CN115968888A - Preparation for preventing and treating grassland mouse injury and application thereof - Google Patents
Preparation for preventing and treating grassland mouse injury and application thereof Download PDFInfo
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- CN115968888A CN115968888A CN202310106059.8A CN202310106059A CN115968888A CN 115968888 A CN115968888 A CN 115968888A CN 202310106059 A CN202310106059 A CN 202310106059A CN 115968888 A CN115968888 A CN 115968888A
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- 230000006378 damage Effects 0.000 title claims abstract description 14
- 208000027418 Wounds and injury Diseases 0.000 title claims abstract description 8
- 208000014674 injury Diseases 0.000 title claims abstract description 8
- TZCXTZWJZNENPQ-UHFFFAOYSA-L barium sulfate Chemical compound [Ba+2].[O-]S([O-])(=O)=O TZCXTZWJZNENPQ-UHFFFAOYSA-L 0.000 claims abstract description 23
- MUBZPKHOEPUJKR-UHFFFAOYSA-N Oxalic acid Chemical compound OC(=O)C(O)=O MUBZPKHOEPUJKR-UHFFFAOYSA-N 0.000 claims abstract description 18
- 239000005667 attractant Substances 0.000 claims abstract description 13
- 230000031902 chemoattractant activity Effects 0.000 claims abstract description 12
- 241000607479 Yersinia pestis Species 0.000 claims abstract description 11
- 241000283984 Rodentia Species 0.000 claims abstract description 9
- 150000001413 amino acids Chemical class 0.000 claims abstract description 9
- HYPPXZBJBPSRLK-UHFFFAOYSA-N diphenoxylate Chemical compound C1CC(C(=O)OCC)(C=2C=CC=CC=2)CCN1CCC(C#N)(C=1C=CC=CC=1)C1=CC=CC=C1 HYPPXZBJBPSRLK-UHFFFAOYSA-N 0.000 claims abstract description 7
- 229960004192 diphenoxylate Drugs 0.000 claims abstract description 7
- 150000003839 salts Chemical class 0.000 claims abstract description 7
- 235000015112 vegetable and seed oil Nutrition 0.000 claims abstract description 7
- 239000008158 vegetable oil Substances 0.000 claims abstract description 7
- 235000006408 oxalic acid Nutrition 0.000 claims abstract description 6
- 150000001720 carbohydrates Chemical class 0.000 claims abstract description 3
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical group [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 claims description 14
- WHUUTDBJXJRKMK-UHFFFAOYSA-N Glutamic acid Natural products OC(=O)C(N)CCC(O)=O WHUUTDBJXJRKMK-UHFFFAOYSA-N 0.000 claims description 9
- ROHFNLRQFUQHCH-YFKPBYRVSA-N L-leucine Chemical compound CC(C)C[C@H](N)C(O)=O ROHFNLRQFUQHCH-YFKPBYRVSA-N 0.000 claims description 9
- ROHFNLRQFUQHCH-UHFFFAOYSA-N Leucine Natural products CC(C)CC(N)C(O)=O ROHFNLRQFUQHCH-UHFFFAOYSA-N 0.000 claims description 9
- 240000008790 Musa x paradisiaca Species 0.000 claims description 9
- 235000018290 Musa x paradisiaca Nutrition 0.000 claims description 9
- 235000013922 glutamic acid Nutrition 0.000 claims description 9
- 239000004220 glutamic acid Substances 0.000 claims description 9
- 235000001014 amino acid Nutrition 0.000 claims description 8
- 244000099147 Ananas comosus Species 0.000 claims description 7
- 235000007119 Ananas comosus Nutrition 0.000 claims description 7
- 241000196324 Embryophyta Species 0.000 claims description 7
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 claims description 7
- 235000013339 cereals Nutrition 0.000 claims description 7
- 239000008103 glucose Substances 0.000 claims description 7
- 239000011780 sodium chloride Substances 0.000 claims description 7
- WHUUTDBJXJRKMK-VKHMYHEASA-N L-glutamic acid Chemical compound OC(=O)[C@@H](N)CCC(O)=O WHUUTDBJXJRKMK-VKHMYHEASA-N 0.000 claims description 6
- 239000002285 corn oil Substances 0.000 claims description 6
- 235000005687 corn oil Nutrition 0.000 claims description 6
- 235000019483 Peanut oil Nutrition 0.000 claims description 3
