CN115624515A - Anti-wrinkle anti-aging mitochondrial composition and application thereof - Google Patents
Anti-wrinkle anti-aging mitochondrial composition and application thereof Download PDFInfo
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
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- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/35—Ketones, e.g. benzophenone
- A61K8/355—Quinones
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/08—Anti-ageing preparations
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Abstract
The invention relates to the field of mitochondrial compositions, in particular to a mitochondrial composition with anti-wrinkle and anti-aging effects and an application thereof, the mitochondrial composition adopts 20-40 parts of cranberry mitochondria, 10-20 parts of aloe mitochondria, 10-15 parts of rose mitochondria, 10-15 parts of chamomile mitochondria, 5-10 parts of olive She Xian mitochondria, 0.5-2 parts of coenzyme Q10, 1-5 parts of squalane, 1-3 parts of shea butter, 0.3-1 part of sodium hyaluronate, 0.1-0.5 part of nicotinamide, 0.1-0.5 part of seaweed gel, 1-3 parts of plant polyphenol, 1-2 parts of plant preservative and the balance of residual water for supplementing, fully mixing, controlling the temperature, sterilizing, filling and using conveniently, and the cosmetic prepared by the composition can quickly supplement the mitochondria of skin cells in the skin cells after being applied to the skin, increase the energy of the cells, promote the oxygen balance in the cells, dynamically convert and protect the skin, and effectively eliminate wrinkles.
Description
Technical Field
The invention relates to the field of mitochondrial compositions, in particular to a mitochondrial composition with anti-wrinkle and anti-aging effects and application thereof.
Background
Mitochondria are the main site of oxygen respiration of cells, provide energy for cell metabolism, the mitochondrial mechanism comprises all enzymes required by the tricarboxylic acid cycle, the tricarboxylic acid cycle can provide sites for the vital activities of cells, the intracellular oxidative phosphorylation and adenosine triphosphate formation are the main sites, the mitochondria are called as a cell power plant, the mitochondria use some organic substances in cells as fuel, the organic substances are converted into carbon dioxide and water through complex processes, chemical components in the organic substances are released for the cells to use, the mitochondria are continuously damaged by oxygen toxicity when using oxygen molecules, so that the dynamic balance of oxygen is difficult to maintain, if the damage of the mitochondria exceeds a limit, the cells are aged, in order to delay the aging of the cells and prevent the skin from generating wrinkles, therefore, a mitochondrial composition is needed to rapidly supplement the mitochondria to the skin cells, promote the energy conversion of the cells, rapidly recover the vitality of the skin cells, recover the elasticity of the skin, prevent the skin from aging and from the wrinkles due to relaxation.
Disclosure of Invention
In view of the above, the invention provides a mitochondrial composition for wrinkle resistance and anti-aging, which is prepared by fully mixing various mitochondrial mixed solutions according to a proportion, so as to supplement mitochondria to skin cells, so that the oxygen dynamic of the cells is more balanced, the energy conversion of the cells is promoted, the skin is younger and firmer, and the skin is prevented from being flaccid and generating wrinkles.
In order to achieve the purpose, the invention adopts the following technical scheme:
a mitochondrial composition for resisting wrinkle and aging comprises: the feed comprises the following raw materials in parts by weight: 20 to 40 parts of cranberry mitochondria, 10 to 20 parts of aloe mitochondria, 10 to 15 parts of rose mitochondria, 10 to 15 parts of chamomile mitochondria, 5 to 10 parts of olive She Xian mitochondria, 0.5 to 2 parts of coenzyme Q10, 1 to 5 parts of squalane, 1 to 3 parts of shea butter, 0.3 to 1 part of sodium hyaluronate, 0.1 to 0.5 part of nicotinamide, 0.1 to 0.5 part of seaweed gel, 1 to 3 parts of plant polyphenol, 1 to 2 parts of plant preservative and the balance of water.
