CN116077579B - Traditional Chinese medicine preparation for improving ovarian function and helping pregnancy and preparation method thereof - Google Patents
Traditional Chinese medicine preparation for improving ovarian function and helping pregnancy and preparation method thereof Download PDFInfo
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- CN116077579B CN116077579B CN202211040412.9A CN202211040412A CN116077579B CN 116077579 B CN116077579 B CN 116077579B CN 202211040412 A CN202211040412 A CN 202211040412A CN 116077579 B CN116077579 B CN 116077579B
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- ovarian function
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Classifications
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- A61K36/18—Magnoliophyta (angiosperms)
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- A61K33/00—Medicinal preparations containing inorganic active ingredients
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Abstract
The application provides a traditional Chinese medicine preparation for improving ovarian function and assisting pregnancy and a preparation method thereof, and relates to the field of traditional Chinese medicines. A Chinese medicinal preparation for improving ovarian function and helping pregnancy is prepared from the following raw materials: 15-30 parts of stigma croci, 10-20 parts of teasel root, 10-20 parts of glossy privet fruit, 10-20 parts of radix pseudostellariae, 10-20 parts of radix codonopsis, 10-20 parts of hawthorn, 8-15 parts of caulis spatholobi, 8-15 parts of radix bupleuri, 8-15 parts of herba hedyotis diffusae, 8-15 parts of amethyst, 5-12 parts of phellinus linteus, 5-12 parts of radix asparagi, 5-12 parts of capsule and 5-12 parts of liquorice. The Chinese medicinal preparation can effectively improve female ovary function, nourish follicle, and promote female pregnancy probability; the preparation method can exert drug effect maximally.
Description
Technical Field
The application relates to the field of traditional Chinese medicines, in particular to a traditional Chinese medicine preparation for improving ovarian function and assisting pregnancy and a preparation method thereof.
Background
The ovaries are positioned in the uterus, the ovarian function is greatly related to the quality of the uterus environment, and the ovarian function is a disease of female with reduced fertility caused by the decline of the ovarian function, and the primary ovarian function can be related to the functions of kidneys, livers, spleens and hearts, genetic factors, immune factors and the like. Secondary factors include surgery injury to the cortex of the ovary, influence of environmental physicochemical factors, consumption of ovarian reserve caused by age factors, and the like. The western medicine mainly adopts a water passing operation and an ovulation promoting medicine for treating the hypofunction of the ovary, however, the water passing operation can not smoothly dredge a patient with serious oviduct blockage, and the oviduct is damaged by the repeated water passing operation, so that the oviduct function is reduced, and the illness state is aggravated. Meanwhile, the use of hormone ovulation-promoting medicaments seriously affects the balance of female endocrine, aggravates the endocrine dyscrasia originally existing, cannot fundamentally help females to achieve the purpose of pregnancy, and also can damage the body. The traditional Chinese medicine is favored because the traditional Chinese medicine is nontoxic and has no side effect, and can radically improve the ovarian function. At present, the prescription for assisting pregnancy in traditional Chinese medicine mostly uses medicinal materials for tonifying kidney, promoting blood circulation and regulating menstruation, and lacks the coordination of viscera and six fu organs, so that the efficacy of tonifying kidney and tonifying qi cannot be achieved up and down, the efficacy of promoting blood circulation and regulating menstruation cannot be achieved all over the whole body, and the reasons are that liver qi is not smooth, channels and collaterals are not smooth, lung heat is not removed, internal regulation is not discharged, toxin is still in the body, spleen and stomach are weak, strong efficacy is difficult to absorb, and the effect often cannot be expected.
Disclosure of Invention
The application aims to provide a traditional Chinese medicine preparation for improving ovarian function and assisting pregnancy, which can effectively improve female ovarian function, nourish follicles and promote female pregnancy probability.
The application also aims to provide a preparation method of the traditional Chinese medicine preparation for improving ovarian function and helping pregnancy, which can exert the drug effect to the maximum extent.
The application solves the technical problems by adopting the following technical scheme.
