CN106973937B - Nematicidal composition containing cyflumetofen - Google Patents

Nematicidal composition containing cyflumetofen Download PDF

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CN106973937B
CN106973937B CN201710334345.4A CN201710334345A CN106973937B CN 106973937 B CN106973937 B CN 106973937B CN 201710334345 A CN201710334345 A CN 201710334345A CN 106973937 B CN106973937 B CN 106973937B
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cyflumetofen
fluensulfone
nematicidal composition
fosthiazate
effective component
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CN106973937A (en
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王泊理
耿帅峰
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Guangzhou Zhenge Agricultural Science & Technology Co Ltd
Guangdong Zhenge Biotechnology Co Ltd
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Guangzhou Zhenge Agricultural Science & Technology Co Ltd
Guangdong Zhenge Biotechnology Co Ltd
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    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N57/00Biocides, pest repellants or attractants, or plant growth regulators containing organic phosphorus compounds
    • A01N57/26Biocides, pest repellants or attractants, or plant growth regulators containing organic phosphorus compounds having phosphorus-to-nitrogen bonds
    • A01N57/32Biocides, pest repellants or attractants, or plant growth regulators containing organic phosphorus compounds having phosphorus-to-nitrogen bonds containing heterocyclic radicals
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N37/00Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids
    • A01N37/42Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids containing within the same carbon skeleton a carboxylic group or a thio analogue, or a derivative thereof, and a carbon atom having only two bonds to hetero atoms with at the most one bond to halogen, e.g. keto-carboxylic acids
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/72Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with nitrogen atoms and oxygen or sulfur atoms as ring hetero atoms
    • A01N43/74Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with nitrogen atoms and oxygen or sulfur atoms as ring hetero atoms five-membered rings with one nitrogen atom and either one oxygen atom or one sulfur atom in positions 1,3
    • A01N43/781,3-Thiazoles; Hydrogenated 1,3-thiazoles

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  • Life Sciences & Earth Sciences (AREA)
  • Agronomy & Crop Science (AREA)
  • Pest Control & Pesticides (AREA)
  • Plant Pathology (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Dentistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Environmental Sciences (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)

Abstract

The invention relates to a nematicidal composition containing cyflumetofen, which comprises an effective component A of cyflumetofen and an effective component B of fosthiazate or fluensulfone; the weight ratio of the cyflumetofen to the fosthiazate is 20-1: 1-20; the weight ratio of the cyflumetofen to the fluensulfone is 30-1: 1-30, and the total content of effective components is 0.5-80% of the total weight of the composition. The composition can be prepared into agriculturally allowable missible oil, wettable powder, water dispersible granules, microemulsion, suspending agent, emulsion in water and granule formulations. The compound nematicide has reasonable components, good control effect on grain crops, economic crops such as vegetables and fruit trees and forestry underground nematodes, and the control effect on the underground nematodes is not simple superposition of the activities of the components.

