CN106880690A - It is a kind of to treat medicine of hypogalactia after delivery and preparation method thereof - Google Patents

It is a kind of to treat medicine of hypogalactia after delivery and preparation method thereof Download PDF

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CN106880690A
CN106880690A CN201710284694.XA CN201710284694A CN106880690A CN 106880690 A CN106880690 A CN 106880690A CN 201710284694 A CN201710284694 A CN 201710284694A CN 106880690 A CN106880690 A CN 106880690A
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radix
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impurity
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徐士杰
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/481Astragalus (milkvetch)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/20Milk; Whey; Colostrum
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/232Angelica
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/233Bupleurum
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/236Ligusticum (licorice-root)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/25Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/284Atractylodes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/34Campanulaceae (Bellflower family)
    • A61K36/344Codonopsis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/34Campanulaceae (Bellflower family)
    • A61K36/346Platycodon
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/36Caryophyllaceae (Pink family), e.g. babysbreath or soapwort
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/65Paeoniaceae (Peony family), e.g. Chinese peony
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/71Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/75Rutaceae (Rue family)
    • A61K36/752Citrus, e.g. lime, orange or lemon
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/80Scrophulariaceae (Figwort family)
    • A61K36/804Rehmannia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/33Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/331Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/39Complex extraction schemes, e.g. fractionation or repeated extraction steps

Abstract

Medicine of hypogalactia after delivery and preparation method thereof is treated the invention discloses a kind of, it is mainly and is prepared from according to a certain weight ratio by the Radix Astragali, Radix Angelicae Sinensis, the root of Dahurain angelica, the seed of cowherb, Radix Rhapontici seu Radix Echinopsis, the stem pith of the rice-paper plant, the bighead atractylodes rhizome, dried orange peel, prepared rhizome of rehmannia, sheep breast, Ligusticum wallichii, radix bupleuri, rascal, there is medicine of the present invention promoting circulation of blood to stimulate the menstrual flow, expedite the emergence of lower breast, healing up sore and subduing swelling, clearing heat and detoxicating, the function of soothing the liver relieving stagnant Qi, for treating hypogalactia after delivery instant effect, good effect, do not recur.

Description

It is a kind of to treat medicine of hypogalactia after delivery and preparation method thereof
Technical field
Medicine of hypogalactia after delivery and preparation method thereof is treated the present invention relates to a kind of, belongs to the field of Chinese medicines.
Background technology
Hypogalactia after delivery refer to puerpera in lactation milk very less or completely without being insufficient to or even be unable to feeding infant.Hypogalactia Degree and situation are different:Lack during some beginning lactations, it is more slightly but still inadequate later;Have completely without milk, completely not Breast can be fed;After the normal lactation having, unexpected hyperpyrexia or seven feelings are crossed extremely, milk is suddenly few, is not enough to feeding infant.
Because western medicine side effect is big, therefore there is great need in people to the Chinese medicine of effectively treatment hypogalactia after delivery Ask, up to now, it has not been found that on relevant report of the invention.
The content of the invention
The present inventor have found effectively treatment postpartum finally according to the checking repeatedly of research and the clinical test of theory of traditional Chinese medical science The medicine of hypogalactia, so as to complete the present invention.
It is an object of the invention to provide a kind of Chinese medicine composition of effective treatment hypogalactia after delivery.
Another object of the present invention just there is provided the preparation method of the Chinese medicine composition.