In one aspect, the embodiment of the application provides a traditional Chinese medicine preparation for improving ovarian function and helping pregnancy, which is prepared from the following raw materials: 15-30 parts of stigma croci, 10-20 parts of teasel root, 10-20 parts of glossy privet fruit, 10-20 parts of radix pseudostellariae, 10-20 parts of radix codonopsis, 10-20 parts of hawthorn, 8-15 parts of caulis spatholobi, 8-15 parts of radix bupleuri, 8-15 parts of herba hedyotis diffusae, 8-15 parts of amethyst, 5-12 parts of phellinus linteus, 5-12 parts of radix asparagi, 5-12 parts of capsule and 5-12 parts of liquorice.
On the other hand, the embodiment of the application provides a preparation method of a traditional Chinese medicine preparation for improving ovarian function and assisting pregnancy, which comprises the following steps: preparing radix Dipsaci salt into salted radix Dipsaci; making fructus Ligustri Lucidi into wine fructus Ligustri Lucidi; parching fructus crataegi with fire to obtain fructus crataegi; mixing the prepared salted dipsacus root, wine glossy privet fruit and burnt hawthorn with the rest raw material medicines, crushing, drying and sieving to obtain coarse powder; and (3) carrying out ethanol reflux extraction on the coarse powder to obtain an extracting solution, concentrating and drying the extracting solution to obtain micro powder, and preparing the micro powder into the traditional Chinese medicine preparation.
Compared with the prior art, the embodiment of the application has at least the following advantages or beneficial effects:
the traditional Chinese medicine considers that the kidney stores essence, and the kidney is the part of the kidney which is responsible for reproduction and pulse generation, and the functions of the ovary and the uterus have close relation with the kidney. If kidney qi is insufficient and kidney essence is weak, the ovaries cannot have normal sensitivity to ovulation-promoting medicines, so that the ovaries have low response to the ovulation-promoting medicines. The traditional Chinese medicine preparation for improving ovarian function and helping pregnancy provided by the application takes stigma croci Sativi as a monarch drug, has the effects of warming kidney and nourishing liver, promoting blood circulation and regulating menstruation, and improves female ovarian function; the teasel root, the glossy privet fruit, the semen cuscutae, the radix pseudostellariae, the dangshen and the hawthorn are taken as ministerial drugs, and auxiliary monarch drugs have better effects of tonifying liver and kidney and strengthening spleen and replenishing qi, spleen deficiency tends to be weak, and weak body can lead to deficiency of qi and blood of females, so that the ovarian function is reduced or lowered; the radix pseudostellariae, the radix codonopsis and the hawthorn are matched with each other, so that the effects of tonifying qi and yang, strengthening spleen and stimulating appetite are achieved, the spleen and stomach functions of women are further improved, and the physique is enhanced; the glossy privet fruit also has a certain function of resisting bacteria and also provides protection for the maintenance of female ovaries; the Chinese medicinal composition takes the suberect spatholobus stem, the Chinese thorowax root, the common hedyotis herb, the amethyst, the aweto and the Phellinus linteus as adjuvant drugs, not only can tonify the lung and the kidney, promote blood circulation and regulate menstruation, but also has the effects of warming the uterus and expelling toxin, and is matched with monarch drugs and ministerial drugs, so that the medicinal effect can be achieved to the whole body, and the Phellinus linteus can expel toxin of the liver and the kidney and the toxin can be expelled from the body; the amethyst can relieve the hypofunction of the ovary of a female caused by cold uterus; the radix asparagi, the capsule and the liquorice are matched to be used as guiding drugs, which can clear lung heat, dispel wind and remove meridian obstruction, tonify qi, and benefit internal organs; the licorice also has the efficacy of harmonizing the properties of the medicines, and can harmonize the bitter and astringent tastes of the medicines, thereby being convenient for entrance.
The medicines are combined to directly reach focus, so that the female ovarian function can be fundamentally improved, and the purpose of pregnancy assistance is achieved.
The application provides a preparation method of a traditional Chinese medicine preparation for improving ovarian function and helping pregnancy, which can strengthen the drug effect of medicinal materials after radix dipsaci salt preparation, glossy privet fruit wine preparation and hawthorn stir-frying into scorched hawthorn fruit, and can effectively dissolve out active ingredients in the medicinal materials by adopting ethanol reflux extraction, because the main ingredients of some medicinal materials are insoluble in water, such as glossy privet fruit, the preparation method can exert the drug effect to the maximum extent.
