CN106377644A - Traditional Chinese medicine composition for treating deficiency of qi and blood and preparation method of traditional Chinese medicine composition - Google Patents

Traditional Chinese medicine composition for treating deficiency of qi and blood and preparation method of traditional Chinese medicine composition Download PDF

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CN106377644A
CN106377644A CN201610992066.2A CN201610992066A CN106377644A CN 106377644 A CN106377644 A CN 106377644A CN 201610992066 A CN201610992066 A CN 201610992066A CN 106377644 A CN106377644 A CN 106377644A
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parts
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blood
donkey
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黄烜
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Dongguan Biological Technology Co Ltd
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Dongguan Biological Technology Co Ltd
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    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
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    • A61K36/07Basidiomycota, e.g. Cryptococcus
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    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/481Astragalus (milkvetch)
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    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/484Glycyrrhiza (licorice)
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    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/53Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/538Schizonepeta
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    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/71Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
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    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/72Rhamnaceae (Buckthorn family), e.g. buckthorn, chewstick or umbrella-tree
    • A61K36/725Ziziphus, e.g. jujube
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    • A61K36/73Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/73Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
    • A61K36/739Sanguisorba (burnet)
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    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/80Scrophulariaceae (Figwort family)
    • A61K36/804Rehmannia
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    • A61K2236/30Extraction of the material
    • A61K2236/33Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/331Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
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    • A61K2236/50Methods involving additional extraction steps
    • A61K2236/51Concentration or drying of the extract, e.g. Lyophilisation, freeze-drying or spray-drying

Abstract

The invention discloses a traditional Chinese medicine composition for treating deficiency of qi and blood and a preparation method of the traditional Chinese medicine composition. The traditional Chinese medicine composition is prepared from the following raw materials in parts by weight: 120-180 parts of radix angelicae sinensis, 170-230 parts of radix paeoniae alba, 170-230 parts of radix rehmanniae preparata, 170-230 parts of carbonized radix sanguisorbae, 170-230 parts of fructus corni, 120-180 parts of colla corii asini, 200-400 parts of radix codonopsis, 200-400 parts of herba taxilli, 400-600 parts of radix astragali, 120-180 parts of rhizoma atractylodis macrocephalae, 120-180 parts of herba schizonepetae, 120-180 parts of cacumen platycladi, 120-180 parts of fructus rubi, 60-120 parts of prepared rhizoma cyperi, 40-80 parts of honey-fried liquorice root, 120-180 parts of fried cortex eucommiae, 120-180 parts of poria cocos, 120-180 parts of radix dipsaci, 60-80 parts of sucrose and 0.001-0.002 part of potassium sorbate. The traditional Chinese medicine composition has the efficacy of warming channel, expelling cold, benefiting qi and nourishing blood, is high in effective rate, definite in curative effect and convenient to take and is safe and non-toxic.

Description

A kind of Chinese medicine composition treating deficiency of qi and blood and preparation method
Technical field
The present invention relates to the field of Chinese medicines is and in particular to a kind of Chinese medicine composition treating deficiency of qi and blood and preparation method.
Background technology
Deficiency of qi and blood, the traditional Chinese medical science thinks that qi and blood is that people is basic, the impact to body of the deficiency of vital energy, the deficiency of blood, simply in short, It is that the deficiency of vital energy is powerless, the deficiency of blood is sent out dry, long-term insufficiency of vital energy and blood can cause hypoimmunity, and what disease all may obtain, and is most commonly that Flu, tracheitis, pharyngitis, rhinitis, Bronchopneumonia, pneumonia, the indigestion of digestive system, gastritis, enteritis, gastroenteritis, just Multiple diseases such as dilute, gas and blood are the base substances of group adult body, are related to the operation of internal organs function and the health of body, gas simultaneously Blood plays the role of to link up each internal organs, so the qi and blood of internal organs is not normal, not only can cause the pathology of this internal organs, can also simultaneously Cause the qi and blood of other internal organs not normal, or even the qi and blood of whole body is not normal;Some people of symptom palpitaition of deficiency of qi and blood are because throughout the year Work is worked hard, and body and mind is all tired, often has heartbeat to obtain sensation quickly, very heavy, just as having individual bunny in disorderly spring in one's arms;Simultaneously The symptom of palpitaition also can after physical exertion, have a meal after, or even increase when nervous, have a strong impact on the normal of people Work and life, in the traditional Chinese medical science, this is weak;This weakness is due to the dirty weakness of liver spleen two, then derives as deficiency of qi and blood institute Cause, the ice-cold trick of trick is ice-cold to be a common phenomenon, occurs in the middle of women, these people always bend over one's desk working at ordinary times, very more Rare time motion, or simply just do not move, the time one is long, the miopragia of the heart, and blood flow is slack-off, and energy cannot favour And four limbs, so the ice-cold problem of trick, from the viewpoint of the traditional Chinese medical science, trick is easily ice-cold, numb, belongs to qi and blood more Defect, because the blood operation caused by qi-blood deficiency is not smooth, blood flow volume is not enough, therefore, easily hand in the case of asthenia of qi and blood The ice-cold symptom of pin, be generally present in anaemia, leukopenia, thrombopenia, after massive haemorrhage, the excessive person of woman in menstrual period Deng it is mainly shown as;The performance of the existing deficiency of vital energy, has the performance of the deficiency of blood again, nourish preferably using benefiting qi for promoting production of blood, training fill blood, gas Blood is simultaneously mended, and this type symptom is common to have urine dripping not smooth, or urethral orifice has foul logistics to go out, or under band is abnormal, lower abdominal distention pain, Tongue is dark, and tongue is white, small and wiry pulse, and this is due to pathogen usually intruding into collateral in protracted disease, or due to damp and hot heresy obstruction of meridian, caused by qi and blood stagnation, treatment is preferably The promoting flow of qi and blood circulation, changes turbid pain relieving, and the deficiency of vital energy, often because of feeding desorder, is got old and weak, and caused by prolonged illness, clinical manifestation goes out function decline Syndrome, the deficiency of blood is so that internal organs is lost in moistening foster showed syndrome because blood is not enough, and the application on human skin of asthenia of qi and blood is no longer Glossy, organ function is weak, wants recuperating qi-blood two empty, then just tonifying Qi should combine with enriching blood;In prior art The Chinese medicine preparation for the treatment of deficiency of qi and blood is taken for patient, though having the effect of mitigation symptoms, curative effect is inconspicuous.