Medicine of the present invention is the selection Radix Astragali, Radix Angelicae Sinensis, the root of Dahurain angelica, the seed of cowherb, Radix Rhapontici seu Radix Echinopsis, the stem pith of the rice-paper plant, the bighead atractylodes rhizome, dried orange peel, prepared rhizome of rehmannia, sheep Breast, Ligusticum wallichii, radix bupleuri, rascal, Radix Codonopsis, balloonflower root, the root of herbaceous peony, radix rehmanniae recen are combined preparation, and these drug regimens are caused into each medicine Thing effect produces synergy such that it is able to effectively treat hypogalactia after delivery.Wherein from the Radix Astragali because its nature and flavor is sweet, tepor, Enter lung, the spleen channel, life defends solid table with beneficial, and inducing diuresis for removing edema, eliminating toxic, the function of myogenic controls spontaneous perspiration, night sweat, blood-arthralgia, edema, ulcer Do not burst or burst and hold back long;Process with the function of having tonifying middle-Jiao and Qi, control internal injury overstrain, splenasthenic diarrhea, prolapse of the anus, deficiency of vital energy blood takes off, and collapses band and one Cut the disease of the laboured breathing deficiency of blood.From Radix Angelicae Sinensis because its nature and flavor sweet, acrid, warm, enters the heart, liver, the spleen channel, there is a benefiting blood and regulating blood circulation, menstruction regulating and pain relieving, The function of moisturize laxation, controls irregular menstruation, and Amenorrhea stomachache , Disorder lumps in the abdomen knot gathers, and uterine bleeding, headache due to deficiency of blood, dizziness, Impotence numbness, intestinal dryness is difficult just, Weight, ulcer sores, metal-inflicted wound, injury from falling down after dysentery characterized by blood in the stool.From the root of Dahurain angelica because its nature and flavor is pungent, temperature enters lung, spleen, stomach, dispels Wind, eliminating dampness, detumescence, the function of analgesic controls headache, pain in the supra-orbital bone, dentalgia, nasosinusitis, cold-dampness stomachache, intestines wind anal fistula, leukorrhea with reddish discharge, Ulcer sores, skin is dry itches, mange.From the seed of cowherb because its is bitter in taste flat, enter liver, stomach have promoting circulation of blood to stimulate the menstrual flow, and expedite the emergence of Lower breast, the function of healing up sore and subduing swelling controls women's Amenorrhea, alactation, difficult labour, blood strangury, carbuncle swells, metal-inflicted wound bleeding.From Radix Rhapontici seu Radix Echinopsis be because For its is bitter in taste salty-cold, enter stomach, large intestine channel, there is clearing heat and detoxicating, the function of lower breast controls the swollen pain of breast, alactation, heat toxin blood Dysentery, arthralgia.From the stem pith of the rice-paper plant because its property slightly sweet flavor, cool, enter lung, stomach, there is a purging the lung of pathogenic fire, diuresis, the function of lower milk, Control difficult urination, gonorrhoea, oedema, puerpera's alactation, blurred vision, nasal obstruction.From the bighead atractylodes rhizome because its nature and flavor bitter sweet, temperature, enter spleen, Stomach, there is a tonifying spleen, beneficial stomach, eliminating dampness, and in function, control deficient QI of the spleen and stomach, do not feel like eating, the few gas of burnout, empty swollen, diarrhea, phlegm and retained fluid, Oedema, jaundice, arthritis with fixed pain caused by dampness, difficult urination is dizzy, and spontaneous perspiration, nausea is uneasy.From dried orange peel because its is bitter in taste, pungent, temperature, return lung, The spleen channel, there is regulating qi-flowing for strengthening spleen, and eliminating dampness and eliminating phlegm function controls chest gastral cavity turgor, and deficiency of food is vomited and diarrhoea, coughing with a lot of sputum.From prepared rhizome of rehmannia because Its nature and flavor is sweet, and tepor enters liver and kidney channel, there is enriching yin, the function of enriching blood, and it is few to control deficiency of Yin blood, waist knee flaccidity, Cough osteopyrexia, seminal emission, Uterine bleeding, irregular menstruation is quenched one's thirst, number of urinating, deaf, blurred vision.From sheep breast because its