Detailed Description
In order to make the objects, technical solutions and advantages of the embodiments of the present application more clear, the technical solutions of the embodiments of the present application will be clearly and completely described below. The specific conditions are not noted in the examples and are carried out according to conventional conditions or conditions recommended by the manufacturer. The reagents or apparatus used were conventional products commercially available without the manufacturer's attention.
It should be noted that, without conflict, the embodiments of the present application and features of the embodiments may be combined with each other. The present application will be described in detail with reference to specific examples.
A Chinese medicinal preparation for improving ovarian function and helping pregnancy is prepared from the following raw materials: 15-30 parts of stigma croci, 10-20 parts of teasel root, 10-20 parts of glossy privet fruit, 10-20 parts of radix pseudostellariae, 10-20 parts of radix codonopsis, 10-20 parts of hawthorn, 8-15 parts of caulis spatholobi, 8-15 parts of radix bupleuri, 8-15 parts of herba hedyotis diffusae, 8-15 parts of amethyst, 5-12 parts of phellinus linteus, 5-12 parts of radix asparagi, 5-12 parts of capsule and 5-12 parts of liquorice.
Xi Hua enters heart and liver meridians. Sweet in flavor and neutral in nature. Has effects in promoting blood circulation, dispelling blood stasis, cooling blood, removing toxic substances, resolving stagnation, and tranquilizing. Can be used for treating amenorrhea, puerperal stagnation, toxic heat, speckle, depression, oppression, palpitation, and mania.
Duan Ji enters liver and kidney meridians. Bitter and pungent in flavor and slightly warm in nature. Has effects in nourishing liver and kidney, strengthening tendons and bones, relieving fracture, and stopping metrorrhagia. Can be used for treating soreness of waist and knees, rheumatalgia, metrorrhagia, metrostaxis, and traumatic injury.
Ligustrum lucidum ait is cool in nature, bitter in taste, sweet in flavor, enters kidney meridian and liver meridian. Has effects in nourishing liver and kidney, and improving eyesight. Can be used for treating dim eyesight, hypopsia, premature gray hair, insomnia, dreaminess, soreness of waist and knees, spermatorrhea, eye pain, hectic fever, vexation, yin deficiency, and diabetes due to yin deficiency of liver and kidney. The glossy privet fruit can also well improve the immunity of the body after long-term adherence, so that the body is stronger and stronger. Some substances contained in glossy privet fruit can well improve the T lymphocyte function in the body, so that a great amount of lymphocytes are propagated, and the glossy privet fruit has a certain resistance to local pathogens.
Radix Pseudostellariae enters spleen and lung meridians. Sweet and slightly bitter in flavor, neutral in nature. Has effects in invigorating qi, invigorating spleen, promoting salivation, and moistening lung. Can be used for treating spleen deficiency, tiredness, inappetence, asthenia after illness, deficiency of qi and yin, spontaneous perspiration, thirst, and dry cough due to lung dryness.
Dang Shen enters spleen and lung meridians. Sweet in flavor and neutral in nature. Has effects in invigorating spleen, replenishing qi, invigorating spleen, and tonifying lung. Can be used for treating spleen and lung weakness, short breath, palpitation, anorexia, loose stool, asthma, cough, internal heat, and diabetes.
Hawthorn enters spleen, stomach and liver meridians. Sour, sweet and slightly warm in nature. Has effects in resolving food stagnation, invigorating stomach, promoting qi circulation, and dispelling blood stasis. Can be used for treating food stagnation, gastric distention, diarrhea, abdominal pain, blood stasis amenorrhea, puerperal stagnation, heart and abdomen pain, hernia pain; hyperlipidemia. The food-digesting and stagnation-removing effects of the charred fructus crataegi are enhanced. It can be used for treating food stagnation, diarrhea, and dysentery.
Spatholobus stem enters liver and kidney meridians. Bitter and sweet in flavor and warm in nature. Has effects in tonifying blood, promoting blood circulation, and expelling collateral obstruction. It can be used for treating menoxenia, blood deficiency, sallow complexion, numbness, paralysis, and rheumatalgia.
Bupleuri radix enters liver and gallbladder meridians. Bitter taste and slightly cold nature. Can relieve exterior and interior syndrome, soothe liver and raise yang. Can be used for treating common cold, fever, distending pain in chest and hypochondrium, menoxenia, prolapse of sub-organ, and rectocele.