Preferably, the anti-wrinkle anti-aging mitochondrial composition comprises: the feed comprises the following raw materials in parts by weight: 25-35 parts of cranberry mitochondria, 15-20 parts of aloe mitochondria, 12-14 parts of rose mitochondria, 11-13 parts of chamomile mitochondria, 6-9 parts of olive She Xian mitochondria, 0.6-1.5 parts of coenzyme Q10, 2-5 parts of squalane, 1.5-2.5 parts of shea butter, 0.3-1 part of sodium hyaluronate, 0.1-0.5 part of nicotinamide, 0.1-0.3 part of seaweed gel, 1-2 parts of plant polyphenol, 1-1.6 parts of plant preservative and the balance of water.
Preferably, the anti-wrinkle anti-aging mitochondrial composition comprises: 30 parts of cranberry mitochondria, 15 parts of aloe mitochondria, 13 parts of rose mitochondria, 12 parts of chamomile mitochondria, 8 parts of olive She Xian mitochondria, 1.2 parts of coenzyme Q10, 3 parts of squalane, 2 parts of shea butter, 0.6 parts of sodium hyaluronate, 0.3 parts of nicotinamide, 0.3 parts of seaweed gel, 2 parts of plant polyphenol, 1.2 parts of plant preservative and the balance of water.
Preferably, the plant polyphenol is at least one of resveratrol, catechin and anthocyanin.
Preferably, the plant preservative is at least one of anisic acid, a peony root bark extract and a pepper extract.
Preferably, the anti-wrinkle and anti-aging mitochondrial composition further comprises amino acid, 0.5-1 part of lysine, 0.1-0.5 part of glycine and 0.2-0.8 part of arginine according to parts by weight.
A method for preparing an anti-wrinkle and anti-aging mitochondrial composition comprises the following steps:
s1, adding 0.5-2 parts of coenzyme Q10, 1-5 parts of squalane, 1-3 parts of shea butter, 0.3-1 part of sodium hyaluronate, 0.1-0.5 part of nicotinamide, 0.1-0.5 part of seaweed gel, 1-3 parts of plant polyphenol and 1-2 parts of plant preservative into water by mass parts, and stirring for 5-10 min for full mixing to obtain a mixed liquid A;
s2, adding 0.5-1 part by mass of lysine, 0.1-0.5 part by mass of glycine and 0.2-0.8 part by mass of arginine into the mixed liquid A, fully mixing, and then precooling to 0 ℃ to obtain mixed liquid B;
s3, respectively extracting 20-40 parts by mass of cranberry mitochondria, 10-20 parts by mass of aloe mitochondria, 10-15 parts by mass of rose mitochondria, 10-15 parts by mass of chamomile mitochondria and 5-10 parts by mass of olive She Xian mitochondria to be added into a mitochondria storage liquid to form a mitochondria mixed liquid, then adding the mitochondria mixed liquid into the mixed liquid B to be fully mixed to obtain a mixed liquid C, and then adding a skin penetration agent into the mixed liquid C;
and S4, sterilizing the mixed liquid C, and filling to obtain the anti-wrinkle anti-aging mitochondrial composition.
Preferably, in S3 the skin penetration agent is azone or caprylic/capric triglyceride.
Preferably, the invention also provides application of the anti-wrinkle and anti-aging mitochondrial composition in preparation of skin care products.
Preferably, the skin care product is common skin care product types, including toner, facial mask, essence, lotion, face cleanser or cream.
Compared with the prior art, the invention has the beneficial effects that: the invention extracts various plant mitochondria as main raw materials, and fully mixes the plant mitochondria with various other raw materials through scientific proportioning to obtain the mitochondria composition, and the mitochondria composition can be applied to common skin care products to quickly supplement the mitochondria in skin cells, so that the dynamic balance of oxygen in the cells is improved, the cell aging is delayed, the skin aging is further delayed, the skin is enabled to recover compact and young, wrinkles are lightened, even the wrinkles are eliminated, and the skin health is comprehensively and effectively cared.
Detailed Description
In order to make those skilled in the art better understand the technical solutions in the present application, the following will clearly and completely describe the technical solutions in the present application with reference to the embodiments, and it is obvious that the described embodiments are only a part of the embodiments of the present application, and all other embodiments obtained by a person of ordinary skill in the art without making creative efforts based on the embodiments in the present application shall fall within the protection scope of the present application.
In example 1, the skin permeation agent is azone or caprylic/capric triglyceride.