Content of the invention
Not enough for prior art, the technical problem to be solved in the invention is that and overcomes existing treatment deficiency of qi and blood Western medicine treatment effect is undesirable and the defect of large side effects, provides one kind to treat deficiency of qi and blood with strong points, evident in efficacy and secondary Act on little Chinese medicine composition, this drug therapy deficiency of qi and blood has functions that warming channel and expelling cold, benefiting qi and nourishing blood, efficient height, treats Effect is definite, easy to use, safe nontoxic.
In order to realize foregoing invention purpose, the present invention adopts the following technical scheme that:
A kind of Chinese medicine composition treating deficiency of qi and blood, is made up of the raw material of following weight portion:Radix Angelicae Sinensis 120-180 part, the root of herbaceous peony 170-230 part, prepared rhizome of rehmannia 170-230 part, charred RADIX SANGUISORBAE 170-230 part, fructus corni 170-230 part, donkey-hide gelatin 120-180 part, Radix Codonopsis 200-400 part, parasitic loranthus 200-400 part, Radix Astragali 400-600 part, bighead atractylodes rhizome 120-180 part, schizonepeta 120-180 part, cacumen biotae 120-180 part, raspberry 120-180 part, rhizoma cyperi 60-120 part processed, honey-fried licorice root 40-80 part, stir-baked CORTEX EUCOMMIAE 120-180 part, Poria cocos 120-180 part, teasel root 120-180 part, sucrose 60-80 part, potassium sorbate 0.001-0.002 part;
Its preparation process is:
(1)Raw material Radix Angelicae Sinensis, the root of herbaceous peony, fructus corni, raspberry is taken to be pulverized, grinding particle size is 30-50 mesh, obtains raw material powder, standby;
(2)Take raw material donkey-hide gelatin, donkey-hide gelatin is milled to powder, granularity is 80-150 mesh, be placed in container and add opening of its weight 3-5 times amount After water, container is put into water proof heating in steamer and steams 25-65 minute, until donkey-hide gelatin dissolves, obtain donkey-hide gelatin dissolving liquid, standby;
(3)Take raw material Radix Codonopsis, parasitic loranthus, the Radix Astragali, the bighead atractylodes rhizome, schizonepeta, cacumen biotae, prepared rhizome of rehmannia, charred RADIX SANGUISORBAE, rhizoma cyperi processed, honey-fried licorice root, stir-fry The bark of eucommia, Poria cocos, teasel root are pulverized, and grinding particle size is 80-100 mesh, obtains raw material powder, standby;
(4)By step(1)Gained raw material powder and step(3)Gained original powder mixing and water adding decocts three after soaking 0.5-0.9 hour Secondary, add the 6-10 times amount decocting of raw material gross weight to boil 0.5-0.9 hour for the first time, pour out liquid, add for second raw material total The 6-10 times amount decocting of weight boils 0.5-0.9 hour, pours out liquid, and third time adds the 6-10 times amount decocting of raw material gross weight to boil 0.5-0.9 hour, merges three liquids, stands 8-12 hour, filters, and filtrate reduced in volume becomes 40-60 DEG C of survey relative density 1.02-1.15 medicinal extract, standby;
(5)By step(4)Middle gained medicinal extract and step(2)Gained donkey-hide gelatin dissolving liquid mixes, and adds the 2.5-5.5 of mixed liquor weight The purified water of times amount, stirring 15-30 minute, so as to be sufficiently mixed, carries out reduced pressure concentration to liquid, and thickening temperature is 60-65 DEG C, Steam pressure is 0.025-0.035Mpa, and vacuum is 0.065-0.085Mpa, controls relative density of medicine liquid in 1.25-1.35, Form concentration of liquid medicine liquid, standby;
(6)By step(5)Middle gained concentration of liquid medicine liquid adds the purified water of the 2.5-5.5 times amount of weight, adds sucrose and mountain Potassium sorbate, is heated to seething with excitement, stirs 10-20 minute, and micro-boiling rises insulation 10-20 minute, is filtered using centrifuge, is cooled to Room temperature, filling with clear glass bottle, irradiate the sterilizing of 20-40 minute, packaging under uviol lamp, obtain final product the Chinese medicine for the treatment of deficiency of qi and blood Composition.