- 239000000312 peanut oil Substances 0.000 claims description 3
- MTCFGRXMJLQNBG-REOHCLBHSA-N (2S)-2-Amino-3-hydroxypropansäure Chemical compound OC[C@H](N)C(O)=O MTCFGRXMJLQNBG-REOHCLBHSA-N 0.000 claims description 2
- 241000699800 Cricetinae Species 0.000 claims description 2
- 229930091371 Fructose Natural products 0.000 claims description 2
- RFSUNEUAIZKAJO-ARQDHWQXSA-N Fructose Chemical compound OC[C@H]1O[C@](O)(CO)[C@@H](O)[C@@H]1O RFSUNEUAIZKAJO-ARQDHWQXSA-N 0.000 claims description 2
- 239000005715 Fructose Substances 0.000 claims description 2
- QIVBCDIJIAJPQS-VIFPVBQESA-N L-tryptophane Chemical compound C1=CC=C2C(C[C@H](N)C(O)=O)=CNC2=C1 QIVBCDIJIAJPQS-VIFPVBQESA-N 0.000 claims description 2
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- QIVBCDIJIAJPQS-UHFFFAOYSA-N Tryptophan Natural products C1=CC=C2C(CC(N)C(O)=O)=CNC2=C1 QIVBCDIJIAJPQS-UHFFFAOYSA-N 0.000 claims description 2
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- 125000002791 glucosyl group Chemical group C1([C@H](O)[C@@H](O)[C@H](O)[C@H](O1)CO)* 0.000 claims description 2
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- 241000700114 Chinchillidae Species 0.000 claims 1
- 230000000694 effects Effects 0.000 abstract description 11
- 235000019629 palatability Nutrition 0.000 abstract description 5
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- 241000700159 Rattus Species 0.000 description 16
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Classifications
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Agricultural Chemicals And Associated Chemicals (AREA)
Abstract
The invention provides a preparation for preventing and treating rodent pests in grassland, which comprises the following components in percentage by weight, diphenoxylate 0.005-0.5%, barium sulfate 10-30%, attractant 1-30%, and grain complement to 100%; the attractant consists of 1-10% of vegetable oil, 0.5-5% of plant essence, 0.5-3% of amino acid, 0.5-5% of oxalic acid, 1-8% of salt and 1-25% of saccharide. The preparation for preventing and treating the grassland mouse injury prepared by the invention has excellent palatability and can improve the prevention and treatment effect on the grassland mouse injury.
Description
Technical Field
The invention relates to the technical field of rodenticides, in particular to a preparation for preventing and treating grassland mouse injury and application thereof.
Background
The grassland resources of China are relatively rich and pay attention to the grassland resources all the time. However, due to excessive grazing and excessive reclamation, the phenomenon of desertification of the grassland is serious, and the phenomenon of degradation of the grassland is serious. In such cases, the rat damage is provided with a hotbed, which is rampant. Grassland rodents belong to social rodents, can continuously dig holes, and have strong gnawing capacity. Through constantly gnawing, can carry out destruction by a wide margin with secret root system, influence the healthy growth of forage grass from this. In addition, the grassland rodents have strong reproduction capability and no hibernation period. Under the condition that the environment is suitable for the growth of the rats, the propagation speed is gradually increased, and the rats become disasters after being propagated in large quantities, so that the grassland is damaged to different degrees. If the prevention and control force is insufficient, the damage of the rats cannot be effectively eliminated, vicious circle can be generated, and the ecological environment of the grassland is continuously destroyed. Therefore, attention needs to be paid to the control of the rat damage, and the control strength needs to be continuously improved.
