CN115624501A - Skin conditioning composition - Google Patents

Skin conditioning composition Download PDF

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Publication number
CN115624501A
CN115624501A CN202211478778.4A CN202211478778A CN115624501A CN 115624501 A CN115624501 A CN 115624501A CN 202211478778 A CN202211478778 A CN 202211478778A CN 115624501 A CN115624501 A CN 115624501A
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Prior art keywords
extract
skin
conditioning composition
component
skin conditioning
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Pending
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CN202211478778.4A
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Chinese (zh)
Inventor
袁玉梅
谢静红
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Suzhou Riyuenianshi Biotechnology Co ltd
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Suzhou Riyuenianshi Biotechnology Co ltd
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Publication of CN115624501A publication Critical patent/CN115624501A/en
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/73Polysaccharides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/34Alcohols
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/34Alcohols
    • A61K8/345Alcohols containing more than one hydroxy group
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/49Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
    • A61K8/494Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with more than one nitrogen as the only hetero atom
    • A61K8/4953Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with more than one nitrogen as the only hetero atom containing pyrimidine ring derivatives, e.g. minoxidil
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/60Sugars; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9728Fungi, e.g. yeasts
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9783Angiosperms [Magnoliophyta]
    • A61K8/9789Magnoliopsida [dicotyledons]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9783Angiosperms [Magnoliophyta]
    • A61K8/9794Liliopsida [monocotyledons]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/99Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from microorganisms other than algae or fungi, e.g. protozoa or bacteria
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/10Anti-acne agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/005Preparations for sensitive skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/20Chemical, physico-chemical or functional or structural properties of the composition as a whole
    • A61K2800/30Characterized by the absence of a particular group of ingredients

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  • Health & Medical Sciences (AREA)
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  • Chemical Kinetics & Catalysis (AREA)
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  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Cosmetics (AREA)
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Abstract

The invention discloses a skin conditioning composition which comprises skin cutin conditioning components, relieving and anti-inflammatory components, antioxidant components, repairing and conditioning components and microorganism conditioning components. Through the mode, the skin conditioning composition does not contain acidic substances such as alpha-hydroxy acid, beta-hydroxy acid and polyhydroxy acid, is suitable for sensitive muscles, has the acne removing effect, provides more choices for consumers, and has wide market prospects.

