CN115463076A

CN115463076A - Sea buckthorn fruit oil composition for repairing skin barrier and preparation method thereof

Info

Publication number: CN115463076A
Application number: CN202211296878.5A
Authority: CN
Inventors: 刘尧阳; 吴天一; 陈靖淞; 刘晓彬
Original assignee: Zhongke Future Wuxi Biotechnology Research Institute Co ltd
Current assignee: Zhongke Future Wuxi Biotechnology Research Institute Co ltd
Priority date: 2022-10-21
Filing date: 2022-10-21
Publication date: 2022-12-13
Anticipated expiration: 2042-10-21
Also published as: CN115463076B

Abstract

The application provides a seabuckthorn fruit oil composition for repairing a skin barrier and a preparation method thereof, and relates to the technical field of skin care products. A sea buckthorn fruit oil composition for repairing skin barriers comprises the following raw materials in parts by weight: 2-5 parts of glycerin, 2-6 parts of sea buckthorn fruit oil, 2-5 parts of hydrolyzed sodium hyaluronate, 0.5-2 parts of lecithin, 1-5 parts of ethylene diamine tetraacetic acid disodium, 1-5 parts of butanediol, 0.5-3 parts of ceramide, 3-8 parts of collagen, 0.5-2 parts of trehalose, 0.5-2 parts of bradykinin, 0.2-1 part of inositol, 1-5 parts of gastrodia elata extract, 1-5 parts of ginseng extract and 60-75 parts of deionized water. The raw materials have synergistic effect, and the skin barrier repair effect is better and faster.

Description

Sea buckthorn fruit oil composition for repairing skin barrier and preparation method thereof

Technical Field

The application relates to the technical field of skin care products, in particular to a seabuckthorn fruit oil composition for repairing skin barriers and a preparation method thereof.

Background

The skin, as a surface of the human body which contacts with the outside, plays an important role in protecting and maintaining the normal circulatory metabolism and water balance in the body. Due to climate change, air pollution and complexity of types and components in cosmetics, the possibility of sensitive skin appearing and receiving stimulation is improved, and in addition, the perception rate and attention of sensitive skin are gradually increased due to improvement of awareness of people on skin health.

The skin barrier is a tissue organ with the largest area of the human body, and covers the surface of the body, and the structural basis of the skin barrier is mainly the stratum corneum, epidermal lipids, natural moisturizing factors and the like. The healthy skin barrier can resist external harmful substances, irritants and sunlight from invading skin, and has moisturizing and regulating effects. However, due to environmental, dietary and wrong skin care, the skin barrier is easily damaged, so that the self-defense ability of the skin is insufficient, the skin is sensitive, aged, dry and desquamated, and simultaneously, various allergens cross the skin defense line, and the incidence of eczema, atopic dermatitis, skin pruritus and the like is gradually increased.

In the prior art, the doctor generally has the following orders for the impaired skin barrier: 1. well sun-proof; 2. the cleaning force and the oil control performance are not paid excessive attention, and mild cleaning products are selected as much as possible; 3. during the period of repairing skin, excessive cleaning is not needed, water is supplemented and moisture is preserved, and then repairing cream is applied; 4. during the repair of damaged skin barriers, it is desirable to leave them unapplied, and if makeup is necessary, care must be taken to remove the makeup completely; 5. applying a facial mask rarely; 6. avoid staying up all night. That is, the patient can make a subtraction on the skin, and the recovery is performed by depending on the capability of the skin, but the defects are also obvious: has slow effect.

Disclosure of Invention

The present application aims to provide a seabuckthorn fruit oil composition for repairing skin barrier, which has the advantage of rapidly helping skin repair skin barrier.

Another object of the present application is to provide a method for preparing a seabuckthorn fruit oil composition for repairing skin barrier, which is simple and convenient.

The technical problem to be solved by the application is achieved by adopting the following technical scheme.

In one aspect, the present application provides a seabuckthorn fruit oil composition for repairing a skin barrier, which comprises the following raw materials in parts by weight: 2-5 parts of glycerin, 2-6 parts of sea buckthorn fruit oil, 2-5 parts of hydrolyzed sodium hyaluronate, 0.5-2 parts of lecithin, 1-5 parts of ethylene diamine tetraacetic acid disodium, 1-5 parts of butanediol, 0.5-3 parts of ceramide, 3-8 parts of collagen, 0.5-2 parts of trehalose, 0.5-2 parts of bradykinin, 0.2-1 part of inositol, 1-5 parts of gastrodia elata extract, 1-5 parts of ginseng extract and 60-75 parts of deionized water.

