CN1161136C - Konjaku capsule for treating type-II diabetes - Google Patents
Konjaku capsule for treating type-II diabetes Download PDFInfo
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- CN1161136C CN1161136C CNB011084855A CN01108485A CN1161136C CN 1161136 C CN1161136 C CN 1161136C CN B011084855 A CNB011084855 A CN B011084855A CN 01108485 A CN01108485 A CN 01108485A CN 1161136 C CN1161136 C CN 1161136C
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Abstract
The present invention relates to a Konjaku capsule for treating II type diabetes, which uses natural plants such as Konjaku, American ginseng, astragalus root, red sage root, saffron, leech and cassia twig as raw materials. The raw materials are made into an oral medicine through a reasonable formula. The present invention integrates the unique efficiency of each medicine and has the functions of activating blood circulation to dissipate blood stasis, dredging meridians and channels, reducing blood fat and blood sugar, etc. The present invention can activate the activity of pancreatic beta cells, promote the secretion of insulin, increase the volumes of stomachs and intestines and reduce the absorption of glucose in intestinal tracts. Therefore, the present invention is an ideal medicine for treating diabetes.
Description
The present invention relates to a kind of herbal mixture for the treatment of type ii diabetes--konjaku capsule.
Diabetes are a kind of common worldwide frequently-occurring diseases.It is caused by the excretory insufficient insulin of human body self.And the effect of insulin is the metabolism of regulating sugar in the human body, promptly promotes blood glucose (glucose in the blood) to synthesize glycogen, quickens blood glucose and decomposes blood sugar lowering concentration.When in the human body during hypoinsulinism, the effect that synthetic glycogen of blood glucose and blood glucose decompose will weaken, thereby causes the metabolism disorder of sugar and other nutrient substance, and causes the many organ lesions of human body whole body thus.Along with the progress of society and the raising of people's living standard, the human life-span is also prolonging, but simultaneously diabetics, especially non-insulin-dependent diabetes mellitus (being type ii diabetes NIDDM) number also with the same being doubled and redoubled all over the world.If at present the drug main insulin injection or the oral antidiabetic drug of treatment diabetes, but, and might bring out the danger of myocardial infarction and cerebrovascular disease to old people Yi Yinqi hypoglycemia.The Rhizoma amorphophalli tuber contains 40% glucomannan.According to the relevant research report of Japan, konjak glucomannan has tangible blood sugar reducing function, can suppress the rising of mouse serum and total cholesterol of liver.Chinese patent CN1108062A discloses a kind of " compound slice food made from Amorphophallus rivieri ", is mainly used in fat-reducing, blood fat reducing.Chinese patent CN1234266A discloses a kind of " medicine for restoring islet cell to cure diabetes ", is made up of Chinese medicines such as Radix Ginseng Rubra, Radix Polygoni Multiflori Preparata, Rhizoma Polygonati, Radix Astragali, Fructus Schisandrae Chinensis, Rhizoma Atractylodis, the Rhizoma Atractylodis Macrocephalae, Semen Litchi, Rhizoma Chuanxiong, Radix Salviae Miltiorrhizae, Rhizoma dioscoreae (parched), Fructus Corni, the Radix Rehmanniae, Radix Bupleuri, Cortex Moutan, Radix Puerariae, Pancreas Sus domestica, carnitine, Semen Cassiae seed, Colla Plastri Testudinis, Fructus Cucurbitae moschatae powder, Radix Et Rhizoma Fagopyri Tatarici powder, Rhizoma amorphophalli powders.
The object of the present invention is to provide a kind of have hypoglycemic, promoting blood circulation, reduction blood viscosity, promotion pancreas and the sanguimotor compound recipe Rhizoma amorphophalli of other organs Chinese medicine, be used for the treatment of type ii diabetes.
The present invention is according to the principle of integration of edible and medicinal herbs, guaranteeing on gastrointestinal volume, the hungry basis that disappears, can make that diabetics is conscious keeps a diet, so that mediation gastrointestinal tract, discharge refuse and harmful substance, alleviate the pancreatic secretion burden, promote secretion of insulin, when improving patients ' life quality, reduce and delay the appearance of complication.