Description

Nematicidal composition containing cyflumetofen
Technical Field
The invention relates to the technical field of pesticides, and particularly relates to a nematicidal composition containing cyflumetofen.
Background
Nematodes belong to the phylum of the phylum nematoda, are tiny in shape and can only be observed with the aid of a microscope. Plant parasitic nematodes mainly include: meloidogyne, Heterodera, and Heterodera (pratylenchus). The nematodes are spread through soil or seeds and can damage the root system of the plant; the nematode directly eats the plants, can greatly reduce the absorption of the plants to nutrition and moisture, and provides convenience for the invasion of plant pathogenic bacteria because the nematode eats the plants, so that the nematode interacts with fungi, bacteria and viruses to form compound infection, indirectly transmits the fungi and bacterial diseases caused by other microorganisms, aggravates the harm to crops and causes huge economic pressure.
Cyflumetofen (Cyflumetofen) is a novel acyl acetonitrile acaricide and nematicide which is first reported in 2004 by tsukamur chemical company in japan, is approved for registration and sale in japan for the first time in 2007, and is mainly used for preventing and treating various harmful mites parasitizing on fruit trees, vegetables, tea and ornamental plants. The acaricide has good effect on spider mite eggs and adult mites, has higher activity on nymph mites, and has no cross resistance with the existing acaricide. The cyflumetofen has the action target of a mitochondrial compound II, inhibits the respiration of mites which take succinic acid as a substrate, inhibits the activity difference of the mites, has high selectivity on the mites and low toxicity on vertebrates, does not have phytotoxicity on plants, and is an environment-friendly pesticide. Experiments prove that the cyflumetofen also has better control effect on plant nematodes.
Fosthiazate (fosthazate) is an organic phosphorus nematicide, has contact killing and systemic effects, mainly acts in a mode of inhibiting the synthesis of acetylcholinesterase of root-knot nematodes, and can be used for preventing and treating various root-knot nematodes. The fosthiazate has good quick-acting property, long persistent period, low toxicity and low residue, and is widely applied to agricultural production.
Fluensulfone (fluensulfone) is the only new chemical nematicide developed in more than 20 years recently, belongs to fluoroolefin thioether compounds, acts on nematodes through contact killing, the activity of the nematodes is reduced after contacting the nematodes with the substance, the nematodes are paralyzed, the nematodes stop eating after being exposed for 1h, the infection capacity is reduced, the egg laying capacity is reduced, the egg hatchability is reduced, hatched larvae cannot survive, and the irreversible nematode killing effect can kill the nematodes. The fluensulfone has obvious effect on preventing various plant parasitic nematodes including the root-knot nematodes with serious harm, and has the advantages of low toxicity, low environmental risk and simple use, thus having good development prospect in the aspect of preventing and treating the nematodes.
The single chemical pesticide has the defects of large using amount, quick development of drug resistance, relatively poor drug effect, limited application range and the like, and the application of the single chemical pesticide also belongs to various chemical medicines. At present, no public report about related compounding of cyflumetofen, fosthiazate and fluensulfone is found.
Disclosure of Invention
In view of the above, there is a need to provide a nematicidal composition containing cyflumetofen, which is prepared by compounding cyflumetofen and fosthiazate or fluensulfone, and has the advantages of safety, high efficiency, low toxicity, environmental protection, prolonged pesticide service life, special effect of nematode control, and improvement of crop yield and quality.
The invention adopts the following technical scheme:
a nematicidal composition containing cyflumetofen comprises an effective component A and an effective component B; the active ingredient A is cyflumetofen, the active ingredient B is fosthiazate or fluensulfone, and the weight ratio of the active ingredient A to the active ingredient B is 30-1: 1-30; preferably, the weight ratio of the cyflumetofen to the fosthiazate is 20-1: 1-20; the weight ratio of the cyflumetofen to the fluensulfone is 30-1: 1-30.
Furthermore, the total weight of the effective components accounts for 0.5 to 80 percent of the weight of the pesticide composition.
Further, the total weight of the effective components in the pesticide composition preferably comprises the following components in percentage by weight: 2 to 50 percent.
Furthermore, the nematicidal composition also comprises pesticide preparation auxiliary components, wherein the pesticide preparation auxiliary components comprise at least one of a solvent, a cosolvent, a dispersant, a disintegrant, a wetting agent, an emulsifier, a thickener, a stabilizer, a defoaming agent, a preservative, an antifreeze agent, a carrier and the like, and a plurality of auxiliary agents can be mixed in any proportion.