He Gen Cao enters liver meridian. Bland in taste and flat in nature. Can eliminate phlegm and relieve cough; promoting blood circulation to regulate menstruation. Cough mainly; hematemesis due to strain; fecal bleeding; dysmenorrhea of women; menoxenia; pain in tendons and bones; sprain and contusion.
Zi-quartz enters heart, lung and kidney meridians. Sweet in flavor and warm in nature. Can relieve heart and calm mind, warm lung and uterus. Can be used for treating insomnia, dreaminess, palpitation, cough, asthma, cold womb, and infertility.
Sang Huanggui liver; kidney meridian. Sweet and bitter; cold nature and pungent nature; is nontoxic. Can promote blood circulation and stop bleeding; dissolving drink; antidiarrheal. Main metrorrhagia; blood stranguria; rectocele purgation; taking down; amenorrhea; mass of the mass; piquanta drink; diarrhea due to spleen deficiency.
Radix asparagi enters the lung; kidney meridian. Sweet and bitter; it is cold in nature. Can nourish yin and moisten dryness; clear lung and reduce fire. Cough due to dryness-heat; cough due to yin deficiency; yin injury due to heat disease; internal heat and diabetes; constipation due to intestinal dryness; sore throat.
The capsule is sweet in taste; slightly bitter; it is cool in nature. Dispelling wind and dredging collaterals; can promote qi circulation. Pain in the stomach; rheumatalgia; uterine prolapse.
Licorice root, radix Glycyrrhizae enters heart, lung, spleen and stomach meridians. Sweet in flavor and neutral in nature. Has effects in invigorating spleen, replenishing qi, clearing away heat and toxic materials, eliminating phlegm, relieving cough, relieving spasm, relieving pain, and regulating the functions of the materials. Can be used for treating weakness of spleen and stomach, listlessness, debilitation, palpitation, short breath, cough with excessive phlegm, abdominal pain, limb spasm, carbuncle, swelling, sore and toxic materials, and relieving drug toxicity and intensity.
In some embodiments of the present application, the above-mentioned Chinese medicinal preparation for improving ovarian function and helping pregnancy is prepared from the following raw materials: 18-25 parts of stigma croci, 12-18 parts of teasel root, 12-18 parts of glossy privet fruit, 12-18 parts of radix pseudostellariae, 12-18 parts of radix codonopsis, 12-18 parts of hawthorn, 8-12 parts of caulis spatholobi, 8-12 parts of radix bupleuri, 8-12 parts of hedyotis diffusa, 8-12 parts of amethyst, 5-10 parts of phellinus linteus, 5-10 parts of radix asparagi, 5-10 parts of capsule and 5-10 parts of liquorice.
In some embodiments of the present application, the above-mentioned Chinese medicinal preparation for improving ovarian function and helping pregnancy is prepared from the following raw materials: 20 parts of saffron, 15 parts of teasel root, 15 parts of glossy privet fruit, 15 parts of radix pseudostellariae, 15 parts of radix codonopsitis, 15 parts of hawthorn, 12 parts of suberect spatholobus stem, 12 parts of radix bupleuri, 12 parts of common hedyotis herb, 12 parts of amethyst, 10 parts of Phellinus linteus, 10 parts of radix asparagi, 10 parts of capsule and 9 parts of liquorice.
A preparation method of a traditional Chinese medicine preparation for improving ovarian function and helping pregnancy comprises the following steps: preparing radix Dipsaci salt into salted radix Dipsaci; making fructus Ligustri Lucidi into wine fructus Ligustri Lucidi; parching fructus crataegi with fire to obtain fructus crataegi; mixing the prepared salted dipsacus root, wine glossy privet fruit and burnt hawthorn with the rest raw material medicines, crushing, drying and sieving to obtain coarse powder; and (3) carrying out ethanol reflux extraction on the coarse powder to obtain an extracting solution, concentrating and drying the extracting solution to obtain micro powder, and preparing the micro powder into the traditional Chinese medicine preparation. Because the main components of some of the medicinal materials are insoluble in water, such as glossy privet fruit, the medicinal effect of the medicinal materials can be stimulated by adopting an ethanol reflux extraction mode.
In some embodiments of the present application, the specific preparation steps of the salt teasel root include: mixing radix Dipsaci with saline, moistening thoroughly, placing into a pan, heating with slow fire, parching to dry, taking out, and cooling. Duan Xuan can guide downward after salt preparation, and strengthen the actions of tonifying liver and kidney.