By using chemical control measures, the method has the most outstanding advantages of being capable of taking effect in a short time and relatively wide in application range. 20.02 percent of diphen-barium sulfate bait registered by Liaoning Microbiol Engineers Limited company PD20102144 is a low-toxicity rodenticide which is prepared by mixing diphenoxylate and barium sulfate, has an action mechanism of promoting intestinal obstruction of pest rats to cause death of the pest rats, and has a good effect of preventing and treating the domestic rats. However, the control effect of 20.02% of dipheny-barium sulfate bait in the control of grassland rat damage is reduced to different degrees, and the reason for this is probably that the attractant in the chemical control of pest rats directly influences the preference degree of pest rats to a certain rodenticide, but the use of olfactory attractant must pay attention to the palatability of the bait used, so that the consumption can be increased after the attractant is used to attract rats. However, under certain conditions, olfactory attractants may translate into a strong antifeedant signal. The composite bait is mainly used abroad, namely, several raw materials are used at the same time, and the bait used in China is mixed according to a certain proportion and is single, so that the bait is probably not suitable for a few individuals. Meanwhile, the repeated use of the same bait, especially the short-term use of the bait, can enhance the food refusal, so that the killing effect is rapidly reduced, and the chemical control effect is seriously influenced. Therefore, the screening of the attractant becomes the key for developing the rodenticide.
Disclosure of Invention
The invention aims to provide a preparation for preventing and treating the rodent pests in grassland, which has excellent palatability and better prevention and treatment, and the specific technical scheme is as follows:
a preparation for preventing and treating rodent pests in grassland is characterized by comprising the following components, by weight, 0.005% -0.5% of diphenoxylate, 10% -30% of barium sulfate, 1% -30% of attractant and the balance of grain to 100%;
in the invention, the attractant consists of 1-10 parts by weight of vegetable oil, 0.5-5 parts by weight of plant essence, 0.5-3 parts by weight of amino acid, 0.5-5 parts by weight of oxalic acid, 1-8 parts by weight of salt and 1-25 parts by weight of saccharides.
In the invention, the vegetable oil is one or more of corn oil, peanut oil, rapeseed oil or sunflower oil; the plant essence is one or more of banana essence and pineapple essence; the amino acid is one or more of tryptophan, glutamic acid, leucine or serine; the salt is sodium chloride; the sugar is one or more of glucose and fructose; the grain is one or more of wheat, corn or rice.
In the invention, the vegetable oil is corn oil; the plant essence is one or more of banana essence and pineapple essence; the amino acid is one or more of glutamic acid and leucine; the salt is sodium chloride; the sugar is glucose.
The plant essence is a combination of banana essence and pineapple essence, and the mass ratio of the banana essence to the pineapple essence is 1; the amino acid is a combination of glutamic acid and leucine; the mass ratio of the two is 1.
The invention provides an application of a preparation for preventing and treating grassland mouse injury in preventing and treating the grassland mouse injury. The hamsters, gerbils and grassland yellowrats.
By adopting the technical scheme, the invention has the following beneficial effects:
compared with the known 20.02% diphen-barium sulfate bait, the bait prepared by selecting proper attractant has excellent palatability.
The bait prepared by the invention has a deratization effect obviously superior to that of a contrast medicament T7 under the same dosage, and the control effect of more than 80 percent can be achieved when the application amount of the medicament is 1.0kg/hm < 2 >.
Detailed Description
The present invention will be further explained with reference to specific embodiments.
Example 1: bait agent control grassland bandicoot field drug effect test report
1. Purpose of the experiment
And (3) screening an attractant capable of improving palatability to prepare the bait, and verifying the technical effect.
2. Test conditions
2.1 selection of test subjects, crops and varieties
Microtus brucei, chinchilla, prairie yellow mouse
Inner Mongolia typical grassland area (inner Mongolia autonomous area Silibin Guo Lei Meng AbaQin)
2.1 environmental conditions
The test area is not irrigated manually and mainly depends on natural rainfall. The test area topography is flat ground and gentle slope. The main vegetation in the test area is leymus chinensis, stipa capillata, a plurality of shallots, allium mongolicum regel and the like. The main pest species are the brucella, gerbil, grassland yellow rat, and the like, and the main pests are fighting for pasture with livestock, digging holes to destroy grassland vegetation, and the like. The natural enemies mainly include ferrets, hawks, falcon and the like.
3. Design and arrangement of experiments
3.1 test Agents
Table 1 drug formulation design
Control agent 7:20.02% dipheny barium sulfate bait (PD 20102144 registered by Liaoning Microbiol Engineers, inc.).
