CN116210708A - Nematicidal composition and application thereof - Google Patents

Nematicidal composition and application thereof Download PDF

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Publication number
CN116210708A
CN116210708A CN202211422511.3A CN202211422511A CN116210708A CN 116210708 A CN116210708 A CN 116210708A CN 202211422511 A CN202211422511 A CN 202211422511A CN 116210708 A CN116210708 A CN 116210708A
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nematodes
active ingredient
composition
formula
root
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葛尧伦
刘桂娟
杨志鹏
刘金玲
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Qingdao Hailier Biotechnology Co ltd
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    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/90—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having two or more relevant hetero rings, condensed among themselves or with a common carbocyclic ring system
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/34—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one nitrogen atom as the only ring hetero atom
    • A01N43/40—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one nitrogen atom as the only ring hetero atom six-membered rings
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/72—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with nitrogen atoms and oxygen or sulfur atoms as ring hetero atoms
    • A01N43/80—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with nitrogen atoms and oxygen or sulfur atoms as ring hetero atoms five-membered rings with one nitrogen atom and either one oxygen atom or one sulfur atom in positions 1,2
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

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  • Life Sciences & Earth Sciences (AREA)
  • Agronomy & Crop Science (AREA)
  • Pest Control & Pesticides (AREA)
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  • Wood Science & Technology (AREA)
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Abstract

The invention discloses a nematicidal composition and application thereof, wherein the composition contains an active ingredient A and an active ingredient B, the weight ratio of the active ingredient A to the active ingredient B is 1:50-50:1, and the A is a compound shown in a formula I; the active component B is any one of emamectin benzoate and lineaothiazole. The nematicidal composition is used for preventing plant parasitic nematodes, has good nematicidal activity, and has low toxicity to people and animals.

Description

Nematicidal composition and application thereof
Technical Field
The invention belongs to the technical field of pesticide nematicide compositions, and particularly relates to a nematicide composition and application thereof.
Background
With the continuous rise of the reseeding index of various places in China, nematode disease has become one of the main diseases of various crops. Plant parasitic nematodes are of up to 200 genera, involving more than 5000 species, where the major plant parasitic nematodes that jeopardize agriculture and forestry production include root-knot nematodes (Meloidogyne), cyst nematodes (hetodera), aphelenchida (Aphelenchina), stem nematodes (Ditylenchus), root-knot nematodes (Nacoblus) and root-knot nematodes (Pratelenchus), pine nematodes (Bursa phelenchus xylophilus), and the like.
The emamectin benzoate, namely emamectin benzoate (Emamectin benzoate), is a novel efficient semisynthetic antibiotic pesticide synthesized from a fermentation product avermectin B1, and can effectively prevent and treat pests such as lepidoptera, homoptera, coleoptera and various nematodes on vegetables, fruit trees and the like from damaging crops. The emamectin benzoate has the action mechanism of enhancing the actions of neurotransmitters such as glutamate and aminobutyric acid (GABA), so that the gamma-aminobutyric acid (GABA) enters nerve cells, is shown as an agonizing action on GABA, enables nerve endings to release GABA in a large amount, can promote GABA to generate long-time and high-strength combination with secondary neuron cell membranes or effector cell membranes, causes a large amount of chloride ions to enter the nerve cells, disturbs nerve conduction, and has the function of cells to lose, and larvae stop feeding soon after contacting with the medicament, so that irreversible paralysis occurs, meanwhile, the larvae can permeate to epidermis of target crops through Translaminar movement transfer due to tight and non-leaching combination with soil and do not accumulate in the environment, so that the pharmacodynamic period is prolonged.
Nematicidal thiazoles (benclothiaz) belong to the class of benzothiazole nematicides; CAS accession number: 89583-90-4, the English chemical name of which is 7-chloro-1, 2-benzothiazole. The compound of the formula I is a novel nematicide developed by Zhengda company, can paralyze nematode larvae and inhibit ova, and can be directly applied or seed treated to effectively control nematodes such as root knots, beet cysts, corn short bodies and the like on crops such as cucumber, tomato, corn, beet and the like. Chemical formula C 17 H 13 Cl 2 F 3 N 2 O, relative molecular mass 389.20, has the chemical structural formula:
Figure BDA0003942822480000011
the nematode control method includes agricultural control, physical control, chemical control, biological control and the like. As chemical pesticides have quick effect, nematode disease is mainly chemically controlled in actual production, but single or high-toxicity chemical wire killers are used for a long time, the problems of enhanced disease resistance, increased dosage year by year, unbalanced soil microorganisms, increased pesticide residues and the like are already caused in crop planting.
