CN115671002A - Anti-wrinkle nourishing acne-removing composition and application thereof - Google Patents
Anti-wrinkle nourishing acne-removing composition and application thereof Download PDFInfo
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- CN115671002A CN115671002A CN202211471461.8A CN202211471461A CN115671002A CN 115671002 A CN115671002 A CN 115671002A CN 202211471461 A CN202211471461 A CN 202211471461A CN 115671002 A CN115671002 A CN 115671002A
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Abstract
The invention provides an anti-wrinkle nourishing acne-removing composition which comprises a rosa roxburghii extract, a terminalia faba fruit extract, phytosphingosine and rice fermentation product filtrate. The invention creatively combines and matches the four components of the rosa multiflora extract, the terminalia faba fruit extract, the phytosphingosine and the rice fermentation product filtrate for resisting wrinkles, nourishing and removing acnes, the four components supplement each other and can synergically reduce the generation of wrinkles in multiple directions through different mechanisms, the better skin barrier effect is maintained, and the effects of resisting wrinkles, nourishing and removing acnes of the product are obvious and long-acting.
Description
Technical Field
The invention belongs to the technical field of cosmetics, and relates to an anti-wrinkle nourishing acne-removing composition and application thereof, in particular to an anti-wrinkle nourishing acne-removing composition and essence milk with anti-wrinkle nourishing acne-removing effects.
Background
Skin aging is the accumulation of cellular and structural damage that occurs progressively as an individual ages, and the aging process is divided into intrinsic and extrinsic aspects. (1) The intrinsic process refers to the phenomenon that as people age, fine wrinkles and loose skin appear on the skin. The endogenous mechanisms of skin aging are very complex, and representative aging theories mainly include a free radical theory, a genetic theory, a mitochondrial DNA damage theory and the like. (2) Extrinsic processes generally refer to the effects of environmental or other forms of exposure on the skin, causing some change. Such as deeper and coarser wrinkles, molting, dry skin, age spots, etc. The exogenous factors mainly comprise ultraviolet irradiation, cigarette smoke and other bad living habits, and the existence of the exogenous factors can accelerate the natural aging process of the skin. Aging is a progressive process of functional and organic decline that occurs in all individuals over time. And the structural changes of the dermis are the main cause of skin aging. Under the combined action of endogenous and exogenous factors of skin aging, the number of fibroblasts synthesized by the skin is gradually reduced, the capacity of synthesizing collagen and elastin is reduced, the content of aminopolysaccharide in extracellular matrixes is reduced, meanwhile, proteolytic enzyme is increased, so that the degradation of collagen and extracellular matrix components is increased, the elastic fiber net in the dermis layer disappears, and the elastic fibers degrade, denature, become thin and even segment, so that the skin is loosened and wrinkles are formed.
CN110101617A discloses an anti-wrinkle whitening moisturizing anhydrous formula skin care cosmetic, which consists of the following components in percentage by mass: phase A, 35% of glycerol; 10% of butanediol; phase B, 15% of squalane; 3% of cetyl polyethylene glycol; 2.5 percent of beeswax; phase C, ginseng radix Rubri extract 15%; vitamin C8%; 5% of Terminalia faba fruit extract; 4% of a secondary split yeast fermentation product lysate; 2.0% of salicylamide phytosphingosine; vitamin E0.5%, the invention also discloses the preparation method. The beneficial effects of the invention are as follows: the polyalcohol replaces water, so that the antioxidant ingredients in the formula are not easily hydrolyzed and oxidized, the antioxidant effect is effectively achieved, the dosage form is also stabilized, and the quality guarantee period of the product is prolonged; can combine multiple effects of anti-wrinkle, skin brightening and water replenishing while moisturizing the skin; the red ginseng extract, the vitamin C and other components are added, so that the oxidation of the active components of the antioxidant is solved. The problem of absorption of effective components is increased, and the skin-specific oil squalane is supplemented without preservatives.
CN106798722A discloses an anti-aging moisturizing repair cream containing no silicone oil, which is composed of the following components in parts by weight: 1-5 parts of dog rose fruit oil, 1-5 parts of acanthus seed oil, 1-5 parts of jojoba seed oil, 1-5 parts of Indian vine yellow seed fat, 2-8 parts of plant source emulsifier, 1-4 parts of plant source auxiliary emulsifier, 55-70 parts of water, 0.05-0.15 part of Italian wintersweet flower oil, 0.15-0.3 part of frankincense oil, 0.05-0.15 part of cinnamomum camphora oil, 0.01-0.1 part of ylang oil, 0.1-0.5 part of geranium oil, 0.8-2 parts of rice fermentation product filtrate, 0.8-2 parts of lactobacillus/soybean fermentation product extract, 0.5-2 parts of royal jelly extract, 0.8-2 parts of Gentiana lutea root extract, 0.8-2 parts of algae extract, 0.15-0.5 part of sodium polyglutamate, 0.05-0.5 part of sodium hyaluronate, 1.5-5 parts of Italian wintersweet water and 2.5-5 parts of rosa damascena water. The invention also provides a preparation method of the cream. The invention has good repairing and anti-aging effects, does not contain mineral oil, essence and harmful preservative, is skin-friendly and has no toxic or side effect.
