CN116115728A - 一种治疗口腔溃疡的中药组合物及使用方法 - Google Patents
一种治疗口腔溃疡的中药组合物及使用方法 Download PDFInfo
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Abstract
本发明公开了一种治疗口腔溃疡的中药组合物及使用方法，属于中医药技术领域，具体技术方案为：中药组合物的具体组分按照重量份配比如下：甘草13‑17份，冰片1份，干姜2‑5份，黄柏5‑8份，金银花5‑8份，蒲公英8‑10份；中药组合物的具体使用方法为：取中药混合物并加入水，中药混合物与水的重量比为1:5‑1:15，浸泡1‑3小时，对混合液进行过滤并得滤液，在滤液中加入壳聚糖成膜剂，充分溶解，将溶解后的混合液喷至口腔溃疡处，该中药组合物在治疗急性口腔溃疡、慢性口腔溃疡以及过敏性口腔溃疡方面具有很好的治疗效果。
Description
技术领域
本发明属于中医药技术领域，具体涉及一种治疗口腔溃疡的中药组合物及使用方法。
背景技术
口腔溃疡，又称为“口疮”，是发生在口腔粘膜上的表浅性溃疡，大小可从米粒至黄豆大小、成圆形或卵园形，溃疡面为四、周围充血。溃疡具有周期性、复发性及自限性等特点，好发于唇、颊、舌缘等。近年以来，有学者调查显示，我国口腔溃疡疾病患者呈明显的上升趋势，并具重症溃疡患者比例很高，因此，口腔溃疡发病率在口腔疾病中比重较大，位居第三位。人群普遍易感，以中青年最多见，无明显季节性，患病率超过89%。现有的治疗口腔溃疡的药物中，中药制剂普遍存在起效慢、治愈时间长、无法真正愈合的问题。
发明内容
为解决现有技术存在的口腔溃疡临床治疗药物不足的技术问题，本发明提供了一种治疗口腔溃疡的中药组合物，该中药组合物在治疗急性口腔溃疡、慢性口腔溃疡以及过敏性口腔溃疡方面具有很好的治疗效果。
本发明还提供了一种治疗口腔溃疡的中药组合物的使用方法，将药物喷至口腔溃疡处，对口腔溃疡起到良好的治疗效果。
为实现上述目的，本发明所采用的技术方案为：一种治疗口腔溃疡的中药组合物，具体组分按照重量份配比如下：甘草13-17份，冰片1份，干姜2-5份，黄柏5-8份，金银花5-8份，蒲公英8-10份。
一种治疗口腔溃疡的中药组合物的使用方法，包括以下步骤：取中药混合物并加入水，中药混合物与水的重量比为1:5-1:15，浸泡1-3小时，对混合液进行过滤并得滤液，在滤液中加入壳聚糖成膜剂，充分溶解，将溶解后的混合液喷至口腔溃疡处。
甘草是蝶形花科甘草属植物，是一种补益中草药，含黄酮类化合物甘草甙，甘草甙元，异甘草甙，异甘草甙元及甘草利酮，芒柄黄花素，甘草素，异甘草素，树脂等。其中，异甘草甙是其抗溃疡的主要成分。数据显示，异甘草甙是当今治疗溃疡的主要成分之一，而其主要来源于甘草。甘草还可以泻心火，有清热解毒的作用，现代医药学已经证实，甘草有较好的解毒功能，还能抑制胃酸分泌，适量食用甘草，对胃肠道溃疡病也有一定的预防和改善作用。
冰片为龙脑香料植物龙脑香树的树脂中析出的天然结晶性化合物，人工合成的机制冰片，以及艾纳香蒸馏结晶的加工品。冰片具有止痛防腐、开窍醒神、清热生肌等功效。口腔溃疡患者感到不适的症状当中，以溃面疼痛为主，而冰片含有左旋龙脑和右旋龙脑，左旋龙脑可快速止痛，其次还可以有效的清热、止痒、生肌，其主治症状涵盖了口腔溃疡症状的大部分，可在有效短时间内见效，使患者痛感减轻，对饮食、讲话的不适感减轻。
黄柏是中药中清热燥湿药的一种，为芸香科植物，一般常常用来清热、泻火、燥湿、解毒。
金银花具有清热解毒，疏散风热的功效，主治痈肿疔疮，外感风热，温病初起，热毒血痢。
蒲公英具有清热解毒，消肿散结，利湿通淋的功效，主治痈肿疔毒，乳痈内痈，热淋涩痛，湿热黄疸，清肝明目。
采用壳聚糖，壳聚糖具有生物降解性、细胞亲和性和生物效应等许多独特的性质，尤其是含有游离氨基的壳聚糖，是天然多糖中唯一的碱性多糖。壳聚糖分子结构中的氨基基团比甲壳素分子中的乙酰氨基基团反应活性更强，使得该多糖具有优异的生物学功能并能进行化学修饰反应。因此，壳聚糖被认为是比纤维素具有更大应用潜力的功能性生物材料。溶解后的壳聚糖呈凝胶状态，具有较强的吸附能力。壳聚糖中含有羟基、氨基等极性基团，吸湿性很强，甲壳素的吸湿率可达400%-500%，是纤维素的两倍多，壳聚糖的吸湿性比甲壳素更强，可以用作化妆品的保湿剂。壳聚糖游离氨基的邻位为羟基，有螯合二价金属离子的作用，壳聚糖可以螯合重金属离子，作为体内重金属离子的排泄剂，是高性能的金属离子捕集剂。壳聚糖在水中长期放置会发生水解，葡萄糖环开环。壳聚糖因为具有游离氨基可以被开发作为抗原、抗体、酶等生理活性物质的固定化载体。壳聚糖由于物理、化学及生物性能良好，对有机溶剂稳定性极好，方便进行二次加工，所以壳聚糖在食品、造纸、印染、环境保护、纺织、水处理、重金属回收等方面尤其是医疗方面应用前景广阔。
