CN115531489A

CN115531489A - Scar-removing traditional Chinese medicine composition and preparation method thereof

Info

Publication number: CN115531489A
Application number: CN202211036062.9A
Authority: CN
Inventors: 叶日生; 翁兴立; 柴林姓
Original assignee: Zhejiang Jinzhen Health Technology Co ltd
Current assignee: Zhejiang Jinzhen Health Technology Co ltd
Priority date: 2022-08-27
Filing date: 2022-08-27
Publication date: 2022-12-30

Abstract

The application provides a scar-removing traditional Chinese medicine composition and a preparation method thereof, and relates to the technical field of traditional Chinese medicines. The scar-removing traditional Chinese medicine composition comprises the following raw materials in parts by weight: 3-6 parts of sculellaria barbata, 1-2 parts of circium japonicum, 1-2 parts of paris polyphylla, 3-6 parts of astragalus membranaceus, 1-2 parts of ginseng, 2-4 parts of angelica sinensis, 1-2 parts of liquorice, 2-4 parts of bletilla striata, 2-4 parts of white muscardine silkworm, 2-4 parts of polygonatum odoratum, 1-2 parts of coptis chinensis, 1-2 parts of radix scutellariae and 2-4 parts of dendrobe. The raw materials are wide in source and low in price and are easy to obtain, and the synergistic effect of the raw materials has the effects of clearing away heat and toxic materials, promoting blood circulation to remove blood stasis, relieving distension and fullness and dissipating stagnation, can eliminate various scars, has no toxic or side effect and no stimulation to skin, also has the effects of protecting skin and resisting bacteria, and can play a role in moistening and nourishing. The preparation method is simple, is convenient for mass production, can greatly extract the effective components in the Chinese herbal medicines, is prepared into a paste shape, is convenient to apply and carry, and has good treatment effect on scars.

Description

Scar-removing traditional Chinese medicine composition and preparation method thereof

Technical Field

The application relates to the technical field of traditional Chinese medicines, and particularly relates to a scar-removing traditional Chinese medicine composition and a preparation method thereof.

Background

Scars, also known as scars, are a collective term for the morphological and histopathological changes in normal skin tissue that occur after various traumas. It is a normal and inevitable physiological reaction in the natural healing process of wounds or wound surfaces after human body trauma, and is also an inevitable result of the healing process of the wounds. The nature of a scar is an abnormal, incompetent tissue without normal skin tissue structure and physiological function, which loses normal tissue vitality. When the growth of scars exceeds a certain limit, various complications can be caused, such as disfigurement, dysfunction and the like, and great physical pain and mental pain can be caused, particularly scars left after burns, scalds and serious trauma.

The current methods for treating scars mainly comprise the following methods: 1. glucocorticoid is injected into skin lesions, which is the most widely applied treatment method at present, can soften scars, reduce skin rash and needs multiple injections; 2. cryotherapy, which is suitable for relatively small scars and may cause delayed healing of the wound surface or pigmentation and the like if being used excessively; 3. surgical treatment, such as excision surgery and skin grafting surgery, has high surgical cost, the wound can not be contacted with water, the normal life of a patient is affected, and scars are easy to relapse; 4. laser therapy, which can relieve scar hyperplasia, has poor effect and is difficult to completely recover; 5. smearing chemical medicines: the scar hyperplasia can be prevented by applying chemical medicines on the skin, but the components with side effects on human bodies, such as heavy metals, hormones and the like are often added in the scar hyperplasia, are not easy to absorb after being applied, are easy to lose efficacy after meeting water, and have poor effects on scar pigmentation, striae gravidarum and the like.

Disclosure of Invention

The application aims to provide a scar-removing traditional Chinese medicine composition. The raw materials are wide in source, low in price and easy to obtain, and all the raw materials have the effects of clearing away heat and toxic materials, promoting blood circulation to remove blood stasis, relieving distension and fullness and dispersing stagnation under the synergistic effect, can eliminate various scars, and has no toxic or side effect and no stimulation to skin.

Another objective of the present application is to provide a preparation method of the scar-removing traditional Chinese medicine composition, which is simple, convenient for mass production, capable of greatly extracting effective components from Chinese herbal medicines, prepared into paste, convenient for smearing, convenient for carrying, and has a good treatment effect on scars.

The technical problem to be solved by the application is solved by adopting the following technical scheme.

