CN107375614A - Scar of dispelling patch and preparation method thereof - Google Patents

Scar of dispelling patch and preparation method thereof Download PDF

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Publication number
CN107375614A
CN107375614A CN201710547216.3A CN201710547216A CN107375614A CN 107375614 A CN107375614 A CN 107375614A CN 201710547216 A CN201710547216 A CN 201710547216A CN 107375614 A CN107375614 A CN 107375614A
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Prior art keywords
parts
portions
scar
dispelling
root
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CN201710547216.3A
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Chinese (zh)
Inventor
万家林
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Hefei Fengruilong Biological Technology Co Ltd
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Hefei Fengruilong Biological Technology Co Ltd
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Priority to CN201710547216.3A priority Critical patent/CN107375614A/en
Publication of CN107375614A publication Critical patent/CN107375614A/en
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/896—Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/365—Lactones
    • A61K31/375—Ascorbic acid, i.e. vitamin C; Salts thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/232—Angelica
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/237—Notopterygium
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/42—Cucurbitaceae (Cucumber family)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/63—Oleaceae (Olive family), e.g. jasmine, lilac or ash tree
    • A61K36/634—Forsythia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
    • A61K36/738—Rosa (rose)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/75—Rutaceae (Rue family)
    • A61K36/756—Phellodendron, e.g. corktree
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/80—Scrophulariaceae (Figwort family)
    • A61K36/804—Rehmannia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/886—Aloeaceae (Aloe family), e.g. aloe vera
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/46—Ingredients of undetermined constitution or reaction products thereof, e.g. skin, bone, milk, cotton fibre, eggshell, oxgall or plant extracts
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30—Extraction of the material
    • A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30—Extraction of the material
    • A61K2236/39—Complex extraction schemes, e.g. fractionation or repeated extraction steps
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/50—Methods involving additional extraction steps
    • A61K2236/51—Concentration or drying of the extract, e.g. Lyophilisation, freeze-drying or spray-drying

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Abstract

The invention discloses one kind dispel scar patch and preparation method thereof, this dispel scar patch include tack coat and the medicine layer being arranged on tack coat, medicine layer includes the raw material of following parts by weight：5~13 parts of carrot meals, 15~25 portions of mung beans, 8~14 portions of aloes, 10~15 portions of roses, 7~12 portions of lavenders, 5~10 parts of cultivated lands, 5~9 portions of notopterygium roots, 2~4 parts of waxgourd peels, 3~5 parts of capsules of weeping forsythia, 4~7 portions of golden cypresses, 2~4 parts of roots of Dahurain angelica, 5~10 parts of ursolic acid, 4~5 parts of vitamin Bs.Each raw material sources are extensive in the present invention, inexpensive easily to take, and each raw material synergy plays clearing heat and detoxicating, promoting blood circulation and removing blood stasis, dissolving lump and resolving mass effect, various scars can be eliminated, have no toxic side effect non-stimulated to skin, and also there is the effect of skin care, antibacterial, play a part of moist foster skin.

Description

Scar of dispelling patch and preparation method thereof
Technical field
Scar field is repaired the present invention relates to treatment, more particularly to one kind is dispelled scar patch and preparation method thereof.
Background technology
Scar refers to the mode of appearance of caused normal skin tissue after various wounds and the change of histopathology It is referred to as.It is a kind of normal, inevitable physiological reaction during wound or surface of a wound normal healing after human body wound, It is the inevitable outcome of wound healing process.The essence of scar be it is a kind of do not possess normal skin tissue's structure and physiological function, Normal structure vigor, abnormal, unsound tissue are lost, destroys body surface U.S..Treat the medicine of scar on the market at present A lot, but weak curative effect, cost are high.
The content of the invention
In view of this, dispelled scar patch and preparation method thereof it is an object of the invention to provide one kind, good effect, cost is low.
To achieve these goals, the invention provides following technical scheme：
One kind is dispelled scar patch, including tack coat and the medicine layer that is arranged on the tack coat, the medicine layer include with The raw material of lower parts by weight：
Preferably, the medicine layer includes the raw material of following parts by weight：
Preferably, in addition to auxiliary material, the parts by weight of the auxiliary material are 150~200 parts.
