CN217466952U - Full-automatic thrombelastogram instrument - Google Patents

Full-automatic thrombelastogram instrument Download PDF

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Publication number
CN217466952U
CN217466952U CN202220623696.3U CN202220623696U CN217466952U CN 217466952 U CN217466952 U CN 217466952U CN 202220623696 U CN202220623696 U CN 202220623696U CN 217466952 U CN217466952 U CN 217466952U
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driving
blood sample
cup
driving device
cabin
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艾峰
黄阁锋
黄振宁
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Shenzhen Youdi Biotechnology Co ltd
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Shenzhen Youdi Biotechnology Co ltd
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    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/02Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations
    • G01N35/04Details of the conveyor system
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing

Abstract

The utility model discloses a full-automatic thrombelastogram instrument, which comprises a hood, a three-coordinate driving device, a sampling device, a testing device, a blood sample storage cabin, a reagent storage cabin and a reaction cup storage cabin, wherein the three-coordinate driving device, the sampling device, the testing device, the blood sample storage cabin, the reagent storage cabin and the reaction cup storage cabin are arranged in the hood; the three-coordinate driving device is connected with the sampling device and is used for driving the sampling device to horizontally move and lift above the reaction cup storage cabin, the blood sample storage cabin and the reagent storage cabin; the sampling device is used for grabbing a target reaction cup in the reaction cup containing cabin to the testing device under the driving of the three-coordinate driving device, and the sampling device is used for extracting a target blood sample in the blood sample containing cabin and a target reagent in the reagent containing cabin and injecting the target blood sample and the target reagent into the target reaction cup under the driving of the three-coordinate driving device; the testing device is used for carrying out blood sample detection operation on the target reaction cup. The utility model discloses a full-automatic thrombelastogram appearance can solve current thrombelastogram appearance efficiency of software testing low down and cause the extravagant technical problem of human cost because of needing artifical supplementary.

Description

Full-automatic thrombelastogram instrument
The present application claims priority from the chinese patent application entitled "full-automatic thromboelastogram apparatus and blood sample testing method" filed by the chinese patent office at 18/11/2021 under the application number 202111365455.X, which is incorporated herein by reference in its entirety.
Technical Field
The utility model belongs to the technical field of medical equipment, concretely relates to full-automatic thrombelastogram appearance.
Background
The thromboelastogram instrument is an analysis instrument for monitoring a blood coagulation process based on the whole dynamic process of platelet aggregation, blood coagulation, fibrinolysis and the like, and obtains blood coagulation parameter information of a blood sample by monitoring, testing and analyzing the blood coagulation process of the blood sample, and accordingly, blood coagulation assessment which has important reference significance for predicting clinical conditions is made.
Blood sample detection needs to be performed by means of multiple reagents, so the workflow of performing blood sample test by using the thromboelastography involves various pretreatment operations on the blood sample and the reagents. At present, due to the technical limit, the operation is generally finished in a manual mode, the efficiency is low, and the labor cost is high.
SUMMERY OF THE UTILITY MODEL
In order to overcome the above shortcoming of prior art, the utility model aims at providing a full-automatic thrombelastogram appearance aims at solving current thrombelastogram appearance and needs artifical supplementary in the preliminary treatment operation of carrying out blood specimen test in-process, leads to efficiency of software testing low and causes the extravagant technical problem of human cost from this.
The utility model discloses a reach its purpose, the technical scheme who adopts as follows:
a full-automatic thrombelastogram instrument comprises a hood, a three-coordinate driving device, a sampling device, a testing device, a blood sample receiving cabin, a reagent receiving cabin and a reaction cup receiving cabin; wherein:
the three-coordinate driving device, the sampling device, the testing device, the blood sample receiving cabin, the reagent receiving cabin and the reaction cup receiving cabin are all arranged inside the hood, and the three-coordinate driving device is connected with the sampling device;
the three-coordinate driving device is used for driving the sampling device to horizontally move and lift above the reaction cup containing cabin, the blood sample containing cabin and the reagent containing cabin; the sampling device is used for grabbing a target reaction cup in the reaction cup containing cabin onto the testing device under the driving of the three-coordinate driving device, and the sampling device is used for extracting a target blood sample in the blood sample containing cabin and a target reagent in the reagent containing cabin and injecting the target blood sample into the target reaction cup under the driving of the three-coordinate driving device;
the testing device is used for carrying out blood sample detection operation on the target reaction cup.
Further, the three-coordinate driving device comprises a first driving device and a second driving device, the sampling device comprises a first mechanical arm, a second mechanical arm and a sampler, and the full-automatic thrombelastogram instrument further comprises a blending device and an activation cabin; wherein:
the blending device and the activation cabin are both arranged inside the hood;
the first driving device is connected with the first mechanical arm; the first driving device is used for driving the first mechanical arm to grab the target blood sample to the blending device; the blending device is used for blending the target blood sample to obtain a blended blood sample; the target reagent comprises a first reagent and a second reagent, and the first driving device is used for driving the first mechanical arm to grab the first reagent into the activation cabin;
the second driving device is connected with the second mechanical arm and the sampler; the second driving device is used for driving the second mechanical arm to grab the target reaction cup onto the testing device; the second driving device is used for driving the sampler to extract the mixed blood sample into the activation cabin, so that the mixed blood sample and the first reagent are activated to obtain an activated blood sample; the second driving device is used for driving the sampler to extract the activated blood sample into the target reaction cup on the testing device; the second driving device is used for driving the sampler to extract the second reagent into the target reaction cup on the testing device.
Further, the sampler comprises a first sampling needle and a second sampling needle; wherein:
the second driving device is used for driving the first sampling needle to extract the mixed blood sample into the activation cabin, so that the mixed blood sample and the first reagent are activated; the second driving device is used for driving the first sampling needle to extract the activated blood sample into the target reaction cup on the testing device; the second driving device is used for driving the second sampling needle to extract the second reagent into the target reaction cup on the testing device.
Further, the full-automatic thrombelastogram instrument further comprises a cleaning device; wherein:
the cleaning device is arranged inside the hood and used for cleaning the first sampling needle and the second sampling needle.
Further, the full-automatic thrombelastogram instrument further comprises a recovery cabin; the recovery cabin is arranged in the hood and communicated with the outside of the hood; the first driving device is used for driving the first mechanical arm to grab the extracted activated blood sample and pour the blood sample into the recovery cabin; the second driving device is used for driving the second mechanical arm to grab the detected target reaction cup and pour the target reaction cup into the recovery cabin.
Further, the full-automatic thromboelastography instrument further comprises a disinfection device; the sterilizing device is arranged at the blending device and is used for sterilizing the blended blood sample.
Further, full-automatic thrombelastogram appearance still includes the display and controls the panel, the display is controlled the panel and is set up in on the lateral wall of aircraft bonnet.
Further, the lateral wall of aircraft bonnet is seted up just to the entry is put to the blood sample of blood sample containing compartment, full-automatic thrombelastogram appearance still includes the bar code scanner, the bar code scanner set up in the entry is put to the blood sample.