In some embodiments of the present application, the specific preparation steps of the wine glossy privet fruit are as follows: mixing fructus Ligustri Lucidi with yellow wine, sealing, heating in water or steam until yellow wine is completely absorbed or steamed, taking out, and drying. After the glossy privet fruit wine is prepared, the effect of nourishing liver and kidney can be enhanced, the bitter and cold property of the raw glossy privet fruit is weakened, and the occurrence of diarrhea is relieved.
In some embodiments of the present application, the specific preparation steps of the above-mentioned scorched hawthorn fruit are: cleaning fructus crataegi, slicing, air drying, parching with fire to brown. The burnt hawthorn can not only promote appetite and invigorate spleen, but also regulate menstrual blood, and has the effects of promoting blood circulation and dredging meridians.
In some embodiments of the application, the drying temperature is 25 to 50 ℃ and the moisture content is less than 3wt%. The drying temperature is not too low or too high, and the drying temperature is usually 25-50 ℃ in a proper temperature range; the dried medicinal materials can also prevent mildew, and are generally dried until the water content is less than 3wt% to be suitable.
In some embodiments of the present application, the above-mentioned Chinese medicinal preparation is a decoction, a pill, a capsule, a tablet, a powder or a granule.
The types of the traditional Chinese medicine preparation are only some embodiments of the application, and the traditional Chinese medicine preparation can be cleaned, dried and soaked in grain wine with the alcohol content of 53-60 degrees, so that the application is not limited.
The features and capabilities of the present application are described in further detail below in connection with the examples.
Example 1
A Chinese medicinal preparation for improving ovarian function and helping pregnancy is prepared from the following raw materials: 20g of stigma croci Sativi, 15g of radix Dipsaci, 15g of fructus Ligustri Lucidi, 15g of radix Pseudostellariae, 15g of radix Codonopsis, 15g of fructus crataegi, 12g of caulis Spatholobi, 12g of bupleuri radix, 12g of herba Hedyotidis Diffusae, 12g of Fleckedflesh polypore, 10g of Phellinus linteus, 10g of radix asparagi, 10g of Capsule and 9g of Glycyrrhrizae radix.
The preparation method comprises the following steps:
mixing fructus Ligustri Lucidi with yellow wine, sealing, heating in water or steam until yellow wine is completely absorbed or steamed, taking out, and drying. 20kg of glossy privet fruit is sprinkled with yellow wine per 100 kg.
Cleaning fructus crataegi, cutting into 0.4mm slices, air drying, parching with fire to brown.
Mixing radix Dipsaci with saline, moistening thoroughly, placing into a pan, heating with slow fire, parching to dry, taking out, and cooling. Every 100kg of teasel root uses 2kg of salt.
Mixing the prepared salted dipsacus root, fructus Ligustri Lucidi, and fructus crataegi preparata with the rest raw materials, pulverizing at room temperature, drying at 35deg.C, and sieving to obtain coarse powder; reflux extracting the coarse powder with ethanol, concentrating the extractive solution, drying at 35deg.C until the water content is less than 3wt% to obtain micropowder, making into pill by conventional pill preparation method, and packaging into 8 g/granule.
Example 2
A Chinese medicinal preparation for improving ovarian function and helping pregnancy is prepared from the following raw materials: 18g of saffron, 12g of teasel root, 12g of glossy privet fruit, 12g of radix pseudostellariae, 12g of radix codonopsitis, 12g of hawthorn, 8g of suberect spatholobus stem, 8g of radix bupleuri, 8g of common hedyotis herb, 8g of amethyst, 12g of Phellinus linteus, 12g of radix asparagi, 12g of capsule and 9g of liquorice.
The preparation process was essentially the same as that of example 1, except that the drying temperature was 25℃and the water content was less than 3% by weight.
Example 3
A Chinese medicinal preparation for improving ovarian function and helping pregnancy is prepared from the following raw materials: 22g of stigma croci Sativi, 15g of radix Dipsaci, 13g of fructus Ligustri Lucidi, 13g of radix Pseudostellariae, 13g of radix Codonopsis, 13g of fructus crataegi, 9g of caulis Spatholobi, 9g of bupleuri radix, 9g of herba Hedyotidis Diffusae, 9g of Fleckedflesh polypore, 6g of Phellinus linteus, 6g of radix asparagi, 6g of capsule of herba Equiseti Arvinsis and 6g of Glycyrrhrizae radix.
