CN115968888B - Preparation for preventing and controlling grassland mouse damage and application thereof - Google Patents
Preparation for preventing and controlling grassland mouse damage and application thereof Download PDFInfo
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- CN115968888B CN115968888B CN202310106059.8A CN202310106059A CN115968888B CN 115968888 B CN115968888 B CN 115968888B CN 202310106059 A CN202310106059 A CN 202310106059A CN 115968888 B CN115968888 B CN 115968888B
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- 238000002360 preparation method Methods 0.000 title claims abstract description 10
- TZCXTZWJZNENPQ-UHFFFAOYSA-L barium sulfate Chemical compound [Ba+2].[O-]S([O-])(=O)=O TZCXTZWJZNENPQ-UHFFFAOYSA-L 0.000 claims abstract description 27
- 241000700159 Rattus Species 0.000 claims abstract description 19
- MUBZPKHOEPUJKR-UHFFFAOYSA-N Oxalic acid Chemical compound OC(=O)C(O)=O MUBZPKHOEPUJKR-UHFFFAOYSA-N 0.000 claims abstract description 18
- HYPPXZBJBPSRLK-UHFFFAOYSA-N diphenoxylate Chemical compound C1CC(C(=O)OCC)(C=2C=CC=CC=2)CCN1CCC(C#N)(C=1C=CC=CC=1)C1=CC=CC=C1 HYPPXZBJBPSRLK-UHFFFAOYSA-N 0.000 claims abstract description 7
- 229960004192 diphenoxylate Drugs 0.000 claims abstract description 7
- 235000006408 oxalic acid Nutrition 0.000 claims abstract description 6
- 241000699670 Mus sp. Species 0.000 claims description 14
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 claims description 12
- 240000008790 Musa x paradisiaca Species 0.000 claims description 8
- 235000018290 Musa x paradisiaca Nutrition 0.000 claims description 8
- WHUUTDBJXJRKMK-UHFFFAOYSA-N Glutamic acid Natural products OC(=O)C(N)CCC(O)=O WHUUTDBJXJRKMK-UHFFFAOYSA-N 0.000 claims description 7
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- ROHFNLRQFUQHCH-UHFFFAOYSA-N Leucine Natural products CC(C)CC(N)C(O)=O ROHFNLRQFUQHCH-UHFFFAOYSA-N 0.000 claims description 7
- 235000013922 glutamic acid Nutrition 0.000 claims description 7
- 239000004220 glutamic acid Substances 0.000 claims description 7
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 claims description 6
- 239000008103 glucose Substances 0.000 claims description 6
- 239000011780 sodium chloride Substances 0.000 claims description 6
- 241000699666 Mus <mouse, genus> Species 0.000 claims description 5
- 239000002285 corn oil Substances 0.000 claims description 5
- 235000005687 corn oil Nutrition 0.000 claims description 5
- 241000699694 Gerbillinae Species 0.000 claims description 4
- 235000021307 Triticum Nutrition 0.000 claims description 2
- 238000009472 formulation Methods 0.000 claims description 2
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- 150000001413 amino acids Chemical class 0.000 abstract description 5
- 235000019629 palatability Nutrition 0.000 abstract description 5
- 150000003839 salts Chemical class 0.000 abstract description 4
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- 230000001276 controlling effect Effects 0.000 abstract 3
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- 208000014674 injury Diseases 0.000 abstract 2
- 238000012360 testing method Methods 0.000 description 14
- 230000000694 effects Effects 0.000 description 9
- 239000003795 chemical substances by application Substances 0.000 description 7
- 238000000034 method Methods 0.000 description 6
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- WHUUTDBJXJRKMK-VKHMYHEASA-N L-glutamic acid Chemical compound OC(=O)[C@@H](N)CCC(O)=O WHUUTDBJXJRKMK-VKHMYHEASA-N 0.000 description 3
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Classifications
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
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- Agricultural Chemicals And Associated Chemicals (AREA)
Abstract
The invention provides a preparation for preventing and controlling the damage of grassland rats, which comprises the following components, by weight, 0.005% -0.5% of diphenoxylate, 10% -30% of barium sulfate, 1-30% of an attractant and 100% of grains; the attractant consists of 1-10% of vegetable oil, 0.5-5% of plant essence, 0.5-3% of amino acid, 0.5-5% of oxalic acid, 1-8% of salt and 1-25% of sugar. The preparation for preventing and controlling the grassland mouse injury, which is prepared by the invention, has excellent palatability and can improve the preventing and controlling effect on the grassland mouse injury.