nature and flavor is sweet, temperature has the function of gentle qi-restoratives, Control consumptive disease thin and weak, quench one's thirst, gastric disorder causing nausea, hiccup, aphtha, dermatitis rhus.From Ligusticum wallichii because its nature and flavor is pungent, temperature, enter liver, gallbladder channel have row Gas opens strongly fragrant, dispels pathogenic wind and remove dampness, the function of promoting blood circulation and stopping pain, controls air-cooled headache rotation and swoons, and hypochondriac pain abdomen pain, arthritis muscle contraction, Amenorrhea, difficult labour is produced Afterwards stasis blocking block bitterly, ulcer sores.It is cool from radix bupleuri because its is bitter in taste, enter liver, gallbladder channel, have with inducing diaphoresis, soothing the liver, rising Yang Function, control fevers and chills alternate, fullness in the chest and hypochondriac pain, bitter taste is deaf, headache and dizziness, malaria, lower sharp prolapse of the anus, irregular menstruation, metroptosis. From rascal because its nature and flavor toil, tepor, enter liver, gallbladder channel, there is soothing the liver relieving stagnant Qi, the function of dissipating bind dissolving phlegm controls chest side of body gastral cavilty Pain, hernia, dyspepsia, breast is swollen, newborn core, chronic malaria addiction block.From Radix Codonopsis because its nature and flavor is sweet, put down, start with, meridian of Foot-TAI YIN gas Point, there is tonifying middle-Jiao and Qi, the function of promoting the production of body fluid controls weakness of the spleen and the stomach, and qi-blood deficiency, body is tired powerless, and deficiency of food is thirsty, chronic diarrhea, prolapse of the anus.Choosing With balloonflower root because its nature and flavor toil, puts down, enter lung, stomach, there is out facilitaing lung gas, the function of eliminating the phlegm apocenosis controls exogenous cough, throat Swell and ache, lung carbuncle pyemesis, fullness in the chest and hypochondriac pain, dysentery stomachache.From the root of herbaceous peony because its nature and flavor picric acid, cool, enter liver, the spleen channel have blood-nourishing The cloudy function of receiving sweat is held back in soft liver, analgesic in delaying, and controls chest and abdomen pain over the hypochondriac region, diarrhea dysentery abdominal pain, spontaneous sweating, fever due to yin deficiency, and menstruation is not Adjust, uterine bleeding, under band.From radix rehmanniae recen because its nature and flavor is sweet, tremble with fear, the thoughts of returning home, liver and kidney channel have clearing heat and cooling blood, and yin-nourishing is promoted the production of body fluid Function, controls pyreticosis polydipsia, and yin asthenia generating intrinsic heat, hectic fever due to yin labor heat, Heat Diabetes is spitted blood, bleeding from five sense organs or subcutaneous tissue, spot dermexanthesis.
Specific embodiment
The drug dose of instant component is also that inventor summarizes what is drawn by largely groping, and the consumption of each component is following heavy All there is preferable curative effect in the range of amount:
15-25 grams of the Radix Astragali, 25-35 grams of Radix Angelicae Sinensis, 5-15 grams of the root of Dahurain angelica, 10-14 grams of the seed of cowherb, 10-15 grams of Radix Rhapontici seu Radix Echinopsis, stem pith of the rice-paper plant 5-10 Gram, 5-15 grams of the bighead atractylodes rhizome, 4-8 grams of dried orange peel, 10-20 grams of prepared rhizome of rehmannia, 25-35 grams of sheep breast, 4-8 grams of Ligusticum wallichii, 5-15 grams of radix bupleuri, rascal 4- 8 grams, 5-15 grams of Radix Codonopsis, 4-8 grams of balloonflower root, 4-8 grams of the root of herbaceous peony, 4-8 grams of radix rehmanniae recen.
Preferably:
20 grams of the Radix Astragali, 30 grams of Radix Angelicae Sinensis, 10 grams of the root of Dahurain angelica, 12 grams of the seed of cowherb, 12 grams of Radix Rhapontici seu Radix Echinopsis, 8 grams of the stem pith of the rice-paper plant, 10 grams of the bighead atractylodes rhizome, dried orange peel 6 Gram, 15 grams of prepared rhizome of rehmannia, 30 grams of sheep breast, 6 grams of Ligusticum wallichii, 10 grams of radix bupleuri, 6 grams of rascal, 10 grams of Radix Codonopsis, 6 grams of balloonflower root, 6 grams of the root of herbaceous peony, the dried rhizome of rehmannia It is yellow 6 grams.
