CN115463187A - Application of anticancer composition in preparation of medicine for treating cancer - Google Patents

Abstract

The invention provides an anticancer composition and a preparation method and application thereof, belonging to the technical field of medicines and preparation thereof, wherein the anticancer composition comprises the following raw materials in parts by weight: 10 to 20 portions of pseudo-ginseng, 20 to 60 portions of dandelion, 5 to 15 portions of Yunnan manyleaf paris rhizome, 5 to 15 portions of ginseng, 5 to 15 portions of astragalus root and 10 to 20 portions of ganoderma lucidum spore, and the raw materials are crushed and uniformly mixed to prepare particles. The anticancer composition can effectively treat various cancers, including breast cancer, leukemia, esophagus cancer, lung cancer, gastric cancer, primary liver cancer, pancreatic cancer, colorectal cancer, cervical cancer and ovarian cancer.

Description

Application of anticancer composition in preparation of medicine for treating cancer

The application is a divisional application named 'an anticancer drug and a preparation method thereof' with the application date of 2018, 08 and 24 months and the application number of 201810974838.9.

Technical Field

The invention belongs to the technical field of medicines and preparation thereof, and particularly relates to an anticancer medicine and a preparation method thereof.

Background

In disease death, the malignant tumor accounts for 22.7 percent, the cerebrovascular disease accounts for 22.63 percent and the respiratory system disease accounts for 14.02 percent, so that the cancer becomes a serious threat to the health of people and becomes a first killer.

Pseudo-ginseng: the specific rare medicinal materials in Yunnan province, the common active ingredients of the materials are ginsenoside and unique notoginsenoside R2, which have the functions of promoting blood circulation, removing blood stasis, inhibiting tumor cells and inducing tumor cell apoptosis. The fact proves that: notoginsenoside has effects in improving vascular endothelium, reducing blood viscosity, and inhibiting platelet activation and aggregation, and has antithrombotic, antitumor thrombosis, and antitumor metastasis effects. Therefore, the anticancer drugs are the first to be introduced to san Qi.

Dandelion: the herba Taraxaci has effects of clearing away heat and toxic materials, relieving pain, resolving hard mass, promoting diuresis, and relieving swelling. Team research in the Canadian center for cancer treatment, seyan, pandy, a leading scientist at the university of Windsor, demonstrated that the Dandelion root extract killed 98% of the cancer cells in 48 hours. After the cancer cells are killed, healthy cells appear. The dandelion has good treatment effect on leukemia, breast cancer, colon cancer, prostatic cancer, liver cancer and lung cancer. The research result has great significance for treating cancers.

Yunnan paris polyphylla: rhizoma paridis Yunnanensis is a special medicinal material in Yunnan, also called paris polyphylla, and is a plant of rhizoma paridis in the family of Hemiseraceae. The paris polyphylla has the effects of clearing heat and removing toxicity, and relieving swelling and pain, and the modern pharmaceutical research finds that the paris polyphylla can activate antibody immunity, promote antibody formation and enhance the phagocytic capacity of white blood cells, has stronger anticancer effect, can inhibit the growth of tumor cells, has very strong killing effect on the formed tumor cells, can destroy the cell structure of the formed tumor cells and promote the apoptosis metabolism of the formed tumor cells. The traditional Chinese medicine composition is mainly used for treating gastric cancer, liver cancer, lung cancer, leukemia, malignant lymphoma and the like in clinic.

Ginseng: ginseng is Araliaceae, and mainly produced in Jilin, liaoning and Heilongjiang. Sweet in nature and taste, slightly bitter, entering spleen and lung heart meridians. It has the functions of invigorating primordial qi, nourishing lung and spleen, promoting fluid production and tranquilizing. People are terrorised and desperate after suffering from cancer, especially need to tonify qi, relieve exhaustion, enhance immunity and prevent cancer cells from spreading and transferring, and ginseng plays the roles of consolidating body resistance, strengthening body resistance and pressing healthy energy against pathogens.