A method for preparing an anti-wrinkle and anti-aging mitochondrial composition comprises the following steps:
s1, adding 1.2 parts of coenzyme Q10, 3 parts of squalane, 2 parts of shea butter, 0.7 part of sodium hyaluronate, 0.3 part of nicotinamide, 0.2 part of seaweed gel, 2 parts of plant polyphenol and 1.6 parts of plant preservative into water in parts by mass, and stirring for 5-10 min for full mixing to obtain a mixed liquid A;
s2, adding 0.7 part of lysine, 0.5 part of glycine and 0.3 part of arginine into the mixed liquid A in parts by mass, fully mixing, and then precooling to 0 ℃ to obtain mixed liquid B;
s3, respectively extracting 35 parts by mass of cranberry mitochondria, 18 parts by mass of aloe mitochondria, 13 parts by mass of rose mitochondria, 12 parts by mass of chamomile mitochondria and 8 parts by mass of olive She Xian mitochondria to form a mitochondria mixed solution, adding the mitochondria mixed solution into the mixed solution B to be fully mixed to obtain a mixed solution C, and adding a skin-penetrating agent into the mixed solution C;
and S4, sterilizing and filling the mixed liquid C to obtain the anti-wrinkle anti-aging mitochondrial composition.
In example 2, the skin permeation agent is azone or caprylic/capric triglyceride.
A method for preparing an anti-wrinkle and anti-aging mitochondrial composition comprises the following steps:
s1, adding 1.3 parts of coenzyme Q10, 2.5 parts of squalane, 1.8 parts of shea butter, 0.5 part of sodium hyaluronate, 0.2 part of nicotinamide, 0.3 part of seaweed gel, 1 part of plant polyphenol and 1.2 parts of plant preservative into water by mass parts, and stirring for 5-10 min for full mixing to obtain a mixed liquid A;
s2, adding 0.6 part of lysine, 0.3 part of glycine and 0.5 part of arginine into the mixed liquid A in parts by mass, fully mixing, and then precooling to 0 ℃ to obtain mixed liquid B;
s3, respectively extracting 30 parts by mass of cranberry mitochondria, 15 parts by mass of aloe mitochondria, 14 parts by mass of rose mitochondria, 13 parts by mass of chamomile mitochondria and 9 parts by mass of olive She Xian mitochondria to form a mitochondria mixed solution, adding the mitochondria mixed solution into the mixed solution B to be fully mixed to obtain a mixed solution C, and adding a skin-penetrating agent into the mixed solution C;
and S4, sterilizing the mixed liquid C, and filling to obtain the anti-wrinkle anti-aging mitochondrial composition.
In example 3, the skin permeation agent is azone or caprylic/capric triglyceride.
A method for preparing an anti-wrinkle and anti-aging mitochondrial composition comprises the following steps:
s1, adding 1.5 parts of coenzyme Q10, 4 parts of squalane, 2.5 parts of shea butter, 0.3 part of sodium hyaluronate, 0.4 part of nicotinamide, 0.5 part of seaweed gel, 2.3 parts of plant polyphenol and 1.1 part of plant preservative into water by mass parts, and stirring for 5-10 min for full mixing to obtain a mixed liquid A
S2, adding 0.8 part of lysine, 0.4 part of glycine and 0.4 part of arginine into the mixed liquid A in parts by mass, fully mixing, and then precooling to 0 ℃ to obtain mixed liquid B;
s3, respectively extracting 40 parts by mass of cranberry mitochondria, 20 parts by mass of aloe mitochondria, 15 parts by mass of rose mitochondria, 15 parts by mass of chamomile mitochondria and 10 parts by mass of olive She Xian mitochondria to form a mitochondria mixed solution, adding the mitochondria mixed solution into the mixed solution B to be fully mixed to obtain a mixed solution C, and adding a skin-penetrating agent into the mixed solution C;
and S4, sterilizing the mixed liquid C, and filling to obtain the anti-wrinkle anti-aging mitochondrial composition.
In comparative example 1, the skin permeation agent was azone or caprylic/capric triglyceride.
