CN116138364A - Basic mineral substance growth promoter for chicks, and preparation method, application and use method thereof - Google Patents
Basic mineral substance growth promoter for chicks, and preparation method, application and use method thereof Download PDFInfo
- Publication number
- CN116138364A CN116138364A CN202310035816.7A CN202310035816A CN116138364A CN 116138364 A CN116138364 A CN 116138364A CN 202310035816 A CN202310035816 A CN 202310035816A CN 116138364 A CN116138364 A CN 116138364A
- Authority
- CN
- China
- Prior art keywords
- chicks
- parts
- growth promoter
- mineral substance
- fermentation
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 229910052500 inorganic mineral Inorganic materials 0.000 title claims abstract description 132
- 239000011707 mineral Substances 0.000 title claims abstract description 132
- 239000000126 substance Substances 0.000 title claims abstract description 86
- 239000007952 growth promoter Substances 0.000 title claims abstract description 82
- 238000000034 method Methods 0.000 title claims abstract description 15
- 238000002360 preparation method Methods 0.000 title abstract description 12
- 235000010755 mineral Nutrition 0.000 claims abstract description 131
- 241000287828 Gallus gallus Species 0.000 claims abstract description 43
- 235000013330 chicken meat Nutrition 0.000 claims abstract description 43
- 239000006041 probiotic Substances 0.000 claims abstract description 42
- 235000018291 probiotics Nutrition 0.000 claims abstract description 42
- 240000008042 Zea mays Species 0.000 claims abstract description 38
- 235000005824 Zea mays ssp. parviglumis Nutrition 0.000 claims abstract description 38
- 235000002017 Zea mays subsp mays Nutrition 0.000 claims abstract description 38
- 235000005822 corn Nutrition 0.000 claims abstract description 38
- WCUXLLCKKVVCTQ-UHFFFAOYSA-M Potassium chloride Chemical compound [Cl-].[K+] WCUXLLCKKVVCTQ-UHFFFAOYSA-M 0.000 claims abstract description 34
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 25
- 240000004808 Saccharomyces cerevisiae Species 0.000 claims abstract description 21
- 239000005715 Fructose Substances 0.000 claims abstract description 20
- 229930091371 Fructose Natural products 0.000 claims abstract description 20
- RFSUNEUAIZKAJO-ARQDHWQXSA-N Fructose Chemical compound OC[C@H]1O[C@](O)(CO)[C@@H](O)[C@@H]1O RFSUNEUAIZKAJO-ARQDHWQXSA-N 0.000 claims abstract description 20
- 235000013312 flour Nutrition 0.000 claims abstract description 20
- 235000012907 honey Nutrition 0.000 claims abstract description 20
- UIIMBOGNXHQVGW-DEQYMQKBSA-M Sodium bicarbonate-14C Chemical compound [Na+].O[14C]([O-])=O UIIMBOGNXHQVGW-DEQYMQKBSA-M 0.000 claims abstract description 19
- 235000011844 whole wheat flour Nutrition 0.000 claims abstract description 18
- UXVMQQNJUSDDNG-UHFFFAOYSA-L Calcium chloride Chemical compound [Cl-].[Cl-].[Ca+2] UXVMQQNJUSDDNG-UHFFFAOYSA-L 0.000 claims abstract description 17
- HCHKCACWOHOZIP-UHFFFAOYSA-N Zinc Chemical compound [Zn] HCHKCACWOHOZIP-UHFFFAOYSA-N 0.000 claims abstract description 17
- 239000001110 calcium chloride Substances 0.000 claims abstract description 17
- 229910001628 calcium chloride Inorganic materials 0.000 claims abstract description 17
- 239000001103 potassium chloride Substances 0.000 claims abstract description 17
- 235000011164 potassium chloride Nutrition 0.000 claims abstract description 17
- 239000011701 zinc Substances 0.000 claims abstract description 15
- 229910052725 zinc Inorganic materials 0.000 claims abstract description 15
- 238000004519 manufacturing process Methods 0.000 claims abstract description 12
- 235000014680 Saccharomyces cerevisiae Nutrition 0.000 claims abstract description 9
- 238000000855 fermentation Methods 0.000 claims description 27
- 230000004151 fermentation Effects 0.000 claims description 27
- 239000000203 mixture Substances 0.000 claims description 20
- 241000194031 Enterococcus faecium Species 0.000 claims description 18
- 244000063299 Bacillus subtilis Species 0.000 claims description 17
- 235000014469 Bacillus subtilis Nutrition 0.000 claims description 17
- 239000003795 chemical substances by application Substances 0.000 claims description 17
- JVTAAEKCZFNVCJ-UHFFFAOYSA-N lactic acid Chemical compound CC(O)C(O)=O JVTAAEKCZFNVCJ-UHFFFAOYSA-N 0.000 claims description 16
- 241000235342 Saccharomycetes Species 0.000 claims description 13
- 230000002183 duodenal effect Effects 0.000 claims description 12
- 241000894006 Bacteria Species 0.000 claims description 11
- 241000186660 Lactobacillus Species 0.000 claims description 9
- 229940039696 lactobacillus Drugs 0.000 claims description 9
- 239000004310 lactic acid Substances 0.000 claims description 8
- 235000014655 lactic acid Nutrition 0.000 claims description 8
- 108010028780 Complement C3 Proteins 0.000 claims description 7
- 102000016918 Complement C3 Human genes 0.000 claims description 7
- 108010028778 Complement C4 Proteins 0.000 claims description 7
- 230000000529 probiotic effect Effects 0.000 claims description 5
- 239000000463 material Substances 0.000 claims description 3
- 241001591005 Siga Species 0.000 claims description 2
- 230000036039 immunity Effects 0.000 abstract description 10
- 230000029087 digestion Effects 0.000 abstract description 7
- 230000007413 intestinal health Effects 0.000 abstract description 5
- 230000000052 comparative effect Effects 0.000 description 31
- 230000000968 intestinal effect Effects 0.000 description 15
- UIIMBOGNXHQVGW-UHFFFAOYSA-M Sodium bicarbonate Chemical compound [Na+].OC([O-])=O UIIMBOGNXHQVGW-UHFFFAOYSA-M 0.000 description 14
- 230000000694 effects Effects 0.000 description 13
- 230000004584 weight gain Effects 0.000 description 11
- 235000019786 weight gain Nutrition 0.000 description 11
- 150000001875 compounds Chemical class 0.000 description 10
- 210000001519 tissue Anatomy 0.000 description 9
- 238000012360 testing method Methods 0.000 description 8
- 241001465754 Metazoa Species 0.000 description 7
- 229940027941 immunoglobulin g Drugs 0.000 description 7
- 235000017557 sodium bicarbonate Nutrition 0.000 description 7
- 229910000030 sodium bicarbonate Inorganic materials 0.000 description 7
- 238000008157 ELISA kit Methods 0.000 description 6
- 230000009286 beneficial effect Effects 0.000 description 6
- 238000002156 mixing Methods 0.000 description 6
- 230000001737 promoting effect Effects 0.000 description 6
- 230000035882 stress Effects 0.000 description 6
- 230000003442 weekly effect Effects 0.000 description 6
- 238000010521 absorption reaction Methods 0.000 description 5
- 150000002500 ions Chemical class 0.000 description 5
- 235000013372 meat Nutrition 0.000 description 5
- 239000000047 product Substances 0.000 description 5
- 230000009469 supplementation Effects 0.000 description 5
- 231100000331 toxic Toxicity 0.000 description 5
- 230000002588 toxic effect Effects 0.000 description 5
- 210000002966 serum Anatomy 0.000 description 4
- 102000004190 Enzymes Human genes 0.000 description 3
- 108090000790 Enzymes Proteins 0.000 description 3
- 108060003951 Immunoglobulin Proteins 0.000 description 3
- 230000004913 activation Effects 0.000 description 3
- 239000003242 anti bacterial agent Substances 0.000 description 3
- 230000004888 barrier function Effects 0.000 description 3
