CN115508166A - Leucorrhea sample pretreatment device based on test tube with specific structure - Google Patents

Leucorrhea sample pretreatment device based on test tube with specific structure Download PDF

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Publication number
CN115508166A
CN115508166A CN202211302048.9A CN202211302048A CN115508166A CN 115508166 A CN115508166 A CN 115508166A CN 202211302048 A CN202211302048 A CN 202211302048A CN 115508166 A CN115508166 A CN 115508166A
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China
Prior art keywords
test tube
cotton swab
sample
cavity
specific structure
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CN202211302048.9A
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CN115508166B (en
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梁湘辉
梁光明
危加胜
刘济群
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Hunan Youzhe Technology Co ltd
Xiangya Hospital of Central South University
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Hunan Youzhe Technology Co ltd
Xiangya Hospital of Central South University
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    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00Sampling; Preparing specimens for investigation
    • G01N1/28Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B10/00Other methods or instruments for diagnosis, e.g. instruments for taking a cell sample, for biopsy, for vaccination diagnosis; Sex determination; Ovulation-period determination; Throat striking implements
    • A61B10/0045Devices for taking samples of body liquids
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/508Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above
    • B01L3/5082Test tubes per se
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00Sampling; Preparing specimens for investigation
    • G01N1/28Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/38Diluting, dispersing or mixing samples
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B10/00Other methods or instruments for diagnosis, e.g. instruments for taking a cell sample, for biopsy, for vaccination diagnosis; Sex determination; Ovulation-period determination; Throat striking implements
    • A61B10/0045Devices for taking samples of body liquids
    • A61B2010/0074Vaginal or cervical secretions

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  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pathology (AREA)
  • Analytical Chemistry (AREA)
  • Hematology (AREA)
  • Immunology (AREA)
  • General Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • Biomedical Technology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Surgery (AREA)
  • Clinical Laboratory Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Molecular Biology (AREA)
  • Medical Informatics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Engineering & Computer Science (AREA)
  • Sampling And Sample Adjustment (AREA)

Abstract

The invention discloses a leucorrhea specimen pretreatment device based on a test tube with a specific structure, which belongs to the field of medical instruments and comprises: a cuvette, the cuvette comprising: the test tube lid, test tube body and cotton swab, the top at the test tube body is connected to the test tube lid, it is internal that the cotton swab runs through the test tube lid and stretches into the test tube, the test tube is covered and is provided with cotton swab stirring mouth and rifle head sample connection, be provided with the direction interior limit between cotton swab stirring mouth and the rifle head sample connection, the one end that rifle head sample connection was kept away from to cotton swab stirring mouth is provided with spacing limit, the internal cotton swab mixing cavity that is provided with of test tube, direct cavity of sample liquid and sample liquid sample cavity, cotton swab mixing cavity, the direct cavity of sample liquid and sample liquid sample cavity communicate each other. The test tube of the invention separates the mixing position and the sampling position of the sample liquid, so that the mixing process and the sampling process are not interfered with each other. After the traditional equipment is uniformly mixed, the cover needs to be opened, the cotton swab in the cover is taken out, and then the sample is sucked, so that a cover opening mechanism is omitted, and the equipment cost is reduced.