The preparation method of medicine of the present invention is as follows
First, get the raw materials ready
1st, the Radix Astragali:Net impurity is picked, the root head and hollow larger root of residual is removed, is soaked in water, pulled out, cut in time after running through Piece, dries;
2nd, Radix Angelicae Sinensis:Impurity is picked, is cleaned, vexed profit is slightly dried in the air, and section is dried;
3rd, the root of Dahurain angelica:Pick net impurity, wash, soak, pull out and run through, slightly shine to crust without soapy feeling when, then after vexed profit, section Dry;
4th, the seed of cowherb:Winnow with a dustpan net impurity, put in pot, fried to popping with slow fire and taken out when spending six, seventy percent in vain, cool;
5th, Radix Rhapontici seu Radix Echinopsis:Net impurity is picked, unhairing is cleaned, run through, and is cut into slices, and is dried;
6th, the stem pith of the rice-paper plant:Impurity is picked, is cut into slices;
7th, the bighead atractylodes rhizome:Net impurity is picked, is soaked in water, pulled out after bubble, run through, cut into slices, dried;
8th, dried orange peel:Crude drug is taken, the pericarp of impurity and blackening is removed, wash quickly is net, softens, chopping, dries or low temperature drying, sieves Dedusting is considered to be worth doing;
9th, prepared rhizome of rehmannia:Select clean prepared rhizome of rehmannia;
10th, sheep breast:Take fresh sheep breast;
11st, Ligusticum wallichii:Impurity is picked, large and small is separated, is soaked in water, solarization is dried in the air, cut into slices after vexed profit, dried;
12nd, radix bupleuri:Impurity is picked, residual stem is removed, silt is cleaned, pulled out, section in time, dries immediately after running through;
13rd, rascal:Net impurity is picked, is soaked in water, pulled out, run through, cut into slices, dried;
14th, Radix Codonopsis:Reed, section or segment are run through after cleaning silt, is dried;
15th, balloonflower root:Net impurity is picked, except removing LU, is cleaned and is pulled out, cut into slices after running through, dried;
16th, the root of herbaceous peony:Impurity is picked, size is separated, is soaked in water to eighty per cant thoroughly, pulled out, solarization is dried in the air, profit is uniform to inside and outside humidity, Section, dries;
17th, radix rehmanniae recen:Crude drug is taken, impurity is removed, cleaned, slightly moistened, cut sheet, dried, weed out chip.
2nd, prepare
1st, by the Radix Astragali of the weight, Radix Angelicae Sinensis, the root of Dahurain angelica, the seed of cowherb, Radix Rhapontici seu Radix Echinopsis, the stem pith of the rice-paper plant, the bighead atractylodes rhizome, dried orange peel, prepared rhizome of rehmannia, Ligusticum wallichii, bavin Recklessly, rascal, Radix Codonopsis, balloonflower root, the root of herbaceous peony, radix rehmanniae recen are put into decocting container, are added water 6 times and are measured, and after soaking 100 minutes, intense fire is decocted Boiling, then with being cooked by slow fire 20 minutes, first time decoction liquor is filtered to obtain, first time decoction liquor is poured into container;
2nd, the dregs of a decoction of filtering are added water 4 times and is measured, boiled by intense fire, then with being cooked by slow fire 20 minutes, filter to obtain second decoction liquor;
3rd, separately sheep breast is boiled;
4th, add sheep breast to stir decoction liquor mixing twice, be divided into 2 doses and take.
The seed of cowherb has promoting circulation of blood to stimulate the menstrual flow in prescription, expedites the emergence of lower breast, and the function of healing up sore and subduing swelling is monarch drug in a prescription;Radix Rhapontici seu Radix Echinopsis has heat-clearing solution Poison, the function of lower breast;The stem pith of the rice-paper plant has a diuresis, the function of lower milk, and the two is ministerial drug, and three taste medicines play promoting circulation of blood and stimulate the menstrual flow, urge jointly Breast is given birth to, healing up sore and subduing swelling, clearing heat and detoxicating effect, treatment hypogalactia after delivery effect comprehensively, and is stimulated the menstrual flow with promoting circulation of blood, expedites the emergence of lower breast, clearly Can be effected a permanent cure based on thermal detoxification, rascal has soothing the liver relieving stagnant Qi, and the function of dissipating bind dissolving phlegm is adjutant, and radix rehmanniae recen has clearing heat and cooling blood, and yin-nourishing is raw To make medicine, all medicines are to take stopgap measures to the function in Tianjin with being left.