On one hand, the embodiment of the application provides a scar-removing traditional Chinese medicine composition which comprises the following raw materials in parts by weight:

3-6 parts of sculellaria barbata, 1-2 parts of Japanese thistle herb, 1-2 parts of paris polyphylla, 3-6 parts of astragalus membranaceus, 1-2 parts of ginseng, 2-4 parts of angelica sinensis, 1-2 parts of liquorice, 2-4 parts of bletilla striata, 2-4 parts of silkworm larva, 2-4 parts of polygonatum odoratum, 1-2 parts of coptis chinensis, 1-2 parts of radix scutellariae and 2-4 parts of dendrobium.

On the other hand, the embodiment of the application provides a preparation method of the scar-removing traditional Chinese medicine composition, which is characterized by comprising the following steps:

step A: weighing herba Scutellariae Barbatae, herba seu radix Cirsii Japonici, rhizoma Helminthostachydis Zeylanicae, radix astragali, ginseng radix, radix Angelicae sinensis, glycyrrhrizae radix, rhizoma Bletillae, bombyx Batryticatus, rhizoma Polygonati Odorati, coptidis rhizoma, scutellariae radix and herba Dendrobii, cleaning, air drying, pulverizing, sieving, soaking in ethanol, decocting with water, and concentrating to obtain concentrated solution;

and B: and adding an auxiliary agent into the concentrated solution, and uniformly stirring to obtain the paste traditional Chinese medicine composition.

Compared with the prior art, the embodiment of the application has at least the following advantages or beneficial effects:

1. the embodiment of the application provides a scar-removing traditional Chinese medicine composition which is wide in raw material source, low in price and easy to obtain, and the raw materials have the effects of clearing heat and removing toxicity, promoting blood circulation to remove blood stasis, and dissolving lumps and dissipating stagnation under the synergistic effect, can remove various scars, has no toxic or side effect and no stimulation to skin, has the effects of protecting skin and resisting bacteria, and can achieve the effects of moistening and nourishing.

2. The embodiment of the application provides a preparation method of a scar-removing traditional Chinese medicine composition, which is simple and convenient for mass production, can greatly extract effective components from Chinese herbal medicines, is prepared into a paste shape, is convenient to apply and carry, and has a good treatment effect on scars.

Detailed Description

In order to make the objects, technical solutions and advantages of the embodiments of the present application clearer, the technical solutions in the embodiments of the present application will be clearly and completely described below. The examples, in which specific conditions are not specified, were conducted under conventional conditions or conditions recommended by the manufacturer. The reagents or instruments used are conventional products which are not indicated by manufacturers and are commercially available.

First, the embodiment of the application provides a scar-removing traditional Chinese medicine composition which comprises the following raw materials in parts by weight:

3-6 parts of sculellaria barbata, 1-2 parts of circium japonicum, 1-2 parts of paris polyphylla, 3-6 parts of astragalus membranaceus, 1-2 parts of ginseng, 2-4 parts of angelica sinensis, 1-2 parts of liquorice, 2-4 parts of bletilla striata, 2-4 parts of white muscardine silkworm, 2-4 parts of polygonatum odoratum, 1-2 parts of coptis chinensis, 1-2 parts of radix scutellariae and 2-4 parts of dendrobe.

In some embodiments of the present application, the following raw materials are included in parts by weight:

3 parts of barbed skullcap herb, 1 part of Japanese thistle herb, 1 part of paris polyphylla, 3 parts of astragalus root, 1 part of ginseng, 2 parts of angelica, 1 part of liquorice, 2 parts of bletilla striata, 2 parts of white muscardine silkworm, 2 parts of fragrant solomonseal rhizome, 1 part of coptis root, 1 part of radix scutellariae and 2 parts of dendrobium.