In another aspect, the present embodiments provide a method for preparing a seabuckthorn fruit oil composition for repairing a skin barrier, comprising the steps of:

mixing glycerol, fructus Hippophae oil and lecithin, and heating to 70-80 deg.C to obtain a first mixture;

heating water, hydrolyzed sodium hyaluronate, disodium ethylene diamine tetraacetate, butanediol, ceramide, collagen, trehalose and inositol to 85-90 ℃ to obtain a second mixture;

adding the first mixture into the second mixture, stirring for emulsification, cooling, adding bradykinin, rhizoma Gastrodiae extract and Ginseng radix extract, and stirring to obtain the fructus Hippophae oil composition for repairing skin barrier.

Compared with the prior art, the embodiment of the application has at least the following advantages or beneficial effects:

the present application proceeds from 3 aspects with synergistic repair of the skin barrier: 1. the sea buckthorn fruit oil is adopted to play a role in diminishing inflammation and calming, and the gastrodia elata extract plays a role in dredging the channels and collaterals and promoting circulation, so that damaged cells and precipitated pigments in the skin are discharged out of the body from a lymphatic system along with metabolism of the body; 2. the collagen is adopted, so that the regeneration capacity of collagen blasts can be stimulated to be enhanced, and the result of collagen fiber regeneration is finally achieved. The aging of all tissues on the face is closely related to the loss of collagen, the regeneration of collagen is stimulated to reset fat tissues, the elasticity of face supporting ligaments is recovered, fascia is tightened, the color and the elasticity of skin are recovered, and the like; 3. on the basis of solving the problem of skin permeability, the strong water molecule associating capacity of ceramide is utilized to form a net structure in a horny layer to maintain the moisture of the skin, and the water and oil balance of the skin is maintained by combining other moisturizing ingredients, so that the skin repair effect is quicker and better.

Detailed Description

In order to make the objects, technical solutions and advantages of the embodiments of the present application clearer, the technical solutions of the embodiments of the present application will be clearly and completely described below. The examples, in which specific conditions are not specified, were carried out according to conventional conditions or conditions recommended by the manufacturer. The reagents or instruments used are not indicated by the manufacturer, and are all conventional products available commercially.

It should be noted that the embodiments and features of the embodiments in the present application may be combined with each other without conflict. The present application will be described in detail below with reference to specific examples.

A sea buckthorn fruit oil composition for repairing skin barriers comprises the following raw materials in parts by weight: 2-5 parts of glycerin, 2-6 parts of sea buckthorn fruit oil, 2-5 parts of hydrolyzed sodium hyaluronate, 0.5-2 parts of lecithin, 1-5 parts of ethylene diamine tetraacetic acid disodium, 1-5 parts of butanediol, 0.5-3 parts of ceramide, 3-8 parts of collagen, 0.5-2 parts of trehalose, 0.5-2 parts of bradykinin, 0.2-1 part of inositol, 1-5 parts of gastrodia elata extract, 1-5 parts of ginseng extract and 60-75 parts of deionized water.

The application proceeds from 3 aspects with a synergistic repair of the skin barrier: 1. the sea buckthorn fruit oil is adopted to play a role in diminishing inflammation and calming, the gastrodia elata extract plays a role in dredging the channels and collaterals and promoting circulation, and damaged cells and precipitated pigments in the skin are discharged out of the body from a lymphatic system along with metabolism of the body; 2. the collagen is adopted, so that the regeneration capacity of collagen blasts can be stimulated to be enhanced, and the result of collagen fiber regeneration is finally achieved. All tissues on the face are quite relevant to collagen loss, collagen regeneration is stimulated to restore adipose tissues, the elasticity of face supporting ligaments is recovered, fascia is tightened, skin color and elasticity are recovered, and the like; 3. on the basis of solving the problem of skin permeability, the strong water molecule association capacity of ceramide is utilized, the network structure formed in the horny layer is used for maintaining the moisture of the skin, and the water-oil balance of the skin is maintained by combining other moisturizing components, so that the skin repair effect is quicker and better.