There is medicine of the present invention promoting circulation of blood to stimulate the menstrual flow, and expedite the emergence of lower breast, and healing up sore and subduing swelling is clearing heat and detoxicating, and the function of soothing the liver relieving stagnant Qi is used for Treatment hypogalactia after delivery, short treating period, instant effect, non-relapse after healing.
The beneficial effect of medicine of the present invention is expanded on further below by way of test example, these test examples include this hair The animal toxicity test report of bright medicine and clinical observation on the therapeutic effect data.
The animal toxicity test report of [test example 1] medicine of the present invention:
Rabbit 30 is taken, male and female dual-purpose, 2.0-2.5kg of body weight is divided to two groups, and every group 15, one of which is tested for overdose Group, another group is normal amount test group.Super quantity group is 20ml/kg, and normal amount is 10ml/kg, and administering mode is given for administration by gavage Medicine, twice daily, takes medicine continuously 7 days, the reaction of observation administration daily, as a result shows that two groups of rabbit activities, diet are normal, and medicine is without bad Toxic and side effect.
The clinical observation on the therapeutic effect of [test example 2] medicine of the present invention
1st, physical data
Accept hypogalactia after delivery out-patient totally 42 for medical treatment.
2nd, diagnostic criteria
Classical symptom be in 2-3 days postpartum to two weeks milk very less or completely without being insufficient to or even be unable to feeding infant.
3rd, treatment method
From above-mentioned medicament, taken to patient, each take 1 dose, early daily, evening respectively takes 1 time, be within 7 days a course for the treatment of, continuous clothes With 2 courses for the treatment of.
4th, efficacy assessment standard
It is effective:Hypogalactia after delivery symptom disappears, and recovers normal, recovery from illness;
Take a turn for the better:Hypogalactia after delivery symptom is clearly better, and progressively recovers normal;
It is invalid:Improvement standard person is not reached.
5th, treatment results(See the table below)
In above-mentioned treatment, with drug therapy hypogalactia after delivery patient 42 of the present invention, as a result effective 35, obvious effective rate is 83.3%, Take a turn for the better 5, improvement rate is 11.9%, and invalid 2, total effective rate is 95.2%.

Claims (3)

1. a kind of medicine for treating hypogalactia after delivery, it is characterised in that:It is made up of the bulk drug in following weight range:
15-25 grams of the Radix Astragali, 25-35 grams of Radix Angelicae Sinensis, 5-15 grams of the root of Dahurain angelica, 10-14 grams of the seed of cowherb, 10-15 grams of Radix Rhapontici seu Radix Echinopsis, stem pith of the rice-paper plant 5-10 Gram, 5-15 grams of the bighead atractylodes rhizome, 4-8 grams of dried orange peel, 10-20 grams of prepared rhizome of rehmannia, 25-35 grams of sheep breast, 4-8 grams of Ligusticum wallichii, 5-15 grams of radix bupleuri, rascal 4- 8 grams, 5-15 grams of Radix Codonopsis, 4-8 grams of balloonflower root, 4-8 grams of the root of herbaceous peony, 4-8 grams of radix rehmanniae recen.
2. medicine according to claim 1, wherein the consumption of each bulk drug is:
20 grams of the Radix Astragali, 30 grams of Radix Angelicae Sinensis, 10 grams of the root of Dahurain angelica, 12 grams of the seed of cowherb, 12 grams of Radix Rhapontici seu Radix Echinopsis, 8 grams of the stem pith of the rice-paper plant, 10 grams of the bighead atractylodes rhizome, dried orange peel 6 Gram, 15 grams of prepared rhizome of rehmannia, 30 grams of sheep breast, 6 grams of Ligusticum wallichii, 10 grams of radix bupleuri, 6 grams of rascal, 10 grams of Radix Codonopsis, 6 grams of balloonflower root, 6 grams of the root of herbaceous peony, the dried rhizome of rehmannia It is yellow 6 grams.
