CN1158734A - Cigariete-type medicine for curing tracheitis and asthma and its production process - Google Patents

Abstract

Cigarette-type Chinese medicine is prepared with Chinese medicinal material and food material including almond, peach kernel, orange peel, Dityophora phalloidea, etc. and it has no tobacco and no nicotine. It is inhaled through mouth and nose into trachea and pulmonary cavity to cure tracheitis, asthma, pulmonary emphysema and other pulmonary diseases. The medicated aerosol produced during cure has certain prevention and cure effect on pulmonary diseases.

Description

The non-medicated cigarette and the production method thereof that contains nicotine of treatment tracheitis, asthma

The present invention relates to treat the Chinese medicine of people's lung pattern disease, especially be a kind of medicated cigarette of making by certain ingredients, proportioning, technology without Nicotiana tabacum L. medicine, foodstuff material that can treat diseases such as tracheitis, asthma, this medicated cigarette does not contain harmful nicotine material, and medical convenience, rapid-action, good effect.

Spring, summer, autumn and winter throughout the year, because of seasonal variations, cold and hot variation people often cause the generation of diseases such as lung pattern disease such as tracheitis, asthma, emphysema, especially in autumn and winter season, the number of sickness rate height, morbidity is also many.According to interrelated data report, the people that lung pattern diseases such as cough, asthma, bronchitis, emphysema are suffered from by China has people more than 100,000,000, in case after sick the sending out, cough more than, uncomfortable in chestly feel bad, inappetence, the late into the night can not fall asleep, be in extreme agony.

Got the patient of tracheitis, asthma, and had weak point aspect medicine for treatment: oral medication, lung are that the trachea absorption is slow, sick needs two weeks once violating--and took medicine constantly in 1 month, and ate medicine time one length of controlling this disease, stomach does not feel well; Have an injection: as intramuscular injection, intravenously administrable, operation is numerous and diverse, and the patient is difficult for accepting, and sometimes, injection technique is poor, and the patient feels pain, and efficacy of a drug onset is also slow.

The objective of the invention is to overcome the weak point in the above prior art, and provide a kind of people in rapid-action after the lung pattern disease medication, the dispenser process are not agonized, be easy to accept, do not contain tobacco leaf ingredient, do not contain the medicated cigarette and the production method thereof of harmful nicotine material.

Formation of the present invention:

(1): the origin of the medicated cigarette of treatment lung pattern disease:

" medicine origin " smelt in medicine one joint and pointed out: " medicine gas is through lung from the nostril, and by passing through arteries and veins, all over the body thorough, the acute disease severe and lingering illness is used it from disease, takes medicine can't be obtained to help "; I (Zhang Zhongying) is engaged in traditional Chinese medical science work for many years in county institute of traditional Chinese medicine, thinks: " lung governing qi, department breathes; towards the physiological characteristics of hundred arteries and veins, and carbon monoxide poisoning, and mechanism such as disease are treated in oxygen uptake; recognize that sucking deleterious material can make the people cause a disease, otherwise, suck useful material and also one make people's physique enhancing and disease treating surely ".By this mechanism, relevant medicine processing and refining is become " cigarette ", with smoking regime, point so adds temperature rise and turns to the medicine mist, and the through port snuffing is gone into, and sees through respiratory membrane rapidly, enters pulmonary vein, arrives the left heart, transports the whole body, brings into play effect at once.Or clothing invests trachea and the arteries and veins bubble is surperficial, directly treats disease, and protects and defend exopathogen to attack again, and gradual slow sucks, and brings into play therapeutical effect for a long time.Here it is is processed into the cause that cigarette (medicated cigarette) is treated lung pattern disease to medicine, food substance.