Further, the solvent and the cosolvent are any one or more of toluene, xylene, methanol, ethanol, n-butanol, isopropanol, turpentine, acetone, cyclohexanone, ethyl acetate, n-octanol, dodecanol, tetradecanol, dimethyl sulfoxide, cyclohexane, dimethylformamide, methyl oleate, fatty acid methyl ester, acetonitrile, soybean oil, turpentine oil, sec-butyl acetate, mixed benzene, solvent oil 100, solvent oil 150, solvent oil 200, water and the like, and the mixed solvent can be formed by a plurality of solvents in any proportion.
Further, the dispersant is one or two of lignosulfonate, alkylphenol polyoxyethylene, formaldehyde condensate sulfate, alkylbenzene sulfonate calcium salt, naphthalene sulfonic acid formaldehyde condensate sodium salt, fatty amine polyoxyethylene ether, fatty acid polyoxyethylene ester, glycerin fatty acid ester polyoxyethylene ether, polyoxyethylene-polyoxypropylene block copolymer and ethylene oxide-propylene oxide block copolymer, and the two dispersants can be combined and mixed in any proportion.
Further, the disintegrating agent is one of sodium alginate, urea, hydroxymethyl starch sodium, dry starch, low-substituted hydroxypropyl cellulose, sodium sulfate, ammonium sulfate and sodium chloride.
Furthermore, the wetting agent is one or more of sodium dodecyl benzene sulfonate, sodium dodecyl sulfate, nekal, alkylbenzene sulfonate, sodium tetradecyl sulfate and Chinese honeylocust fruit powder, and the wetting agents can be mixed in any proportion.
Further, the emulsifier is one or more selected from straight chain or branched chain aliphatic hydrocarbyl sulfonic acid and salt thereof, straight chain or branched chain aliphatic hydrocarbyl ether sulfonic acid and salt thereof, straight chain or branched chain aliphatic hydrocarbyl sulfuric acid and salt thereof, straight chain or branched chain aliphatic hydrocarbyl ether sulfuric acid and salt thereof, straight chain aliphatic alcohol ether, straight chain aliphatic acid polyoxyethylene ester, straight chain aliphatic amine polyoxyethylene ether, sorbitan aliphatic ester polyoxyethylene ether, alkyl polyglycoside, castor oil polyoxyethylene ether, water-soluble starch derivative, water-soluble cellulose derivative and chitosan, and multiple emulsifiers can be mixed in any proportion.
Further, the thickening agent is one or more of xanthan gum, Arabic gum, hydroxymethyl fiber, hydroxyethyl cellulose, magnesium aluminum silicate, polyvinyl alcohol and white carbon black, and when multiple thickening agents are mixed, the thickening agents can be mixed in any proportion.
Further, the stabilizer is selected from one or more of triphenyl phosphate, epoxidized soybean oil, epoxidized chloropropane, BHT, BHA, citric acid, castor oil, salicylic acid, sodium sorbate, butyl glycidyl ether, tolyl glycidyl ether, polyvinyl glycol glycidyl ether, adipic acid or succinic acid, and a plurality of stabilizers can be mixed in any proportion.
Furthermore, the defoaming agent is selected from one or more of silicone oil, silicone, natural oil and fat, tributyl phosphate, polyether C12-C22 higher alcohol or C7-C9 alcohol, and a plurality of defoaming agents can be mixed in any proportion.
Further, the preservative is one of sodium benzoate, sorbitol, citric acid and 2, 6-di-tert-butyl-p-cresol.
Further, the antifreezing agent is one or more selected from ethylene glycol, propylene glycol, glycerol, urea, low molecular weight polyethylene glycol and sorbitol, and multiple antifreezing agents can be mixed in any proportion.
Further, the carrier is one or more of kaolin, diatomite, bentonite, attapulgite, talcum powder, white carbon black, sepiolite and light calcium carbonate, and the carriers can be mixed in any proportion.
Furthermore, the nematicidal composition can be prepared into missible oil, wettable powder, water dispersible granules, microemulsion, suspending agents, emulsion in water, granules and the like.
Furthermore, the nematicidal composition is suitable for controlling nematode infection of plants such as vegetable crops, grain crops, lawns, fruit trees or indoor and outdoor ornamental trees, and particularly for controlling underground nematode infection.
The scheme of the invention can achieve the following beneficial effects:
the cyflumetofen and the fosthiazate or the fluensulfone are compounded to have a synergistic effect, and compared with a single agent used alone, the cyflumetofen and the fosthiazate, the single agent obviously improves the control effect on underground nematodes. The cyflumetofen and the fosthiazate or the fluensulfone are compounded, so that the insecticidal spectrum is expanded, the control effect is improved, the dosage is reduced, the pesticide residue is reduced, the service life of the pesticide is prolonged, the generation of drug resistance of pests is delayed, and the yield and the quality of crops are improved.
Detailed Description