本发明公开的中药组合物，采用多种中草药为原料，其特定的质量比对治疗口腔溃疡有很好的治疗效果，治愈时间短并无副作用。
实施方式
为了使本发明所要解决的技术问题、技术方案及有益效果更加清楚明白，以下结合实施例，对本发明进行进一步详细说明。应当理解，此处所描述的具体实施例仅仅用以解释本发明，并不用于限定本发明。
实施例
一种治疗口腔溃疡的中药组合物，具体组分按照重量份配比如下：甘草13份，冰片1份，干姜2份，黄柏5份，金银花5份，蒲公英8份。
一种治疗口腔溃疡的中药组合物的使用方法，包括以下步骤：取中药混合物并加入水，中药混合物与水的重量比为1:5，浸泡1小时，对混合液进行过滤并得滤液，在滤液中加入壳聚糖成膜剂，充分溶解，将溶解后的混合液喷至口腔溃疡处。
实施例
一种治疗口腔溃疡的中药组合物，具体组分按照重量份配比如下：甘草17份，冰片1份，干姜5份，黄柏8份，金银花8份，蒲公英10份。
一种治疗口腔溃疡的中药组合物的使用方法，包括以下步骤：取中药混合物并加入水，中药混合物与水的重量比为1:15，浸泡3小时，对混合液进行过滤并得滤液，在滤液中加入壳聚糖成膜剂，充分溶解，将溶解后的混合液喷至口腔溃疡处。
实施例
一种治疗口腔溃疡的中药组合物，具体组分按照重量份配比如下：甘草15份，冰片1份，干姜3份，黄柏6份，金银花6份，蒲公英9份。
一种治疗口腔溃疡的中药组合物的使用方法，包括以下步骤：取中药混合物并加入水，中药混合物与水的重量比为1:10，浸泡2小时，对混合液进行过滤并得滤液，在滤液中加入壳聚糖成膜剂，充分溶解，将溶解后的混合液喷至口腔溃疡处。
实施例
一种治疗口腔溃疡的中药组合物，具体组分按照重量份配比如下：甘草14份，冰片1份，干姜4份，黄柏7份，金银花7份，蒲公英8.5份。
一种治疗口腔溃疡的中药组合物的使用方法，包括以下步骤：取中药混合物并加入水，中药混合物与水的重量比为1:12，浸泡1.5小时，对混合液进行过滤并得滤液，在滤液中加入壳聚糖成膜剂，充分溶解，将溶解后的混合液喷至口腔溃疡处。
以上所述仅为本发明的较佳实施例而已，并不用以限制本发明，凡在本发明的精神和原则之内所作的任何修改、等同替换和改进等，均应包在本发明范围内。
Claims (2)
1.一种治疗口腔溃疡的中药组合物，其特征在于，具体组分按照重量份配比如下：甘草13-17份，冰片1份，干姜2-5份，黄柏5-8份，金银花5-8份，蒲公英8-10份。
2.一种治疗口腔溃疡的中药组合物的使用方法，其特征在于，包括以下步骤：取中药混合物并加入水，中药混合物与水的重量比为1:5-1:15，浸泡1-3小时，对混合液进行过滤并得滤液，在滤液中加入壳聚糖成膜剂，充分溶解，将溶解后的混合液喷至口腔溃疡处。
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| CN1919268A (zh) * | 2006-08-19 | 2007-02-28 | 袁爱仙 | 一种治疗口腔溃疡的漱口药物及制备方法 |
| CN101590218A (zh) * | 2009-06-24 | 2009-12-02 | 广州固志医药科技有限公司 | 一种治疗复发性口腔溃疡的中药组合物及其制备方法 |
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| CN1919268A (zh) * | 2006-08-19 | 2007-02-28 | 袁爱仙 | 一种治疗口腔溃疡的漱口药物及制备方法 |
| CN101590218A (zh) * | 2009-06-24 | 2009-12-02 | 广州固志医药科技有限公司 | 一种治疗复发性口腔溃疡的中药组合物及其制备方法 |
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