- 239000002131 composite material Substances 0.000 description 3
- 238000011161 development Methods 0.000 description 3
- 239000003651 drinking water Substances 0.000 description 3
- 235000020188 drinking water Nutrition 0.000 description 3
- 239000003792 electrolyte Substances 0.000 description 3
- 235000021050 feed intake Nutrition 0.000 description 3
- 235000013305 food Nutrition 0.000 description 3
- 102000018358 immunoglobulin Human genes 0.000 description 3
- 229940099472 immunoglobulin a Drugs 0.000 description 3
- 235000013348 organic food Nutrition 0.000 description 3
- 235000021441 organic meat Nutrition 0.000 description 3
- 239000013589 supplement Substances 0.000 description 3
- CURLTUGMZLYLDI-UHFFFAOYSA-N Carbon dioxide Chemical compound O=C=O CURLTUGMZLYLDI-UHFFFAOYSA-N 0.000 description 2
- 206010059866 Drug resistance Diseases 0.000 description 2
- 206010061218 Inflammation Diseases 0.000 description 2
- 241000700605 Viruses Species 0.000 description 2
- JIAARYAFYJHUJI-UHFFFAOYSA-L Zinc chloride Inorganic materials [Cl-].[Cl-].[Zn+2] JIAARYAFYJHUJI-UHFFFAOYSA-L 0.000 description 2
- 230000002180 anti-stress Effects 0.000 description 2
- 229940088710 antibiotic agent Drugs 0.000 description 2
- 238000010241 blood sampling Methods 0.000 description 2
- 238000009395 breeding Methods 0.000 description 2
- 230000001488 breeding effect Effects 0.000 description 2
- 239000000969 carrier Substances 0.000 description 2
- 230000008859 change Effects 0.000 description 2
- 210000002249 digestive system Anatomy 0.000 description 2
- 230000002496 gastric effect Effects 0.000 description 2
- 239000005556 hormone Substances 0.000 description 2
- 229940088597 hormone Drugs 0.000 description 2
- 230000003053 immunization Effects 0.000 description 2
- 238000002649 immunization Methods 0.000 description 2
- 230000004054 inflammatory process Effects 0.000 description 2
- 210000004347 intestinal mucosa Anatomy 0.000 description 2
- 230000009545 invasion Effects 0.000 description 2
- 230000033001 locomotion Effects 0.000 description 2
- 230000003340 mental effect Effects 0.000 description 2
- 230000000813 microbial effect Effects 0.000 description 2
- 231100000252 nontoxic Toxicity 0.000 description 2
- 230000003000 nontoxic effect Effects 0.000 description 2
- 150000007524 organic acids Chemical class 0.000 description 2
- 230000011164 ossification Effects 0.000 description 2
- 230000001766 physiological effect Effects 0.000 description 2
- 230000036544 posture Effects 0.000 description 2
- 238000011002 quantification Methods 0.000 description 2
- 239000002994 raw material Substances 0.000 description 2
- 230000003248 secreting effect Effects 0.000 description 2
- 230000001502 supplementing effect Effects 0.000 description 2
- 239000011592 zinc chloride Substances 0.000 description 2
- 235000005074 zinc chloride Nutrition 0.000 description 2
- 208000035240 Disease Resistance Diseases 0.000 description 1
- 208000015580 Increased body weight Diseases 0.000 description 1
- 229930040373 Paraformaldehyde Natural products 0.000 description 1
- 230000005856 abnormality Effects 0.000 description 1
- 230000003213 activating effect Effects 0.000 description 1
- 239000000654 additive Substances 0.000 description 1
- 230000000996 additive effect Effects 0.000 description 1
- 230000000844 anti-bacterial effect Effects 0.000 description 1
- 230000000840 anti-viral effect Effects 0.000 description 1
- 230000003115 biocidal effect Effects 0.000 description 1
- 210000004369 blood Anatomy 0.000 description 1
- 239000008280 blood Substances 0.000 description 1
- 239000001569 carbon dioxide Substances 0.000 description 1
- 229910002092 carbon dioxide Inorganic materials 0.000 description 1
- 230000003197 catalytic effect Effects 0.000 description 1
- 238000006243 chemical reaction Methods 0.000 description 1
- 230000008645 cold stress Effects 0.000 description 1
- 238000012258 culturing Methods 0.000 description 1
- 238000005520 cutting process Methods 0.000 description 1
- 230000003247 decreasing effect Effects 0.000 description 1
- 238000001514 detection method Methods 0.000 description 1
- 230000035622 drinking Effects 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 229940079593 drug Drugs 0.000 description 1
- 210000001198 duodenum Anatomy 0.000 description 1
- 238000004043 dyeing Methods 0.000 description 1
- 201000006549 dyspepsia Diseases 0.000 description 1
- 239000003337 fertilizer Substances 0.000 description 1
- 238000009472 formulation Methods 0.000 description 1
- 210000001035 gastrointestinal tract Anatomy 0.000 description 1
- 230000002068 genetic effect Effects 0.000 description 1
- 230000036541 health Effects 0.000 description 1
- 230000008642 heat stress Effects 0.000 description 1
- 229910001385 heavy metal Inorganic materials 0.000 description 1
- -1 hormone and enzyme Chemical class 0.000 description 1
- 239000003688 hormone derivative Substances 0.000 description 1
- 230000036737 immune function Effects 0.000 description 1
- 239000004615 ingredient Substances 0.000 description 1
- 230000015788 innate immune response Effects 0.000 description 1
- 210000000936 intestine Anatomy 0.000 description 1
- 238000009318 large scale farming Methods 0.000 description 1
- 230000003902 lesion Effects 0.000 description 1
- 239000007788 liquid Substances 0.000 description 1
- 208000030159 metabolic disease Diseases 0.000 description 1
- 230000002503 metabolic effect Effects 0.000 description 1
- 239000002366 mineral element Substances 0.000 description 1
- 210000004877 mucosa Anatomy 0.000 description 1
- 210000004400 mucous membrane Anatomy 0.000 description 1
- 235000015816 nutrient absorption Nutrition 0.000 description 1
- 235000006286 nutrient intake Nutrition 0.000 description 1
- 235000015097 nutrients Nutrition 0.000 description 1
- 235000016709 nutrition Nutrition 0.000 description 1
- 235000003715 nutritional status Nutrition 0.000 description 1
- 230000003647 oxidation Effects 0.000 description 1
- 238000007254 oxidation reaction Methods 0.000 description 1
- 229920002866 paraformaldehyde Polymers 0.000 description 1
- 239000000575 pesticide Substances 0.000 description 1
- 238000004321 preservation Methods 0.000 description 1
- 230000008569 process Effects 0.000 description 1
- 102000004169 proteins and genes Human genes 0.000 description 1
- 108090000623 proteins and genes Proteins 0.000 description 1
- 238000011160 research Methods 0.000 description 1
- 238000002791 soaking Methods 0.000 description 1
- 238000010186 staining Methods 0.000 description 1
- 239000008223 sterile water Substances 0.000 description 1
- 238000003860 storage Methods 0.000 description 1
- 239000006228 supernatant Substances 0.000 description 1
- 210000004876 tela submucosa Anatomy 0.000 description 1
- 235000013343 vitamin Nutrition 0.000 description 1
- 239000011782 vitamin Substances 0.000 description 1
- 229940088594 vitamin Drugs 0.000 description 1
- 229930003231 vitamin Natural products 0.000 description 1
Images
Classifications
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K50/00—Feeding-stuffs specially adapted for particular animals
- A23K50/70—Feeding-stuffs specially adapted for particular animals for birds