Description
Technical Field
The invention relates to the technical field of rodenticides, in particular to a preparation for preventing and controlling the damage of grassland rats and application thereof.
Background
The grassland resources in China are rich, and the grassland resources are paid more attention all the time. However, due to overgrazing and overreclamation, the grassland desertification phenomenon is serious, and the grassland degradation phenomenon is serious. In such cases, the rat hazard is provided with a warm bed, making it more rampant. Grassland rats belong to the group of living rats, can dig holes continuously, and have stronger gnawing capability. Through continuous gnawing, underground root systems can be damaged greatly, so that healthy growth of pasture is affected. In addition, grassland mice have a strong ability to reproduce themselves and no hibernation period. Under the condition that the environment is suitable for the growth of mice, the propagation speed can be gradually increased, and the mice can become disasters after mass propagation, so that the damage to grasslands is caused to different degrees. If the control strength is insufficient, the damage of the mice cannot be effectively eliminated, malignant circulation can be generated, and the ecological environment of the grassland is continuously destroyed. Therefore, the prevention and control of the rat damage are required to be emphasized, and the prevention and control force is continuously improved.
The most outstanding advantage is that the chemical prevention and treatment measures can take effect in a short time, and the application range is relatively wide. The 20.02% diphenoxylate-barium sulfate bait for PD20102144 registered by Liaoning micro engineering Co-Ltd is a low-toxicity rodenticide, which is prepared by mixing diphenoxylate and barium sulfate, has the action mechanism of promoting intestinal obstruction of mice to cause the death of the mice, and has a good effect on preventing and controlling the mice. However, the control effect of 20.02% of the diphenhydrate barium sulfate bait in the control of grassland rats is reduced to different degrees, the reason is probably that the attractant in the chemical control of rats directly affects the preference degree of rats to a certain rodenticide, but the use of olfactory attractants must be paid attention to the good palatability of the bait used, so that the consumption can be increased after the rats are introduced by the attractants. Under certain conditions, however, the olfactory attractant may be converted to a strong antifeedant signal. The composite baits are mostly used abroad, namely, a plurality of raw materials are simultaneously used, the baits used in China are mixed according to a certain proportion, so that the baits are single, and the baits are probably unsuitable for a small number of individuals. Meanwhile, as the same kind of baits are repeatedly used, especially for short-term internal connection, the feeding refusal is enhanced, the killing effect is rapidly reduced, and the chemical control effect is seriously affected. Therefore, the screening of the attractant becomes a key to the development of rodenticides.
Disclosure of Invention
The invention aims to provide a preparation for preventing and treating grassland rats, which has excellent palatability and better prevention and treatment, and the specific technical scheme is as follows:
the preparation for preventing and controlling the grassland mouse damage is characterized by comprising the following components, by weight, 0.005% -0.5% of diphenoxylate, 10% -30% of barium sulfate, 1-30% of an attractant and 100% of grains;
in the invention, the attractant consists of 1-10 parts by weight of vegetable oil, 0.5-5 parts by weight of plant essence, 0.5-3 parts by weight of amino acid, 0.5-5 parts by weight of oxalic acid, 1-8 parts by weight of salt and 1-25 parts by weight of sugar.
In the invention, the vegetable oil is one or more of corn oil, peanut oil, rapeseed oil or sunflower oil; the plant essence is one or more of banana essence and pineapple essence; the amino acid is one or more of tryptophan, glutamic acid, leucine or serine; the salt is sodium chloride; the sugar is one or more of glucose and fructose; the grain is one or more of wheat, corn or rice.
In the invention, the vegetable oil is corn oil; the plant essence is one or more of banana essence and pineapple essence; the amino acid is one or more of glutamic acid and leucine; the salt is sodium chloride; the sugar is glucose.
The plant essence is a combination of banana essence and pineapple essence, and the mass ratio of the banana essence to the pineapple essence is 1:5-5:1; the amino acid is a combination of glutamic acid and leucine; the mass ratio of the two is 1:10-10:1.
The invention provides an application of a preparation for preventing and treating the damage of grassland rats in preventing and treating the damage of the grassland rats. The preparation method comprises the steps of the following steps of a, a british vole, a long-claw gerbil and a grassland yellow vole.
