CN106492125A - A kind of treat medicine of coronary heart disease and preparation method thereof - Google Patents

A kind of treat medicine of coronary heart disease and preparation method thereof Download PDF

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CN106492125A
CN106492125A CN201611129777.3A CN201611129777A CN106492125A CN 106492125 A CN106492125 A CN 106492125A CN 201611129777 A CN201611129777 A CN 201611129777A CN 106492125 A CN106492125 A CN 106492125A
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冉兆斌
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    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
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    • A61K36/537Salvia (sage)
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    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/24Mucus; Mucous glands; Bursa; Synovial fluid; Arthral fluid; Excreta; Spinal fluid
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Abstract

The invention discloses a kind of treat medicine of coronary heart disease and preparation method thereof, which is mainly prepared from according to a certain weight ratio by the red sage root, the fruit of Chinese magnoliavine, the tuber of dwarf lilyturf, polyporus lucidus, the root of herbaceous peony, root tuber of aromatic turmeric, hawthorn, radix pseudostellariae, Buddha's hand, honeysuckle, radix rehmanniae recen, caulis bambusae in taenian, ilex pubescens, paniculate swallowwort, Fructus Aurantii, barrenwort, radix polygonati officinalis, safflower, arillus longan, excrementum pteropi, fushen, rush, medicine of the present invention has nourishing yin to moisten dryness, promoting blood circulation, benefiting blood and regulating blood circulation, the function of slit phlegm qi-regulating, for treating coronary heart disease instant effect, good effect, do not recur.

Description

A kind of treat medicine of coronary heart disease and preparation method thereof
Technical field
The present invention relates to a kind of treat medicine of coronary heart disease and preparation method thereof, belong to the field of Chinese medicines.
Background technology
Coronary heart disease is that coronary artery occurs atherosclerotic lesion and causes lumen of vessels stenosis or occlusion, causes the heart Myocardial ischemia, anoxic or downright bad and caused heart disease, but the scope of coronary heart disease more extensively may also include inflammation, embolism etc. Cause luminal stenosis or obturation.The traditional Chinese medical science then thinks coronary heart disease and insufficiency of vital energy and blood, and negative and positive virtual loss, qi deficiency to blood stasis, phlegm stagnation in collateral are relevant. Due to western medicine large side effects, therefore there is great demand to the Chinese medicine of effectively treatment coronary heart disease in people, so far for Only, it has not been found that with regard to relevant report of the invention.
Content of the invention
The present inventor have found effectively treatment coronary disease finally according to the research and the checking repeatedly of clinical testing of theory of traditional Chinese medical science The medicine of disease, so that complete the present invention.
It is an object of the invention to provide a kind of Chinese medicine composition of effectively treatment coronary heart disease.
Another object of the present invention just there is provided the preparation method of the Chinese medicine composition.
Medicine of the present invention is to select the red sage root, the fruit of Chinese magnoliavine, the tuber of dwarf lilyturf, polyporus lucidus, the root of herbaceous peony, root tuber of aromatic turmeric, hawthorn, radix pseudostellariae, Buddha's hand, gold Honeysuckle flower, radix rehmanniae recen, caulis bambusae in taenian, ilex pubescens, paniculate swallowwort, Fructus Aurantii, barrenwort, radix polygonati officinalis, safflower, arillus longan, excrementum pteropi, polygala root, the root of Dahurain angelica, Myrrh, sophora flower, perilla seed, grass-leaved sweetflag, radix bupleuri, fushen, rush, radish seed, Japanese ardisia, cassia twig, Radix Angelicae Sinensis are combined preparation , cause each efficacy of drugs to produce synergy these drug regimens such that it is able to effectively treatment coronary heart disease.Wherein from pellet Ginseng is because that its nature and flavor is bitter, and tepor, enter the heart, Liver Channel have blood circulation and promoting silt, calming heart and tranquilizing mind, apocenosis, the function of pain relieving to control angina pectoris, Irregular menstruation, dysmenorrhoea, to close, metrorrhagia under band, lump in the abdomen, accumulation, abdominal pain due to blood stasis, arthralgia, shock palpitation not sleep, malignant sore swollen drug.Choosing