Astragalus root: astragalus membranaceus is a perennial herb of the family Viciaceae, produced in Shanxi and inner Mongolia places, has sweet nature and taste, and slightly warms and enters spleen and lung channels. Has the effects of invigorating qi, invigorating yang, consolidating superficial resistance, arresting sweating, promoting granulation, inducing diuresis, and relieving swelling. Radix astragali is a vital adjuvant medicine for treating cancer.

Ganoderma lucidum: the ganoderma must be Yunnan plateau ganoderma (wall-broken spore powder), commonly called as 'immortal grass'. Ganoderma contains organic germanium, and has effects of tonifying, strengthening body constitution, strengthening body resistance, and promoting health. In particular, the high molecular polysaccharide contained in the ganoderma lucidum can promote the synthesis of proteins, DNA and RNA of organisms, promote the division and proliferation of cells, stimulate the nonspecific resistance and the immune specific immune response of human bodies, inhibit the generation of tumor physiological active compounds, strengthen the immune system of the human bodies and improve the efficacy of resistance to diseases, so the anti-cancer effect is particularly remarkable.

The antineoplastic medicine can be divided into five types, namely plant alkaloid and other natural medicines, antineoplastic antibiotic and related substances, alkylating agent, antimetabolite and other antineoplastic medicines, most of the prior art has complex preparation process and high preparation cost, and the prepared medicine has large side effect, for example, chinese invention application 201510996205.4 discloses a high molecular compound with anticancer activity, a preparation method and application thereof.

Therefore, how to overcome the above technical problems becomes a technical problem to be solved urgently by those skilled in the art.

Disclosure of Invention

In order to solve the defects of complex manufacturing process and high manufacturing cost in the prior art, the invention introduces an anti-cancer medicament and a preparation method thereof.

An anticancer drug comprises the following components in parts by weight: 10 to 20 portions of pseudo-ginseng, 20 to 60 portions of dandelion, 5 to 15 portions of Yunnan manyleaf paris rhizome, 5 to 15 portions of ginseng, 5 to 15 portions of astragalus and 10 to 20 portions of ganoderma lucidum spore.

Preferably, the components and the parts by weight of the components are as follows: 12 to 18 portions of pseudo-ginseng, 30 to 50 portions of dandelion, 7 to 12 portions of Yunnan manyleaf paris rhizome, 7 to 13 portions of ginseng, 7 to 13 portions of astragalus and 12 to 18 portions of ganoderma lucidum spore.

Preferably, the components and the parts by weight of the components are as follows: 15 parts of pseudo-ginseng, 40 parts of dandelion, 10 parts of paris polyphylla, 10 parts of ginseng, 10 parts of astragalus membranaceus and 15 parts of ganoderma lucidum spores.

Preferably, the pseudo-ginseng is the cut part of the pseudo-ginseng.

Preferably, the dandelion is root of dandelion.

Preferably, the ganoderma lucidum is Yunnan plateau ganoderma lucidum.

The preparation method of the anticancer drug comprises the following preparation steps:

s1: pulverizing Notoginseng radix, herba Taraxaci, rhizoma paridis Yunnanensis, ginseng radix and radix astragali to no less than 40 mesh, breaking cell wall of Ganoderma spore with ultrafine pulverizer, and pulverizing to no less than 1200 mesh;

s2: mixing powders of Notoginseng radix, herba Taraxaci, rhizoma paridis Yunnanensis, ginseng radix, radix astragali and Ganoderma spore at a certain proportion, and granulating in a swing granulator;

preferably, the method further comprises the step S-1: the pseudo-ginseng, the dandelion, the paris polyphylla, the ginseng, the astragalus mongholicus and the ganoderma lucidum spores are air-dried until the moisture content of the pseudo-ginseng, the dandelion, the paris polyphylla, the ginseng, the astragalus mongholicus and the ganoderma lucidum spores is 5-7%.