- A23K50/75—Feeding-stuffs specially adapted for particular animals for birds for poultry
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; CARE OF BIRDS, FISHES, INSECTS; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K67/00—Rearing or breeding animals, not otherwise provided for; New breeds of animals
- A01K67/02—Breeding vertebrates
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K10/00—Animal feeding-stuffs
- A23K10/10—Animal feeding-stuffs obtained by microbiological or biochemical processes
- A23K10/12—Animal feeding-stuffs obtained by microbiological or biochemical processes by fermentation of natural products, e.g. of vegetable material, animal waste material or biomass
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K10/00—Animal feeding-stuffs
- A23K10/20—Animal feeding-stuffs from material of animal origin
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K10/00—Animal feeding-stuffs
- A23K10/30—Animal feeding-stuffs from material of plant origin, e.g. roots, seeds or hay; from material of fungal origin, e.g. mushrooms
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K10/00—Animal feeding-stuffs
- A23K10/30—Animal feeding-stuffs from material of plant origin, e.g. roots, seeds or hay; from material of fungal origin, e.g. mushrooms
- A23K10/37—Animal feeding-stuffs from material of plant origin, e.g. roots, seeds or hay; from material of fungal origin, e.g. mushrooms from waste material
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K20/00—Accessory food factors for animal feeding-stuffs
- A23K20/10—Organic substances
- A23K20/163—Sugars; Polysaccharides
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K20/00—Accessory food factors for animal feeding-stuffs
- A23K20/20—Inorganic substances, e.g. oligoelements
- A23K20/24—Compounds of alkaline earth metals, e.g. magnesium
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K20/00—Accessory food factors for animal feeding-stuffs
- A23K20/20—Inorganic substances, e.g. oligoelements
- A23K20/30—Oligoelements
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K40/00—Shaping or working-up of animal feeding-stuffs
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P60/00—Technologies relating to agriculture, livestock or agroalimentary industries
- Y02P60/80—Food processing, e.g. use of renewable energies or variable speed drives in handling, conveying or stacking
- Y02P60/87—Re-use of by-products of food processing for fodder production
Abstract
The invention belongs to the technical field of feeds, and particularly relates to an alkaline mineral substance growth promoter for chickens, and a preparation method, application and a use method thereof. The invention provides an alkaline mineral substance growth promoter for chickens, which comprises the following components: potassium chloride, sodium bicarbonate, yeast zinc, calcium chloride, fructose, honey, corn flour, corn bran, whole wheat flour and probiotics. The alkaline mineral substance growth promoter for the chicks can promote the chicks to grow, improve the immunity of the chicks and improve the digestion capacity of the chicks. The results of the examples show that: the chick alkaline mineral substance growth promoter can obviously increase the weight of the chick, reduce the feed-to-meat ratio, enhance the immunity and improve the intestinal health when the chick is fed with water, thereby improving the production performance of the chick.
Description
Technical Field
The invention belongs to the technical field of feeds, and particularly relates to an alkaline mineral substance growth promoter for chickens, and a preparation method, application and a use method thereof.
Background
Organic foods, also called ecological foods, are generally intended to be foods obtained on the basis of organic agriculture production systems, while organic agriculture refers to agriculture in which toxic pesticides, fertilizers, antibiotics, synthetic hormones are not used in the production process. Organic foods are one of the fastest growing segments of the food market, and organic meats are the fastest growing category of organic foods. Although the demand for antibiotic-free organic meats has grown at a rate of about 20% per year, the complexity and high cost of organic meat production has remained a significant factor limiting the development of the organic industry.
The brooding period is a key period of the whole raising process, and the quality of the chicks is directly related to the quality of the bred chick group. At present, large-scale chicken breeding in China faces a plurality of problems, such as the increase of intestinal tract burden caused by directional breeding of genetic characters; feed mold, stress, frequent immunization programs and the like cause the chicks to be stimulated, and the production performance is reduced. Therefore, there is an urgent need to develop an alkaline mineral growth promoter for chickens, which can improve growth performance.
Disclosure of Invention
The invention aims to provide the basic mineral substance growth promoter for the chicks, which has the advantages of easily available raw materials and low cost, and can be used for increasing the weight of the chicks, reducing the feed-to-meat ratio of the chicks and increasing the contents of the duodenal immune substances complement C3, complement C4, igG, igM and SIgA when being used for feeding the chicks.
In order to solve the technical problems, the invention provides the following technical scheme:
the invention provides an alkaline mineral substance growth promoter for chickens, which comprises the following components: potassium chloride, sodium bicarbonate, yeast zinc, calcium chloride, fructose, honey, corn flour, corn bran, whole wheat flour and probiotics.
Preferably, the composition comprises the following components in parts by mass: 8 to 12 parts of potassium chloride, 20 to 25 parts of sodium bicarbonate, 0.01 to 0.04 part of yeast zinc, 0.05 to 0.10 part of calcium chloride, 20 to 25 parts of fructose, 15 to 20 parts of honey, 20 to 25 parts of corn flour, 490 to 510 parts of corn bran, 490 to 510 parts of whole wheat flour and 5 to 10 parts of probiotics.
Preferably, the probiotics comprise one or more of lactic acid bacteria, yeast, enterococcus faecium and bacillus subtilis.
Preferably, when the probiotics comprise lactobacillus, saccharomycete, enterococcus faecium and bacillus subtilis, the mass ratio of the lactobacillus to the saccharomycete to the enterococcus faecium to the bacillus subtilis is 1.25-2.6:1.5-2.8:1.25-2.6:1-2; the viable count of the lactic acid bacteria is 2-3 x 10 10 CFU/g, the viable count of the saccharomycetes is 2-2.5 x 10 10 CFU/g, the viable count of the enterococcus faecium is 2-2.5 x 10 9 CFU/g, the viable count of the bacillus subtilis is 2-2.5 x 10 10 CFU/g。
The invention provides a preparation method of the basic mineral substance growth promoter for the chicks, which is characterized in that after the probiotics are activated, the probiotics are mixed with sodium bicarbonate, potassium chloride, yeast zinc, calcium chloride, fructose, honey, corn flour, corn bran, whole wheat flour and water to obtain a mixture, and the mixture is fermented to obtain the basic mineral substance growth promoter for the chicks.