Description

Leucorrhea sample pretreatment device based on test tube with specific structure
Technical Field
The invention belongs to the field of medical instruments, and particularly relates to a leucorrhea specimen pretreatment device based on a test tube with a specific structure.
Background
At present, the pretreatment form of the leucorrhea specimen is generally divided into two types, one is a manual form, and the other is an automatic form. The manual form is that the manual work is put the cotton swab sample to the soft test tube of PP, and the manual work is injected into the diluent, and the hand is held between the fingers the cotton swab and is carried out the sample elution mixing, then will dilute the dissolved liquid sample and pour into the short test tube that the machine can handle in, place and send a kind position at the instrument, remove to detect the position and carry out the sample processing. The automatic mode is to add a pretreatment structure, realize the automation of sample dilute, shake even, then break the cotton swab, abandon the cotton swab pole, keep the cotton swab head in the sample liquid, send to the testing position and carry out the sampling processing.
The problems existing in the existing artificial form are as follows: firstly, the sample solution is easy to cause cross infection due to manual contact. Secondly, the kneading process is performed by hands, the manual experience and occupation operation of workers are all relied on, and the situation of incomplete mixing is easy to occur due to the emotion of the workers and other reasons in the mixing process. Thirdly, in case of liquid transfer, the liquid may be poured out during the pouring process, which results in contamination of the working site.
The problems of the existing automatic form are as follows: most of the existing devices in the market adopt cotton swab sampling devices with the same opening, and the device needs to be punctured or opened when diluent is added; the cotton swab is stirred and then the sample is sucked, and the sample is automatically opened once, so that the pretreatment equipment needs a complex cover opening mechanism, the cost is increased, and the reliability of the instrument is reduced.
Disclosure of Invention
The invention aims to provide a leucorrhea specimen pretreatment device based on a test tube with a specific structure, which solves the defects in the prior art.
In order to achieve the purpose, the invention adopts the technical scheme that:
a leucorrhea specimen pretreatment device based on a test tube with a specific structure comprises: a cuvette, the cuvette comprising: test tube lid, test tube body and cotton swab, the test tube lid is connected the top of test tube body, the cotton swab runs through the test tube lid stretches into the test tube is internal, the test tube is covered and is provided with cotton swab stirring mouth and rifle head sample connection, be provided with the direction in between cotton swab stirring mouth and the rifle head sample connection, cotton swab stirring mouth is kept away from the one end of rifle head sample connection is provided with spacing limit, be provided with the direct cavity of cotton swab mixing cavity, appearance liquid and appearance liquid sample cavity in the test tube, the direct cavity of cotton swab mixing cavity, appearance liquid and appearance liquid sample cavity communicate each other.
Preferably, the upper end of the cotton swab stirring port is a straight-through small opening, the lower end of the cotton swab stirring port is a conical opening, and the gun head sampling port is located at a lower position of the side edge of the cotton swab stirring port.
Preferably, the lower extent of the guide inner edge exceeds the bottom end of the cuvette lid.
Preferably, still include preceding processing mechanism, preceding processing mechanism includes the workstation, be provided with the sample presentation equipment on the workstation, be provided with the test-tube rack on the sample presentation equipment, the test tube is arranged in the test-tube rack, the top of workstation is provided with the sample arm.
Preferably, the sampling arm comprises: the automatic feeding device comprises a rack, wherein a screw rod motor is arranged at the top end of the rack, a sliding block is in threaded connection with the output end of the screw rod motor, a rotating motor is fixedly connected onto the sliding block, a uniformly mixing rotating head is fixedly connected onto the output end of the rotating motor, and a dilution needle is further arranged on the sliding block.
Preferably, the inner wall of the rack is further provided with a guide rail, and the guide rail is in sliding fit with the sliding block.
Preferably, the middle part of workstation is identification station, identification station is provided with sensor and bar code scanner, the sensor is used for detecting whether there is the test tube to pass through, bar code scanner is used for reading the bar code numerical value on the test tube.
Compared with the prior art, the leucorrhea specimen pretreatment device based on the test tube with the specific structure provided by the invention has the following advantages:
(1) The test tube of the invention separates the mixing position and the sampling position of the sample liquid, so that the mixing process and the sampling process are not interfered with each other. After the mixing of traditional equipment has been avoided, need open the lid, take out the operating mode that the cotton swab siphoned the appearance again wherein, saved uncapping mechanism, reduced equipment cost.
(2) According to the invention, the sample is uniformly mixed by rotating the cotton swab by the uniformly mixing rotating head, so that the mode of pinching the test tube by hands in the prior art is changed, two hands are liberated, and the probability of contact infection is reduced.
Drawings
In order to more clearly illustrate the embodiments of the present invention or the technical solutions in the prior art, the drawings used in the embodiments or the prior art descriptions will be briefly described below, it is obvious that the drawings in the following description are only embodiments of the present invention, and for those skilled in the art, other drawings can be obtained according to the provided drawings without creative efforts.
FIG. 1 is a schematic view of the structure of a test tube according to the present invention;
FIG. 2 is a top view of the test tube of the present invention;
FIG. 3 is a front cross-sectional view of a test tube cover according to the present invention;
FIG. 4 is a front sectional view of a test tube body according to the present invention;
fig. 5 is a schematic view of the overall structure of the present invention.
In the figure: the test tube sampling method comprises the following steps of 1-a test tube, 11-a test tube cover, 111-a cotton swab stirring port, 112-a gun head sampling port, 113-a guide inner edge, 114-a limiting edge, 12-a test tube body, 121-a sample liquid direct cavity, 122-a sample liquid sampling cavity, 123-a cotton swab mixing cavity, 13-a cotton swab, 2-a sampling arm, 21-a mixing rotating head, 22-a rotating motor, 23-a screw motor, 24-a dilution needle, 3-sample conveying equipment, 31-a sensor, 32-a code scanner and 4-a test tube rack.
Detailed Description
The technical scheme of the invention is further explained by combining the drawings and the embodiment as follows:
referring to fig. 1 to 5, the present invention provides a leucorrhea specimen pretreatment apparatus based on a test tube with a specific structure, comprising: a cuvette 1, said cuvette 1 comprising: test tube lid 11, test tube body 12 and cotton swab 13, test tube lid 11 is connected the top of the test tube 12 body, cotton swab 13 runs through test tube lid 11 and stretch into in the test tube body 12, test tube lid 11 has set gradually cotton swab stirring mouth 111 and rifle head sample connection 112 from a left side right side, be provided with direction interior limit 113 between cotton swab stirring mouth 111 and the rifle head sample connection 112, cotton swab stirring mouth 111 is kept away from the one end of rifle head sample connection 112 is provided with spacing limit 114, test tube body 12 has set gradually cotton swab mixing cavity 123, sample liquid through cavity 121 and sample liquid sample cavity 122 from a left side right side, cotton swab mixing cavity 123, sample liquid through cavity 121 and sample liquid sample cavity 122 communicate each other. The limiting edge 114 is clamped with the flange of the test tube rack 4, so that the situation that the test tube cover 11 is taken out of the test tube rack to cause uncontrollable position when the sliding block moves upwards is prevented.
As a preferred embodiment, the upper end of the cotton swab stirring port 111 is a straight small opening, the lower end of the cotton swab stirring port is a tapered opening, and the lance tip sampling port 112 is located at a lower position on the side of the cotton swab stirring port 111. The distance from the sampling port 112 of the gun head to the bottom surface of the test tube 1 is short, so that the time required for the up-and-down movement of the device during sampling can be reduced.
In a preferred embodiment, the lower extent of the guiding inner edge 113 extends beyond the bottom end of the cuvette lid 11. The inner guide edge 113 is used for limiting the downward movement direction of the gun head and improving the stability of the gun head in the downward movement sampling process.
As a preferred embodiment, still include preceding processing mechanism, preceding processing mechanism includes the workstation, be provided with sample presentation equipment 3 on the workstation, be provided with test-tube rack 4 on the sample presentation equipment 3, test tube 1 is arranged in the test-tube rack 4, the top of workstation is provided with sampling arm 2. The sampling arm 2 comprises: the automatic feeding device comprises a frame, the top of frame is provided with lead screw motor 23, the output end threaded connection of lead screw motor 23 has the slider, fixedly connected with rotating electrical machines 22 on the slider, rotating electrical machines 22's output fixedly connected with mixing rotating head 21, still be provided with dilution needle 24 on the slider. The inner wall of the rack is also provided with a guide rail, and the guide rail is in sliding fit with the sliding block. The middle part of workstation is identification position, identification position is provided with sensor 31 and bar code scanner 32, sensor 31 is used for detecting whether there is test tube 1 to pass through, bar code scanner 32 is used for reading the bar code numerical value on the test tube 1.