The active component of herbal mixture provided by the invention is made up of following components in part by weight:
Rhizoma amorphophalli powder 20-50 Radix Panacis Quinquefolii 5-2 0
Radix Astragali 10-30 Radix Salviae Miltiorrhizae 15-30
Stigma Croci 5-20 Hirudo 5-15
Ramulus Cinnamomi 10-20.
After the present invention adopts prior art to make powder, make tablet or capsule or other dosage form through polish again.When making tablet or capsule, every (grain) 0.7 gram, each three (grains), every day three times, three months is a course of treatment.
Rhizoma amorphophalli powder in the prescription is a monarch drug, has the effect of blood sugar lowering, blood fat reducing, promotion insulin secretion; Radix Panacis Quinquefolii, the Radix Astragali are ministerial drug, energy YIN nourishing, QI invigorating, promoting the production of body fluid to quench thirst; Radix Salviae Miltiorrhizae, Stigma Croci, Hirudo are adjuvant drug, stimulate the menstrual flow, dissipating blood stasis, effect such as invigorate blood circulation; Ramulus Cinnamomi is messenger drug, has the effect of warming the meridian and promoting blood circulation.
Herbal mixture provided by the invention has following characteristics:
1, with resourceful natural edible plant Rhizoma amorphophalli is primary raw material, allocate the compound recipe Rhizoma amorphophalli Chinese medicine that other plant amedica is made again into, combine the special efficacy that medicine had of respectively distinguishing the flavor of, treatment type ii diabetes effect is obvious, the cure rate height, take for a long time, to nontoxic pair of effect of human body, can eliminate patient's hunger sensation, make the patient reach the deep sleep.
2, can activate pancreatic beta cell, increase the gastrointestinal volume, reduce the absorption of glucose in intestinal, the blood sugar control amount is lived pancreas, improves microcirculation of pancreatic gland, promotes secretion of insulin.
The present invention is divided into treatment group and matched group at random with 100 routine cases, and wherein, 50 examples are organized in treatment, matched group 50 examples.The treatment group adds Rhizoma amorphophalli herbal mixture capsule in former Western medicine glucose-lowering treatment, matched group then continues former Western medicine glucose-lowering treatment, and with the Rhizoma amorphophalli compound capsule, be not three months the course of treatment.Its result shows, the suppression ratio matched group of the blood glucose of treatment group and blood fat more remarkable (seeing Table 1).Hemorheology index has significant difference (seeing Table 2) before and after two groups of treatments.
Blood plasma and blood fat comparison before and after the table 1 liang group treatment (mmol/L, X ± S)
Group example number FHG PBC TC TG LDL-C HDL-C
50 treatments preceding 10.40 ± 1.68 13.32 ± 2.98 6.08 ± 0.68 2.87 ± 1.22 4.06 ± 0.52 0.96 ± 0.28 of treatment group
Treatment back 8.29 ± 1.40
※ ※ △ △10.78 ± 2.56
※ ※ △ △5.02 ± 0.63
※ ※ △ △2.30 ± 1.04
※ △3.28 ± 0.65
※ △1.08 ± 0.39
※ △
Matched group 50 treatments preceding 10.38 ± 1.82 13.40 ± 2.84 6.07 ± 0.69 2.82 ± 1.24 4.09 ± 0.58 0.94 ± 0.30
Treatment back 9.67 ± 1.46
△12.32 ± 2.66
△5.96 ± 0.67 2.62 ± 1.26 3.94 ± 0.60 0.97 ± 0.37
Annotate: with relatively compare ※ P<0.05 ※ ※ P<0.01 after △ P<0.05 △ △ P<0.01 and the treatment of control group before this group treatment
Hemorheology index comparison before and after the table 2 liang group treatment (X ± S)
Treatment group (50) matched group (50)
Index is learned in the blood flow gulf
After controlling before controlling after controlling before controlling
The whole blood viscosity height cuts (80
s-1) 6.28 ± 0.74 5.32 ± 0.71
△6.27 ± 0.74 5.98 ± 0.84
(mpa-s) lowly cut (20
s-1) 14.45 ± 2.82 12.12 ± 2.98
△14.42 ± 2.79 13.92 ± 2.86
Plasma viscosity 1.36 ± 0.24 1.20 ± 0.21
△1.37 ± 0.23 1.34 ± 0.25
(mpa-s)
Packed cell volume
0.46±0.05 0.42±0.03 0.45±0.04 0.46±0.03
(%)
Annotate: with preceding relatively △ P<0.05 of this group treatment
Embodiment 1
After carrying out batch mixing by following proportioning (weight for kilogram), adopt the preparation method of prior art to make powder, make tablet or capsule or pill more as required:
Rhizoma amorphophalli powder 20 Radix Panacis Quinquefoliis 5 Radixs Astragali 30
Radix Salviae Miltiorrhizae 15 Stigma Crocis 20 Hirudos 10
Ramulus Cinnamomi 10.
