/袋的小包装,即得中药保胃散。
实施例6
本申请实施例提供一种中药保胃散,具有制备方法包括以下步骤:
步骤A:按比例称量以下原料:金牛100g、救必应200g、海螵蛸200g、鸡骨香100g、白豆叩100g、台乌100g、黄芪250g、炒白术200g、炒鸡内金200g、春砂仁100g、木香100g、制元胡100g、川云连100g、制香附100g、田七100g、白芨100g以及生甘草100g,采用巴氏消毒将原料消毒,备用;
步骤B:用球磨机打磨成粒径为190目粉末,将粉末分装成规格为1.9g/袋的小包装,即得中药保胃散。
实验例
邀请300位患有慢性胃炎的患者,分为6个治疗组,每个治疗组包括25名女生和25名男生,分别服用实施例1-实施例6所制备的中药保胃散,用开水冲服一小袋空腹服用,早晚各一次,服用两周后再做诊断,吃药期间禁忌:酒,酸菜,辣,冷冻。
诊断标准:
①幽门螺杆菌检查:可通过快速尿素酶试验、组织染色、细菌培养、血清抗HP抗体、13C-尿素呼气试验、粪便HP菌体抗原酶免法检测等方法检查HP阳性或阴性。
②X线钡餐检查:对慢性胃炎的诊断帮助不大,但有助于鉴别诊断。
③B超、CT不能诊断慢性胃炎。
④慢性胃炎的临床表现有:消化不良、上腹部痛、餐后饱胀、食欲减退、嗳气、反酸、恶心、呕吐等。
⑤缺乏特异性症状
疗效标准:
疗效判断标准(参照1984年11月中国中西医结合学会消化系统疾病专业委员会制定的疗效判断标准)
治愈:临床主要症状如胃脘冷痛、嗳气、胃脘胀满、倦怠乏力、食少便塘、脉沉细或迟、舌质淡嫩、苔薄白、舌边有齿痕等症均消失,胃镜检查,活动性炎症消失,慢性炎症好转,病理检查证实胃镜所见腺体萎缩恢复正常或消失。
显效:临床主要症状部份消失,胃镜复查粘膜急性炎症基本消失,慢性炎症好转,病理检查证实胃镜所见腺体萎缩,肠化或不典型增生减轻。
有效:临床主要症状明显减轻,胃镜复查粘膜病变范围缩小1/2以上,炎症有所减轻,病理检查证实胃镜所见急性炎症减炎,腺体萎缩,肠化或不典型增生减轻。
无效:达不到有效标准之病例而有恶化者。
对300位患者,服药两周后,做临床诊断的结果如表1所示:
表1.临床诊断结果
组别 | 治愈 | 显效 | 有效 | 无效 | 总有效性 |
实施例1 | 43 | 4 | 2 | 1 | 98% |
实施例2 | 44 | 4 | 2 | 0 | 100% |
实施例3 | 45 | 2 | 2 | 1 | 98% |
实施例4 | 43 | 4 | 2 | 1 | 98% |
实施例5 | 46 | 1 | 3 | 0 | 100% |
实施例6 | 45 | 4 | 1 | 0 | 100% |
由表1可知,300名志愿者在服用实施例1-实施例6的中药保胃散,总有效率高达98%,具有良好的治疗效果,对于胃部不适的各种症状,均有良好的治疗效果,对于慢性胃炎疗效确切,见效快,治愈率高、无毒副作用等优点。
综上所述,本申请实施例提供一种中药保胃散,针对胃部不适的各种症状,均有良好的治疗效果,药材来源广泛,成本低,原料君臣使左,配伍合理,无副作用,值得推广。
本申请实施例提供一种中药保胃散的制备方法,制备方法简单,无需复杂的提取工艺,将原料直接打成粉末,用热水冲服即可,没有复杂的工艺,却又很好的疗效。
以上所描述的实施例是本申请一部分实施例,而不是全部的实施例。本申请的实施例的详细描述并非旨在限制要求保护的本申请的范围,而是仅仅表示本申请的选定实施例。基于本申请中的实施例,本领域普通技术人员在没有作出创造性劳动前提下所获得的所有其他实施例,都属于本申请保护的范围。
Claims (6)
1.一种中药保胃散,其特征在于,按重量分数计,由以下原料制成:金牛5-20份、救必应20-30份、海螵蛸20-30份、鸡骨香10-30份、白豆叩10-20份、台乌10-20份、黄芪20-30份、炒白术15-30份、鸡内金20-30份、春砂仁10-20份、木香10-20份、制元胡10-20份、川云连10-20份、制香附10-20份、田七10-20份、生甘草5-20份以及白芨10-20份。
2.根据权利要求1所述的一种中药保胃散,其特征在于,按重量分数计,由以下原料制成:金牛10份、救必应20份、海螵蛸20份、鸡骨香10份、白豆叩10份、台乌10份、黄芪25份、炒白术20份、鸡内金20份、春砂仁10份、木香10份、制元胡10份、川云连10份、制香附10份、田七10份、生甘草10份以及白芨10份。
3.根据权利要求1所述的一种中药保胃散,其特征在于,所述鸡内金为炒鸡内金。
4.一种如权利要求1-3任一项所述的中药保胃散的制备方法,其特征在于,其包括以下步骤:
步骤A:按比例称量以下原料:金牛、救必应、海螵蛸、鸡骨香、白豆叩、台乌、黄芪、炒白术、鸡内金、春砂仁、木香、制元胡、川云连、制香附、田七、白芨以及生甘草,采用巴氏消毒将原料消毒,备用;
步骤B:将上述所有原料混合并用球磨机打磨成粉末,将粉末分装成小包装,即得中药保胃散。
5.根据权利要求4所述的中药保胃散的制备方法,其特征在于,所述粉末的粒径为150-200目。
6. 根据权利要求4所述的中药保胃散的制备方法,其特征在于,所述小包装的规格为:1 .5-2 .0g/袋。
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