Barbat skullcap, distinguished name: the stringy verbena, thin scutellaria, toothbrush grass, herba hyperici japonici, baikal skullcap, hanxin grass are perennial herbs of scutellaria of the family labiatae. The stem is upright, and the plant height can reach 55 cm; the leaves have short or nearly no stem, and the leaves have a triangular oval shape or an oval shape and are needle-shaped, sometimes oval. The flower grows in the axils of the leaves at the upper parts of stems or branches, and the length of the stems of the flowers is 4-11 cm; the pedicel is 1-2 mm long and is slightly soft. The flowering time of the calyx is about 2 mm, the outer part of the calyx is slightly hairy along the pulse, and the edge of the calyx is provided with short marginal hair; the corolla is purple blue, the length is 9-13 mm, the external skin is short and the hair is soft, and the internal throat is sparse and the hair is soft; the flower and fruit period is 4-7 months. The whole herb is used as a medicine and has the functions of clearing away heat and toxic materials, promoting blood circulation to remove blood stasis, relieving swelling and pain, resisting cancer and the like. Is cold in nature and sour in taste, and contains various vitamins, trace elements, amino acids and other components. Has the effects of cooling blood, removing toxic substances, removing blood stasis, relieving pain, relieving swelling, clearing heat and promoting diuresis.

Circium japonicum, the name of Chinese medicine. Is dried aerial part of Cirsium japonicum of Compositae. Harvesting aerial parts when flowers bloom in summer and autumn, removing impurities, and drying in the sun. The processing method comprises the following steps: removing impurities, washing with water or moistening, cutting, and drying. Property and taste: sweet, bitter and cool. It enters heart and liver meridians. Has the effects of cooling blood, stopping bleeding, removing blood stasis and relieving swelling. The main indications are as follows: epistaxis, hematemesis, hematuria, hematochezia, metrorrhagia and metrostaxis, traumatic hemorrhage, carbuncle, swelling and sore. The compendium of materia Medica records: take Yun Jiu Shi, sheng Jian, jiu and urinate for any time. For further aversion to sores, scabies and tinea, it is ground with salt (Da Ming).

Rhizoma Helminthostachydis Zeylanicae is a plant of Paris of Liliaceae. Another name is paris rhizome, chi's fallow, dutchmanspipe root, whole fallow, paris polyphylla, white euphorbia, paris polyphylla, piper hancei, kyuandha, mandarin duck, boughs twig and flower head, hemsleya chinensis, hemsleya amabilis, paris polyphylla, gynura pseudochinensis, tusanchi, and also named schefflera arboricola. The method is characterized in that a circle of rotaryleaves are provided with a flower, the shape of the flower is like that of the leaf, the flower can be divided into two parts, namely an outer flower and an inner flower, the outer flower is similar to the leaf and has about 6 pieces, the inner flower has about 8 pieces, phyllotaria of seven-leaf and one-flower belongs to rotaryleaves, the number of the pieces is individual difference, and the seven-leaf is only named from 4 pieces to 14 pieces.

Astragalus membranaceus, a qi-invigorating drug, is the dried root of Astragalus membranaceus bge or Astragalus membranaceus bge of the family Brachypodaceae. The herb is sweet in property and slightly cold in nature, and enters spleen and lung meridians. Astragalus root, radix astragali, sweet in flavor and warm in nature, tonifies qi and warms up, and diffuses with the spleen; raw material is slightly warm, stir-baked with honey is warm in nature, enters spleen and lung meridians to strengthen body resistance and remove water pathogen. It is good at tonifying middle-jiao, promoting the production of clear yang, tonifying lung qi, reinforcing stomach and consolidating superficial resistance, treating spleen-lung qi deficiency, sinking of middle-jiao, qi failing to control blood, spontaneous perspiration and night sweat, and also has the actions of supporting sore toxin, inducing diuresis to alleviate edema, and treating sore and abscess due to deficiency of qi and blood, edema due to qi deficiency, and dysuria. In addition, it can tonify qi, promote blood production, control blood, promote fluid production, activate stagnancy, treat blood deficiency and sallow complexion, metrorrhagia and metrostaxis due to qi failing to control blood, diabetes due to qi and fluid deficiency, arthralgia and numbness due to qi deficiency and blood stagnation, hemiplegia, etc.

Ginseng is a perennial herb of the genus Panax of the family Araliaceae. Ginseng is sweet, slightly bitter and warm in flavor, and enters spleen, lung, heart and kidney meridians. Ginseng, sweet in flavor and warm in nature, slightly bitter in flavor and not leaking out, is a key herb for tonifying qi and strengthening body. It is good at invigorating primordial qi and treating qi deficiency; it is also good at tonifying spleen and lung qi, and indicated for spleen and lung qi deficiency; it also has effects in invigorating qi, promoting salivation, tranquilizing mind, improving intelligence, and treating thirst due to body fluid consumption, diabetes, uneasiness, palpitation, and amnesia. Mainly contains panaxadiol, panaxatriol and oleanolic acid ginsenoside, and also contains panaxan, polypeptide compounds, ester compounds, sesquiterpene alcohol compounds, alkyne compounds, amino acids, organic acids, alkaloids, vitamin flavonoids, volatile oil, trace elements and other components, and has the effects of invigorating primordial qi, restoring pulse, relieving depletion, invigorating spleen, benefiting lung, promoting fluid production, nourishing blood, tranquilizing mind and improving intelligence.