The preparation process was essentially the same as that of example 1, except that the drying temperature was 50℃and the water content was less than 3% by weight.
Example 4
A Chinese medicinal preparation for improving ovarian function and helping pregnancy is prepared from the following raw materials: 15g of saffron, 15g of teasel root, 10g of glossy privet fruit, 10g of radix pseudostellariae, 10g of radix codonopsitis, 10g of hawthorn, 15g of suberect spatholobus stem, 15g of radix bupleuri, 15g of common hedyotis herb, 15g of amethyst, 5g of Phellinus linteus, 5g of radix asparagi, 5g of capsule and 5g of liquorice.
The preparation process was essentially the same as that of example 1, except that the drying temperature was 40℃and the water content was less than 3% by weight.
Example 5
A Chinese medicinal preparation for improving ovarian function and helping pregnancy is prepared from the following raw materials: 30g of stigma croci Sativi, 20g of radix Dipsaci, 20g of fructus Ligustri Lucidi, 12g of radix Pseudostellariae, 12g of radix Codonopsis, 10g of fructus crataegi, 8g of caulis Spatholobi, 8g of bupleuri radix, 8g of herba Hedyotidis Diffusae, 8g of Fleckedflesh polypore, 5g of Phellinus linteus, 5g of radix asparagi, 5g of capsule of herba Equiseti Arvinsis and 12g of Glycyrrhrizae radix.
The preparation process was essentially the same as that of example 1, except that the drying temperature was 30℃and the water content was less than 3% by weight.
Example 6
A Chinese medicinal preparation for improving ovarian function and helping pregnancy is prepared from the following raw materials: 28g of stigma croci Sativi, 12g of radix Dipsaci, 12g of fructus Ligustri Lucidi, 20g of radix Pseudostellariae, 20g of radix Codonopsis, 20g of fructus crataegi, 12g of caulis Spatholobi, 12g of bupleuri radix, 12g of herba Hedyotidis Diffusae, 12g of Fleckedflesh polypore, 8g of Phellinus linteus, 8g of radix asparagi, 8g of capsule of Chinese medicinal materials and 10g of Glycyrrhrizae radix.
The preparation process was essentially the same as that of example 1, except that the drying temperature was 45℃and the water content was less than 3% by weight.
Example 7
This example is basically the same as example 4 except that in the preparation method, the fine powder is prepared into capsules according to a usual capsule preparation method, and the capsules are packaged to have a drug content of 0.5g each.
Typical case 1: liu Nvshi, 37 years old. Multiple pregnant abortions after wedding, diagnosis by a doctor after pregnancy, inability to become pregnant, and pregnancy after 4 months after taking the traditional Chinese medicine preparation of example 1, smooth birth of the next healthy male infant.
Typical case 2: women, 36 years old. Many years after wedding, the birth is not carried out, the patients seek medical attention, the patients still cannot become pregnant, and the next healthy male infant can be born smoothly after the traditional Chinese medicine preparation of the embodiment 1 is taken for 5 months.
Typical case 3: women, age 37. The traditional Chinese medicine preparation of the example 2 is taken for the first time, then is not pregnant, and the traditional Chinese medicine preparation provided by the application is taken for the second time after 5 months, and then is pregnant for the next healthy boy after the 2 nd month.
Typical case 4: song women, 35 years old. Many years after the wedding have passed without pregnancy, and once many hospitals have been working, the patients are not born, and after the traditional Chinese medicine preparation of example 3 is taken, the patients are pregnant at 2022, 1 month.
Typical case 5: ladies, 31 years old. The male and female women were not bred for 4 years after the wedding, the two couples were checked in the hospital, the female women were irregular, the male sexual functions were normal, the Chinese and western medicines were taken, but the effects were not achieved, and the female women were pregnant for 3 months after taking the Chinese medicinal preparation of example 4, and a healthy female infant was born.
Typical case 6: women with a fiddle period of 38 years. Over ten years after wedding, the women have not been bred, the women are diagnosed as uterine atrophy and cannot grow, and after taking the traditional Chinese medicine preparation of example 5 for 5 months, the women become pregnant and the next healthy baby girls take.