Further, full-automatic thrombelastogram appearance still includes data interface, data interface set up in on the lateral wall of aircraft bonnet and with testing arrangement electricity is connected, just data interface is used for external terminal equipment.
Furthermore, the testing device comprises a cup seat, an upper cup cover assembly, a lower cup cover assembly and a driving assembly; wherein:
the cup seat is used for fixing the target reaction cup, the upper cup cover assembly and the lower cup cover assembly are connected to the driving assembly, the driving assembly is used for driving the upper cup cover assembly and the lower cup cover assembly to move downwards along the direction of horizontally approaching the cup seat, and the driving assembly is used for driving the upper cup cover assembly and the lower cup cover assembly to move upwards along the direction of horizontally departing from the cup seat;
the upper cup cover assembly and the lower cup cover assembly are used for carrying out cover opening operation and cover closing operation on the target reaction cup on the cup seat.
Further, the driving assembly comprises a first connecting piece, a second connecting piece, a fixed block and a third driving device; wherein:
the third driving device is used for driving the first connecting piece to do vertical lifting motion, the second connecting piece is connected to the first connecting piece in a sliding mode along the horizontal direction, the upper cup cover assembly and the lower cup cover assembly are mounted on the second connecting piece, a sliding piece is arranged on the second connecting piece, the fixing block is provided with a first guide groove which is arranged in an inclined mode, and the sliding piece is matched in the first guide groove in a sliding mode;
when the third driving device drives the first connecting piece to descend, the sliding piece slides along the first guide groove in the downward inclined direction, and the second connecting piece horizontally slides relative to the first connecting piece while descending along with the first connecting piece, so that the upper cup cover assembly and the lower cup cover assembly are close to the cup base;
when the third driving device drives the first connecting piece to ascend, the sliding piece slides along the direction that the first guide groove inclines upwards, and the second connecting piece horizontally slides relative to the first connecting piece while ascending along with the first connecting piece, so that the upper cup cover assembly and the lower cup cover assembly are far away from the cup base;
the upper cup cover assembly and the lower cup cover assembly are used for carrying out cover opening operation and cover closing operation on the target reaction cup on the cup seat.
Furthermore, the upper cup cover assembly and the lower cup cover assembly comprise a fixed seat, a grabbing probe assembly and a fourth driving device; wherein:
the fixed seat is arranged on the second connecting piece, the grabbing probe assembly is connected to the fixed seat in a sliding mode, the fourth driving device is connected with the upper end of the grabbing probe assembly, and the fourth driving device is used for driving the grabbing probe assembly to move up and down relative to the lower end face of the fixed seat;
the lower end face of the fixing seat is used for abutting against the cup cover of the target reaction cup, and the lower end of the grabbing probe assembly is used for being in interference fit with the connecting hole in the cup cover.
Further, the grasping probe assembly includes a grasping probe body and a cylindrical guide; wherein:
the cylinder guide piece is in sliding fit with the fixed seat, the fourth driving device is connected with the upper end of the cylinder guide piece, and the fourth driving device is used for driving the cylinder guide piece to rotate relative to the fixed seat;
the fixed seat is provided with a limiting through groove extending in the vertical direction, the lower end face of the cylindrical guide piece is provided with an accommodating cavity, a spiral second guide groove is formed in the cylindrical surface of the lower end of the cylindrical guide piece and communicated with the accommodating cavity, a protruding sliding part is arranged at the upper end of the grabbing probe body, the grabbing probe body is in sliding fit in the accommodating cavity, and the protruding sliding part penetrates through the second guide groove and the limiting through groove;
when the fourth driving device drives the cylindrical guide piece to rotate, the protruding sliding part slides along the second guide groove and the limiting through groove, so that the grabbing probe body moves up and down relative to the lower end face of the fixing seat, and the lower end of the grabbing probe body is in interference fit with the connecting hole.
Compared with the prior art, the beneficial effects of the utility model are that:
the utility model provides a full-automatic thrombelastogram appearance accomodates the cabin top through three-coordinate drive arrangement drive sampling device at blood specimen storage compartment, reagent storage compartment and reaction cup and removes to accomplish automatically and snatch the target reaction cup to testing arrangement on, draw target blood specimen and target reagent and pour into the operation in the target reaction cup on the testing arrangement, finally detect the sample that awaits measuring in the target reaction cup through testing arrangement, in order to obtain the analysis result that detects. The operation is carried out in an automatic mode, manual intervention is not needed, the blood sample testing efficiency is improved, and the labor cost is saved.
Drawings
In order to more clearly illustrate the embodiments of the present invention or the technical solutions in the prior art, the drawings needed to be used in the description of the embodiments or the prior art will be briefly described below, it is obvious that the drawings in the following description are only some embodiments of the present invention, and for those skilled in the art, other drawings can be obtained according to the structures shown in the drawings without creative efforts.
FIG. 1 is a top view of the internal structure of a first embodiment of the fully automatic thromboelastogram apparatus of the present invention;
FIG. 2 is a schematic view of the internal structure of the first embodiment of the fully automatic thromboelastogram apparatus of the present invention;
FIG. 3 is an external schematic view of a first embodiment of the fully automatic thromboelastogram apparatus of the present invention;
FIG. 4 is a schematic structural diagram of a first driving device in a second embodiment of the fully automatic thromboelastogram apparatus of the present invention;
FIG. 5 is a schematic structural diagram of a second driving device in a second embodiment of the fully automatic thromboelastogram apparatus of the present invention;
FIG. 6 is an exploded view of a third embodiment of the full-automatic thrombelastogram apparatus of the present invention;
fig. 7 is a schematic view of a first visual angle structure of a testing device in a third embodiment of the full-automatic thromboelastogram apparatus of the present invention;
fig. 8 is a second view structural diagram of the testing device in the third embodiment of the fully automatic thromboelastogram apparatus of the present invention;
FIG. 9 is an exploded view of a cup holder and a target reaction cup in a third embodiment of the full-automatic thromboelastogram apparatus of the present invention;
FIG. 10 is an exploded view of the upper and lower cup cover assemblies in a fourth embodiment of the full-automatic thromboelastography device of the present invention;
fig. 11 is an assembly structure diagram of the upper and lower cup cover assemblies in the fourth embodiment of the full-automatic thrombelastogram apparatus of the present invention.
Description of reference numerals:
reference numerals Name (R) Reference numerals Name (R)
1 Hood 205 Cup holder
2 Testing device 206 Third driving device
3 Blood sample storage cabin 801 First mechanical arm
4 Reagent storage compartment 802 Second mechanical arm
5 Reaction cup storage cabin 803 First sampling needle
6 First driving device 804 Second sampling needle
7 Second driving device 1201 Waste throwing channel
8 Sampling device 2011 Fixed seat
9 Blending device 2012 Grabbing probe body
10 Activation cabin 2013 Cylindrical guide
11 Cleaning device 2014 Fourth driving device
12 Recovery cabin 2031 Sliding member
13 Code scanner 2041 First guide groove
14 Data interface 2051 Cup body
15 Display control panel 2052 Cup cover
101 Blood sample inlet 20111 Limiting through groove
201 Upper and lower cup cover assembly 20121 Connecting bolt
202 First connecting piece 20131 Containing cavity
203 Second connecting piece 20132 Second guide groove
204 Fixed block 20521 Connecting hole
The objects, features and advantages of the present invention will be further described with reference to the accompanying drawings.
