CN102805844A - Medicine for treating liver cancer - Google Patents

Medicine for treating liver cancer Download PDF

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CN102805844A
CN102805844A CN2012103052206A CN201210305220A CN102805844A CN 102805844 A CN102805844 A CN 102805844A CN 2012103052206 A CN2012103052206 A CN 2012103052206A CN 201210305220 A CN201210305220 A CN 201210305220A CN 102805844 A CN102805844 A CN 102805844A
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CN102805844B (en
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王成德
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Abstract

The invention discloses a medicine for treating liver cancer. The medicine comprises the following Chinese herbal medicines of virgate wormwood herb, szechwan chinaberry fruit, cassia seed, tuber fleeceflower root, leech, ginseng, hawthorn fruit and the like in a weight ratio. According to the medicine, the effective rate of treating primary cancer liver in moderate and advanced stages is 76.2 percent, and tumors are stable and difficultly relapse after treatment. Experiments on hearts, livers, spleens, lungs and kidneys of animals are performed within the range of treatment dose, and the toxic or side effects are not obvious.

Description

A kind of medicine of treating hepatocarcinoma
Technical field
The present invention relates to tcm field, specifically, relate to a kind of medicine that can treat hepatocarcinoma and can suppress the HCC diffusion.
Background technology
Hepatocarcinoma is meant the malignant tumor that betides liver, comprises two kinds of primary hepatocarcinoma and secondary liver cancers, and mostly the hepatocarcinoma of the daily theory of people is primary hepatocarcinoma if referring to.Primary hepatocarcinoma is one of modal malignant tumor clinically, and according to recent statistics, the annual New Development liver cancer patient in the whole world is about 600,000, occupies the 5th of malignant tumor.Primary hepatocarcinoma can be divided into hepatocyte type hepatocarcinoma, bile duct cell type hepatocarcinoma and mixed carcinoma of liver by cell typing.Form by tumor can be divided into nodular type, massive type and diffuse type.Primary hepatocarcinoma belongs to high morbidity in China, and general male is more than the women.China is hepatitis B big country, the many development on the basis of hbv-liver cirrhosis of the hepatocarcinoma of China, and the hepatitis C patient also increasing gradually, also can develop into hepatocarcinoma after the hepatitis B.China's number of the infected accounts for the more than half of the whole world at present, accounts for 55% of global hepatocarcinoma patient, has become a big killer of serious threat China people health and lives, and its danger can not look down upon.
At present, the Therapeutic Method of hepatocarcinoma generally adopts excision, then the patient is carried out radiotherapy, chemotherapy; Because radiotherapy, the caused side effect of chemotherapy are bigger; So aspect liver cancer treatment, this method not only can not be effected a radical cure hepatocarcinoma; And also be a bigger injury, even accelerated patient's death to patient self.Certainly; In tcm field, occurred at present much about treating the Chinese medicine preparation of hepatocarcinoma; But these important prescriptions can not find the real root of hepatocarcinoma outbreak, and therapeutic effect is also pessimistic, after the patient takes; Obvious effective rate is low, cure rate is low, is a great problem of treating the Chinese medicine preparation of hepatocarcinoma at present.
Summary of the invention
The technical problem that the present invention will solve is to overcome above-mentioned defective, provides that a kind of obvious effective rate is high, therapeutic effect is good, the effective medicine of the treatment hepatocarcinoma that spreads of anticancer.