The working principle of the invention is as follows:
through the propelling movement of sample conveying equipment 3, make test tube 1 move to the discernment station along with test-tube rack 4, sensor 31 judges whether to have test tube 1 on the station after through optical detection. When the test tube 1 is determined, the sampling arm 2 starts to move to the upper part of the test tube 1 for the next operation.
The screw motor 23 starts to drive the slider to move downwards, and the cotton swab rod with the set length is broken in the cotton swab stirring port 111 of the test tube 1 due to the fact that the blending rotating head 21 faces the cotton swab stirring port 111 of the test tube 1. When the blending rotating head 21 is opposite to the cotton swab head, a dilution needle 24 is obliquely arranged on the sliding block, the dilution needle 24 is right opposite to the sampling port 112 of the gun head of the test tube 1 at the moment, the upper end of the dilution needle 24 is connected with a peristaltic pump through a pipe, and the other end of the peristaltic pump is connected with a dilution liquid bottle. And the mixing rotating head 21 hole has screens mechanism and prevents the rotation bottom surface, and the hole and the cotton swab stick pole of this moment mixing rotating head 21 are connected, then start rotating electrical machines 22, and cotton swab 13 then can follow the quick rotation of mixing rotating head 21.
The cotton head of cotton swab 13 lower part is rotatory in being taken the diluent, and the diluent of test tube 1 bottom then can be stirred in the fast revolution of cotton swab 13, and test tube 1 bottom is divided into two chambeies, and the shape is peculiar, so the diluent that cotton swab 13 stirred can not do circular motion, at this moment will lead to the interior liquid turbulence of test tube 1 to incessantly wash the surface of cotton swab 13. Simultaneously cotton swab 13 is rotatory, incessantly with the contact of dilution liquid, and the sample drops from cotton swab 13 among the contact process to in the dilution of mixing in test tube 1, form and detect required appearance liquid.
After the set time of the blending, the screw motor 23 of the sampling arm 2 drives the slider to move upwards, and the swab 13 is separated from the blending rotating head 21. And (5) uniformly mixing.
In the description of the present application, it should be noted that the terms "upper", "lower", and the like indicate orientations or positional relationships based on the orientations or positional relationships shown in the drawings, which are only for convenience in describing the present application and simplifying the description, and do not indicate or imply that the referred device or element must have a specific orientation, be constructed in a specific orientation, and operate, and thus, should not be construed as limiting the present application. Unless expressly stated or limited otherwise, the terms "mounted," "connected," and "coupled" are to be construed broadly and encompass, for example, both fixed and removable coupling as well as integral coupling; can be mechanically or electrically connected; they may be connected directly or indirectly through intervening media, or they may be interconnected between two elements. The specific meaning of the above terms in the present application can be understood by those of ordinary skill in the art as appropriate.
It is noted that, in the present application, relational terms such as "first" and "second", and the like, are used solely to distinguish one entity or action from another entity or action without necessarily requiring or implying any actual such relationship or order between such entities or actions. Also, the terms "comprises," "comprising," or any other variation thereof, are intended to cover a non-exclusive inclusion, such that a process, method, article, or apparatus that comprises a list of elements does not include only those elements but may include other elements not expressly listed or inherent to such process, method, article, or apparatus. Without further limitation, an element defined by the phrases "comprising a," "8230," "8230," or "comprising" does not exclude the presence of additional like elements in a process, method, article, or apparatus that comprises the element.
The previous description is only an example of the present application, and is provided to enable any person skilled in the art to understand or implement the present application. Various modifications to these embodiments will be readily apparent to those skilled in the art, and the generic principles defined herein may be applied to other embodiments without departing from the spirit or scope of the application. Thus, the present application is not intended to be limited to the embodiments shown herein but is to be accorded the widest scope consistent with the principles and novel features disclosed herein.