Detailed Description
The technical solutions in the embodiments of the present invention will be described clearly and completely with reference to the accompanying drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only some embodiments of the present invention, not all embodiments. Based on the embodiments in the present invention, all other embodiments obtained by a person skilled in the art without creative efforts belong to the protection scope of the present invention.
It should be noted that if directional indications (such as up, down, left, right, front, and back … …) are involved in the embodiment of the present invention, the directional indications are only used to explain the relative position relationship between the components, the motion situation, etc. in a specific posture, and if the specific posture is changed, the directional indications are changed accordingly.
In addition, if there is a description relating to "first", "second", etc. in the embodiments of the present invention, the description of "first", "second", etc. is for descriptive purposes only and is not to be construed as indicating or implying relative importance or implicitly indicating the number of technical features indicated. Thus, a feature defined as "first" or "second" may explicitly or implicitly include at least one such feature. In addition, if the meaning of "and/or" and/or "appears throughout, the meaning includes three parallel schemes, for example," A and/or B "includes scheme A, or scheme B, or a scheme satisfying both schemes A and B. In addition, the technical solutions in the embodiments may be combined with each other, but it must be based on the realization of those skilled in the art, and when the technical solutions are contradictory or cannot be realized, the combination of the technical solutions should not be considered to exist, and is not within the protection scope of the present invention.
Referring to fig. 1 to 3, an embodiment of the present invention provides a full-automatic thromboelastogram apparatus, which includes a hood 1, a three-coordinate driving device (not shown), a sampling device 8, a testing device 2, a blood sample storage compartment 3, a reagent storage compartment 4, and a reaction cup storage compartment 5; wherein:
the three-coordinate driving device, the sampling device 8, the testing device 2, the blood sample containing cabin 3, the reagent containing cabin 4 and the reaction cup containing cabin 5 are all arranged inside the hood 1, and the three-coordinate driving device is connected with the sampling device 8;
the three-coordinate driving device is used for driving the sampling device 8 to horizontally move and lift above the reaction cup containing cabin 5, the blood sample containing cabin 3 and the reagent containing cabin 4; the sampling device 8 is used for grabbing a target reaction cup in the reaction cup containing cabin 5 onto the testing device 2 under the driving of the three-coordinate driving device, and the sampling device 8 is used for extracting a target blood sample in the blood sample containing cabin 3 and a target reagent in the reagent containing cabin 4 and injecting the target blood sample into the target reaction cup under the driving of the three-coordinate driving device;
the testing device 2 is used to perform a blood sample testing operation on a target cuvette.
In the present embodiment, illustratively, a working platform is provided inside the hood 1, and the blood sample receiving compartment 3, the reagent receiving compartment 4 and the cuvette receiving compartment 5 are provided in different horizontal areas on the working platform. Blood sample and reagent hold respectively in blood sample bottle and reagent pipe, are provided with a plurality of positions that hold that are used for holding blood sample bottle, reagent pipe and reaction cup in blood sample storage chamber 3, reagent storage chamber 4 and the reaction cup storage chamber 5 respectively. The reaction cups are filled with reactants (such as heparinase, platelets and the like), the reaction cups filled with different reactants can be respectively contained in the containing positions of different areas in the reaction cup containing cabin 5, and different reaction cups can be selected according to requirements during blood sample testing. The side wall of the hood 1 can be provided with a hinged cabin door so that a worker can conveniently open the cabin door to place or replace the blood sample bottle, the reagent tube and the reaction cup inside and overhaul devices inside the hood 1; the blood sample receiving cabin 3, the reagent receiving cabin 4 or the reaction cup receiving cabin 5 can be arranged into drawer type according to requirements, so that a worker can take out the corresponding receiving cabin from the inside of the hood 1 in a push-pull mode, and the blood sample bottle, the reagent tube and the reaction cup can be placed or replaced rapidly under the condition that devices in the hood 1 are prevented from being touched by mistake.
The three-coordinate driving device is positioned above the blood sample containing cabin 3, the reagent containing cabin 4 and the reaction cup containing cabin 5, and specifically comprises a linear moving device consisting of a motor on each coordinate axis, a ball screw, a guide rail, a track and other devices, so that the sampling device 8 connected to the three-coordinate driving device can move in three coordinate directions, the sampling device 8 can move to the upper part of any containing cabin along a horizontal plane under the driving of the three-coordinate driving device, and the sampling action is completed by the contact of vertical lifting and blood sample bottles, reagent tubes and reaction cups. The sampling device 8 may specifically include a holding assembly (e.g., a mechanical gripper, a finger cylinder, etc.) for gripping the container and a suction assembly (e.g., a sampling needle, a dropper, etc. used with a suction pump) for automatically drawing a blood sample or a reagent from the container.
The testing device 2 may specifically include a base disposed on the plane of the worktable and used for placing the target reaction cup, a testing probe disposed below the base and connected to a terminal device (e.g., a computer), and a cover removing device disposed above the base. In the actual working process, after the target reaction cup in the reaction cup storage compartment 5 is grabbed onto the base by the sampling device 8, the target reaction cup is fixed onto the base in an interference fit manner, the cover fetching part (which may be a suction cup, an electromagnet, a clamping jaw, etc.) of the cover fetching device is driven by the motor to move to the target reaction cup and contact with the cup cover of the reaction cup, and the cup cover fetching part can fetch the cup cover of the reaction cup from the cup body of the reaction cup in an adsorption, clamping, hooking and other manners under the condition of matching with the air pump or other driving parts, and then the sampling device 8 respectively fetches the target blood sample in the blood sample storage compartment 3, the target reagents (which may be various) in the reagent storage compartment 4 and injects them into the cup body of the reaction cup, it should be noted that the target blood sample and the target reagents can be injected into the target reaction cup together for mixing, or can be injected into the target reaction cup after being mixed externally, in practical application, the test device can be flexibly set according to test requirements, and is not limited here. After the injection is finished, the cover taking device covers the cover of the reaction cup on the cup body of the reaction cup again in the same action mode, at the moment, a sample to be tested in the target reaction cup is configured, the test probe below the base body can be contacted with the sample to be tested in the target reaction cup in a puncturing mode and completes sampling test, finally test data are sent to the terminal equipment, and the terminal equipment obtains an analysis result about the target blood sample according to the test data. After the above operations are completed, the next round of test process can be entered.
It can be understood that the above action processes are all controlled by a control module, and the control module may specifically include a control chip or a single chip microcomputer, which can control a plurality of devices according to a predetermined program, so that the three-coordinate driving device and the testing device 2 may start, stop or perform other actions according to a preset flow, wherein the control chip may specifically adopt an STM32F407 chip.