Preferably, the fermentation is carried out under the light-shielding condition, the fermentation comprises a first fermentation and a second fermentation which are sequentially carried out, the temperature of the first fermentation is 30-40 ℃, the time of the first fermentation is 3-4 d, the temperature of the second fermentation is 45-65 ℃, and the time of the second fermentation is 3-4 d.
Preferably, the water content of the mixture is 30 to 40wt%.
Preferably, the activation of the probiotics is that the probiotics are mixed with water and then cultured for 0.5 to 1 hour at the temperature of between 34 and 37 ℃.
The invention provides the chick alkaline mineral substance growth promoter disclosed by the technical scheme or the application of the chick alkaline mineral substance growth promoter prepared by the chick alkaline mineral substance growth promoter preparation method disclosed by the technical scheme in one or more of (1) to (3):
(1) The production performance of the chicks is improved;
(2) Reducing the feed-meat ratio of the chicks;
(3) Improving the content of the duodenal immune substance of the chicks; the immune material includes one or more of complement C3, complement C4, igG, igM, and SIgA.
The invention provides the chick alkaline mineral substance growth promoter according to the technical scheme or the application method of the chick alkaline mineral substance growth promoter prepared by the preparation method of the chick alkaline mineral substance growth promoter according to the technical scheme, and the chick alkaline mineral substance growth promoter is mixed with water and then fed to the chick.
Preferably, the feeding mass concentration of the basic mineral substance growth promoter for the chicks is 0.025% -0.5%.
The invention has the beneficial effects that: the invention provides a chick alkaline mineral substance growth promoter which comprises the following components in parts by mass: potassium chloride, sodium bicarbonate, yeast zinc, calcium chloride, fructose, honey, corn flour, corn bran, whole wheat flour and probiotics. The alkaline mineral composition compound of sodium bicarbonate, yeast zinc and calcium chloride in the alkaline mineral growth promoter for the chicks can supplement minerals, generate important biological compounds such as hormone and enzyme, promote the bone formation of the chicks, promote the chicks to grow, and can not generate toxic and side effects and drug resistance. The chicks have weak disease resistance and stress resistance, and can effectively balance electrolyte after being supplemented with alkaline mineral ions, so that stress hazard is reduced. And the alkaline mineral ions can also inhibit the growth of bacteria and moulds, resist the invasion of viruses, strengthen the barrier function, reduce inflammatory reaction and improve the immunity of chickens. Higher nutrient intake in large-scale farming may lead to metabolic disorders caused by increased organic acid production, while basic mineral ions may promote metabolic balance by alleviating increased organic acid production and increase the feed acceptance of chickens. In addition, the invention uses corn flour, corn bran, whole wheat flour, natural sugar fructose and honey as fermentation carriers, and the alkaline mineral substance growth promoter obtained by fermenting probiotics has the effects of improving intestinal morphology, optimizing gastrointestinal microbial structure, being beneficial to digestion and absorption, solving the problems of incomplete development of the digestive system and dyspepsia caused by weak digestion capacity of the chicks, improving the taste of the alkaline mineral substance growth promoter and providing energy for the chicks. The results of the examples show that: the chick alkaline mineral substance growth promoter can obviously increase the weight of the chick, reduce the feed-to-meat ratio, enhance the immunity and improve the intestinal health when the chick is fed with water, thereby improving the production performance of the chick.
Compared with the alkaline mineral substance growth promoting agent in the prior art, the alkaline mineral substance growth promoting agent for the chicks has the following advantages: (1) The chick alkaline mineral substance growth promoter is low in price, high in efficiency, organic and nontoxic; (2) Can supplement various mineral substances and effectively balance electrolyte; (3) Antibacterial and antiviral, effectively improves the immunity and the anti-stress capability of the chicks, and can be used as an antibiotic to replace the conventional growth promoter in the prior art; (4) maintaining intestinal health and improving feed conversion rate; (5) The addition of a plurality of probiotics effectively optimizes the flora composition, improves the functions of intestinal flora and is beneficial to the absorption of nutrient substances; (6) effectively improving the growth performance of the chicks; and (7) the water drinking mode is adopted, so that the feeding is convenient, and the stress is reduced.
Drawings
In order to more clearly illustrate the embodiments of the present invention or the technical solutions in the prior art, the drawings that are required to be used in the embodiments will be briefly described below.
FIG. 1 is a graph showing the effect of feeding an alkaline mineral complex alkaline mineral growth promoter to example 2-3 and comparative example 1 on chicken intestinal histology; wherein A is duodenal H & E staining (40X); b is quantification of fluff height; c is quantification of duodenal crypt depth; d is the ratio of the duodenal villus height to the crypt depth;
FIG. 2 shows the effect of the basic mineral growth promoter fed with the basic mineral complex of examples 2 to 3 and comparative example 1 on the content of substances related to innate immunity and acquired immunity of chickens.
Detailed Description
The invention provides an alkaline mineral substance growth promoter for chickens, which comprises the following components: the composition comprises the following components: potassium chloride, sodium bicarbonate, yeast zinc, calcium chloride, fructose, honey, corn flour, corn bran, whole wheat flour and probiotics.
The basic mineral substance growth promoter for the chicks provided by the invention preferably comprises the following components in parts by mass: 8 to 12 parts of potassium chloride, 20 to 25 parts of sodium bicarbonate, 0.01 to 0.04 part of yeast zinc, 0.05 to 0.10 part of calcium chloride, 20 to 25 parts of fructose, 15 to 20 parts of honey, 20 to 25 parts of corn flour, 490 to 510 parts of corn bran, 490 to 510 parts of whole wheat flour and 5 to 10 parts of probiotics.
The basic mineral substance growth promoter for the chicks provided by the invention comprises 20-25 parts by mass of sodium bicarbonate, preferably 21-24 parts by mass, and more preferably 22.5 parts by mass.
The basic mineral substance growth promoter for the chicks provided by the invention comprises 8-12 parts of potassium chloride, preferably 9-11 parts of potassium chloride and more preferably 10 parts of potassium chloride based on the mass parts of sodium bicarbonate.
The chick alkaline mineral substance growth promoter provided by the invention comprises 0.01-0.04 part of yeast zinc, preferably 0.02-0.03 part, more preferably 0.025 part by mass of sodium bicarbonate.
Based on the mass parts of sodium bicarbonate, the basic mineral substance growth promoter for the chicks provided by the invention comprises 0.05-0.10 part of calcium chloride, preferably 0.06-0.09 part, and more preferably 0.075 part.
The chick alkaline mineral substance growth promoter provided by the invention comprises 20-25 parts of fructose, preferably 21-24 parts of fructose, and more preferably 22.5 parts of fructose based on the mass parts of sodium bicarbonate.