By adopting the technical scheme, the invention has the following beneficial effects:
Compared with the known 20.02% of the diphenhydrate barium sulfate bait, the bait prepared by selecting a proper attractant has excellent palatability.
The rodenticide prepared by the invention has a better rodenticide effect than a control medicament T7 at the same dosage, and the application amount of the medicament can reach over 80 percent of control effect at 1.0kg/hm < 2 >.
Detailed Description
The invention is further illustrated with reference to specific embodiments.
Example 1: test report of field efficacy of bait for preventing and controlling grassland mice
1. Purpose of test
Screening the attractant capable of improving palatability to prepare bait and verifying the technical effect.
2. Test conditions
2.1 Selection of test subjects, crops and varieties
Buchner, gerbil, grassland yellow mouse
Inner Mongolia typical grassland area (inner Mongolia autonomous area tin Lin Guole allies Abagaflag)
2.1 Environmental conditions
The test area is not irrigated manually and mainly depends on natural rainfall. The test area is formed as a flat land and a gentle slope. The main vegetation in the test area is herba Caprae Seu Ovis, rhizoma Imperatae, herba Alii Fistulosi, and herba Alii Fistulosi. The main species of the mice are Buchner rats, gerbils, grassland yellow rats and the like, and the main species of the mice are pasture grass competing with livestock, plant vegetation damaging by digging holes and the like. Natural enemies mainly comprise Ai You, hawk, falcon and the like.
3. Test design and arrangement
3.1 Test Agents
TABLE 1 formulation design of pharmaceutical agents
Control agent 7:20.02% of a delphinium barium sulfate bait (PD 20102144 registered by Liaoning micro engineering Co., ltd.).
3.2 Dosage and numbering of the medicament
TABLE 2 test design of reagents for test
3.3 Cell area and repetition
Cell area: 5 hectares/min
Number of repetitions: 0
3.4 Method of administering the drug
The using method comprises the following steps: in sunny days, the bait is evenly spread on the sample plot, and 1 time of sufficient bait is fed.
Applicator instrument: plastic cup
Time and frequency of application: spreading for 1 time in the middle 4 months of spring
4. Investigation, recording and measuring method
4.1 Investigation method
Murine density investigation: according to national standard (GB/T17980.68-2004), the density of mice was investigated by the plug hole for robbing method. All rat holes of the control and treatment cells were plugged before treatment and the number of stolen rat holes was investigated after 24h, expressed as effective holes/hm 2 as rat density.
Investigation of bait feeding conditions: 20 bait stations were placed in each plot and used as receptacles. After 150g of the bait was put in, continuous observation was performed for 3d. The bait consumption per day was recorded.
4.2 Method for calculating efficacy
4.3 Direct impact on crop plants (not found), impact on other non-target organisms (not found)
5. Results and analysis
From the statistical analysis in Table 3, it was shown that the bait consumption of the T1-T6 test agent was higher than that of the control agent T7 on days 2 and 3, and that the consumption elevation rates were 44.1%, 22.0%, 19.8%, 9.6%, 4.5%, 6.6% by the T1-T6 compared to the T7 agent treatment on days 3, respectively.
TABLE 3 statistical table of test results of feeding coefficient of grassland raticide to bait
The statistical analysis of the table 3 shows that the deratization effect of the T1-T6 bait with the same dosage is obviously better than that of the control agent T7, and the control effect of more than 80 percent can be achieved when the application amount of the agent is 1.0kg/hm 2.
Table 4 statistical table of test results of bait for controlling grassland mice
Example 2
20.05% Of diphenhydrate barium sulfate bait
Diphenoxylate 0.05%, barium sulfate 20%, corn oil 5%, banana essence 0.4%, pineapple essence 0.6%, glutamic acid 0.2%, leucine 0.8%, oxalic acid 1.5%, sodium chloride 5%, glucose 20% and grain 100%.
30.1% Of diphenhydrate barium sulfate bait
0.1% Of diphenoxylate, 30% of barium sulfate, 3% of corn oil, 0.8% of banana essence, 0.5% of glutamic acid, 0.5% of leucine, 3% of oxalic acid, 4% of sodium chloride, 18% of glucose and 100% of grain.