It is further preferred that a kind of Chinese medicine composition treating deficiency of qi and blood, it is made up of the raw material of following weight portion:Radix Angelicae Sinensis 150 parts, 200 parts of the root of herbaceous peony, 200 parts of prepared rhizome of rehmannia, 200 parts of charred RADIX SANGUISORBAE, 200 parts of fructus corni, 150 parts of donkey-hide gelatin, 300 parts of Radix Codonopsis, parasitic loranthus 300 parts, 500 parts of the Radix Astragali, 150 parts of the bighead atractylodes rhizome, 150 parts of schizonepeta, 150 parts of cacumen biotae, 150 parts of raspberry, 90 parts of rhizoma cyperi processed, honey-fried licorice root 60 parts, 150 parts of stir-baked CORTEX EUCOMMIAE, 150 parts of Poria cocos, 150 parts of teasel root, 70 parts of sucrose, 0.0015 part of potassium sorbate;
Its preparation process is:
(1)Raw material Radix Angelicae Sinensis, the root of herbaceous peony, fructus corni, raspberry is taken to be pulverized, grinding particle size is 50 mesh, obtains raw material powder, standby;
(2)Take raw material donkey-hide gelatin, donkey-hide gelatin be milled to powder, granularity is 80 mesh, be placed in container plus after the boiling water of its weight 5 times amount, Container is put into water proof heating in steamer steam 45 minutes, until donkey-hide gelatin dissolves, obtain donkey-hide gelatin dissolving liquid, standby;
(3)Take raw material Radix Codonopsis, parasitic loranthus, the Radix Astragali, the bighead atractylodes rhizome, schizonepeta, cacumen biotae, prepared rhizome of rehmannia, charred RADIX SANGUISORBAE, rhizoma cyperi processed, honey-fried licorice root, stir-fry The bark of eucommia, Poria cocos, teasel root are pulverized, and grinding particle size is 80 mesh, obtains raw material powder, standby;
(4)By step(1)Gained raw material powder and step(3)Gained original powder mixing and water adding decocts three times after soaking 0.5 hour, the Once add 10 times amount decoctings of raw material gross weight to boil 0.7 hour, pour out liquid, 10 times amount that second adds raw material gross weight Decocting boils 0.7 hour, pours out liquid, and third time adds 10 times amount decoctings of raw material gross weight to boil 0.7 hour, merges three medicines Liquid, stands 8 hours, filters, and filtrate reduced in volume becomes the medicinal extract of 60 DEG C of survey relative densities 1.02, standby;
(5)By step(4)Middle gained medicinal extract and step(2)Gained donkey-hide gelatin dissolving liquid mixes, and adds 4 times amount of mixed liquor weight Purified water, stirring carries out reduced pressure concentration so as to be sufficiently mixed to liquid in 15 minutes, and thickening temperature is 65 DEG C, and steam pressure is 0.025Mpa, vacuum is 0.065Mpa, controls relative density of medicine liquid 1.25, forms concentration of liquid medicine liquid, standby;
(6)By step(5)Middle gained concentration of liquid medicine liquid adds the purified water of 4 times amount of weight, adds sucrose and potassium sorbate, It is heated to seething with excitement, stirs 10 minutes, micro-boiling rises insulation 10 minutes, is filtered using centrifuge, is cooled to room temperature, uses clean glass Glass bottle is filling, irradiates sterilizing in 35 minutes, packaging, obtain final product the Chinese medicine composition for the treatment of deficiency of qi and blood under uviol lamp.
The pharmacological action of each bulk drug:
Radix Angelicae Sinensis:Meridian distribution of property and flavor:Sweet, acrid, warm, Return liver, the heart, the spleen channel;Indication:Replenishing and activating blood, menstruction regulating and pain relieving, relax bowel; For blood deficiency chlorosis, dizziness palpitaition, irregular menstruation, closed dysmenorrhea, asthenia cold abdominalgia, dry constipation of intestines, arthralgia due to wind-dampness, injury from falling down, Ulcer sores.
The root of herbaceous peony:Meridian distribution of property and flavor:Bitter, sour, it is slightly cold, Return liver, the spleen channel;Indication:Smooth liver and relieve pain, nourishing blood for regulating menstruation, hold back the moon and stop Sweat;For dizziness of having a headache, hypochondriac pain, stomachache, four limbs contraction pain, blood deficiency chlorosis, irregular menstruation, spontaneous perspiration, night sweat.
Prepared rhizome of rehmannia:Meridian distribution of property and flavor:Sweet, tepor, return liver and kidney channel;Indication:Nourishing yin and supplementing blood, beneficial essence fills out marrow;For liver kidney The deficiency of Yin, soreness and weakness of waist and knees, osteopyrexia and fever, night sweat is passed out semen, Heat Diabetes, blood deficiency chlorosis, palpitation and severe palpitation, irregular menstruation, metrostaxis, Dizziness, tinnitus, poliosis.
Charred RADIX SANGUISORBAE:Nature and flavor:Bitter, sour, puckery, it is slightly cold, Return liver, large intestine channel;Effect:Cooling blood and hemostasis, removing toxic substances sore;Cure mainly:With In having blood in stool, hemorrhoid blood, bloody flux, uterine bleeding, scald, carbuncle sore tumefacting virus.
Fructus corni:Meridian distribution of property and flavor:Sour, puckery, tepor, return liver and kidney channel;Indication:Tonify the liver and kidney, convergence is astringent or styptic treatment for spontaneous sweating, controlling nocturnal emission with astringent drugs contracts Urine, only carries and only collapses, hidroschesis, in addition with promoting the production of body fluid to quench thirst;For soreness of waist and knee joint, dizziness and tinnitus, forgetful, emission and spermatorrhea, the enuresis is urinated Frequently, uterine bleeding under band, irregular menstruation, profuse sweating is collapsed, Heat Diabetes.
Donkey-hide gelatin:Gas is micro-, taste micro-sweet;Enrich blood enriching yin, moisturize, hemostasis;For blood deficiency chlorosis, dizziness palpitaition, dysphoria and insomnia, lung Cough caused by dryness is coughed.
Radix Codonopsis:Meridian distribution of property and flavor:Sweet, put down, returns spleen, lung channel;Indication:Tonifying middle-Jiao and Qi, strengthening spleen and tonifying lung;Empty for spleen and lung Weak, shortness of breath palpitations, anorexia and loose stool, virtual asthma cough, Heat Diabetes.
Parasitic loranthus:Meridian distribution of property and flavor:Bitter, sweet, flat, Return liver, kidney channel;Effect:Wines used as antirheumatic, filling liver kidney, strengthening the bones and muscles, antiabortive;Main Control:For arthralgia due to wind-dampness, soreness of waist and knee joint, blood under threatened abortion, fetal irritability.