At present, along with the rapid development of economy, people have increasingly paid more attention to cosmetics with anti-wrinkle efficacy along with the increase of living pressure while improving living standard, so that the research and development of cosmetics with multiple efficacies of anti-wrinkle nourishing and acne removal are very significant.
Disclosure of Invention
Aiming at the defects of the prior art, the invention aims to provide an anti-wrinkle nourishing acne-removing composition and application thereof.
In order to achieve the purpose, the invention adopts the following technical scheme:
in a first aspect, the present invention provides an anti-wrinkle nourishing acne-removing composition comprising a rosa roxburghii extract, a terminalia faba fruit extract, phytosphingosine, and a rice fermentation product filtrate.
Cistus extracts are rich in a natural antioxidant molecule: myricetin glycoside, which is a substance capable of accelerating the renewal of surface cells, protecting collagen and collagen fibers from damage caused by ultraviolet rays, and reducing the generation of intracellular free radicals and the increase of intracellular oxidative stress caused by ultraviolet rays UVA and UVB.
The extract of Terminalia catappa fruit is extracted from Terminalia catappa fruit, and has effects of promoting SVCT-1 (sodium ion dependent vitamin C transport protein) generation, promoting hyaluronic acid synthesis, and protecting skin compactness and smoothness; promoting synthesis of syndecan I, strengthening epidermal structural support, and resisting skin aging; promoting synthesis of procollagen I, strengthening dermis structure, and keeping skin elasticity.
The phytosphingosine is similar to skin lipid, can promote skin ceramide generation, stimulate differentiation of human epidermal keratinocytes, is an important component for water retention and barrier function, and can relieve skin irritation, resist bacteria and diminish inflammation.
The rice fermentation product filtrate is rich in various active ingredients, such as glucoside ceramide, amino acid, polysaccharide, peptide and other active factors, and has various effects of enhancing the activity of filaggrin degrading enzyme, improving the skin moisture, strengthening the skin barrier function, promoting the activity of fibroblasts, promoting the synthesis of collagen in the fibroblasts, repairing rough skin, fading fine lines of dry lines and the like.
The skin wrinkles are the phenomenon of skin relaxation caused by the decrease of fiber cells, the decrease of collagen and elastin and the increase of degradation and denaturation of elastic fibers in the dermis layer under the influence of various factors. Thus, increasing fibroblast activity, promoting collagen formation, reducing collagen degradation, maintaining cellular moisture, maintaining the skin barrier, etc., may reduce the production of skin wrinkles. In addition, the antibacterial and antioxidant capacity of the skin is improved, and the skin barrier is enhanced, so that the generation of skin acne can be reduced.
The four components are creatively combined and matched for resisting wrinkles, nourishing and removing acnes, the four components supplement each other, the synergy can be realized, the components respectively reduce the generation of wrinkles in multiple directions through different mechanisms, the better skin barrier effect is maintained, and the effects of resisting wrinkles, nourishing and removing acnes of the product are obvious and long-acting.
Preferably, the anti-wrinkle nourishing acne-removing composition comprises, by mass, 0.1-1.5 parts of a rosa roxburghii extract, 0.1-1 part of a terminalia faba fruit extract, 0.02-0.5 part of phytosphingosine and 0.5-3 parts of a rice fermentation product filtrate.
The mass parts of the rosa serrulata extract can be 0.1 part, 0.3 part, 0.5 part, 0.7 part, 0.9 part, 1.1 part, 1.3 parts, 1.5 parts and the like.
The parts by weight of the terminalia faba fruit extract can be 0.1 part, 0.3 part, 0.5 part, 0.7 part, 0.9 part, 1 part and the like.
The phytosphingosine can be 0.02 part, 0.06 part, 0.1 part, 0.2 part, 0.3 part, 0.4 part, 0.5 part and the like in parts by mass.
The weight portion of the rice fermentation product filtrate can be 0.5 portion, 0.9 portion, 1.3 portions, 1.7 portions, 2.1 portions, 2.5 portions, 2.9 portions, 3 portions and the like.
Other specific values within the above ranges can be selected, and are not described in detail herein.
Preferably, the cistus incarnata extract comprises cistus incarnata extract.
When the rosa multiflora extract comprises the rosa canina extract, the anti-wrinkle nourishing acne-removing composition has stronger anti-wrinkle nourishing effect.
In a second aspect, the invention provides the use of the anti-wrinkle nourishing acne-removing composition according to the first aspect in the preparation of cosmetics.
Preferably, the cosmetic comprises essence, essence milk, cream, mask, eye cream and facial cleanser.
The anti-wrinkle nourishing acne-removing composition can be used as a preparation raw material of cosmetics to increase the anti-wrinkle nourishing acne-removing effect of the cosmetics, wherein the cosmetics can be selected from cosmetics of any dosage form, such as essence, essence milk, cream, facial mask, eye cream, facial cleanser and the like.
In a third aspect, the invention provides an essence milk with anti-wrinkle, nourishing and acne-removing effects, and the raw materials of the essence milk with anti-wrinkle, nourishing and acne-removing effects comprise the anti-wrinkle, nourishing and acne-removing composition, oil, water and an emulsifier according to the first aspect.