It is because that its nature and flavor acid, temperature enter lung, kidney channel, astringes the lung with the fruit of Chinese magnoliavine, nourshing kidney is promoted the production of body fluid, receives sweat, the function of puckery essence is controlled the deficiency syndrome of the lung and breathed heavily Cough, dry is made yearningly, and spontaneous perspiration, night sweat, internal lesion caused by overexertion are thin thin, emission, protracted dysentery and diarrhea.Its property sweet and slightly bitter taste is because from the tuber of dwarf lilyturf, Cold, enter lung, stomach, the heart channel of Hang-Shaoyin, have Yin nourishing and lung moistening, relieving restlessness that clears away heart-fire, the function of reinforcing stomach reg fluid to control dryness of the lung dry cough, spit blood, spitting of blood, consumptive lung disease, Lung carbuncle, consumptive disease dysphoria with smothery sensation, clear thirsty, pyreticosis Tianjin is hindered, dry throat, constipation.It is because that its nature and flavor is sweet from polyporus lucidus, puts down, have tonifying Qi Calm the nerves, relieving cough and asthma function controls dizziness egersis, palpitation, consumptive disease cough and asthma.Its nature and flavor picric acid is because from the root of herbaceous peony, cool, Enter liver, the spleen channel, have nourishing blood and liver, pain relieving in delaying, and hold back the cloudy function of receiving sweat, control chest and abdomen pain over the hypochondriac region, and diarrhea dysentery abdominal pain, spontaneous perspiration are stolen Sweat, fever due to yin deficiency, irregular menstruation, uterine bleeding, under band.It is because that its nature and flavor is worked hard from root tuber of aromatic turmeric, cool, enter the heart, lung, Liver Channel have row Gas solution is with the function of cool blood broken stasis of blood controls all pains of chest and abdomen side of body rib, and the mistake heart is demented, and pyreticosis coma is spitted blood, bleeding from five sense organs or subcutaneous tissue, hematuria, blood strangury, woman Female's vicarious menstruation, jaundice.It is because that its nature and flavor acid is sweet from hawthorn, tepor enters spleen, stomach, Liver Channel, has digestion gathered food, scattered blood stasis, expelling tenia Function, control meat product, lump in the abdomen, phlegm and retained fluid, feeling of fullness, acid regurgitation, rush down dysentery, intestines wind, pain in the back, hernia, postpartum postpartum abdominal pain, lochiorrhagia are little Youngster's breast food is stagnated.It is because that its nature and flavor sweetness and bitterness, tepor, enter the heart, spleen, lung three are passed through from radix pseudostellariae, has the function of tonifying lung, invigorating the spleen, Control cough due to deficiency of the lung, spleen eating less, palpitaition mesh sweat, metal fatigue.The arduous acid of its nature and flavor, temperature, enter liver, stomach are because from Buddha's hand Through having qi-regulating, the function of resolving sputum to treat for stomachache, coercing swollen, vomiting, dysphagic, phlegm and retained fluid cough and asthma, and can relieve the effect of alcohol.It is because from honeysuckle Its nature and flavor is sweet, trembles with fear, enters lung, stomach, have heat-clearing, the function of removing toxic substances to control warm disease heating, toxic-heat and blood stasis, large carbuncle, pyogenic infections, scrofula, hemorrhoid Leakage.It is because that its nature and flavor is sweet from radix rehmanniae recen, trembles with fear, the thoughts of returning home, liver and kidney channel has clearing heat and cooling blood, yin-nourishing, the function of promoting the production of body fluid to control pyreticosis Polydipsia, yin asthenia generating intrinsic heat, hectic fever due to yin labor heat, Heat Diabetes are spitted blood, bleeding from five sense organs or subcutaneous tissue, spot dermexanthesis.It is because that its nature and flavor is sweet from caulis bambusae in taenian, cool, Enter stomach, gallbladder channel, have heat-clearing, cool blood, resolving sputum, the function of antiemetic to control dysphoria with smothery sensation vomiting, hiccup, the hot cough and asthma of phlegm is spitted blood, and bleeding from five sense organs or subcutaneous tissue collapses Leakage, vomiting during early pregnancy, movement of the foetus are shied.It is because that its nature and flavor slight bitter is sweet from ilex pubescens, mild-natured, nontoxic, there is clearing heat and detoxicating, blood circulation and channel invigorating Function, control anemopyretic cold, dyspnea and cough due to lung-heat, laryngeal edema, tonsillitis, dysentery, coronary heart disease are inclined