Claims (7)

1. A leucorrhea specimen pretreatment device based on a test tube with a specific structure comprises: test tube (1), characterized in that the test tube (1) comprises: test tube lid (11), test tube body (12) and cotton swab (13), test tube lid (11) are connected the top of test tube (12) body, cotton swab (13) run through test tube lid (11) and stretch into in test tube body (12), be provided with cotton swab stirring mouth (111) and rifle head sample connection (112) on test tube lid (11), be provided with direction interior limit (113) between cotton swab stirring mouth (111) and rifle head sample connection (112), cotton swab stirring mouth (111) are kept away from the one end of rifle head sample connection (112) is provided with spacing limit (114), be provided with cotton swab mixing cavity (123), the direct cavity of sample liquid (121) and sample liquid sampling cavity (122) in test tube body (12), cotton swab mixing cavity (123), the direct cavity of sample liquid (121) and sample liquid sampling cavity (122) communicate each other.
2. The leucorrhea specimen pretreatment device based on the test tube with specific structure as claimed in claim 1, wherein said cotton swab stirring port (111) has a through small opening at its upper end and a tapered opening at its lower end, and said lance tip sampling port (112) is located at a lower position on the side of said cotton swab stirring port (111).
3. The leucorrhea specimen pretreatment device with specific structure based on test tube according to claim 1, wherein said inner guide edge (113) extends beyond the bottom end of said test tube cover (11).
4. The leucorrhea specimen pretreatment device based on the test tube with specific structure according to claim 1, further comprising a pretreatment mechanism, wherein said pretreatment mechanism comprises a workbench, a sample feeding device (3) is disposed on said workbench, a test tube rack (4) is disposed on said sample feeding device (3), said test tube (1) is disposed in said test tube rack (4), and a sampling arm (2) is disposed above said workbench.
5. The leucorrhea specimen pretreatment apparatus based on test tube with specific structure as claimed in claim 4, wherein said sampling arm (2) comprises: the automatic feeding device comprises a frame, the top of frame is provided with lead screw motor (23), the output threaded connection of lead screw motor (23) has the slider, fixedly connected with rotating electrical machines (22) on the slider, the output fixedly connected with mixing rotating head (21) of rotating electrical machines (22), still be provided with on the slider and dilute needle (24).
6. The leucorrhea specimen pretreatment device based on specific structure test tube of claim 5, wherein said inner wall of said frame is further provided with a guide rail, said guide rail is slidably engaged with said slide block.
7. The leucorrhea sample pretreatment apparatus based on test tubes with specific structures as claimed in claim 4, wherein said work table is provided with a recognition station at the middle, said recognition station is provided with a sensor (31) and a barcode reader (32), said sensor (31) is used for detecting whether there is a test tube (1) passing through, said barcode reader (32) is used for reading the barcode value on the test tube (1).
CN202211302048.9A 2022-10-24 2022-10-24 Leucorrhea sample preprocessing device based on special structure test tube Active CN115508166B (en)

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Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105997156A (en) * 2016-06-12 2016-10-12 杭州昕龙医疗科技有限公司 Sampling swab for full-automatic pretreatment
WO2017081413A1 (en) * 2015-11-13 2017-05-18 Horiba Abx Sas Device for agitating and collecting biological liquid samples suitable for sorting
CN111207946A (en) * 2020-03-12 2020-05-29 珠海科域生物工程股份有限公司 Disposable specimen collecting cup and puncturing and uniformly mixing method thereof
CN111830267A (en) * 2020-08-14 2020-10-27 深圳市瀚德标检生物工程有限公司 Pretreatment system for vaginal secretion sample detection
CN112180106A (en) * 2020-10-15 2021-01-05 珠海科域生物工程股份有限公司 Puncture liquid feeding mixing machine
WO2022068523A1 (en) * 2020-09-29 2022-04-07 江苏百英吉生命科学技术有限公司 Detection system for detecting biological fluid sample
CN114646523A (en) * 2020-12-17 2022-06-21 深圳市帝迈生物技术有限公司 Blending device and sample analyzer

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2017081413A1 (en) * 2015-11-13 2017-05-18 Horiba Abx Sas Device for agitating and collecting biological liquid samples suitable for sorting
CN105997156A (en) * 2016-06-12 2016-10-12 杭州昕龙医疗科技有限公司 Sampling swab for full-automatic pretreatment
CN111207946A (en) * 2020-03-12 2020-05-29 珠海科域生物工程股份有限公司 Disposable specimen collecting cup and puncturing and uniformly mixing method thereof
CN111830267A (en) * 2020-08-14 2020-10-27 深圳市瀚德标检生物工程有限公司 Pretreatment system for vaginal secretion sample detection
WO2022068523A1 (en) * 2020-09-29 2022-04-07 江苏百英吉生命科学技术有限公司 Detection system for detecting biological fluid sample
CN112180106A (en) * 2020-10-15 2021-01-05 珠海科域生物工程股份有限公司 Puncture liquid feeding mixing machine
CN114646523A (en) * 2020-12-17 2022-06-21 深圳市帝迈生物技术有限公司 Blending device and sample analyzer

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