In some embodiments of the present application, the seabuckthorn fruit oil composition comprises the following raw materials in parts by weight: 3 parts of glycerin, 4 parts of seabuckthorn fruit oil, 3 parts of hydrolyzed sodium hyaluronate, 1 part of lecithin, 2 parts of ethylene diamine tetraacetic acid disodium, 2 parts of butanediol, 2 parts of ceramide, 5 parts of collagen, 1 part of trehalose, 1 part of bradykinin, 0.5 part of inositol, 4 parts of gastrodia elata extract, 4 parts of ginseng extract and 70 parts of deionized water.

In some embodiments of the present application, the above gastrodia elata extract and ginseng extract are prepared by the following steps:

drying and crushing rhizoma Gastrodiae or Ginseng radix, adding ethanol for extracting, and collecting ethanol extractive solution;

concentrating the ethanol extractive solution to obtain fluid extract, diluting, precipitating to remove impurities, eluting with deionized water and ethanol, collecting ethanol eluate, concentrating to obtain fluid extract, and drying.

In some embodiments of the present application, the drying temperature is 50 to 60 ℃, the crushed mixture is sieved through a 50 to 100-mesh sieve, the concentration of the ethanol is 90 to 95%, and the mass ratio of the gastrodia elata or the ginseng to the ethanol is 1: (5-10).

In some embodiments of the present application, the preparation method of the seabuckthorn fruit oil comprises: pulping fructus Hippophae, adding salt, stirring, centrifuging, extracting the upper layer juice, and collecting the extract.

In some embodiments of the present application, the mass ratio of the salt to the fructus hippophae is (1-3): 100, the centrifugation temperature is 40-50 ℃, the centrifugation speed is 7000-8000r/min, and the centrifugation time is 3-8min.

A method for preparing a seabuckthorn fruit oil composition for repairing skin barrier comprises the following steps:

In some embodiments of the present application, the temperature of the stirring emulsification is 60-70 ℃, the stirring speed is 2000-3000r/min, and the stirring time is 10-15min.

In some embodiments of the present application, the reduced temperature is 25-40 ℃.

The features and properties of the present application are described in further detail below with reference to examples.

Example 1

A fructus Hippophae oil composition for repairing skin barrier is prepared by:

1. preparing a gastrodia elata extract and a ginseng extract: drying Ginseng radix at 55 deg.C to constant temperature, taking out, crushing, and sieving with 60 mesh sieve to obtain Ginseng radix powder; mixing ginseng powder with ethanol with the concentration of 95% (ginseng: ethanol mass ratio is 1. The rhizoma Gastrodiae extract is prepared by the same extraction method.

2. Preparing sea buckthorn fruit oil: cleaning seabuckthorn fruits, adding 2 times of water, beating the cleaned seabuckthorn fruits into seabuckthorn fruit pulp by using a wall breaking machine, adding salt (the mass ratio of the seabuckthorn fruits to the salt is 100: 3) into the seabuckthorn fruit pulp, uniformly stirring, heating to 50 ℃, centrifuging at the temperature, wherein the centrifugation speed is 7500r/min, the centrifugation time is 5min, and extracting upper-layer fruit juice after centrifuging to obtain seabuckthorn fruit oil.

3. Preparing a sea buckthorn fruit oil composition: weighing 3g of glycerol, 4g of seabuckthorn fruit oil and 1g of lecithin, and mixing at 75 ℃ to obtain a first mixture; weighing 70g of water, 3g of hydrolyzed sodium hyaluronate, 2g of ethylene diamine tetraacetic acid disodium, 2g of butanediol, 2g of ceramide, 5g of collagen, 1g of trehalose and 0.5g of inositol, and uniformly mixing at 90 ℃ to obtain a second mixture; adding the first mixture into the second mixture, keeping the temperature at 65 ℃, stirring and emulsifying at the speed of 2500r/min for 10min, removing the heat source, continuously stirring, cooling to 35 ℃, adding 1g of bradykinin, 4g of gastrodia elata extract and 4g of ginseng extract, and stirring to obtain the seabuckthorn fruit oil composition for repairing skin barriers.

The main technical indexes of the seabuckthorn fruit oil composition for repairing skin barrier of the embodiment are as follows:

appearance: the paste is fine and uniform;

pH：5.0-7.0；

stability: the temperature of the thermostat is 45 ℃ and is unchanged for 3 months;

the total number of colonies is less than or equal to 10cfu/g;

the total number of the mould yeasts is less than or equal to 10cfu/g;

pathogenic bacteria: not detected;

and (3) irritation test: has no irritation.

