CN1211426A - Medicine for treating diabetes - Google Patents
Medicine for treating diabetes Download PDFInfo
- Publication number
- CN1211426A CN1211426A CN 97107119 CN97107119A CN1211426A CN 1211426 A CN1211426 A CN 1211426A CN 97107119 CN97107119 CN 97107119 CN 97107119 A CN97107119 A CN 97107119A CN 1211426 A CN1211426 A CN 1211426A
- Authority
- CN
- China
- Prior art keywords
- radix
- medicine
- parts
- cortex mori
- ginseng
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Landscapes
- Medicines Containing Plant Substances (AREA)
Abstract
A medicine for curing diabetes is prepared from 10 Chinese-medicinal materials such as mulberry bark, wolfberry fruit, prepared rehmannia root, scrophularia root, ginseng, ophiopogon root,etc, and features no toxic by-effect and high effect to reduce sugar.
Description
The present invention relates to a kind of medicine for the treatment of diabetes, especially a kind of is the Chinese patent medicine of feedstock production with Chinese medicine.
For a long time, diabetes are one of pertinacious diseases of serious harm human health always.The gold of China before the Yuan Dynasty in the medical book just relevant for the record of treatment diabetes.For example, just put down in writing the medicine of the treatment diabetes that prepare by following proportioning in " side's of declaring opinion " of golden court: Radix Astragali 20g; Radix Ginseng 12g; Radix Ophiopogonis 12g; Radix Rehmanniae 15g; Radix Rehmanniae Preparata 15g; Cortex Mori 20g; Radix Scrophulariae 15g; Rhizoma Atractylodis 10g; Fructus Lycii 15g; Rhizoma Dioscoreae 11g; Radix Salviae Miltiorrhizae 15g; Fructus Schisandrae Chinensis 12g.Though this medicine has certain hypoglycemic effect, and has no side effect, to the Western medicine of treatment of diabetes effect far away from sulphur urea, biguanide and so on, its P value is usually greater than 0.05, and the P value of sulphur urea, biguanide and so on Western medicine generally can reach 0.01.Therefore, in actual therapeutic, the utilization of sulphur urea, the high Western medicine of biguanides price is general more than above-mentioned Chinese patent medicine.
Yet the greatest problem that sulphur urea, biguanide and insulin and so on Western medicine life-time service exists is that side effect is obvious.For example, sulfaurea drugs for a long time with after diminish liver, kidney and hemocyte; The insulin medicine with producing hyperinsulinemia afterwards, causes microangiopathies for a long time.
In recent years, the improvement of treatment diabetes medicament, development are subjected to the common concern of medical profession, have obtained many achievements.For example, application number is that 96117530.0 Chinese patent application " medicines of treatment diabetes " discloses a kind of pure Chinese medicine with Radix Rehmanniae, pollen, Radix Ophiopogonis, Carapax et Plastrum Testudinis, the Radix Astragali, the Rhizoma Anemarrhenae, Rhizoma Dioscoreae, mountain old man's meat, Radix Ginseng, Radix Scrophulariae, Radix Puerariae, Rhizoma Polygonati Odorati, Herba Dendrobii preparation.According to the application documents introduction, this medication is imitated significantly definite.But the rare Chinese medicine that this explosive component relates to is more, and is even curative effect is better in the practicality, also economical inadequately.
The objective of the invention is to: the problem not ideal enough at above-mentioned Chinese patent medicine curative effect, that the Western medicine side effect is bigger proposes a kind ofly to have no side effect, with low cost and curative effect approaches the treatment diabetes Chinese medicine preparation of Western medicine.