The invention provides an essence milk with anti-wrinkle, nourishing and anti-acne effects, which is prepared from the raw materials of the essence milk with anti-wrinkle, nourishing and anti-acne effects of the first aspect, and has remarkable anti-wrinkle, moisturizing and anti-acne effects.
Preferably, the raw materials for preparing the essence milk with the effects of resisting wrinkles, nourishing and removing acnes further include any one or a combination of at least two of a humectant, a thickener, a pH regulator, a chelating agent and an antioxidant, the combination of at least two of the humectants, the thickener, the pH regulator, the thickener and the chelating agent, and the like, and any other combination mode can be selected, which is not described in detail herein.
Preferably, the oil comprises any one of propylene glycol dipelargonate, squalane, C13-16 isoparaffin, diisopropyl adipate, isodecyl neopentanoate or cetyl lactate or a combination of at least two of the propylene glycol dipelargonate and squalane, squalane and C13-16 isoparaffin or propylene glycol dipelargonate and C13-16 isoparaffin, and the like, wherein any combination can be selected, and the description is omitted.
More preferably, the oil comprises squalane.
The oil comprises squalane, the squalane is hydrocarbon oil prepared by hydrogenating squalene extracted from deep-sea shark liver, so the squalane is also named deep-sea shark liver oil, has strong chemical stability and high skin affinity, has good effects of maintaining skin oil balance, inhibiting cell lipid oxidation and promoting damaged cell repair, can be matched and combined with phytosphingosine in the anti-wrinkle nourishing acne-removing composition, and has stronger synergistic effects on conditioning skin oil balance and removing acne.
Preferably, the emulsifier comprises one or a combination of at least two of polysorbate-20, glyceryl stearate SE, sorbitan stearate, steareth-21 or methyl glucose sesquistearate, wherein the combination of at least two of polysorbate-20 and glyceryl stearate SE, glyceryl stearate SE and sorbitan stearate SE, or sorbitan stearate and steareth-21, and the like, and any combination can be selected, which is not described in detail herein.
More preferably, the emulsifier comprises polysorbate-20.
Preferably, the moisturizer comprises any one or combination of at least two of methyl gluceth-10, glycerol, propylene glycol, lactic acid, arginine, sodium hyaluronate or 1, 2-hexanediol, and the combination of at least two of the methyl gluceth-10 and the glycerol, the glycerol and the propylene glycol or the propylene glycol and the sodium hyaluronate, and the like, and any other combination can be selected, which is not described in detail herein.
More preferably, the moisturizer comprises a combination of glycerin and sodium hyaluronate.
The moisturizer comprises the combination of glycerin and sodium hyaluronate, wherein the glycerin and the sodium hyaluronate can be matched with the rosa roxburghii extract, the terminalia faba fruit extract, phytosphingosine and rice fermentation product filtrate, so that the synergic effect is achieved, and the essence milk containing the six components has stronger effects of resisting wrinkles, nourishing and moisturizing.
Preferably, the thickener comprises any one or a combination of at least two of acrylic acid (ester)/C10-30 alkanol acrylate cross-linked polymer, PEG-120 methyl glucose dioleate or sodium polyacrylate, the combination of at least two of acrylic acid (ester)/C10-30 alkanol acrylate cross-linked polymer and PEG-120 methyl glucose dioleate, the combination of PEG-120 methyl glucose dioleate and sodium polyacrylate or the combination of acrylic acid (ester)/C10-30 alkanol acrylate cross-linked polymer and sodium polyacrylate, and the like, and any combination mode can be selected, so that the detailed description is omitted.
Preferably, raw materials for preparing the essence milk with the effects of resisting wrinkles, nourishing and removing acnes comprise, by mass, 0.1-10 parts of the composition for resisting wrinkles, nourishing and removing acnes as described in the first aspect, 1-10 parts of oil and fat, 50-100 parts of water and 0.03-0.3 part of an emulsifier.
The anti-wrinkle nourishing acne-removing composition according to the first aspect may be, by mass, 0.1 part, 0.3 part, 0.5 part, 0.8 part, 1 part, 2 parts, 3 parts, 4 parts, 5 parts, 6 parts, 7 parts, 8 parts, 9 parts, 10 parts and the like.
The mass portion of the grease can be 1 portion, 2 portions, 3 portions, 4 portions, 5 portions, 6 portions, 7 portions, 8 portions, 9 portions, 10 portions and the like.
The water may be present in an amount of 50 parts, 55 parts, 60 parts, 65 parts, 70 parts, 75 parts, 80 parts, 85 parts, 90 parts, 95 parts, 100 parts, etc.
The emulsifier may be 0.03 parts, 0.08 parts, 0.13 parts, 0.18 parts, 0.23 parts, 0.28 parts, 0.3 parts, etc.
Other specific point values within the above numerical ranges can be selected, and are not described in detail herein.
Preferably, the raw materials for preparing the essence milk with the effects of resisting wrinkles, nourishing and removing acnes further comprise any one or a combination of at least two of 10-30 parts of a humectant, 0.1-1 part of a thickener, 0.1-1 part of a pH regulator, 0.01-0.1 part of a chelating agent or 0.1-1 part of an antioxidant in parts by mass.