caused by cerebrovas-cularaccident Paralysis, Buerger's disease, erysipelas are scalded, central retinitis, uveitis, and skin acute suppurative inflammation. It is because that its nature and flavor is pungent from paniculate swallowwort, temperature has analgesia, cough-relieving, inducing diuresis for removing edema, the function of promoting blood circulation and detoxication to treat for stomachache, and has a toothache, Rheumatalgia pain, bellyache in menstrual period, chronic bronchitis, ascites, oedema, dysentery, enteritis, traumatic injury, eczema, nettle rash, poisonous snake are stung Wound.Its nature and flavor toil, cool is because from Fructus Aurantii.Enter lung, spleen, large intestine channel.Relieving stagnant Qi, row phlegm, disappear product.Control chest diaphragm phlegm stagnant, the feeling of stuffiness in chest, Swollen, dyspepsia is coerced, gas is vomitted inverse, weight, prolapse of the anus, the prolapse of uterus after diarrhea.Its property acrid-sweet flavor is because from barrenwort, temperature enters Liver and kidney channel, has tonifying kidney and strengthening yang, the function of dispelling wind and eliminating dampness to control impotence and do not lift, dribbling urination, muscles and bones contraction urgency, hemiplegia, waist and knee Powerless, arthralgia due to wind-dampness, four pin are meciless.It is because that its nature and flavor is sweet from radix polygonati officinalis, puts down, enter lung, stomach has yin-nourishing, moisturizes, relieving restlessness, The function of quenching the thirst, controls pyreticosis sun wound, and cough, polydipsia, deficient fever, the paddy that disappears are easily hungry, frequent urination.Its property is because from safflower Taste is pungent, temperature, enter the heart, Liver Channel have invigorate blood circulation, the function of stasis eliminatings pain relieving, controlling through closing, lump in the abdomen to have difficult labour, stillborn foetus, and lochia is not OK, hemostasis is had a pain, carbuncle swells, injury from falling down.It is because that its nature and flavor is sweet from arillus longan, temperature, enter the heart, the spleen channel have heart-spleen boosting, tonifying Qi Blood, the function of calming the nerves, it is thin and weak to control virtual work, insomnia, forgetful, and palpitation with fear is seized with terror secondary.Its nature and flavor bitter sweet is because from excrementum pteropi, temperature enters Liver, the spleen channel, the life function of having promoting circulation of blood pain relieving, control all pains of trusted subordinate's vim and vigour, and women's Amenorrhea, postpartum blood stasis are had a pain;Control outward snake, scorpion, Centipde-bite, stir-fry stop blooding, and control metrorrhagia, and menorrhagia, and leukorrhea with bloody discharge is without cease.Its nature and flavor toil is because from polygala root, temperature enters The heart, kidney channel, have tranquilize the mind and promote the intelligence, eliminating the phlegm, the function of Xie Yu to control palpitation with fear, forgetful, nocturnal emission, insomnia, cough ant phlegm, ulcer sore swells.Choosing It is because that its nature and flavor is pungent with the root of Dahurain angelica, temperature enters lung, spleen, stomach, has wind-dispelling, eliminating dampness, detumescence, the function of pain relieving to control headache, eyebrow rib Ostalgia, dentalgia, nasosinusitis, cold-dampness stomachache, intestines wind anal fistula, leukorrhea with reddish discharge, ulcer sores, skin is dry itches, mange.From myrrh be because Bitter for its nature and flavor, put down, enter Liver Channel, have scattered blood stasis eliminatings, the function of detumescence ding-tong to control and fall damage, metal-inflicted wound, muscles and bones, all pains of trusted subordinate, Lump in the abdomen, Amenorrhea, ulcer sore pain, anal fistula, mesh hinder.It is because that its nature and flavor is bitter from sophora flower, cool, enter liver, large intestine channel have a heat-clearing, cool blood, The function of hemostasis, controls hematochezia, hemorrhoid blood, hematuria, blood strangury, uterine bleeding, bleeding from five sense organs or subcutaneous tissue, under dysentery, wind-heat hot eyes, and skin sore, and For prevention of stroke.It is because that its nature and flavor is pungent from perilla seed, temperature enters lung, large intestine channel, has lower gas, dissolving phlegm, moistening lung, wide intestines Function, controls and coughs inverse, asthma due to excessive phlegm, the stagnation of the circulation of vital energy, constipation.It is because that its nature and flavor is worked hard from grass-leaved sweetflag, tepor, enter the heart, liver, the spleen channel have out Key, slit phlegm, qi-regulating, promoting