Angelica sinensis, a Chinese medicinal material, is a blood-tonifying drug, which is the dried root of Angelica sinensis (oliv.) Diels of Umbelliferae. Dang Gui is sweet, pungent and warm in flavor, and enters liver, heart and spleen meridians. Dang Gui is sweet in flavor and good in moistening property, pungent and warm in property and moving in the dispersing direction, it enters liver and heart meridians, and also enters spleen meridian. It excels in tonifying blood, activating blood, regulating menstruation, alleviating pain, moistening intestines, relaxing bowels, and dispelling cold, so it is suitable for blood deficiency and blood stasis with cold syndrome accompanied by constipation due to intestinal dryness, and it is not only the key herb for regulating menstruation in gynecology, but also the good herb for tonifying blood in internal medicine, and it is also commonly used in surgery and traumatology to relieve swelling and cure wound. Mainly contains volatile oil such as ligustilide, angelone, schizonepeta phenol, n-butene furan lactone, verbenone, safrole and the like, organic acid components such as ferulic acid, vanillic acid, nicotinic acid, succinic acid and the like, and also contains components such as angelica polysaccharide, amino acid, vitamin A and the like.

The Glycyrrhrizae radix is dried root and rhizome of Glycyrrhiza uralensis Fisch, glycyrrhiza inflata Bat or Glycyrrhiza glabra L of Leguminosae. Licorice root, radix Glycyrrhizae is sweet and neutral in nature and enters heart, lung, spleen and stomach meridians. Licorice root, radix Glycyrrhizae, sweet in flavor, mild in nature, cool in nature, warm in nature, enters the spleen and lung meridians, and also enters the stomach and heart meridians. Has effects of invigorating qi, strengthening middle warmer, relieving spasm, relieving pain, relieving drug property, eliminating phlegm, relieving cough, and removing toxic substance. Moxibustion has strong qi tonifying and acute and moderate effects; unprocessed can purge fire and remove toxicity. The product contains triterpenoid saponins and flavonoids.

Bletilla striata is a crude herb of the genus bletilla, family Orchidaceae. The plant height can reach 60 cm. Pseudobulb oblate spheroid shape, rich in viscosity. Strong and stiff stem. The blade is long and narrow and round or is needle-shaped, and the base part is narrowed to form a sheath and embrace the stem. The inflorescence has flowers, the buds are long and round and are in a needle shape, and the flowers usually wither when flowering; large, purple or pink; the sepals and the petals are nearly equal in length, long and narrow and round, and the petals are slightly wider than the sepals; the labial petals are slightly shorter than the sepals and the petals, are inverted oval, are white with purplish red and have purple veins; extending from the base to the top of the median lobe, the cylindrical core is narrow-finned and slightly bowed. Blooming in 4-5 months. Nature, flavor and meridian tropism: bitter, sweet, astringent and slightly cold. Enters liver, lung and stomach meridians. The efficacy is as follows: astringe to stop bleeding, resolve swelling and promote tissue regeneration.

Bombyx Batryticatus, alternative name: bombyx Batryticatus and Bombyx Batryticatus are dry whole silkworm from Bombyx mori (Bombycidae) infected with Beauveria bassiana. Cylindrical, and is bent and shrunk. The length is about 2-5 cm, and the diameter is 4-7 mm. The surface is grey white or light brown, and is mostly frosted white. The head, foot and joints are clear and distinct. The body is often entangled with clusters of silk. Head yellow brown, round-like. The feet 8 pairs are in a protruding shape. Hard and brittle, easy to break; the cross section is flat, the color is brown and black, the color is more bright, the outer layer is white and powdery, and 4 brown bright rings are arranged in the inner layer. Slightly rotten odor and slightly salty taste. The better one is that the strips are straight, fat, strong, white and have smooth cross section. In addition, beauveria bassiana is inoculated on silkworm pupa to cause disease and become the stiff silkworm, and can be used for medicine replacement of Bombyx Batryticatus. Bombyx Batryticatus is pungent, salty and mild in nature. Meridian tropism: enter liver, lung and stomach meridians. Dispel wind, relieve spasm, resolve phlegm and dissipate nodulation. It is indicated for wind stroke with aphonia, fright epilepsy, headache and laryngeal wind. Sore throat, scrofula and tuberculosis. Urticaria, erysipelas, mastitis.