The basic mineral substance growth promoter for the chicks provided by the invention comprises 15-20 parts of honey, preferably 16-19 parts of honey, and more preferably 17.5 parts of honey based on the mass parts of sodium bicarbonate.
The basic mineral substance growth promoter for the chicks provided by the invention comprises 20-25 parts of corn flour, preferably 21-24 parts of corn flour, and more preferably 22.5 parts of corn flour based on the mass parts of sodium bicarbonate.
The chick alkaline mineral substance growth promoter provided by the invention comprises 490-510 parts of corn bran, preferably 493-508 parts, and more preferably 500 parts by mass of sodium bicarbonate.
The chick alkaline mineral substance growth promoter provided by the invention comprises 490-510 parts of whole wheat flour, preferably 495-505 parts, and more preferably 500 parts by mass of sodium bicarbonate.
Based on the mass parts of sodium bicarbonate, the basic mineral substance growth promoter for the chicks provided by the invention comprises 5-10 parts of probiotics, preferably 6-9 parts, and more preferably 7.4 parts.
The mass ratio of the potassium chloride, the sodium bicarbonate, the yeast zinc, the calcium chloride, the fructose, the honey, the corn flour, the corn bran, the whole wheat flour and the probiotics is preferably 8-12: 20-25: 0.01 to 0.04:0.05 to 0.10: 20-25: 15-20: 20-25: 490-510: 5 to 10, more preferably 9 to 11: 21-24: 0.02 to 0.03:0.06 to 0.09: 21-24: 16-19: 21-24: 495-505: 6 to 9; more preferably 10:22.5:0.025:0.075:22.5:17.5:22.5:500:500:7.4.
recent studies have found that mineral products can be added to animal feed compositions to reduce or replace antibiotics, but that the levels of mineral elements in the currently available mineral products are relatively high, potentially causing toxic effects on animals, such as excessive heavy metal content in the mineral products and determined by the food and drug administration to be toxic to humans and animals. In the invention, the alkaline mineral substances comprise sodium bicarbonate, yeast zinc and calcium chloride, and the alkaline mineral substance compound can supplement mineral substances, generate important biological compounds such as hormone, enzyme and the like, promote the bone formation of the chicks, promote the growth of the chicks, and can not generate toxic or side effect and drug resistance; the supplemented alkaline mineral ions can also effectively balance electrolytes of the chicks, and reduce various stress hazards of the chicks due to feed mildew, frequent immunization programs, cold stress and heat stress. And the alkaline mineral ions can also inhibit the growth of bacteria and moulds, resist the invasion of viruses, strengthen the barrier function, reduce inflammatory reaction and improve the immunity of chickens.
In the present invention, the probiotics preferably include one or more of lactic acid bacteria, yeast, enterococcus faecium and bacillus subtilis, more preferably include lactic acid bacteria, yeast, enterococcus faecium and bacillus subtilis.
In the present invention, when the probiotics preferably include lactobacillus, saccharomycete, enterococcus faecium and bacillus subtilis, the mass parts of the lactobacillus, saccharomycete, enterococcus faecium and bacillus subtilis are preferably 1.25-2.6:1.5-2.8:1.25-2.6:1-2, more preferably 1.5-2.0:1.7-2.5:1.4-2.3:1.2-1.8, and even more preferably 1.8:2.0:2.0:1.6.
The probiotics in the basic mineral substance growth promoter for the chicks provided by the invention preferably comprise 1.25-2.6 parts of lactic acid bacteria, more preferably 1.5-2.0 parts, and even more preferably 1.8 parts by mass.
The probiotics in the basic mineral substance growth promoter for the chicks provided by the invention preferably comprise 1.5-2.8 parts of saccharomycetes, more preferably 1.7-2.5 parts of probiotics, and even more preferably 2.0 parts of probiotics.
The probiotics in the basic mineral substance growth promoter for the chicks provided by the invention preferably comprise 1.25-2.6 parts of enterococcus faecium, more preferably 1.4-2.3 parts of enterococcus faecium, and even more preferably 2.0 parts of enterococcus faecium.
The probiotics in the alkaline mineral substance growth promoter for the chicks provided by the invention preferably comprise 1-2 parts by mass of bacillus subtilis, more preferably 1.2-1.8 parts by mass, and even more preferably 1.6 parts by mass.
The viable count of the lactic acid bacteria is preferably 2 to 3 x 10 10 CFU/g, more preferably 2.5 x 10 10 CFU/g; the viable count of the saccharomycetes is preferably 2 to 2.5 x 10 10 CFU/g, more preferably 2.25 x 10 10 CFU/g; the viable count of the enterococcus faecium is preferably 2 to 2.5 x 10 9 CFU/g, more preferably 2.25 x 10 9 CFU/g, the viable count of the bacillus subtilis is preferably 2-2.5 x 10 10 CFU/g, more preferably 2.5 x 10 10 CFU/g。
The lactobacillus purchase, the saccharomycetes, the enterococcus faecium and the bacillus subtilis are all conventional commercial products. The invention uses corn flour, corn bran, whole wheat flour, natural sugar fructose and honey as fermentation carriers, and the alkaline mineral substance growth promoter prepared by fermenting probiotics is more beneficial to digestion and absorption of chickens, has the functions of probiotics, improves intestinal morphology of chickens, optimizes gastrointestinal microbial structure, is beneficial to digestion and absorption, solves the digestion problem caused by imperfect development of digestive system and weak digestion capacity of chickens, and simultaneously can improve the taste of the alkaline mineral substance growth promoter by adding corn flour, corn bran, whole wheat flour, natural sugar fructose and honey to provide energy for chickens.
The sources of the components in the feed are not particularly limited, as long as they are well known to those skilled in the art.
The invention provides a preparation method of the basic mineral substance growth promoter for the chicks, which is characterized in that after the probiotics are activated, the probiotics are mixed with sodium bicarbonate, potassium chloride, yeast zinc, calcium chloride, fructose, honey, corn flour, corn bran, whole wheat flour and water to obtain a mixture, and the mixture is fermented to obtain the basic mineral substance growth promoter for the chicks.
In the present invention, the probiotic activation is preferably performed by mixing the probiotic with water and then culturing the mixture at 34 to 37℃for 0.5 to 1 hour, more preferably 0.5 hour.
The probiotics of the invention are activated and then mixed with the sodium bicarbonate, potassium chloride, yeast zinc, calcium chloride, fructose, honey, corn flour, corn bran, whole wheat flour and water to obtain a mixture, and the water content of the mixture is preferably 30-40 wt%, more preferably 32-38 wt%, and even more preferably 35wt%. The invention adds water to keep the moisture content when preparing the chicken alkaline mineral substance growth promoter, which is beneficial to the fermentation of probiotics. The mixing parameters are not particularly limited in the invention, and a conventional mixing mode is adopted.
After the mixture is obtained, the mixture is fermented to obtain the basic mineral substance growth promoter for the chicks. In the invention, the fermentation is preferably carried out under the light-shielding condition, so that the light-shielding condition is selected to ensure that the nutritional ingredients of the raw materials are not damaged, and researches show that light has a catalytic effect on the quality change of the feed, the light can cause fat oxidation, the fat-soluble vitamins are damaged, and the protein can also change due to the light.