Solution of the present invention is the principle of making up a prescription according to above-mentioned motherland therapeutic treatment diabetes, and the pharmacological research of reference for modern medical science is found out and determined after the principal agent composition of blood sugar lowering.Specifically, medicine of the present invention is made (consumption is a weight portion) by following component:
Cortex Mori 25-35 part Fructus Lycii 10-20 part
Radix Rehmanniae Preparata 10-20 part Radix Scrophulariae 10-20 part
Radix Ginseng 10-20 part 10-20 Radix Ophiopogonis part
Rhizoma Atractylodis 10-20 part Radix Salviae Miltiorrhizae 10-20 part
Rhizoma Dioscoreae 10-20 part Radix Astragali 15-25 part
The preferred weight ratio range of preparation medicine of the present invention is:
Cortex Mori 28-32 part Fructus Lycii 13-17 part
Radix Rehmanniae Preparata 13-17 part Radix Scrophulariae 13-17 part
Radix Ginseng 13-17 part 13-17 Radix Ophiopogonis part
Rhizoma Atractylodis 13-17 part Radix Salviae Miltiorrhizae 13-17 part
Rhizoma Dioscoreae 13-17 part Radix Astragali 18-22 part
The optimum weight proportioning of medicine of the present invention is:
15 parts of 30 portions of Fructus Lyciis of Cortex Mori
15 parts of 15 portions of Radix Scrophulariaes of Radix Rehmanniae Preparata
15 parts of Radix Ginseng 15 parts of Radix Ophiopogonis
15 parts of 15 parts of Radix Salviae Miltiorrhizaes of Rhizoma Atractylodis
20 parts of 15 parts of Radixs Astragali of Rhizoma Dioscoreae
The tradition traditional Chinese medical science is thought, takes from the Cortex Mori sweet in the mouth, cold in nature of Radix et Cortex Mori, and function is an eliminating the pathogens from the lung row water, is applicable to cough due to lung-heat, hemoptysis and the edema of the face, dysuria.Blood sugar reducing function for Cortex Mori is not fully recognized that.Therefore, in the record of relevant treatment such as " side's of declaring opinion " diabetes medicament only with Cortex Mori as common ingredients, proportion all is no more than 12%.And find that by the modern medicine analysis means Cortex Mori contains multiple chromocor derivative, comprises Morusin, cyclomorusin, Morusin, mulberrochromene etc.These chromocor derivatives can delay food in gastrointestinal digestion and absorption, suppress the rising of blood in human body in sugar.Therefore, medicine of the present invention has increased substantially the deal of Cortex Mori, with it as the principal agent composition.
In addition, according to theory of Chinese medical science, the Radix Astragali, ginseng qi-tonifying spleen invigorating, Radix Ophiopogonis, yin nourishing cleared away heart-fire, Fructus Lycii, Radix Rehmanniae Preparata the kidney invigorating and essence nourishing, Radix Scrophulariae promoting the production of body fluid to quench thirst, Rhizoma Dioscoreae, Rhizoma Atractylodis invigorating the spleen and benefiting QI, the Radix Salviae Miltiorrhizae blood circulation promoting and blood stasis dispelling, and the Radix Astragali is joined Rhizoma Dioscoreae, Rhizoma Atractylodis are joined Radix Scrophulariae, monoyin and monoyang, one spleen, one kidney, by above-mentioned component compounding pharmaceutical, can play good assistant hypoglycemic effect, make medicine of the present invention have supplementing QI and nourishing YIN, lung heat clearing nourishing kidney, double effect to invigorate blood circulation.
When preparing medicine of the present invention, get the people earlier and participated in water boil 20-30 minute, again other each component is added, boil and cause boiling, be incubated 20-30 minute and can obtain powder agent medicine.
Clinical application is the result show, medicine of the present invention has following major advantage:
1. adopt pure Chinese medicine preparation, to human body nonhazardous effect, hypoglycemic effect is remarkable, and is suitable with Western medicine;
2. contained famous and precious medicine components is few, with low cost, and low price is more suitable for national conditions;
3. except that blood sugar reducing function, also have supplementing QI and nourishing YIN, lung heat clearing nourishing kidney, double nourishing effects to invigorate blood circulation.
Followingly go out according to formal test report, the result of the test of Kunming kind white mice is fully shown the significant curative effect of medicine of the present invention to the treatment diabetes by the Jiangsu Province Medicine Primary Institute.
Experimental condition and process: the healthy mice of getting 90 18-22g, male female half and half, wherein 10 as blank group, other 80 tail veins give alloxan 100mg/kg (per kilogram water 100mg medicine, as follows separating) 72 hours prediction blood glucose, getting blood sugar increasing is 60 of the above white mice of euglycemia twice, is divided into six groups at random.Give isometric distilled water respectively to these six groups of white mice, 15ml/kg benefit Tianjin oral liquid for decreasing blood sugar, the 100mg/kg insoral, 30g/kg, 15g/kg, 7.5g/kg medicine of the present invention, blank group gives isometric distilled water.Continuous seven days, after last administration, measured blood glucose in one hour, do the t check before and after the administration, the results are shown in Table one.