Treat in the process of tracheitis, asthma at the research medicated cigarette, doubt is also arranged at heart--country carries prosperous public's field boundary and closes ban on opium-smoking and the opium trade, harm of smoking ... in, oneself studies medicated cigarette is suitable for after thinking better of repeatedly, it is suitable to assert, reason is: (1), same Chinese medicine ingredients are developed into powdery medicine, graininess medicine, capsule shape medicine or medicine administered by injection (liquid state), for people's respiratory tract, lung pattern disease, treat in the disease process in dispenser, medicated cigarette (cigarette) plays fast, the good effect of drug effect fruit; (2), long-time oral powdery medicine or graininess medicine or capsule shape medicine, easily regurgitation; Medicine administered by injection (liquid state): muscle or intravenous injection trouble (3), suffer from the people of lung pattern diseases such as tracheitis, asthma, have considerable people that the habit of smoking is arranged, be acceptant if smoke the medicated cigarette (cigarette) that does not contain Nicotiana tabacum L., do not contain nicotine; (4), pipeline, fast, the good effect of lung intracavity curative effect are gone in the snuffing of medicated cigarette through port.In treating the disease process, for being dispersed in the air: the smog of medicated cigarette, smoke, to the people who suffers from lung pattern disease is exactly not inhale medicated cigarette and certain curative effect effect is also arranged, and is the inspirator of disease for apneumia, also harmless (not the containing harmful nicotine material in smog, the smoke) that can prevent.

(2), the composition of the medicated cigarette of treatment lung pattern disease:

Semen Armeniacae Amarum, Semen Persicae, Pericarpium Citri Reticulatae, Mel, Caulis Bambusae In Taenia, water

Following division it:

(1), Semen Armeniacae Amarum (formal name used at school), be the seed of rosaceae plant deciduous tree's Prunus armeniaca L.var.ansu Maxim., gather when ripe summer, dries peeling and use.A prescription name Semen Armeniacae Amarum.Nature and flavor: bitter, tepor.Return lung, large intestine channel.Effect: relieving cough and asthma, loosening bowel to relieve constipation.Contain amygdalin, emulsin and Semen Armeniacae Amarum oil.Amygdalin produces hydrocyanic acid after enzyme hydrolysis, micro-hydrogen cyanogen can suppress respiratory center, makes respiratory movement be tending towards quiet and play function of relieving cough and calming asthma.(2), Semen Persicae (formal name used at school) is for taking fruit after the kind maturation of Rosaceae defoliation small arbor Semen Persicae, taking out seed, dries use.Nature and flavor: hot, bitter, flat.Return liver, lung, large intestine channel.Effect: blood circulation promoting and blood stasis dispelling, loosening bowel to relieve constipation, relieving cough and asthma.Contain amygdalin, emulsin, fatty oil, volatile oil, vitamin B ₁Deng.(3), Pericarpium Citri tangerinae (formal name used at school) is the skin of the mature fruit of the evergreen dungarunga plant of Rutaceae tangerine, collect autumn, dries living usefulness, is good with Chen Jiuzhe, prescription is with a name Pericarpium Citri Reticulatae.Nature and flavor: hot, bitter, warm.Return spleen, lung meridian.Effect: circulation of qi promoting spleen invigorating, drying dampness to eliminate phlegm, stopping nausea and vomiting by lowering the adverse flow of QI.Contain volatile oil, main component is limonene, Gou Ca aldehyde, hesperetin, hesperidin, inositol, vitamin B in the oil ₁Deng.Pericarpium Citri Reticulatae volatile oil has demulcent stimulation to digestive tract, helps the discharge of gastrointestinal pneumatosis; Can impel gastric secretion, help digestion.Can stimulate respiratory mucosa, make secretions increase, the sputum dilution helps discharging; Hesperetin can expansion bronchus and show antiasthmatic effect.(4), Mel, be Mel section apis cerana, the glucide that in beehive, leads to.Normally thin up, boil, elimination impurity, reconcentration forms.The prescription name, Mel.Nature and flavor: sweet, flat.Return lung, spleen, large intestine channel.Effect: loosening bowel to relieve constipation, nourishing the lung to arrest cough, tonifying the stomach and spleen." herbal classic ": " main trusted subordinate's pathogen, Zhu Jing Epilepsy convulsion, settling five organs, various symptoms and signs of deficiency, remove all kinds of diseases and ailments and hundred medicines, obey strong will for a long time at QI invigorating invigorating middle warmer, pain relieving, detoxifcation." " not Lu ": " support temper, remove vexed ".Compendium of Material Medica: its merit of being used as medicine has five, heat clearing away also, invigorating middle warmer also, detoxifcation also, moisturize also, pain relieving also.Contain fructose, glucose, sucrose, inorganic salt, enzyme, protein, stifled, pigment, pollen grain, aroma substance etc.In vitro tests, Mel has bactericidal action,, stops action after 5 minutes, promptly is killed in 20 minutes in 5% honeydew as dysentery bacterium and pyococcus.Being food but also being the kind of medicine of " be food be medicine not only " that aforementioned (1), (2), (3), (4) belong to " the food composition tables " that the Pharmacopoeia of the People's Republic of China 85 editions and Chinese Academy of Medical Sciences's health institute write (1981 third edition, wild herbs class except) and on April 16th, 1988, Ministry of Public Health Food Hygiene Surveillance check institute, (88) food prison word No. 23 is so life-time service has no side effect.(5), Caulis Bambusae In Taenia (formal name used at school) is grass family arbor or shrub plant phyllostachys nigra (lodd.ex lindl.) munro var.henonis (miff.) spapf et rendle, removes the fiber that green layer back scraped.The prescription name, Caulis Bambusae In Taenia.Nature and flavor: sweet, be slightly cold.Return lung, stomach, gallbladder meridian.Effect: the heat clearing away disease, relieve restlessness and prevent vomiting.(data with reference to, national high medical college teaching material on probation, July in 1981 the 2nd printed book).