Preferably, the method further comprises the step S-2: selecting pseudo-ginseng, dandelion, paris polyphylla, ginseng, astragalus and ganoderma lucidum spores, wherein the selection conditions are as follows: the total content of R1, rg1 and Rb1 saponins in the pseudo-ginseng is more than or equal to 15.5 percent, the content of caffeic acid in the dandelion is more than or equal to 0.020 percent, the total content of rhizoma paridis saponin I, rhizoma paridis saponin II, rhizoma paridis saponin III and rhizoma paridis saponin IV in the Yunnan rhizoma paridis is more than or equal to 0.6 percent, the total content of ginsenoside Rg1 and ginsenoside Re in the ginseng is more than or equal to 0.03 percent, the content of astragaloside IV in the astragalus root is more than or equal to 0.04 percent, the content of calycosin glucoside is more than or equal to 0.02 percent, and the content of ganoderma lucidum polysaccharide in the ganoderma lucidum is more than or equal to 0.5 percent.

The invention also provides application of the anti-cancer composition in the technical scheme in preparation of anti-cancer drugs.

Preferably, the anticancer composition is applied to the preparation of medicaments for treating breast cancer.

Preferably, the anticancer composition is applied to the preparation of drugs for treating leukemia.

Preferably, the anticancer composition is applied to the preparation of the medicine for treating the esophagus cancer.

Preferably, the anticancer composition is applied to the preparation of a medicament for treating lung cancer.

Preferably, the anticancer composition is applied to the preparation of a medicine for treating gastric cancer.

Preferably, the anticancer composition is applied to the preparation of a medicament for treating primary liver cancer.

Preferably, the anticancer composition is applied to the preparation of medicines for treating pancreatic cancer.

Preferably, the anticancer composition is applied to the preparation of medicines for treating colorectal cancer.

Preferably, the anticancer composition is applied to the preparation of a medicine for treating cervical cancer.

Preferably, the anticancer composition is applied to the preparation of medicines for treating ovarian cancer.

The medicine prepared by the invention can effectively treat cancers, has simpler preparation process and lower cost compared with other medicines for treating cancers, and has the effects of strengthening body resistance, consolidating the constitution, promoting blood circulation, removing blood stasis, reducing swelling, resolving masses and the like: (1) supporting and consolidating the constitution: ginseng, ganoderma, etc. not only can improve cellular immunity, but also can increase lymphocyte ratio. By improving the cellular immune function, the immune monitoring function on cancer cells entering the circulation is exerted, and the attacking ability of T lymphocytes is improved, so that the cancer cells lose the transferring ability and are disintegrated. The biological reaction regulating effect of Ginseng radix and radix astragali in tonifying medicine can induce the release of cytokine and tumor inhibiting factor, promote lymphocyte metastasis, and improve cancer killing ability, so as to kill cancer cells during operation; (2) promoting blood circulation by removing blood stasis: the main effects of pseudo-ginseng are promoting blood circulation to remove blood stasis, softening enclosed mass and dissipating cancer and swelling. The blood viscosity is closely related to the tumor metastasis, and many links of cancer cell metastasis are related to the high blood coagulation state. Promoting blood circulation for removing blood stasis has anticoagulant and fibrinolysin activating effects, can improve blood diffusion and metastasis of malignant tumor patients, and can also play a role in anti-metastasis by inhibiting proliferation of cancer cells; (3) eliminating swelling and dissipating stagnation: the dandelion, the paris polyphylla and the contained effective components can directly kill cancer cells and prevent the diffusion and the metastasis of the cancer cells, and are key components of the invention. A large number of clinical verifications prove that the dandelion and the paris polyphylla have important functions of detoxification, detumescence and stagnation elimination of cancer.

Detailed Description

The following examples are intended to illustrate the invention, but not to limit the scope of the invention.