The biological activity of the compound on the target and the combination of different varieties are determined, so that the compound is one of effective methods for developing pesticides, improving the control effect and delaying the nematode resistance. The inventor has conducted intensive researches on the compound of the formula I, emamectin benzoate, nematicidal thiazole and combinations thereof, and found that the compound of the formula I, emamectin benzoate and nematicidal thiazole have better activity on root-knot nematodes, meanwhile, the compound of the formula I is mixed with any one of the emamectin benzoate and the nematicidal thiazole, and has obvious synergism on the nematodes in a certain mixing proportion range, so that the nematode control effect can be effectively improved, and the invention is completed through further researches. The compound of the formula I is mixed with any one of emamectin benzoate and lineazol for preventing and controlling plant parasitic nematodes, which is not reported at present.
Disclosure of Invention
The invention aims to provide a pesticide composition with higher activity on nematodes, which improves the actual control effect and effectively delays the occurrence of drug resistance of the nematodes.
The invention aims to achieve the aim, and the aim is achieved by the following technical scheme: a nematicidal composition comprises an active ingredient A and an active ingredient B, wherein the mass ratio of the active ingredient A to the active ingredient B is 1:50-50:1;
the active component A is a compound of formula I
Figure BDA0003942822480000021
The active component B is any one of emamectin benzoate and lineaothiazole;
further, the weight ratio of the active ingredient A to the active ingredient B is 1:32-45:1;
further, the weight ratio of the active ingredient A to the active ingredient B is 1:50, 1:32, 1:30, 1:16, 1:10, 1:7, 1:6, 5:2, 5:3, 1:1, 6:1, 8:1, 10:1, 15:1, 25:1, 45:1;
further, the mass ratio of the compound of the formula I to the emamectin benzoate is 1:7-15:1;
further, the mass ratio of the compound of the formula I to the emamectin benzoate is 1:7-10:1;
further, the mass ratio of the compound of the formula I to the lineazol is 1:30-15:1;
further, the mass ratio of the compound of the formula I to the lineazol is 1:10-8:1;
further, the sum of the weight of the active ingredient A and the weight of the active ingredient B accounts for 0.1% -90% of the composition;
further, the sum of the weight of the active ingredient A and the weight of the active ingredient B accounts for 1% -50% of the composition;
further, the sum of the weight of the active ingredient A and the weight of the active ingredient B accounts for 1% -20% of the composition;
further, the composition comprises an active ingredient and agricultural allowable pesticide auxiliary ingredients;
further, the pesticide auxiliary component of the composition is one or more selected from wetting agents, dispersing agents, emulsifying agents, thickening agents, disintegrating agents, antifreezing agents, antifoaming agents, solvents, preservatives, stabilizers, synergists and carriers;
further, the composition can be prepared into agriculturally acceptable dosage forms, including granules, emulsifiable concentrates and soluble solutions.