For addressing the above problem, the technical scheme that the present invention adopted is:
A kind of medicine of treating hepatocarcinoma is characterized in that, said medicine is made up of following raw materials according by weight:
5~15 parts of 5~20 parts of Radix Polygoni Multiflori of 5~20 parts of Semen Cassiaes of 20~30 parts of Fructus Toosendans of Herba Artemisiae Scopariae
10~30 portions of Saigae Tataricaes of Semen Sesami are pounced on 5~20 parts of 10~25 portions of Radix et Rhizoma Dysosmatiss of 10~20 parts of Herba Hedyotidis Diffusaes
15~20 parts of 10~20 portions of Herba Solani Nigris of 5~15 parts of Poria of 10~30 parts of Herba Agrimoniaes of Fructus Lycii
10~30 parts of 5~20 parts of Fructus Aurantiis of 15~20 portions of Radix Curcumaes of 10~20 parts of Spica Prunellaes of Rhizoma Corydalis
10~20 parts of 10~30 portions of Semen Plantaginiss of 5~15 portions of Radix Notoginsengs of 10~20 parts of Radix Stephaniae Sinicae (Radix Stephaniae Dielsianae) of Fructus Gardeniae
10~20 parts of 5~10 parts of Scolopendras of 10~30 parts of Flos Carthamis of 5~15 parts of Radix Angelicae Sinensis of Rhizoma Curcumae
10~30 parts of 10~50 parts of Radix Ginsengs of 1~5 portion of Fructus Crataegi of 15~20 parts of speckle chelas of Hirudo
10~20 parts in 5~15 portions of Radix Glycyrrhizaes of 10~30 parts of Cortex Magnoliae Officinalis of Radix Salviae Miltiorrhizae.
As a kind of improvement:
Said medicine is made up of following raw materials according by weight:
30 portions of antelopes of 10 portions of sesames of 15 parts of fleece-flowers root of 10 parts of cassia seeds of 25 parts of Fructus meliae toosendans of oriental wormwood are pounced on 20 parts in 10 portions of Radix Glycyrrhizaes of 15 parts of 20 parts of cortex magnoliae officinalis of 25 parts of reds sage root of 40 parts of gensengs of 3 portions of hawthorn of 15 parts of spot chelas of 10 portions of leech of 10 parts of centipedes of 25 parts of safflowers of 10 parts of Radix Angelicae Sinensis of 15 parts of curcuma zedoarys of 20 portions of plantain seeds of invaluable 10 portions of pseudo-ginsengs of 20 portions of cape jasmines of 15 parts of Fructus Aurantiis of 20 portions of root tubers of aromatic turmeric of 15 portions of selfheals of 15 parts of corydalis tubers of 15 portions of black nightshades of 10 parts of Poria cocos of 30 portions of hairyvein agrimonies of 15 portions of fruits of Chinese wolfberry of 25 portions of Dysosma versipellis of 15 parts of oldenlandia diffusas.
Herba Artemisiae Scopariae has protective effect to hepatic injury, and the ability transaminase lowering is active, alleviates swelling of liver cell, the change of balloon appearance, fat change and degree of necrosis.Capillarisin in the Herba Artemisiae Scopariae, 6, compositions such as 7-dimethoxy coumarin, arcapillin all have the function of detoxification of inducing liver drug enzyme, strengthening liver, complete, the hepatocellular regenerated hepatoprotective effect of promotion of protection liver plasma membrane.
Capillarisin and cirsimaritin have remarkable inhibition Hela cell and Ehrlich ascites cells proliferation function in the Herba Artemisiae Scopariae.In addition, the Herba Artemisiae Scopariae water decoction is to carcinogen---and AFB, mutagenic action (AFBI) has remarkable inhibition.The Herba Artemisiae Scopariae water decoction also has inhibitory action to the proliferative lesion and the sudden change of bone marrow micronucleus of sodium nitrite and the inductive SD Rat Esophagus of N-methylbenzylamine epithelium, and can reduce the expression of experimental esophageal tumor rat pathological tissues p53 and plain dependent kinase CDK2 of cycle.
So be function of gallbladder promoting with Herba Artemisiae Scopariae clearing away damp-heat, pharmacological action that jaundice eliminating subcutaneous ulcer effect is relevant, protect the liver, resisting pathogenic microbes, blood fat reducing, and effect such as analgesic, analgesia, antiinflammatory.
Fructus Toosendan is mainly gone into Liver Channel, the catharsis liver-heat, and promoting the circulation of QI to relieve pain have except that damp and hot, clearing away liver-fire, pain relieving, parasiticidal function.
Semen Cassiae has liver heat removing and eyesight improving, blood fat reducing, loosening bowel to relieve constipation, adjusting gastrointestinal expelling toxin, and the extract of Semen Cassiae also has protection and repair to acute liver damage.
Radix Polygoni Multiflori can reduce the deposition of liver inner cholesterol, reduces the low density lipoprotein, LDL in liver and the blood, and can play blood fat reducing, increases immunity, antidotal effect, is of value to the prevention and the treatment of fatty liver.