The Radix Astragali:Meridian distribution of property and flavor:Sweet, temperature, return lung, the spleen channel;Indication:Invigorating qi for strengthening superficies, diuretic and maintain drug, apocenosis, sore is given birth to Flesh;For treatment deficiency of vital energy weak, anorexia and loose stool, the sinking of qi of middle-jiao, rush down prolapse of the anus for a long time, uterine bleeding of having blood in stool, exterior deficiency spontaneous perspiration, deficiency of vital energy oedema, ulcer is difficult Burst, bursts for a long time and does not holds back, flaccidity of limbs due to deficiency of blood is yellow, Heat Diabetes;Chronic rephrilis protinuria, diabetes.
The bighead atractylodes rhizome:Meridian distribution of property and flavor:Bitter, sweet, temperature, returns spleen, stomach;Indication:Strengthening the spleen and replenishing qi, eliminate dampness and have diuretic effect, hidroschesis, peace Tire;For spleen eating less, abdominal distention diarrhea, phlegm retention anti-dazzle nervous, oedema, spontaneous perspiration, fetal irritability.
Schizonepeta:Meridian distribution of property and flavor:Pungent, tepor, return lung, Liver Channel;Indication:Induce sweat scattered wind, promoting eruption;For catching a cold, headache, Measles, rubella, sore from the beginning of;Fry charcoal treating hematochezia, uterine bleeding, postpartum anemic fainting.
Cacumen biotae:Meridian distribution of property and flavor:Bitter, puckery, tremble with fear, return lung, liver, the spleen channel;Indication:Cooling blood and hemostasis, growing and blacking hair;For Hematemesis and epistaxis, spitting of blood, have blood in stool, metrostaxis, blood-head alopecia, poliosis.
Raspberry:Meridian distribution of property and flavor:Sweet, sour, temperature, return kidney, bladder warp;Indication:Kidney-nourishing, controlling nocturnal emission with astringent drugs, contracting urine;For kidney deficiency The enuresis, frequent urination, impotence and premature ejaculation, emission and spermatorrhea.
Rhizoma cyperi processed:Meridian distribution of property and flavor:Pungent, slight bitter, micro-sweet, put down, Return liver, spleen, tri-jiao channel;Indication:Promoting qi circulation and removing obstruction in the collateral, menstruation regulating Pain relieving;For stagnation of QI due to depression of the liver, chest, the side of body, abdominal distention, indigestion, chest gastral cavity ruffian, cold hernia stomachache, swollen breasts, menstruation is not Adjust, closed dysmenorrhea.
Honey-fried licorice root:Mild-natured, sweet, the thoughts of returning home, spleen, lung, stomach;Effect:Help;Indication:Invigorate the spleen and benefit qi, heat-clearing solution Poison, expelling phlegm and arresting coughing, relieving spasm to stop pain, coordinating the drug actions of a prescription;For weakness of the spleen and the stomach, lassitude hypodynamia, palpitation, coughing with a lot of sputum, gastral cavity abdomen, four Limb contraction urgency pain, carbuncle sore tumefacting virus, alleviate drug toxicity, strong.
Stir-baked CORTEX EUCOMMIAE:Meridian distribution of property and flavor:Sweet, temperature, return liver and kidney channel;Indication:Filling liver kidney, strengthening the bones and muscles, antiabortive;For kidney deficiency Pain in the back, muscles and bones is powerless, blood leaking in gestation, fetal irritability;Hypertension.
Poria cocos:Meridian distribution of property and flavor:Sweet, light, put down, the thoughts of returning home, lung, spleen, kidney channel;Indication:Clearing damp and promoting diuresis, invigorating the spleen calming heart;With In oedema oliguria, phlegm retention anti-dazzle nervous, spleen eating less, have loose bowels in loose stool, confused and worried, insomnia of palpitating with fear.
Teasel root:Meridian distribution of property and flavor:Bitter, pungent, slightly warm in nature, return liver and kidney channel;Effect filling liver kidney, strengthening the bones and muscles, adjust blood vessels, Continuous injured, only uterine bleeding;For aching pain in waist and back, podomere Impotence numbness, fall and flutter wound, damage muscle folding bone, the movement of the foetus red, metrorrhagia of leakage, seminal emission, band Under, ulcer sore swells;Prepared RADIX DIPSACI with yellow rice wine is used for arthralgia due to wind-dampness, injury from falling down;Prepared RADIX DIPSACI with salt solution is used for soreness and weakness of waist and knees.
Beneficial effects of the present invention are:This drug therapy deficiency of qi and blood has functions that warming channel and expelling cold, benefiting qi and nourishing blood, effectively Rate is high, determined curative effect, easy to use, safe nontoxic.
Specific embodiment
With reference to embodiment, the present invention is expanded on further.