blood circulation dissipate wind, and the function of drying controls insane, coma due to blocking of the respiratory system, and pyreticosis coma, forgetful, deafness with qi stagnation, ambition are tired of Vexed, stomachache, stomachache, wind-cold-dampness arthralgia, swollen ulcer drug, traumatic injury.It is because that its nature and flavor is bitter from radix bupleuri, cool, enter liver, gallbladder channel, In having and inducing sweat, soothing the liver, the function of rising Yang controls fevers and chills alternate, and fullness in the chest and hypochondriac pain, bitter taste are deaf, headache and dizziness, malaria, and lower profit is de- Anus, irregular menstruation, metroptosis.Its property slightly sweet flavor is because from fushen, is put down, enter the heart, the spleen channel have calming heart, calm the nerves, Li Shui's Function, controls palpitation with fear of having a guilty conscience, forgetful, insomnia, shies, difficult urination.Its property slightly sweet flavor is because from rush, is trembled with fear, enter the heart, Lung, small intestinl channel, have clearing heart fire, the function of inducing diuresis for treating strangurtia to control gonorrhoea, and oedema, difficult urination, jaundice with damp-heat pathogen, dysphoria and insomnia are little Youngster's morbid night crying of babies, larynx numbness, wound.Its property acrid-sweet flavor is because from radish seed, is put down, is entered lung, stomach, have lower gas Dingchuan, eliminate indigestion and phlegm Function, control cough asthma due to excessive phlegm, stagnation of QI due to dyspepsia, abdominal distension uncomfortable in chest, weight after diarrhea.It is because that its nature and flavor is pungent from Japanese ardisia, slight bitter is returned Lung, Liver Channel, have expelling phlegm and arresting coughing, clearing damp and promoting diuresis, the function of promoting blood circulation to control new chronic cough and cough, blood-stained sputum, jaundice with damp-heat pathogen, bruise Damage.Its property acrid-sweet flavor is because from cassia twig, temperature enters bladder, the heart, lung channel, has sweating expelling pathogenic factors from muscles and skin, the function of warming meridians and promoting circulation of qi to control Exterior syndrome due to wind-cold, shoulder back of the body podomere ache, obstruction of qi in the chest phlegm and retained fluid, Amenorrhea lump in the abdomen.
Specific embodiment
The drug dose of instant component is also that inventor is drawn through groping in a large number to summarize, and the consumption of each component is following heavy All there is in the range of amount preferable curative effect:
15-25 gram of the red sage root, 10-20 gram of the fruit of Chinese magnoliavine, 5-15 gram of the tuber of dwarf lilyturf, 10-20 gram of polyporus lucidus, 10-20 gram of the root of herbaceous peony, root tuber of aromatic turmeric 5-15 Gram, 10-15 gram of hawthorn, 7-12 gram of radix pseudostellariae, 5-10 gram of Buddha's hand, 10-15 gram of honeysuckle, 10-15 gram of radix rehmanniae recen, caulis bambusae in taenian 5-15 Gram, 10-20 gram of ilex pubescens, 10-20 gram of paniculate swallowwort, 5-15 gram of Fructus Aurantii, 10-20 gram of barrenwort, 10-15 gram of radix polygonati officinalis, safflower 5-15 Gram, 10-20 gram of arillus longan, 7-12 gram of excrementum pteropi, polygala root 5-15 gram, 5-15 gram of the root of Dahurain angelica, 5-15 gram of myrrh, 5-15 gram of sophora flower are purple Perillaseed 10-20 gram, 5-15 gram of grass-leaved sweetflag, 10-20 gram of radix bupleuri, 5-15 gram of fushen, 10-20 gram of rush, 10-15 gram of radish seed, 5-15 gram of Japanese ardisia, 5-15 gram of cassia twig, 15-25 gram of Radix Angelicae Sinensis.
Preferably:
20 grams of the red sage root, 15 grams of the fruit of Chinese magnoliavine, 10 grams of the tuber of dwarf lilyturf, 15 grams of polyporus lucidus, 15 grams of the root of herbaceous peony, 10 grams of root tuber of aromatic turmeric, 12 grams of hawthorn, radix pseudostellariae 9 grams, 8 grams of Buddha's hand, 12 grams of honeysuckle, 12 grams of radix rehmanniae recen, 10 grams of caulis bambusae in taenian, 15 grams of ilex pubescens, 15 grams of paniculate swallowwort, 10 grams of Fructus Aurantii are excessive 15 grams of the sheep leaves of pulse plants, 12 grams of radix polygonati officinalis, 10 grams of safflower, 15 grams of arillus longan, 9 grams of excrementum pteropi, 10 grams of polygala root, 10 grams of the root of Dahurain angelica, 10 grams of myrrh, Chinese scholartree 10 grams are spent, 15 grams of perilla seed, 10 grams of grass-leaved sweetflag, 15 grams of radix bupleuri, 10 grams of fushen, 15 grams of rush, 12 grams of radish seed, Japanese ardisia 10 Gram, 10 grams of cassia twig, 20 grams of Radix Angelicae Sinensis.