Semen Sesami is enriched blood and is made eye bright, the intestine moistening of dispeling the wind, the lactogenesis that promotes the production of body fluid, the liver benefiting hair care, keep fit body, the effect of defying age.In addition, contain a kind of composition of sesamin in the Semen Sesami, this composition can suppress growth, breeding and the diffusion of HCC effectively.
It is Cornu Saigae Tataricae that Saigae Tataricae pounces on, and has clearing away heat and alleviating pain, suppressing the hyperactive liver to relieve the wind syndrome, liver heat removing and eyesight improving, the blood antidotal effect of loosing.
Herba Hedyotidis Diffusae has heat-clearing and toxic substances removing, the eliminating carbuncle eliminating stagnation, and the effect of inducing diuresis to remove edema is used for laryngopharynx swelling and pain, dyspnea and cough due to lung-heat, the puckery pain of pyretic stranguria, jaundice due to damp-heat, venom, the skin ulcer hot carbuncle that swells is particularly treated jaundice, has remarkable efficacy.
Radix et Rhizoma Dysosmatis has dissipating phlegm and resolving masses; Stasis-dispelling and pain-killing; The effect of heat-clearing and toxic substances removing is used for cough; Laryngopharynx swelling and pain; Scrofula; Goiter; Carbuncle; Furuncle; Venom; Traumatic injury; Arthromyodynia.
Fructus Lycii can play nourishing the liver, tonifying liver, soothing the liver, the effect of transferring fat, blood pressure lowering, blood sugar lowering, anti-senility etc., and pharmacological evaluation shows that the Folium hydrangeae strigosae alkali that contains in the Fructus Lycii has the over-deposit that suppresses intrahepatic fat, promotes impaired hepatocellular regeneration and repair.
The effect that Herba Agrimoniae has hemostasis, is good for the stomach.
Poria ability enhancing human body immunity function, pachyman has tangible antitumor and protects the liver dirty effect.
Herba Solani Nigri has heat-clearing and toxic substances removing, the effect of promoting blood circulation and detumescence.
Rhizoma Corydalis has promoting blood circulation to remove blood stasis, promoting the circulation of QI analgesic function.
Spica Prunellae liver heat removing, eliminating stagnation, diuresis; Control diseases such as pestilence, acute mastitis, ophthalmalgia, jaundice, gonorrhea, hypertension, acute icteric infectious hepatitis.
Radix Curcumae has regulating qi to disperse stagnation, heart fire-clearing upset-relieving, the effect of promoting the function of the gallbladder to alleviate jaundice.
Fructus Aurantii has spleen benefiting and stimulating the appetite, transfers the five internal organs, the therapeutic method to keep the adverse QI flowing downwards, and preventing or arresting vomiting is contrary, the effect of expectorant.
Fructus Gardeniae has the effect of pathogenic fire purging relieving restlessness, clearing away heat-damp and promoting diuresis, removing pathogenic heat from blood and toxic substance from the body, cures mainly that calentura is vexed, liver-fire conjunctival congestion, headache, jaundice due to damp-heat.
Radix Stephaniae Sinicae (Radix Stephaniae Dielsianae) another name Radix Cissi Kerrii, stone qin potato, Stephania cepharatha Hayata have the effect of heat-clearing and toxic substances removing, benefiting stomach and stopping pain, dissipating blood stasis for subsidence of swelling.
Radix Notoginseng has the hemostasis of curing mainly, the effect of loose blood, analgesic therapy.
Semen Plantaginis has clearing away heat and promoting diuresis, eliminating dampness by diuresis antidiarrheal, makes eye bright, the expectorant effect.
Rhizoma Curcumae has removing blood stasis circulation of qi promoting, pain relieving, removing blood stasis, circulation of qi promoting removing food stagnancy analgesic effect.
Radix Angelicae Sinensis have enrich blood invigorate blood circulation, the effect of menstruction regulating and pain relieving, loosening bowel to relieve constipation, can regulate body's immunity, have antitumaous effect.
Flos Carthami has the effect of the latus rectum of invigorating blood circulation, eliminating stasis to stop pain.
Scolopendra has endogenous wind stopping spasmolytic, merit poison eliminating stagnation, removing obstruction in the collateral to relieve pain, it is anticancer to relieve internal heat, move back the effect that inflammation is controlled skin ulcer.
