CN115501789B - 一种辅酶q10的提纯设备 - Google Patents
一种辅酶q10的提纯设备 Download PDFInfo
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- CN115501789B CN115501789B CN202211184816.5A CN202211184816A CN115501789B CN 115501789 B CN115501789 B CN 115501789B CN 202211184816 A CN202211184816 A CN 202211184816A CN 115501789 B CN115501789 B CN 115501789B
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- ACTIUHUUMQJHFO-UHFFFAOYSA-N Coenzym Q10 Natural products COC1=C(OC)C(=O)C(CC=C(C)CCC=C(C)CCC=C(C)CCC=C(C)CCC=C(C)CCC=C(C)CCC=C(C)CCC=C(C)CCC=C(C)CCC=C(C)C)=C(C)C1=O ACTIUHUUMQJHFO-UHFFFAOYSA-N 0.000 title claims abstract description 16
- 235000017471 coenzyme Q10 Nutrition 0.000 title claims abstract description 16
- ACTIUHUUMQJHFO-UPTCCGCDSA-N coenzyme Q10 Chemical compound COC1=C(OC)C(=O)C(C\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(/C)CCC=C(C)C)=C(C)C1=O ACTIUHUUMQJHFO-UPTCCGCDSA-N 0.000 title claims abstract description 16
- 229940110767 coenzyme Q10 Drugs 0.000 title claims abstract description 15
- 238000000746 purification Methods 0.000 title claims description 6
- 238000005192 partition Methods 0.000 claims description 8
- 230000005540 biological transmission Effects 0.000 claims description 3
- 230000008878 coupling Effects 0.000 claims description 2
- 238000010168 coupling process Methods 0.000 claims description 2
- 238000005859 coupling reaction Methods 0.000 claims description 2
- 230000002093 peripheral effect Effects 0.000 claims description 2
- 229920000114 Corrugated plastic Polymers 0.000 claims 1
- 239000000463 material Substances 0.000 claims 1
- 239000007788 liquid Substances 0.000 abstract description 39
- 239000011259 mixed solution Substances 0.000 abstract description 11
- 238000000034 method Methods 0.000 abstract description 9
- 230000008569 process Effects 0.000 abstract description 6
- 238000000926 separation method Methods 0.000 abstract description 3
- 239000000243 solution Substances 0.000 description 5
- 230000000694 effects Effects 0.000 description 4
- 238000002156 mixing Methods 0.000 description 4
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 4
- 210000004027 cell Anatomy 0.000 description 3
- AZQWKYJCGOJGHM-UHFFFAOYSA-N para-benzoquinone Natural products O=C1C=CC(=O)C=C1 AZQWKYJCGOJGHM-UHFFFAOYSA-N 0.000 description 3
- GVJHHUAWPYXKBD-UHFFFAOYSA-N (±)-α-Tocopherol Chemical compound OC1=C(C)C(C)=C2OC(CCCC(C)CCCC(C)CCCC(C)C)(C)CCC2=C1C GVJHHUAWPYXKBD-UHFFFAOYSA-N 0.000 description 2
- 230000002708 enhancing effect Effects 0.000 description 2
- 230000004048 modification Effects 0.000 description 2
- 238000012986 modification Methods 0.000 description 2
- 235000016709 nutrition Nutrition 0.000 description 2
- 239000000047 product Substances 0.000 description 2
- 238000007127 saponification reaction Methods 0.000 description 2
- 239000000126 substance Substances 0.000 description 2
- 206010003210 Arteriosclerosis Diseases 0.000 description 1
- 208000024172 Cardiovascular disease Diseases 0.000 description 1
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 1
- 229930003427 Vitamin E Natural products 0.000 description 1
- 229930003448 Vitamin K Natural products 0.000 description 1
- 230000004913 activation Effects 0.000 description 1
- 230000032683 aging Effects 0.000 description 1
- 239000003513 alkali Substances 0.000 description 1
- 239000003963 antioxidant agent Substances 0.000 description 1
- 230000003078 antioxidant effect Effects 0.000 description 1
- 235000006708 antioxidants Nutrition 0.000 description 1
- 208000011775 arteriosclerosis disease Diseases 0.000 description 1
- 239000002585 base Substances 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 208000015606 cardiovascular system disease Diseases 0.000 description 1