3. the preparation method of medicine according to claim 1 or claim 2, it comprises the following steps:
(One)Get the raw materials ready
(1)The Radix Astragali:Net impurity is picked, the root head and hollow larger root of residual is removed, is soaked in water, pulled out, cut in time after running through Piece, dries;
(2)Radix Angelicae Sinensis:Impurity is picked, is cleaned, vexed profit is slightly dried in the air, and section is dried;
(3)The root of Dahurain angelica:Pick net impurity, wash, soak, pull out and run through, slightly shine to crust without soapy feeling when, then after vexed profit, cut Piece is dried;
(4)The seed of cowherb:Winnow with a dustpan net impurity, put in pot, fried to popping with slow fire and taken out when spending six, seventy percent in vain, cool;
(5)Radix Rhapontici seu Radix Echinopsis:Net impurity is picked, unhairing is cleaned, run through, and is cut into slices, and is dried;
(6)The stem pith of the rice-paper plant:Impurity is picked, is cut into slices;
(7)The bighead atractylodes rhizome:Net impurity is picked, is soaked in water, pulled out after bubble, run through, cut into slices, dried;
(8)Dried orange peel:Crude drug is taken, the pericarp of impurity and blackening is removed, wash quickly is net, softens, chopping, dries or low temperature drying, Weed out grey bits;
(9)Prepared rhizome of rehmannia:Select clean prepared rhizome of rehmannia;
(10)Sheep breast:Take fresh sheep breast;
(11)Ligusticum wallichii:Impurity is picked, large and small is separated, is soaked in water, solarization is dried in the air, cut into slices after vexed profit, dried;
(12)Radix bupleuri:Impurity is picked, residual stem is removed, silt is cleaned, pulled out, section in time, dries immediately after running through;
(13)Rascal:Net impurity is picked, is soaked in water, pulled out, run through, cut into slices, dried;
(14)Radix Codonopsis:Reed, section or segment are run through after cleaning silt, is dried;
(15)Balloonflower root:Net impurity is picked, except removing LU, is cleaned and is pulled out, cut into slices after running through, dried;
(16)The root of herbaceous peony:Impurity is picked, size is separated, is soaked in water to eighty per cant thoroughly, pulled out, solarization is dried in the air, profit is uniform to inside and outside humidity, Section, dries;
(17)Radix rehmanniae recen:Crude drug is taken, impurity is removed, cleaned, slightly moistened, cut sheet, dried, weed out chip;
(Two)Prepare
(1)By the Radix Astragali of the weight, Radix Angelicae Sinensis, the root of Dahurain angelica, the seed of cowherb, Radix Rhapontici seu Radix Echinopsis, the stem pith of the rice-paper plant, the bighead atractylodes rhizome, dried orange peel, prepared rhizome of rehmannia, Ligusticum wallichii, bavin Recklessly, rascal, Radix Codonopsis, balloonflower root, the root of herbaceous peony, radix rehmanniae recen are put into decocting container, are added water 6 times and are measured, and after soaking 100 minutes, intense fire is decocted Boiling, then with being cooked by slow fire 20 minutes, first time decoction liquor is filtered to obtain, first time decoction liquor is poured into container;
(2)The dregs of a decoction of filtering are added water 4 times and is measured, boiled by intense fire, then with being cooked by slow fire 20 minutes, filter to obtain second decoction liquor;
(3)Separately sheep breast is boiled;
(4)Add sheep breast to stir decoction liquor mixing twice, be divided into 2 doses and take.
CN201710284694.XA 2017-04-27 2017-04-27 It is a kind of to treat medicine of hypogalactia after delivery and preparation method thereof Pending CN106880690A (en)

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Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
何清湖等: "《中西医临床用药手册 妇科分册》", 31 March 2010, 湖南科学技术出版社 *
刘胜春等: "通乳络方治疗产后缺乳90例观察", 《中成药》 *

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