Preferably, the auxiliary material includes Sodium Hyaluronate, glycerine, pearl powder and single stearic acid glycerine lipoprotein.
Present invention also offers a kind of above-mentioned preparation method for scar patch of dispelling, comprise the following steps：
Carrot meal, mung bean, aloe, rose, lavender, cultivated land, notopterygium root, waxgourd peel, the capsule of weeping forsythia, golden cypress, the root of Dahurain angelica are crushed After add medicine decocting tank, and add water for the first time, after stirring, soak 3~5h；Second of the addition water into the medicine decocting tank, Boil rear slow fire and endure 3~5h, filter, obtain the first filtrate；Add water for the third time into the filter residue being filtrated to get, boil rear slow fire and endure 1~2h, filtering, obtains the second filtrate；First filtrate and second filtrate are merged, concentration, to the material after concentration Middle addition ursolic acid and vitamin B, is coated onto on cohesive carrier after well mixed, and at 40~50 DEG C baking 3~ 5min obtains scar patch of dispelling.
Preferably, in addition into the material after concentration auxiliary material is added.
Preferably, the first time adds the dosage of water to be the carrot meal, the mung bean, the aloe, the rose Colored, described lavender, the cultivated land, the notopterygium root, the waxgourd peel, the capsule of weeping forsythia, the golden cypress, the 2~3 of the root of Dahurain angelica Times；Described second plus water dosage be the carrot meal, the mung bean, the aloe, the rose, the lavender, The cultivated land, the notopterygium root, the waxgourd peel, the capsule of weeping forsythia, the golden cypress, 4~6 times of the root of Dahurain angelica total amount；Described 3rd The dosage of secondary feedwater is the carrot meal, the mung bean, the aloe, the rose, the lavender, the cultivated land, institute State notopterygium root, the waxgourd peel, the capsule of weeping forsythia, the golden cypress, 2~3 times of the root of Dahurain angelica total amount.
One kind provided by the invention dispel scar patch and preparation method thereof, this dispel scar patch include tack coat and be arranged on tack coat Medicine layer, medicine layer includes the raw material of following parts by weight：5~13 parts of carrot meals, 15~25 portions of mung beans, 8~14 portions of reeds Luxuriant growth, 10~15 portions of roses, 7~12 portions of lavenders, 5~10 parts of cultivated lands, 5~9 portions of notopterygium roots, 2~4 parts of waxgourd peels, 3~5 parts of companies Stick up, 4~7 portions of golden cypresses, 2~4 parts of roots of Dahurain angelica, 5~10 parts of ursolic acid, 4~5 parts of vitamin Bs.Each raw material sources are extensive in the present invention, Inexpensive easily to take, each raw material synergy plays clearing heat and detoxicating, promoting blood circulation and removing blood stasis, dissolving lump and resolving mass effect, can eliminate various scars, Have no toxic side effect non-stimulated to skin, and also there is the effect of skin care, antibacterial, play a part of moist foster skin.
Embodiment
In order to further appreciate that the present invention, the preferred embodiments of the invention are described with reference to embodiment, but It is it should be appreciated that these descriptions are simply for further explanation the features and advantages of the present invention rather than to patent requirements of the present invention Limitation.
Dispelled scar patch, including tack coat and the medicine layer that is arranged on the tack coat the invention provides one kind, the medicine Nitride layer includes the raw material of following parts by weight：
In above-mentioned technical proposal, each raw material sources are extensive, inexpensive easily to take, and each raw material synergy plays clearing heat and detoxicating, living Blood stagnation resolvation, the effect of dissolving lump and resolving mass, can eliminate various scars, have no toxic side effect non-stimulated to skin, and also have skin care, resist The effect of bacterium, play a part of moist foster skin.
Carrot meal have foster skin dispel scar the effect of.In the present invention, the parts by weight of carrot meal are 5~13 parts；At this In the embodiment of invention, the parts by weight of carrot meal are 7~11 parts；In other embodiments, the parts by weight of carrot meal are 8 ~10 parts.