25.2% Diphenhydrate barium sulfate bait
0.2% Of diphenoxylate, 25% of barium sulfate, 3% of peanut oil, 1.5% of banana essence, 0.8% of glutamic acid, 0.7% of leucine, 2% of oxalic acid, 4% of sodium chloride, 20% of glucose and 100% of grain.
Finally, it should be noted that: the above embodiments are only for illustrating the technical solution of the present invention, and not for limiting the same.
Claims (2)
1. A preparation for preventing and controlling the damage of grassland rats is characterized by comprising the following components in percentage by weight, 0.02% of diphenoxylate, 20% of barium sulfate, 8% of corn oil, 3% of banana essence, 0.5% of glutamic acid, 0.5% of leucine, 2% of oxalic acid, 4% of sodium chloride, 15% of glucose and 100% of wheat flour.
2. Use of the formulation according to claim 1 for controlling grassland mouse pests, characterized in that the grassland mouse pests are brifield mice, gerbil, grassland yellow mice.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
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CN202310106059.8A CN115968888B (en) | 2023-02-13 | 2023-02-13 | Preparation for preventing and controlling grassland mouse damage and application thereof |
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CN202310106059.8A CN115968888B (en) | 2023-02-13 | 2023-02-13 | Preparation for preventing and controlling grassland mouse damage and application thereof |
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CN115968888A CN115968888A (en) | 2023-04-18 |
CN115968888B true CN115968888B (en) | 2024-05-31 |
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CN202310106059.8A Active CN115968888B (en) | 2023-02-13 | 2023-02-13 | Preparation for preventing and controlling grassland mouse damage and application thereof |
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Citations (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1118652A (en) * | 1994-05-10 | 1996-03-20 | 浙江省粮食科学研究所 | Safety mouse killing bait |
CN1242934A (en) * | 1998-07-29 | 2000-02-02 | 周良勇 | Toxinless chemical for rat eradication |
CN1352879A (en) * | 2001-11-27 | 2002-06-12 | 朱天相 | Biochemical rodenticide |
JP2003212701A (en) * | 2002-01-16 | 2003-07-30 | Earth Chem Corp Ltd | Poison bait for rat and method for stabilizing the same |
JP2003292404A (en) * | 2002-02-04 | 2003-10-15 | Earth Chem Corp Ltd | Poisonous feed agent against rat and method for stabilizing the same |
CN102187883A (en) * | 2010-12-08 | 2011-09-21 | 单承仪 | Nontoxic type high expansion solidification lethal rodent bait and preparation method thereof |
CN112806366A (en) * | 2021-01-11 | 2021-05-18 | 四川益万家环境工程有限公司 | Efficient, environment-friendly and nontoxic rat killing medicine |
CN115005235A (en) * | 2022-06-28 | 2022-09-06 | 辽宁微科生物工程有限公司 | Microbial rodenticide |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB2410436A (en) * | 2004-01-30 | 2005-08-03 | Reckitt Benckiser | Rodenticidal bait composition |
-
2023
- 2023-02-13 CN CN202310106059.8A patent/CN115968888B/en active Active
Patent Citations (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1118652A (en) * | 1994-05-10 | 1996-03-20 | 浙江省粮食科学研究所 | Safety mouse killing bait |
CN1242934A (en) * | 1998-07-29 | 2000-02-02 | 周良勇 | Toxinless chemical for rat eradication |
CN1352879A (en) * | 2001-11-27 | 2002-06-12 | 朱天相 | Biochemical rodenticide |
JP2003212701A (en) * | 2002-01-16 | 2003-07-30 | Earth Chem Corp Ltd | Poison bait for rat and method for stabilizing the same |
JP2003292404A (en) * | 2002-02-04 | 2003-10-15 | Earth Chem Corp Ltd | Poisonous feed agent against rat and method for stabilizing the same |
CN102187883A (en) * | 2010-12-08 | 2011-09-21 | 单承仪 | Nontoxic type high expansion solidification lethal rodent bait and preparation method thereof |
CN112806366A (en) * | 2021-01-11 | 2021-05-18 | 四川益万家环境工程有限公司 | Efficient, environment-friendly and nontoxic rat killing medicine |
CN115005235A (en) * | 2022-06-28 | 2022-09-06 | 辽宁微科生物工程有限公司 | Microbial rodenticide |
Non-Patent Citations (1)
Title |
---|
韩崇选 等.安全型无公害灭鼠剂—克鼠星的研究.2002,第17卷(第3期),第44-47页. * |
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