(3), the proportioning and the production method of the medicated cigarette of treatment lung pattern disease:

1, proportioning: (percentage by weight)

Semen Armeniacae Amarum 5--10%

Semen Persicae 5--10%

Pericarpium Citri Reticulatae 45--55%

Caulis Bambusae In Taenia 25--35%

Mel 10--15%

Water is an amount of

2, production method (referring to technological process of production figure):

Production method: A, select materials: with first-class good merchantable brands of buying such as Semen Armeniacae Amarum, Semen Persicae, Pericarpium Citri Reticulatae, Caulis Bambusae In Taenia, screening-roguing, respectively by the standard infusion, B, in proper order, (1), Pericarpium Citri Reticulatae, Caulis Bambusae In Taenia being pressed the proportional quantity republicanism stirs or stirs separately, be processed into thick 0.03--0.05 with spatula or filament cutter, wide 0.1-0.12, long 1--5 centimetre specification.(2), Semen Armeniacae Amarum, Semen Persicae screen republicanism respectively by proportional quantity and stir, and pulverized 80 mesh sieves with pulverizer.(3), (1) is mixed stirring with (2).(4) Mel adds water 4--6 part for 1 part and mixes stirring, with stirring in the nebulization spirt (3), promptly available paper roll is wrapped up in (craft or machinery all can) and is become 0.7 centimetre of diameter, and long 9 centimetres garden cylindricality is then with long 7 centimetres of cutter or cutting machine shaping cutting, shape such as cigarette shape, refill and connect filter tip and get final product, every heavily about 1 gram, oven dry or wind shine temperature at 15--35 ℃, 4--10 hour, be up to the standards encapsulation, warehouse-in.

Water in composition (in right amount), because of in production process, adding, at finished product--disappear again in medicated cigarette (cigarette) oven dry before, so in composition proportion, do not count in the shared percentage by weight of water.

This medicated cigarette is the Chinese medicine composition that does not contain Nicotiana tabacum L., do not contain the nicotine material, the garden post cigarette shape that is shaped as non-powdery, non-particulate shape, non-capsule shape of its medicated cigarette.

This medicated cigarette is progressively produced by following a.b.c.d.e.f:

A, Pericarpium Citri Reticulatae, the Caulis Bambusae In Taenia of choosing screened respectively remove impurity, the water that then mixes and add trace makes it moistening, and then artificial or machine is cut into the tobacco shred shape;

B, Semen Persicae, Semen Armeniacae Amarum are screened respectively, mix, then pulverize, sieve;

C, mix, stir adding an amount of water in the Mel;

D, with a.b.c thing mixing and stirring;

E, the mixture that stirs is carried out Medicated cigarette and is cut into cigarette segments with paper;

F, oven dry: temperature needs to dry 4--10 hour at 15--35 ℃.