Mung bean has the function that antibacterial bacteriostatic, clearing heat and detoxicating, diuresis moisturizing.In the present invention, the parts by weight of mung bean are 15~25 parts；In an embodiment of the present invention, the parts by weight of mung bean are 17~23 parts；In other embodiments, the weight of mung bean It is 19~21 parts to measure number.
Aloe has the function that bactericidal antiphlogistic, removes free radical, improves the effect of blood circulation, acne-removing, skin-nourishing.In this hair In bright, the parts by weight of aloe are 8~14 parts；In an embodiment of the present invention, the parts by weight of aloe are 9~13 parts；At it In his embodiment, the parts by weight of aloe are 10~12 parts.
Rose can improve dry skin, recover skin elasticity, there is the effect of anti-ageing, smoothing wrinkle and moisturizing.In this hair In bright, the parts by weight of rose are 10~15 parts；In an embodiment of the present invention, the parts by weight of rose are 11~14 Part；In other embodiments, the parts by weight of rose are 12~13 parts.
Lavender has the function that scar.In the present invention, the parts by weight of lavender are 7~12 parts；In the present invention Embodiment in, the parts by weight of lavender are 8~11 parts；In other embodiments, the parts by weight of lavender are 9~10 Part.
Cultivated land, which can enrich blood, comforts sore, nutrition skin.In the present invention, the parts by weight of cultivated land are 5~10 parts；In the present invention Embodiment in, the parts by weight of cultivated land are 6~9 parts；In other embodiments, the parts by weight of cultivated land are 7~8 parts.
Notopterygium root can avoid pruitus.In the present invention, the parts by weight of notopterygium root are 5~9 parts；In the implementation of the present invention In example, the parts by weight of notopterygium root are 6~8 parts；In other embodiments, the parts by weight of notopterygium root are 6.5~7.5 parts.
Waxgourd peel can play a part of inducing diuresis to remove edema.In the present invention, the parts by weight of waxgourd peel are 2~4 parts；At this In the embodiment of invention, the parts by weight of waxgourd peel are 2.4~3.6 parts；In other embodiments, the parts by weight of waxgourd peel are 2.8~3.2 parts.
The capsule of weeping forsythia has heat-clearing, removing toxic substances, dissipating bind, the effect of detumescence.In the present invention, the parts by weight of the capsule of weeping forsythia are 3~5 parts； In an embodiment of the present invention, the parts by weight of the capsule of weeping forsythia are 3.4~4.6 parts；In other embodiments, the parts by weight of the capsule of weeping forsythia are 3.8~4.2 parts.
Golden cypress has a heat-clearing and damp-drying drug, purging intense heat, except steaming, the effect of detoxification sore treatment.In the present invention, the parts by weight of golden cypress are 4 ~7 parts；In an embodiment of the present invention, the parts by weight of golden cypress are 4.5~6.5 parts；In other embodiments, the weight of golden cypress Number is 5~6 parts.
The root of Dahurain angelica has apocenosis of invigorating blood circulation, the effect of myogenic pain relieving.In the present invention, the parts by weight of the root of Dahurain angelica are 2~4 parts； In embodiments of the invention, the parts by weight of the root of Dahurain angelica are 2.4~3.6 parts；In other embodiments, the parts by weight of the root of Dahurain angelica are 2.7~3.3 parts.
Ursolic acid has the function that calmness, anti-inflammatory, antibacterial, anti-diabetic, antiulcer.In the present invention, the weight of ursolic acid It is 5~10 parts to measure number；In an embodiment of the present invention, the parts by weight of ursolic acid are 6~9 parts；In other embodiments, bear The parts by weight of tartaric acid are 7~8 parts.
Vitamin B has the effect of beautifying face and moistering lotion.In the present invention, the parts by weight of vitamin B are 4~5 parts；In this hair In bright embodiment, the parts by weight of vitamin B are 4.2~4.8 parts；In other embodiments, the parts by weight of vitamin B are 4.4~4.6 parts.