Therefore, the full-automatic thromboelastogram instrument provided by the embodiment drives the sampling device 8 to move above the blood sample storage compartment 3, the reagent storage compartment 4 and the reaction cup storage compartment 5 through the three-coordinate driving device, automatically completes the operations of grabbing the target reaction cup onto the testing device 2, extracting the target blood sample and the target reagent and injecting the target blood sample and the target reagent into the target reaction cup on the testing device 2, and finally detects the sample to be detected in the target reaction cup through the testing device 2 to obtain the detection and analysis result. The operation is carried out in an automatic mode, manual intervention is not needed, the blood sample testing efficiency is improved, and the labor cost is saved.
Further, referring to fig. 1 to 5, in an alternative embodiment, the three-coordinate driving device includes a first driving device 6 and a second driving device 7, the sampling device 8 includes a first mechanical arm 801, a second mechanical arm 802 and a sampler, and the fully automatic thromboelastography apparatus further includes a blending device 9 and an activation cabin 10; wherein:
the blending device 9 and the activation cabin 10 are both arranged in the hood 1;
the first driving device 6 is connected with the first mechanical arm 801; the first driving device 6 is used for driving the first mechanical arm 801 to grab a target blood sample into the blending device 9; the blending device 9 is used for blending the target blood sample to obtain a blended blood sample; the target reagent comprises a first reagent and a second reagent, and the first driving device 6 is used for driving the first mechanical arm 801 to grab the first reagent into the activation chamber 10;
the second driving device 7 is connected with the second mechanical arm 802 and the sampler; the second driving device 7 is used for driving the second mechanical arm 802 to grab the target reaction cup onto the testing device 2; the second driving device 7 is used for driving the sampler to extract the mixed blood sample into the activation cabin 10, so that the mixed blood sample is activated with the first reagent to obtain an activated blood sample; the second driving device 7 is used for driving the sampler to extract the activated blood sample into the target reaction cup on the testing device 2; the second drive means 7 is used to drive the sampler to extract a second reagent into a target reaction cup on the testing device 2.
When there are two kinds of target reagents, and there are a requirement for a mixing order between the target blood sample and each target reagent and a requirement for a reaction time after mixing, it is inefficient to perform a sampling operation by only a single sampling device 8. Therefore, in this embodiment, by providing the first driving device 6 and the second driving device 7, and controlling the two driving devices to respectively drive the first mechanical arm 801, the second mechanical arm 802 and the sampler to perform different operations through the control module, the operations can be performed in a synchronized manner, the time required by each test procedure is reduced, and the efficiency is improved. The operation principle of the first driving device 6 and the second driving device 7 can be referred to the three-coordinate driving device in the previous embodiment, and details are not described here; the first mechanical arm 801 and the second mechanical arm 802 can achieve a grasping function by electrically driving the plurality of clamping portions to retract toward the center, and the sampler can achieve a liquid sucking function by a suction component (such as a sampling needle and a dropper used with a suction pump).
The blending device 9 can be a centrifuge, and a plurality of fixing positions can be arranged on the centrifuge along the circumferential direction so as to simultaneously carry out centrifugal blending operation on a plurality of blood sample bottles containing target blood samples under the control of the control module; activation cabin 10 sets up on the inside work platform of aircraft bonnet 1, including a plurality of places the position for accomodate and hold the reagent pipe that has first reagent and mix after the blending blood sample, make its reaction of standing after can activate, in order to obtain the activation blood sample. After the target blood sample is uniformly mixed and activated, the test accuracy can be further improved.
Based on the above arrangement, the testing device 2 can also be correspondingly arranged in a plurality of numbers, the sampling device 8 can absorb the reagent amount needed by a plurality of or all target reaction cups on the testing device 2 at one time, and can perform sample injection operation into the target reaction cups at one time, so that the waiting time in the process of performing blending operation and activating operation is fully utilized, more target blood samples can be detected in the same time, and the testing efficiency is further improved.
Specifically, referring to fig. 1 to 5, the sampler includes a first sampling pin 803 and a second sampling pin 804; wherein:
the second driving device 7 is used for driving the first sampling needle 803 to extract the mixed blood sample into the activation cabin 10, so that the mixed blood sample and the first reagent are activated; the second driving device 7 is used for driving the first sampling needle 803 to extract an activated blood sample into a target reaction cup on the testing device 2; the second driving device 7 is used for driving the second sampling needle 804 to extract the second reagent into the target reaction cup on the testing device 2.
Specifically, referring to fig. 1 to 5, the fully automatic thromboelastography device further comprises a cleaning device 11; wherein:
the cleaning device 11 is provided inside the hood 1, and the cleaning device 11 is used for cleaning the first sampling needle 803 and the second sampling needle 804.
In the present embodiment, different sampling targets are used to extract different reagents, blood samples or their mixtures, so as to avoid the influence on the accuracy of the detection result due to the adulteration of different types of liquids. The cleaning device 11 is used to clean the sampling needle, so that the influence on the accuracy of the detection result due to the doping of target blood samples or target reagents in different testing processes can be avoided, and the sampling needle can be prevented from being polluted. Specifically, the cleaning device 11 is disposed on the working platform inside the hood 1 and electrically connected to the control module, the cleaning device 11 may include a cleaning solution supply portion and a washing pool, and after the sampling needle extracts the target blood sample or the target reagent, the sampling needle may be driven by the second driving device 7 to move to the cleaning solution supply portion to obtain the cleaning solution, and then move to the washing pool to perform washing. After the cleaning is finished, the sampling needle can continue to perform subsequent sampling operation.
Specifically, referring to fig. 1-5, the fully automatic thromboelastography device further comprises a retrieval compartment 12; the recovery cabin 12 is arranged inside the hood 1 and communicated with the outside of the hood 1; the first driving device 6 is used for driving the first mechanical arm 801 to grab the extracted activated blood sample and pour the blood sample into the recovery cabin 12; the second driving device 7 is used for driving the second mechanical arm 802 to grab the detected target reaction cup and pour the target reaction cup into the recovery cabin 12.
In this embodiment, the recovery compartment 12 may include a waste disposal port disposed on the working platform inside the hood 1, and a waste disposal channel 1201 having one end communicating with the waste disposal port and the other end communicating with the outside, a waste hopper for collecting waste materials may be disposed in the waste disposal channel 1201, a reagent tube containing an extracted activated blood sample and a target reaction cup having been detected are discarded in the waste hopper through the waste disposal port, and when the waste materials accumulated in the waste hopper reach a certain degree, the waste hopper may be pulled out of the hood 1 through the waste disposal channel 1201 for treatment. Through setting up recovery cabin 12, the waste material that finishes using can in time be cleared up, prevents that aircraft bonnet 1 is inside to be polluted.
In particular, the fully automatic thromboelastography device also comprises a disinfection device (not shown in the figures); the sterilizing device is arranged at the blending device 9 and is used for sterilizing the blended blood sample.
In this embodiment, the sterilizing device may be electrically connected to the control module, so that the homogenized blood sample on the homogenizing device 9 may be sterilized by high temperature and/or ultraviolet rays under the control of the control module, and the sterilizing operation may be performed simultaneously with the homogenizing operation. Through the disinfection operation, the influence on the subsequent detection result caused by the blood sample being polluted can be avoided.