Example one

The embodiment provides an anticancer drug and a preparation method thereof, wherein the preparation method comprises the following steps:

1. selecting: the method comprises the following steps of selecting pseudo-ginseng, dandelion, paris polyphylla, ginseng, astragalus and ganoderma lucidum spores, wherein after the selection is finished, the total content of R1, rg1 and Rb1 in the pseudo-ginseng is more than or equal to 15.5 percent, the content of caffeic acid in dandelion is more than or equal to 0.020 percent, the total content of paris polyphylla saponin I, paris polyphylla saponin II, paris polyphylla saponin III and paris polyphylla saponin IV in the paris polyphylla is more than or equal to 0.6 percent, the total content of ginsenoside Rg1 and ginsenoside Re in the ginseng is more than or equal to 0.03 percent, the content of astragaloside in the astragalus is more than or equal to 0.04 percent, the content of calycosin glucoside is more than or equal to 0.02 percent, and the content of ganoderma lucidum polysaccharide in the ganoderma lucidum is more than or equal to 0.5 percent;

2. cleaning: cleaning Notoginseng radix, herba Taraxaci, rhizoma paridis Yunnanensis, ginseng radix, radix astragali and Ganoderma spore with cleaning machine (model WQ-112 of Shanghai Taiming mechanical Co., ltd.);

3. air drying: drying pseudo-ginseng, dandelion, paris polyphylla, ginseng, astragalus and ganoderma lucidum spores by using a vacuum drying oven until the moisture of the pseudo-ginseng, the dandelion, the paris polyphylla, the ginseng, the astragalus and the ganoderma lucidum spores is 5-7 percent;

4. crushing: pulverizing Notoginseng radix, herba Taraxaci, rhizoma paridis Yunnanensis, ginseng radix and radix astragali to no less than 40 mesh, breaking cell wall of Ganoderma spore with ultrafine pulverizer (model of WKE-1 of Sinkiang mechanical company, cinesota chinensis) to no less than 1200 mesh;

5. metering, preparing and mixing: uniformly mixing the components by using a stainless steel stirring tank (model BXP-5 of Nanjing Teng Yang equipment factory) according to the following weight parts: 10 parts of pseudo-ginseng, 20 parts of dandelion, 5 parts of paris polyphylla, 5 parts of ginseng, 5 parts of astragalus and 10 parts of ganoderma lucidum spores;

6. and (3) granulating: granulating the mixed medicine in a swing granulator (model of HK-88 of Jingcheng medical equipment, inc. of Qingzhou, shandong);

7. and packaging and delivering after quality inspection.

Example two

In this embodiment, except the step 5, the components are mixed according to the weight ratio: 20 parts of pseudo-ginseng, 60 parts of dandelion, 15 parts of paris polyphylla, 15 parts of ginseng, 15 parts of astragalus membranaceus and 20 parts of ganoderma lucidum spores.

EXAMPLE III

In the embodiment except the step 5, the components are mixed according to the weight portion: 15 parts of pseudo-ginseng, 40 parts of dandelion, 10 parts of paris polyphylla, 10 parts of ginseng, 10 parts of astragalus mongholicus and 15 parts of ganoderma lucidum spores.

Example four

The cases of taking the medicine prepared by the invention are as follows:

1. breast cancer

Patient one, female, 62 years old, theory of the university. The patient had left mastectomy for 2 years, now a 3X 2 cm square mass was found in the right breast and mucinous adenocarcinoma cells were visible on pathological examination. Patient's mood 24722nd, chest and hypochondrium stuffiness and pain, poor appetite, wiry pulse and thin and yellow tongue coating.

After the medicine is orally taken for more than 30 days, the symptoms are improved, the packet size is reduced to the size of the broad beans, and the breast packet disappears after more than 60 days. After the medicine is taken for 180 days, the curative effect is consolidated, the current state of illness is completely controlled, and the body is basically recovered.

2. Leukemia (leukemia)

Patient two, male, age 20, farmer, aspergillus. The patient is confirmed to be treated by admission of acute lymphocytic leukemia through bone puncture, and the diagnosis is as follows: dizziness, tinnitus, palpitation, shortness of breath, lassitude, tastelessness, poor appetite, abdominal distension, sometimes loose stools, lumbago, soreness of the knees, cough, white sputum, white lips, pale tongue with white coating, deep, thready and rapid pulse. Blood pressure 14.7/9.3KPa, white blood cell 3.6 × 10/L red blood cell 1.29 × 10L, hemoglobin 35g/L, and blood platelet 110 × 10L.