Table one medicine of the present invention is to white mice blood sugar influence contrast table
| Group | Dosage | Blood glucose before the administration | Blood glucose after the administration | The P value |
| Beneficial Tianjin hypoglycemic group phenformin group medicine group of the present invention medicine group of the present invention medicine group of the present invention is organized in the feedwater of blank group | ?15ml/kg ?100mg/kg ?30mg/kg ?15mg/kg ?7.5mg/kg | ?6.96??1.61 ?22.81?5.36 ?22.89?5.20 ?22.90?4.22 ?23.53?3.95 ?23.28?4.14 ?23.20?4.47 | ?7.09??1.52 ?24.66?4.72 ?20.56?3.20 ?16.87?3.19 ?16.37?2.83 ?19.19?2.11 ?21.72?3.75 | ?p＜0.01 ?p＜0.01 ?p＜0.05 |
Embodiment is as follows:
Make up a prescription by following consumption
15 parts of 30 portions of Fructus Lyciis of Cortex Mori
15 parts of 15 portions of Radix Scrophulariaes of Radix Rehmanniae Preparata
15 parts of Radix Ginseng 15 parts of Radix Ophiopogonis
15 parts of 15 parts of Radix Salviae Miltiorrhizaes of Rhizoma Atractylodis
20 parts of 15 parts of Radixs Astragali of Rhizoma Dioscoreae
Get the people earlier and participated in water boil 25 minutes, again other each component is added, boil and cause boiling, be incubated 25 minutes and can obtain required medicine.
Claims (3)
1. medicine for the treatment of diabetes is characterized in that it is the medicament of being made by the raw material of following weight:
Cortex Mori 25-35 part Fructus Lycii 10-20 part
Radix Rehmanniae Preparata 10-20 part Radix Scrophulariae 10-20 part
Radix Ginseng 10-20 part 10-20 Radix Ophiopogonis part
Rhizoma Atractylodis 10-20 part Radix Salviae Miltiorrhizae 10-20 part
2. the medicine of treatment diabetes according to claim 1, wherein the weight proportion of each raw material is:
Cortex Mori 28-32 part Fructus Lycii 13-17 part
Radix Rehmanniae Preparata 13-17 part Radix Scrophulariae 13-17 part
Radix Ginseng 13-17 part 13-17 Radix Ophiopogonis part
Rhizoma Atractylodis 13-17 part Radix Salviae Miltiorrhizae 13-17 part
Rhizoma Dioscoreae 13-17 part Radix Astragali 18-22 part
3. the medicine of treatment diabetes according to claim 1, wherein the weight proportion of each raw material is:
15 parts of 30 portions of Fructus Lyciis of Cortex Mori
15 parts of 15 portions of Radix Scrophulariaes of Radix Rehmanniae Preparata
15 parts of Radix Ginseng 15 parts of Radix Ophiopogonis
15 parts of 15 parts of Radix Salviae Miltiorrhizaes of Rhizoma Atractylodis
20 parts of 15 parts of Radixs Astragali of Rhizoma Dioscoreae
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 97107119 CN1211426A (en) | 1997-09-12 | 1997-09-12 | Medicine for treating diabetes |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 97107119 CN1211426A (en) | 1997-09-12 | 1997-09-12 | Medicine for treating diabetes |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN1211426A true CN1211426A (en) | 1999-03-24 |
Family
ID=5169304
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN 97107119 Pending CN1211426A (en) | 1997-09-12 | 1997-09-12 | Medicine for treating diabetes |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN1211426A (en) |
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1079264C (en) * | 1999-11-10 | 2002-02-20 | 集安市中医医院 | Hypoglyemic liquid medicine |
| CN100384460C (en) * | 2006-05-24 | 2008-04-30 | 胡春良 | Chinese proprietary medicine for regulating blood sugar and application thereof |
| CN101869663A (en) * | 2010-07-09 | 2010-10-27 | 喇孝瑾 | Chinese medicinal preparation for treating diabetes and preparation method thereof |
| CN101204571B (en) * | 2007-12-19 | 2010-12-01 | 张卫星 | Edible Chinese traditional medicine composite for diabetes mellitus and preparation method thereof |
| CN104498270A (en) * | 2014-11-21 | 2015-04-08 | 黄红霞 | Ginseng-fructus lycii traditional Chinese medicinal health wine and preparation method thereof |
| CN104667042A (en) * | 2015-02-05 | 2015-06-03 | 李念虎 | Qi and yin tonifying preparation for diabetes induced by deficiency of both qi and yin and preparation method thereof |