Use of a nematicidal composition to kill plant parasitic nematodes, said nematodes being any one or more of root knot nematodes (Meloidogyne), cyst nematodes (Heterodera), aphelenchus xylophilus (Aphelenchina), stem nematodes (Ditylenchus), root knot nematodes (Nacoblus) and root rot nematodes (Pratenenchus), pine wood nematodes (Bursa phelenchus xylophilus);
further, the nematodes are cyst nematodes and root-knot nematodes;
still further, the cyst nematode is a cyst Gu Bao nematode; the root-knot nematode is southern root-knot nematode [ Meloidogyne incongnita (Kofold & White) Chitwood ];
root-knot nematodes (Meloidogyne spp.) belong to the soil-dwelling endoparasitic nematodes, belonging to the phylum Meloidogyne (Secernentea) phylum, the phylum allelopathy (tyrenchida) heterodermally (heteoderidea) root-knot nematodes (Meloidogyne Goeldi) of the family Meloidogyne (Meloidogyne) have become one of the important pathogenic organisms that endanger crops. At present, the most serious pathogenic nematodes in the production of facility vegetables in China are southern root-knot nematodes [ Meloidogyne incongnita (Kofold & White) Chitwood ], which have the advantages of high propagation speed, strong resistance and easy propagation, and are also the main objects for current prevention and treatment. Root knot nematode disease is one of the main soil-borne diseases of facility vegetables, a large number of root knots are generated at the root of the vegetables parasitized by the root knot nematode, the normal physiological functions of the root are destroyed, the root rot can be caused when serious, and meanwhile, the overground part is short, dysplasia and yield are reduced; the wound when the root knot nematode invades is favorable for the invasion of other pathogenic matters of soil to form a compound disease, the root system of a plant invaded by 2 years old can generate a wound, and harmful pathogenic bacteria in the soil can invade into the plant body from the wound while the plant is still in motion, so that bacterial wilt, fusarium wilt, damping-off, root rot and other soil-borne diseases are generated and damaged, and secondary damage is caused to facility vegetables.
Cereal cyst nematodes (Cereal cyst nematode, CCN, heterodera avenae Wollenweber 1924) are an important class of infectious pathogenic nematodes, belonging to the phylum (tyrenchida) phylum (tyrenchina) heterodermaceae (heteoderidae) genus (heteodora), mainly infecting the roots of cereal crops and rapidly multiplying, causing the crop roots to become globular tumors, thereby impeding and inhibiting the growth of the crops, affecting the crop yield.
Further, the plant comprises: cucumber, tomato, peanut, tobacco, sweet potato, ginger, rice, towel gourd, balsam pear, watermelon, soybean, banana, pepper, sugarcane, strawberry, potato, citrus, kiwi, wheat, kenaf, celery. Wherein, because the humidity is big in the facility, soil structure is single, and continuous cropping cultivation mode leads to the root knot nematode of facility vegetables to attack seriously, the facility vegetables include: cucumber, tomato, luffa, balsam pear, celery, etc.
Compared with the prior art, the invention has the following advantages:
1) The composition has good nematicidal activity;
2) The pesticide has low toxicity, less residue in crops and little harm to human and livestock, well solves the problems of high toxicity and more residue in the crops of the existing nematicide, and improves the safety of agricultural production;
3) The composition is a mixture of compounds with different action mechanisms, can delay the generation of drug resistance of nematodes, lighten environmental pressure and prolong the service life of the compounds.
Detailed Description
For a better understanding of the nature of the present invention, reference will now be made in detail to the following examples, which are not intended to limit the invention, but are to be construed as limiting the scope of the invention.
Indoor activity
Example 1
Nematode collection method (preparation of nematode suspension)
Root knot nematode: several tomato root nodules are taken in the field, white egg blocks are picked under binoculars, and are placed in a hatching sieve for hatching at 25 ℃ to prepare nematode suspension for standby (the suspension liquid of 1mL contains no less than 100 second-instar larva nematodes).
Cyst nematode: taking soil from a wheat field to a laboratory, twisting the soil, uniformly mixing, washing the soil by a tap, stirring, sieving (100 meshes) and centrifuging, placing cysts in a 100-mesh sieve into a hatching sieve, soaking in sterile water, treating at a low temperature of 4 ℃ for 8 weeks, transferring to 16 ℃ for hatching, and starting from the second generation hatching of nematodes, thus preparing a nematode suspension for later use (wherein each 1mL of suspension contains no less than 100 second-year larva nematodes).
Test treatment and mode: dissolving a compound of the formula I, emamectin benzoate and the line-killing thiazole raw material in acetone to prepare high-concentration mother liquor, respectively diluting the mother liquor into a series of concentrations by using 0.1% Tween 80 water solution containing a proper amount of surfactant according to an equal ratio, carrying out preliminary tests on the compound of the formula I, the emamectin benzoate, the line-killing thiazole and the mixture of the emamectin benzoate, the line-killing thiazole in different proportions, and determining the test concentration range of each mixture. The treatment of each medicine is carried out by setting 5 concentrations according to the content of the effective components, and the comparison is carried out by using the aqueous solution of the solvent which does not contain the same content of the medicine.