The humectant can be 10 parts, 13 parts, 16 parts, 19 parts, 22 parts, 25 parts, 28 parts, 30 parts and the like by mass.
The thickener can be 0.1 part, 0.2 part, 0.3 part, 0.4 part, 0.5 part, 0.6 part, 0.7 part, 0.8 part, 0.9 part, 1 part and the like in parts by mass.
The pH regulator can be 0.1 part, 0.2 part, 0.3 part, 0.4 part, 0.5 part, 0.6 part, 0.7 part, 0.8 part, 0.9 part, 1 part and the like in parts by mass.
The chelating agent may be 0.01 parts, 0.02 parts, 0.03 parts, 0.04 parts, 0.05 parts, 0.06 parts, 0.07 parts, 0.08 parts, 0.09 parts, 0.1 parts, etc.
The antioxidant may be present in an amount of 0.1 parts, 0.2 parts, 0.3 parts, 0.4 parts, 0.5 parts, 0.6 parts, 0.7 parts, 0.8 parts, 0.9 parts, 1 part, etc.
Other specific point values within the above numerical ranges can be selected, and are not described in detail herein.
In a fourth aspect, the invention provides a preparation method of the essence milk with the effects of resisting wrinkles, nourishing and removing acnes, which comprises the following steps:
(1) Mixing water with emulsifier to obtain water phase;
(2) Mixing the aqueous phase in the step (1) with grease, stirring and homogenizing to prepare emulsion base liquid;
(3) And (3) mixing the emulsion base solution in the step (2) with the anti-wrinkle nourishing acne-removing composition in the first aspect to obtain the essence emulsion with the effects of resisting wrinkles, nourishing acne-removing.
The preparation method of the essence milk with the anti-wrinkle nourishing acne-removing effects comprises the steps of adding the anti-wrinkle nourishing acne-removing composition after preparing the emulsion base liquid, and mixing to obtain the essence milk with the anti-wrinkle nourishing acne-removing effects.
Preferably, the aqueous phase further includes any one or a combination of at least two of a humectant, a thickener, a chelating agent or an antioxidant, the combination of at least two includes a combination of a humectant and a thickener, a combination of a thickener and a chelating agent, or a combination of a chelating agent and an antioxidant, and the like, and any other combination mode can be selected, which is not described herein again.
Preferably, the temperature during the mixing in step (1) is 60-90 ℃.
The specific value of 60-90 deg.C can be selected from 60 deg.C, 65 deg.C, 70 deg.C, 75 deg.C, 80 deg.C, 85 deg.C or 90 deg.C, etc., and other specific values in the above numerical range can be selected, which is not described in detail herein.
Preferably, the rotation speed of stirring homogenization in the step (2) is 400-2500rpm.
Specific values in 400-2500rpm can be selected from 400rpm, 800rpm, 1200rpm, 1600rpm, 2000rpm, 2400rpm or 2500rpm, and other specific values in the above numerical ranges can be selected, and are not repeated herein.
Compared with the prior art, the invention has the following beneficial effects:
1. the invention creatively combines and matches the four components of the rosa multiflora extract, the terminalia fabacearum fruit extract, the phytosphingosine and the rice fermentation product filtrate for resisting wrinkles, nourishing and removing acnes, the four components supplement each other and can synergize, the components respectively reduce the generation of wrinkles in multiple directions through different mechanisms, a better skin barrier effect is maintained, and the effects of resisting wrinkles, nourishing and removing acnes of the product are obvious and long-acting.
2. The anti-wrinkle nourishing acne-removing composition can be used as a preparation raw material of cosmetics to increase the anti-wrinkle, nourishing and acne-removing effects of the cosmetics, wherein the cosmetics can be selected from cosmetics of any dosage form, such as essence, essence milk, cream, facial mask, eye cream, facial cleanser and the like.
3. The invention provides an essence milk with anti-wrinkle, nourishing and anti-acne effects, which is prepared from the raw materials of the essence milk with anti-wrinkle, nourishing and anti-acne effects of the first aspect, and has remarkable anti-wrinkle, moisturizing and anti-acne effects.
4. The preparation method of the essence milk with the anti-wrinkle nourishing acne-removing effects comprises the steps of adding the anti-wrinkle nourishing acne-removing composition after preparing the emulsion base liquid, and mixing to obtain the essence milk with the anti-wrinkle nourishing acne-removing effects.
Detailed Description
The technical solution of the present invention is further described below by way of specific embodiments. It should be understood by those skilled in the art that the examples are only for the understanding of the present invention and should not be construed as the specific limitations of the present invention.
The procedures, conditions, reagents, experimental methods and the like for carrying out the present invention are general knowledge and common general knowledge in the art except for the contents specifically mentioned below, and the present invention is not particularly limited. The experimental procedures in each example, in which specific conditions are not specified, are generally carried out under conventional conditions or under conditions recommended by the manufacturer.
Unless otherwise defined, all technical and scientific terms used herein have the same meaning as commonly understood by one of ordinary skill in the art to which this invention belongs. In case of conflict, the present specification, including definitions, will control.