3.2 dosage and numbering of drugs
TABLE 2 test design of test agents
3.3 cell area and repetition
Cell area: 5 hectare/hectare
The number of repetitions: 0
3.4 methods of application
The using method comprises the following steps: in sunny weather, the bait is uniformly spread in the sample land, and 1 time of feeding is enough.
The application apparatus is as follows: plastic cup
Application time and times: spring 4 middle ten days of China, 1 broadcast application
4. Investigation, recording and measuring method
4.1 methods of investigation
Investigation of mouse density: according to the national standard (GB/T17980.68-2004), the density of the mice is investigated by adopting a hole plugging and stealing method. All rat wells of control and treatment zones were blocked before treatment and the number of stolen rat wells was investigated after 24h and the rat density was expressed as number of valid wells/hm 2.
And (4) bait feeding condition investigation: 20 feeding points were set up in each case, and bait stations were used as containers. After 150g of bait was added, the observation was continued for 3d. Bait consumption was recorded on each day.
4.2 method of calculating drug efficacy
4.3 direct effects on crops (not found), effects on other non-target organisms (not found)
5. Results and analysis
Statistical analysis of table 3 shows that the T1-T6 test agents consumed more bait than the control agent T7 on days 2 and 3, and that the T1-T6 increased consumption by 44.1%, 22.0%, 19.8%, 9.6%, 4.5%, 6.6% compared to the T7 agent treatment by day 3, respectively.
TABLE 3 statistic table of results of feeding coefficient test of phytochemicals for bait
The statistical analysis in Table 3 shows that the mouse killing effect of the T1-T6 bait with the same dosage is obviously better than that of a control medicament T7, and the control effect can reach more than 80% when the application amount of the medicament is 1.0kg/hm < 2 >.
TABLE 4 Experimental result statistics table for pesticide effect test of bait agent for preventing and treating grassland bandicoot
Example 2
20.05% of ground phenol-barium sulfate bait
0.05% of diphenoxylate, 20% of barium sulfate, 5% of corn oil, 0.4% of banana essence, 0.6% of pineapple essence, 0.2% of glutamic acid, 0.8% of leucine, 1.5% of oxalic acid, 5% of sodium chloride, 20% of glucose and the balance of grains to 100%.
30.1% of ground phenol-barium sulfate bait
0.1% of diphenoxylate, 30% of barium sulfate, 3% of corn oil, 0.8% of banana essence, 0.5% of glutamic acid, 0.5% of leucine, 3% of oxalic acid, 4% of sodium chloride, 18% of glucose and the balance of grains to 100%.
25.2% dipheny barium sulfate bait
0.2% of diphenoxylate, 25% of barium sulfate, 3% of peanut oil, 1.5% of banana essence, 0.8% of glutamic acid, 0.7% of leucine, 2% of oxalic acid, 4% of sodium chloride, 20% of glucose and the balance of grain to 100%.
Finally, it should be noted that: the above embodiments are only used to illustrate the technical solution of the present invention, and not to limit the same.
Claims (6)
1. A preparation for preventing and treating grassland mouse injury is characterized by comprising the following components, by weight, 0.005% -0.5% of diphenoxylate, 10% -30% of barium sulfate, 1% -30% of attractant and the balance of grain to 100%;
the attractant comprises 1-10 parts by weight of vegetable oil, 0.5-5 parts by weight of plant essence, 0.5-3 parts by weight of amino acid, 0.5-5 parts by weight of oxalic acid, 1-8 parts by weight of salt and 1-25 parts by weight of saccharides.
2. The formulation as claimed in claim 1, wherein the vegetable oil is one or more of corn oil, peanut oil, rapeseed oil or sunflower oil; the plant essence is one or more of banana essence and pineapple essence; the amino acid is one or more of tryptophan, glutamic acid, leucine or serine; the salt is sodium chloride; the sugar is one or more of glucose and fructose; the grain is one or more of wheat, corn or rice.
3. The formulation for controlling rodent pests of grassland according to claim 2, wherein the vegetable oil is corn oil; the plant essence is one or more of banana essence and pineapple essence; the amino acid is one or more of glutamic acid and leucine; the salt is sodium chloride; the sugar is glucose.