Embodiment 1
A kind of Chinese medicine composition treating deficiency of qi and blood, is made up of the raw material of following weight portion:180 parts of Radix Angelicae Sinensis, 230 parts of the root of herbaceous peony, 230 parts of prepared rhizome of rehmannia, 230 parts of charred RADIX SANGUISORBAE, 230 parts of fructus corni, 180 parts of donkey-hide gelatin, 400 parts of Radix Codonopsis, 400 parts of parasitic loranthus, 600 parts of the Radix Astragali, 180 parts of the bighead atractylodes rhizome, 180 parts of schizonepeta, 180 parts of cacumen biotae, 180 parts of raspberry, 120 parts of rhizoma cyperi processed, 80 parts of honey-fried licorice root, stir-baked CORTEX EUCOMMIAE 180 Part, 180 parts of Poria cocos, 180 parts of teasel root, 80 parts of sucrose, 0.002 part of potassium sorbate;
Its preparation process is:
(1)Raw material Radix Angelicae Sinensis, the root of herbaceous peony, fructus corni, raspberry is taken to be pulverized, grinding particle size is 30-50 mesh, obtains raw material powder, standby;
(2)Take raw material donkey-hide gelatin, donkey-hide gelatin is milled to powder, granularity is 80-150 mesh, be placed in container and add opening of its weight 3-5 times amount After water, container is put into water proof heating in steamer and steams 25-65 minute, until donkey-hide gelatin dissolves, obtain donkey-hide gelatin dissolving liquid, standby;
(3)Take raw material Radix Codonopsis, parasitic loranthus, the Radix Astragali, the bighead atractylodes rhizome, schizonepeta, cacumen biotae, prepared rhizome of rehmannia, charred RADIX SANGUISORBAE, rhizoma cyperi processed, honey-fried licorice root, stir-fry The bark of eucommia, Poria cocos, teasel root are pulverized, and grinding particle size is 80-100 mesh, obtains raw material powder, standby;
(4)By step(1)Gained raw material powder and step(3)Gained original powder mixing and water adding decocts three after soaking 0.5-0.9 hour Secondary, add the 6-10 times amount decocting of raw material gross weight to boil 0.5-0.9 hour for the first time, pour out liquid, add for second raw material total The 6-10 times amount decocting of weight boils 0.5-0.9 hour, pours out liquid, and third time adds the 6-10 times amount decocting of raw material gross weight to boil 0.5-0.9 hour, merges three liquids, stands 8-12 hour, filters, and filtrate reduced in volume becomes 40-60 DEG C of survey relative density 1.02-1.15 medicinal extract, standby;
(5)By step(4)Middle gained medicinal extract and step(2)Gained donkey-hide gelatin dissolving liquid mixes, and adds the 2.5-5.5 of mixed liquor weight The purified water of times amount, stirring 15-30 minute, so as to be sufficiently mixed, carries out reduced pressure concentration to liquid, and thickening temperature is 60-65 DEG C, Steam pressure is 0.025-0.035Mpa, and vacuum is 0.065-0.085Mpa, controls relative density of medicine liquid in 1.25-1.35, Form concentration of liquid medicine liquid, standby;
(6)By step(5)Middle gained concentration of liquid medicine liquid adds the purified water of the 2.5-5.5 times amount of weight, adds sucrose and mountain Potassium sorbate, is heated to seething with excitement, stirs 10-20 minute, and micro-boiling rises insulation 10-20 minute, is filtered using centrifuge, is cooled to Room temperature, filling with clear glass bottle, irradiate the sterilizing of 20-40 minute, packaging under uviol lamp, obtain final product the Chinese medicine for the treatment of deficiency of qi and blood Composition.
Usage:Oral, 2 times a day, each 15ml.
Embodiment 2
A kind of Chinese medicine composition treating deficiency of qi and blood, is made up of the raw material of following weight portion:150 parts of Radix Angelicae Sinensis, 200 parts of the root of herbaceous peony, 200 parts of prepared rhizome of rehmannia, 200 parts of charred RADIX SANGUISORBAE, 200 parts of fructus corni, 150 parts of donkey-hide gelatin, 300 parts of Radix Codonopsis, 300 parts of parasitic loranthus, 500 parts of the Radix Astragali, 150 parts of the bighead atractylodes rhizome, 150 parts of schizonepeta, 150 parts of cacumen biotae, 150 parts of raspberry, 90 parts of rhizoma cyperi processed, 60 parts of honey-fried licorice root, stir-baked CORTEX EUCOMMIAE 150 Part, 150 parts of Poria cocos, 150 parts of teasel root, 70 parts of sucrose, 0.0015 part of potassium sorbate;
Its preparation process is:
(1)Raw material Radix Angelicae Sinensis, the root of herbaceous peony, fructus corni, raspberry is taken to be pulverized, grinding particle size is 30-50 mesh, obtains raw material powder, standby;
(2)Take raw material donkey-hide gelatin, donkey-hide gelatin is milled to powder, granularity is 80-150 mesh, be placed in container and add opening of its weight 3-5 times amount After water, container is put into water proof heating in steamer and steams 25-65 minute, until donkey-hide gelatin dissolves, obtain donkey-hide gelatin dissolving liquid, standby;
(3)Take raw material Radix Codonopsis, parasitic loranthus, the Radix Astragali, the bighead atractylodes rhizome, schizonepeta, cacumen biotae, prepared rhizome of rehmannia, charred RADIX SANGUISORBAE, rhizoma cyperi processed, honey-fried licorice root, stir-fry The bark of eucommia, Poria cocos, teasel root are pulverized, and grinding particle size is 80-100 mesh, obtains raw material powder, standby;
(4)By step(1)Gained raw material powder and step(3)Gained original powder mixing and water adding decocts three after soaking 0.5-0.9 hour Secondary, add the 6-10 times amount decocting of raw material gross weight to boil 0.5-0.9 hour for the first time, pour out liquid, add for second raw material total The 6-10 times amount decocting of weight boils 0.5-0.9 hour, pours out liquid, and third time adds the 6-10 times amount decocting of raw material gross weight to boil 0.5-0.9 hour, merges three liquids, stands 8-12 hour, filters, and filtrate reduced in volume becomes 40-60 DEG C of survey relative density 1.02-1.15 medicinal extract, standby;
(5)By step(4)Middle gained medicinal extract and step(2)Gained donkey-hide gelatin dissolving liquid mixes, and adds the 2.5-5.5 of mixed liquor weight The purified water of times amount, stirring 15-30 minute, so as to be sufficiently mixed, carries out reduced pressure concentration to liquid, and thickening temperature is 60-65 DEG C, Steam pressure is 0.025-0.035Mpa, and vacuum is 0.065-0.085Mpa, controls relative density of medicine liquid in 1.25-1.35, Form concentration of liquid medicine liquid, standby;
(6)By step(5)Middle gained concentration of liquid medicine liquid adds the purified water of the 2.5-5.5 times amount of weight, adds sucrose and mountain Potassium sorbate, is heated to seething with excitement, stirs 10-20 minute, and micro-boiling rises insulation 10-20 minute, is filtered using centrifuge, is cooled to Room temperature, filling with clear glass bottle, irradiate the sterilizing of 20-40 minute, packaging under uviol lamp, obtain final product the Chinese medicine for the treatment of deficiency of qi and blood Composition.