The fermentation of the present invention preferably comprises a first fermentation and a second fermentation which are sequentially carried out, wherein the temperature of the first fermentation is preferably 30-40 ℃, more preferably 33-38 ℃, and even more preferably 35 ℃; the time of the first fermentation is preferably 3-4 d, more preferably 3.5d; the temperature of the second fermentation is preferably 45-65 ℃, more preferably 50-60 ℃, and even more preferably 58 ℃; the time for the second fermentation is preferably 3 to 4 days, more preferably 3.5 days.
After the chick alkaline mineral substance growth promoter is prepared, the chick alkaline mineral substance growth promoter is preferably stored at room temperature for standby.
The invention provides the chick alkaline mineral substance growth promoter disclosed by the technical scheme or the application of the chick alkaline mineral substance growth promoter prepared by the preparation method of the chick alkaline mineral substance growth promoter disclosed by the technical scheme in one or more actions of (1) to (3).
(1) The production performance of the chicks is improved;
(2) Reducing the feed-meat ratio of the chicks;
(3) Improving the content of the duodenal immune substance of the chicks; the immune material includes one or more of complement C3, complement C4, igG, igM, and SIgA.
The invention provides the chick alkaline mineral substance growth promoter according to the technical scheme or the application method of the chick alkaline mineral substance growth promoter prepared by the preparation method of the chick alkaline mineral substance growth promoter according to the technical scheme, and the chick alkaline mineral substance growth promoter is mixed with water and then fed to the chick.
The source of water is not particularly limited, and the water can be conventionally used as drinking water. The mass concentration of the alkaline mineral substance growth promoter for the chicks is preferably 0.025% -0.5%, more preferably 0.03% -0.4%, and even more preferably 0.25% when the chicks are fed.
Based on the demands of chicken raising industry on low-price, high-efficiency, organic and nontoxic alkaline mineral substance growth promoting agents, the alkaline mineral substance, natural sugar and probiotics are scientifically designed and reasonably combined to prepare the alkaline mineral substance compound alkaline mineral substance growth promoting agent, the technical problem of high cost of organic motor products is solved, and the alkaline mineral substance growth promoting agent can effectively enhance the immunity and the anti-stress capability of organisms, protect intestinal health and promote the growth of chicks.
The basic mineral substance growth promoter for the chicks, which is provided by the invention, is used as a drinking water additive, can be used for symptomatic administration combination according to actual growth conditions and day ages of the chicks, is scientifically and reasonably matched for use, and can be used for optimizing and adjusting use concentration according to different day ages of the chicks and different health states of the chicks, and in one example of the invention, the optimal administration concentration for the chicks of 14 days is 0.25%.
The technical solutions provided by the present invention are described in detail below with reference to the drawings and examples for further illustrating the present invention, but they should not be construed as limiting the scope of the present invention.
EXAMPLE 1 preparation of basic mineral Complex growth-promoting formulation
(1) Activation of composite probiotics: lactic acid bacteria 1.8g, saccharomycete 2g, faeciumGrinding 2g of cocci and 1.6g of bacillus subtilis, mixing with 100mL of water, and activating at 34-37 ℃ for 0.5h to obtain activated composite probiotics. 1.8g lactobacillus viable count is 4.5×10 10 CFU, 2g yeast viable count 4.5×10 10 CFU, 2g enterococcus faecium viable count of 4.5 x 10 9 CFU and 1.6g bacillus subtilis viable count of 4 x 10 10 CFU。
(2) Uniformly mixing the activated composite probiotic liquid in the step (1) with 10g of potassium chloride, 22.5g of sodium bicarbonate, 0.025g of yeast zinc, 0.075g of calcium chloride, 22.5g of fructose, 17.5g of honey, 22.5g of corn flour, 500g of corn bran, 500g of whole wheat flour and a proper amount of water, and controlling the water content to be 35wt% after mixing; fermenting at 37deg.C for 4 days in dark place, fermenting at 55deg.C for 3 days in dark place to obtain alkaline mineral substance growth promoter, and storing at room temperature for use.
Example 2
The basic mineral growth promoter prepared in example 1 was fed.
Animal feeding tests were performed at 29 days 4 in 2021 to 10 days 6 in 2021. The test animals are 20 chicks with 14 days of age and similar weight. Example 2 an alkaline mineral growth promoter solution was given at a mass concentration of 0.25% at a feeding ambient temperature of 25 c for 12h light and 12h dark. The alkaline mineral growth promoter solution was freely ingested and drunk during the test without separate feeding of water. The chick basic ration is purchased from Zhengda feed limited company, and the specific components and proportions are shown in table 1-1:
TABLE 1-1 ration composition
Example 3
The test animals are 20 chicks with similar weight at 14 days of age, and are fed with an alkaline mineral substance growth promoter solution with the mass concentration of 0.5%, and the rest feeding conditions are kept the same as in example 2.
Comparative example 1
The test animals were 20 chicks of 14 days of age and similar weight, and comparative example 1 was fed sterile water without any treatment, and the other conditions were the same as example 2.
The initial weights of the chicks of examples 2 to 3 and comparative example 1 were not significantly different, and the test period of examples 2 to 3 and comparative example 1 was 6 weeks. The chicks of examples 2 to 3 and comparative example 1 were observed for mental status, nutritional status, posture and exercise, and physiological activities. The weight of the chicks was weighed before the start of the test and recorded as W0, the chicks of examples 2 to 3 and comparative example 1 were weighed weekly for the first week (W1) to the sixth week (W6), the average feed intake of the chicks of group 1 of comparative example 1 was 1512.1g, the average feed intake of the chicks of group 2 was 1516.2g, the average feed intake of the chicks of group 3 was 1513.7g, and the weekly weight gain and feed/meat ratio were calculated for evaluating the effect of the basic mineral complex growth-promoting preparation on the growth performance of the chicks. After 3 and 6 weeks of conventional feeding, serum and intestinal tissues were collected for storage and treatment. After the 3 rd week of feeding is finished, serum and intestinal tissues of 10 chickens are collected from each group, and the rest 10 chickens in each group are fed continuously. The specific method for collecting serum and intestinal tissues for preservation and treatment is as follows:
serum was collected: the chicks were treated with carbon dioxide to exclude the effect of stress factors on the test. After neck-breaking blood sampling, the blood was placed in a 37℃incubator for 1h,2500g was centrifuged for 5min, and the supernatant was stored in a-80℃refrigerator.
Collecting intestinal tissues: after the chick is subjected to neck breakage and blood sampling, quickly collecting duodenal tissues on an ice bag, cutting into intestinal section tissue blocks with the length of 0.5cm, soaking in 4% paraformaldehyde solution, performing HE dyeing and scanning electron microscope observation, measuring the height of villus, the depth of crypt, and the ratio of the height of villus to the depth of crypt, and evaluating the protection effect of the alkaline mineral substance growth promoting agent of the alkaline mineral substance compound on the physical barrier of the chick intestinal canal.