Specifically, referring to fig. 1 to 5, the fully automatic thromboelastography device further includes a display control panel 15, and the display control panel 15 is disposed on the side wall of the hood 1.
In this embodiment, the display control panel 15 may be electrically connected to the control module, and various related data (such as blending operation duration, activation operation duration, currently performed operation, etc.) during the test process may be transmitted through the control module and displayed on the display control panel 15, so as to help the operator outside the hood 1 to more accurately control the operation condition of the test process. And the display control panel 15 can be used for a worker outside the hood 1 to manually control the on and off of each device in the fully automatic thromboelastography instrument, and can be specifically controlled through buttons and switches, which is not specifically limited in this embodiment. In a specific implementation process, when a worker triggers any button or switch on the display control panel 15, the display control panel 15 sends a corresponding control signal to the control module, and the control module controls the corresponding device to be started or closed after receiving the control signal.
Specifically, referring to fig. 1 to 5, a blood sample inlet 101 facing the blood sample receiving chamber 3 is formed in the side wall of the hood 1, and the full-automatic thromboelastogram apparatus further includes a code scanner 13, wherein the code scanner 13 is disposed at the blood sample inlet 101.
In this embodiment, the scanner 13 may be electrically connected to the control module. All there is the bar code that is used for discernment on each blood sample bottle that awaits measuring, puts a batch of blood sample bottle that awaits measuring into blood sample containing compartment 3 through blood sample entrance 101 at the staff in-process in order to wait for the test, obtains the bar code on the blood sample bottle that awaits measuring and sends control module back through bar code scanner 13, and control module can match final testing result and corresponding blood sample and together export to terminal equipment on, avoids taking place to obscure. Since the code scanner 13 is a conventional one, the operation and principle thereof will not be described herein.
Specifically, referring to fig. 1 to 5, the fully automatic thromboelastography device further includes a data interface 14, the data interface 14 is disposed on the side wall of the hood 1 and electrically connected to the testing device 2, and the data interface 14 is used for externally connecting a terminal device.
In this embodiment, the test data detected by the testing device 2 can be transmitted to a terminal device (e.g., a computer) through the data interface 14 via a data line or a cable, so that the terminal device can analyze the test data to obtain an analysis result of the target blood sample.
Further, referring to fig. 1-9, in an alternative embodiment, the testing apparatus 2 includes a cup holder 205, upper and lower lid assemblies 201, and a drive assembly (not shown); wherein:
the cup holder 205 is used for fixing a target reaction cup, the upper cup cover assembly 201 and the lower cup cover assembly 201 are connected to the driving assembly, the driving assembly is used for driving the upper cup cover assembly 201 and the lower cup cover assembly 201 to move downwards along the direction horizontally close to the cup holder 205, and the driving assembly is used for driving the upper cup cover assembly 201 and the lower cup cover assembly 201 to move upwards along the direction horizontally far away from the cup holder 205;
the upper and lower lid assembly 201 is used for performing lid opening and closing operations on a target cuvette on the cup holder 205.
In this embodiment, the cup holder 205 may be fixed on a working platform inside the hood 1, the target reaction cup (including the cup lid 2052 and the cup body 2051) on the cup holder 205 and the upper and lower cup lid assemblies 201 are arranged at an interval in the horizontal direction, and the upper and lower cup lid assemblies 201 are located above the target reaction cup; the upper and lower cup cover assemblies 201 have a function of fixing the cup covers 2052 on the target cuvette after the upper and lower cup cover assemblies are in contact with the cup covers 2052 of the target cuvette, and the function can be realized by adsorption (provided with an electromagnet or an air pressure device capable of providing adsorption force), clamping (provided with clamping structures which are matched with each other on the cup covers 2052 and the upper and lower cup cover assemblies 201), interference fit and the like. After the cup cover 201 and the upper and lower cup cover assemblies 201 are fixed, the upper and lower cup cover assemblies 201 can drive the cup cover 2052 to move according to a preset track under the driving of the driving assembly, so as to complete the opening and closing operations.
The driving assembly may include a guiding member (e.g., a guiding rail, a sliding groove, etc. disposed in an inclined manner), and a driving device such as a motor, an air cylinder, etc. to drive the upper lid assembly 201 and the lower lid assembly 201 to move along a predetermined inclined direction under the guiding action of the guiding member. When the upper and lower cup cover assemblies 201 move to the position right above the cup holder 205 along the downward-inclined direction, the upper and lower cup cover assemblies 201 can uncover a target reaction cup on the cup holder 205, and then the cup cover 2052 is driven to reset to the upper position along the upward-inclined direction, at this time, the upper and lower cup cover assemblies 201 cannot block the position right above the cup holder 205, and the first sampling needle 803 and the second sampling needle 804 which are positioned right above the cup holder 205 can vertically drop the target reaction cup which is uncovered to inject blood samples and reagents, so that the first sampling needle 803 and the second sampling needle 804 cannot interfere with the upper and lower cup cover assemblies 201, and the structure of the sampling device 8 does not need to be changed to avoid the upper and lower cup cover assemblies 201; after the sample injection is finished, the upper cup lid assembly 201 and the lower cup lid assembly 201 fixed with the cup lids 2052 move to the position right above the cup base 205 along the downward inclined direction again, and the target reaction cups are closed.
Specifically, referring to fig. 1 to 9, the driving assembly includes a first connector 202, a second connector 203, a fixing block 204, and a third driving device 206; wherein:
the third driving device 206 is used for driving the first connecting member 202 to perform vertical lifting movement, the second connecting member 203 is connected to the first connecting member 202 in a sliding manner along the horizontal direction, the upper and lower cup cover assemblies 201 are mounted on the second connecting member 203, a sliding member 2031 is arranged on the second connecting member 203, the fixing block 204 is provided with a first guide groove 2041 which is obliquely arranged, and the sliding member 2031 is in sliding fit with the first guide groove 2041;
when the third driving device 206 drives the first connecting member 202 to descend, the sliding member 2031 slides along the first guide groove 2041 in a downward-inclined direction, and the second connecting member 203 horizontally slides relative to the first connecting member 202 while descending along with the first connecting member 202, so that the upper and lower lid assembly 201 approaches the cup base 205;
when the third driving device 206 drives the first connecting member 202 to ascend, the sliding member 2031 slides along the first guide groove 2041 in an upward-inclining direction, and the second connecting member 203 horizontally slides relative to the first connecting member 202 while ascending along with the first connecting member 202, so that the upper and lower lid assembly 201 is away from the cup holder 205;
the upper and lower lid assembly 201 is used for performing lid opening and closing operations on a target cuvette on the cup holder 205.
In this embodiment, the third driving device 206 may include a motor and a ball screw, a rail slider, etc. coupled thereto, and may also include a linear motion device such as an air cylinder, etc. only the first connecting member 202 is driven to perform a linear up-down reciprocating motion along a direction perpendicular to the working platform, and the specific components are not limited.
