CN115804745A - Skin care and soothing repair composition and application thereof - Google Patents

Skin care and soothing repair composition and application thereof Download PDF

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Publication number
CN115804745A
CN115804745A CN202211691888.9A CN202211691888A CN115804745A CN 115804745 A CN115804745 A CN 115804745A CN 202211691888 A CN202211691888 A CN 202211691888A CN 115804745 A CN115804745 A CN 115804745A
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extract
skin
composition
skin care
acid
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陈思阳
朱超凡
徐小建
潘美红
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Guangzhou Natural State Biotechnology Co ltd
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Guangzhou Natural State Biotechnology Co ltd
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Priority to CN202211691888.9A priority Critical patent/CN115804745A/en
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Abstract

The invention belongs to the technical field of cosmetics and discloses a skin care and soothing repair composition which comprises 90 wt% of edelweiss extract, 5-9 wt% of oat beta-glucan and 1-5 wt% of olive leaf extract. Also discloses application of the skin care and soothing repairing composition after acid brushing, wherein the addition amount of the composition in a skin care product is 1-2wt%. The skin care soothing and repairing composition can relieve and repair the problems of dryness, tightness, desquamation, sensitivity, barrier damage and the like of the acid brushed skin, and simultaneously improves the tolerance of the acid brushed skin.

Description

Skin care and soothing repairing composition and application thereof
Technical Field
The invention belongs to the technical field of cosmetics, and particularly relates to a skin care and soothing repairing composition and application thereof.
Background
Acid brushing is a chemical skin rejuvenation method, which uses a certain concentration of acid to promote the exfoliation of the stratum corneum. The acid component has solubility, and can peel off old waste cutin and accelerate skin metabolism. The brushing acid can control grease secretion, remove grease and dirt in pores, relieve pore blockage, specifically solve the problems of blackheads, acnes, closed mouths, acnes and the like, can inhibit the generation of melanin, and can play a certain role in whitening, removing freckles and acne marks. Has good effects on skin aging such as dark skin, large pore, acne skin, closed comedo, acne mark skin, pigmentation after inflammation, acne rosea, seborrheic dermatitis, peritrichogenous keratosis, etc.
With the improvement of living standard, the continuous enhancement of beauty consciousness and the continuous pursuit of beauty, the acid brushing is not exclusive to the department of medical skin cosmetology and beauty institutions, and a large number of acid skin care products appear in the market, so that the public can use the acid brushing product more conveniently. However, when the acid product is used frequently and in high concentration, adverse reactions such as dry and tight skin, desquamation, sensitivity, erythema and the like are easy to occur after acid brushing, and even more serious patients have symptoms such as blisters, ulcerations, pigmentation and the like, so that the skin is greatly damaged.
In the prior art, the skin care product has single relieving effect after acid brushing, and has the defect of treating symptoms and not treating the root causes. At present, the mainstream anti-allergy relieving skin care product can only inhibit symptoms such as redness, stabbing pain and itching after acid brushing, or can improve moisturizing effect to achieve repairing effect, but only solves symptoms such as redness, stabbing pain and itching on the surface or only moisturizes and can only temporarily relieve the stimulation on the skin, and cannot fundamentally solve the problems of skin barrier damage and poor tolerance after acid brushing.
D1: CN113144039A discloses a plant anti-allergy relieving composition, a preparation method and an application thereof, wherein the plant anti-allergy relieving composition comprises the following raw materials: plant component A, plant component B and pine needle mill strain; wherein the plant component A is alpine edelweiss or oldenlandia diffusa, and the plant component B is rehmannia or andrographis paniculata.
In application example 1, oat beta-glucan was also added to the formulation.
D2: CN110859791B is a skin whitening composition, application thereof and a skin whitening mask, wherein the skin whitening composition comprises the following components: snow lotus herb extract, alpine edelweiss extract, reed extract, licorice root extract, angelica root extract, salvia miltiorrhiza root extract, dogwood fruit extract, wolfberry root extract, peach resin extract, astragalus membranaceus root extract, divaricate saposhnikovia root extract, calendula extract, albizia flower extract and gastrodia tuber root extract.
The specification states: the skin whitening composition further comprises one or more of niacinamide and oat beta-glucan.
The skin whitening composition has the allergy relieving effect, can repair damaged skin, prevent skin allergy and form an effective skin protection barrier.
D3: CN107970203A discloses a biological fermentation skin lotion and a preparation method thereof, comprising a component A, a component B and a component C; the component A comprises the following raw materials in parts by weight: 50-70 parts of bacillus/glutamic acid fermentation product filtrate, 15-25 parts of water, 0.05-0.2 part of sodium hyaluronate, 1-3 parts of glycerol, 1-4 parts of glycerol polymethacrylate, 1-3.5 parts of diglycerol and 0.04-0.08 part of EDTA disodium; the component B comprises the following raw materials in parts by weight: 2-5 parts of oat beta-glucan, 1-4.5 parts of edelweiss extract, 0.5-3.5 parts of porphyridium extract, 10.0005-0.002 parts of oligopeptide and 1-4 parts of citrus extract; the component C comprises the following raw materials in parts by weight: 1 to 4 parts of glycerol, 0.05 to 2 parts of 1, 2-pentanediol and 0.1 to 0.5 part of ethylhexyl glycerol.
The specification thereof describes: the component B comprises the following raw materials in parts by weight: 2 to 5 parts of oat beta-glucan, 1 to 4.5 parts of alpine edelweiss extract, 0.5 to 3.5 parts of porphyridium extract, 0.0005 to 0.002 part of oligopeptide-1.002 part and 1 to 4 parts of citrus extract.
D4: CN110191895A discloses compounds useful for treating and/or caring skin, hair, nails and/or mucous membranes, the specification of which discloses that a cosmetic or pharmaceutical composition may comprise a cosmetically or pharmaceutically effective amount of at least one anti-wrinkle and/or anti-aging agent selected from the group consisting of extracts or hydrolyzed extracts of, for example, but not limited to, vitis vinifera (Vitis vinifera), rosa canina (Rosa canina), curcuma longa (Curcuma longa), cacao (Theobroma cacao), ginkgo biloba (Ginkgo biloba), leontopodium alpinum (Leontopodium alpinum) or Dunaliella salina (Dunaliella salina), etc., citrus (Citrus Sinensis) fruit water, rice extract, acronychia SPINOSA (capris SPINOSA) fruit extract, olive leaf extract ], marketed by Bionap; [ INCI: carbohydrate hydrolysates ], sold by laboratories Expanscience; arbutin and isomers thereof, kojic acid and derivatives thereof, vitamin C and derivatives thereof, such as but not limited to 6-O-palmitoyl ascorbic acid, dipalmitoyl ascorbic acid, magnesium salts from ascorbic acid-2-phosphate (MAP), sodium from ascorbic acid-2-phosphate (NAP), ascorbyl glucoside or ascorbyl tetraisopalmitate (VCIP) and the like, retinol and derivatives thereof, including retinoic acid and isotretinoin, idebenone, hydroxybenzoic acid and derivatives thereof, flavonoids, soy extracts, lemon extracts, orange extracts, ginkgo extracts, cucumber extracts, geranium extracts, bearberry extracts, carob extracts, cinnamon extracts, marjoram extracts, rosemary extracts, clove extracts, licorice soluble extracts, blackberry leaf extracts, niacinamide, liquiritin, resorcinol and derivatives thereof, hydroquinone, alpha-tocopherol, gamma-tocopherol, azelaic acid, resveratrol, mercurite, linoleate, alpha-lipoic acid, dihydrolipoic acid, alpha hydroxy acids, beta-hydroxy acids, ellagic acid, cinnamic acid, a ferulic acid inhibitor, a 2-tocopherol, a gamma-tocopherol, a cinnamic acid inhibitor, a trypsin inhibitor, a PAR-like, or a mixture thereof.
The cosmetic or pharmaceutical composition of the invention may comprise a cosmetically or pharmaceutically effective amount of at least one compound, oil or wax selected from cosmetic or pharmaceutical adjuvants formed from moisturizers (moisture retaining substances), moisturizers and emollients, such as, but not limited to, polyols and polyethers such as glycerol, ethylhexylglycerin, octanediol, pentanediol, butanediol, propanediol and its derivatives, triethylene glycol, polyethylene glycol, glycereth-26, sorbeth-30; panthenol; pyroglutamic acid and salts or derivatives thereof; amino acids such as serine, proline, alanine, glutamic acid or arginine; ectoin (ectoin) and its derivatives; n- (2-hydroxyethyl) acetamide; pyrrolidinone carboxylic acidAcid (PCA); n-lauroyl-pyrrolidone carboxylic acid; N-lauroyl-L-lysine; n- α -benzoyl-L-arginine; urea; creatine; alpha-and beta-hydroxy acids such as lactic acid, glycolic acid, malic acid, citric acid, tartaric acid or salicylic acid and salts thereof; polyglycerol acrylate; sugars and polysaccharides, such as glucose, the isomeric sugars, sorbitol, pentaerythritol, inositol, xylitol, sorbitol, trehalose and derivatives thereof, sodium glucuronate, carrageenan (Chondrus crispus) or chitosan; glycosaminoglycans such as hyaluronic acid and derivatives thereof; aloe in any form; honey; soluble collagen; lecithin and phosphatidylcholine; a ceramide; cholesterol and esters thereof; tocopherols and esters thereof, such as tocopheryl acetate or tocopheryl linoleate; long-chain alcohols such as cetostearyl alcohol, stearyl alcohol, cetyl alcohol, oleyl alcohol, isohexadecyl alcohol or octadecan-2-ol; long chain alcohol esters such as lauryl lactate, myristyl acetate or C 12 -C 15 Alkyl benzoate esters; fatty acids such as stearic acid, isostearic acid or palmitic acid; polyunsaturated fatty acids (PUFAs); sorbitan such as sorbitan distearate; glycerides such as glycerol monoricinoleate, glycerol monostearate, glycerol stearate citrate or caprylic and capric triglycerides; sucrose esters such as sucrose palmitate or sucrose oleate; butanediol esters such as dicaprylate and dicaprate; fatty acid esters such as isopropyl isostearate, isobutyl palmitate, isohexadecyl stearate, isopropyl laurate, hexyl laurate, decyl oleate, cetyl palmitate, di-n-butyl sebacate, isopropyl myristate, isopropyl palmitate, isopropyl stearate, butyl myristate, isopropyl linoleate, 2-ethylhexyl palmitate, 2-ethylhexyl cocoate, decyl oleate, myristyl myristate; squalene; mink oil; lanolin and its derivatives; acetylated lanolin alcohol; organosilicon derivatives such as cyclomethicone, dimethicone or dimethylpolysiloxane; [ INCI: pseudoalteromonas fermentation product extract]And [ INCI: glycerol, pseudoalteromonas fermentation product extract, xanthan gum, proline, alanine, serine, ethylhexyl glycerol, and octyl glycol]And [ INCI: acetyl dipeptide-3 aminohexanAcid esters]And [ INCI: pseudoalteromonas fermentation product extract]Or [ INCI: acetyl hexapeptide-37]Sold by Lipotec/Lubrizol; ER [ INCI: glycerol, extract of fermentation product of Pomegranate (PUNICAGRANATUM) fruit]And [ INCI: extract of Padina PAVONICA (Padina PAVONICA) thallus]Or Phytoamine Biocomplexe [ INCI: comfrey Extract (Symphytum Officinale Extract), plantago OVATA (Plantago OVATA) seed Extract, hydrolyzed wheat protein, glutamine, proline, leucine, serine]Sold by Alban Muller; dermaclarine TM [ INCI: hydrolyzed egg protein, protease]Marketed by Aqua Biotechnology; bio-Plex NMF [ INCI: sodium PCA, lactic acid, sodium lactate, urea, collagen amino acids]And [ INCI: urea, yeast amino acids, trehalose, inositol, taurine, betaine]Or ReGeniStem TM RedRice [ INCI: ozone-treated Rice (Rice) callus culture extract]Sold by Arch/Lonza; hydralphatine TM Asia [ INCI: hydrogenated starch hydrolysate, panthenol, bamboo shoot extract of Bambusa VULGARIS (BAMBUSA VULGARIS), flos Nelumbinis (NELUMBO NUCIFERA) extract, and radix Nymphaeae (Nymphaea ALBA) extract]And [ INCI: glucosamine, SCLEROTIUM rolfsii (scleroticum ROLFSSII) gum]，Hydraporine TM [ INCI: betaine, hydrogenated lecithin, honey, pectin]Or Exo-H TM [ INCI: alteromonas fermentation product extract]Sold by Lucas Meyercosmetics/Unipex; patch 2 O TM [ INCI: trehalose, urea, serine, glycerol polyacrylate, algin, sodium hyaluronate, pullulanase polysaccharide]Sold by BASF; cellike [ INCI: caprylic/capric triglyceride, hydrogenated phosphatidylcholine, shea butter (Butyrrospermum PARKII), phytosterol, caprylin, ceramide NP]Marketed by BioSpectrum; [ INCI: extract of Tiger skin (Piptadenia Colubrina Peel)]Sold by cheyunion; dayMoist TM CLR [ INCI: hydrolyzed corn starch, extract of beet (BETA Vulgaris) root]Sold by CLR; hydranov [ INCI: sodium carrageenan, sea salt]Or Hydrasalinol [ INCI: extract of Salicornia HERBACEA (Salicornia HERBACEA), caprylic/capric triglyceride]Sold by Codif; marine FillingSpheres TM [ INCI: pentaerythritol tetraisostearate, bisSilica methylsilylate, sodium chondroitin sulfate, atelocollagen]Sold by Coletica/Engelhard/BASF; [ INCI: hyaluronic acid sodium salt]Or [ INCI: ceteareth-25, cetyl alcohol, behenic acid, cholesterol, ceramide NP, ceramide NS, ceramide EOS, ceramide EOP, ceramide AP, caproyl phytosphingosine, caproyl sphingosine]Sold by Evonik; DS-Sphyngomilin M [ INCI: sphingolipid]Marketed by Doosan; syn-Up TM [ INCI: benzylsulfonyl D-seryl homophenylalanine amidinobenzamide acetate]Sold by DSM; [ INCI: hydrolyzed Acacia (Acacia Macrostachya) seed extract]Or [ INCI: unsaponifiable sunflower (Helianthus Annuus) seed oil]Sold by laboratories Expanscience; [ INCI: chondrus Crispus (Chondrus Crispus) extract]Or [ INCI: glutaminylethylindoles]Sold by Exsymol; boniel TM [ INCI: lactobacillus fermentation product]Sold by Ganeden Biotech; renew [ INCI: cryptomeria JAPONICA (Cryptomeria JAPONICA) bud extract]Sold by gattefosse; [ INCI: lactobacillus fermentation lysate]Sold by Greentech; aqua Shuttle [ INCI: sorbitol, laminaria digitata (Laminaria digitata) extract, and diatomaceous earth]Sold by Infinitec; aquarize TM IS [ INCI: hydrolyzed rice extract]Or Aqua-Osmoline TM [ INCI: extract of Carob seed]Sold by Vincience/ISP/Ashland; aqu' activ TM [ INCI: behenyl alcohol, glyceryl oleate, cocamide MIPA]HP [ INCI: seed extract of coffee yellow sunflower (HIBISCUS ESCULENTUS)]And [ INCI: cassia angustifolia (Cassiaangusttifolia) seed polysaccharide]CA [ INCI: cassia ANGUSTIFOLIA (Cassia ANGUSTIFOLIA) seed polysaccharide]And [ INCI: octyldodecanol, irvingia GABONENSIS nut butter, hydrogenated coconut oil glycerides]And [ INCI: octyl dodecanol, arachidyl alcohol propionate, tocopheryl acetate, retinol palmitate, ethyl linoleate, ethyl linolenate]Or SU [ INCI: sorbitol, seaweed extract, chondrus Crispus (Chondrus Crispus), fucus vesiculosus extract, algin]Sold by l.serobioliques/Cognis/BASF; lipocare HA/EC [ INCI: sodium hyaluronate and echinine]Sold by lipophemics; hydro-Gain TM [ INCI: low erucic acid rapeseedOil, hydrogenated lecithin, opuntia ficus-indica seed oil, and Betula ALBA bark extract]Sold by lipoid kosmetik; renouMer [ INCI: seaweed extract]Sold by Merck; aquaCacteen [ INCI: stem extract of Opuntia FICUS-INDICA (Opuntia FICUS-INDICA)]Snow Algae Powder [ INCI: extract of snow algae (Coenochloris Siniensis)]Or Trimoist KMF [ INCI: sodium stearoyl lactylate, cetyl alcohol, vegetable oil, tocopherol acetate, glycine SOJA sterols, sodium carboxymethyl beta-glucan, sodium lactate, carnosine, lactic acid]Sold by Mibelle; nectapture [ INCI: thyme flower/leaf extract, buddleja DAVIDII (Buddleja DAVIDII) extract]。
The following conclusions can be drawn from the above comparison documents:
1. edelweiss extract, oat beta-glucan are commonly used soothing compositions;
2. the extract of Leontopodium alpinum and the extract of Olea europaea leaf can be used as anti-wrinkle and anti-aging active substances.
The technical problem solved by the scheme is as follows: how to further improve the anti-allergy soothing effect so as to improve the comfort to the skin with poor tolerance.
Disclosure of Invention
In view of the deficiencies of the prior art, it is a first object of the present invention to provide a care composition that substantially solves the problem of impaired skin barrier and poor tolerability after brushing acid. The invention provides a skin care soothing and repairing composition, which is used for soothing and repairing the problems of dryness, tightness, desquamation, sensitivity, barrier damage and the like of the acid brushed skin and improving the tolerance of the acid brushed skin.
A second object of the present invention is to provide the use of the above skin care soothing rejuvenating composition.
In order to achieve the first invention purpose, the invention adopts the following technical scheme: a skin care soothing and rejuvenating composition comprising an extract of Leontopodium alpinum, oat beta-glucan, olive leaf extract.
Further, the skin care and soothing repairing composition comprises 90 wt% of leontopodium alpinum extract, 5-9 wt% of oat beta-glucan and 1-5 wt% of olive leaf extract.
In some embodiments, the oat β -glucan may be selected to be 5%, 6%, 7%, 8%, 9%;
the olive leaf extract can be selected from 1%, 2%, 3%, 4%, 5%;
preferably, the sum of the leontopodium alpinum extract, the oat beta-glucan and the olive leaf extract is 100%;
further, the skin care and soothing repairing composition comprises 90% of leontopodium alpinum extract, 5% of oat beta-glucan and 5% of olive leaf extract in percentage by weight.
Further, the skin care and soothing repairing composition comprises 90% of leontopodium alpinum extract, 7% of oat beta-glucan and 3% of olive leaf extract in percentage by weight.
Further, the skin care and soothing repairing composition comprises 90% of leontopodium alpinum extract, 9% of oat beta-glucan and 1% of olive leaf extract in percentage by weight.
In order to achieve the second invention purpose, the invention adopts the following technical scheme:
use of a skin care soothing rejuvenating composition as hereinbefore defined in an amount of from 1 to 2% by weight of the skin care product.
In some embodiments of the invention, the composition is added to the skin care product in an amount of 1wt%, 1.1wt%, 1.2wt%, 1.3wt%, 1.4wt%, 1.5wt%, 1.6wt%, 1.7wt%, 1.8wt%, 1.9wt%, or 2wt%.
Further, the skin care soothing and repairing composition is applied to skin care, and the skin care product comprises a product for soothing and/or repairing the acid brushed skin.
Further, the skin care product comprises emulsion, cream, spray, essence, essential oil, face cleaning cream, cosmetic water, facial mask and gel.
As a further preferred aspect of the present invention, the skin care soothing and repairing composition or the skin care product of the present invention may further comprise additives, extracts, etc. such as:
the cosmetic or composition of the present invention may comprise a cosmetically effective amount of at least one compound, oil or wax selected from cosmetic or pharmaceutical adjuvants formed from moisturizers (moisture retaining materials), moisturizers and emollients, such as, but not limited to, polyols and polyethers such as glycerol, ethylhexyl glycerol, octanediol, pentanediol, butanediol, propylene glycol and its derivatives, triethylene glycol, polyethylene glycol, glycereth-26, sorbeth-30; panthenol; pyroglutamic acid and salts or derivatives thereof; amino acids such as serine, proline, alanine, glutamic acid or arginine, etc.
The cosmetic or composition of the present invention may comprise a cosmetically effective amount of at least one agent that stimulates wound healing, auxiliary wound healing agents, re-epithelializing stimulating and/or auxiliary re-epithelializing agents selected from, for example, but not limited to, extracts of clematis, centella asiatica, musk rose, echinacea, comfrey, equisetum arvense, hypericum perforatum, mimosa, avocado, prune, aloe vera, and the like.
The cosmetic or composition of the present invention may comprise a cosmetically effective amount of at least one anti-wrinkle and/or anti-aging agent selected from, for example, but not limited to, extracts or hydrolyzed extracts of vitis vinifera, rosa canina, curcuma longa, theobroma cacao, ginkgo biloba, or dunaliella salina, etc., palmitoyl pentapeptide-4, palmitoyl tetrapeptide-7, palmitoyl oligopeptides, etc., and/or mixtures thereof.
The cosmetic or composition of the present invention may comprise a cosmetically effective amount of at least one whitening or depigmenting agent or melanin synthesis inhibitor selected from, for example, but not limited to, extracts of yarrow, aloe vera, neem, camellia, bread tree, sticktight, broussonetia papyrifera, chlorella vulgaris, cimicifuga foetida, emblic leafflower fruit, glycyrrhiza glabra, glycyrrhiza uralensis, ilex purpurea, angelicae gigantis, ligusticum chuanxiong, caput crassa, morinda officinalis, white mulberry, pseudostellaria heterophylla, rumex crispa, rumex javanica, sapindus mukorossi, scutellaria baicalensis, sedum sarmentosum, chickweed, wheat, bearberry leaf, withania, or nightshade, and the like, and/or mixtures thereof.
The cosmetic or pharmaceutical composition of the invention may comprise a cosmetically effective amount of at least one natural extract or essential oil for treating sensitive skin, selected from, for example, but not limited to, okra, amaranth, oil from the root of zizhuyu hedyotis, aloe vera, marshmallow, slender tangerine peel, miscanthus floridulus, aralia gymnema, aralia elata, poppy cirsium, arnica, wormwood, eleutheroma grandiflorum, rhododendron aurea, calendula, tea tree, tarragon, campsis grandiflora, capsicum, xanthophylla, elaeagnus mollis, coriander, chamomile germania, chrysanthemum indicum, cimicifugae racemosa, camphor tree, clematis vitifolia, dodder, crinum asiaticum, ebony rosewood, gentianella, witch hazel, claw hook, hypericum perforatum, tenuifolia, lilium angustifolia, lavender latum, holy mother, perillaseed, periwinkle, rose pepper, rose mallow-leaved pepper, and the like extracts of liquidambar styraciflua, lithospermum floribundum, majoram longifolia, malva sylvestris, sessile cornia, tea tree australis, alfalfa, yellow orchid, mimosa, marjoram, oregano, rice grain, kidney beans, phyllanthus urinaria, callicarpa fulva, pistachio, polygonum hydropiper, cherokee rose, rosemary, quercus robur, rauvolfia, castor bean, raspberry, arrowhead, salix alba, strawberry, soapberry, sesbania grandiflora, silybum marianum, pacific oblonga, shorttongue spiraea, common thyme, linden, ailanthus altissima, urtica indica, trichosanthes pentandra, uncaria, vaccinium myrtillus, acerola, resveratrol and the like, and/or mixtures thereof.
The cosmetic or composition of the present invention may comprise a cosmetically effective amount of at least one anti-itch agent selected from, for example, but not limited to, okra, oldenlandia, magnolia, extracts of plants of common alstonia, marshmallow, green tangerine peel, meadowsweet, aralia gymnadensis, aralia elata, poppy thistle, rhododendron coreana, tea tree, tarragon, campsis pachycarpa, yellow thorn, epiphyllum, chrysanthemum indicum, black cohosh, camphor tree, clematis vitifolia, dodder, ebony, gentiana scabra bunge, hamamelis, sarcandra graciliata, lavandin angustifolia, lavandula latifolia, liquidambar styracifolia, lithospermum parviflora, mazu longleaf, flaccid anemone, alfalfa, cymbidium, mimosa, rice distillers grains, phaseolus vulgaris, phyllanthus urinaria, pistachio, polygonum hydropiper, quercus, raurea, castor bean, raspberry, zizandra, sagittaria italica, rodgeria indica, sessileris, sesbania grandiflora, bassia, pacifica, athea sinensis, pterocarpus indicus, litsea blumea, litsea cubeba, a, litsea cubeba, and one or more biological or one biological sources of the plant.
The cosmetic or composition of the present invention may comprise a cosmetically effective amount of at least one anti-inflammatory and/or analgesic agent selected from, for example, but not limited to, madecassoside extract, echinacea extract, amaranth seed oil, sandalwood oil, peach leaf extract, aloe vera extract, arnica montana, wormwood, horseshoe tree, calendula, capsicum, coriander, chamomile, crinum asiaticum, witch hazel, claw grass, and the like, or mixtures thereof.
Compared with the prior art, the invention has the following beneficial effects:
firstly, the composition obtained by compounding the leontopodium alpinum extract, the oat beta-glucan and the olive leaf extract contains rich edetic acid, bioflavonoids, flavonoids, olive polyphenols, polysaccharides and the like, can maintain skin micro-ecology while increasing the generation of elastic collagen and promoting wound healing, helps to keep the natural balance of skin, inhibits the expression of inflammatory factors, reduces the sensitivity of the skin, improves the water content level of stratum corneum and increases the regeneration capacity of damaged skin cells. The damaged skin barrier is repaired while skin irritation symptoms such as epidermal chemical irritation, dryness, inflammatory reaction and the like are solved, the irritation tolerance of the skin after acid brushing is improved, and the potential risk of skin barrier damage is reduced.
Secondly, the leontopodium alpinum extract, the oat beta-glucan and the olive leaf extract which are used as raw materials of the skin care, soothing and repairing composition generate a synergistic effect after acid brushing, so that the skin care, soothing and repairing composition has a far better effect on soothing and repairing the skin after acid brushing than a composition containing only part of the raw materials or a composition prepared by matching part of the raw materials with other components.
Thirdly, the acid brushing skin care soothing and repairing composition provided by the invention has a small dosage and a remarkable effect in skin care products, and can obviously improve adverse symptoms such as increased heme content and epidermis water loss of the acid brushing skin only by accounting for 1-2wt% of the acid brushing skin care products.
Detailed Description
The technical solution of the present invention is further explained by the following embodiments. It should be understood by those skilled in the art that the examples are only for the understanding of the present invention and should not be construed as the specific limitations of the present invention. The reagents used are conventional reagents which are not indicated by manufacturers and are commercially available. Unless otherwise specified, the% and parts in the present invention are weight percentage and parts.
Used as follows:
edelweiss extract was purchased from imperial corporation;
oat beta-glucan was purchased from phyta;
olive leaf extract was purchased from hausted corporation;
yeast beta-glucan was purchased from onlida;
olive fruit oil was purchased from weisheng corporation;
porphyridium extract was purchased from Pingyan corporation;
citrus extracts were obtained from Gama Bigeleau, inc.;
the licorice extract was purchased from Panzhi corporation.
Example 1
A skin care and soothing repairing composition after acid brushing is prepared from 90g of edelweiss extract, 5g of oat beta-glucan and 5g of olive leaf extract by uniformly mixing the raw materials. This composition was designated as composition A.
Example 2
A skin care and soothing repairing composition after acid brushing comprises 90g of edelweiss extract, 9g of oat beta-glucan and 1g of olive leaf extract, and is obtained by uniformly mixing the raw materials. This composition was designated composition B.
Example 3
A skin care and soothing repairing composition after acid brushing comprises 90g of edelweiss extract, 7g of oat beta-glucan and 3g of olive leaf extract, and is obtained by uniformly mixing the raw materials. This composition was designated composition C.
Comparative example 1 preparation of composition D
Respectively and uniformly mixing 90 parts of alpine edelweiss extract and 5 parts of oat beta-glucan.
Comparative example 2 preparation of composition E
Respectively and uniformly mixing 90 parts of the alpine edelweiss extract and 10 parts of oat beta-glucan.
Comparative example 3 preparation of composition F
Respectively mixing 90 parts of edelweiss extract and 1 part of olive leaf extract uniformly.
Comparative example 4 preparation of composition G
Respectively mixing 90 parts of edelweiss extractive and 5 parts of olive leaf extractive uniformly.
Comparative example 5 preparation of composition H
Respectively and uniformly mixing 90 parts of the edelweiss extract, 5 parts of the olive leaf extract and 5 parts of yeast beta-glucan.
Comparative example 6 preparation of composition I
Respectively and uniformly mixing 90 parts of alpine edelweiss extract, 5 parts of oat beta-glucan and 5 parts of olive fruit oil.
Comparative example 7 preparation of composition J
Respectively and uniformly mixing 90 parts of edelweiss extract, 5 parts of oat beta-glucan and 5 parts of porphyridium extract.
Comparative example 8 preparation of composition K
Respectively and uniformly mixing 90 parts of alpine edelweiss extract, 5 parts of oat beta-glucan and 5 parts of citrus extract.
Comparative example 9 preparation of composition L
Respectively and uniformly mixing 90 parts of alpine edelweiss extract, 5 parts of oat beta-glucan and 5 parts of liquorice extract.
Comparative example 10 preparation of composition M
Respectively mixing 90 parts of edelweiss extract and 10 parts of olive leaf extract uniformly.
Effect test
1. Salicylic acid spur pain test
Test samples: examples 1-3, comparative examples 1-10.
The test method comprises the following steps: a2% salicylic acid solution was applied to the nasolabial sulcus of the subject by a single blinding method, and the sensation of stinging was scored according to the subject after 2.5min and 5min of application. The discomfort degree of pruritus, stabbing pain and burning pain at the tested part is evaluated by the test subject, and the evaluation is carried out according to a 4-point method (0 is no feeling, 1 is mild, 2 is moderate and 3 is severe), and the positive salicylic acid stabbing pain is judged if the sum of the stabbing pain scores is more than or equal to 3. According to the salicylic acid stinging screening result, the subjects are averagely divided into 13 groups (33 persons in each group), different test samples are respectively smeared on each group, the test samples are respectively used for 1 time in the morning and at the evening every day in the testing period, and meanwhile, the subjects are required not to use products with the same types and functions as the test samples.
The results show that: the salicylic acid sting screening value is used as a basic value, the salicylic acid sting test is carried out again 14 and 28 days after the product is used, statistical analysis is carried out on the salicylic acid sting values before and after the product is used by using SPSS, and the difference P <0.05 has statistical significance. Salicylic acid irritation score results description statistics test results are shown in table 1 below.
Table 1 salicylic acid challenge score results description statistics test results
Figure BDA0004021353130000121
Figure BDA0004021353130000131
Statistical analysis of salicylic acid challenge scores are shown in table 2.
TABLE 2 statistical analysis of salicylic acid irritation score results
Figure BDA0004021353130000132
Figure BDA0004021353130000141
And (4) analyzing results: as can be seen from the results of the experiments and statistical analyses in tables 1 and 2, examples 1 to 3 had significant effects (p < 0.001) on the skin salicylic acid prick alleviating score after 14 and 28 days of use. Comparative examples 2, 4, 6, 7, 8, 9, 10 had no significant effect (p > 0.05) on the skin sore pain relief score after 14 days of use and some significant effect (p < 0.05) on the skin sore pain relief score after 28 days of use; comparative examples 1, 3, 5 had no significant effect (p > 0.05) on the skin's salsa relief score after 14 and 28 days of use. The examples 1-3 can obviously improve the tolerance of the skin to the salicylic acid; comparative examples 2, 4, 6, 7, 8, 9, 10 had some effect on increasing the skin's tolerance to salicylic acid; comparative examples 1, 3, and 5 failed to significantly improve the skin's tolerance to salicylic acid.
2. Test experiment for relieving and repairing efficacy of induced human skin erythema model
2.1 preparation of samples
6 types of essence solutions were prepared from the composition A obtained in example 1 in different amounts as test samples, and a negative control was set without the essence solution of the composition A. The formula of each serum is shown in table 3.
Table 3 formula of essence
Figure BDA0004021353130000151
2.2 Experimental testing
Test samples: essence 1-7
The test method comprises the following steps: test area marking was performed on the inner sides of the forearms of both hands of the subjects (33 persons were recruited in total), each test area was 2cm × 2cm (7 test areas, the areas were randomly distributed on a blinded table), and skin melanin and hemoglobin test probes of Courage + Khazaka were used before the start of the experiment
Figure BDA0004021353130000152
MX18 and water loss test probe
Figure BDA0004021353130000153
TM300, measuring the skin heme content and the epidermal water loss TEWL value of the test sample area and the blank control area; after the measurement is finished, 2% salicylic acid solution patch application is carried out for 24h, after 24h, the patch tester is removed, the forearm exposure state is maintained, after the patch tester sits for 30min under constant temperature and humidity conditions, the skin heme content and the epidermis water loss TEWL value in the marked area are measured again, the product is distributed, different areas of the testee are coated with different products, and the skin heme content and the epidermis water loss TEWL value are measured again after visits D3 and D7.
The results show that: the skin heme content and the epidermis water loss TEWL value after the spot tester acts for 24 hours are taken as basic values, the product is measured again after 3 and 7 days after use, the SPSS is used for carrying out statistical analysis on the skin heme content and the epidermis water loss TEWL value before and after the product is used, and P <0.05 is the difference, so that the statistical significance is realized.
The results of skin hemoglobin content are depicted in table 4, and the results of skin hemoglobin content are analyzed in table 5.
Table 4 skin hemoglobin content results descriptive statistics
Figure BDA0004021353130000161
TABLE 5 statistical analysis of the results of skin hemoglobin content
Figure BDA0004021353130000162
Figure BDA0004021353130000171
And (3) analyzing a heme content test experiment result: the essence liquids 3, 4, 5, 6 and 7 can obviously reduce the skin heme content after being used for 3 days, the skin heme content is further reduced after being used for 7 days, p is less than 0.05 through statistical test, the significant difference exists, the score reduction amplitude is in an increasing trend along with the sequence of 3, 4 and 5, the skin heme reduction amplitude reaches the peak value in the essence liquid 5, and the effects of the essence liquids 6 and 7 are slightly reduced and are between 4 and 5; the skin hemoglobin content was not significantly reduced in groups D3 of serum 1 and 2, and the significant reduction in skin hemoglobin content in group D7 may be due to the self-healing function of the skin. By comparing the D3-D0 difference and the D7-D0 difference of the groups 2-7 of the essence with the D3-D0 difference and the D7-D0 difference of the group 1 of the essence, each group 3-7 shows good effect of reducing the content of skin heme.
The description statistics of the TEWL value results of the epidermis water loss are shown in table 6, and the statistical analysis of the TEWL value results of the epidermis water loss is shown in table 7.
Table 6 epidermal water loss TEWL value result description statistics
Figure BDA0004021353130000181
TABLE 7 statistics of TEWL values for epidermal water loss
Figure BDA0004021353130000182
Figure BDA0004021353130000191
Figure BDA0004021353130000201
Analysis of skin water loss TEWL value test experiment results: the TEWL value of the epidermis water loss can be obviously reduced after the essence 1-7 is used for 3 days and 7 days, the self-repairing function of the skin is considered, the difference value before and after each group is compared is not practical, the D3-D0 difference value and the D7-D0 difference value of the essence 2-7 groups are compared with the D3-D0 difference value and the D7-D0 difference value of the essence 1 group, the TEWL value of each group 3-7 is obviously reduced in the D3 and D7 days through statistical test, the reduction effect of the TEWL value is increased along with the sequence of 3, 4 and 5, the TEWL value reduction amplitude of the epidermis water loss in the essence 5 reaches the peak value, and the effect of the essences 6 and 7 is slightly reduced and is between 4 and 5; the 2 groups did not show significant reduction in days D3 and D7, and the comparison of 3-7 groups showed good reduction in TEWL value of epidermal water loss.
The skin heme content test experiment and the skin water loss TEWL value test experiment show that the usage amount of the skin care, relieving and repairing composition after acid brushing in the skin care product is preferably 1-2wt%, the efficacy of the product is not obvious when the usage amount is less than 1wt%, and the efficacy of the product is not obviously improved when the usage amount is more than 2wt%.
The applicant states that the process of the present invention is illustrated by the above examples, but the present invention is not limited to the above process steps, i.e. it is not meant to imply that the present invention must rely on the above process steps to be carried out. It will be apparent to those skilled in the art that any modifications to the present invention, equivalent substitutions of selected materials and additions of auxiliary components, selection of specific forms, etc., are within the scope and disclosure of the present invention.

Claims (8)

1. A skin care soothing and rejuvenating composition comprising an extract of Leontopodium alpinum, oat beta glucan, and olive leaf extract.
2. The skin care soothing repair composition as claimed in claim 1, wherein the composition comprises 90% by weight of edelweiss extract, 5-9% by weight of oat β -glucan, and 1-5% by weight of olive leaf extract.
3. The skin care soothing repair composition as claimed in claim 2, wherein the composition comprises 90% by weight of edelweiss extract, 5% by weight of oat β -glucan, 5% by weight of olive leaf extract.
4. The skin care soothing repair composition as claimed in claim 2, wherein the composition comprises 90% by weight of edelweiss extract, 7% by weight of oat β -glucan, 3% by weight of olive leaf extract.
5. The skin care soothing repair composition as claimed in claim 2, wherein the composition comprises 90% by weight of edelweiss extract, 9% by weight of oat β -glucan, 1% by weight of olive leaf extract.
6. Use of a skin care soothing rejuvenating composition as defined in any one of claims 1 to 5 wherein said composition is added to a skin care product in an amount of from 1 to 2% by weight.
7. Use of a skin care soothing repair composition according to claim 6 wherein the skin care product comprises a soothing and/or repairing post-brush skin product.
8. The use of a skin care soothing repair composition as claimed in claim 7 wherein said skin care product comprises a lotion, cream, spray, serum, essential oil, face cleanser, toner, face mask, gel.
CN202211691888.9A 2022-12-27 2022-12-27 Skin care and soothing repair composition and application thereof Pending CN115804745A (en)

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