Because of difficult economic discharge, the patients can take the medicine for 3 months, the face of the patients is ruddy, and the patients can participate in labor, and the subjective condition is good. Checking 3.8X 10/L of white blood cells, 2.9X 10/L of red blood cells, 80g/L of hemoglobin and 45X 10 of platelets, and then continuing to take the medicine.

Patient three, male, 44, zhaotong, diagnosis of 23 months 9, patient with fever, non-stop epistaxis, chronic granulocytic leukemia, hemogram as diagnosed by bone marrow examination in local hospital: 15.6L of white blood cells, 5% of immature cells, 80L of hemoglobin and 360% of platelets. Bone marrow elephant: the proliferation of nucleated cells is obviously active, the number of granulocytes is obviously increased, and the number of alkaline granulocytes accounting for 38 percent of the number of the basic granulocytes is also obviously increased mainly in the middle and late juvenile stages. The hyperplasia of the red system and the lymphatic system is obviously inhibited. Two pieces of megakaryocytes were observed with at most one 134 clustered platelets visible.

After the patient takes the medicine for 1 year, the symptoms are obviously improved, and the number of the juvenile cells in the peripheral blood is reduced to 2 percent. The patient is subjected to a double-examination. The complexion is ruddy, the spirit is improved, the peripheral hemogram is basically in a normal range, the symptom is stable all the time, and the portable labor can be participated.

3. Esophageal cancer

Patients who are male, 71, chuxiong, have hematemesis for more than 1 year due to dysphagia and chest and bone pain. The infiltration type cancer (5 cm range) at the lower part of the esophagus is detected by gastroscopy, and cancer cells are found by esophagus biopsy.

After the medicine is taken for 4 months, the symptoms disappear, and the patient eats the medicine for 2 years and is like a regular person. Then the patient keeps eating as usual, still in eight years old, activity and activity. For many years, cancer cells have not spread and metastasized and the body has recovered.

4. Lung cancer

Patients with male and female 51 Kunming who have dry cough, chest pain 10, palpitation, insomnia, and edge lung cancer after taking photos and lung CT.

After the medicine is taken for 6 days, the symptoms are obviously improved. The focus of infection is slightly smaller and the margin is intact. After the taking of the tablets for a plurality of times, the focus is stable, no metastasis occurs, and the tumor-bearing survival has been carried out for more than 2 years through follow-up and self-care of life.

Patient six, female, 56, farmer, yuxi, patient exam: pale and superficial face, emaciation, low speech, hoarseness, severe pain of chest and pedicle compression, concave edema of lower limbs, sunken, astringent, thin and weak two pulses, purple dark tongue, purple ecchymosis on both sides, little coating, purple dark and varicose sublingual veins. The clinical hospital laboratory examines the hemoglobin 105, the white blood cells 7.6/L and the neutrophil 67, the lymphocyte 67 and the lymphocyte 33 mm/h. Except for lung cancer on the left side of the chest radiograph, pleural effusion. Hospital filming and tomography reports: it is suitable for left lung central type lung cancer. The atelectasis is accompanied with the change of effusion, the pathological examination is bloody pleural effusion, and a plurality of lung cancer cells are found. The disease belongs to the late stage and can not be operated or treated by radiotherapy, so the traditional Chinese medicine treatment is carried out. When the mitomycin intravenous drip is intermittently applied and the medicine is stopped because of vomiting caused by toxic and side effects and no food intake, the back of a patient is slightly painful, the patient has better asthma and physical strength, the body weight of the patient is increased by 1 kg after the medicine is taken for 60 days, and the patient is reviewed in a hospital and reported by an X-ray: the focus of the left lung central cancer is reduced. Left pleural effusion decreased and left lung lobes enlarged (lungs already distended). After taking the medicine for 30 days, the X-ray finger film rechecks the reduction of the lung tumor, most of left pleural effusion is eliminated, and the expansion of the left lung lobe is obviously improved compared with the former.

5. Stomach cancer

Seven patients, male, 54, kunming, dull pain in the epigastrium, dull food intake, clear water and dark stool for several years. Nausea, vomiting, weakness of lower limbs, stirring to move qi and lassitude. After gastroscopy in hospitals, the patients diagnosed as 'stomach cancer' are not suitable for operation because of weak body.