In an embodiment of the present invention, in addition to auxiliary material, the parts by weight of auxiliary material are 150~200 parts.Wherein auxiliary material plus Enter to improve absorbability of the skin to scar ointment of dispelling, and the effect of the addition of auxiliary material can give full play to each raw material, it is thorough Bottom eliminates scar, additionally it is possible to plays a part of Glycerin.
In an embodiment of the present invention, auxiliary material includes Sodium Hyaluronate, glycerine, pearl powder, single stearic acid glycerine lipoprotein. In other embodiment, Sodium Hyaluronate, glycerine, pearl powder, the mass ratio of single stearic acid glycerine lipoprotein are (1~2)：(2~3)： (0.5~0.8)：(0.3~0.5).
Present invention also offers a kind of above-mentioned preparation method for scar patch of dispelling, comprise the following steps：
Carrot meal, mung bean, aloe, rose, lavender, cultivated land, notopterygium root, waxgourd peel, the capsule of weeping forsythia, golden cypress, the root of Dahurain angelica are crushed After add medicine decocting tank, and add water for the first time, after stirring, soak 3~5h；Second of the addition water into the medicine decocting tank, Boil rear slow fire and endure 3~5h, filter, obtain the first filtrate；Add water for the third time into the filter residue being filtrated to get, boil rear slow fire and endure 1~2h, filtering, obtains the second filtrate；First filtrate and second filtrate are merged, concentration, to the material after concentration Middle addition ursolic acid and vitamin B, is coated onto on cohesive carrier after well mixed, and at 40~50 DEG C baking 3~ 5min obtains scar patch of dispelling.
Wherein, carrot meal, mung bean, aloe, rose, lavender, cultivated land, notopterygium root, waxgourd peel, the capsule of weeping forsythia, golden cypress, the root of Dahurain angelica, Ursolic acid, vitamin B are same as above, will not be repeated here.
Above-mentioned technical proposal, first soaks to be cooked by slow fire again and enables to the drug effect of medicine best, so as to effectively disappear Except scar, and curative effect is stable, has no side effect, and cure rate is high.
In an embodiment of the present invention, in addition into the material after concentration auxiliary material is added.
In an embodiment of the present invention, for the first time plus water dosage be carrot meal, mung bean, aloe, rose, lavender, Cultivated land, notopterygium root, waxgourd peel, the capsule of weeping forsythia, golden cypress, 2~3 times of the root of Dahurain angelica；Second plus water dosage be carrot meal, mung bean, aloe, Rose, lavender, cultivated land, notopterygium root, waxgourd peel, the capsule of weeping forsythia, golden cypress, 4~6 times of root of Dahurain angelica total amount；The dosage of feedwater is for the third time Carrot meal, mung bean, aloe, rose, lavender, cultivated land, notopterygium root, waxgourd peel, the capsule of weeping forsythia, golden cypress, 2~3 times of root of Dahurain angelica total amount.
In order to further illustrate the present invention, scar patch and preparation method thereof provided by the invention of dispelling is entered with reference to embodiment Row describes in detail, but they can not be interpreted as into limiting the scope of the present invention.
Raw material used is commercially available in following examples.
Embodiment 1
Scar of dispelling pastes the raw material for including following parts by weight：
11 parts of carrot meals, 17 portions of mung beans, 12 portions of aloes, 13 portions of roses, 10 portions of lavenders, 10 parts of cultivated lands, 7.5 parts of Qiang Work, 2.8 parts of waxgourd peels, 3.4 parts of capsules of weeping forsythia, 5 portions of golden cypresses, 2.7 parts of roots of Dahurain angelica, 8 parts of ursolic acid, 3.7 parts of vitamin Cs, 4.6 parts of vitamins B, 32 parts of Sodium Hyaluronates, 96 parts of glycerine, 16 parts of pearl powders, 16 parts of single stearic acid glycerine lipoproteins.