- 238000004440 column chromatography Methods 0.000 description 1
- 239000002537 cosmetic Substances 0.000 description 1
- 238000002425 crystallisation Methods 0.000 description 1
- 230000008025 crystallization Effects 0.000 description 1
- 238000010586 diagram Methods 0.000 description 1
- 235000015872 dietary supplement Nutrition 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 238000000855 fermentation Methods 0.000 description 1
- 230000004151 fermentation Effects 0.000 description 1
- 235000013305 food Nutrition 0.000 description 1
- WIGCFUFOHFEKBI-UHFFFAOYSA-N gamma-tocopherol Natural products CC(C)CCCC(C)CCCC(C)CCCC1CCC2C(C)C(O)C(C)C(C)C2O1 WIGCFUFOHFEKBI-UHFFFAOYSA-N 0.000 description 1
- 230000036541 health Effects 0.000 description 1
- 238000010438 heat treatment Methods 0.000 description 1
- 230000036039 immunity Effects 0.000 description 1
- 238000011031 large-scale manufacturing process Methods 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 230000035764 nutrition Effects 0.000 description 1
- 239000003960 organic solvent Substances 0.000 description 1
- 230000003647 oxidation Effects 0.000 description 1
- 238000007254 oxidation reaction Methods 0.000 description 1
- SHUZOJHMOBOZST-UHFFFAOYSA-N phylloquinone Natural products CC(C)CCCCC(C)CCC(C)CCCC(=CCC1=C(C)C(=O)c2ccccc2C1=O)C SHUZOJHMOBOZST-UHFFFAOYSA-N 0.000 description 1
- 210000002706 plastid Anatomy 0.000 description 1
- -1 quinone compound Chemical class 0.000 description 1
- 239000002994 raw material Substances 0.000 description 1
- NPCOQXAVBJJZBQ-UHFFFAOYSA-N reduced coenzyme Q9 Natural products COC1=C(O)C(C)=C(CC=C(C)CCC=C(C)CCC=C(C)CCC=C(C)CCC=C(C)CCC=C(C)CCC=C(C)CCC=C(C)CCC=C(C)C)C(O)=C1OC NPCOQXAVBJJZBQ-UHFFFAOYSA-N 0.000 description 1
- 238000010898 silica gel chromatography Methods 0.000 description 1
- 238000000638 solvent extraction Methods 0.000 description 1
- 238000000967 suction filtration Methods 0.000 description 1
- 229940035936 ubiquinone Drugs 0.000 description 1
- 238000001291 vacuum drying Methods 0.000 description 1
- 235000019165 vitamin E Nutrition 0.000 description 1
- 229940046009 vitamin E Drugs 0.000 description 1
- 239000011709 vitamin E Substances 0.000 description 1
- 235000019168 vitamin K Nutrition 0.000 description 1
- 239000011712 vitamin K Substances 0.000 description 1
- 150000003721 vitamin K derivatives Chemical class 0.000 description 1
- 229940046010 vitamin k Drugs 0.000 description 1
Images
Classifications
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F27/00—Mixers with rotary stirring devices in fixed receptacles; Kneaders
- B01F27/80—Mixers with rotary stirring devices in fixed receptacles; Kneaders with stirrers rotating about a substantially vertical axis
- B01F27/92—Mixers with rotary stirring devices in fixed receptacles; Kneaders with stirrers rotating about a substantially vertical axis with helices or screws
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F31/00—Mixers with shaking, oscillating, or vibrating mechanisms
- B01F31/44—Mixers with shaking, oscillating, or vibrating mechanisms with stirrers performing an oscillatory, vibratory or shaking movement
- B01F31/441—Mixers with shaking, oscillating, or vibrating mechanisms with stirrers performing an oscillatory, vibratory or shaking movement performing a rectilinear reciprocating movement
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F35/00—Accessories for mixers; Auxiliary operations or auxiliary devices; Parts or details of general application
- B01F35/30—Driving arrangements; Transmissions; Couplings; Brakes
- B01F35/32—Driving arrangements