A method for preparing an anti-wrinkle and anti-aging composition comprises the following steps:
s1, adding 1.2 parts of coenzyme Q10, 3 parts of squalane, 2 parts of shea butter, 0.7 part of sodium hyaluronate, 0.3 part of nicotinamide, 0.2 part of seaweed gel, 2 parts of plant polyphenol and 1.6 parts of plant preservative into water in parts by mass, and stirring for 5-10 min for full mixing to obtain a mixed liquid A;
s2, adding 0.7 part of lysine, 0.5 part of glycine and 0.3 part of arginine into the mixed liquid A in parts by mass, fully mixing, and then precooling to 0 ℃ to obtain mixed liquid B;
s3, adding a skin penetrating agent into the mixed liquid B, and mixing to obtain a mixed liquid C;
and S4, sterilizing and filling the mixed liquid C to obtain the anti-wrinkle and anti-aging composition.
In comparative example 2, the skin permeation agent was azone or caprylic/capric triglyceride.
S1, adding 3 parts by mass of squalane, 2 parts by mass of shea butter, 0.7 part by mass of sodium hyaluronate, 0.3 part by mass of nicotinamide, 0.2 part by mass of seaweed gel, 2 parts by mass of plant polyphenol and 1.6 parts by mass of preservative into water, and stirring for 5-10 min for full mixing to obtain mixed liquid A;
s2, adding 3 parts by mass of lysine, 1.5 parts by mass of glycine and 1.5 parts by mass of arginine into the mixed liquid A, fully mixing, and then precooling to 0 ℃ to obtain mixed liquid B;
s3, respectively extracting 35 parts by mass of cranberry mitochondria, 18 parts by mass of aloe mitochondria, 13 parts by mass of rose mitochondria, 12 parts by mass of chamomile mitochondria and 8 parts by mass of olive She Xian mitochondria to form a mitochondria mixed solution, adding the mitochondria mixed solution into the mixed solution B to be fully mixed to obtain a mixed solution C, and adding a skin-penetrating agent into the mixed solution C;
and S4, sterilizing and filling the mixed liquid C to obtain the anti-wrinkle anti-aging mitochondrial composition.
The following experiments were carried out to demonstrate the effect of mitochondrial compositions in supplementing energy to body cells:
effect examples of the present invention the scavenging ability of the products obtained in examples 1 to 3 and comparative examples 1 to 2 for radicals was investigated, wherein the scavenging ability for DPPH radicals, superoxide anion radicals and hydroxyl radicals and skin tolerance tests were mainly investigated: female volunteers aged 35-50 years are randomly selected, 5 groups are set, 10 persons in each group are tried on the face creams prepared in examples 1-3 and comparative examples 1-2 respectively, and the skin state of the corresponding test sample after the trial of the test sample for 10min is observed, wherein the comparative example 1 is prepared by taking no mitochondria as a raw material, the comparative example 2 is prepared by taking a chemical preservative as a raw material instead of a plant preservative, and the results are shown in the following table:
the above results show that the creams prepared from the mitochondrial compositions according to examples 1-3 and comparative example 2 of the present invention have strong free radical scavenging ability, and exhibit significant scavenging inhibition effects on DPPH free radicals, superoxide anion free radicals and hydroxyl free radicals, and as can be seen from comparison of comparative example 1 between examples 1-3 and comparative example 2, under the same conditions, the removal rate of free radicals is significantly lower than that of the composition according to the present invention without using mitochondria as a raw material, and as can be seen from examples 1-3 and comparative example 2, the absence of using a plant preservative as a raw material causes skin allergy of two persons in the test to cause redness and swelling, which indicates that irritation to the skin can be reduced by using a plant preservative as a raw material, which indicates that the creams prepared according to the present invention have improved affinity to human skin while achieving free radical scavenging.