Rhizoma Polygonati Odorati is a plant of Polygonatum of Liliaceae. Yuzhu is sweet in nature and slightly cold in flavor. It enters lung and stomach meridians. Yuzhu is soft, moist, sweet and tonic, and mild but slightly mild. Entering lung meridian, it can nourish lung yin, moisten lung and relieve cough; entering stomach meridian, it can nourish stomach yin to produce fluid and quench thirst. The ancient name of fragrant solomonseal rhizome, is not greasy and astringes pathogens, and can be combined with exterior-releasing herbs to achieve the effects of nourishing yin and relieving exterior syndrome. Rhizoma Polygonati Odorati is used as medicine with dry rhizome, has sweet taste and slightly cold nature, has effects of nourishing yin, moistening dryness, promoting fluid production, and quenching thirst, and can be used for treating yin injury of lung and stomach, cough due to dryness-heat, dry throat, thirst, internal heat, and diabetes. Yuzhu is also commonly processed into decoction pieces, health foods, health beverages, beauty cosmetics, and the like.

Huang Lian is bitter in property and taste and cold in nature. It enters heart, spleen, stomach, liver, gallbladder and large intestine meridians. Huang Lian is bitter and cold, clear and dry, and purge and descend pure yin, mainly entering heart meridian, stomach and spleen meridians, and liver, gallbladder and large intestine meridians. It can clear heat and purge fire, dry dampness, remove damp-heat toxin, so it is the essential herb for damp-heat and fire toxin, and widely indicated for damp-heat and fire toxin syndrome. Compared with Huang Qin, it has stronger actions of clearing heat and drying dampness, and is mainly used for clearing heat from heart and stomach, and removing damp-heat from middle energizer. The product contains isoquinoline alkaloids such as berberine, coptisine, jateorhizine, palmatine, african tetrandrine, columbine, and epiberberine. Also contains obacunone, phellodendrolidone, ferulic acid, chlorogenic acid, etc., and has effects of clearing heat, eliminating dampness, purging pathogenic fire, and removing toxic substance.

Scutellariae radix, the name of Chinese medicine. Herba Camelliae Japonicae root and radix seu folium Elsholtziae Pendulifoliae are perennial herbaceous plants of Scutellaria of Labiatae; fleshy rhizome is fat, leaf is hard and paper, the shape is from needle to linear, the general inflorescence is terminal on stem and branch, the corolla is purple, mauve to blue, the filament is flat, the style is slender, the flower disc is annular, the ovary is brown, the small nut is egg-shaped, the period of flower and fruit is 7-9 months. The scutellaria is grown on the sunny grass slope and has the altitude of 60-1300 (1700-2000) meters. The plants can be planted in the fields of Heilongjiang, liaoning, inner Mongolia, hebei, henan, gansu, shaanxi, shanxi, shandong, sichuan and the like, and in most provinces in the North of China. It is bitter in taste and cold in nature, and has effects of clearing heat and eliminating dampness, purging fire and removing toxic substance, stopping bleeding, preventing miscarriage, etc. It can be used for treating epidemic febrile disease, upper respiratory infection, cough due to lung heat, yellow gallbladder due to damp-heat, pneumonia, dysentery, hemoptysis, conjunctival congestion, fetal irritability, hypertension, carbuncle, furuncle, and sore. The clinical antibacterial property of scutellaria root is better than that of coptis root, and it does not produce drug resistance.