Contain hirudin in the Hirudo, hirudin has inhibitory action to tumor cell, and growth has certain inhibitory action to rat liver cancer.Because Hirudo has high anticoagulation, thereby help anticarcinogen and immunologically competent cell and immerse cancerous tissue and kill and wound cancerous cell.
Speckle chela removing blood stasis Xiao wei, merit poison phagedenoma is drawn red foaming, and cantharidin can make lame tissue be fragment and rotten to the corn shape to murine sarcoma-180 inhibitory action slightly.Be used to treat hepatocarcinoma clinically more.
Contain a kind of lipolytic enzyme in the Fructus Crataegi, help the digestion and the catabolism of fat food, thus the effect of triglyceride reducing; Often take all right coronary blood flow increasing, thereby reduce the cholesterol in the serum, prevent that fat from precipitating in liver, and then the infringement hepatocyte.
Radix Ginseng can increase the enzymatic activity of each material of liver metabolism; The detoxification ability of liver is strengthened, thus enhancing body to the tolerance of various chemical substances, experiment shows: Radix Ginseng can increase the activity of ethanol dehydrogenase in the liver; Can strengthen the function of detoxification of liver, the effect of anti-liver injury is also arranged; The Herba Herminii saponin has the effect of alleviating to the hepatic injury transaminase mass formed by blood stasis that carbon tetrachloride causes.
Radix Salviae Miltiorrhizae has the effect of promoting blood flow to regulate menstruation, stasis-dispelling and pain-killing, removing heat from blood eliminating carbuncle, the relieving restlessness that clears away heart-fire, nourishing blood to tranquillize the mind.
Cortex Magnoliae Officinalis has the circulation of qi promoting removing food stagnancy, dampness is removed effect full, lowering the adverse QI to relieve asthma.
Radix Glycyrrhizae has antiinflammatory, antiviral and effects such as protecting liver and detoxication and raise immunity, also has functions such as anti-cancer and cancer-preventing, interferon inducer and cell immunomodulator.
In sum, in above-mentioned Chinese medicine, Herba Artemisiae Scopariae, Herba Hedyotidis Diffusae, Spica Prunellae, Radix Curcumae and Fructus Gardeniae have the liver heat removing function of gallbladder promoting, particularly the liver cancer patient with jaundice are had remarkable efficacy; Herba Artemisiae Scopariae, Fructus Toosendan, Semen Cassiae, what is first, Semen Sesami blackly has detoxifcation, clearing away liver-fire, increase immunity, the function of defying age, reparation liver; Radix Stephaniae Sinicae (Radix Stephaniae Dielsianae), Radix Notoginseng, Semen Plantaginis, Rhizoma Curcumae have the effect of anti-inflammatory analgetic; Flos Carthami, Scolopendra, Hirudo, speckle chela have blood circulation promoting and blood stasis dispelling, anticancer effect relieves internal heat; Herba Agrimoniae and Fructus Aurantii can be regulated the intestines and stomach; Radix Ginseng, Radix Salviae Miltiorrhizae, Fructus Lycii, Radix Angelicae Sinensis have protect the liver, the effect of hepatoprotective, nourishing the liver; Other Chinese medicine ingredients is also brought into play corresponding separately effect respectively.
Effective combination that its effective ingredient is an amount of and just right, decocte with water be about one hour, and the elimination medicinal residues are just drinkable, at this moment; Complement each other between each medicine, learn from other's strong points to offset one's weaknesses, strengthening the spleen and stomach, benefiting vital QI and blood, strengthening the body resistance; The adjustment human body yin-yang balancing, and can kill cancerous cell effectively, get rid of carcinomycin, blood circulation promoting and blood stasis dispelling, hard masses softening and resolving; Tumour eliminating and analgesic is eliminated ascites, improves patient's immunity and anti-cancer ability, has no side effect, and reaches the therapeutic effect of treating both the principal and secondary aspects of a disease.
Medicine according to the invention reaches 76.2% for the advanced primary liver cancer effective percentage, and it is stable to control the posterior tuberosity body, is difficult for recurrence.And in the therapeutic dose scope, the animal heart, liver, spleen, lung, kidney are experimentized, do not see obvious toxicity.