Usage:Oral, 2 times a day, each 15ml.
Embodiment 3
A kind of Chinese medicine composition treating deficiency of qi and blood, is made up of the raw material of following weight portion:120 parts of Radix Angelicae Sinensis, 170 parts of the root of herbaceous peony, 170 parts of prepared rhizome of rehmannia, 170 parts of charred RADIX SANGUISORBAE, 170 parts of fructus corni, 120 parts of donkey-hide gelatin, 200 parts of Radix Codonopsis, 200 parts of parasitic loranthus, 400 parts of the Radix Astragali, 120 parts of the bighead atractylodes rhizome, 120 parts of schizonepeta, 120 parts of cacumen biotae, 120 parts of raspberry, 60 parts of rhizoma cyperi processed, 40 parts of honey-fried licorice root, stir-baked CORTEX EUCOMMIAE 120 Part, 120 parts of Poria cocos, 120 parts of teasel root, 60 parts of sucrose, 0.001 part of potassium sorbate;
Its preparation process is:
(1)Raw material Radix Angelicae Sinensis, the root of herbaceous peony, fructus corni, raspberry is taken to be pulverized, grinding particle size is 30-50 mesh, obtains raw material powder, standby;
(2)Take raw material donkey-hide gelatin, donkey-hide gelatin is milled to powder, granularity is 80-150 mesh, be placed in container and add opening of its weight 3-5 times amount After water, container is put into water proof heating in steamer and steams 25-65 minute, until donkey-hide gelatin dissolves, obtain donkey-hide gelatin dissolving liquid, standby;
(3)Take raw material Radix Codonopsis, parasitic loranthus, the Radix Astragali, the bighead atractylodes rhizome, schizonepeta, cacumen biotae, prepared rhizome of rehmannia, charred RADIX SANGUISORBAE, rhizoma cyperi processed, honey-fried licorice root, stir-fry The bark of eucommia, Poria cocos, teasel root are pulverized, and grinding particle size is 80-100 mesh, obtains raw material powder, standby;
(4)By step(1)Gained raw material powder and step(3)Gained original powder mixing and water adding decocts three after soaking 0.5-0.9 hour Secondary, add the 6-10 times amount decocting of raw material gross weight to boil 0.5-0.9 hour for the first time, pour out liquid, add for second raw material total The 6-10 times amount decocting of weight boils 0.5-0.9 hour, pours out liquid, and third time adds the 6-10 times amount decocting of raw material gross weight to boil 0.5-0.9 hour, merges three liquids, stands 8-12 hour, filters, and filtrate reduced in volume becomes 40-60 DEG C of survey relative density 1.02-1.15 medicinal extract, standby;
(5)By step(4)Middle gained medicinal extract and step(2)Gained donkey-hide gelatin dissolving liquid mixes, and adds the 2.5-5.5 of mixed liquor weight The purified water of times amount, stirring 15-30 minute, so as to be sufficiently mixed, carries out reduced pressure concentration to liquid, and thickening temperature is 60-65 DEG C, Steam pressure is 0.025-0.035Mpa, and vacuum is 0.065-0.085Mpa, controls relative density of medicine liquid in 1.25-1.35, Form concentration of liquid medicine liquid, standby;
(6)By step(5)Middle gained concentration of liquid medicine liquid adds the purified water of the 2.5-5.5 times amount of weight, adds sucrose and mountain Potassium sorbate, is heated to seething with excitement, stirs 10-20 minute, and micro-boiling rises insulation 10-20 minute, is filtered using centrifuge, is cooled to Room temperature, filling with clear glass bottle, irradiate the sterilizing of 20-40 minute, packaging under uviol lamp, obtain final product the Chinese medicine for the treatment of deficiency of qi and blood Composition.
Usage:Oral, 2 times a day, each 15ml.
Traditional Chinese medicine composition for treating of the present invention observes asthenia of qi and blood patient 40, and clinical report is as follows:
1st, physical data
Clinical observation asthenia of qi and blood patient 40, age 19-60 year, average age 39.5 years old;
2nd, diagnostic criteria
Disease:Deficiency of qi and blood, body loses supports, with spiritlessness and weakness, the lazy speech of shortness of breath, pale white complexion or sallow, have a dizzy spell, lip and nail color Light, palpitation and insomnia, tongue is weak weak pulse etc. is the syndrome of common disease.
3rd, treatment method
Using traditional Chinese medicine composition for treating of the present invention, take traditional Chinese medicine oral liquid of the present invention, 2 times a day, each 15ml, it is one within 7 days The course for the treatment of.
4th, efficacy determination
Cure:Symptom disappears;
Effectively:Clinical symptom relief;
Invalid:Clinical symptoms are no improved or are increased.
5th, treatment results
In clinical treatment asthenia of qi and blood patient 40, cure 35 and account for 87.5%, effective 5 account for 12.5%, invalid 0, total effective rate For 100%.
6th, model case
Case 1:Female, 29 years old, it was continuous constantly closely leukorrhea over the past half year, sallow complexion, refreshing tired weak, deficiency of QI with disinclination to talk, receive few just Half congealed, abdominal distension, profuse leukorrhea color white matter is dilute, odorless, pale tongue with white fur, and arteries and veins delays weak, is diagnosed as:Deficiency of qi and blood, takes in the present invention One course for the treatment of of medicine oral liquid, patient symptom substantially mitigates, and takes two courses for the treatment of of traditional Chinese medicine oral liquid of the present invention again, and symptom is substantially good Turn, take two courses for the treatment of of traditional Chinese medicine oral liquid of the present invention, all symptoms are wholly absent again, recovery from illness, follow-up after half a year is no recurred.