Selecting 50 volunteers with healthy skin, no skin allergy history, poor skin state and loose skin to participate in a test, wherein 25 female volunteers and 25 male volunteers are 25-40 years old and randomly divided into 5 groups according to sex, age and the like, 10 people in each group respectively try the essence prepared by the mitochondrial composition prepared in the embodiments 1-3 and the comparative examples 1-2, wherein the comparative example 1 is prepared by not adding mitochondria as a raw material, the comparative example 2 is prepared by not adding coenzyme Q10 as a raw material, during the trial period, cleaning the smeared part with clear water in the morning and evening, then coating a proper amount of the composition on the skin, trying for two weeks, and after the trial period is finished, evaluating the anti-wrinkle and anti-aging effects of the essence by each volunteer, wherein the effects are four, including ineffective, common, effective and very effective, and then counting the number of the test results are shown in the following table:
the results show that the essence prepared from the composition containing mitochondria as raw materials has obvious anti-aging and anti-wrinkle effects compared with the comparative example 1, the number of very effective people is more than 7, the essence prepared from the composition containing mitochondria as raw materials has very good anti-aging and anti-wrinkle effects, the effect of the embodiment 1-3 has no invalid people compared with the comparative example 2, the synergistic use of mitochondria and coenzyme Q10 can improve the skin improving effect, and the essence prepared from the anti-wrinkle and anti-aging mitochondria composition disclosed by the invention is proved to have quick response and good effect after being used, can quickly supplement mitochondria to skin cells, provide power for the cells, improve the dynamic balance of oxygen in the cells, delay the aging of the cells, further delay the skin aging, enable the skin to be compact and recover and young, lighten wrinkles, even eliminate wrinkles and comprehensively and effectively protect the healthy skin.
Mitochondria are sites which directly use oxygen to produce energy, more than 90% of the oxygen absorbed into the body is consumed by the mitochondria, however, the oxygen is a 'double-edged sword', on one hand, organisms use oxygen molecules to produce energy, on the other hand, the oxygen molecules can generate extremely active intermediates (active oxygen free radicals) to hurt the organisms to cause oxygen toxicity in the process of being used, the organisms try to live and develop in continuous fight with the oxygen toxicity, the oxygen toxicity is the most initial reason for organism aging, the mitochondria are continuously damaged by the oxygen molecules while using the oxygen molecules, the damage of the mitochondria exceeds a certain limit, and the cells can die, therefore, the mitochondria are added into an anti-aging and anti-wrinkle composition to be made into cosmetics, and can rapidly supplement the mitochondria into skin cells, promote the energy conversion of the cells, prevent the aging of the cells, enable the skin to be firmer, eliminate wrinkles and recover young.
It should be noted that: the coenzyme Q10 has the main anti-wrinkle effect in cosmetics, and the action mechanism is as follows: the coenzyme Q10 promotes the respiratory chain transmission of epithelial cells of the face and the hand and the generation of ATP, thereby promoting the metabolism of the skin, eliminating the skin stress caused by aging, lack of nutrition, illumination and diseases, simultaneously inhibiting the peroxidation of skin lipid, playing a role in nourishing and activating the skin, and recovering the coenzyme Q10 content in epidermal cells is an effective method for smoothing wrinkles and restoring the youth of the face.
The present invention is not limited to the details of the above-described exemplary embodiments, and may be embodied in other specific forms without departing from the spirit or essential characteristics thereof. The present embodiments are therefore to be considered in all respects as illustrative and not restrictive, the scope of the invention being indicated by the appended claims rather than by the foregoing description, and all changes which come within the meaning and range of equivalency of the claims are therefore intended to be embraced therein.
Claims (10)
1. A mitochondrial composition for wrinkle resistance and aging resistance, which is characterized by comprising the following components in percentage by weight: the feed comprises the following raw materials in parts by weight: 20 to 40 parts of cranberry mitochondria, 10 to 20 parts of aloe mitochondria, 10 to 15 parts of rose mitochondria, 10 to 15 parts of chamomile mitochondria, 5 to 10 parts of olive She Xian mitochondria, 0.5 to 2 parts of coenzyme Q10, 1 to 5 parts of squalane, 1 to 3 parts of shea butter, 0.3 to 1 part of sodium hyaluronate, 0.1 to 0.5 part of nicotinamide, 0.1 to 0.5 part of seaweed gel, 1 to 3 parts of plant polyphenol, 1 to 2 parts of plant preservative and the balance of water.