Effect experiment
1, the standard of case selection:
Select cancer patient and liver cirrhosis patient that clinical manifestation is divided into five types totally 100 people at random, minimum 35 years old of age wherein, maximum 75 years old, 55 years old mean age; Tumor body maximum gauge 12cm, minimum 4cm, average 8cm; The course of disease is the shortest 10 months, and is the longest 4 years, and average course of disease is the hepatocarcinoma middle and advanced stage.Wherein 42 people treat history again.
2, the diagnostic criteria of disease:
Mainly show as hepatalgia, weak, become thin, the common sympton of abdominal distention, heating, jaundice.
3, administrated method:
Oral, once a day, one month is a course of treatment.
4, the criterion of curative effect:
Cure: the positive sign of symptom and objective determination disappears, and observes year no recidivist half a year to one continuously;
Produce effects: the tumor body obviously dwindles, and other symptom obviously disappears, and life prolongs;
Effectively: symptom makes moderate progress, and the tumor body dwindles about half, and other objective determination takes an evident turn for the better;
Invalid: symptom and objective determination do not have improvement, or only have short-term to improve, and deterioration person rapidly.
5, the clinical manifestation of liver cancer patient is divided into five types:
1. obvious tumorous type; 2. acute abdomen type; 3. invisible; 4. fever type; 5. transfevent.
6, efficacy result analysis:
Show a pair of 100 example ages and treat, be generally 2-5 the course of treatment, the survey report that the regular hospital of state of an illness diagnosis employing provides at the hepatocarcinoma and the liver cirrhosis patient in 35-75 year.
Table one
Type Case load Cure Produce effects Effectively Invalid Effective percentage
Obvious tumorous type 20 5 7 3 5 75.0%
The acute abdomen type 17 8 3 3 3 83.3%
Conceal type 13 2 3 4 4 69.0%
Fever type 21 8 6 2 5 76.0%
Transfevent 10 3 2 2 3 70.0%
Liver cirrhosis 19 12 4 3 0 84.0%
Comprehensive Assessment 100 38 25 17 20 76.2%
Can find out that from last table cure 38 examples, effective percentage reaches 76.2%, and through clinical proof, medicine of the present invention can obviously strengthen patient's body constitution, appetite obviously strengthens, the enhances human body immunologic function, and side effect is very little.
Below in conjunction with the specific embodiment the present invention is further specified.
The specific embodiment
Embodiment 1: a kind of medicine of treating hepatocarcinoma; Choose 25 parts of Herba Artemisiae Scopariaes, 10 parts of Fructus Toosendans, 15 parts of Semen Cassiaes, 10 parts of Radix Polygoni Multiflori, 30 parts of Semen Sesamis, Saigae Tataricae and pounce on 15 parts, 25 parts of Serpentis SHECAO, 15 parts of Radix et Rhizoma Dysosmatiss, 30 parts of Fructus Lycii, 10 parts of Herba Agrimoniaes, 15 parts in Poria, 15 parts of Herba Solani Nigris, 15 parts of Rhizoma Corydalis, 20 parts of Spica Prunellaes, 15 parts of Radix Curcumaes, 20 parts of Fructus Aurantiis, 15 parts of Fructus Gardeniaes, 10 parts of Radix Stephaniae Sinicae (Radix Stephaniae Dielsianae), 20 parts in Radix Notoginseng, 15 parts of Semen Plantaginiss, 10 parts of Rhizoma Curcumae, 25 parts of Radix Angelicae Sinensis, 10 parts on Flos Carthami, 10 parts of Scolopendras, 15 parts of Hirudos, 3 parts of speckle chelas, 40 parts of Fructus Crataegis, 25 parts of Radix Ginsengs, 20 parts of Radix Salviae Miltiorrhizaes, 10 parts of Cortex Magnoliae Officinalis, 20 parts of mixing of Radix Glycyrrhizae, wherein every part weight is greatly about about 0.5 gram.Earlier with Scolopendra, Hirudo, speckle chela pulverization, soaked 15-30 minute in 1: 5 ratio before mixing, slow fire heated 1-2 hour then, and the elimination medicinal residues are taken and got final product.Once-a-day, one after each meal, one month is a course of treatment.