After the patient takes the medicine, the patient has advanced diet, has strong spirit, no hiccup sound, red complexion, thick white fur and forceful pulse. The patient does not want to perform the operation again, requires to continue taking the medicine of the invention, and after half a year, goes to the hospital for the second gastroscopy, and the focus disappears.

6. Liver cancer

Eight patients, women, 52 patients, yuxi patients and workers, wherein the patients are progressively aggravated due to liver pain, the liver ultrasonic examination of two hospitals shows that the patients are typical beam-shaped waves, the liver right lobe lump is 5.2 multiplied by 4.7 square centimeters, the left lobe lump is 2.7 multiplied by 3.6 square centimeters, the radioactive isotope liver scanning shows that the patients are space-occupying lesion, the gamma-glutamyl transpeptidase is determined to be 138U/L, the alpha fetuin test is positive, the right diaphragm is obviously raised through the X-ray examination, the activity is limited, the patients have limited protrusion, the patients are punctured after the puncture, and the cytological examination and diagnosis are primary liver cancer.

After the medicine is taken for 2 months, the low fever is eliminated, the ascites is subsided, the abdominal circumference is 72 cm, and the fullness and distension are relieved. Appetite increase, yellow stain in skin and sclera subsides, liver retraction to 1 cm below costal area, no obvious pain in liver area, mild stool, pale, white, yellowish red tongue coating, hidden purple plaque, slow and wiry pulse. After the B-ultrasonic double-examination, the area of the liver right lobe tumor is 3.9 multiplied by 3.5 square centimeters, the area of the left lobe tumor is 2.6 multiplied by 2.7 square centimeters, the reduction of the area of the liver right lobe tumor is prompted to be 44.15 percent, the area of the left lobe tumor is reduced by 27.78 percent, the measurement of gamma-glutamyl transpeptidase is 26 units, alpha fetuin is negative, the right diaphragm is not obviously lifted by X-ray examination, and the patient continues to take the medicine for 6 months, so that the body is completely recovered and returns to work again.

Nine patients, male, 42 years old, cadre and red river, all find the hepatic parenchyma space occupying lesion and have positive alpha fetuin because the patients have a diagnosis in hospitals for epigastric distending pain, reduced appetite and dyspepsia respectively. And the patient goes to the outpatient examination of a tumor hospital, and confirms that the liver is affected by the space occupying property and the fetal globulin is positive again through isotope liver scanning and B ultrasonic examination. The primary liver cancer is confirmed. The traditional Chinese medicine is used for seeking diagnosis without operation indication. Admission checking: the liver is not under the right costal region, and the lung and liver are located between the fifth costal region of the right supraclavicular line without jaundice and ascites. And (3) CT examination: the liver right lobe can see a 4.4 multiplied by 2.5 density increasing area, the liver volume is increased, the quantity of alpha fetuin is 920 mu g/L, and the clinical diagnosis is primary liver cancer of stage II.

After the patient takes the medicine for 60 days, the distending pain of the liver area is improved and the appetite is increased, the tumor mass is reduced to 3.0 multiplied by 2.0 by B ultrasonic examination, and the quantity of alpha fetuin is reduced to 200 mug/L. After 1 year, the B-ultrasonic examination shows that the liver lesion disappears and alpha fetuin turns negative. CT scanning: the liver area has uniform density and normal volume. The clinical symptoms of the patient basically disappear, and the traditional Chinese medicine treatment in the outpatient clinic is continued after the patient is discharged. After more than 3 years, the B ultrasonic is periodically reviewed, and the liver still has no space occupying lesion.