Typical case 7: which women, age 27. Years after wedding, women have no fertility, women have irregular menstruation, and pregnant for 3 months after taking the traditional Chinese medicine preparation of example 6, and a healthy male infant is born.
Typical case 8: women, 25 years old. The women had no birth for more than 3 years after the wedding, and the women had irregular menstruation and dysmenorrhea, and the women were pregnant and had a healthy baby girl after taking the Chinese herbal preparation of example 6 for 3 months.
Typical case 9: women, 28 years old. The pregnant women were not pregnant 5 years after the wedding, and the pregnant women were pregnant after the multiparty treatment, and a healthy female infant was born after 3 months after taking the traditional Chinese medicine preparation of example 3.
In conclusion, the traditional Chinese medicine preparation for improving ovarian function and helping pregnancy provided by the embodiment of the application takes stigma croci Sativi as a monarch drug, has the effects of warming kidney, nourishing liver, promoting blood circulation, regulating menstruation and improving female ovarian function; the teasel root, the glossy privet fruit, the semen cuscutae, the radix pseudostellariae, the dangshen and the hawthorn are taken as ministerial drugs, and auxiliary monarch drugs have better effects of tonifying liver and kidney and strengthening spleen and replenishing qi, spleen deficiency tends to be weak, and weak body can lead to deficiency of qi and blood of females, so that the ovarian function is reduced or lowered; the radix pseudostellariae, the radix codonopsis and the hawthorn are matched with each other, so that the effects of tonifying qi and yang, strengthening spleen and stimulating appetite are achieved, the spleen and stomach functions of women are further improved, and the physique is enhanced; the glossy privet fruit also has a certain function of resisting bacteria and also provides protection for the maintenance of female ovaries; the Chinese medicinal composition takes the suberect spatholobus stem, the Chinese thorowax root, the common hedyotis herb, the amethyst, the aweto and the Phellinus linteus as adjuvant drugs, not only can tonify the lung and the kidney, promote blood circulation and regulate menstruation, but also has the effects of warming the uterus and expelling toxin, and is matched with monarch drugs and ministerial drugs, so that the medicinal effect can be achieved to the whole body, and the Phellinus linteus can expel toxin of the liver and the kidney and the toxin can be expelled from the body; the amethyst can relieve the hypofunction of the ovary of a female caused by cold uterus; the radix asparagi, the capsule and the liquorice are matched to be used as guiding drugs, which can clear lung heat, dispel wind and remove meridian obstruction, tonify qi, and benefit internal organs; the licorice also has the efficacy of harmonizing the properties of the medicines, and can harmonize the bitter and astringent tastes of the medicines, thereby being convenient for entrance.
The medicines are combined to directly reach focus, so that the female ovarian function can be fundamentally improved, and the purpose of pregnancy assistance is achieved.
The application provides a preparation method of a traditional Chinese medicine preparation for improving ovarian function and helping pregnancy, which can strengthen the drug effect of medicinal materials after radix dipsaci salt preparation, glossy privet fruit wine preparation and hawthorn stir-frying into scorched hawthorn fruit, and can effectively dissolve out active ingredients in the medicinal materials by adopting ethanol reflux extraction, because the main ingredients of some medicinal materials are insoluble in water, such as glossy privet fruit, the preparation method can exert the drug effect to the maximum extent.
The embodiments described above are some, but not all embodiments of the application. The detailed description of the embodiments of the application is not intended to limit the scope of the application, as claimed, but is merely representative of selected embodiments of the application. All other embodiments, which can be made by those skilled in the art based on the embodiments of the application without making any inventive effort, are intended to be within the scope of the application.
Claims (9)
1. The Chinese medicinal preparation for improving ovarian function and helping pregnancy is characterized by being prepared from the following raw materials: 15-30 parts of stigma croci, 10-20 parts of teasel root, 10-20 parts of glossy privet fruit, 10-20 parts of radix pseudostellariae, 10-20 parts of radix codonopsis, 10-20 parts of hawthorn, 8-15 parts of caulis spatholobi, 8-15 parts of radix bupleuri, 8-15 parts of herba hedyotis diffusae, 8-15 parts of amethyst, 5-12 parts of phellinus linteus, 5-12 parts of radix asparagi, 5-12 parts of capsule and 5-12 parts of liquorice.