Embodiment 2: a kind of medicine of treating hepatocarcinoma; Choose 20 parts of Herba Artemisiae Scopariaes, 20 parts of Fructus Toosendans, 5 parts of Semen Cassiaes, 15 parts of Radix Polygoni Multiflori, 30 parts of Semen Sesamis, Saigae Tataricae and pounce on 10 parts, 15 parts of Serpentis SHECAO, 10 parts of Radix et Rhizoma Dysosmatiss, 20 parts of Fructus Lycii, 15 parts of Herba Agrimoniaes, 10 parts in Poria, 20 parts of Herba Solani Nigris, 20 parts of Rhizoma Corydalis, 15 parts of Spica Prunellaes, 10 parts of Radix Curcumaes, 30 parts of Fructus Aurantiis, 10 parts of Fructus Gardeniaes, 15 parts of Radix Stephaniae Sinicae (Radix Stephaniae Dielsianae), 30 parts in Radix Notoginseng, 10 parts of Semen Plantaginiss, 15 parts of Rhizoma Curcumae, 30 parts of Radix Angelicae Sinensis, 5 parts on Flos Carthami, 15 parts of Scolopendras, 20 parts of Hirudos, 5 parts of speckle chelas, 50 parts of Fructus Crataegis, 30 parts of Radix Ginsengs, 10 parts of Radix Salviae Miltiorrhizaes, 15 parts of Cortex Magnoliae Officinalis, 15 parts of mixing of Radix Glycyrrhizae, wherein every part weight is greatly about about 0.5 gram.Earlier with Scolopendra, Hirudo, speckle chela pulverization, soaked 15-30 minute in 1: 5 ratio before mixing, slow fire heated 1-2 hour then, and the elimination medicinal residues are taken and got final product.Once-a-day, one after each meal, one month is a course of treatment.
Embodiment 3: a kind of medicine of treating hepatocarcinoma; Choose 30 parts of Herba Artemisiae Scopariaes, 5 parts of Fructus Toosendans, 20 parts of Semen Cassiaes, 5 parts of Radix Polygoni Multiflori, 10 parts of Semen Sesamis, Saigae Tataricae and pounce on 20 parts, 10 parts of Serpentis SHECAO, 20 parts of Radix et Rhizoma Dysosmatiss, 10 parts of Fructus Lycii, 5 parts of Herba Agrimoniaes, 20 parts in Poria, 20 parts of Herba Solani Nigris, 10 parts of Rhizoma Corydalis, 20 parts of Spica Prunellaes, 5 parts of Radix Curcumaes, 10 parts of Fructus Aurantiis, 20 parts of Fructus Gardeniaes, 5 parts of Radix Stephaniae Sinicae (Radix Stephaniae Dielsianae), 10 parts in Radix Notoginseng, 20 parts of Semen Plantaginiss, 5 parts of Rhizoma Curcumae, 10 parts of Radix Angelicae Sinensis, 10 parts on Flos Carthami, 12 parts of Scolopendras, 18 parts of Hirudos, 1 part of speckle chela, 10 parts of Fructus Crataegis, 10 parts of Radix Ginsengs, 30 parts of Radix Salviae Miltiorrhizaes, 5 parts of Cortex Magnoliae Officinalis, 10 parts of mixing of Radix Glycyrrhizae, wherein every part weight is greatly about about 0.5 gram.Earlier with Scolopendra, Hirudo, speckle chela pulverization, soaked 15-30 minute in 1: 5 ratio before mixing, slow fire heated 1-2 hour then, and the elimination medicinal residues are taken and got final product.Once-a-day, one after each meal, one month is a course of treatment.
Below be the part model case:
Case 1, summer, man, 60 years old; Qingzhou City Wang Fen town peasant, when Physical Examination, finding liver has tumor, the about 2-4 centimetre of radius; And with weak, become thin, symptom such as abdominal distention, be diagnosed as the primary hepatocarcinoma middle and late stage through hospital expert, patient and family members thereof select expectant treatment; Begin to take medicine of the present invention in December, 2009, take and go to hospital to do B ultrasonic after one month again, tumor obviously reduces; Drug withdrawal after taking medicine continuously three months goes examination in hospital to find that tumor disappears, and this patient's life so far.