The preparation method of scar of dispelling patch comprises the following steps：
Carrot meal, mung bean, aloe, rose, lavender, cultivated land, notopterygium root, waxgourd peel, the capsule of weeping forsythia, golden cypress, the root of Dahurain angelica are crushed After add medicine decocting tank, and add 188.8 parts of water, after stirring, soak 4h；566.4 parts of water are added into the medicine decocting tank, are boiled Slow fire endures 4h after boiling, filtering, obtains the first filtrate；Add 188.8 parts of water into the filter residue being filtrated to get, boil rear slow fire and endure 1.5h, filtering, obtains the second filtrate；First filtrate and second filtrate are merged, concentration, into the material after concentration Ursolic acid, vitamin B, auxiliary material are added, is coated onto after well mixed on cohesive carrier, and toasts 4min at 45 DEG C and produces To scar patch of dispelling.
Embodiment 2
Scar of dispelling pastes the raw material for including following parts by weight：
10 parts of carrot meals, 19 portions of mung beans, 13 portions of aloes, 11 portions of roses, 11 portions of lavenders, 9 parts of cultivated lands, 6 portions of notopterygium roots, 3.2 parts of waxgourd peels, 4.6 parts of capsules of weeping forsythia, 6 portions of golden cypresses, 2.4 parts of roots of Dahurain angelica, 5 parts of ursolic acid, 3 parts of vitamin Cs, 4.8 parts of vitamin Bs, 35.86 parts of Sodium Hyaluronates, 83.67 parts of glycerine, 16.43 parts of pearl powders, 14.04 parts of single stearic acid glycerine lipoproteins.
The preparation method of scar of dispelling patch comprises the following steps：
Carrot meal, mung bean, aloe, rose, lavender, cultivated land, notopterygium root, waxgourd peel, the capsule of weeping forsythia, golden cypress, the root of Dahurain angelica are crushed After add medicine decocting tank, and add 209.44 parts of water, after stirring, soak 3h；523.6 parts of water are added into the medicine decocting tank, Boil rear slow fire and endure 5h, filter, obtain the first filtrate；Add 209.44 parts of water into the filter residue being filtrated to get, boil rear slow fire and endure 1h, filtering, obtains the second filtrate；First filtrate and second filtrate are merged, concentration, added into the material after concentration Enter ursolic acid, vitamin B, auxiliary material, be coated onto after well mixed on cohesive carrier, and toast 5min at 40 DEG C and obtain Scar of dispelling is pasted.
Embodiment 3
Scar of dispelling pastes the raw material for including following parts by weight：
7 parts of carrot meals, 23 portions of mung beans, 9 portions of aloes, 15 portions of roses, 7 portions of lavenders, 8 parts of cultivated lands, 6.5 portions of notopterygium roots, 2.4 parts of waxgourd peels, 3.8 parts of capsules of weeping forsythia, 4 portions of golden cypresses, 3.6 parts of roots of Dahurain angelica, 10 parts of ursolic acid, 3.4 parts of vitamin Cs, 4 parts of vitamin Bs, 47.41 parts of Sodium Hyaluronates, 88.05 parts of glycerine, 20.32 parts of pearl powders, 14.22 parts of single stearic acid glycerine lipoproteins.
The preparation method of scar of dispelling patch comprises the following steps：
Carrot meal, mung bean, aloe, rose, lavender, cultivated land, notopterygium root, waxgourd peel, the capsule of weeping forsythia, golden cypress, the root of Dahurain angelica are crushed After add medicine decocting tank, and add 214.32 parts of water, after stirring, immersion 3；357.2 parts of water are added into the medicine decocting tank, are boiled Slow fire endures 3h after boiling, filtering, obtains the first filtrate；Add 267.9 parts of water into the filter residue being filtrated to get, boil rear slow fire and endure 1h, Filtering, obtains the second filtrate；First filtrate and second filtrate are merged, concentration, added into the material after concentration Ursolic acid, vitamin B, auxiliary material, it is coated onto after well mixed on cohesive carrier, and toasts 3min at 50 DEG C and dispelled Scar is pasted.
Embodiment 4
Scar of dispelling pastes the raw material for including following parts by weight：
8 parts of carrot meals, 21 portions of mung beans, 12 portions of aloes, 14 portions of roses, 8 portions of lavenders, 7 parts of cultivated lands, 8 parts of notopterygium roots, 3.6 Part waxgourd peel, 4.2 parts of capsules of weeping forsythia, 7 portions of golden cypresses, 2 parts of roots of Dahurain angelica, 6 parts of ursolic acid, 4.3 parts of vitamin Cs, 5 parts of vitamin Bs, 56.47 parts Sodium Hyaluronate, 84.71 parts of glycerine, 24.70 parts of pearl powders, 14.12 parts of single stearic acid glycerine lipoproteins.