Dendrobium nobile is a deficiency-reinforcing drug, which is a cultivated product of Dendrobium nobile, dendrobium huoshanense, dendrobium chrysotoxum or Dendrobium fimbriatum belonging to Orchidaceae and a fresh or dry stem of a similar species of plants belonging to the same genus. Dendrobe is sweet in nature and slightly cold in nature. It enters stomach and kidney meridians. Dendrobium nobile is sweet in flavor and capable of nourishing and clearing heat and purging with slight cold, so it is indicated for clearing and nourishing. Entering stomach meridian, it can nourish stomach yin and promote the production of body fluid, and treat thirst due to deficiency of body fluid or stomach yin; entering kidney meridian, it can nourish kidney yin and clear deficiency heat, so it is indicated for deficiency-type deficiency-heat. In addition, it can also improve eyesight and strengthen waist by nourishing yin and clearing heat. Has stronger drug efficacy when being used fresh.

The raw materials of the invention have wide sources, are cheap and easy to obtain, have reasonable compatibility and synergistic effect, have the effects of clearing away heat and toxic material, promoting blood circulation by removing blood stasis, relieving distension and fullness and dissipating stagnation, can eliminate various scars and have wide application.

In some embodiments of the present application, an adjuvant is also included. The effect of the auxiliary agent can make the traditional Chinese medicine composition more stable, is more beneficial to the absorption of the medicine and improves the medicine effect.

In some embodiments of the present application, the adjuvant comprises one or more of propolis, sesame oil, pearl powder, sodium hyaluronate, vitamin C, glycerol, and glycerol monostearate.

In some embodiments of the present application, the formulation of the Chinese medicinal composition is an ointment. The ointment is convenient to act on scar, is convenient to smear and is more convenient to use.

Secondly, the embodiment of the application provides a preparation method of the scar-removing traditional Chinese medicine composition, which comprises the following steps:

In some embodiments of the present application, in step a, the particle size after pulverization is 80-120 mesh. When the particles with smaller particle size are crushed to be convenient for soaking, the extraction efficiency of the effective components is higher.

In some embodiments of the present application, the soaking time in step a is 4-6h. The soaking time is too short, the effective components can not be completely extracted, and the medicinal materials are wasted.

In some embodiments of the present application, in step a, the decoction time is 20-30min.

In some embodiments of the present application, in step a, the volume ratio of alcohol to water is 1: (2-5).

The features and properties of the present application are described in further detail below with reference to examples.

Example 1

The embodiment of the application provides a scar-removing traditional Chinese medicine composition which comprises the following raw materials in parts by weight:

4g of barbed skullcap herb, 4g of Japanese thistle herb, 1g of paris polyphylla, 5g of astragalus, 2g of ginseng, 3g of angelica, 1g of liquorice, 3g of bletilla striata, 4g of white muscardine silkworm, 3g of polygonatum odoratum, 2g of coptis chinensis, 1g of radix scutellariae and 3g of dendrobium.

The embodiment of the application provides a preparation method of a scar-removing traditional Chinese medicine composition, which comprises the following steps:

step A: weighing herba Scutellariae Barbatae, herba seu radix Cirsii Japonici, rhizoma Helminthostachydis Zeylanicae, radix astragali, ginseng radix, radix Angelicae sinensis, glycyrrhrizae radix, rhizoma Bletillae, bombyx Batryticatus, rhizoma Polygonati Odorati, coptidis rhizoma, scutellariae radix and herba Dendrobii, cleaning, air drying, pulverizing to particle size of 100 mesh, sieving, soaking in alcohol for 5 hr, decocting with water for 25min, and concentrating to obtain concentrated solution;

In this embodiment, the auxiliary agents are propolis, pearl powder, and sodium hyaluronate.

In this example, the volume ratio of alcohol to water was 1:4.

example 2

3g of barbed skullcap herb, 1g of Japanese thistle herb, 1g of paris polyphylla, 3g of astragalus, 1g of ginseng, 2g of angelica, 1g of liquorice, 2g of bletilla striata, 2g of white muscardine silkworm, 2g of polygonatum odoratum, 1g of coptis chinensis, 1g of radix scutellariae and 2g of dendrobium.

step A: weighing herba Scutellariae Barbatae, herba seu radix Cirsii Japonici, rhizoma Helminthostachydis Zeylanicae, radix astragali, ginseng radix, radix Angelicae sinensis, glycyrrhrizae radix, rhizoma Bletillae, bombyx Batryticatus, rhizoma Polygonati Odorati, coptidis rhizoma, scutellariae radix and herba Dendrobii, cleaning, air drying, pulverizing to particle size of 80 mesh, sieving, soaking in alcohol for 4h, decocting with water for 20min, and concentrating to obtain concentrated solution;

In this embodiment, the auxiliary agents are propolis, sesame oil, and pearl powder.