Examples, comparative examples, application examples, and application comparative examples the Rosa canina extract was obtained from Irish Corp. Type, the Terminalia farinosa fruit extract was obtained from Ying and SUPEROX-CTM AF, the phytosphingosine was obtained from Natural Corp. Type, the rice fermentation product filtrate was obtained from TECHNOLONG, guangzhou, china Natural Biotechnology Co., ltd TM LADY' S SAKE LEES, water/lactic acid/arginine is available from basf as AH-Care TM L-65 product, C13-16 isoparaffin commercially available from Wako pure Inc. under the Neossance TM Squalane CN; neossance TM Hemisqualane CN, acrylic/C10-30 alkanol acrylate crosspolymer available from Megaku corporation under the model number PEMULEN TM TR-2POLYMER, polysorbate-20 is a product from Bisheng corporation of SP TWEEN 20 MBAL-LQ- (SG), congo red elastin is a product from Shanghai North Nuo Biotech limited having the elastin-Congo red E0502-5G, and elastase is a product from Mecanne having the elastase number E6156-200 mg.
Example 1
The embodiment provides an anti-wrinkle nourishing acne-removing composition which comprises the following components in parts by weight: 0.5 part of hoary rosebush root extract, 1 part of terminalia fabacer fruit extract, 0.1 part of plant sphingosine and 1.5 parts of rice fermentation product filtrate, and mixing the components to prepare the anti-wrinkle nourishing acne-removing composition.
Example 2
The embodiment provides an anti-wrinkle nourishing acne-removing composition which comprises the following components in parts by weight: 0.1 part of hoary rockrose extract, 0.8 part of terminalia root fruit extract, 0.02 part of plant sphingosine and 3 parts of rice fermentation product filtrate, and mixing the components to obtain the anti-wrinkle nourishing acne-removing composition.
Example 3
The embodiment provides an anti-wrinkle nourishing acne-removing composition which comprises the following components in parts by weight: 1.5 parts of an extract of rosa hoary, 0.1 part of an extract of terminalia faba fruit, 0.5 part of plant sphingosine and 0.5 part of a rice fermentation product filtrate, and mixing the components to prepare the anti-wrinkle nourishing acne-removing composition.
Comparative example 1
This comparative example provides an anti-wrinkle nourishing acne-removing composition which differs from example 1 only in that it does not contain rosa canina extract and the mass parts of rosa canina extract are apportioned to the terminalia faba fruit extract, phytosphingosine and rice fermentation product filtrate, the remainder being the same as example 1.
Comparative example 2
This comparative example provides an anti-wrinkle nourishing acne-removing composition, which differs from example 1 only in that the terminalia faba fruit extract is not contained and is apportioned in parts by mass to the rosa canina extract, phytosphingosine and rice fermentation product filtrate, and the rest is the same as example 1.
Comparative example 3
This comparative example provides an anti-wrinkle nourishing acne-removing composition which differs from example 1 only in that phytosphingosine is not contained and the parts by mass of phytosphingosine are apportioned to the rosa canina extract, the terminalia faba fruit extract and the rice fermentation product filtrate, the rest being the same as in example 1.
Comparative example 4
This comparative example provides an anti-wrinkle nourishing acne-removing composition which differs from example 1 only in that there is no rice fermentation product filtrate, and the parts by mass of the rice fermentation product filtrate are distributed proportionally to the rosa canina extract, the terminalia faba fruit extract and phytosphingosine, the rest being the same as example 1.
Comparative example 5
This comparative example provides a single ingredient which differs from example 1 only in that it does not contain the Rosa canina extract, the Terminalia Falcana fruit extract and phytosphingosine, and only contains the rice fermentation product filtrate, the remainder being the same as in example 1.
Comparative example 6
This comparative example provides a single ingredient which differs from example 1 only in that it does not contain the rice fermentation product filtrate, the terminalia faba fruit extract and phytosphingosine, and only contains the rosa grisea extract, the remainder being the same as example 1.
Comparative example 7
This comparative example provides a single ingredient which differs from example 1 only in that it does not contain the rice fermentation product filtrate, the rosa canina extract and phytosphingosine, and only the terminalia faba fruit extract, the remainder being the same as in example 1.
Comparative example 8
This comparative example provides a single ingredient which differs from example 1 only in the absence of the rice fermentation product filtrate, the rose-alba extract and the terminalia faba fruit extract, and the phytosphingosine only, the remainder being the same as in example 1.
Application example 1
The application example provides essence milk with the effects of resisting wrinkles, nourishing and removing acnes, and the preparation method comprises the following steps: (1) preparation raw materials of the essence milk were prepared as shown in Table 1.
TABLE 1
(2) Uniformly mixing an emulsifier, a humectant, an antioxidant, a thickener and a chelating agent according to the mass parts in the table, adding water to supplement 90 parts, adding into an emulsifying pot, setting the temperature to be 80 ℃, keeping the temperature for 20-30min, confirming that the heat preservation is stopped after the thickener swells, placing into a homogenizer, setting the rotating speed to be 1000rpm, and homogenizing for 1min.
(3) And (2) putting 5.9 parts of grease into an oil pan, heating to 60 ℃, completely dissolving the grease, adding the grease into the homogenizer in the step (2), setting the rotating speed to be 2000rpm, continuing homogenizing for 2min, then cooling to 40 ℃, adding a pH regulator (1 part by weight of water and the pH regulator) dissolved in water in advance and the anti-wrinkle nourishing acne-removing composition prepared in the embodiment 1, adjusting the rotating speed to be 500rpm, and homogenizing for 10min to prepare the essence emulsion with the anti-wrinkle nourishing acne-removing effect.