The preparation method of scar of dispelling patch comprises the following steps：
Carrot meal, mung bean, aloe, rose, lavender, cultivated land, notopterygium root, waxgourd peel, the capsule of weeping forsythia, golden cypress, the root of Dahurain angelica are crushed After add medicine decocting tank, and add 246.48 parts of water, after stirring, soak 5h；426.6 parts of water are added into the medicine decocting tank, Boil rear slow fire and endure 4h, filter, obtain the first filtrate；Add 246.48 parts of water into the filter residue being filtrated to get, boil rear slow fire and endure 1h, filtering, obtains the second filtrate；First filtrate and second filtrate are merged, concentration, added into the material after concentration Enter ursolic acid, vitamin B, auxiliary material, be coated onto after well mixed on cohesive carrier, and toast 5min at 50 DEG C and obtain Scar of dispelling is pasted.
Embodiment 5
Scar of dispelling pastes the raw material for including following parts by weight：
5 parts of carrot meals, 25 portions of mung beans, 8 portions of aloes, 12 portions of roses, 9 portions of lavenders, 6 parts of cultivated lands, 9 portions of notopterygium roots, 2 parts Waxgourd peel, 3 parts of capsules of weeping forsythia, 4.5 portions of golden cypresses, 4 parts of roots of Dahurain angelica, 9 parts of ursolic acid, 4.5 parts of vitamin Cs, 4.2 parts of vitamin Bs, 67.72 parts Sodium Hyaluronate, 82.77 parts of glycerine, 28.22 parts of pearl powders, 11.29 parts of single stearic acid glycerine lipoproteins.
The preparation method of scar of dispelling patch comprises the following steps：
Carrot meal, mung bean, aloe, rose, lavender, cultivated land, notopterygium root, waxgourd peel, the capsule of weeping forsythia, golden cypress, the root of Dahurain angelica are crushed After add medicine decocting tank, and add 245 parts of water, after stirring, soak 5h；393.75 parts of water are added into the medicine decocting tank, are boiled Slow fire endures 3h after boiling, filtering, obtains the first filtrate；Add 245 parts of water into the filter residue being filtrated to get, boil rear slow fire and endure 2h, mistake Filter, obtains the second filtrate；First filtrate and second filtrate are merged, concentration, bear is added into the material after concentration Tartaric acid, vitamin B, auxiliary material, it is coated onto after well mixed on cohesive carrier, and toasts 3min at 40 DEG C and obtain scar of dispelling Patch.
Embodiment 6
Scar of dispelling pastes the raw material for including following parts by weight：
13 parts of carrot meals, 15 portions of mung beans, 14 portions of aloes, 10 portions of roses, 12 portions of lavenders, 5 parts of cultivated lands, 5 parts of notopterygium roots, 4 Part waxgourd peel, 5 parts of capsules of weeping forsythia, 6.5 portions of golden cypresses, 3.3 parts of roots of Dahurain angelica, 7 parts of ursolic acid, 5 parts of vitamin Cs, 4.4 parts of vitamin Bs, 77.67 Part Sodium Hyaluronate, 77.67 parts of glycerine, 31.07 parts of pearl powders, 13.59 parts of single stearic acid glycerine lipoproteins.
The preparation method of scar of dispelling patch comprises the following steps：
Carrot meal, mung bean, aloe, rose, lavender, cultivated land, notopterygium root, waxgourd peel, the capsule of weeping forsythia, golden cypress, the root of Dahurain angelica are crushed After add medicine decocting tank, and add 278.4 parts of water, after stirring, soak 5h；528.96 parts of water are added into the medicine decocting tank, Boil rear slow fire and endure 4h, filter, obtain the first filtrate；Add 222.72 parts of water into the filter residue being filtrated to get, boil rear slow fire and endure 1h, filtering, obtains the second filtrate；First filtrate and second filtrate are merged, concentration, added into the material after concentration Enter ursolic acid, vitamin B, auxiliary material, be coated onto after well mixed on cohesive carrier, and toast 3min at 45 DEG C and obtain Scar of dispelling is pasted.