To better demonstrate the nematicidal composition comprising cyflumetofen according to the present invention, further description will be given with reference to the following examples and various tests. It should be noted that, for a person skilled in the art, several variations and modifications can be made without departing from the inventive concept, which falls within the scope of the present invention. Therefore, the protection scope of the present patent shall be subject to the appended claims.
The invention relates to a nematicidal composition containing cyflumetofen and fosthiazate or fluensulfone in a compounding way. The weight ratio of the cyflumetofen to the fosthiazate is 20-1: 1-20, and the weight ratio of the cyflumetofen to the fluensulfone is 30-1: 1-30. The sum of the weight of the cyflumetofen and the fosthiazate or the fluensulfone in the pesticide composition is 0.5 to 80 percent. The following description will use an indoor combined virulence test and pharmacodynamic test.
Indoor bioactivity determination of cucumber root-knot nematode
An insect soaking method: selecting cucumber roots artificially inoculated with cucumber root-knot nematodes, smashing the cucumber roots by using a tissue pounder, sequentially sieving the cucumber roots with 200-mesh, 325-mesh and 500-mesh nematode standard sieves, washing worm eggs on the 500-mesh sieves with sterile water, hatching the eggs in the sterile water, and taking larvae (2-instar larvae) hatched the next day for testing. And sequentially sucking 3ml of liquid medicine into the test tubes from low concentration to high concentration by using a pipette, and then sucking 3ml of prepared equivalent nematode suspension into the test tubes respectively so as to uniformly mix the liquid medicine and the nematode suspension agent in an equivalent manner. Transferring the mixed solution with a certain volume into the small hole of the porous biochemical test plate by using a liquid transfer gun, covering the small hole, and culturing at a constant temperature of 25 ℃. Each treatment was replicated four times, with sterile water as the control treatment. Observing the death condition of the nematodes under a dissecting mirror for 48h, and recording the number of the investigated busworms and the number of dead nematodes. Dead nematodes are stiff and still cannot move in a bending manner when touched by a hair pin. Mortality was calculated and corrected. The test data and results are shown in tables 1 and 3.
Performing regression analysis according to the logarithm value of the concentration of the medicament and the corresponding rate value of the corrected mortality of the plant pathogenic nematodes, and calculating LC of each medicament50And calculating the co-toxicity coefficient (CTC value) of the mixture according to the Sun Yunpei method. See tables 2 and 4.
Measured toxicity index (ATI) ═ standard medicament LC50Test agent LC50)×100
Theoretical virulence index (TTI) ═ A agent virulence index x percent of A in the mixture + B agent virulence index x percent of B in the mixture
Co-toxicity coefficient (CTC) ═ measured toxicity index (ATI) of the mixture/Theoretical Toxicity Index (TTI) of the mixture x 100
Co-toxicity coefficient of the compound agent: CTC is more than or equal to 120 and is judged as synergistic effect; CTC is less than or equal to 80, and is judged to be antagonistic; 80 < CTC < 120 is judged as additive.
TABLE 1 insecticidal determination of cyflumetofen and fosthiazate compounded insecticidal situation by the insect immersion method
TABLE 2 indoor toxicity assay results for cucumber root-knot nematodes paired with cyflumetofen and fosthiazate
As can be seen from the table 2, when the cyflumetofen and the fosthiazate are compounded, the cyflumetofen and the fosthiazate have additive or synergistic effect within the ratio of 30-1: 1-30, particularly within the ratio of 20-1: 1-20, the cotoxicity coefficient (CTC) is more than 120, and the cyflumetofen and the fosthiazate have synergistic effect on the meloidogyne cucumis. When the mass ratio of the cyflumetofen to the fosthiazate is 1:1, LC50Minimum i.e. 2.74, CTC maximum i.e. 198.21. Analysis of all data in table 2 shows that the formulation of cyflumetofen and fosthiazate is reasonable and feasible.
TABLE 3 insecticidal determination of combinations of cyflumetofen and fluensulfone by the insect immersion method
Table 4 shows the indoor toxicity test results of the compounded cyflumetofen and fluensulfone on the root-knot nematodes of cucumbers.
As can be seen from Table 4, after indoor toxicological test, the co-toxicity coefficient (CTC) of the compounded cyflumetofen and fluensulfone is greater than 120 within the range of 30-1: 1-30; especially when the compounding ratio is 1:2, LC50Minimum 2.54, CTC maximum 191.70. Therefore, the compounded cyflumetofen and the fluensulfone show the synergistic effect on the root-knot nematodes of cucumbers. The data analysis in the table 4 shows that the formulation of cyflumetofen and fluensulfone has rationality and feasibility.
The nematicidal composition can be prepared into dosage forms such as missible oil, wettable powder, water dispersible granules, microemulsion, suspending agent, emulsion in water, granules and the like which are suitable for agricultural production. The following percentages in the formulas of the specific examples are mass ratios.