The preparation method of medicine of the present invention is as follows
First, get the raw materials ready
1st, the red sage root:Net impurity is picked, rhizome is removed, is cleaned, is pulled out, cut into slices after running through, dry;
2nd, the fruit of Chinese magnoliavine:Grey bits are weeded out, impurity is removed, is put in food steamer and is steamed thoroughly, taking-up is dried;
3rd, the tuber of dwarf lilyturf:Net impurity is picked, is soaked in water, pulled out, after running through, pump the heart, then cleaned and dry;
4th, polyporus lucidus:Impurity is removed, is cleaned, is softened, cut sheet, dried, weed out chip;
5th, the root of herbaceous peony:Impurity is picked, separates size, be soaked in water to eighty per cant thoroughly, pull out, solarization is dried in the air, moistened to inside and outside humidity uniformly, cut Piece, dries;
6th, root tuber of aromatic turmeric:It is soaked in water, cleans, pull solarization out and dry in the air, run through, cuts into slices, dry;
7th, hawthorn:Net impurity is picked, core is weeded out;
8th, radix pseudostellariae:Fibrous root is extractd, is dried;
9th, Buddha's hand:Impurity is picked, after being moistened with water spray, chopping is dried;
10th, honeysuckle:Silt is weeded out, net impurity is picked;
11st, radix rehmanniae recen:Crude drug is taken, impurity is removed, is cleaned, is slightly moistened, cut sheet, dried, weed out chip;
12nd, caulis bambusae in taenian:Hard bamboo let, impurity is removed, grey bits are shaked off, little group or segment is kneaded into;
13rd, ilex pubescens:Run through with water, segment is dried, weed out grey bits;
14th, paniculate swallowwort:Net impurity is picked, is cleaned, is run through, be cut into 1.5 centimetres of sections, dry;
15th, Fructus Aurantii:Flesh, core being removed, being cleaned, is slightly soaked, pull out, soften, doubling being pinched with hand, section is dried;
16th, barrenwort:Net impurity is picked, goes to obstruct, chopping weeds out chip;
17th, radix polygonati officinalis:Impurity is removed, soil is cleaned, vexed profit is uniform to inside and outside humidity, section is dried;
18th, safflower:Net impurity is picked, cauline leaf, base of a fruit head is removed, is dried;
19th, arillus longan:Crude drug is taken, impurity is removed;
20th, excrementum pteropi:Net impurity is picked, grey bits are smashed or weed out;
21st, polygala root:Impurity is picked, segment weeds out grey bits;
22nd, the root of Dahurain angelica:Pick net impurity, wash, soak, pull out and run through, slightly shine to crust without soapy feeling when, then after vexed profit, cut Piece is dried;
23rd, myrrh:Impurity is picked, fragment is broken into;
24th, sophora flower:Crude drug is taken, stalk, leaf and impurity is removed, is weeded out grey bits;
25 perilla seeds:Dedusting of winnowing with a dustpan is considered to be worth doing, is cleaned, is dried;
26th, grass-leaved sweetflag:Impurity is picked, is cleaned, is slightly soaked, run through, cut into slices, dry;
27th, radix bupleuri:Impurity is picked, residual stem is removed, silt is cleaned, is pulled out, cut into slices after running through in time, dried immediately;
28th, fushen:Crude drug is taken, impurity is removed, is cleaned, is run through, be cut into foursquare or block, dry in the shade;
29th, rush:Take rush to put in pot, the smaller pot of one bore of overlying, paste with blank sheet of paper, salt mudding is used in two pots of junctions Gu, do not make to lose heart, be calcined to blank sheet of paper and cease fire in coke yellow, take out after cooling completely;
30th, radish seed:Winnow with a dustpan decontamination, rinse soil, pull out, dry, the used time smashs to pieces;
31st, Japanese ardisia:Impurity is removed, is cleaned, is slightly moistened, segment, dried;
32nd, cassia twig:Slightly soaked with water, pulled out, vexed moisten to saturating, section is dried, weeds out bits;
33rd, Radix Angelicae Sinensis:Impurity is picked, is cleaned, vexed profit is slightly dried in the air, and section is dried.