Description

Skin conditioning composition
Technical Field
The invention relates to the technical field of cosmetic compositions and preparation thereof, in particular to a skin conditioning composition.
Background
Acne is commonly known as whelk, pimple and comedo, and is an infectious inflammation of hair follicle sebaceous glands. Skin acne can be caused by in vivo reasons such as sebum activation, digestive function disorder and trace element intake insufficiency caused by endocrine dyscrasia, and skin water and oil imbalance, follicular orifice keratinization hyperfunction, bacterial factors and other external reasons can also cause skin acne. At present, a part of skin conditioning compositions with an acne removing function on the market contain acidic substances such as alpha-hydroxy acid, beta-hydroxy acid and polyhydroxy acid, the acidic substances in the skin conditioning compositions can damage the barrier structure of the skin, the other part of the skin conditioning compositions contain broad-spectrum bactericidal components, the acne removing effect is poor, the microbial environment of the skin is damaged, the skin conditioning compositions are not good in acne removing effect and cannot be applied to sensitive muscles, the applicable crowd range is narrow, and the wide sale is influenced.
Disclosure of Invention
The invention mainly solves the technical problem of providing a skin conditioning composition with good use effect.
In order to solve the technical problems, the invention adopts a technical scheme that: a skin conditioning composition is provided which includes as components a skin cutin conditioning component, a soothing anti-inflammatory component, an antioxidant component, a rejuvenating conditioning component, a microorganism regulating component.
In a preferred embodiment of the present invention, the skin conditioning composition comprises the following components in parts by weight: 0.1 to 15 parts of skin cutin conditioning component, 5 to 60 parts of relieving and anti-inflammatory component, 0.1 to 10 parts of antioxidant component, 1 to 15 parts of repairing and conditioning component and 0.01 to 30 parts of microorganism conditioning component.
In a preferred embodiment of the invention, the skin conditioning composition is free of acidic materials.
In a preferred embodiment of the present invention, the acidic substance includes, but is not limited to, one or more of α -hydroxy acid, β -hydroxy acid, and polyhydroxy acid.
In a preferred embodiment of the present invention, the skin keratolytic ingredient includes, but is not limited to, one or more of cactus extract, cactus flower extract, castanea sativa extract, lyme extract, yarrow extract, cedar bud extract, and bacillus fermentation product.
In a preferred embodiment of the present invention, the anti-inflammatory and soothing component includes, but is not limited to, one or more of dracaena extract, syringa vulgaris extract, microbial fermentation product, centella asiatica extract, sunflower extract, and ophiopogon japonicus extract.
In a preferred embodiment of the present invention, the antioxidant component comprises, but is not limited to, one or more of totarol, olive extract, tocopherol.
In a preferred embodiment of the present invention, the conditioning ingredient comprises but is not limited to one or more of inositol, oligopeptide, ectoin, zinc salt.
In a preferred embodiment of the present invention, the microorganism-regulating component includes, but is not limited to, one or more of saccharide isomerate, inulin and fructose.
The invention has the beneficial effects that: the skin conditioning composition does not contain acidic substances such as alpha-hydroxy acid, beta-hydroxy acid and polyhydroxy acid, is suitable for sensitive muscles, has an acne removing effect, provides more choices for consumers, and has a wide market prospect.
Drawings
In order to more clearly illustrate the technical solutions in the embodiments of the present invention, the drawings needed to be used in the description of the embodiments are briefly introduced below, it is obvious that the drawings in the following description are only some embodiments of the present invention, and other drawings can be obtained by those skilled in the art without inventive efforts, wherein:
FIG. 1 is a comparative facial image of a subject before and after use of a skin conditioning composition of the present invention;
FIG. 2 is a table showing the results of measurement of vaccinia a in subjects;
FIG. 3 is a bar graph of vaccinia a test in subjects;
FIG. 4 is a table showing the results of measurement of the moisture content of stratum corneum of a subject;
FIG. 5 is a bar graph of the results of a test of the water content of the stratum corneum of a subject;
FIG. 6 is a table of the results of the skin oil content measurements of the subjects;
FIG. 7 is a bar graph of skin oil content measurements of a subject;
FIG. 8 is a table of results of physician clinical assessment (IGA) of subjects;
figure 9 is a bar graph of the results of physician clinical assessment (IGA) of subjects.
Detailed Description
The technical solutions in the embodiments of the present invention will be clearly and completely described below, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
The first embodiment is as follows:
a skin conditioning composition is provided which includes components including a skin cutin conditioning component, a soothing anti-inflammatory component, an antioxidant component, a rejuvenating conditioning component, and a microorganism conditioning component. The skin conditioning composition comprises the following specific components in percentage by mass: 0.15% of xanthan gum, 5% of glycerol, 0.5% of 1, 2-hexanediol, 0.5% of phenoxyethanol, 1% of bacillus fermentation product, 0.2% of syringa vulgaris extract, 10% of yeast fermentation product, 1% of olive extract, 0.5% of ectoin, 5% of saccharide isomer and the addition of water to 100%.
The second embodiment:
a skin conditioning composition is provided which includes as components a skin cutin conditioning component, a soothing anti-inflammatory component, an antioxidant component, a rejuvenating conditioning component, a microorganism regulating component. The skin conditioning composition comprises the following specific components in percentage by mass: 0.15% of xanthan gum, 5% of glycerol, 0.5% of 1, 2-hexanediol, 0.5% of phenoxyethanol, 2% of cactus extract, 2% of cryptomeria fortunei bud extract, 0.5% of dracaena japonica extract, 0.2% of radix ophiopogonis extract, 5% of sunflower extract, 1% of olive extract, 1% of ectoine, 1% of fructose and the addition amount of water of 100%.
Example three:
a skin conditioning composition is provided which includes components including a skin cutin conditioning component, a soothing anti-inflammatory component, an antioxidant component, a rejuvenating conditioning component, and a microorganism conditioning component. The skin conditioning composition comprises the following specific components in percentage by mass: 0.15% of xanthan gum, 5% of propylene glycol, 0.3% of p-hydroxyacetophenone, 0.5% of phenoxyethanol, 1% of bacillus fermentation product, 0.4% of radix ophiopogonis extract, 8% of sunflower extract, 0.5% of totarol, 0.2% of oligopeptide, 5% of saccharide isomer and the addition of water to 100%.
Example four:
the skin conditioning composition of embodiment one, comprising the steps of: (1) Uniformly dispersing xanthan gum with glycerol, adding water, heating to 80 deg.C, stirring, and swelling; (2) Cooling to 50 deg.C, stirring, and adding 1, 2-hexanediol and phenoxyethanol; (3) Cooling to 40 deg.C, adding the rest components one by one, stirring to dissolve, and mixing well to obtain skin conditioning composition.
Example five:
33 recruited facial skins had acne grade 1-2 and met the Tell>10g/h/m 2 Using the skin conditioning composition obtained in example one, tests were performed on changes in moisture content of the stratum corneum, pox a value, soothing a value, heme content, skin oil content, and clinical assessment by a physician before and after use to evaluate the efficacy of a repair, soothing, moisturizing, oil management, anti-acne cosmetic.
The instruments used for the test were: (1) facial image analyzer VISIA (canfeild, usa); (2) Skin moisture tester Probe Corneometer CM825 (CK, germany); (3) Skin melanin and heme tester Probe Mexameter MX18 (CK, germany); (4) Skin oil tester Sebumeter (CK, germany)
The results of the specific tests are shown in figures 1-9, where figure 1 is a comparison of the face of a subject before and after application of the skin conditioning composition. The results of the vaccinia a test on the subjects are shown in the table of fig. 2, which shows a significant 10.85% reduction in the skin conditioning composition, with the bar chart shown in fig. 3, which is shown on the left of fig. 3 as the baseline value and on the right as the 14-day post-product. The results of the test of the water content in the stratum corneum of the subjects are shown in the table of fig. 4, which shows that there is a significant change of 20.19% increase after the product skin conditioning composition is applied, and the specific change is shown in the bar chart of fig. 5, where the left side of the chart is the base value and the right side is the value after the product is applied for 14 days. The results of the skin oil content test of the subjects are shown in the table of fig. 6, which shows that there is a significant change of 69.47% reduction after the product skin conditioning composition is applied, and the specific change is shown in the bar chart of fig. 7, where the left side of the chart is the base value and the right side is the value after the product is applied for 14 days. Results of physician clinical assessment (IGA) of the subjects are shown in the table of FIG. 8, showing a significant 58.74% reduction after the product skin conditioning composition was applied, and a bar graph is shown in FIG. 9, with the base values on the left and the values after 14 days of application of the product on the right in FIG. 9.
The above description is only an embodiment of the present invention, and not intended to limit the scope of the present invention, and all modifications of equivalent structures and equivalent processes, which are made by the present specification, or directly or indirectly applied to other related technical fields, are included in the scope of the present invention.