Embodiment 7
Scar of dispelling pastes the raw material for including following parts by weight：
9 parts of carrot meals, 20 portions of mung beans, 11 portions of aloes, 12.5 portions of roses, 9.5 portions of lavenders, 7.5 parts of cultivated lands, 7 parts of Qiang Work, 3 parts of waxgourd peels, 4 parts of capsules of weeping forsythia, 5.5 portions of golden cypresses, 3 parts of roots of Dahurain angelica, 7.5 parts of ursolic acid, 4 parts of vitamin Cs, 4.5 parts of vitamin Bs, parts Sodium Hyaluronate, part glycerine, part pearl powder, part single stearic acid glycerine lipoprotein.
The preparation method of scar of dispelling patch comprises the following steps：
Carrot meal, mung bean, aloe, rose, lavender, cultivated land, notopterygium root, waxgourd peel, the capsule of weeping forsythia, golden cypress, the root of Dahurain angelica are crushed After add medicine decocting tank, and add 230 parts of water, after stirring, soak 4h；460 parts of water are added into the medicine decocting tank, after boiling Slow fire endures 4h, filtering, obtains the first filtrate；Add 230 parts of water into the filter residue being filtrated to get, boil rear slow fire and endure 1.5h, filter, Obtain the second filtrate；First filtrate and second filtrate are merged, concentration, black bearberry is added into the material after concentration Acid, vitamin B, auxiliary material, it is coated onto after well mixed on cohesive carrier, and toasts 4min at 45 DEG C and obtain scar of dispelling Patch.
First, safety testing：
The ointment that the scar of dispelling of Example 1~7 is sticked, mixing, obtains hybrid medicine.
It is dynamic by experiment of the small white mouse of body weight 18-20g male and female half and half using the hybrid medicine of above-mentioned gained as trial drug Thing, totally 210, be divided into 7 groups, respectively the medicine of gavage various concentrations, concentration be respectively 10mg/ml, 40mg/ml, 60mg/ml, 80mg/ml, 100mg/ml, administered volume are 40ml/kg, to gastric infusion in mouse one day 3 times, accumulate gastric infusion volume For 100ml/kg.Observation 7 days, have no overt toxicity reaction and the reaction of pawpaw enteron aisle.Through visually observing after dissection, main organs Non Apparent Abnormality.
The small white mouse of body weight 18-20g male and female half and half is experimental animal, totally 100, is divided into two groups, carries out long term toxicity examination Test, one group of administration concentration is 60mg/ml, administered volume 40ml/kg；Another group is isometric distilled water, continuously gavages 3 Individual month, carry out long term toxicity test.Long term toxicity test result shows that the general behavior activity of experimental animal and body weight increase are just Often, to hematological indices, the organ coefficient of hepatic and renal function and main organs is had no significant effect, and main organs are damaged without obvious pathology Wound, show medicine nontoxicity.
2nd, the preparation for obtaining embodiment 1~7 carries out clinical test, as a result as follows：
1st, subject selects：Select the scar patient in March, 2014~certain hospital accepts for medical treatment so far totally 800, wherein male Patient 402, female patient 398.
2nd, packet design：All patients are randomly divided into eight groups, respectively experimental group 1, experimental group 2, experimental group 3, experimental group 4th, experimental group 5, experimental group 6, experimental group 7 and control group, each 100, eight groups of patients are at age, the state of an illness etc. without significance difference It is different, there is comparativity.The scar of dispelling that wherein experimental group 1~7 is prepared using embodiment 1~7 respectively is pasted.
3rd, instructions of taking：Experimental group 1~7 pastes scar patch of dispelling respectively, a piece of daily, continuous patch 50 days.Control group uses silk cottonrose hibiscus Kang Meiguo imported with original packaging scar plasters.