Example 1: 30% cyflumetofen-fosthiazate missible oil
Weighing 25% of cyflumetofen, 5% of fosthiazate, 3% of Nongru No. 500 (calcium dodecylbenzene sulfonate), 4% of Nongru No. 600 (styrylphenol polyoxyethylene ether), 3% of alkylphenol polyoxyethylene ether, 5% of sodium ricinoleate, 8% of dimethyl sulfoxide (cosolvent) and the balance of xylene (solvent). Mixing and stirring the cyflumetofen, the fosthiazate, the cosolvent and the solvent to completely dissolve the cyflumetofen and the fosthiazate, adding other auxiliary agents, and stirring uniformly to obtain the 30 percent cyflumetofen-fosthiazate emulsifiable solution.
Example 2: 30% cyflumetofen-fluensulfone missible oil
Weighing 20% of cyflumetofen, 10% of fluensulfone, 5% of sodium dodecyl sulfate, 8% of styrylphenol polyoxyethylene ether, 5% of sodium ricinoleate, 10% of dimethyl sulfoxide (cosolvent) and the balance of xylene (solvent). Mixing and stirring the cyflumetofen, the fluensulfone, the cosolvent and the solvent to completely dissolve the cyflumetofen and the fluensulfone, adding other auxiliary agents, and stirring uniformly to obtain the 30 percent cyflumetofen-fluensulfone missible oil.
Example 3: 20% cyflumetofen-fosthiazate aqueous emulsion
Weighing 15% of cyflumetofen, 5% of fosthiazate, 5% of agricultural emulsion 2201#, 7% of fatty alcohol-polyoxyethylene ether, 8% of sodium salt of a naphthalene sulfonic acid formaldehyde condensate, 1% of ethylene glycol, 5% of dimethylbenzene, 0.5% of benzoic acid, 0.2% of xanthan gum and the balance of deionized water. Mixing and dissolving the cyflumetofen, the fosthiazate, the emulsifier, the antifreeze, the organic solvent and the like, and adding the balance of deionized water in the high-speed shearing process to prepare the 20 percent cyflumetofen-fosthiazate aqueous emulsion.
Example 4: 20% cyflumetofen-fluensulfone aqueous emulsion
Weighing 15% of cyflumetofen, 5% of fluensulfone, 5% of sodium dodecyl sulfate, 8% of alkylphenol polyoxyethylene, 7% of sodium naphthalene sulfonic acid formaldehyde condensate, 1% of ethylene glycol, 5% of dimethylbenzene, 0.5% of benzoic acid, 0.2% of xanthan gum and the balance of deionized water. Mixing and dissolving the cyflumetofen, the fluensulfone, the emulsifier, the antifreezing agent, the organic solvent and the like, and adding the balance of deionized water in the high-speed shearing process to prepare the 20 percent cyflumetofen-fluensulfone aqueous emulsion.
Example 5: microemulsion of 22% cyflumetofen and fosthiazate
Weighing 20% of cyflumetofen, 2% of fosthiazate, 10% of xylene, 5% of dimethyl sulfoxide, 5% of agricultural milk 500#, 3% of agricultural milk 600#, 5% of castor oil polyoxyethylene ether, 7% of methylene dinaphthalene sodium sulfonate, 3% of n-butyl alcohol, 2% of tributyl phosphate, 3% of PEG400 and the balance of deionized water. And mixing the dimethylbenzene and the dimethyl sulfoxide according to the proportion, dissolving the corresponding cyflumetofen in an organic solvent, adding the rest fosthiazate, the emulsifier, the defoamer and the stabilizer, stirring to uniformly mix, and adding the rest deionized water in the stirring process to prepare the 22% cyflumetofen-fosthiazate microemulsion.
Example 6: microemulsion of 30% cyflumetofen and fluensulfone
Weighing 20% of cyflumetofen, 10% of fluensulfone, 10% of xylene, 10% of dimethyl sulfoxide, 8% of Nongru 500#, 5% of Nongru 600#, 5% of alkylphenol polyoxyethylene ether, 7% of sodium naphthalene sulfonate formaldehyde condensate, 3% of n-butyl alcohol, 2% of tributyl phosphate, 3% of PEG400 and the balance of deionized water. Mixing the dimethylbenzene and the dimethyl sulfoxide according to the proportion, dissolving the corresponding cyflumetofen and the fluensulfone in an organic solvent, adding the rest of the emulsifier, the defoaming agent and the stabilizer, stirring to uniformly mix, and adding the rest of deionized water in the stirring process to prepare the 30 percent cyflumetofen-fluensulfone microemulsion.
Example 7: 6% cyflumetofen-fosthiazate granules
Weighing 3% of cyflumetofen, 3% of fosthiazate, 4% of sodium dodecyl sulfate, 6% of sodium butylnaphthalene sulfonate, 2% of sodium lignosulfonate, 10% of polyvinyl alcohol, 10% of polyvinylpyrrolidone and the balance of attapulgite. And uniformly mixing the materials in a mixing cylinder, kneading the materials by using a kneading granulator, forming and granulating, and drying and screening the granules by using a fluidized bed to prepare the 6% cyflumetofen-fosthiazate granules.
Example 8: 6% cyflumetofen-fluensulfone granules
Weighing 2% of cyflumetofen, 4% of fluensulfone, 3% of sodium methylene dinaphthalene sulfonate, 6% of sodium butyl naphthalene sulfonate, 2% of sodium lignin sulfonate, 10% of polyvinyl alcohol, 10% of polyvinylpyrrolidone and the balance of attapulgite. The materials are evenly mixed in a mixing cylinder, a kneading granulator is used for kneading and forming for granulation, and then the granules are dried and screened by a fluidized bed, so that the 6 percent cyflumetofen-fluensulfone granules are prepared.
Example 9: 42% cyflumetofen-fosthiazate water dispersible granule