Application examples 2 to 3
The application example provides essence milk with the effects of resisting wrinkles, nourishing and removing acnes, the preparation method of the essence milk is only different from that of the application example 1 in that the composition for resisting wrinkles, nourishing and removing acnes prepared in the example 1 is replaced by the composition for resisting wrinkles, nourishing and removing acnes prepared in the examples 2 to 3, and the balance is consistent with that of the application example 1.
Application example 4
The application example provides the essence milk with the effects of resisting wrinkles, nourishing and removing acnes, and the preparation method of the essence milk is different from the application example 1 only in that glycerin and sodium hyaluronate are not contained, the glycerin and the sodium hyaluronate are proportionally distributed to four components in the composition for resisting wrinkles, nourishing and removing acnes prepared in the embodiment 1, and the balance is consistent with the application example 1.
Application example 5
The application example provides the essence milk with the effects of resisting wrinkles, nourishing and removing acnes, and the preparation method of the essence milk is only different from the application example 1 in that the essence milk does not contain squalane, the mass parts of squalane are distributed to phytosphingosine, and the balance is consistent with the application example 1.
Application of comparative examples 1 to 8
The application comparative example provides the essence milk with the effects of resisting wrinkles, nourishing and removing acnes, and the preparation method of the essence milk is only different from that of the application example 1 in that the composition for resisting wrinkles, nourishing and removing acnes prepared in the example 1 is replaced by the products for resisting wrinkles, nourishing and removing acnes prepared in the comparative examples 1-8, and the balance is consistent with that of the application example 1.
Comparative application example 9
The application comparative example provides the essence milk with the effects of resisting wrinkles, nourishing and removing acnes, and the preparation method of the essence milk is different from that of the application example 1 only in that the essence milk does not contain the composition for resisting wrinkles, nourishing and removing acnes prepared in the example 1, the composition for resisting wrinkles, nourishing and removing acnes prepared in the example 1 is proportionally distributed into glycerol and sodium hyaluronate according to the mass parts, and the balance is consistent with that of the application example 1.
Comparative application example 10
The application comparative example provides the essence milk with the effects of resisting wrinkles, nourishing and removing acnes, and the preparation method of the essence milk is only different from the application example 1 in that phytosphingosine is not contained, the phytosphingosine is distributed to squalane in parts by weight, and the balance is consistent with the application example 1.
Test example 1
The anti-acne effect evaluation is carried out on the essential milk with the functions of resisting wrinkles, nourishing and removing acnes prepared in application examples 1-3 and 5 and the application comparative example 10, and the specific evaluation method is as follows: (1) 50 volunteers with mild/moderate acne skin, with pigmentation, persistent erythema or depressed scarring between the ages of 18 and 45 were selected to maintain regular life during use. Volunteers were randomly divided into 5 groups of 10 persons each. (2) The face was divided into two, the left side was the test area and the right side was the comparison area, the left side was the test sample and the right side was wiped with clear water for 14 consecutive days. (3) And calculating a total score by using the evaluation items and the corresponding scores in the table 2 after 14 days, evaluating the acne removing effect, wherein the acne removing effect is the score of the acne removing effect on the left side of the face-the score of the acne removing effect on the right side of the face, and calculating the average value of each group.
TABLE 2
TABLE 3
| Group of | Acne treatment efficacy performance score |
| Application example 1 | 11.3 |
| Application example 2 | 11.6 |
| Application example 3 | 11.2 |
| Application example 5 | 8.9 |
| Comparative application example 10 | 7.3 |
As can be seen from the data in the table 3, the raw materials prepared in the application example 5 and the application comparative example 10 do not contain squalane and phytosphingosine respectively, and the evaluation on the acne-removing effect performance of the raw materials is lower than that of the raw materials prepared in the application example 1, which shows that the combination of squalane and phytosphingosine has a synergistic effect, and the prepared essence milk has a more remarkable acne-removing effect.
Test example 2
The anti-wrinkle effect evaluation method of the essential milk with the functions of resisting wrinkles, nourishing and removing acnes, which is prepared by the application example and the application comparative example, comprises the following specific evaluation methods: (1) The essence milk with the effects of resisting wrinkles, nourishing and removing acnes, which is prepared in the application example or the application comparative example, is diluted by adding 0.2M borate buffer solution to prepare a sample solution with the mass fraction of 15%, and the blank control group is 0.2M borate buffer solution with the equal mass without the essence milk. (2) Adding 20mg Congo red elastin into 5mL of 0.2M borate buffer solution, treating in water bath at 37 ℃ for 20min, adding 2mL of each sample solution, shaking each sample solution in water bath at 37 ℃ for 10min at constant temperature, and measuring the light absorption value A at 495 nm. (3) Adding 2mL of elastase solution of 2mg/mL, continuing to shake for 20min at constant temperature, centrifuging to obtain ase:Sub>A supernatant, measuring an absorbance value B at 495nm, and calculating the elastase inhibition rate, wherein the elastase inhibition rate is = (1- (absorbance value B-A of each sample group)/(absorbance value B-A of ase:Sub>A blank control group)). Times.100%.