Embodiment 2
After carrying out batch mixing by following proportioning (weight for kilogram), adopt the preparation method of prior art to make powder, make tablet or capsule or pill more as required:
Rhizoma amorphophalli powder 50 Radix Panacis Quinquefoliis 20 Radixs Astragali 10
Radix Salviae Miltiorrhizae 30 Stigma Crocis 5 Hirudos 15
Ramulus Cinnamomi 20.
Embodiment 3
After carrying out batch mixing by following proportioning (weight for kilogram), adopt the preparation method of prior art to make powder, make tablet or capsule or pill more as required:
Rhizoma amorphophalli powder 35 Radix Panacis Quinquefoliis 10 Radixs Astragali 20
Radix Salviae Miltiorrhizae 25 Stigma Crocis 10 Hirudos 5
Ramulus Cinnamomi 15.
Embodiment 4
After carrying out batch mixing by following proportioning (weight for kilogram), adopt the preparation method of prior art to make powder, make tablet or capsule or pill more as required:
Rhizoma amorphophalli powder 30 Radix Panacis Quinquefoliis 10 Radixs Astragali 15
Radix Salviae Miltiorrhizae 20 Stigma Crocis 10 Hirudos 10
Ramulus Cinnamomi 20.
Claims (1)
1, a kind of Rhizoma amorphophalli herbal mixture for the treatment of type ii diabetes is characterized in that its active component is made up of following components by part by weight.
Rhizoma amorphophalli powder 20-50 Radix Panacis Quinquefolii 5-20
Radix Astragali 10-30 Radix Salviae Miltiorrhizae 15-30
Stigma Croci 5-20 Hirudo 5-15
Ramulus Cinnamomi 10-20.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
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CNB011084855A CN1161136C (en) | 2001-05-29 | 2001-05-29 | Konjaku capsule for treating type-II diabetes |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
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CNB011084855A CN1161136C (en) | 2001-05-29 | 2001-05-29 | Konjaku capsule for treating type-II diabetes |
Publications (2)
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CN1387866A CN1387866A (en) | 2003-01-01 |
CN1161136C true CN1161136C (en) | 2004-08-11 |
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CNB011084855A Expired - Fee Related CN1161136C (en) | 2001-05-29 | 2001-05-29 | Konjaku capsule for treating type-II diabetes |
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Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
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CN100345570C (en) * | 2004-12-04 | 2007-10-31 | 南阳市海达生物技术有限公司 | Health care product for treating intestine duct disease, preparation and use method thereof |
CN101890098B (en) * | 2009-05-21 | 2012-03-14 | 中国中医科学院广安门医院 | Medicament for treating type II diabetic cardiopathy and preparation method thereof |
SG11201810662UA (en) * | 2016-06-01 | 2018-12-28 | Shaochi Hsin | An edible composition for reducing the digestion or absorption of the harmful/toxic substance |
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