The sliding member 2031 may be a roller (when the sliding member 2031 is a roller, the sliding member 2031 is connected to the first guiding groove 2041 in a rolling manner), the fixing block 204 is fixed on the working platform, the first guiding groove 2041 is inclined downward from the direction approaching the cup holder 205 as shown in the figure, when the upper and lower lid assemblies 201 are at the highest point, the sliding member 2031 is located at the uppermost end of the first guide groove 2041 (i.e., the position where the first guide groove 2041 is farthest from the cup holder 205), when the upper and lower cup cover assemblies 201 are located at the lowest point, the sliding member 2031 is located at the lowest end of the first guiding groove 2041 (i.e. the position where the first guiding groove 2041 is closest to the cup holder 205), and the second connecting member 203 can be slidably connected to the first connecting member 202 by way of a rail-and-block connection, and the rail is preferably arranged in a direction parallel to the surface of the workbench and parallel to the direction in which the first guiding groove 2041 is close to or away from the cup holder 205 in the horizontal plane. When the first connecting member 202 is lifted, the upper and lower lid assemblies 201 will move diagonally along the first guiding groove 2041 with the second connecting member 203 due to the limiting effect of the first guiding groove 2041 on the sliding member 2031. When the sliding member 2031 slides to the lowest end of the first guide groove 2041, the upper and lower cup cover assemblies 201 are located right above the cup holder 205, and at this time, the upper and lower cup cover assemblies 201 can perform an uncovering operation or a covering operation on a target reaction cup on the cup holder 205; when the sliding member 2031 slides obliquely upward along the first guide groove 2041 and leaves the lowermost end of the first guide groove 2041, the upper and lower lid assemblies 201 also rise vertically and gradually leave the position right above the cup holder 205 in the horizontal direction, and at this time, the upper and lower lid assemblies 201 no longer block the position right above the cup holder 205.
The complete working process of the upper cup cover device and the lower cup cover device is as follows:
upper and lower cap assembly 201 is at the highest position in the initial state. After the target cuvette is placed on the cuvette holder 205 by the second robot arm 802, the cuvette holder 205 clamps the cup 2051 of the target cuvette; at this time, the third driving device 206 drives the first connecting piece 202 to descend, so that the upper and lower cup lid assemblies 201 move towards the cup base 205 along the inclined direction until contacting with the cup lid 2052 of the target reaction cup, and the cup lid 2052 is grabbed by means of adsorption and the like; then third drive 206 drives first link 202 to rise, and upper and lower lid assembly 201 takes lid 2052 out of cup 2051 and returns to the highest position along the original movement track; after the sample injection in the target reaction cup is finished, the third driving device 206 drives the first connecting piece 202 to descend again, so that the upper and lower cup cover assemblies 201 carrying the cup covers 2052 move towards the cup base 205 again along the inclined direction until the cup covers 2052 are covered on the cup bodies 2051; after the reaction of the sample to be detected in the cup body 2051 is completed, the upper cup cover assembly 201 and the lower cup cover assembly 201 are separated from the cup cover 2052 (the upper cup cover assembly and the lower cup cover assembly can be separated from each other by stopping the air suction action of the air pressure device and powering off the electromagnet), the third driving device 206 drives the first connecting piece 202 to ascend, the upper cup cover assembly 201 and the lower cup cover assembly 201 are reset to the highest position along the original moving track, the second mechanical arm 802 takes the detected target reaction cup away from the cup seat 205 and replaces the new reaction cup, and therefore the next round of cover taking process is continued. Therefore, the upper and lower cup cover assemblies 201 are only located right above the target reaction cup when the cover opening operation and the cover closing operation are performed, and are reset to the highest position along the first guide groove 2041 in other time in the direction away from the reaction cup in an inclined manner, and no blocking is formed right above the target reaction cup, so that after the cover opening operation is completed, a blood sample and a reagent can be injected into the target reaction cup by vertically inserting the first sampling needle 803 and the second sampling needle 804 which are located right above the cup holder 205, and the first sampling needle 803 and the second sampling needle 804 are ensured not to interfere with the upper and lower cup cover assemblies 201, and the use is facilitated.
It should be understood that the present embodiment is not limited to the single upper and lower lid assembly 201, and specifically, as shown in fig. 6 to 8, the cup holder 205, the upper and lower lid assembly 201, the first connecting member 202, the second connecting member 203 and the third driving device 206 may be disposed in two and respectively disposed on the left and right sides of the fixing block 204, so that the two sliding members 2031 can be jointly fitted in one first guiding groove 2041, thereby performing the lid opening operation and the lid closing operation on two target cuvettes simultaneously, and improving the working efficiency. By analogy, in practical application, the upper cup cover assembly 201 and the lower cup cover assembly 201 can be arranged in a plurality of numbers according to needs, so that the functions of simultaneously carrying out cover opening operation and cover closing operation on a plurality of target reaction cups are realized, and the working efficiency is further improved.
Further, referring to fig. 1-11, in an alternative embodiment, upper and lower cap assembly 201 includes a holder 2011, a grasping probe assembly (not shown), and a fourth driver 2014; wherein:
the fixing seat 2011 is installed on the second connecting piece 203, the grabbing probe assembly is connected to the fixing seat 2011 in a sliding mode, the fourth driving device 2014 is connected with the upper end of the grabbing probe assembly, and the fourth driving device 2014 is used for driving the grabbing probe assembly to move up and down relative to the lower end face of the fixing seat 2011;
the lower end face of the fixing seat 2011 is used for abutting against a cup cover 2052 of the target reaction cup, and the lower end of the grabbing probe assembly is used for being in interference fit with a connecting hole 20521 on the cup cover 2052.
In this embodiment, the fourth driving device 2014 may include a motor and a ball screw coupled thereto, or may include a linear motion device such as a cylinder, which only needs to drive the grabbing probe assembly to perform a linear lifting motion along a direction perpendicular to the working platform. The grasping probe assembly may specifically include a metal grasping probe body 2012 having a rod shape. The connecting hole 20521 is a blind hole and is opened in the center of the upper surface of the cup cover 2052, and the cup cover 2052 can be arranged in a T-shaped longitudinal section as shown in fig. 9, so that a sufficient depth position is reserved for the connecting hole 20521 in the center. Since the cap 2052 is usually made of plastic, the metal grasping probe body 2012 can be inserted into the connecting hole 20521 to be in interference fit with the connecting hole 20521, so that the cap 2052 can be lifted from the cup 2051.