Case 2, Wang, woman, 55 years old; The worker of Qingzhou City brewery causes the serious fibrosis of liver because of suffering from fatty liver for a long time, and with weak, become thin, symptom such as abdominal distention; The patient begins to take medicine of the present invention in January, 2010, take one month after, find that through the hospital ultrasound diagnosis liver takes a turn for the better to some extent; After taking three months continuously, through hospital's ultrasound diagnosis, it is normal that liver recovers basically.
Case 3, Hu, the woman, 65 years old, retired employees of Qingzhou City textile mills, the patient found in June, 2010 suffers from primary hepatocarcinoma, abdominal distension, hepatalgia, and ascites with jaundice symptom, are diagnosed as the hepatocarcinoma later stage through hospital, and the patient requires expectant treatment.Begin to take medicine of the present invention in July, 2010, postabdomen began to dwindle in one month, and liver refers to examine deliquescing, and after three months, lump reduces greatly, and ascites disappears basically.After take medicine of the present invention intermittently always, dead in May, 2012, from finding the hepatocarcinoma later stage, adhered to 2 years to dead.
Case 4, bavin, the man, 71 years old, Qingzhou City Zheng Mu town peasant, patient found in January, 2010 suffered from hepatocarcinoma, about 3.5 centimeters of tumor radius, abdominal distension, and ascites are diagnosed as the hepatocarcinoma later stage through hospital, and the patient requires expectant treatment.Begin to take medicine of the present invention in January, 2010, postabdomen began to dwindle in one month, and liver refers to examine deliquescing, and after three months, lump reduces greatly, and ascites disappears basically, and after continuing to take one month, lump disappears, and this patient still survives in generation at present.
Case 5, leaf, man, 49 years old; Qingzhou City Tan Fang town peasant, patient found in March, 2011 suffers from hepatocarcinoma, about 2 centimeters of tumor radius; With weak, become thin, symptom such as abdominal distention, heating, jaundice, be diagnosed as primary hepatocarcinoma through hospital, the patient requires expectant treatment.Begin to take medicine of the present invention in April, 2011, liver referred to examine deliquescing after hospital's ultrasound diagnosis finds that tumor begins to dwindle in one month, and after three months, lump disappears, and this patient still survives in generation at present, and can carry out general physical work.

Claims (2)

1. a medicine of treating hepatocarcinoma is characterized in that, said medicine is made up of following raw materials according by weight:
5~15 parts of 5~20 parts of Radix Polygoni Multiflori of 5~20 parts of Semen Cassiaes of 20~30 parts of Fructus Toosendans of Herba Artemisiae Scopariae
10~30 portions of Saigae Tataricaes of Semen Sesami are pounced on 5~20 parts of 10~25 portions of Radix et Rhizoma Dysosmatiss of 10~20 parts of Herba Hedyotidis Diffusaes
15~20 parts of 10~20 portions of Herba Solani Nigris of 5~15 parts of Poria of 10~30 parts of Herba Agrimoniaes of Fructus Lycii
10~30 parts of 5~20 parts of Fructus Aurantiis of 15~20 portions of Radix Curcumaes of 10~20 parts of Spica Prunellaes of Rhizoma Corydalis
10~20 parts of 10~30 portions of Semen Plantaginiss of 5~15 portions of Radix Notoginsengs of 10~20 parts of Radix Stephaniae Sinicae (Radix Stephaniae Dielsianae) of Fructus Gardeniae
10~20 parts of 5~10 parts of Scolopendras of 10~30 parts of Flos Carthamis of 5~15 parts of Radix Angelicae Sinensis of Rhizoma Curcumae
10~30 parts of 10~50 parts of Radix Ginsengs of 1~5 portion of Fructus Crataegi of 15~20 parts of speckle chelas of Hirudo
10~20 parts in 5~15 portions of Radix Glycyrrhizaes of 10~30 parts of Cortex Magnoliae Officinalis of Radix Salviae Miltiorrhizae.