-
1997
- 1997-09-12 CN CN 97107119 patent/CN1211426A/en active Pending
Cited By (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1079264C (en) * | 1999-11-10 | 2002-02-20 | 集安市中医医院 | Hypoglyemic liquid medicine |
| CN100384460C (en) * | 2006-05-24 | 2008-04-30 | 胡春良 | Chinese proprietary medicine for regulating blood sugar and application thereof |
| CN101204571B (en) * | 2007-12-19 | 2010-12-01 | 张卫星 | Edible Chinese traditional medicine composite for diabetes mellitus and preparation method thereof |
| CN101869663A (en) * | 2010-07-09 | 2010-10-27 | 喇孝瑾 | Chinese medicinal preparation for treating diabetes and preparation method thereof |
| CN101869663B (en) * | 2010-07-09 | 2011-11-09 | 河北联合大学 | Chinese medicinal preparation for treating diabetes and preparation method thereof |
| CN104498270A (en) * | 2014-11-21 | 2015-04-08 | 黄红霞 | Ginseng-fructus lycii traditional Chinese medicinal health wine and preparation method thereof |
| CN104667042A (en) * | 2015-02-05 | 2015-06-03 | 李念虎 | Qi and yin tonifying preparation for diabetes induced by deficiency of both qi and yin and preparation method thereof |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN105456622A (en) | Traditional Chinese medicine composition and preparation for treating impaired glucose regulation and preparation method thereof | |
| CN1965953A (en) | Compound medicinal granule capable of tonifying kidney and replenishing qi and method for preparing same | |
| CN1274233C (en) | Siberian solomonseal rhizome medicinal tea and its preparation | |
| CN1565516A (en) | Medicine for treating woman sterility | |
| CN1211426A (en) | Medicine for treating diabetes | |
| CN1121866C (en) | Chinese medicine for treating man's sexual disfunction and its preparing process | |
| CN1137720C (en) | Chinese medicine for treating diabetes and its complication | |
| CN105994867A (en) | Chocolate with effect of improving immunity and preparation method thereof | |
| CN101045122A (en) | Traditional Chinese medicine composition for tonifying-spleen and nourishing the stomach, and its preparing method | |
| CN101249255A (en) | Proprietary Chinese medicine for curing children's cough and method of preparing the same | |
| CN1611232A (en) | Medicinal composition with main effect of antifatigue, radioresistance and melancholia-resistance and its preparing method | |
| CN1267086C (en) | Medicine for treating diabetes and adjusting blood sugar concentration and its preparation | |
| CN1127344C (en) | Oral pill for curing diabetes and its complication | |
| CN1283285C (en) | Acne treating ointment | |
| CN1294980C (en) | Medicine for treating liver disease | |
| CN1108159C (en) | Traditional Chinese medicine for curing diabetes and kidney deficiency | |
| CN101549057A (en) | Chinese medicine composition for curing hyperlipemia, cerebral arteriosclerosis and ischemic apoplexy and method of preparing the same | |
| CN101181463B (en) | Chinese medicine composition for treating diabetes and method for preparing the same | |
| CN1242800C (en) | Chinese medicine prepn for treating deficiency of spleen and stomach Yin type atrophic gastritis | |
| CN1272054C (en) | Medicine for treating diabetes and its preparing process | |
| CN116920061B (en) | Traditional Chinese medicine composition for treating hyperglycemia and preparation method thereof | |
| CN1814125A (en) | Rehmannia-root preparation | |
| CN1843460A (en) | Medicine for reducing blood sugar, blood pressure and improving microcirculation and immunity, and its preparation method | |
| CN114259540B (en) | Traditional Chinese medicine composition for treating diabetes with syndrome of deficiency of both qi and yin and preparation method and application thereof | |
| CN116159098B (en) | Composition for preventing and treating degenerative osteoarthritis lesions |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C01 | Deemed withdrawal of patent application (patent law 1993) | ||
| WD01 | Invention patent application deemed withdrawn after publication |