In a specific working process, the grabbing probe assembly is at the lowest position (i.e., the state of completely extending out of the lower end face of the fixing seat 2011) in an initial state, the third driving device 206 firstly drives the upper cup cover assembly 201 and the lower cup cover assembly 201 to move downwards to a target reaction cup, so that the lower end of the grabbing probe assembly (i.e., the lower end of the grabbing probe body 2012) is inserted into the connecting hole 20521 of the cup cover 2052, then the third driving device 206 drives the upper cup cover assembly 201 and the lower cup cover assembly 201 to move upwards, and the grabbing probe assembly lifts the cup cover 2052 from the cup body 2051; after the sample injection in the target reaction cup is finished, the third driving device 206 drives the upper cup cover assembly 201 and the lower cup cover assembly 201 to move downwards to the cup body 2051 again until the cup cover 2052 covers the cup body 2051 again and the lower end face of the fixing seat 2011 abuts against the upper end face of the cup cover 2052, at the moment, the fourth driving device 2014 drives the grabbing probe assembly to ascend relative to the fixing seat 2011, the cup cover 2052 cannot ascend along with the grabbing probe assembly under the limiting effect of the lower end face of the fixing seat 2011, so that the grabbing probe assembly can be pulled out of the connecting hole 20521 until the grabbing probe assembly is completely contracted into the fixing seat 2011, and the grabbing probe assembly and the cup cover 2052 are separated; finally, the third driving device 206 drives the upper and lower cap assemblies 201 to move upward, and simultaneously the fourth driving device 2014 drives the grabbing probe assembly to descend to the initial lowest position relative to the fixed seat 2011 to wait for the next cap taking process.
The cover uncovering and uncovering mode adopted by the embodiment is simple in structure, excessive components are not needed, the problems of overlarge sound, unstable structure and short service life when the cover is taken by adopting an electromagnet or an air pressure device are solved, the problem of inconvenience in uncovering when a clamping structure is adopted is solved, the cover uncovering operation and the cover closing operation are simplified, and the operation stability of equipment is improved.
Further, referring to fig. 1-11, in an alternative embodiment, the grasping probe assembly includes a grasping probe body 2012 and a cylindrical guide 2013; wherein:
the cylindrical guide 2013 is in sliding fit with the fixed seat 2011, the fourth driving device 2014 is connected with the upper end of the cylindrical guide 2013, and the fourth driving device 2014 is used for driving the cylindrical guide 2013 to rotate relative to the fixed seat 2011;
the fixing seat 2011 is provided with a limiting through groove 20111 extending in the vertical direction, the lower end face of the cylindrical guide 2013 is provided with an accommodating cavity 20131, the cylindrical surface of the lower end of the cylindrical guide 2013 is provided with a spiral second guide groove 20132, the second guide groove 20132 is communicated with the accommodating cavity 20131, the upper end of the grabbing probe body 2012 is provided with a convex sliding part, the grabbing probe body 2012 is in sliding fit in the accommodating cavity 20131, and the convex sliding part is arranged in the second guide groove 20132 and the limiting through groove 20111 in a penetrating manner;
when the fourth driving device 2014 drives the cylindrical guide 2013 to rotate, the protruding sliding portion slides along the second guide groove 20132 and the limiting through groove 20111, so that the lower end face of the grabbing probe body 2012 moves up and down relative to the fixed seat 2011, and the lower end of the grabbing probe body 2012 is in interference fit with the connecting hole 20521.
In this embodiment, illustratively, the lower extreme of grabbing probe body 2012 is shaft-like and is the metal material, and fourth drive 2014 can be rotating electrical machines, and when fourth drive 2014 drive cylinder guide 2013 rotated for fixing base 2011, protruding sliding part was driven by second guide way 20132 and reciprocated in spacing logical groove 20111 under the limiting displacement who leads to groove 20111 to realized grabbing probe body 2012 reciprocates relative to fixing base 2011 lower terminal surface. When the fourth driving device 2014 drives the cylindrical guide 2013 to rotate in the forward direction, the second guide groove 20132 rises spirally to drive the grabbing probe body 2012 to move upwards; when the fourth driving device 2014 drives the cylindrical guide 2013 to rotate reversely, the second guide groove 20132 is spirally descended to drive the grabbing probe body 2012 to move downwards.
In the specific working process, the grabbing probe body 2012 is at the lowest position in the initial state (i.e., the convex sliding portion is located at the lowest position of the second guide groove 20132, and the grabbing probe body 2012 is in the state of completely extending out of the lower end surface of the fixed seat 2011), the third driving device 206 first drives the upper and lower cup lid assemblies 201 to move downwards to the target cuvette, so that the lower end of the grabbing probe body 2012 is inserted into the connecting hole 20521 of the cup lid 2052, then the third driving device 206 drives the upper and lower cup lid assemblies 201 to move upwards, and the grabbing probe body 2012 lifts the cup lid 2052 from the cup body 2051; after the target reaction cup is filled with samples, the third driving device 206 drives the upper and lower cup cover assemblies 201 to move downwards to the cup body 2051 again until the cup cover 2052 covers the cup body 2051 again and the lower end face of the fixed seat 2011 abuts against the upper end face of the cup cover 2052, at this time, the fourth driving device 2014 drives the cylindrical guide 2013 to rotate forwards, so that the grabbing probe body 2012 rises relative to the fixed seat 2011, and the cup cover 2052 cannot rise along with the grabbing probe body 2012 under the limiting action of the lower end face of the fixed seat 2011, so that the grabbing probe body 2012 can be pulled out from the connecting hole 20521 until the grabbing probe body 2012 is completely contracted into the fixed seat 2011, and the grabbing probe body 2012 is separated from the cup cover 2052; finally, third driving device 206 drives upper and lower cap assembly 201 to move upward, and fourth driving device 2014 drives cylindrical guide 2013 to rotate reversely, so that grabbing probe body 2012 descends to the initial lowest position relative to fixing seat 2011 to wait for the next cap taking process.
This embodiment can realize converting rotary motion into linear motion through the cooperation between second guide way 20132, spacing logical groove 20111 and the protruding sliding part, need not to have saved the space of reserving the linear motion stroke with the help of devices such as ball screw, has simplified spatial structure, has played the deceleration effect simultaneously.
Specifically, referring to fig. 1 to 11, the protruding sliding portion is a connecting bolt 20121, the connecting bolt 20121 sequentially penetrates through the limiting through groove 20111 and the second guide groove 20132 from outside to inside, and the connecting bolt 20121 is in threaded connection with the upper end of the grasping probe body 2012.
Protruding sliding part adopts the mode that detachable bolt connects, the installation and the dismantlement between the fixing base 2011, cylinder guide 2013 and the snatching probe body 2012 of being more convenient for.
It should be noted that other contents of the fully automatic thrombelastogram apparatus disclosed in the present invention can be referred to the prior art, and are not described herein again.
Above only be the utility model discloses an optional embodiment to not consequently restrict the utility model discloses a patent range, all be in the utility model discloses a under the design, utilize the equivalent structure transform of doing of the contents of description and the attached drawing, or direct/indirect application all is included in other relevant technical field the utility model discloses a patent protection within range.

Claims (10)

1. The full-automatic thrombelastogram instrument is characterized by comprising a hood, a three-coordinate driving device, a sampling device, a testing device, a blood sample containing cabin, a reagent containing cabin and a reaction cup containing cabin; wherein:
the three-coordinate driving device, the sampling device, the testing device, the blood sample receiving cabin, the reagent receiving cabin and the reaction cup receiving cabin are all arranged in the hood, and the three-coordinate driving device is connected with the sampling device;
the three-coordinate driving device is used for driving the sampling device to horizontally move and lift above the reaction cup storage cabin, the blood sample storage cabin and the reagent storage cabin; the sampling device is used for grabbing a target reaction cup in the reaction cup receiving cabin onto the testing device under the driving of the three-coordinate driving device, and the sampling device is used for extracting a target blood sample in the blood sample receiving cabin and a target reagent in the reagent receiving cabin and injecting the target blood sample into the target reaction cup under the driving of the three-coordinate driving device;
the testing device is used for carrying out blood sample detection operation on the target reaction cup.