Case 2:Female, 35 years old, menstrual period, amount was few, and back is aching and limp, spiritlessness and weakness too long, the lazy speech of shortness of breath, poor appetite, colourless Simple and unadorned, pale tongue with moistness, weak pulse, it is diagnosed as:Deficiency of qi and blood, takes one course for the treatment of of traditional Chinese medicine oral liquid of the present invention, and patient symptom is obvious Mitigate, take two courses for the treatment of of traditional Chinese medicine oral liquid of the present invention, symptom is clearly better again, take two treatments of traditional Chinese medicine oral liquid of the present invention again Journey, all symptoms are wholly absent, recovery from illness, and follow-up after half a year is no recurred.
Case 3:Female, 30 years old, has scleroma above Finding case right breast, alactation is smooth, and it is invalid voluntarily to massage, gradually Red and swollen heat pain phenomenon occurs, with seeing fever with aversion to cold, bodily pain, spontaneous perspiration, poor appetite, dry and hard excrement, red tongue body, tongue is thin slightly yellow, arteries and veins Imaginary number, is diagnosed as:Deficiency of qi and blood, takes one course for the treatment of of traditional Chinese medicine oral liquid of the present invention, patient symptom substantially mitigates, and takes this again Bright two courses for the treatment of of traditional Chinese medicine oral liquid, symptom is clearly better, and takes two courses for the treatment of of traditional Chinese medicine oral liquid of the present invention again, and all symptoms are complete Disappear, recovery from illness, follow-up after half a year is no recurred.
Above the present invention is described in detail, the explanation of embodiment be only intended to help understand the method for the present invention and Its core concept, its object is to allow the personage being familiar with this art will appreciate that present disclosure and to implement according to this, and Can not be limited the scope of the invention with this;All equivalence changes made according to spirit of the invention or modification, all should contain Cover within protection scope of the present invention.

Claims (6)

1. a kind of Chinese medicine composition treating deficiency of qi and blood and preparation method it is characterised in that:Raw material system by following weight portion Become:Radix Angelicae Sinensis 120-180 part, root of herbaceous peony 170-230 part, prepared rhizome of rehmannia 170-230 part, charred RADIX SANGUISORBAE 170-230 part, fructus corni 170-230 part, Donkey-hide gelatin 120-180 part, Radix Codonopsis 200-400 part, parasitic loranthus 200-400 part, Radix Astragali 400-600 part, bighead atractylodes rhizome 120-180 part, schizonepeta 120-180 part, cacumen biotae 120-180 part, raspberry 120-180 part, rhizoma cyperi 60-120 part processed, honey-fried licorice root 40-80 part, stir-baked CORTEX EUCOMMIAE 120-180 part, Poria cocos 120-180 part, teasel root 120-180 part, sucrose 60-80 part, potassium sorbate 0.001-0.002 part.
2. a kind of Chinese medicine composition treating deficiency of qi and blood according to claim 1 preparation method it is characterised in that:Its Preparation process is:
(1)Raw material Radix Angelicae Sinensis, the root of herbaceous peony, fructus corni, raspberry is taken to be pulverized, grinding particle size is 30-50 mesh, obtains raw material powder, standby;
(2)Take raw material donkey-hide gelatin, donkey-hide gelatin is milled to powder, granularity is 80-150 mesh, be placed in container and add opening of its weight 3-5 times amount After water, container is put into water proof heating in steamer and steams 25-65 minute, until donkey-hide gelatin dissolves, obtain donkey-hide gelatin dissolving liquid, standby;
(3)Take raw material Radix Codonopsis, parasitic loranthus, the Radix Astragali, the bighead atractylodes rhizome, schizonepeta, cacumen biotae, prepared rhizome of rehmannia, charred RADIX SANGUISORBAE, rhizoma cyperi processed, honey-fried licorice root, stir-fry The bark of eucommia, Poria cocos, teasel root are pulverized, and grinding particle size is 80-100 mesh, obtains raw material powder, standby;
(4)By step(1)Gained raw material powder and step(3)Gained original powder mixing and water adding decocts three after soaking 0.5-0.9 hour Secondary, add the 6-10 times amount decocting of raw material gross weight to boil 0.5-0.9 hour for the first time, pour out liquid, add for second raw material total The 6-10 times amount decocting of weight boils 0.5-0.9 hour, pours out liquid, and third time adds the 6-10 times amount decocting of raw material gross weight to boil 0.5-0.9 hour, merges three liquids, stands 8-12 hour, filters, and filtrate reduced in volume becomes 40-60 DEG C of survey relative density 1.02-1.15 medicinal extract, standby;
(5)By step(4)Middle gained medicinal extract and step(2)Gained donkey-hide gelatin dissolving liquid mixes, and adds the 2.5-5.5 of mixed liquor weight The purified water of times amount, stirring 15-30 minute, so as to be sufficiently mixed, carries out reduced pressure concentration to liquid, and thickening temperature is 60-65 DEG C, Steam pressure is 0.025-0.035Mpa, and vacuum is 0.065-0.085Mpa, controls relative density of medicine liquid in 1.25-1.35, Form concentration of liquid medicine liquid, standby;
(6)By step(5)Middle gained concentration of liquid medicine liquid adds the purified water of the 2.5-5.5 times amount of weight, adds sucrose and mountain Potassium sorbate, is heated to seething with excitement, stirs 10-20 minute, and micro-boiling rises insulation 10-20 minute, is filtered using centrifuge, is cooled to Room temperature, filling with clear glass bottle, irradiate the sterilizing of 20-40 minute, packaging under uviol lamp, obtain final product the Chinese medicine for the treatment of deficiency of qi and blood Composition.
