CN115667247A - 吡啶类衍生物及其应用 - Google Patents
吡啶类衍生物及其应用 Download PDFInfo
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- CN115667247A CN115667247A CN202180036433.0A CN202180036433A CN115667247A CN 115667247 A CN115667247 A CN 115667247A CN 202180036433 A CN202180036433 A CN 202180036433A CN 115667247 A CN115667247 A CN 115667247A
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- 125000000592 heterocycloalkyl group Chemical group 0.000 claims description 6
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Classifications
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/4433—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a six-membered ring with oxygen as a ring hetero atom
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
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Abstract
本发明公开了一系列带有吡啶结构的化合物或其药学上可接受的盐,及其在制备治疗相关疾病的药物中的应用,具体公开了式(Ι)所示化合物或其药学上可接受的盐。
Description
PCT国内申请,说明书已公开。
Claims (8)
- PCT国内申请,权利要求书已公开。
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
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CN202010444113 | 2020-05-22 | ||
CN2020104441136 | 2020-05-22 | ||
PCT/CN2021/094677 WO2021233349A1 (zh) | 2020-05-22 | 2021-05-19 | 吡啶类衍生物及其应用 |
Publications (2)
Publication Number | Publication Date |
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CN115667247A true CN115667247A (zh) | 2023-01-31 |
CN115667247B CN115667247B (zh) | 2024-04-12 |
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Application Number | Title | Priority Date | Filing Date |
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CN202180036433.0A Active CN115667247B (zh) | 2020-05-22 | 2021-05-19 | 吡啶类衍生物及其应用 |
Country Status (10)
Country | Link |
---|---|
US (1) | US20230183221A1 (zh) |
EP (1) | EP4159730A4 (zh) |
JP (1) | JP7502467B2 (zh) |
KR (1) | KR20230013101A (zh) |
CN (1) | CN115667247B (zh) |
AU (1) | AU2021276287A1 (zh) |
BR (1) | BR112022023732A2 (zh) |
CA (1) | CA3179593A1 (zh) |
MX (1) | MX2022014523A (zh) |
WO (1) | WO2021233349A1 (zh) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN113412261A (zh) * | 2019-04-08 | 2021-09-17 | 四川科伦博泰生物医药股份有限公司 | 苯并咪唑化合物、其制备方法及其用途 |
Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2003014105A1 (en) * | 2001-08-08 | 2003-02-20 | Takeda Chemical Industries, Ltd. | Bicyclic compound, production and use as hiv inhibitors |
CN108289881A (zh) * | 2015-09-16 | 2018-07-17 | 妥必徕疗治公司 | 用于治疗纤维化的赛尼克韦罗联合疗法 |
CN110023286A (zh) * | 2016-12-09 | 2019-07-16 | 南京明德新药研发股份有限公司 | 作为ccr2/ccr5受体拮抗剂的联苯化合物 |
WO2019149089A1 (zh) * | 2018-02-02 | 2019-08-08 | 四川科伦博泰生物医药股份有限公司 | 含有羧酸基团的苯并氮杂环类化合物及其制备方法和用途 |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2001058992A (ja) | 1999-06-16 | 2001-03-06 | Takeda Chem Ind Ltd | ベンゾアゼピン誘導体、その製造法および用途 |
JP2003119191A (ja) | 2001-08-08 | 2003-04-23 | Takeda Chem Ind Ltd | ベンゾアゼピン誘導体、その製造法および用途 |
-
2021
- 2021-05-19 KR KR1020227044558A patent/KR20230013101A/ko unknown
- 2021-05-19 US US17/998,355 patent/US20230183221A1/en active Pending
- 2021-05-19 MX MX2022014523A patent/MX2022014523A/es unknown
- 2021-05-19 WO PCT/CN2021/094677 patent/WO2021233349A1/zh unknown
- 2021-05-19 CA CA3179593A patent/CA3179593A1/en active Pending
- 2021-05-19 CN CN202180036433.0A patent/CN115667247B/zh active Active
- 2021-05-19 BR BR112022023732A patent/BR112022023732A2/pt unknown
- 2021-05-19 EP EP21808699.9A patent/EP4159730A4/en active Pending
- 2021-05-19 AU AU2021276287A patent/AU2021276287A1/en not_active Abandoned
- 2021-05-19 JP JP2022567108A patent/JP7502467B2/ja active Active
Patent Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2003014105A1 (en) * | 2001-08-08 | 2003-02-20 | Takeda Chemical Industries, Ltd. | Bicyclic compound, production and use as hiv inhibitors |
CN108289881A (zh) * | 2015-09-16 | 2018-07-17 | 妥必徕疗治公司 | 用于治疗纤维化的赛尼克韦罗联合疗法 |
CN110023286A (zh) * | 2016-12-09 | 2019-07-16 | 南京明德新药研发股份有限公司 | 作为ccr2/ccr5受体拮抗剂的联苯化合物 |
WO2019149089A1 (zh) * | 2018-02-02 | 2019-08-08 | 四川科伦博泰生物医药股份有限公司 | 含有羧酸基团的苯并氮杂环类化合物及其制备方法和用途 |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN113412261A (zh) * | 2019-04-08 | 2021-09-17 | 四川科伦博泰生物医药股份有限公司 | 苯并咪唑化合物、其制备方法及其用途 |
Also Published As
Publication number | Publication date |
---|---|
EP4159730A4 (en) | 2024-05-01 |
CA3179593A1 (en) | 2021-11-25 |
MX2022014523A (es) | 2022-12-13 |
EP4159730A1 (en) | 2023-04-05 |
WO2021233349A1 (zh) | 2021-11-25 |
AU2021276287A1 (en) | 2023-01-19 |
JP7502467B2 (ja) | 2024-06-18 |
JP2023527678A (ja) | 2023-06-30 |
US20230183221A1 (en) | 2023-06-15 |
KR20230013101A (ko) | 2023-01-26 |
BR112022023732A2 (pt) | 2022-12-20 |
CN115667247B (zh) | 2024-04-12 |
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