4th, curative effect judging standard
Cure：Patient's scar symptom disappears, and body surface recovers normal；
Effectively：Patient's scar symptom gradually mitigates or symptom disappears；
It is invalid：Scar symptom is without improvement；
Total effective rate=(curing number of cases+effective number of cases)/case load.
5th, result is as shown in table 1
The treatment results of the experimental group 1~7 of table 1 and control group
Scar of being dispelled above to one kind provided by the invention patch and preparation method thereof is described in detail, used herein Specific case is set forth to the principle and embodiment of the present invention, and the explanation of above example is only intended to help and understands this The method and its core concept of invention, it is noted that for those skilled in the art, do not departing from this hair On the premise of bright principle, some improvement and modification can also be carried out to the present invention, these are improved and modification also falls into power of the present invention In the protection domain that profit requires.

Claims (7)

1. one kind is dispelled, scar is pasted, it is characterised in that including tack coat and the medicine layer being arranged on the tack coat, the medicine layer Include the raw material of following parts by weight：
2. scar patch as claimed in claim 1 of dispelling, it is characterised in that the medicine layer includes the raw material of following parts by weight：
3. scar patch as claimed in claim 1 or 2 of dispelling, it is characterised in that be also including auxiliary material, the parts by weight of the auxiliary material 150~200 parts.
4. scar patch as claimed in claim 3 of dispelling, it is characterised in that the auxiliary material includes Sodium Hyaluronate, glycerine, pearl powder And single stearic acid glycerine lipoprotein.
5. a kind of preparation method of scar patch as claimed in claim 1 of dispelling, it is characterised in that comprise the following steps：
Add after carrot meal, mung bean, aloe, rose, lavender, cultivated land, notopterygium root, waxgourd peel, the capsule of weeping forsythia, golden cypress, the root of Dahurain angelica are crushed Enter medicine decocting tank, and add water for the first time, after stirring, soak 3~5h；Into the medicine decocting tank, second of addition water, boils Slow fire endures 3~5h afterwards, filtering, obtains the first filtrate；Into the filter residue being filtrated to get for the third time plus water, boil rear slow fire endure 1~ 2h, filtering, obtains the second filtrate；First filtrate and second filtrate are merged, concentration, added into the material after concentration Enter ursolic acid and vitamin B, be coated onto after well mixed on cohesive carrier, and toast 3~5min at 40~50 DEG C and be Obtain scar patch of dispelling.
6. preparation method as claimed in claim 5, it is characterised in that also include adding auxiliary material into the material after concentration.
7. preparation method as claimed in claim 5, it is characterised in that the first time add the dosage of water be the carrot meal, The mung bean, the aloe, the rose, the lavender, the cultivated land, the notopterygium root, the waxgourd peel, the company Stick up, the golden cypress, 2~3 times of the root of Dahurain angelica；Described second plus water dosage be the carrot meal, it is the mung bean, described Aloe, the rose, the lavender, the cultivated land, the notopterygium root, the waxgourd peel, the capsule of weeping forsythia, the golden cypress, institute State root of Dahurain angelica total amount 4~6 times；The dosage of the third time feedwater is the carrot meal, the mung bean, the aloe, the rose Rare flower, the lavender, the cultivated land, the notopterygium root, the waxgourd peel, the capsule of weeping forsythia, the golden cypress, the root of Dahurain angelica total amount 2~3 times.
CN201710547216.3A 2017-07-06 2017-07-06 Scar of dispelling patch and preparation method thereof Pending CN107375614A (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN115531489A (en) * 2022-08-27 2022-12-30 浙江金圳健康科技有限公司 Scar-removing traditional Chinese medicine composition and preparation method thereof

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104490649A (en) * 2014-11-28 2015-04-08 马鞍山永邦咨询服务有限公司 Pure natural scar-removing plant beautifying powder and preparation method thereof

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104490649A (en) * 2014-11-28 2015-04-08 马鞍山永邦咨询服务有限公司 Pure natural scar-removing plant beautifying powder and preparation method thereof

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN115531489A (en) * 2022-08-27 2022-12-30 浙江金圳健康科技有限公司 Scar-removing traditional Chinese medicine composition and preparation method thereof

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Application publication date: 20171124