4. The formulation for controlling rodent damage in grasslands of claim 3, characterized in that the amino acid is a combination of glutamic acid and leucine.
5. An application of the preparation for preventing and treating the rodent pests in grassland.
6. The use according to claim 5, wherein said hamsters, chinchillas, prairie yellows.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202310106059.8A CN115968888B (en) | 2023-02-13 | 2023-02-13 | Preparation for preventing and controlling grassland mouse damage and application thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202310106059.8A CN115968888B (en) | 2023-02-13 | 2023-02-13 | Preparation for preventing and controlling grassland mouse damage and application thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN115968888A true CN115968888A (en) | 2023-04-18 |
| CN115968888B CN115968888B (en) | 2024-05-31 |
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| CN202310106059.8A Active CN115968888B (en) | 2023-02-13 | 2023-02-13 | Preparation for preventing and controlling grassland mouse damage and application thereof |
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Citations (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1118652A (en) * | 1994-05-10 | 1996-03-20 | 浙江省粮食科学研究所 | Safety mouse killing bait |
| CN1242934A (en) * | 1998-07-29 | 2000-02-02 | 周良勇 | Toxinless chemical for rat eradication |
| CN1352879A (en) * | 2001-11-27 | 2002-06-12 | 朱天相 | Biochemical rodenticide |
| JP2003212701A (en) * | 2002-01-16 | 2003-07-30 | Earth Chem Corp Ltd | Poison bait for rat and method for stabilizing the same |
| JP2003292404A (en) * | 2002-02-04 | 2003-10-15 | Earth Chem Corp Ltd | Poisonous feed agent against rat and method for stabilizing the same |
| US20080260683A1 (en) * | 2004-01-30 | 2008-10-23 | Gary Raymond Bowman | Rodenticide |
| CN102187883A (en) * | 2010-12-08 | 2011-09-21 | 单承仪 | Nontoxic type high expansion solidification lethal rodent bait and preparation method thereof |
| CN112806366A (en) * | 2021-01-11 | 2021-05-18 | 四川益万家环境工程有限公司 | Efficient, environment-friendly and nontoxic rat killing medicine |
| CN115005235A (en) * | 2022-06-28 | 2022-09-06 | 辽宁微科生物工程有限公司 | Microbial rodenticide |
-
2023
- 2023-02-13 CN CN202310106059.8A patent/CN115968888B/en active Active
Patent Citations (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1118652A (en) * | 1994-05-10 | 1996-03-20 | 浙江省粮食科学研究所 | Safety mouse killing bait |
| CN1242934A (en) * | 1998-07-29 | 2000-02-02 | 周良勇 | Toxinless chemical for rat eradication |
| CN1352879A (en) * | 2001-11-27 | 2002-06-12 | 朱天相 | Biochemical rodenticide |
| JP2003212701A (en) * | 2002-01-16 | 2003-07-30 | Earth Chem Corp Ltd | Poison bait for rat and method for stabilizing the same |
| JP2003292404A (en) * | 2002-02-04 | 2003-10-15 | Earth Chem Corp Ltd | Poisonous feed agent against rat and method for stabilizing the same |
| US20080260683A1 (en) * | 2004-01-30 | 2008-10-23 | Gary Raymond Bowman | Rodenticide |
| CN102187883A (en) * | 2010-12-08 | 2011-09-21 | 单承仪 | Nontoxic type high expansion solidification lethal rodent bait and preparation method thereof |
| CN112806366A (en) * | 2021-01-11 | 2021-05-18 | 四川益万家环境工程有限公司 | Efficient, environment-friendly and nontoxic rat killing medicine |
| CN115005235A (en) * | 2022-06-28 | 2022-09-06 | 辽宁微科生物工程有限公司 | Microbial rodenticide |
Non-Patent Citations (2)
| Title |
|---|
| 无: "20.02%地芬•硫酸钡饵剂", Retrieved from the Internet <URL:www.chinapesticide.org.cn/zwb/dataCenter> * |
| 韩崇选 等: "安全型无公害灭鼠剂—克鼠星的研究", vol. 17, no. 3, 5 September 2002 (2002-09-05), pages 44 - 47 * |
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| CN115968888B (en) | 2024-05-31 |
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