The measuring method comprises the following steps: sequentially sucking 3mL of liquid medicine from low concentration to high concentration by a pipette, respectively adding the liquid medicine into a test tube, sucking 3mL of prepared equivalent nematode suspension, adding the liquid medicine and the nematode suspension into the test tube, uniformly mixing the liquid medicine and the nematode suspension in equivalent, transferring 3mL of the mixed liquid into a small hole of a porous biochemical test plate by a pipette, capping, repeating for 4 times every treatment, and setting treatment without a medicament as a control.
The investigation method comprises the following steps: placing the nematodes in a constant-temperature illumination incubator at the temperature of 16 ℃ for 24 hours, checking the death condition of the two-instar larvae of the root-knot nematodes (the nematodes cannot bend when touched by a bamboo filament needle, and death) and taking 1mL of mixed solution from each treatment to observe the death condition of the nematodes under an dissecting mirror, recording the number of the bus worms and the number of the dead nematodes to be investigated, and calculating the corrected death rate.
Statistical analysis: regression analysis was performed by IBM SPSS Statistics statistical software based on the log values of the concentrations of each agent and the corresponding mortality, and the regression equation b value (y=a+bx) was calculated for each agent, and LC was calculated 50 95% confidence limit and R 2 。
Calculating experimental results by adopting IBM SPSS Statistics data processing software, and respectively solving virulence regression equation b values and LC values of 2 single doses and 5 proportioning combinations of the experimental medicaments 50 95% confidence limit and R 2 。
Co-toxicity coefficient (CTC) of the blends was calculated according to the grand cloud Pei method and the type of combined effect was evaluated. CTC.gtoreq.120 shows synergistic effect, CTC.gtoreq.80 shows antagonistic effect, CTC between 80 and 120 shows additive effect.
TABLE 1 indoor assay results for Compounds of formula I, emamectin benzoate and its mixture
Figure BDA0003942822480000051
The compound of the formula I and the emamectin benzoate have different action mechanisms, and the compound is beneficial to overcoming or delaying the occurrence of drug resistance of nematodes, reducing the dosage, lowering the cost and improving the control effect. The test results show that (see table 1), the mixed preparation of the compound of the formula I and the emamectin benzoate has better control effect on the meloidogyne incognita in the range of 1:32-45:1, and the combined effect is shown as synergy.
When the mixing ratio of the compound of the formula I and emamectin benzoate is 1:7-10:1, CTC is more than 145, and the synergy is obvious; when the mixing ratio of the compound of the formula I and emamectin benzoate is 1:1, the maximum CTC value is 170.937, and the activity is the best at the ratio.
Table 2 results of indoor measurements of Compound of formula I, emamectin benzoate and Mixed pair Heterodera avenae Gu Bao
Figure BDA0003942822480000061
The test results show that (see table 2) the mixed preparation of the compound of the formula I and the emamectin benzoate has a better control effect on the nematode Gu Bao, and the combined effect is shown to be synergistic, wherein the CTC value is 171.023 at the maximum when the mixed preparation of the compound of the formula I and the emamectin benzoate is 5:3, and the activity is the best at the mixed preparation.
TABLE 3 results of indoor assays for Compounds of formula I, dimethoxam and their blends against Heterodera Gu Bao
Figure BDA0003942822480000062
The test results show (see Table 3) that the compound of the formula I and the nematicidal thiazole mixed preparation have better control effect on the Heterodera exigua Gu Bao in the range of 1:50-25:1, and the combined effect is synergistic, wherein the CTC value is 171.589 at the maximum when the mixed ratio of the compound of the formula I and the emamectin benzoate is 1:10, and the activity is the best at the ratio.
Formulation examples:
the granule processing technology comprises the following steps: the preparation method comprises the steps of adopting a coating granulation method, uniformly mixing raw materials, a dispersing agent and an auxiliary agent to prepare mother powder, adding the mother powder and a carrier into a coating granulator for stirring, adding a prepared aqueous solution of a binder while stirring, fully and uniformly mixing, discharging, drying and sieving to obtain the granule.