2. a kind of medicine of treating hepatocarcinoma according to claim 1 is characterized in that said medicine is made up of following raw materials according by weight:
30 portions of antelopes of 10 portions of sesames of 15 parts of fleece-flowers root of 10 parts of cassia seeds of 25 parts of Fructus meliae toosendans of oriental wormwood are pounced on 20 parts in 10 portions of Radix Glycyrrhizaes of 15 parts of 20 parts of cortex magnoliae officinalis of 25 parts of reds sage root of 40 parts of gensengs of 3 portions of hawthorn of 15 parts of spot chelas of 10 portions of leech of 10 parts of centipedes of 25 parts of safflowers of 10 parts of Radix Angelicae Sinensis of 15 parts of curcuma zedoarys of 15 portions of plantain seeds of 20 parts of corydalis tubers of invaluable 10 portions of pseudo-ginsengs of 20 portions of cape jasmines of 15 parts of Fructus Aurantiis of 20 portions of root tubers of aromatic turmeric of 15 portions of selfheals of 15 parts of corydalis tubers of 15 portions of black nightshades of 10 parts of Poria cocos of 30 portions of hairyvein agrimonies of 15 portions of fruits of Chinese wolfberry of 25 portions of Dysosma versipellis of 15 parts of oldenlandia diffusas.
CN201210305220.6A 2012-08-16 2012-08-16 Medicine for treating liver cancer Expired - Fee Related CN102805844B (en)

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105055665A (en) * 2015-08-28 2015-11-18 潍坊医学院附属医院 Anti-hepatoma traditional Chinese medicine preparation
CN106177660A (en) * 2016-07-27 2016-12-07 朱华亭 A kind of Chinese medicine preparation for treating hepatocarcinoma and preparation method
CN107970245A (en) * 2018-01-08 2018-05-01 陈世伟 Three kinds of root of Beijing euphorbia alkane type triterpenoids are used to prepare Gli gene inhibitors and prevent the biomedical uses of liver-cancer medicine
CN108273010A (en) * 2018-04-22 2018-07-13 杨燕梅 A kind of Chinese medicine preparation and preparation method thereof for treating liver cancer

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1223133A (en) * 1998-11-24 1999-07-21 雷玉宏 Medicine for curing hepatitis B
CN1404844A (en) * 2001-08-16 2003-03-26 黄幸海 Liver-tonifying stone-removing Chinese medicine
CN1422642A (en) * 2001-12-04 2003-06-11 何文法 Series Chinese medicinal composition for treating tumor
CN1435241A (en) * 2002-12-03 2003-08-13 林万杰 Single-ingredient Chinese medicine pill and tablet
CN101612360A (en) * 2009-07-17 2009-12-30 肖嘉惠 The medicine of treatment hepatitis, liver cirrhosis, hepatocarcinoma
CN101628046A (en) * 2009-05-13 2010-01-20 九芝堂股份有限公司 Medicine combination and application thereof in preparing preparations for treating chronic hepatitis B

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1223133A (en) * 1998-11-24 1999-07-21 雷玉宏 Medicine for curing hepatitis B
CN1404844A (en) * 2001-08-16 2003-03-26 黄幸海 Liver-tonifying stone-removing Chinese medicine
CN1422642A (en) * 2001-12-04 2003-06-11 何文法 Series Chinese medicinal composition for treating tumor
CN1435241A (en) * 2002-12-03 2003-08-13 林万杰 Single-ingredient Chinese medicine pill and tablet
CN101628046A (en) * 2009-05-13 2010-01-20 九芝堂股份有限公司 Medicine combination and application thereof in preparing preparations for treating chronic hepatitis B
CN101612360A (en) * 2009-07-17 2009-12-30 肖嘉惠 The medicine of treatment hepatitis, liver cirrhosis, hepatocarcinoma

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105055665A (en) * 2015-08-28 2015-11-18 潍坊医学院附属医院 Anti-hepatoma traditional Chinese medicine preparation
CN106177660A (en) * 2016-07-27 2016-12-07 朱华亭 A kind of Chinese medicine preparation for treating hepatocarcinoma and preparation method
CN107970245A (en) * 2018-01-08 2018-05-01 陈世伟 Three kinds of root of Beijing euphorbia alkane type triterpenoids are used to prepare Gli gene inhibitors and prevent the biomedical uses of liver-cancer medicine
CN108273010A (en) * 2018-04-22 2018-07-13 杨燕梅 A kind of Chinese medicine preparation and preparation method thereof for treating liver cancer

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