In this example, the volume ratio of alcohol to water was 1:2.

example 3

6g of barbed skullcap herb, 2g of Japanese thistle herb, 2g of paris polyphylla, 6g of astragalus root, 2g of ginseng, 4g of angelica, 2g of liquorice, 4g of bletilla striata, 4g of white muscardine silkworm, 4g of fragrant solomonseal rhizome, 2g of coptis root, 2g of radix scutellariae and 4g of dendrobium.

step A: weighing herba Scutellariae Barbatae, herba seu radix Cirsii Japonici, rhizoma Helminthostachydis Zeylanicae, radix astragali, ginseng radix, radix Angelicae sinensis, glycyrrhrizae radix, rhizoma Bletillae, bombyx Batryticatus, rhizoma Polygonati Odorati, coptidis rhizoma, scutellariae radix and herba Dendrobii, cleaning, air drying, pulverizing to particle size of 120 mesh, sieving, soaking in alcohol for 6h, decocting in water for 30min, and concentrating to obtain concentrated solution;

In this embodiment, the adjuvants are propolis, vitamin C, and glycerin.

In this example, the volume ratio of alcohol to water was 1:3.

example 4

30g of sculellaria barbata, 10g of Japanese thistle herb, 15g of paris polyphylla, 30g of astragalus membranaceus, 15g of ginseng, 25g of angelica, 15g of liquorice, 20g of bletilla striata, 30g of white muscardine silkworm, 30g of polygonatum odoratum, 20g of coptis chinensis, 20g of radix scutellariae and 25g of dendrobium.

step A: weighing herba Scutellariae Barbatae, herba seu radix Cirsii Japonici, rhizoma Helminthostachydis Zeylanicae, radix astragali, ginseng radix, radix Angelicae sinensis, glycyrrhrizae radix, rhizoma Bletillae, bombyx Batryticatus, rhizoma Polygonati Odorati, coptidis rhizoma, scutellariae radix and herba Dendrobii, cleaning, air drying, pulverizing to particle size of 110 mesh, sieving, soaking in alcohol for 6h, decocting in water for 30min, and concentrating to obtain concentrated solution;

In this embodiment, the auxiliary agents include propolis, pearl powder, sodium hyaluronate, vitamin C, and glycerin.

In this example, the volume ratio of alcohol to water was 1:5.

comparative example

In this comparative example, a commercial Bio-Oil hundred Lolo Oil was purchased.

Examples of the experiments

1. And (3) safety test:

the ointment Chinese medicinal compositions of examples 1 to 4 were mixed to obtain a mixed ointment. The obtained mixed paste is used as a test medicament, 160 mice with the weight of 18-20g in each half of male and female are used as test animals, the test animals are divided into 4 groups, medicaments with different concentrations are respectively gavaged, the concentrations are respectively 10mg/ml, 40mg/ml, 60mg/ml and 80mg/ml, the administration volumes are respectively 40ml/kg, the administration is carried out on the mice by gavage for 3 times in one day, and the cumulative gavage administration volume is 100ml/kg. No obvious toxic reaction is observed after 7 days. After dissection, the main organs have no obvious abnormality through visual observation.

Taking male and female half mice weighing 18-20g as test animals, dividing into two groups with 100 animals, and performing long-term toxicity test, wherein the administration concentration of one group is 60mg/ml, and the administration volume is 40ml/kg; the other group is distilled water with the same volume, and is continuously drenched for 3 months for long-term toxicity test. The long-term toxicity test result shows that the general behavior and activity and weight increase of the test animal are normal, the hematology index, the liver and kidney function and the organ coefficient of the main organ are not obviously influenced, and the main organ is not obviously pathologically damaged, thereby indicating that the medicament has no toxicity.

2. Clinical tests were conducted on the ointment Chinese medicinal compositions obtained in examples 1 to 4 and comparative examples, and the results were as follows:

subject selection: 200 patients with scars were selected, 102 in male patients and 98 in female patients. All patients were randomly divided into 5 groups, i.e., experiment group 1, experiment group 2, experiment group 3, experiment group 4, and experiment group 5, 40 cases each, and patients in experiment groups 1 to 4 used the ointment Chinese medicinal compositions prepared in examples 1 to 4, and patients in experiment group 5 used Bio-Oil bailo Oil. Five groups of patients have no obvious difference in age, disease conditions and the like and are comparable.