TABLE 4
As can be seen from the data in Table 4, the anti-wrinkle nourishing acne-removing compositions used in the application comparative examples 1-8 are respectively from the application comparative examples 1-8, and the inhibition ratios of the corresponding elastase are lower than that of the application example 1, which shows that the four components of the rosa multiflora extract, the terminalia faba fruit extract, the phytosphingosine and the rice fermentation product filtrate are matched and applied, so that the synergistic effect can be achieved, and the anti-wrinkle effect is stronger.
Test example 3
The moisturizing effect of the essential milk with the functions of resisting wrinkles, nourishing and removing acnes prepared by the application examples and the application comparative examples is evaluated, and the specific evaluation method comprises the following steps: (1) Taking 2 parts and 5g of the anti-wrinkle, nourishing and acne-removing essence milk prepared in each application example or application comparative example, placing the sample in a weighing bottle with the diameter of 4cm, placing 2 parts and 5g of the sample in an environment with the relative humidity of 43% and 75% and the same temperature respectively, placing for 8h, recording the mass change, and calculating the average value of the moisture absorption rate of the two samples. Moisture absorption rate = (mass-5 g after 8 hours of sample)/5 g × 100%.
TABLE 5
As can be seen from the data in table 5, the anti-wrinkle nourishing acne-removing composition prepared in example 1, which does not contain glycerin and sodium hyaluronate in the preparation raw materials of application example 4 and application comparative example 9, has a lower moisture absorption rate at 43% and 75% relative humidity than that of application example 1, and shows that two components of glycerin and sodium hyaluronate can be used in combination with the four components of the anti-wrinkle nourishing acne-removing composition prepared in example 1, so that the two components have a synergistic effect and a stronger moisturizing effect. The anti-wrinkle nourishing acne-removing compositions used in the application comparative examples 1-8 are respectively from the application comparative examples 1-8, and the corresponding moisture absorption rates are lower than those of the application example 1, which shows that the four components of the rosa multiflora extract, the terminalia fabacearum fruit extract, the phytosphingosine and the rice fermentation product filtrate can be combined and matched, so that the synergistic effect is achieved, and the moisturizing effect is stronger.
Test example 4
Safety tests are carried out on the essential milk with the functions of resisting wrinkles, nourishing and removing acnes, which is prepared by the application examples and the application comparative examples. The specific method comprises the following steps: placing the essence emulsion into a spot tester with the dosage of about 0.020-0.025g, applying the spot tester with the tested substance on the bent side of the forearm of the tested person with a non-irritating adhesive tape, and lightly pressing with palm to uniformly apply the essence emulsion on the skin for 24h. And (5) removing the tested spot tester for 30min, and observing skin reaction after the indentation disappears. If the result is negative, the test is observed once more at 24h and 48h after the patch test.
Evaluation criteria: level 0: negative reaction; level 1: suspicious reactions, only faint erythema; and 2, stage: weak positive reaction, erythema, infiltration, edema, and possibly pimple; and 3, level: strong positive reaction, erythema, infiltration, edema, pimple and reaction beyond the tested area; and 4, stage 4: very strong positive reaction, obvious erythema, severe infiltration, edema, herpes fusiformis and reaction beyond the tested area.
The results show that the skin reactions of the subjects are negative, which indicates that the composition and the essence milk provided by the invention are uniform in temperature, safe and non-irritant.
The applicant states that the invention is illustrated by the above examples, but the invention is not limited to the above examples, i.e. it is not meant to be dependent on the above examples to practice the invention. It should be understood by those skilled in the art that any modifications of the present invention, equivalent substitutions of the raw materials of the product of the present invention, and the addition of auxiliary components, selection of specific modes, etc., are within the scope and disclosure of the present invention.
The preferred embodiments of the present invention have been described in detail, however, the present invention is not limited to the specific details of the above embodiments, and various simple modifications may be made to the technical solution of the present invention within the technical idea of the present invention, and these simple modifications are all within the protection scope of the present invention.
It should be noted that the various technical features described in the above embodiments can be combined in any suitable manner without contradiction, and the invention is not described in any way for the possible combinations in order to avoid unnecessary repetition.
Claims (10)
1. An anti-wrinkle nourishing acne-removing composition is characterized by comprising a rosa roxburghii extract, a terminalia faba fruit extract, phytosphingosine and rice fermentation product filtrate.
2. The anti-wrinkle nourishing acne-removing composition as claimed in claim 1, wherein the anti-wrinkle nourishing acne-removing composition comprises 0.1-1.5 parts by mass of Rosa rockii extract, 0.1-1 parts by mass of Terminalia catappa fruit extract, 0.02-0.5 parts by mass of phytosphingosine and 0.5-3 parts by mass of rice fermentation product filtrate.
3. The anti-wrinkle nourishing acne-removing composition according to claim 1 or 2, wherein the rosa serrulata extract comprises rosa canina extract.
4. Use of the anti-wrinkle nourishing acne-removing composition as defined in any one of claims 1 to 3 in the preparation of cosmetics.