Weighing 40% of cyflumetofen, 2% of fosthiazate, 2% of sodium dodecyl sulfate, 6% of sodium butylnaphthalene sulfonate, 6% of sodium lignosulfonate, 8% of polyvinyl alcohol, 2% of ammonium sulfate, 1% of white carbon black and the balance of kaolin. Adding the materials into a mixer, uniformly mixing, then carrying out airflow crushing, adding a small amount of water after crushing, fully and uniformly stirring, carrying out extrusion granulation, and drying to obtain the 42% cyflumetofen-fosthiazate water dispersible granule.
Example 10: 31% cyflumetofen-fluensulfone water dispersible granule
Weighing 30% of cyflumetofen, 1% of fosthiazate, 2% of sodium dodecyl sulfate, 3% of sodium butylnaphthalene sulfonate, 5% of sodium lignosulfonate, 5% of polyvinyl alcohol, 2% of ammonium sulfate, 0.5% of white carbon black and the balance of kaolin. Adding the materials into a mixer, uniformly mixing, then carrying out airflow crushing, adding a small amount of water after crushing, fully and uniformly stirring, carrying out extrusion granulation, and drying to obtain the 31% cyflumetofen-fluensulfone water dispersible granule.
Prevention and control of cucumber root-knot nematode by field test
The root-knot nematode damage is serious when the method is tested in the cucumber production base in the high key area of Zhaoqing, Guangdong. The experiment is totally provided with 9 treatments (the nematode damage in the treatment area is basically uniform, the ecological environment is the same), the treatment is carried out by adopting a spreading mode, after the treatment of the medicament, a random sampling method is adopted, 5 points are sampled in each cell, 3 cucumber seedlings are randomly investigated in each point, 15 cucumber seedlings are counted, the cucumber roots are dug out, and the root-knot nematode damage level is investigated and recorded. The investigation method is carried out according to the pesticide field efficacy test criteria.
Level 0: no visible nodules or egg masses;
level 1: the total length of the root nodules accounts for 1% -24% of the total root length;
and 2, stage: the total length of the root nodules accounts for 25% -49% of the total root length;
and 3, level: the total length of the root nodules accounts for 50% -74% of the total root length;
4, level: the total length of the root nodules accounts for 75% -100% of the total root length;
disease index ═ Σ (number of disease roots at each stage × number of relative stage)/(total number of investigated plants × 4) × 100;
the preventing and treating effect (%) is (1-treatment disease index/control disease index) × 100.
The method for evaluating the synergistic effect according to the Gowing method has the following formula:
E0=X+Y-X*Y/100
in the formula: the X is the effective component A, and the effect of preventing and controlling the cucumber root knot nematode disease when the A is singly used at a certain concentration is achieved; y is the control effect of the effective component B on the root knot nematode disease of the cucumber when the effective component B is singly used at a certain concentration B; e0 is the theoretical value of the control effect of the root knot nematode disease of cucumber when the effective component A and the effective component B are used in the mixed concentration (a + B).
E is an observed value of the control effect of the cucumber root knot nematode by the concentration (a + B) of the effective component A and the effective component B.
Evaluation criteria: when E-E0 is more than 10%, the synergistic effect is expressed; when the concentration is more than or equal to-10 percent and less than or equal to E-E0, the synergistic and additive effect is shown; when E-E0 is < -10%, it shows synergistic antagonistic action. Table 5 shows the results of the tests for controlling cucumber root knot nematode disease in the field with each treatment agent:
TABLE 5
Note: examples 7 and 8 correspond to 6% cyflumetofen-fosthiazate granules and 6% cyflumetofen-fluensulfone granules, respectively.
Table 6 shows the evaluation of the control effect of 6% cyflumetofen-fosthiazate granules and 6% cyflumetofen-fluensulfone granules on the field test of meloidogyne cucumis according to the Gowing method.
As can be seen from Table 6, the compounded preparation of cyflumetofen and fosthiazate or fluensulfone is used for preventing and treating cucumber root-knot nematodes, and the effect is obviously better than that of a single agent. The compound nematicidal composition has a synergistic effect and can be popularized and used in agriculture.
The nematicidal composition containing cyflumetofen can be applied to control of underground nematodes in grain crops, vegetables, fruit trees and other economic crops and forestry.
The foregoing is a more detailed description of the invention in connection with specific preferred embodiments and it is not intended that the invention be limited to these specific details. For those skilled in the art to which the invention pertains, several simple deductions or substitutions can be made without departing from the spirit of the invention, and all shall be considered as belonging to the protection scope of the invention.