Example 2
4.0% Compound of formula I emamectin benzoate granules (1:1)
The formula comprises the following components: 2.0% of a compound of formula I, 2.0% of emamectin benzoate, 2.5% of polyvinyl acetate, 3.0% of sodium lignin sulfonate, 2.5% of white carbon black and an attapulgite particle carrier.
Example 3
14.0% of the compound of formula I, taken together with the nematicide granule (1:6)
The formula comprises the following components: 2.0% of a compound of formula I, 12.0% of the lineazol, 0.8% of polyvinylpyrrolidone, 3.5% of sodium lignin sulfonate, 8.0% of white carbon black and bentonite particle carrier.
The processing technology of the emulsifiable concentrate comprises the following steps: the raw materials are dissolved in a solvent according to a certain proportion, and then a certain amount of emulsifying agent and other auxiliary agents are added, and the mixture is stirred and mixed to prepare the homogeneous transparent oily liquid, namely the emulsifiable concentrate.
Example 4
16.0% of a compound of the formula I emamectin benzoate in oil (5:3)
The formula comprises the following components: 10.0% of a compound of formula I, 6.0% of emamectin benzoate, 12.0% of tristyrylphenol polyoxyethylene ether, 3.0% of calcium dodecyl benzene sulfonate, 20.0% of cyclohexanone, 20% of DMF and the balance of dimethylbenzene.
Example 5
11.0% of a compound of formula I, trifloxystrobin emulsifiable concentrate (1:10)
The formula comprises the following components: 1.0% of a compound of formula I, 10.0% of the line-killing thiazole, 12.0% of alkylaryl polyoxyethylene polyoxypropylene ether, 3.0% of calcium dodecyl benzene sulfonate, 15.0% of cyclohexanone, 20.0% of N-methylpyrrolidone and 200# solvent oil are used for the balance.
The processing technology of the soluble agent comprises the following steps: the raw materials are dissolved in a solvent according to a certain proportion, and then a certain amount of emulsifying agent and other auxiliary agents are added, and the mixture is stirred and mixed to prepare the homogeneous transparent oily liquid, namely the soluble agent.
Example 6
8.0% Compound of formula I emamectin benzoate solution (5:3)
The formula comprises the following components: 5.0% of a compound of formula I, 3.0% of emamectin benzoate, 4.0% of fatty alcohol polyoxyethylene ether, 12.0% of tristyrylphenol polyoxyethylene ether, 10.0% of dimethyl sulfoxide, 20.0% of cyclohexanone and DMF (dimethyl formamide) are used for the balance.
Example 7
8.0% Compound of formula I, dimethoxam soluble solution (1:7)
The formula comprises the following components: 1.0% of a compound of formula I, 7.0% of the benzothiazole, 4.0% of fatty alcohol polyoxyethylene ether, 12.0% of tristyrylphenol polyoxyethylene ether, 10.0% of propylene carbonate, 20.0% of cyclohexanone and DMF make up the balance
Field efficacy test
Example 8: different mixing pair root knot nematode field control effect test
Test subjects, crops and varieties: tomato root-knot nematode (Meloidogyne spp), which is mainly southern root-knot nematode [ Meloidogyne incongnita (Kofold & White) Chitwood ] through separation and identification,
test materials: the tomato variety is Tianzheng 1567, and the growth condition is good.
The test is carried out in Yang Tuncun tomato vegetable planting shed in Henan Xinxiang city.
Cell area and repetition: 20m per cell 2 Repeated 4 times.
TABLE 4 test design of reagents for test
Figure BDA0003942822480000081
The test was carried out at 18 days 4.2019, and the application was carried out by root irrigation/broadcasting.
The investigation method comprises the following steps: five-point sampling method is adopted, 4 plants are investigated at each point, and the morbidity, disease index and prevention and treatment effect are calculated.
The disease classification method comprises the following steps:
level 0: the root system has no insect gall;
stage 1: small amount of small insect gall is present in the root system;
3 stages: two thirds of the lines are covered with small insect gall;
5 stages: the root system is covered with small insect gall and has secondary insect gall;
7 stages: the root system forms fibrous root clusters.