7. Pancreatic cancer

Patients of ten years old, 38 years old and Pu' er tea feel abdominal distension and anorexia in the early years, and find that the upper abdomen has a lump, the upper abdomen has a half-month long time, nausea and vomiting, the whole body and the face are yellow, and paroxysmal severe pain in the upper abdomen. The patient goes to the hospital for examination: 12U for liver function turbidity and 7U for musk deer. Ultrasonic inspection: the liver swollen 2.5 cm and the spleen normal. In the first treatment of acute icteric hepatitis, analgesics such as dolantin are injected whenever pain occurs, but the condition is not improved but aggravated. Further examination was performed thereafter: x-ray barium meal examination shows that the duodenum is widened, and cancer cells are found by duodenum drainage smear examination. The diagnosis is as follows: pancreatic cancer. The operation treatment is introduced by other people to treat the disease by using traditional Chinese medicine because the patient does not want to operate.

After the medicine is taken for 30 days (one treatment course), the symptoms are relieved, the lumps are reduced earlier, the pain is slightly restrained, the injection of the analgesic is not needed, the medicine is used for the first time, and the excrement is cleared 1 time a day. The tongue is red and the coating is yellowish, the medicine of the invention is taken for 2 months, the condition is stable, the lumps disappear, the jaundice can be partially removed, and the pain is no longer existed. The patient goes to the hospital for examination: normal liver function, X-ray barium meal examination: the duodenal intestinal tract is widened and disappeared. The abdominal mass was not seen at the time of confirmation. The disease does not recur for more than four years, and the patient can be returned to normal work in the next year.

8. Carcinoma of large intestine

Eleven patients, women, 47 years old, yuxi, and patients with intestinal cancer (lump type) for more than 1 year, poor appetite, yellow and swollen face, abdominal pain and tenderness in the left lower, and can touch the lumps with egg size, tenesmus, dry and thin stool, purulent blood, malaise whole body, hypodynamia, shortness of breath, emaciation, thin and yellow greasy tongue coating, and wiry, slippery, thready and thready pulse.

After the patient takes the medicine for two months, the disease condition is obviously improved, abdominal distension is gradually eliminated, abdominal pain is gradually reduced, the patient can increase the content of the medicine, the medicine is added and reduced according to the upper part for treatment for 3 months, all symptoms are eliminated, the lumps disappear, the face is ruddy, the weight is increased by 10 jin compared with the weight before the medicine is taken, abnormal pathological phenomena do not occur in a lung chest piece and B ultrasonic examination, the systemic superficial lymph nodes are not transferred, biochemical examination, ESR, CEA and the like are in a normal range, and the patient can participate in light labor and restore work.

9. Cervical cancer

Twelve patients, women, 55 years old, confirmed in hospital as "cervical cancer stage III". The focus of infection after treatment can not be completely eliminated after three courses of radiotherapy in the hospital in the same year. The patients have weak constitution, short breath, hypodynamia, lusterless complexion, lumbago, leg weakness, difficulty in walking, and leukorrhagia with pus and blood odor. Pale tongue with white coating, thready and weak pulse, blood test: 2X 10/L of white blood cells, and the like, and is used for radiotherapy and liquid consumption.

After a patient takes the medicine for 3 months, the physical strength is gradually enhanced, all symptoms are improved, the leucorrhea is reduced, the patient takes the medicine continuously for three years, the focus is eliminated after the medicine is reviewed in a hospital, and other abnormalities are not found.

10. Ovarian cancer

Thirteen patients, women and 58 years old are in diffuse transition, the patients feel self-induced small abdominal pain, the patients visit the hospital in month 2, touch small abdominal masses in month 3, the B-ultrasonic examination shows that the abdominal masses are uncertain in nature, the patients go to the hospital for bilateral adnexectomy, and the pathological diagnosis after the operation is the III stage of double-ovary endometrioid carcinoma.

After the medicine is taken for half a year, the symptoms of a patient are obviously improved, the diet is increased, the lower abdominal pain is relieved, the symptoms of palpitation and short breath, dizziness and spontaneous perspiration and the like disappear, and the weight is increased by more than 20 kilograms. The patient can go to a certain hospital for a plurality of times to review, the tumor relapse is not found, and no cancer cell is found when the patient is taken as a cervical cancer prevention smear in the hospital.

The above description is only for the purpose of illustrating the preferred embodiments of the present invention and is not to be construed as limiting the invention, and any modifications, equivalents and improvements made within the spirit and principle of the present invention are intended to be included within the scope of the present invention.