The taking method comprises the following steps: the ointment Chinese medicinal composition obtained in the experimental groups 1 to 4 is uniformly smeared on scars twice a morning and a night for 30 days. Experimental group 5 applied Bio-Oil balo Oil evenly to the scar twice a night and a morning for 30 days.

Criteria for judging therapeutic effects

And (3) curing: the scar symptom of the patient disappears, and the body surface returns to normal;

the method has the following advantages: the scar symptoms of the patient gradually reduce or the symptoms disappear;

and (4) invalidation: scar symptoms do not improve;

total effective rate = (number of cure cases + number of effective cases)/number of cases.

The results are shown in table 1:

TABLE 1 treatment results of experimental groups 1-5

According to the experimental data, the ointment traditional Chinese medicine composition provided by the invention has a good treatment effect on scars, and the treatment effect is caused by the Bio-Oil dolo Oil purchased on the market. The main components of the Chinese medicinal composition are Chinese medicinal herb components, so the Chinese medicinal composition has no toxic or side effect, reasonable compatibility of the raw materials, easy obtainment and practical value of application and popularization.

In summary, the embodiment of the application provides a scar-removing traditional Chinese medicine composition, which has wide raw material sources, is cheap and easy to obtain, has the effects of clearing heat and removing toxicity, promoting blood circulation to remove blood stasis, and dissolving lumps and dissipating stagnation by the synergistic effect of the raw materials, can remove various scars, has no toxic or side effect and no stimulation to skin, has the effects of protecting skin and resisting bacteria, and can achieve the effects of moistening and nourishing.

The embodiments described above are some, but not all embodiments of the present application. The detailed description of the embodiments of the present application is not intended to limit the scope of the claimed application, but is merely representative of selected embodiments of the application. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present application.

Claims

1. The scar-removing traditional Chinese medicine composition is characterized by comprising the following raw materials in parts by weight:

2. The scar-removing traditional Chinese medicine composition according to claim 1, which is characterized by comprising the following raw materials in parts by weight:

3 parts of barbed skullcap herb, 1 part of Japanese thistle herb, 1 part of paris polyphylla, 3 parts of astragalus root, 1 part of ginseng, 2 parts of angelica, 1 part of liquorice, 2 parts of bletilla striata, 2 parts of white muscardine silkworm, 2 parts of polygonatum odoratum, 1 part of coptis chinensis, 1 part of radix scutellariae and 2 parts of dendrobium.

3. The scar-removing traditional Chinese medicine composition according to claim 1, further comprising an auxiliary agent.

4. The scar-removing traditional Chinese medicine composition according to claim 3, wherein the auxiliary agent comprises one or more of propolis, sesame oil, pearl powder, sodium hyaluronate, vitamin C, glycerol and glyceryl monostearate.

5. The scar-removing traditional Chinese medicine composition according to claim 1, wherein the traditional Chinese medicine composition is in a form of ointment.

6. A method for preparing the scar-removing traditional Chinese medicine composition according to any one of claims 1 to 5, which comprises the following steps:

step A: weighing herba Scutellariae Barbatae, herba seu radix Cirsii Japonici, rhizoma Helminthostachydis Zeylanicae, radix astragali, ginseng radix, radix Angelicae sinensis, glycyrrhrizae radix, rhizoma Bletillae, bombyx Batryticatus, rhizoma Polygonati Odorati, coptidis rhizoma, scutellariae radix and herba Dendrobii, cleaning, air drying, pulverizing, sieving, soaking in alcohol, decocting with water, and concentrating to obtain concentrated solution;

7. The preparation method of the scar-removing traditional Chinese medicine composition according to claim 6, wherein in the step A, the particle size after crushing is 80-120 meshes.

8. The preparation method of the scar-removing traditional Chinese medicine composition according to claim 6, wherein in the step A, the soaking time is 4-6h.

9. The preparation method of the scar-removing traditional Chinese medicine composition according to claim 6, wherein in the step A, the decoction time is 20-30min.

10. The preparation method of the scar-removing traditional Chinese medicine composition according to claim 6, wherein in the step A, the volume ratio of alcohol to water is 1: (2-5).