2. The traditional Chinese medicine preparation for improving ovarian function and helping pregnancy according to claim 1, which is characterized by being prepared from the following raw materials: 18-25 parts of stigma croci, 12-18 parts of teasel root, 12-18 parts of glossy privet fruit, 12-18 parts of radix pseudostellariae, 12-18 parts of radix codonopsis, 12-18 parts of hawthorn, 8-12 parts of caulis spatholobi, 8-12 parts of radix bupleuri, 8-12 parts of hedyotis diffusa, 8-12 parts of amethyst, 5-10 parts of phellinus linteus, 5-10 parts of radix asparagi, 5-10 parts of capsule and 5-10 parts of liquorice.
3. The traditional Chinese medicine preparation for improving ovarian function and helping pregnancy according to claim 2, which is characterized by being prepared from the following raw materials: 20 parts of saffron, 15 parts of teasel root, 15 parts of glossy privet fruit, 15 parts of radix pseudostellariae, 15 parts of radix codonopsitis, 15 parts of hawthorn, 12 parts of suberect spatholobus stem, 12 parts of radix bupleuri, 12 parts of common hedyotis herb, 12 parts of amethyst, 10 parts of Phellinus linteus, 10 parts of radix asparagi, 10 parts of capsule and 9 parts of liquorice.
4. A method for preparing a traditional Chinese medicine preparation for improving ovarian function and helping pregnancy according to any one of claims 1-3, which comprises the following steps:
preparing radix Dipsaci salt into salted radix Dipsaci;
making fructus Ligustri Lucidi into wine fructus Ligustri Lucidi;
parching fructus crataegi with fire to obtain fructus crataegi;
mixing the prepared salted dipsacus root, wine glossy privet fruit and burnt hawthorn with the rest raw material medicines, crushing, drying and sieving to obtain coarse powder; and (3) carrying out ethanol reflux extraction on the coarse powder to obtain an extracting solution, concentrating and drying the extracting solution to obtain micro powder, and preparing the micro powder into the traditional Chinese medicine preparation.
5. The preparation method of the traditional Chinese medicine preparation for improving ovarian function and helping pregnancy according to claim 4, which is characterized in that the specific preparation steps of the radix dipsaci comprise: mixing radix Dipsaci with saline, moistening thoroughly, placing into a pan, heating with slow fire, parching to dry, taking out, and cooling.
6. The preparation method of the traditional Chinese medicine preparation for improving ovarian function and helping pregnancy according to claim 4, wherein the specific preparation steps of the wine glossy privet fruit are as follows: mixing fructus Ligustri Lucidi with yellow wine, sealing, heating in water or steam until yellow wine is completely absorbed or steamed, taking out, and drying.
7. The preparation method of the traditional Chinese medicine preparation for improving ovarian function and helping pregnancy according to claim 4, wherein the specific preparation steps of the scorched hawthorn fruit are as follows: cleaning fructus crataegi, slicing, air drying, parching with fire to brown.
8. The method for preparing a Chinese medicinal preparation for improving ovarian function and helping pregnancy according to claim 4, wherein the drying temperature is 25-50 ℃, and the water content is less than 3wt%.
9. The method for preparing a Chinese medicinal preparation for improving ovarian function and helping pregnancy according to claim 4, wherein the Chinese medicinal preparation is decoction, pill, capsule, tablet, powder or granule.
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| CN202211040412.9A CN116077579B (en) | 2022-08-29 | 2022-08-29 | Traditional Chinese medicine preparation for improving ovarian function and helping pregnancy and preparation method thereof |
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Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104042829A (en) * | 2014-07-06 | 2014-09-17 | 杨天梅 | Kidney-tonifying pregnancy-promotion soup |
| CN108030837A (en) * | 2018-02-09 | 2018-05-15 | 袁丽丽 | A kind of Chinese medicine and its application method for being used to treat female infertility |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104042829A (en) * | 2014-07-06 | 2014-09-17 | 杨天梅 | Kidney-tonifying pregnancy-promotion soup |
| CN108030837A (en) * | 2018-02-09 | 2018-05-15 | 袁丽丽 | A kind of Chinese medicine and its application method for being used to treat female infertility |
Non-Patent Citations (1)
| Title |
|---|
| 张良英教授助孕Ⅰ号方治疗排卵障碍性不孕症疗效观察;王志梅;周晓娜;岳胜难;陈林兴;;云南中医学院学报;-(05);91-93 * |
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