Claims (8)

1. The application of an anticancer composition in preparing a medicament for treating cancer is characterized in that: the anti-cancer composition comprises the following components in parts by weight: 10 to 20 portions of pseudo-ginseng, 20 to 60 portions of dandelion, 5 to 15 portions of Yunnan manyleaf paris rhizome, 5 to 15 portions of ginseng, 5 to 15 portions of astragalus and 10 to 20 portions of ganoderma lucidum spore.

2. Use according to claim 1, characterized in that: the paint comprises the following components in parts by weight: 12 to 18 parts of pseudo-ginseng, 30 to 50 parts of dandelion, 7 to 12 parts of Yunnan manyleaf paris rhizome, 7 to 13 parts of ginseng, 7 to 13 parts of astragalus and 12 to 18 parts of ganoderma lucidum spore.

3. Use according to claim 1, characterized in that: the paint comprises the following components in parts by weight: 15 parts of pseudo-ginseng, 40 parts of dandelion, 10 parts of paris polyphylla, 10 parts of ginseng, 10 parts of astragalus membranaceus and 15 parts of ganoderma lucidum spores.

4. Use according to any one of claims 1 to 3, characterized in that: the pseudo-ginseng is the cut part of the pseudo-ginseng; the dandelion is root of dandelion; the Ganoderma is Yunnan plateau Ganoderma.

5. Use according to claim 1, characterized in that:

the preparation steps of the anticancer composition are as follows:

s1: pulverizing Notoginseng radix, herba Taraxaci, rhizoma paridis Yunnanensis, ginseng radix and radix astragali to no less than 40 mesh, breaking cell wall of Ganoderma spore with ultrafine pulverizer, and pulverizing to no less than 1200 mesh;

s2: mixing powders of Notoginseng radix, herba Taraxaci, rhizoma paridis Yunnanensis, ginseng radix, radix astragali and Ganoderma spore at a certain proportion, and granulating in a swing granulator.

6. Use according to claim 5, characterized in that: the preparation method of the anticancer composition further comprises the following steps of S-1: air-drying Notoginseng radix, herba Taraxaci, rhizoma paridis Yunnanensis, ginseng radix, radix astragali and Ganoderma spore until the water content of Notoginseng radix, herba Taraxaci, rhizoma paridis Yunnanensis, ginseng radix, radix astragali and Ganoderma spore is 5-7%.

7. Use according to claim 5 or 6, characterized in that: the preparation method of the anticancer composition further comprises the following steps of S-2: selecting pseudo-ginseng, dandelion, paris polyphylla, ginseng, astragalus and ganoderma lucidum spores, wherein the selection conditions are as follows: the content of total saponins of R1, rg1 and Rb1 in the pseudo-ginseng is more than or equal to 15.5 percent, the content of caffeic acid in dandelion is more than or equal to 0.020 percent, the total content of rhizoma paridis saponin I, rhizoma paridis saponin II, rhizoma paridis saponin III and rhizoma paridis saponin IV in Yunnan rhizoma paridis is more than or equal to 0.6 percent, the total content of ginsenoside Rg1 and ginsenoside Re in ginseng is more than or equal to 0.03 percent, the content of astragaloside in astragalus is more than or equal to 0.04 percent, the content of calycosin glucoside is more than or equal to 0.02 percent, and the content of ganoderma lucidum polysaccharide in ganoderma lucidum is more than or equal to 0.5 percent.

8. The use according to claim 1, characterized in that it comprises any one or more of the following (1) to (10):

(1) Preparing a medicament for treating breast cancer;

(2) Preparing a medicament for treating leukemia;

(3) Preparing a medicament for treating esophagus cancer;

(4) Preparing a medicament for treating lung cancer;

(5) Preparing a medicine for treating gastric cancer;

(6) Preparing a medicament for treating primary liver cancer;

(7) Preparing a medicament for treating pancreatic cancer;

(8) Preparing a medicament for treating colorectal cancer;

(9) Preparing a medicine for treating cervical cancer;

(10) Preparing the medicine for treating ovarian cancer.