Disease index = [ Σ (number of disease stages×relative number)/(total number of investigation×7) ]×100;
control effect (%) = [ (CK-PT)/CK ] ×100;
wherein CK is the disease index of the blank control area; PT is the index of the condition in the treatment area of the agent.
Table 5 results of field trials
Figure BDA0003942822480000091
Note that: the control effect (%) of each of the above examples is the average value of each repetition
As shown in Table 5, each example has good effect of preventing and controlling tomato root knot nematode, and the prevention effect of each example on the nematode is over 90% 30 days after the application.
Although embodiments of the present invention have been shown and described, it will be understood by those skilled in the art that various changes, modifications, substitutions and alterations can be made therein without departing from the principles and spirit of the invention, the scope of which is defined in the appended claims and their equivalents.

Claims (10)

1. The nematicidal composition is characterized by comprising an active ingredient A and an active ingredient B, wherein the mass ratio of the active ingredient A to the active ingredient B is 1:50-50:1; the active component A is a compound of formula I
Figure FDA0003942822470000011
The active component B is any one of emamectin benzoate and lineaothiazole.
2. The composition of claim 1, wherein the weight ratio of active ingredient a to active ingredient B is 1:32 to 45:1.
3. The composition according to claim 1, wherein the mass ratio of the compound of formula I to emamectin benzoate is from 1:7 to 15:1;
the mass ratio of the compound of the formula I to the lineazol is 1:30-15:1.
4. The composition according to claim 1, wherein the mass ratio of the compound of formula I to emamectin benzoate is from 1:7 to 10:1;
the mass ratio of the compound of the formula I to the lineazol is 1:10-8:1.
5. The composition according to claim 1, wherein the sum of the weight of the active ingredient a and the weight of the active ingredient B is 0.1-90%, preferably 1-50%, more preferably 1-20% of the composition.
6. The composition of claim 1, wherein the composition comprises, in addition to the active ingredient, an agriculturally acceptable pesticidal adjunct ingredient.
7. The composition of claim 6, wherein the pesticide adjuvant is selected from one or more of wetting agents, dispersants, emulsifiers, thickeners, disintegrants, freezing point depressants, defoamers, solvents, preservatives, stabilizers, synergists, and carriers.
8. The composition of claim 7, wherein the composition is formulated in an agriculturally acceptable dosage form, the dosage form comprising a granule, a cream, a solution.
9. Use of a composition according to any one of claims 1 to 8 for killing plant parasitic nematodes.
10. The use according to claim 9, wherein the nematodes are any one or more of root knot nematodes (Meloidogyne), cyst nematodes (Heterodera), aphelenchus xylophilus (Aphelenchina), stem nematodes (Ditylenchus), root knot nematodes (nacobus) and root rot nematodes (Pratylenchus), pine wood nematodes (Bursa phelenchus xylophilus);
preferably, the nematodes are cyst nematodes and root-knot nematodes;
more preferably, the cyst nematode is a cyst nematode Gu Bao (Cereal cyst nematode, CCN, heterodera avenae Wollenweber 1924); the root-knot nematode is southern root-knot nematode [ Meloidogyne incongnita (Kofold & White) Chitwood ].
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Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111741945A (en) * 2018-02-13 2020-10-02 先正达参股股份有限公司 Novel crystalline forms
CN111742928A (en) * 2020-08-06 2020-10-09 祥霖美丰生物科技(淮安)有限公司 Pesticide composition containing abamectin and cyclobutrifluram and used for preventing and treating root-knot nematode
CN115067341A (en) * 2021-03-15 2022-09-20 江苏龙灯化学有限公司 Nematicidal composition

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111741945A (en) * 2018-02-13 2020-10-02 先正达参股股份有限公司 Novel crystalline forms
CN111742928A (en) * 2020-08-06 2020-10-09 祥霖美丰生物科技(淮安)有限公司 Pesticide composition containing abamectin and cyclobutrifluram and used for preventing and treating root-knot nematode
CN115067341A (en) * 2021-03-15 2022-09-20 江苏龙灯化学有限公司 Nematicidal composition

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