Claims (6)

1. A nematicidal composition containing cyflumetofen is characterized in that: the pesticide composition comprises an effective component A, an effective component B and an auxiliary component of a pesticide preparation, wherein the effective component A is cyflumetofen, the effective component B is fluensulfone, and the weight ratio of the cyflumetofen to the fluensulfone is 30-1: 1-30.
2. A nematicidal composition comprising cyflumetofen according to claim 1 wherein: the total weight of the effective components accounts for 0.5 to 80 percent of the weight of the nematicidal composition.
3. A nematicidal composition comprising cyflumetofen according to claim 2 wherein: the weight percentage of the total weight of the effective components in the nematicidal composition is 2 to 50 percent.
4. A nematicidal composition comprising cyflumetofen according to claim 1 wherein: the auxiliary components of the pesticide preparation are selected from at least one of a solvent, a cosolvent, a dispersant, a disintegrant, a wetting agent, an emulsifier, a thickener, a stabilizer, a defoaming agent, a preservative, an antifreeze agent and a carrier.
5. A nematicidal composition comprising cyflumetofen according to any one of claims 1 to 4 wherein: the nematicidal composition is prepared into missible oil, wettable powder, water dispersible granules, microemulsion, suspending agents, emulsion in water and granules.
6. A nematicidal composition comprising cyflumetofen according to any one of claims 1 to 4 for use in controlling nematode infestation of plants.
CN201710334345.4A 2017-05-12 2017-05-12 Nematicidal composition containing cyflumetofen Active CN106973937B (en)

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CN107535498A (en) * 2017-08-14 2018-01-05 广东真格生物科技有限公司 A kind of composition pesticide containing cyflumetofen and fluopyram and its application
CN114885948B (en) * 2022-06-20 2023-04-07 广西壮族自治区农业科学院 Nematicidal composition for preventing and treating taro root knot nematode disease

Citations (2)

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Publication number Priority date Publication date Assignee Title
JP2009209124A (en) * 2008-02-06 2009-09-17 Nissan Chem Ind Ltd Insect- or acarian-controlling composition
CN103493841A (en) * 2013-10-11 2014-01-08 江苏龙灯化学有限公司 Insecticidal composition

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2009209124A (en) * 2008-02-06 2009-09-17 Nissan Chem Ind Ltd Insect- or acarian-controlling composition
CN103493841A (en) * 2013-10-11 2014-01-08 江苏龙灯化学有限公司 Insecticidal composition

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