Claims (9)

1. A skin conditioning composition characterized in that said skin conditioning composition comprises the components of a skin cutin conditioning component, a soothing anti-inflammatory component, an antioxidant component, a rejuvenating conditioning component, and a microorganism-regulating component.
2. The skin conditioning composition according to claim 1, wherein the skin conditioning composition comprises the following components in parts by weight: 0.1 to 15 parts of skin cutin conditioning component, 5 to 60 parts of relieving and anti-inflammatory component, 0.1 to 10 parts of antioxidant component, 1 to 15 parts of repairing and conditioning component and 0.01 to 30 parts of microorganism conditioning component.
3. The skin conditioning composition of claim 1, wherein the skin conditioning composition is free of an acidic material.
4. A skin conditioning composition according to claim 3, characterised in that the acidic material comprises one or more of, but is not limited to, an alpha hydroxy acid, a beta hydroxy acid, a polyhydroxy acid.
5. The skin conditioning composition of claim 1, wherein the skin cutin conditioning ingredient comprises one or more of but not limited to cactus extract, cactus flower extract, chestnut extract, lime extract, yarrow extract, cedar bud extract, bacillus fermentation product.
6. The skin conditioning composition of claim 1, wherein the soothing anti-inflammatory ingredient comprises one or more of, but is not limited to, a dragon tree extract, a syringa vulgaris extract, a microbial fermentation product, a centella asiatica extract, a sunflower extract, and an ophiopogon japonicus extract.
7. The skin conditioning composition of claim 1, wherein the antioxidant ingredient comprises one or more of, but not limited to, totarol, olive extract, tocopherol.
8. The skin conditioning composition of claim 1 wherein the rejuvenating conditioning ingredients include but are not limited to one or more of inositol, oligopeptides, ectoin, zinc salts.
9. A skin conditioning composition according to claim 1, characterized in that the micro-organism regulating ingredient comprises but is not limited to one or several of saccharide isomerate, inulin, fructose.
CN202211478778.4A 2022-11-24 2022-11-24 Skin conditioning composition Pending CN115624501A (en)

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Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110638728A (en) * 2019-11-14 2020-01-03 广州一一生物技术有限公司 Skin care composition for removing acne and lightening acne marks and preparation method and application thereof
CN111202769A (en) * 2020-03-04 2020-05-29 云南贝泰妮生物科技集团股份有限公司 Composition and preparation for acne rosacea and preparation method thereof
CN111388405A (en) * 2020-05-26 2020-07-10 广州雅纯化妆品制造有限公司 Oil-control acne-removing composition
CN111991309A (en) * 2020-08-20 2020-11-27 广州优理氏生物科技有限公司 Composition with repairing and moisturizing effects and preparation method and application thereof
CN112294724A (en) * 2020-11-18 2021-02-02 美丽链接生物科技研究院(广东)有限公司 Ice cream-like scrub cream with acne removing effect

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110638728A (en) * 2019-11-14 2020-01-03 广州一一生物技术有限公司 Skin care composition for removing acne and lightening acne marks and preparation method and application thereof
CN111202769A (en) * 2020-03-04 2020-05-29 云南贝泰妮生物科技集团股份有限公司 Composition and preparation for acne rosacea and preparation method thereof
CN111388405A (en) * 2020-05-26 2020-07-10 广州雅纯化妆品制造有限公司 Oil-control acne-removing composition
CN111991309A (en) * 2020-08-20 2020-11-27 广州优理氏生物科技有限公司 Composition with repairing and moisturizing effects and preparation method and application thereof
CN112294724A (en) * 2020-11-18 2021-02-02 美丽链接生物科技研究院(广东)有限公司 Ice cream-like scrub cream with acne removing effect

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
天津市贝禧美商贸有限公司: "YOUMU优慕依克多因焕颜精华液", Retrieved from the Internet <URL:https://hzpba.nmpa.gov.cn/gccx/chakanHis.html?prodId=20200713161447yixe9&gb=G> *

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