2. The anti-wrinkle anti-aging mitochondrial composition according to claim 1, wherein: the feed comprises the following raw materials in parts by weight: 25-35 parts of cranberry mitochondria, 15-20 parts of aloe mitochondria, 12-14 parts of rose mitochondria, 11-13 parts of chamomile mitochondria, 6-9 parts of olive She Xian mitochondria, 0.6-1.5 parts of coenzyme Q10, 2-5 parts of squalane, 1.5-2.5 parts of shea butter, 0.3-1 part of sodium hyaluronate, 0.1-0.5 part of nicotinamide, 0.1-0.3 part of seaweed gel, 1-2 parts of plant polyphenol, 1-1.6 parts of plant preservative and the balance of water.
3. The anti-wrinkle anti-aging mitochondrial composition according to claim 1, wherein: the feed comprises the following raw materials in parts by weight: 30 parts of cranberry mitochondria, 15 parts of aloe mitochondria, 13 parts of rose mitochondria, 12 parts of chamomile mitochondria, 8 parts of olive She Xian mitochondria, 1.2 parts of coenzyme Q10, 3 parts of squalane, 2 parts of shea butter, 0.6 parts of sodium hyaluronate, 0.3 parts of nicotinamide, 0.3 parts of seaweed gel, 2 parts of plant polyphenol, 1.2 parts of plant preservative and the balance of water.
4. The anti-wrinkle anti-aging mitochondrial composition according to claim 3, wherein: the plant polyphenol is at least one of resveratrol, catechin and anthocyanin.
5. The anti-wrinkle anti-aging mitochondrial composition according to claim 3, wherein: the plant preservative is at least one of anisic acid, a peony root bark extract and a pepper extract.
6. The anti-wrinkle anti-aging mitochondrial composition according to claim 1, wherein: the anti-wrinkle anti-aging mitochondrial composition also comprises amino acid, 0.5-1 part of lysine, 0.1-0.5 part of glycine and 0.2-0.8 part of arginine according to parts by weight.
7. A preparation method of a mitochondrial composition for resisting wrinkles and aging is characterized by comprising the following steps: the method comprises the following steps:
s1, adding 0.5-2 parts of coenzyme Q10, 1-5 parts of squalane, 1-3 parts of shea butter, 0.3-1 part of sodium hyaluronate, 0.1-0.5 part of nicotinamide, 0.1-0.5 part of seaweed gel and 1-3 parts of plant polyphenol into water by mass, and stirring for 5-10 min for full mixing to obtain a mixed liquid A;
s2, adding 0.5-1 part by mass of lysine, 0.1-0.5 part by mass of glycine and 0.2-0.8 part by mass of arginine into the mixed liquid A, fully mixing, and then precooling to 0 ℃ to obtain mixed liquid B;
s3, respectively extracting 20-40 parts by mass of cranberry mitochondria, 10-20 parts by mass of aloe mitochondria, 10-15 parts by mass of rose mitochondria, 10-15 parts by mass of chamomile mitochondria and 5-10 parts by mass of olive She Xian mitochondria to be added into a mitochondria storage liquid to form a mitochondria mixed liquid, then adding the mitochondria mixed liquid into the mixed liquid B to be fully mixed to obtain a mixed liquid C, and then adding a skin penetration agent into the mixed liquid C;
and S4, sterilizing and filling the mixed liquid C to obtain the anti-wrinkle anti-aging mitochondrial composition.
8. The method for preparing the mitochondrial composition for anti-wrinkle and anti-aging according to claim 7, wherein the skin-penetrating agent in S3 is azone or caprylic/capric triglyceride.
9. Use of a restorative anti-ageing composition according to any of claims 1 to 3 in the preparation of a skin care product.
10. The use of claim 9, wherein the skin care product is a toner, a mask, a serum, a lotion, a cleanser, or a cream.
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| WO2020214644A1 (en) * | 2019-04-15 | 2020-10-22 | Children's Medical Center Corporation | Aerosolized compositions comprising mitochondria and methods of use thereof |
| CN111166707A (en) * | 2020-01-19 | 2020-05-19 | 广州市柏姿生物科技有限公司 | Facial anti-aging repairing and nursing composition and preparation method and application thereof |
| CN114224768A (en) * | 2021-12-13 | 2022-03-25 | 江苏江山聚源生物技术有限公司 | Repairing and anti-aging composition and preparation method thereof |
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