Immune substance detection: a portion of duodenal tissue was taken and examined for the effects of complement C3, complement C4, immunoglobulin M (IgM), immunoglobulin G (IgG) and secreted immunoglobulin A (SIgA) levels for the basic mineral complex basic mineral growth-promoting agent on chicken immune function. IgM, igG and sIgA in the duodenum of the chick were measured using a chicken immunoglobulin M (IgM) ELISA kit, a chicken immunoglobulin G (IgG) ELISA kit and a chicken secretory immunoglobulin A (SIgA) ELISA kit, respectively, and a chicken complement C3 kit, a chicken complement C4 kit, a chicken immunoglobulin G (IgG) ELISA kit, a chicken immunoglobulin M (SIgM) ELISA kit, and a chicken secretory immunoglobulin A (SIgA) ELISA kit were purchased from Jiangsu enzyme immune industry Co., ltd (purchase website: http:// www.mmbio.cn /). The content was calculated by measuring OD at 450nm, which was performed exactly as described.
Clinical observation shows that the chicks in the group 1 of the comparative example have good mental condition, normal drinking water, and no abnormality in posture, movement and physiological activity. The chickens in the examples 2-3 have good statue, contend for eating during feeding, have flexible movement, do not gather and pile, have low head and neck shrinkage and are in a fizzing condition, and each group of chickens presents a healthy and active state.
The weights of the group 1 chicks of examples 2 to 3 and comparative example 1 are shown in Table 1. As can be seen from table 1, the chicks of example 2 significantly increased in weight (P <0.05, P <0.01, or P < 0.001) 3 to 6 weeks after supplementation with the alkaline mineral compound alkaline mineral growth promoter, as compared to comparative example 1; chicks of example 3 had significantly increased body weight (P <0.05 or P < 0.001) 3 to 4 weeks after supplementation with the alkaline mineral complex alkaline mineral growth promoter. In table 1, the number of samples per group of chicken of W0 was 14, the number of samples per group of chicken of W1, W2, W3 was 14, and the number of samples per group of chicken of W4, W5, W6 was 7.
Table 1 weight (g) of group 1 chicks of examples 2 to 3 and comparative example 1
Note that: significant differences between the treatment groups of examples 2-3 and comparative example 1 are expressed as a.
Average weekly weights of the group of chicks of examples 2 to 3 and comparative example 1 are shown in table 2, and the average weekly weight weights of example 2 always have an increasing trend after the addition of the alkaline mineral growth promoter compared with comparative example 1, and have remarkable effects on weeks 2, 4 and 6 (P <0.05 or P < 0.001); example 3 showed a significant increase in average weekly weight gain at weeks 2 and 3 (P <0.05 or P < 0.001) compared to comparative example 1. In table 2, the number of samples per group of chicken of W1, W2, W3 was 14, and the number of samples per group of chicken of W4, W5, W6 was 7.
Table 2 average weekly weight gain (g) of chicks of examples 2-3 and comparative example 1
Note that: significant differences between comparative example 1 and examples 2-3 are expressed by x; the significance of the difference between example 2 and example 3 was used # And (3) representing. * P (P)<0.05，**P<0.01，***P<0.001；#P<0.05，##P<0.01，###P<0.001。
Basic mineral complexes the effect of basic mineral growth promoters on total weight gain of chickens is shown in table 3. The calculation formula of the total weight gain is as follows: total weight gain of chicks = difference in chick weight at the end of week 6 of feeding versus chick weight before starting feeding.
The total weight gain of example 2 was significantly increased (P < 0.01) and the total weight gain of example 3 showed an increasing trend after supplementation with the alkaline mineral compound alkaline mineral growth promoter compared to comparative example 1. In table 3, the number of samples of each group of chicks of examples 2 to 3 and comparative example 1 was 7 when total weight gain of the chicks was calculated.
TABLE 3 Total weight gain (g) for chicks of examples 2-3 and comparative example 1
Note that: significant differences are expressed in x (P < 0.05). * P <0.05, < P <0.01, < P <0.001.
The chicken feed meat ratio was calculated as follows:
feed ratio = total feed consumed (kg)/total weight gain (kg).
The chicken feed of examples 2 to 3 and comparative example 1 are shown in table 4. The decreased feed to meat ratio of examples 2 and 3 after supplementing the alkaline mineral complex alkaline mineral growth promoter compared to comparative example 1 demonstrates that supplementing the alkaline mineral complex alkaline mineral growth promoter increases the ability of the chicks to convert to feed. In table 4, the number of samples of each group of chicks of examples 2 to 3 and comparative example 1 was 7 when the chick feed/meat ratio was calculated.
Table 4 chick feed to meat ratios of examples 2 to 3 and comparative example 1
Note that: significant differences are expressed in x. * P <0.01.
Basic mineral Complex the effect of basic mineral growth promoters on the intestinal tissue morphology of chicks of examples 2-3 and comparative example 1 is shown in FIG. 1. The results of the intestinal HE stained sections (a in fig. 1) showed that each group of duodenal mucosa, submucosa, myolayer and serosa was complete, the small intestinal mucosa extended into the lumen of the intestine with small intestinal glands in the lamina propria, opening into the intestinal villi, and no apparent lesions were seen. After supplementation with the alkaline mineral complex alkaline mineral growth promoter, the chick pile heights of example 2 and example 3 were significantly increased (P <0.01 or P <0.001, B in fig. 1) compared to comparative example 1; example 2 and example 3 chick crypt depth was significantly reduced (P <0.01 or P <0.001, C in fig. 1); both example 2 and example 3 chicks had significantly elevated duodenal villus height to crypt depth ratios (P <0.01 or P <0.001, D in fig. 1). It can be seen that feeding the alkaline mineral compound with the alkaline mineral growth promoter increases the duodenal villus height to crypt depth ratio of the chick, increases intestinal villus absorption area, and increases nutrient absorption.
TABLE 5 intestinal tissue morphology results for chicks of examples 2-3 and comparative example 1
The effect of alkaline mineral complex alkaline mineral growth promoters on the content of innate and acquired immune substances in the chicks of examples 2 to 3 and comparative example 1 as shown in fig. 2, the chicks after supplementation with the alkaline mineral complex alkaline mineral growth promoters had elevated levels of native immune substances (complement C3 and complement C4) and acquired immune related substances (IgG, igM and SIgA) (P <0.01 or P < 0.001). The alkaline mineral compound is supplemented with an alkaline mineral growth promoter, which can promote the growth and immunity of chickens.
TABLE 6 content of innate and acquired immune substances in chicks of examples 2 to 3 and comparative example 1
In conclusion, the alkaline mineral substance growth promoter for the chicks provided by the invention can obviously increase the weight of the chicks, reduce the feed-to-meat ratio, enhance the immunity and improve the intestinal health, thereby improving the production performance of the chicks.
Although the foregoing embodiments have been described in some, but not all, embodiments of the invention, it should be understood that other embodiments may be devised in accordance with the present embodiments without departing from the spirit and scope of the invention.
Claims (10)
1. An alkaline mineral growth promoter for chickens, which is characterized by comprising the following components: potassium chloride, sodium bicarbonate, yeast zinc, calcium chloride, fructose, honey, corn flour, corn bran, whole wheat flour and probiotics.