Example 2

A fructus Hippophae oil composition for repairing skin barrier is prepared by:

1. preparing a gastrodia tuber extract and a ginseng extract: drying Ginseng radix at 60 deg.C to constant temperature, taking out, crushing, and sieving with 60 mesh sieve to obtain Ginseng radix powder; mixing Ginseng radix powder with 92% ethanol (Ginseng radix: ethanol mass ratio is 1. The rhizoma Gastrodiae extract is prepared by the same extraction method.

2. Preparing sea buckthorn fruit oil: cleaning the sea buckthorn fruits, adding 2 times of water, beating the cleaned sea buckthorn fruits into sea buckthorn fruit pulp by using a wall breaking machine, adding salt (the mass ratio of the sea buckthorn fruits to the salt is 100.

3. Preparing a sea buckthorn fruit oil composition: weighing 5g of glycerol, 4g of seabuckthorn fruit oil and 0.5g of lecithin, and mixing at 75 ℃ to obtain a first mixture; weighing 65g of water, 5g of hydrolyzed sodium hyaluronate, 1.5g of ethylene diamine tetraacetic acid disodium, 2g of butanediol, 1g of ceramide, 5g of collagen, 1g of trehalose and 1g of inositol, and uniformly mixing at 85 ℃ to obtain a second mixture; adding the first mixture into the second mixture, keeping the temperature at 60 ℃, stirring and emulsifying at the speed of 2500r/min for 10min, removing the heat source, continuously stirring, cooling to 32 ℃, adding 2g of bradykinin, 2g of gastrodia elata extract and 5g of ginseng extract, and stirring to obtain the seabuckthorn fruit oil composition for repairing skin barriers.

Example 3

A fructus Hippophae oil composition for repairing skin barrier is prepared by:

1. preparing a gastrodia elata extract and a ginseng extract: drying Ginseng radix at 50 deg.C to constant temperature, taking out, crushing, and sieving with 50 mesh sieve to obtain Ginseng radix powder; mixing Ginseng radix powder with 92% ethanol (Ginseng radix: ethanol mass ratio is 1. The rhizoma Gastrodiae extract is prepared by the same extraction method.

2. Preparing sea buckthorn fruit oil: cleaning seabuckthorn fruits, adding 2.5 times of water, beating the cleaned seabuckthorn fruits into seabuckthorn fruit pulp by using a wall breaking machine, adding salt (the mass ratio of the seabuckthorn fruits to the salt is 100: 2) into the seabuckthorn fruit pulp, uniformly stirring, heating to 45 ℃, centrifuging at the temperature, wherein the centrifugation speed is 8000r/min, the centrifugation time is 5min, and extracting upper-layer fruit juice after centrifuging to obtain seabuckthorn fruit oil.

3. Preparing the sea buckthorn fruit oil composition: weighing 2g of glycerol, 6g of seabuckthorn fruit oil and 1.2g of lecithin, and mixing at 75 ℃ to obtain a first mixture; weighing 75g of water, 2g of hydrolyzed sodium hyaluronate, 5g of ethylene diamine tetraacetic acid disodium, 1g of butanediol, 0.5g of ceramide, 5g of collagen, 2g of trehalose and 0.2g of inositol, and uniformly mixing at 85 ℃ to obtain a second mixture; adding the first mixture into the second mixture, keeping the temperature at 60 ℃, stirring and emulsifying at the speed of 2000r/min for 10min, removing the heat source, continuously stirring, cooling to 32 ℃, adding 1.5g of bradykinin, 5g of gastrodia elata extract and 2g of ginseng extract, and stirring to obtain the seabuckthorn fruit oil composition for repairing skin barriers.

Example 4

A fructus Hippophae oil composition for repairing skin barrier is prepared by:

1. preparing a gastrodia elata extract and a ginseng extract: drying Ginseng radix at 50 deg.C to constant temperature, taking out, crushing, and sieving with 100 mesh sieve to obtain Ginseng radix powder; mixing ginseng powder with 92% ethanol (the mass ratio of ginseng to ethanol is 1. The rhizoma Gastrodiae extract is prepared by the same extraction method.

2. Preparing sea buckthorn fruit oil: cleaning the sea buckthorn fruits, adding 2.5 times of water, beating the fruits into sea buckthorn fruit pulp by a wall breaking machine, adding salt (the mass ratio of the sea buckthorn fruits to the salt is 100: 1) into the sea buckthorn fruit pulp, stirring uniformly, heating to 45 ℃, centrifuging at the temperature, wherein the centrifugation speed is 8000r/min, the centrifugation time is 5min, and extracting upper-layer fruit juice after centrifuging to obtain the sea buckthorn fruit oil.

3. Preparing a sea buckthorn fruit oil composition: weighing 4g of glycerol, 3g of sea buckthorn fruit oil and 2g of lecithin, and mixing at 75 ℃ to obtain a first mixture; weighing 72g of water, 2.6g of hydrolyzed sodium hyaluronate, 5g of ethylene diamine tetraacetic acid disodium, 3g of butanediol, 0.5g of ceramide, 5g of collagen, 2g of trehalose and 0.8g of inositol, and uniformly mixing at 85 ℃ to obtain a second mixture; adding the first mixture into the second mixture, keeping the temperature at 60 ℃, stirring and emulsifying at the speed of 2000r/min for 10min, removing the heat source, continuously stirring, cooling to 32 ℃, adding 0.5g of bradykinin, 3g of gastrodia elata extract and 2g of ginseng extract, and stirring to obtain the seabuckthorn fruit oil composition for repairing skin barriers.

Example 5

A fructus Hippophae oil composition for repairing skin barrier is prepared by:

1. preparing a gastrodia elata extract and a ginseng extract: drying Ginseng radix at 50 deg.C to constant temperature, taking out, crushing, and sieving with 80 mesh sieve to obtain Ginseng radix powder; mixing ginseng powder with 90% ethanol (the mass ratio of ginseng to ethanol is 1. The rhizoma Gastrodiae extract is prepared by the same extraction method.

2. Preparing sea buckthorn fruit oil: cleaning seabuckthorn fruits, adding 2 times of water, beating the cleaned seabuckthorn fruits into seabuckthorn fruit pulp by using a wall breaking machine, adding salt (the mass ratio of the seabuckthorn fruits to the salt is 100: 1) into the seabuckthorn fruit pulp, uniformly stirring, heating to 45 ℃, centrifuging at the temperature, wherein the centrifugation speed is 8000r/min, the centrifugation time is 5min, and extracting upper-layer fruit juice after centrifuging to obtain seabuckthorn fruit oil.

3. Preparing the sea buckthorn fruit oil composition: weighing 4g of glycerol, 5g of sea buckthorn fruit oil and 0.5g of lecithin, and mixing at 75 ℃ to obtain a first mixture; weighing 65g of water, 2.6g of hydrolyzed sodium hyaluronate, 5g of ethylene diamine tetraacetic acid, 3g of butanediol, 0.8g of ceramide, 5g of collagen, 2g of trehalose and 0.8g of inositol, and uniformly mixing at 90 ℃ to obtain a second mixture; adding the first mixture into the second mixture, keeping the temperature at 70 ℃, stirring and emulsifying at the speed of 3000r/min for 10min, removing the heat source, continuously stirring, cooling to 32 ℃, adding 1g of bradykinin, 3g of gastrodia elata extract and 2g of ginseng extract, and stirring to obtain the seabuckthorn fruit oil composition for repairing skin barriers.

Comparative example 1

The comparative example differs from example 1 in that no seabuckthorn fruit oil is added in the comparative example.

Comparative example 2

This comparative example differs from example 1 in that no bradykinin is added.

Comparative example 3

This comparative example differs from example 1 in that no collagen was added.

Comparative example 4

This comparative example differs from example 1 in that no ceramide is added.

Examples of the experiments

The products prepared in the examples 1, 3 and comparative examples 1 to 4 of the present application were subjected to a long-term repair function test: volunteers 350 (age 21-52 years) were randomly divided into 7 groups, 50/group, and 7 experimental groups corresponding to example 1, example 3, comparative examples 1-4, and blank group, respectively.

Except for the blank group, each group was used with the product prepared from the corresponding group after morning and evening each day, and no other cosmetic was used during the experiment.

The moisture, fat and pH of the face of the subject were measured before and after the experiment, respectively, and the results are shown in table 1.

TABLE 1

After the experiment (15 days), the appearance of each volunteer, including pox, inflammation, etc., was evaluated and classified into three grades of effective, effective and ineffective according to the effect, and the results are shown in table 2.

The obvious effect is that the integral of symptoms and signs is reduced by more than or equal to 80 percent.

The effective rate is that the integral of symptoms and signs is reduced by more than or equal to 30 percent and less than 80 percent.

The symptoms and the physical signs are reduced by less than 30 percent.

TABLE 2

As can be seen from table 2, the products prepared in examples 1 and 3 of the present application have a very good effect on repairing the skin barrier, which is improved compared to you 1, comparative example 2 and comparative example 4, but the collagen is not added in comparative example 3, and the effect of some methods is even lower than that of the blank examples, which indicates that blindly using cosmetics without conditioning the skin permeability may adversely affect the skin.

Note: all subjects had no adverse effects after the experiment.

In summary, the seabuckthorn fruit oil composition for repairing skin barrier and the preparation method thereof according to the embodiments of the present application have the following advantages:

the application proceeds from 3 aspects with a synergistic repair of the skin barrier: 1. the sea buckthorn fruit oil is adopted to play a role in diminishing inflammation and calming, the gastrodia elata extract plays a role in dredging the channels and collaterals and promoting circulation, and damaged cells and precipitated pigments in the skin are discharged out of the body from a lymphatic system along with metabolism of the body; 2. the collagen is adopted, so that the regeneration capacity of collagen blasts can be stimulated to be enhanced, and the result of collagen fiber regeneration is finally achieved. All facial tissues are quite relevant to collagen loss, the collagen regeneration is stimulated to restore adipose tissues, the elasticity of facial supporting ligaments is recovered, fascia is tightened, the skin color and elasticity are recovered, and the like. 3. On the basis of solving the problem of skin permeability, the strong water molecule association capacity of ceramide is utilized, the network structure formed in the horny layer is used for maintaining the moisture of the skin, and the water-oil balance of the skin is maintained by combining other moisturizing components, so that the skin repair effect is quicker and better.

The embodiments described above are some, but not all embodiments of the present application. The detailed description of the embodiments of the present application is not intended to limit the scope of the claimed application, but is merely representative of selected embodiments of the application. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present application.

Claims

1. A sea buckthorn fruit oil composition for repairing skin barrier is characterized by comprising the following raw materials in parts by weight: 2-5 parts of glycerol, 2-6 parts of sea buckthorn fruit oil, 2-5 parts of hydrolyzed sodium hyaluronate, 0.5-2 parts of lecithin, 1-5 parts of ethylene diamine tetraacetic acid disodium, 1-5 parts of butanediol, 0.5-3 parts of ceramide, 3-8 parts of collagen, 0.5-2 parts of trehalose, 0.5-2 parts of bradykinin, 0.2-1 part of inositol, 1-5 parts of gastrodia elata extract, 1-5 parts of ginseng extract and 60-75 parts of deionized water.

2. The seabuckthorn fruit oil composition for repairing skin barriers according to claim 1, which comprises the following raw materials in parts by weight: 3 parts of glycerin, 4 parts of seabuckthorn fruit oil, 3 parts of hydrolyzed sodium hyaluronate, 1 part of lecithin, 2 parts of ethylene diamine tetraacetic acid disodium, 2 parts of butanediol, 2 parts of ceramide, 5 parts of collagen, 1 part of trehalose, 1 part of bradykinin, 0.5 part of inositol, 4 parts of gastrodia elata extract, 4 parts of ginseng extract and 70 parts of deionized water.

3. The seabuckthorn fruit oil composition for repairing skin barrier according to claim 1 or 2, wherein the preparation method of the gastrodia elata extract and the ginseng extract comprises the following steps:

4. The seabuckthorn fruit oil composition for repairing a skin barrier according to claim 3, wherein the drying temperature is 50-60 ℃, the seabuckthorn fruit oil composition is crushed and then sieved through a 50-100-mesh sieve, the concentration of the ethanol is 90-95%, and the mass ratio of the gastrodia elata or the ginseng to the ethanol is 1: (5-10).

5. The composition of claim 1 or 2, wherein the seabuckthorn fruit oil is prepared by the following steps: pulping fructus Hippophae, adding salt, stirring, centrifuging, extracting the upper layer juice, and collecting the extract.

6. The seabuckthorn fruit oil composition for repairing skin barriers according to claim 5, wherein the mass ratio of the salt to the seabuckthorn fruits is (1-3): 100, the centrifugation temperature is 40-50 ℃, the centrifugation speed is 7000-8000r/min, and the centrifugation time is 3-8min.

7. A method of preparing a seabuckthorn fruit oil composition for use in the repair of skin barriers according to any one of claims 1 to 6, comprising the steps of:

8. The method of claim 7, wherein the emulsification temperature is 60-70 ℃, the stirring rate is 2000-3000r/min, and the stirring time is 10-15min.

9. The method of claim 7, wherein the temperature of the composition is 25-40 ℃.