3. a kind of Chinese medicine composition treating deficiency of qi and blood according to claim 2 preparation method it is characterised in that:Its Preparation process is:
(1)Raw material Radix Angelicae Sinensis, the root of herbaceous peony, fructus corni, raspberry is taken to be pulverized, grinding particle size is 50 mesh, obtains raw material powder, standby;
(2)Take raw material donkey-hide gelatin, donkey-hide gelatin be milled to powder, granularity is 80 mesh, be placed in container plus after the boiling water of its weight 5 times amount, Container is put into water proof heating in steamer steam 45 minutes, until donkey-hide gelatin dissolves, obtain donkey-hide gelatin dissolving liquid, standby;
(3)Take raw material Radix Codonopsis, parasitic loranthus, the Radix Astragali, the bighead atractylodes rhizome, schizonepeta, cacumen biotae, prepared rhizome of rehmannia, charred RADIX SANGUISORBAE, rhizoma cyperi processed, honey-fried licorice root, stir-fry The bark of eucommia, Poria cocos, teasel root are pulverized, and grinding particle size is 80 mesh, obtains raw material powder, standby;
(4)By step(1)Gained raw material powder and step(3)Gained original powder mixing and water adding decocts three times after soaking 0.5 hour, the Once add 10 times amount decoctings of raw material gross weight to boil 0.7 hour, pour out liquid, 10 times amount that second adds raw material gross weight Decocting boils 0.7 hour, pours out liquid, and third time adds 10 times amount decoctings of raw material gross weight to boil 0.7 hour, merges three medicines Liquid, stands 8 hours, filters, and filtrate reduced in volume becomes the medicinal extract of 60 DEG C of survey relative densities 1.02, standby;
(5)By step(4)Middle gained medicinal extract and step(2)Gained donkey-hide gelatin dissolving liquid mixes, and adds 4 times amount of mixed liquor weight Purified water, stirring carries out reduced pressure concentration so as to be sufficiently mixed to liquid in 15 minutes, and thickening temperature is 65 DEG C, and steam pressure is 0.025Mpa, vacuum is 0.065Mpa, controls relative density of medicine liquid 1.25, forms concentration of liquid medicine liquid, standby;
(6)By step(5)Middle gained concentration of liquid medicine liquid adds the purified water of 4 times amount of weight, adds sucrose and potassium sorbate, It is heated to seething with excitement, stirs 10 minutes, micro-boiling rises insulation 10 minutes, is filtered using centrifuge, is cooled to room temperature, uses clean glass Glass bottle is filling, irradiates sterilizing in 35 minutes, packaging, obtain final product the Chinese medicine composition for the treatment of deficiency of qi and blood under uviol lamp.
4. a kind of Chinese medicine composition treating deficiency of qi and blood according to claim 1 it is characterised in that:By following weight portion Raw material make:150 parts of Radix Angelicae Sinensis, 200 parts of the root of herbaceous peony, 200 parts of prepared rhizome of rehmannia, 200 parts of charred RADIX SANGUISORBAE, 200 parts of fructus corni, 150 parts of donkey-hide gelatin, party 300 parts of ginseng, 300 parts of parasitic loranthus, 500 parts of the Radix Astragali, 150 parts of the bighead atractylodes rhizome, 150 parts of schizonepeta, 150 parts of cacumen biotae, 150 parts of raspberry, system 90 parts of rhizoma cyperi, 60 parts of honey-fried licorice root, 150 parts of stir-baked CORTEX EUCOMMIAE, 150 parts of Poria cocos, 150 parts of teasel root, 70 parts of sucrose, potassium sorbate 0.0015 Part.
5. a kind of Chinese medicine composition treating deficiency of qi and blood according to claim 1 it is characterised in that:By following weight portion Raw material make:180 parts of Radix Angelicae Sinensis, 230 parts of the root of herbaceous peony, 230 parts of prepared rhizome of rehmannia, 230 parts of charred RADIX SANGUISORBAE, 230 parts of fructus corni, 180 parts of donkey-hide gelatin, party 400 parts of ginseng, 400 parts of parasitic loranthus, 600 parts of the Radix Astragali, 180 parts of the bighead atractylodes rhizome, 180 parts of schizonepeta, 180 parts of cacumen biotae, 180 parts of raspberry, system 120 parts of rhizoma cyperi, 80 parts of honey-fried licorice root, 180 parts of stir-baked CORTEX EUCOMMIAE, 180 parts of Poria cocos, 180 parts of teasel root, 80 parts of sucrose, potassium sorbate 0.002 Part.
6. a kind of Chinese medicine composition treating deficiency of qi and blood according to claim 1 it is characterised in that:By following weight portion Raw material make:120 parts of Radix Angelicae Sinensis, 170 parts of the root of herbaceous peony, 170 parts of prepared rhizome of rehmannia, 170 parts of charred RADIX SANGUISORBAE, 170 parts of fructus corni, 120 parts of donkey-hide gelatin, party 200 parts of ginseng, 200 parts of parasitic loranthus, 400 parts of the Radix Astragali, 120 parts of the bighead atractylodes rhizome, 120 parts of schizonepeta, 120 parts of cacumen biotae, 120 parts of raspberry, system 60 parts of rhizoma cyperi, 40 parts of honey-fried licorice root, 120 parts of stir-baked CORTEX EUCOMMIAE, 120 parts of Poria cocos, 120 parts of teasel root, 60 parts of sucrose, 0.001 part of potassium sorbate.
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CN106729160A (en) * 2017-03-08 2017-05-31 汪凯源 A kind of health food granule of strengthen immunity and preparation method thereof

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Title
谭科: "《读经典、学中医、修医德 学习四大经典 传承中医文化》", 30 September 2001, 湖北省秭归县卫生局 *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106729160A (en) * 2017-03-08 2017-05-31 汪凯源 A kind of health food granule of strengthen immunity and preparation method thereof

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Application publication date: 20170208