2nd, prepare
1st, by processing after the red sage root, the fruit of Chinese magnoliavine, the tuber of dwarf lilyturf, polyporus lucidus, the root of herbaceous peony, root tuber of aromatic turmeric, hawthorn, radix pseudostellariae, Buddha's hand, honeysuckle, life Glutinous rehmannia, caulis bambusae in taenian, ilex pubescens, paniculate swallowwort, Fructus Aurantii, barrenwort, radix polygonati officinalis, safflower, arillus longan, excrementum pteropi, polygala root, the root of Dahurain angelica, myrrh, Chinese scholartree Flower, perilla seed, grass-leaved sweetflag, radix bupleuri, fushen, rush, radish seed, Japanese ardisia, cassia twig, Radix Angelicae Sinensis are put in decocting container, and first Secondary adding water 8 times is measured, and after soaking 100 minutes, fries by intense fire to boil and rises, then with being cooked by slow fire 20 minutes, filter to obtain first time decoction liquor, First time decoction liquor is poured in container;
2nd, the dregs of a decoction of filtration are added 6 times of amounts, is boiled by intense fire, then with being cooked by slow fire 20 minutes, filter to obtain second decoction liquor;
3rd, will decoction liquor mixing and stirring twice, be divided into 4 doses and take.
In prescription, the red sage root has blood circulation and promoting silt, calming heart and tranquilizing mind, pain relieving to control anginal function for monarch drug in a prescription;Radix polygonati officinalis yin-nourishing, profit Dry, relieving restlessness is quenched the thirst, and controls pyreticosis sun wound, cough, polydipsia, deficient fever;Radix Angelicae Sinensis has a benefiting blood and regulating blood circulation, menstruction regulating and pain relieving, moisturize laxation Function, the two is ministerial drug, and three taste medicines play nourishing yin to moisten dryness jointly, and blood circulation and promoting silt, benefiting blood and regulating blood circulation, calming heart and tranquilizing mind, pain relieving treat the heart The effect of angina, comprehensively, and with nourishing yin to moisten dryness, promoting blood circulation can effect a permanent cure based on benefiting blood and regulating blood circulation treatment coronary heart disease effect, arillus longan There is heart-spleen boosting, fill blood, the function of calming the nerves is adjutant, and grass-leaved sweetflag has has one's ideas straightened out, slit phlegm, qi-regulating, promoting blood circulation dissipates wind, the function of drying For making medicine, it is to take stopgap measures with remaining all medicines.
Medicine of the present invention has a nourishing yin to moisten dryness, promoting blood circulation, benefiting blood and regulating blood circulation, and the function of slit phlegm qi-regulating, for treating coronary disease Disease, short treating period, instant effect, non-relapse after healing.
The beneficial effect of medicine of the present invention is expanded on further below by way of test example, and these test examples include this The animal toxicity test report of bright medicine and clinical observation on the therapeutic effect data.
The animal toxicity test report of [test example 1] medicine of the present invention:
Rabbit 30 is taken, male and female dual-purpose, 2.0 2.5kg of body weight are divided to two groups, 15 per group, one of which is tested for overdose Group, another group is normal amount test group.Super quantity group is 20ml/kg, and normal amount is 10ml/kg, and administering mode is given for administration by gavage Medicine, twice daily, serve on 7 days, the reaction of observation administration daily, as a result shows that two groups of rabbit activities, diet are normal, and medicine is without bad Toxic and side effect.
The clinical observation on the therapeutic effect of [test example 2] medicine of the present invention
1st, physical data
Accept coronary heart disease out-patient totally 31 for medical treatment.
2nd, diagnostic criteria
Classical symptom be chest compression sensation of asphyxia, vexed swollen sense, violent burn sample pain, before pain is often radiated to left shoulder, left arm Inner side until little finger of toe with nameless, during panic attacks, can be with(Also can be without)Collapse, perspiration, short of breath, the worried, heart Throb with fear, the symptom such as nauseous or dizzy.
3rd, treatment method
From above-mentioned medicament, take to patient, each take 1 dose, early daily, evening respectively takes 1 time, is within 7 days a course for the treatment of, continuously takes With 3 courses for the treatment of.
4th, efficacy assessment standard
Effective:Coronary heart disease symptom disappears, and physique recovers normal, recovery from illness;
Take a turn for the better:Patient chest pain, uncomfortable in chest, short of breath, palpitaition, collapse, the symptom mitigation of perspiration, coronary heart disease symptom are substantially good Turn, physique is progressively recovered;
Invalid:Improvement standard person is not reached.
5th, treatment results(See the table below)
In above-mentioned treatment, with drug therapy patients with coronary heart disease of the present invention 31, as a result effective 25, obvious effective rate is 80.64%, Take a turn for the better 5, improvement rate is 16.12%, and invalid 1, total effective rate is 96.76%.