5. The use according to claim 4, wherein the cosmetic comprises a serum, a cream, a mask, an eye cream, a facial cleanser.
6. An essence milk with the effects of resisting wrinkles, nourishing and removing acnes, which is characterized in that raw materials for preparing the essence milk with the effects of resisting wrinkles, nourishing and removing acnes comprise the composition for resisting wrinkles, nourishing and removing acnes as claimed in any one of claims 1 to 3, grease, water and an emulsifier.
7. The essence milk with the effects of resisting wrinkles, nourishing and removing acnes as claimed in claim 6, wherein the raw materials for preparing the essence milk with the effects of resisting wrinkles, nourishing and removing acnes further comprise any one or a combination of at least two of a humectant, a thickener, a pH regulator, a chelating agent or an antioxidant;
preferably, the grease comprises any one of propylene glycol dipelargonate, squalane, C13-16 isoparaffin, diisopropyl adipate, isodecyl neopentanoate or cetyl lactate or a combination of at least two of the same; more preferably, the oil or fat comprises squalane;
preferably, the emulsifier comprises any one or a combination of at least two of polysorbate-20, glyceryl stearate SE, sorbitan stearate, steareth-21 or methylglucose sesquistearate; more preferably, the emulsifier comprises polysorbate-20;
preferably, the moisturizer comprises any one of methyl gluceth-10, glycerin, propylene glycol, lactic acid, arginine, sodium hyaluronate, or 1, 2-hexanediol, or a combination of at least two thereof; more preferably, the moisturizer comprises a combination of glycerin and sodium hyaluronate;
preferably, the thickener comprises any one or a combination of at least two of acrylic acid/C10-30 alkanol acrylate crosspolymer, PEG-120 methyl glucose dioleate or sodium polyacrylate.
8. The essence cream with the effects of resisting wrinkles, nourishing and removing acnes as claimed in claim 6 or 7, wherein the raw materials for preparing the essence cream with the effects of resisting wrinkles, nourishing and removing acnes comprise, by mass, 0.1-10 parts of the wrinkle-resisting, nourishing and removing acnes composition as claimed in any one of claims 1-3, 1-10 parts of grease, 50-100 parts of water and 0.03-0.3 part of an emulsifier;
preferably, the raw materials for preparing the essence milk with the effects of resisting wrinkles, nourishing and removing acnes further comprise any one or a combination of at least two of 10-30 parts of a humectant, 0.1-1 part of a thickener, 0.1-1 part of a pH regulator, 0.01-0.1 part of a chelating agent or 0.1-1 part of an antioxidant in parts by mass.
9. The preparation method of the essence milk with anti-wrinkle nourishing acne-removing efficacy according to any one of claims 6 to 8, characterized by comprising the following steps:
(1) Mixing water with emulsifier to obtain water phase;
(2) Mixing the aqueous phase in the step (1) with grease, stirring and homogenizing to prepare emulsion base liquid;
(3) Mixing the emulsion base solution in the step (2) with the anti-wrinkle nourishing acne-removing composition as defined in any one of claims 1-3 to prepare the essence emulsion with the anti-wrinkle nourishing acne-removing efficacy.
10. The method for preparing the essence cream with the effects of resisting wrinkles, nourishing and removing acnes as claimed in claim 9, wherein the water phase further comprises any one or a combination of at least two of a humectant, a thickener, a chelating agent or an antioxidant;
preferably, the temperature of the mixing in the step (1) is 60-90 ℃;
preferably, the rotation speed of the stirring and homogenizing in the step (2) is 400-2500rpm.
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| US20070166275A1 (en) * | 2006-01-19 | 2007-07-19 | Mary Kay Inc. | Compositions comprising kakadu plum extract or acai berry extract |
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| CN107929152A (en) * | 2017-12-25 | 2018-04-20 | 广州智媛生物科技有限公司 | Cosmetic composition of sun-proof reparation and preparation method thereof |
| CN108578324A (en) * | 2018-07-02 | 2018-09-28 | 上海新高姿化妆品有限公司 | A kind of skin cream and preparation method thereof with long-acting moisture-keeping efficacy |
| WO2020128223A1 (en) * | 2018-12-21 | 2020-06-25 | Basf Beauty Care Solutions France Sas | Novel cosmetic and dermatological uses of an extract of cistus monspeliensis |
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| US20070166275A1 (en) * | 2006-01-19 | 2007-07-19 | Mary Kay Inc. | Compositions comprising kakadu plum extract or acai berry extract |
| CN102014865A (en) * | 2008-05-06 | 2011-04-13 | 赢创高施米特有限公司 | Cosmetics comprising cistus plant extracts |
| CN107929152A (en) * | 2017-12-25 | 2018-04-20 | 广州智媛生物科技有限公司 | Cosmetic composition of sun-proof reparation and preparation method thereof |
| CN108578324A (en) * | 2018-07-02 | 2018-09-28 | 上海新高姿化妆品有限公司 | A kind of skin cream and preparation method thereof with long-acting moisture-keeping efficacy |
| WO2020128223A1 (en) * | 2018-12-21 | 2020-06-25 | Basf Beauty Care Solutions France Sas | Novel cosmetic and dermatological uses of an extract of cistus monspeliensis |
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