Embodiment 1: Semen Armeniacae Amarum 5Kg, and Semen Persicae 5Kg, Pericarpium Citri Reticulatae 48Kg, Caulis Bambusae In Taenia 30Kg, Mel 12Kg, water: an amount of, produce by aforementioned technology.The medicated cigarette of being produced is an I type medicated cigarette.

Embodiment 2: Semen Armeniacae Amarum 7Kg, and Semen Persicae 7Kg, Pericarpium Citri Reticulatae 47Kg, Caulis Bambusae In Taenia 25Kg, Mel 14Kg, water: an amount of, producing the medicated cigarette of being produced by aforementioned technology is II type medicated cigarette.

Above-mentioned II type medicated cigarette is better than I type medicated cigarette on curative effect.

The function of medicated cigarette, cure mainly: function smoking cessation diseases prevention, public health care, blood circulation promoting and blood stasis dispelling, inducing menstruation to relieve menalgia, activating QI to eliminate phlegm, relieving cough and asthma, the relieving restlessness disease that disappears, help think to separate excellent.Cure mainly respiratory illnesses such as tracheitis, asthma, emphysema, reach the refreshing labor disease of being stranded, medicated cigarette hobby, unhappy melancholy and qi depression to blood stasis, the strongly fragrant resistance medicated cigarette of phlegm-damp sexually transmitted disease (STD) disease.

After medicated cigarette is succeeded in developing, test (treatment disease) through user " inside ":

Effect: observe through clinical 93 examples,, light suction 3--5 breath (exhales a suction to be one expiration and inspiration) and can take effect indication,--symptom is alleviated substantially in the time of 1.(1) treatment pain, onset time ratio dispel 3--5 such as oral medicine raising the such as pain sheet etc. doubly.(2) loudspeaker is coughed in treatment, onset time than Radix Glycyrrhizae tabellae, carbetapentane citrate, happyly cough oral medicine such as clean and improve 5--10 doubly.(3) treatment asthma, onset time is improved 3--5 doubly than oral medicines such as aminophylline, salbutamols; Improve 2--3 doubly than the quiet notes of aminophylline; Suck raising 1--2 doubly than clenbuterol aerosol.(4) reduce phlegm onset time doubly, and spit similar sputum aspirator immediately after sucking than raising 5--10 such as fresh Succus Bambusae, TANJING.Especially this inhalating the smoke of burning drugs is all more safe and reliable than medications such as oral, intramuscular injection, veins, has rapid-actionly, easy to use, welcome by the patient.

Utilize medicated cigarette to prevent curing the disease, for a new route of administration has been opened up in the Chinese medicine dispenser.

Claims (2)

1, a kind of non-medicated cigarette that contains nicotine for the treatment of tracheitis, asthma, it is characterized in that: this medicated cigarette is the Chinese medicine composition that does not contain Nicotiana tabacum L., do not contain the nicotine material, it is made up of with material such as Semen Armeniacae Amarum, Semen Persicae, Pericarpium Citri Reticulatae, Caulis Bambusae In Taenia, Mel and an amount of water medicine, food, the percentage by weight of its composition is: Pericarpium Citri Reticulatae 45--55%, Caulis Bambusae In Taenia 25--35%, Semen Persicae 5--10%, Semen Armeniacae Amarum 5--10% Mel 10--15, water, in right amount, the garden post cigarette shape that is shaped as a kind of non-powdery, non-particulate shape, non-capsule shape of its medicated cigarette.

2, the production method of medicated cigarette according to claim 1 is characterized in that: this cigarette is progressively produced by following a.b.c.d.e.f then:

A, Pericarpium Citri Reticulatae, the Caulis Bambusae In Taenia of choosing screened respectively remove impurity, the water that then mixes and add trace makes it moistening, and then artificial or machine is cut into the tobacco shred shape;

B, Semen Persicae, Semen Armeniacae Amarum are screened respectively, mix, then pulverize, sieve;

C, mix, stir adding an amount of water in the Mel;

D, with a.b.c thing mixing and stirring;

E, the mixture that stirs is carried out Medicated cigarette and is cut into cigarette segments with paper;

F, oven dry: temperature needs to dry 4--10 hour at 15--35 ℃.

Images