2. The full-automatic thrombelastogram instrument according to claim 1, wherein the three-coordinate driving device comprises a first driving device and a second driving device, the sampling device comprises a first mechanical arm, a second mechanical arm and a sampler, and the full-automatic thrombelastogram instrument further comprises a blending device and an activation cabin; wherein:
the blending device and the activation cabin are both arranged inside the hood;
the first driving device is connected with the first mechanical arm; the first driving device is used for driving the first mechanical arm to grab the target blood sample to the blending device; the blending device is used for blending the target blood sample to obtain a blended blood sample; the target reagent comprises a first reagent and a second reagent, and the first driving device is used for driving the first mechanical arm to grab the first reagent into the activation cabin;
the second driving device is connected with the second mechanical arm and the sampler; the second driving device is used for driving the second mechanical arm to grab the target reaction cup to the testing device; the second driving device is used for driving the sampler to extract the mixed blood sample into the activation cabin, so that the mixed blood sample and the first reagent are activated to obtain an activated blood sample; the second driving device is used for driving the sampler to extract the activated blood sample into the target reaction cup on the testing device; the second driving device is used for driving the sampler to extract the second reagent into the target reaction cup on the testing device.
3. The fully automatic thromboelastography device of claim 2, wherein the sampler comprises a first sampling needle and a second sampling needle; wherein:
the second driving device is used for driving the first sampling needle to extract the mixed blood sample into the activation cabin, so that the mixed blood sample and the first reagent are activated; the second driving device is used for driving the first sampling needle to extract the activated blood sample into the target reaction cup on the testing device; the second driving device is used for driving the second sampling needle to extract the second reagent into the target reaction cup on the testing device.
4. The fully automatic thromboelastography instrument of claim 3, further comprising a washing device; wherein:
the cleaning device is arranged inside the hood and used for cleaning the first sampling needle and the second sampling needle.
5. The fully automatic thromboelastography device of claim 2, further comprising a retrieval compartment; the recovery cabin is arranged in the hood and communicated with the outside of the hood; the first driving device is used for driving the first mechanical arm to grab the extracted activated blood sample and pour the blood sample into the recovery cabin; the second driving device is used for driving the second mechanical arm to grab the detected target reaction cup and pour the target reaction cup into the recovery cabin;
and/or the full-automatic thromboelastography instrument further comprises a disinfection device; the sterilizing device is arranged at the blending device and is used for sterilizing the blended blood sample.
6. The fully automatic thromboelastogram instrument of claim 1, further comprising a display manipulation panel disposed on a side wall of the hood;
and/or a blood sample inlet opposite to the blood sample receiving chamber is formed in the side wall of the hood, the full-automatic thromboelastogram instrument further comprises a code scanner, and the code scanner is arranged at the blood sample inlet;
and/or, the full-automatic thrombelastogram appearance still includes data interface, data interface set up in on the lateral wall of aircraft bonnet and with the testing arrangement electricity is connected, and data interface is used for external terminal equipment.
7. The fully automatic thromboelastogram instrument of claim 1, wherein the testing device comprises a cup holder, upper and lower cup cover assemblies and a drive assembly; wherein:
the cup seat is used for fixing the target reaction cup, the upper cup cover assembly and the lower cup cover assembly are connected to the driving assembly, the driving assembly is used for driving the upper cup cover assembly and the lower cup cover assembly to move downwards along the direction of horizontally approaching the cup seat, and the driving assembly is used for driving the upper cup cover assembly and the lower cup cover assembly to move upwards along the direction of horizontally departing from the cup seat;
the upper cup cover assembly and the lower cup cover assembly are used for carrying out cover opening operation and cover closing operation on the target reaction cup on the cup seat.
8. The fully automatic thromboelastography instrument of claim 7, wherein the drive assembly comprises a first connector, a second connector, a fixed block, and a third drive device; wherein:
the third driving device is used for driving the first connecting piece to do vertical lifting motion, the second connecting piece is connected to the first connecting piece in a sliding mode along the horizontal direction, the upper cup cover assembly and the lower cup cover assembly are mounted on the second connecting piece, a sliding piece is arranged on the second connecting piece, the fixing block is provided with a first guide groove which is arranged in an inclined mode, and the sliding piece is matched in the first guide groove in a sliding mode;
when the third driving device drives the first connecting piece to descend, the sliding piece slides along the first guide groove in the downward inclined direction, and the second connecting piece horizontally slides relative to the first connecting piece while descending along with the first connecting piece, so that the upper cup cover assembly and the lower cup cover assembly are close to the cup base;
when the third driving device drives the first connecting piece to ascend, the sliding piece slides along the direction that the first guide groove inclines upwards, and the second connecting piece horizontally slides relative to the first connecting piece while ascending along with the first connecting piece so as to enable the upper cup cover assembly and the lower cup cover assembly to be far away from the cup base.
9. The fully automatic thromboelastogram instrument of claim 8, wherein the upper and lower cup cover assemblies comprise a fixing base, a gripping probe assembly and a fourth driving device; wherein:
the fixed seat is arranged on the second connecting piece, the grabbing probe assembly is connected to the fixed seat in a sliding mode, the fourth driving device is connected with the upper end of the grabbing probe assembly, and the fourth driving device is used for driving the grabbing probe assembly to move up and down relative to the lower end face of the fixed seat;
the lower end face of the fixing seat is used for abutting against the cup cover of the target reaction cup, and the lower end of the grabbing probe assembly is used for being in interference fit with the connecting hole in the cup cover.
10. The fully automated thromboelastography instrument of claim 9, wherein the grasping probe assembly comprises a grasping probe body and a cylindrical guide; wherein:
the cylinder guide piece is in sliding fit with the fixed seat, the fourth driving device is connected with the upper end of the cylinder guide piece, and the fourth driving device is used for driving the cylinder guide piece to rotate relative to the fixed seat;
the fixed seat is provided with a limiting through groove extending in the vertical direction, the lower end face of the cylindrical guide piece is provided with an accommodating cavity, a spiral second guide groove is formed in the cylindrical surface of the lower end of the cylindrical guide piece and communicated with the accommodating cavity, a protruding sliding part is arranged at the upper end of the grabbing probe body, the grabbing probe body is in sliding fit in the accommodating cavity, and the protruding sliding part penetrates through the second guide groove and the limiting through groove;
when the fourth driving device drives the cylindrical guide piece to rotate, the protruding sliding part slides along the second guide groove and the limiting through groove, so that the grabbing probe body moves up and down relative to the lower end face of the fixing seat, and the lower end of the grabbing probe body is in interference fit with the connecting hole.
CN202220623696.3U 2021-11-18 2022-03-21 Full-automatic thrombelastogram instrument Active CN217466952U (en)

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