Claims (3)

1. a kind of medicine for treating coronary heart disease, it is characterised in that:It is made up of the bulk drug in following weight range:
15-25 gram of the red sage root, 10-20 gram of the fruit of Chinese magnoliavine, 5-15 gram of the tuber of dwarf lilyturf, 10-20 gram of polyporus lucidus, 10-20 gram of the root of herbaceous peony, root tuber of aromatic turmeric 5-15 Gram, 10-15 gram of hawthorn, 7-12 gram of radix pseudostellariae, 5-10 gram of Buddha's hand, 10-15 gram of honeysuckle, 10-15 gram of radix rehmanniae recen, caulis bambusae in taenian 5-15 Gram, 10-20 gram of ilex pubescens, 10-20 gram of paniculate swallowwort, 5-15 gram of Fructus Aurantii, 10-20 gram of barrenwort, 10-15 gram of radix polygonati officinalis, safflower 5-15 Gram, 10-20 gram of arillus longan, 7-12 gram of excrementum pteropi, polygala root 5-15 gram, 5-15 gram of the root of Dahurain angelica, 5-15 gram of myrrh, 5-15 gram of sophora flower are purple Perillaseed 10-20 gram, 5-15 gram of grass-leaved sweetflag, 10-20 gram of radix bupleuri, 5-15 gram of fushen, 10-20 gram of rush, 10-15 gram of radish seed, 5-15 gram of Japanese ardisia, 5-15 gram of cassia twig, 15-25 gram of Radix Angelicae Sinensis.
2. medicine according to claim 1, the consumption of wherein each bulk drug is:
20 grams of the red sage root, 15 grams of the fruit of Chinese magnoliavine, 10 grams of the tuber of dwarf lilyturf, 15 grams of polyporus lucidus, 15 grams of the root of herbaceous peony, 10 grams of root tuber of aromatic turmeric, 12 grams of hawthorn, radix pseudostellariae 9 grams, 8 grams of Buddha's hand, 12 grams of honeysuckle, 12 grams of radix rehmanniae recen, 10 grams of caulis bambusae in taenian, 15 grams of ilex pubescens, 15 grams of paniculate swallowwort, 10 grams of Fructus Aurantii are excessive 15 grams of the sheep leaves of pulse plants, 12 grams of radix polygonati officinalis, 10 grams of safflower, 15 grams of arillus longan, 9 grams of excrementum pteropi, 10 grams of polygala root, 10 grams of the root of Dahurain angelica, 10 grams of myrrh, Chinese scholartree 10 grams are spent, 15 grams of perilla seed, 10 grams of grass-leaved sweetflag, 15 grams of radix bupleuri, 10 grams of fushen, 15 grams of rush, 12 grams of radish seed, Japanese ardisia 10 Gram, 10 grams of cassia twig, 20 grams of Radix Angelicae Sinensis.
3. the preparation method of medicine according to claim 1 or claim 2, it comprises the following steps:
(One)Get the raw materials ready
(1)The red sage root:Net impurity is picked, rhizome is removed, is cleaned, is pulled out, cut into slices after running through, dry;
(2)The fruit of Chinese magnoliavine:Grey bits are weeded out, impurity is removed, is put in food steamer and is steamed thoroughly, taking-up is dried;
(3)The tuber of dwarf lilyturf:Net impurity is picked, is soaked in water, pulled out, after running through, pump the heart, then cleaned and dry;
(4)Polyporus lucidus:Impurity is removed, is cleaned, is softened, cut sheet, dried, weed out chip;
(5)The root of herbaceous peony:Impurity is picked, separates size, be soaked in water to eighty per cant thoroughly, pull out, solarization is dried in the air, moistened to inside and outside humidity uniformly, Section, dries;
(6)Root tuber of aromatic turmeric:It is soaked in water, cleans, pull solarization out and dry in the air, run through, cuts into slices, dry;
(7)Hawthorn:Net impurity is picked, core is weeded out;
(8)Radix pseudostellariae:Fibrous root is extractd, is dried;
(9)Buddha's hand:Impurity is picked, after being moistened with water spray, chopping is dried;
(10)Honeysuckle:Silt is weeded out, net impurity is picked;
(11)Radix rehmanniae recen:Crude drug is taken, impurity is removed, is cleaned, is slightly moistened, cut sheet, dried, weed out chip;
(12)Caulis bambusae in taenian:Hard bamboo let, impurity is removed, grey bits are shaked off, little group or segment is kneaded into;
(13)Ilex pubescens:Run through with water, segment is dried, weed out grey bits;
(14)Paniculate swallowwort:Net impurity is picked, is cleaned, is run through, be cut into 1.5 centimetres of sections, dry;
(15)Fructus Aurantii:Flesh, core being removed, being cleaned, is slightly soaked, pull out, soften, doubling being pinched with hand, section is dried;
(16)Barrenwort:Net impurity is picked, goes to obstruct, chopping weeds out chip;