2. The alkaline mineral substance growth-promoting agent for chicks according to claim 1, comprising the following components in parts by mass: 8 to 12 parts of potassium chloride, 20 to 25 parts of sodium bicarbonate, 0.01 to 0.04 part of yeast zinc, 0.05 to 0.10 part of calcium chloride, 20 to 25 parts of fructose, 15 to 20 parts of honey, 20 to 25 parts of corn flour, 490 to 510 parts of corn bran, 490 to 510 parts of whole wheat flour and 5 to 10 parts of probiotics.
3. According to claim 1Or 2, wherein the probiotics comprise one or more of lactobacillus, saccharomycete, enterococcus faecium and bacillus subtilis; when the probiotics comprise lactobacillus, saccharomycete, enterococcus faecium and bacillus subtilis, the mass ratio of the lactobacillus, the saccharomycete, the enterococcus faecium and the bacillus subtilis is 1.25-2.6:1.5-2.8:1.25-2.6:1-2; the viable count of the lactic acid bacteria is 2-3 x 10 10 CFU/g, the viable count of the saccharomycetes is 2-2.5 x 10 10 CFU/g, the viable count of the enterococcus faecium is 2-2.5 x 10 9 CFU/g, the viable count of the bacillus subtilis is 2-2.5 x 10 10 CFU/g。
4. A method for preparing the alkaline mineral growth-promoting agent for chicks according to any one of claims 1 to 3, wherein the probiotic is mixed with sodium bicarbonate, potassium chloride, yeast zinc, calcium chloride, fructose, honey, corn flour, corn bran, whole wheat flour and water after being activated to obtain a mixture, and the mixture is fermented to obtain the alkaline mineral growth-promoting agent for chicks.
5. The method according to claim 4, wherein the fermentation is carried out under a dark condition, the fermentation comprises a first fermentation and a second fermentation which are sequentially carried out, the temperature of the first fermentation is 30-40 ℃, the time of the first fermentation is 3-4 d, the temperature of the second fermentation is 45-65 ℃, and the time of the second fermentation is 3-4 d.
6. The method according to claim 4, wherein the water content of the mixture is 30 to 40wt%.
7. The method according to claim 4, wherein the probiotic bacteria are mixed with water and cultured at 34-37 ℃ for 0.5-1 h.
8. The use of the basic mineral growth-promoting agent for chickens according to any one of claims 1 to 3 or the basic mineral growth-promoting agent for chickens according to any one of claims 4 to 7 in one or more of (1) to (3):
(1) The production performance of the chicks is improved;
(2) Reducing the feed-meat ratio of the chicks;
(3) Improving the content of the duodenal immune substance of the chicks; the immune material includes one or more of complement C3, complement C4, igG, igM, and SIgA.
9. The method for using the basic mineral growth-promoting agent for chicks prepared by the basic mineral growth-promoting agent for chicks according to any one of claims 1 to 3 or the method for preparing the basic mineral growth-promoting agent for chicks according to any one of claims 4 to 7, characterized in that the basic mineral growth-promoting agent for chicks is mixed with water and then fed to chicks.
10. The use method according to claim 9, wherein the feeding mass concentration of the basic mineral substance growth-promoting agent for the chicks is 0.025% -0.5%.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202310035816.7A CN116138364A (en) | 2023-01-10 | 2023-01-10 | Basic mineral substance growth promoter for chicks, and preparation method, application and use method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202310035816.7A CN116138364A (en) | 2023-01-10 | 2023-01-10 | Basic mineral substance growth promoter for chicks, and preparation method, application and use method thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN116138364A true CN116138364A (en) | 2023-05-23 |
Family
ID=86359465
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202310035816.7A Pending CN116138364A (en) | 2023-01-10 | 2023-01-10 | Basic mineral substance growth promoter for chicks, and preparation method, application and use method thereof |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN116138364A (en) |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103039738A (en) * | 2012-12-19 | 2013-04-17 | 山东蔚蓝生物科技有限公司 | Compound diet formula for chicks |
| CN107629981A (en) * | 2017-10-13 | 2018-01-26 | 安徽农业大学 | A kind of compound probiotic agent for improving chick function of intestinal canal and preparation method thereof |
-
2023
- 2023-01-10 CN CN202310035816.7A patent/CN116138364A/en active Pending
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103039738A (en) * | 2012-12-19 | 2013-04-17 | 山东蔚蓝生物科技有限公司 | Compound diet formula for chicks |
| CN107629981A (en) * | 2017-10-13 | 2018-01-26 | 安徽农业大学 | A kind of compound probiotic agent for improving chick function of intestinal canal and preparation method thereof |
Non-Patent Citations (1)
| Title |
|---|
| 汤怡曦: "碱性矿物质复合物对雏鸡肠道健康影响的研究", 硕士论文, 23 November 2022 (2022-11-23), pages 5 - 6 * |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN106834163A (en) | Feed fermentation agent, fermented feed and preparation method thereof | |
| KR101296837B1 (en) | manufacturing method of fermented feed with tangerine and treber | |
| CN107549456B (en) | A kind of compound probiotic agent and preparation method thereof improving goose function of intestinal canal | |
| WO2011115306A1 (en) | Feed-use-efficiency improver for ruminant animals | |
| CN104522433A (en) | Laying hen compound biological feed additive and preparation method thereof | |
| KR20210043877A (en) | Method for preparing fermented total mixed ration using microbial strain complex | |
| KR101059672B1 (en) | Duck breeding method capable of spawning duck eggs containing sulfur and duck eggs produced by the breeding method | |
| CN102084937B (en) | Fodder acidulant and application method thereof | |
| RU2350101C2 (en) | "lacto-plus" farm animal fodder additive | |
| CN112075546A (en) | Feed additive for improving oxygen-gaining capability of poultry and application thereof | |
| CN109770060A (en) | A method of preparing soybean stalk feed | |
| CN102630844A (en) | Preparation method of biological feed for ruminants | |
| CN101637219B (en) | Biological additive for animal feed and method for preparing same | |
| KR100876521B1 (en) | A probiotics for fermenting mixed rations and a method for fermenting the mixed rations using the probiotics | |
| CN108056260A (en) | Feed for beef cattle and preparation method thereof and the application in the special cultivation of Muslim beef | |
| CN107629981B (en) | A kind of compound probiotic agent and preparation method thereof improving chick function of intestinal canal | |
| CN104886391A (en) | Biological fermentation feed for reducing odor of pig manure and preparation method of biological fermentation feed | |
| CN100475952C (en) | Preparation of feeding live bacterial acid, and dedicated bacterial strain | |
| CN107319199A (en) | A kind of batch for neat mouth schizothoracin | |
| US20210177028A1 (en) | Improved human food product | |
| CN116138364A (en) | Basic mineral substance growth promoter for chicks, and preparation method, application and use method thereof | |
| CN108740497A (en) | A kind of feed addictive and preparation method thereof improving laying hen intestinal health state | |
| JP2021153543A (en) | Feed made from waste creamer | |
| CN112741213A (en) | Preparation method of insect protein source biological feed | |
| CN105284735A (en) | Method for feeding drug residue-free Wenshang Luhua cock at age of 6-18 weeks |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination |