CN115779061B

CN115779061B - Traditional Chinese medicine composition for relieving allergic rhinitis and preparation method thereof

Info

Publication number: CN115779061B
Application number: CN202211648635.3A
Authority: CN
Inventors: 翟佳丽; 赵光涛
Original assignee: Binzhou Medical College
Current assignee: Binzhou Medical College
Priority date: 2022-12-21
Filing date: 2022-12-21
Publication date: 2023-10-20
Anticipated expiration: 2042-12-21
Also published as: CN115779061A

Abstract

The invention discloses a traditional Chinese medicine composition for relieving allergic rhinitis and a preparation method thereof, and relates to the technical field of medicine preparation. The traditional Chinese medicine composition comprises the following raw materials in parts by weight: 1.5 to 2.5 parts of Chinese ephedra, 0.8 to 1.2 parts of asarum, 0.8 to 1.2 parts of prepared common monkshood mother root, 1.5 to 2.5 parts of cassia twig, 0.8 to 1.2 parts of white paeony root, 0.8 to 1.2 parts of pilose asiabell root, 1.5 to 2.5 parts of largehead atractylodes rhizome, 1.5 to 2.5 parts of Indian buead, 1.5 to 2.5 parts of dried orange peel, 0.8 to 1.2 parts of Chinese magnoliavine fruit, 0.8 to 1.2 parts of perilla fruit and 0.8 to 1.2 parts of radish seed. The traditional Chinese medicine composition can effectively relieve symptoms of nasal obstruction, nasal itching, sneeze and watery nasal discharge of patients with allergic rhinitis; and is convenient for long-term external use of patients, and can avoid the problems of increasing gastrointestinal tract burden and possibly causing liver and kidney injury caused by oral administration of medicines.

Description

Traditional Chinese medicine composition for relieving allergic rhinitis and preparation method thereof

Technical Field

The invention relates to the technical field of medicine preparation, in particular to a traditional Chinese medicine composition for relieving allergic rhinitis and a preparation method thereof.

Background

Allergic rhinitis is allergic inflammation of the nasal mucosa in the onset of allergic rhinitis, which is mediated mainly by immunoglobulin E (IgE), and is a major clinical symptom of nasal congestion, nasal itching, sneezing, runny nose, after exposure to allergens. The incidence rate of allergic rhinitis is about 10-25% in the world and has a tendency to increase year by year. At present, most allergic rhinitis patients are generally treated by western medicine antiallergic drugs at the time of attack, and most patients can lighten or control the illness state, but relapse is easy to occur after stopping the drug; and many patients clinically have relatively refractory disease conditions, and even if the patients are treated by using larger doses of medicaments, even the combined immunotherapy or surgical treatment cannot effectively control symptoms. The traditional Chinese medicine considers that the allergic rhinitis is caused by viscera dysfunction, exogenous wind-cold, invasion of pathogenic qi into nasal orifices and the like, and traditional Chinese medicines with pungent and warm natured drugs such as cassia twig, asarum and the like are adopted in treatment, or treatment methods with yang warming and cold dispelling such as infrared therapeutic equipment, moxibustion and the like are adopted. However, allergic rhinitis is a recurrent chronic disease, and patients often have difficulty adhering to long-term oral administration, and the burden on the gastrointestinal tract and the possibility of liver and kidney injury are aggravated. Therefore, the external traditional Chinese medicine composition with multiple effects of diminishing inflammation, resisting allergy and relieving stuffy nose is researched and prepared to solve the problem that allergic rhinitis needs to be solved.

Disclosure of Invention

In order to solve the technical problems, the invention aims to provide a traditional Chinese medicine composition for relieving allergic rhinitis and a preparation method thereof, so as to solve the problems that oral administration of allergic rhinitis medicines in the prior art increases gastrointestinal tract burden and may cause liver and kidney injury.

The technical scheme for solving the technical problems is as follows: the traditional Chinese medicine composition for relieving allergic rhinitis comprises the following raw materials in parts by weight: 1.5 to 2.5 parts of Chinese ephedra, 0.8 to 1.2 parts of asarum, 1.5 to 2.5 parts of cassia twig, 0.8 to 1.2 parts of prepared common monkshood mother root, 0.8 to 1.2 parts of white paeony root, 0.8 to 1.2 parts of pilose asiabell root, 1.5 to 2.5 parts of largehead atractylodes rhizome, 1.5 to 2.5 parts of Indian buead, 1.5 to 2.5 parts of dried orange peel, 0.8 to 1.2 parts of Chinese magnoliavine fruit, 0.8 to 1.2 parts of perilla fruit and 0.8 to 1.2 parts of radish seed.

The beneficial effects of the invention are as follows: the traditional Chinese medicine composition can effectively relieve symptoms of nasal obstruction, nasal itching, sneeze and watery nasal discharge of patients with allergic rhinitis; and is convenient for long-term external use of patients, and can avoid the problems of increasing gastrointestinal tract burden and possibly causing liver and kidney injury caused by oral administration of medicines.

The traditional Chinese medicine considers that the allergic rhinitis is caused by viscera dysfunction, exogenous wind-cold, invasion of pathogenic qi into nasal orifices and the like, and the traditional Chinese medicine treatment principle is that yang warming, cold dispelling, spleen strengthening, lung tonifying, wind dispelling, orifice dredging, and nasal discharge astringing.

The Chinese medicinal composition takes ephedra and asarum as principal drugs, cassia twig, white paeony root and prepared common monkshood mother root as ministerial drugs, radix codonopsis pilosulae, bighead atractylodes rhizome, poria cocos and dried orange peel as adjuvant drugs, and shizandra berry, perilla fruit and radish seed as conductant drugs. Wherein, herba Ephedrae is used as principal drug for dispelling cold and relieving exterior syndrome, and herba asari is used for warming lung and resolving fluid retention. Gui Zhi can promote menstruation, invigorate yang, relieve muscular exterior syndrome, and dispel pathogenic wind-cold; paeonia lactiflora benefits yin and astringes nutrient, radix aconiti preparata warms kidney and assists yang, and three medicines are used as ministerial medicines to assist monarch medicines, and evil and healthy energy are both considered, and nutrient and defensive energy are treated simultaneously. Radix codonopsis pilosulae, rhizoma atractylodis macrocephalae, poria cocos and dried orange peel are used as adjuvant drugs for tonifying spleen and lung, and the four are used as adjuvant drugs for tonifying spleen and qi to promote diuresis. Fructus Schisandrae astringes lung and collects nasal discharge, and is blended with fructus Perillae and Raphani semen to make the effective components of the medicine easy to be absorbed by skin, and the three are combined as the guiding drug. The Chinese medicinal composition has the effects of tonifying middle-jiao and strengthening middle-jiao, and can effectively relieve the symptoms of allergic rhinitis, thereby achieving the aim of treating both symptoms and root causes.

Based on the technical scheme, the invention can also be improved as follows:

further, the traditional Chinese medicine composition comprises the following raw materials in parts by weight: 2 parts of Chinese ephedra, 1 part of asarum, 2 parts of cassia twig, 1 part of white peony root, 1 part of radix codonopsitis, 2 parts of bighead atractylodes rhizome, 2 parts of poria cocos, 1 part of dried orange peel, 1 part of Chinese magnoliavine fruit, 1 part of perilla fruit, 1 part of radish seed and 1 part of prepared common monkshood mother root.

The invention also provides a preparation method of the traditional Chinese medicine composition for relieving allergic rhinitis, which comprises the following steps:

(1) Parching fructus Perillae and Raphani semen to grey black, respectively, and making into parched fructus Perillae and parched Raphani semen;

(2) Drying herba Ephedrae, herba asari, ramulus Cinnamomi, radix Paeoniae alba, radix Codonopsis, atractylodis rhizoma, poria, pericarpium Citri Tangerinae, fructus Schisandrae and radix Aconiti Preparata to obtain pretreated raw materials;

(3) Mixing the stir-fried perilla seeds and the stir-fried radish seeds prepared in the step (1) with the pretreatment raw materials prepared in the step (2), and then crushing and sieving to obtain traditional Chinese medicine powder;

(4) Heating ginger juice, adding medical vaseline, continuously heating to boil and bubble, then adding the traditional Chinese medicine powder prepared in the step (3), stirring, cooling, and obtaining the traditional Chinese medicine composition for relieving allergic rhinitis.

Further, in the step (1), the mixture is fried to be gray black at the temperature of 260-280 ℃.

Further, in the step (2), drying is performed at 40-60 ℃.

Further, in the step (3), sieving with a 200-300 mesh sieve.

Further, in the step (4), the mass ratio of ginger juice to medical vaseline to traditional Chinese medicine powder is 1.8-2.2:1:1.8-2.2.

Further, in the step (4), the ginger juice is prepared by the following method: crushing rhizoma Zingiberis recens, and squeezing to obtain rhizoma Zingiberis recens juice.

The invention also provides a using method of the traditional Chinese medicine composition for relieving allergic rhinitis, which comprises the following steps: the method comprises the following steps: the traditional Chinese medicine composition for relieving allergic rhinitis is smeared on gauze, is applied to the 1/3 position of the spine of the middle line of the back of a patient, is heated for 25-35min, and is taken off.

Further, before heating, both ends of the gauze were adhered to the skin with tape.

Further, the heating temperature is 35-45 ℃.

Further, the skin is heated by an infrared therapeutic apparatus or a moxibustion box, so that the medicine composition is completely softened, and the skin at the application position is flushed and moist.

The invention also provides application of the traditional Chinese medicine composition for relieving allergic rhinitis in preparation of medicines for relieving allergic rhinitis.

The invention also provides a medicine for relieving allergic rhinitis, which comprises the traditional Chinese medicine composition for relieving allergic rhinitis.

The invention has the following beneficial effects:

1. the invention selects and optimizes the traditional Chinese medicines, so that the prepared traditional Chinese medicine composition has stronger antiallergic nasal orifice dredging efficacy when being used for allergic rhinitis.

2. One of the blending liquids of the traditional Chinese medicine composition is ginger juice, and the ginger juice contains effective components such as gingerol, gingerol and the like, so that the immunity of a human body can be enhanced, a certain inhibition effect on hypersensitivity reaction is achieved, and the anti-allergic effect is stronger by the synergistic traditional Chinese medicine composition; meanwhile, the ginger juice has small irritation to human skin, and is not easy to cause skin foaming; in addition, the materials are convenient to obtain, and the method is economical and practical. The second blending liquid of the traditional Chinese medicine composition is Vaseline, and the Vaseline can keep the traditional Chinese medicine composition in a semi-solid state at room temperature, so that the traditional Chinese medicine composition is easy to store.

3. When the traditional Chinese medicine composition is prepared, the mixed liquid of vaseline and ginger juice is heated to a boiling state, and the temperature reaches more than 100 ℃, so that the added traditional Chinese medicine powder can be sterilized and disinfected, and meanwhile, the effective components of the medicine can be dissolved in a large amount; the cooled Chinese medicinal composition is semi-fluid, and vaseline can moisten and protect skin when applied to back.

4. The gauze is used as a carrier of the traditional Chinese medicine composition, and when the traditional Chinese medicine composition is applied to skin, the gauze is in closer contact with the skin, and can completely fit the back curve of the body, so that the absorption efficiency of the traditional Chinese medicine active ingredients by the skin is higher.

Drawings

FIG. 1 is a diagram of a decoction piece of the traditional Chinese medicine used in example 1;

FIG. 2 shows the powder of the Chinese medicine prepared in example 1;

FIG. 3 is a ginger used in example 1;

FIG. 4 is a ginger juice prepared in example 1;

FIG. 5 is a diagram of the medical petrolatum used in example 1;

fig. 6 shows a Chinese medicinal composition for relieving allergic rhinitis prepared in example 1.

Detailed Description

The principles and features of the present invention are described below with reference to the drawings, the examples are illustrated for the purpose of illustrating the invention and are not to be construed as limiting the scope of the invention. The specific conditions are not noted in the examples and are carried out according to conventional conditions or conditions recommended by the manufacturer. The reagents or apparatus used were conventional products commercially available without the manufacturer's attention.

Example 1:

a traditional Chinese medicine composition for relieving allergic rhinitis comprises the following raw materials in parts by weight: 2 parts of Chinese ephedra, 1 part of asarum, 2 parts of cassia twig, 1 part of white peony root, 1 part of radix codonopsitis, 2 parts of bighead atractylodes rhizome, 2 parts of poria cocos, 1 part of dried orange peel, 1 part of Chinese magnoliavine fruit, 1 part of perilla fruit, 1 part of radish seed and 1 part of prepared common monkshood mother root. (see figure 1) a Chinese medicinal composition for relieving allergic rhinitis, the preparation method comprises the following steps:

(2) Drying herba Ephedrae, herba asari, ramulus Cinnamomi, radix Paeoniae alba, radix Codonopsis, atractylodis rhizoma, poria, pericarpium Citri Tangerinae, fructus Schisandrae and radix Aconiti Preparata in a dryer to obtain pretreated raw materials;

(3) Mixing the stir-fried perilla seeds and the stir-fried radish seeds prepared in the step (1) with the pretreatment raw materials prepared in the step (2), and then putting the mixture into a powder grinding machine for grinding and sieving for 2 times to obtain traditional Chinese medicine powder; (see FIG. 2)

(4) Peeling and crushing ginger into ginger paste, extruding ginger juice to obtain ginger juice, heating in an iron container, adding medical vaseline to melt, continuously heating to boil and bubble, and adding the traditional Chinese medicine powder prepared in the step (3) to ensure that the mass ratio of the ginger juice to the medical vaseline to the traditional Chinese medicine powder is 2:1:2, stirring into thin semisolid ointment, cooling at room temperature, and obtaining the traditional Chinese medicine composition for relieving allergic rhinitis. (see FIGS. 3-6)

Example 2:

a traditional Chinese medicine composition for relieving allergic rhinitis comprises the following raw materials in parts by weight: 1.5 parts of Chinese ephedra, 0.8 part of asarum herb, 1.5 parts of cassia twig, 0.8 part of white paeony root, 0.8 part of pilose asiabell root, 1.5 parts of largehead atractylodes rhizome, 1.5 parts of Indian buead, 1.5 parts of dried orange peel, 0.8 part of Chinese magnoliavine fruit, 0.8 part of perilla fruit, 0.8 part of radish seed and 0.8 part of prepared common monkshood mother root.

A traditional Chinese medicine composition for relieving allergic rhinitis, and a preparation method thereof comprises the following steps:

(3) Mixing the stir-fried perilla seeds and the stir-fried radish seeds prepared in the step (1) with the pretreatment raw materials prepared in the step (2), and then putting the mixture into a powder grinding machine for grinding and sieving for 2 times to obtain traditional Chinese medicine powder;

(4) Crushing ginger into ginger paste, extruding ginger juice to obtain ginger juice, heating in an iron container, adding medical vaseline to melt, continuously heating to boil and bubble, and adding the traditional Chinese medicine powder prepared in the step (3) to ensure that the mass ratio of the ginger juice to the medical vaseline to the traditional Chinese medicine powder is 1.8:1:1.8, stirring into thin semisolid ointment, cooling at room temperature, and obtaining the traditional Chinese medicine composition for relieving allergic rhinitis.

Example 3:

a traditional Chinese medicine composition for relieving allergic rhinitis comprises the following raw materials in parts by weight: 2.5 parts of Chinese ephedra, 1.2 parts of asarum, 2.5 parts of cassia twig, 1.2 parts of white paeony root, 1.2 parts of dangshen, 2.5 parts of bighead atractylodes rhizome, 2.5 parts of poria cocos, 2.5 parts of dried orange peel, 1.2 parts of shizandra berry, 1.2 parts of perilla fruit, 1.2 parts of radish seed and 1.2 parts of prepared common monkshood mother root.

(4) Crushing ginger into ginger paste, extruding ginger juice to obtain ginger juice, heating in an iron container, adding medical vaseline to melt, continuously heating to boil and bubble, and adding the traditional Chinese medicine powder prepared in the step (3) to ensure that the mass ratio of the ginger juice to the medical vaseline to the traditional Chinese medicine powder is 2.2:1:2.2, stirring the mixture into thin semisolid ointment, and cooling the mixture at room temperature to obtain the traditional Chinese medicine composition for relieving allergic rhinitis.

Comparative example 1:

a traditional Chinese medicine composition for relieving allergic rhinitis comprises the following raw materials in parts by weight: the procedure of example 1 was repeated except that the medicine contained no herba Ephedrae, herba asari, and radix Aconiti Preparata.

A traditional Chinese medicine composition for relieving allergic rhinitis, and a preparation method thereof comprises the following steps: as in example 1.

Comparative example 2:

a traditional Chinese medicine composition for relieving allergic rhinitis comprises the following raw materials in parts by weight: 2 parts of Chinese ephedra, 1 part of asarum, 1 part of prepared common monkshood mother root, 2 parts of cassia twig, 1 part of white paeony root, 1 part of pilose asiabell root, 2 parts of largehead atractylodes rhizome, 2 parts of Indian buead, 1 part of tangerine peel, 1 part of Chinese magnoliavine fruit, 1 part of perilla fruit and 1 part of radish seed. (see FIG. 1)

(4) Heating rice vinegar in an iron container, adding medical glycerol for melting, continuously heating to boiling and bubbling, and then adding the traditional Chinese medicine powder prepared in the step (3) to enable the mass ratio of the rice vinegar to the medical glycerol to the traditional Chinese medicine powder to be 2:1:2, stirring into thin semisolid ointment, cooling at room temperature, and obtaining the traditional Chinese medicine composition for relieving allergic rhinitis.

Comparative example 3:

western medicine cetirizine hydrochloride.

Test examples

The Chinese medicinal compositions for relieving allergic rhinitis prepared in example 1 and comparative examples 1 to 3 were subjected to clinical randomized controlled study, and the specific method is as follows:

1. grouping of study objects

Patients with sneeze and nasal obstruction who were treated in hospital were diagnosed, and 80 patients who met the diagnosis criteria of the guideline for diagnosis and treatment of allergic rhinitis (2009 edition) and who were included in the exclusion criteria were randomly divided into 4 groups of 20 persons each.

Diagnostic reference: guideline for diagnosis and treatment of allergic rhinitis (2009 edition): more than 2 symptoms (including 2 symptoms) appear in the symptoms such as continuous sneeze, clear water-like nasal discharge, nasal obstruction, nasal itching and the like, and the symptoms can be continuously or cumulatively increased for more than 1 hour per day, and can be accompanied with eye symptoms such as eye itching, conjunctival congestion and the like. The physical sign is as follows: pale nasal mucosa, edema, nasal watery secretions.

Inclusion criteria: (1) meets the diagnosis standard of allergic rhinitis; (2) glucocorticoid drug was not used 1 week prior to treatment; (3) age 18-60 years; (4) clear consciousness and normal cognitive function;

exclusion criteria: (1) combining chronic nasosinusitis and other diseases; (2) combined asthma or other medical conditions; (3) nasal cavity operators have been in progress in recent years; (4) patients with mental disorder or those with cognitive dysfunction cannot be treated with the combination of the drugs.

2. Therapeutic method

Each group of 20 patients was treated with the combination of drugs of example 1 and comparative examples 1-3, respectively.

In the treatment of example 1 and comparative example 1-2, the prepared traditional Chinese medicine composition was applied to gauze, and then the ointment was applied to the inner side of the back backpack blade, namely, about one third of the upper part of the back governor vessel, and then the ointment was placed on the gauze by using an ignited moxibustion box, and the gauze was taken down after moxibustion for 30min, so that the medicine composition was completely softened, and the skin at the application part was flushed and moist. Once daily, 5 days per week, for two weeks.

Comparative example 3: cetirizine hydrochloride was orally administered, 10mg each time, 1 time daily for 2 weeks.

3. Observation index and standard

1. Nasal Symptom Score (TNSS): the symptoms were classified into 4 symptoms of nasal obstruction, runny nose, itching and sneezing, each of which was scored by the degree of severity, i.e., 0 for asymptomatic, 1 for mild, 2 for moderate, 3 for relatively heavy, 4 for very heavy. The cumulative score is the nasal symptom score, with higher scores indicating greater pain.

2. Quality of Life Questionnaire (RQLQ) for nasal mucositis patients: the problems are classified into 24 items of daily activities, sleep, non-nasal/ocular symptoms, practical problems, nasal symptoms, ocular symptoms and emotion 7 (wherein daily activities are classified into activities 1, 2 and 3, sleep is classified into difficulty in falling asleep, awakening at night and poor sleep at night, non-nasal/ocular symptoms are classified into insufficient energy, thirst, reduced working ability, tiredness, difficulty in concentration and headache, practical problems are classified into inconvenience caused by having to use paper towels, need to rub nose/eye and need to repeatedly blow down, nasal symptoms are classified into nasal congestion, runny nose, sneeze and nasal discharge, ocular symptoms are classified into itching, tearing, eye pain and eye swelling, emotion is classified into ease of anger or depression, each item is classified into no trouble, 1 is almost no trouble, 2 is classified into some trouble, 3 is classified into medium degree, 4 is classified into very trouble, 5 is classified into very trouble, and 6 is classified into "trouble. The sum of the scores of the dimensions is the total score.

3. Visual Analog Scale (VAS) index: the lowest score is 0, the highest score is 10, the 0 is that the nose is completely ventilated, the 10 is that the nose is not ventilated completely, and the higher the score is, the more severe the nasal obstruction symptom is.

The above scores were all scored for symptoms before, after, and after 1 month of treatment.

4. Standard of efficacy evaluation

And (5) referring to a nimodipine method self-fitting curative effect evaluation standard. Efficacy index = [ (post-treatment TNSS score-pre-treatment TNSS score)/(pre-treatment TNSS score ] ×100%). The effect is shown: the curative effect index is more than or equal to 75 percent; the method is effective: the curative effect index is more than or equal to 25 percent when the curative effect index is more than 75 percent; invalidation: the curative effect index is less than 25%.

5. Statistical analysis

Statistical analysis was performed on the recorded data using SPSS 25.0. The measurement data are expressed as mean ± standard deviation, and the count data are expressed as frequency and percentage. The measurement data is in accordance with normal distribution and adopts independent sample t test, the measurement data is in non-parametric test if the measurement data is not in accordance with normal distribution, the counting data is in chi-square test, and P is less than 0.05 as a standard for counting significant difference.

6. Results

1. Comparison of general data for the 3 groups of patients

The general data of the gender, age and disease course of each group of patients are relatively non-statistically significant (P < 0.05) and are comparable.

2. Comparison of clinical efficacy of the above 3 groups of patients

The results of the treatment effect statistics for each group of patients are shown in Table 1:

TABLE 1 effective statistics

	Number of people/person with obvious effect	Effective number of people/person	Invalid people/person	Total effective rate/%
					Example 1	6	12	2	90％
Comparative example 1	5	10	5	75％
					Comparative example 2	3	9	8	60％
Comparative example 3	5	12	3	85％

As can be seen from table 1, the effective rate of example 1 is equivalent to the effective rate of cetirizine hydrochloride, and the treatment effect is poor after the components of comparative example 1 are changed to remove the monarch drug and comparative example 2 is substituted for the components of the auxiliary materials, which proves that the nasal cavity-freeing antiallergic effect of the formulation of the invention is better, and the components have synergistic effect.

3. Specific results for the Total Nasal Symptoms Score (TNSS), nasal mucositis patient quality of life questionnaire (RQLQ), and Visual Analog Scale (VAS) index for the 3 groups of patients are shown in table 2:

table 2 scoring results before and after treatment

As can be seen from the data in table 2 above, the patient's scoring results for the three short-term and long-term metrics described above are all better than those of comparative examples 1-3 after treatment with the pharmaceutical combination of example 1, demonstrating that the therapeutic effect of the pharmaceutical combination of example 1 is better than that of comparative examples 1-3.

7. Safety evaluation

Skin stinging, skin allergic reactions or other discomforts (palpitations, dizziness, headache, insomnia, etc.) occurring during the treatment of each group of patients were recorded. In the treatment process, the 4 groups of patients do not have skin irritation reaction, skin anaphylactic reaction or other uncomfortable feeling, which proves that the traditional Chinese medicine composition for relieving allergic rhinitis prepared by the invention has higher safety.

Comparing the pharmaceutical composition in example 1 with the pharmaceutical composition in comparative examples 1-2, it was found that the components of the comparative example 1 with the monarch drug removed and the components of the comparative example 2 with the auxiliary materials replaced were changed, and the therapeutic effect of the formulation was reduced, which proves that the formulation of the invention has an interaction relationship between the medicinal materials, so that the therapeutic effect can be improved on the basis of using less medicinal materials.

The foregoing description of the preferred embodiments of the invention is not intended to limit the invention to the precise form disclosed, and any such modifications, equivalents, and alternatives falling within the spirit and scope of the invention are intended to be included within the scope of the invention.

Claims

1. The external traditional Chinese medicine composition for relieving allergic rhinitis is characterized by being prepared from the following raw material medicines in parts by weight: 1.5 to 2.5 parts of ephedra herb, 0.8 to 1.2 parts of asarum herb, 0.8 to 1.2 parts of prepared common monkshood mother root, 1.5 to 2.5 parts of cassia twig, 0.8 to 1.2 parts of white paeony root, 0.8 to 1.2 parts of pilose asiabell root, 1.5 to 2.5 parts of largehead atractylodes rhizome, 1.5 to 2.5 parts of Indian buead, 1.5 to 2.5 parts of tangerine peel, 0.8 to 1.2 parts of Chinese magnoliavine fruit, 0.8 to 1.2 parts of perilla fruit and 0.8 to 1.2 parts of radish seed.

2. The method for preparing the external-use traditional Chinese medicine composition for relieving allergic rhinitis according to claim 1, which is characterized by comprising the following steps:

(4) Heating ginger juice, adding medical vaseline, continuously heating to boil and bubble, then adding the traditional Chinese medicine powder prepared in the step (3), stirring, cooling, and obtaining the external traditional Chinese medicine composition for relieving allergic rhinitis.

3. The method for preparing a topical Chinese medicinal composition for relieving allergic rhinitis according to claim 2, wherein in step (1), the mixture is stir-fried to be gray-black at 260-280 ℃.

4. The method for preparing a topical Chinese medicinal composition for relieving allergic rhinitis according to claim 2, wherein in step (2), the composition is dried at 40-60 ℃.

5. The method for preparing a topical Chinese medicinal composition for relieving allergic rhinitis according to claim 2, wherein in step (3), the mixture is sieved with a 200-300 mesh sieve.

6. The method for preparing a topical Chinese medicinal composition for relieving allergic rhinitis according to claim 2, wherein in step (4), the mass ratio of ginger juice, medical vaseline and Chinese medicinal powder is 1.8-2.2:1:1.8-2.2.

7. The method for preparing a topical Chinese medicinal composition for relieving allergic rhinitis according to claim 2 or 6, wherein in step (4), the ginger juice is prepared by the following method: crushing rhizoma Zingiberis recens, and squeezing to obtain rhizoma Zingiberis recens juice.

8. The use of the external-use Chinese medicinal composition for relieving allergic rhinitis according to claim 1 in the preparation of external-use medicines for relieving allergic rhinitis.

9. A topical medicament for relieving allergic rhinitis, comprising the topical Chinese medicinal composition for relieving allergic rhinitis according to claim 1.