(17)Radix polygonati officinalis:Impurity is removed, soil is cleaned, vexed profit is uniform to inside and outside humidity, section is dried;
(18)Safflower:Net impurity is picked, cauline leaf, base of a fruit head is removed, is dried;
(19)Arillus longan:Crude drug is taken, impurity is removed;
(20)Excrementum pteropi:Net impurity is picked, grey bits are smashed or weed out;
(21)Polygala root:Impurity is picked, segment weeds out grey bits;
(22)The root of Dahurain angelica:Pick net impurity, wash, soak, pull out and run through, slightly shine to crust without soapy feeling when, then after vexed profit, cut Piece is dried;
(23)Myrrh:Impurity is picked, fragment is broken into;
(24)Sophora flower:Crude drug is taken, stalk, leaf and impurity is removed, is weeded out grey bits;
(25)Perilla seed:Dedusting of winnowing with a dustpan is considered to be worth doing, is cleaned, is dried;
(26)Grass-leaved sweetflag:Impurity is picked, is cleaned, is slightly soaked, run through, cut into slices, dry;
(27)Radix bupleuri:Impurity is picked, residual stem is removed, silt is cleaned, is pulled out, cut into slices after running through in time, dried immediately;
(28)Fushen:Crude drug is taken, impurity is removed, is cleaned, is run through, be cut into foursquare or block, dry in the shade;
(29)Rush:Take rush to put in pot, the smaller pot of one bore of overlying, paste with blank sheet of paper, salt mudding is used in two pots of junctions Gu, do not make to lose heart, be calcined to blank sheet of paper and cease fire in coke yellow, take out after cooling completely;
(30)Radish seed:Winnow with a dustpan decontamination, rinse soil, pull out, dry, the used time smashs to pieces;
(31)Japanese ardisia:Impurity is removed, is cleaned, is slightly moistened, segment, dried;
(32)Cassia twig:Slightly soaked with water, pulled out, vexed moisten to saturating, section is dried, weeds out bits;
(33)Radix Angelicae Sinensis:Impurity is picked, is cleaned, vexed profit is slightly dried in the air, and section is dried;
(Two)Prepare
(1)The red sage root, the fruit of Chinese magnoliavine after by processing, the tuber of dwarf lilyturf, polyporus lucidus, the root of herbaceous peony, root tuber of aromatic turmeric, hawthorn, radix pseudostellariae, Buddha's hand, honeysuckle, life Glutinous rehmannia, caulis bambusae in taenian, ilex pubescens, paniculate swallowwort, Fructus Aurantii, barrenwort, radix polygonati officinalis, safflower, arillus longan, excrementum pteropi, polygala root, the root of Dahurain angelica, myrrh, Chinese scholartree Flower, perilla seed, grass-leaved sweetflag, radix bupleuri, fushen, rush, radish seed, Japanese ardisia, cassia twig, Radix Angelicae Sinensis are put in decocting container, add water 8 Measure again, after soaking 100 minutes, fry by intense fire to boil and rise, then with being cooked by slow fire 20 minutes, filter to obtain first time decoction liquor, by first Secondary decoction liquor is poured in container;
(2)The dregs of a decoction of filtration are added water 6 times and is measured, boiled by intense fire, then with being cooked by slow fire 20 minutes, filter to obtain second decoction liquor;
(3)Decoction liquor mixing and stirring twice is incited somebody to action, is divided into 4 doses and is taken.
CN201611129777.3A 2016-12-09 2016-12-09 A kind of treat medicine of coronary heart disease and preparation method thereof Withdrawn CN106492125A (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107375855A (en) * 2017-09-05 2017-11-24 王文春 One kind treats treating coronary heart disease and angina pectoris and preparation method thereof

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103432390A (en) * 2013-08-30 2013-12-11 董中影 Medicament for treating coronary heart disease and preparation method thereof
CN104547916A (en) * 2014-12-23 2015-04-29 赵明叶 Traditional Chinese medicine decoction for treating coronary heart disease

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103432390A (en) * 2013-08-30 2013-12-11 董中影 Medicament for treating coronary heart disease and preparation method thereof
CN104547916A (en) * 2014-12-23 2015-04-29 赵明叶 Traditional Chinese medicine decoction for treating coronary heart disease

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107375855A (en) * 2017-09-05 2017-11-24 王文春 One kind treats treating coronary heart disease and angina pectoris and preparation method thereof

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Application publication date: 20170315