- B01F35/32005—Type of drive
- B01F35/32015—Flow driven
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F35/00—Accessories for mixers; Auxiliary operations or auxiliary devices; Parts or details of general application
- B01F35/71—Feed mechanisms
- B01F35/717—Feed mechanisms characterised by the means for feeding the components to the mixer
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F35/00—Accessories for mixers; Auxiliary operations or auxiliary devices; Parts or details of general application
- B01F35/90—Heating or cooling systems
- B01F35/92—Heating or cooling systems for heating the outside of the receptacle, e.g. heated jackets or burners
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C46/00—Preparation of quinones
- C07C46/10—Separation; Purification; Stabilisation; Use of additives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C50/00—Quinones
- C07C50/26—Quinones containing groups having oxygen atoms singly bound to carbon atoms
- C07C50/28—Quinones containing groups having oxygen atoms singly bound to carbon atoms with monocyclic quinoid structure
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- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Extraction Or Liquid Replacement (AREA)
Abstract
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CN202211184816.5A CN115501789B (zh) | 2022-09-27 | 2022-09-27 | 一种辅酶q10的提纯设备 |
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CN202211184816.5A CN115501789B (zh) | 2022-09-27 | 2022-09-27 | 一种辅酶q10的提纯设备 |
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CN115501789A CN115501789A (zh) | 2022-12-23 |
CN115501789B true CN115501789B (zh) | 2023-07-14 |
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CN116571194B (zh) * | 2023-04-20 | 2023-12-15 | 浙江度森光伏科技有限公司 | 一种单晶硅制绒添加剂生产用反应装置及使用方法 |
Citations (2)
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JP6353936B1 (ja) * | 2017-01-31 | 2018-07-04 | 株式会社金星 | ファインバブル発生装置 |
CN109387054A (zh) * | 2018-09-20 | 2019-02-26 | 大连理工大学 | 一种立式行星差速绞龙混合搅拌烘干机和方法 |
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JPH0634943B2 (ja) * | 1989-05-15 | 1994-05-11 | 動力炉・核燃料開発事業団 | 遠心抽出器用分離ロータ |
US5254076A (en) * | 1992-08-06 | 1993-10-19 | Arch Development Corporation | Centrifugal pyrocontactor |
KR101259907B1 (ko) * | 2003-04-11 | 2013-05-02 | 홍상헌 | 다중 원판형 슬러지 농축장치 |
CN110876858A (zh) * | 2019-12-24 | 2020-03-13 | 苏州增华新能源科技有限公司 | 一种具有搅拌混合进料功能的离心萃取机 |
CN110876859A (zh) * | 2019-12-24 | 2020-03-13 | 苏州增华新能源科技有限公司 | 一种消除共振现象的离心萃取机 |
CN112755588A (zh) * | 2021-01-13 | 2021-05-07 | 常州机电职业技术学院 | 一种基于生物制药用的萃取离心混合系统及其离心方法 |
CN214861375U (zh) * | 2021-01-27 | 2021-11-26 | 云南德瑞油脂有限公司 | 一种纯物理提取脂肪酸的设备 |
CN216295810U (zh) * | 2021-10-08 | 2022-04-15 | 济宁市岳威化工有限公司 | 一种增稠剂的乳化装置 |
CN113694564B (zh) * | 2021-11-01 | 2022-01-18 | 苏州永诺泓泽生物科技有限公司 | 一种生物化工用萃取机 |
CN114377608A (zh) * | 2021-12-30 | 2022-04-22 | 苏州爱得华塑化有限公司 | 一种生产充电桩电缆保护套用的原料搅拌机 |
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JP6353936B1 (ja) * | 2017-01-31 | 2018-07-04 | 株式会社金星 | ファインバブル発生装置 |
CN109387054A (zh) * | 2018-09-20 | 2019-02-26 | 大连理工大学 | 一种立式行星差速绞龙混合搅拌烘干机和方法 |
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Denomination of invention: A purification equipment for coenzyme Q10 Effective date of registration: 20231215 Granted publication date: 20230714 Pledgee: Zhejiang Tongxiang Rural Commercial Bank Co.,Ltd. Wuzhen sub branch Pledgor: WEISHI BIOTECHNOLOGY Co.,Ltd. Registration number: Y2023980071561 |
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Granted publication date: 20230714 Pledgee: Zhejiang Tongxiang Rural Commercial Bank Co.,Ltd. Wuzhen sub branch Pledgor: WEISHI BIOTECHNOLOGY Co.,Ltd. Registration number: Y2023980071561 |