CN115463076B - Sea buckthorn fruit oil composition for repairing skin barrier and preparation method thereof - Google Patents
Sea buckthorn fruit oil composition for repairing skin barrier and preparation method thereof Download PDFInfo
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Abstract
The application provides a sea buckthorn fruit oil composition for repairing skin barriers and a preparation method thereof, and relates to the technical field of skin care products. The sea buckthorn fruit oil composition for repairing skin barrier comprises the following raw materials in parts by weight: 2-5 parts of glycerol, 2-6 parts of sea buckthorn fruit oil, 2-5 parts of hydrolyzed sodium hyaluronate, 0.5-2 parts of lecithin, 1-5 parts of disodium ethylenediamine tetraacetate, 1-5 parts of butanediol, 0.5-3 parts of ceramide, 3-8 parts of collagen, 0.5-2 parts of trehalose, 0.5-2 parts of bradykinin, 0.2-1 part of inositol, 1-5 parts of gastrodia elata extract, 1-5 parts of ginseng extract and 60-75 parts of deionized water. The raw materials of the application act synergistically to play a better and faster skin barrier repairing effect.
Description
Technical Field
The application relates to the technical field of skin care products, in particular to a sea buckthorn fruit oil composition for repairing skin barriers and a preparation method thereof.
Background
The skin is used as the contact surface between the human body and the outside, and plays an important role in protecting and maintaining the normal circulation metabolism of the human body and the water balance in the human body. Due to climate change, air pollution and complexity of types and components in cosmetics, the possibility of appearance and stimulation of sensitive skin is improved, and in addition, the awareness of people on skin health is improved, and the perception rate and the attention of the sensitive skin are gradually increased.
The skin barrier is that the skin is used as the tissue organ with the largest area of the human body and covers the surface of the body, and the structural basis of the skin barrier is mainly the stratum corneum, the epidermal lipid, the natural moisturizing factors and the like. The healthy skin barrier is capable of protecting the skin from external harmful substances, irritants and sunlight, and has moisturizing and conditioning effects. However, skin barriers are easily damaged due to environmental, dietary and wrong skin care, etc., so that the skin itself has insufficient defenses, leading to skin sensitivity, aging, dryness and desquamation, while various allergens cross the skin defense line, thereby leading to an increasing incidence of eczema, atopic dermatitis, skin pruritus, etc.
In the prior art, aiming at the damage of the skin barrier, doctors generally have the following requirements: 1. sun protection is well done; 2. the moderate cleaning products are selected as much as possible without excessively paying attention to cleaning strength and oil control; 3. during the period of repairing skin, excessive cleaning is not suitable, water supplementing and moisturizing are performed, and then repairing face cream is smeared; 4. during repair of damaged skin barrier, it is desirable to make up free, and if make up is necessary, care must be taken to remove the makeup thoroughly; 5. applying a mask less; 6. avoid staying up overnight. That is, the patient can make a subtraction on the skin and recover the skin by relying on the ability of the skin itself, but the defects are obvious: has slow effect.
Disclosure of Invention
The application aims to provide a sea buckthorn fruit oil composition for repairing skin barriers, which has the advantage of quickly helping skin repair skin barriers.
Another object of the present application is to provide a preparation method of a sea buckthorn fruit oil composition for repairing skin barrier, which is simple and convenient.
The application solves the technical problems by adopting the following technical scheme.
In one aspect, the embodiment of the application provides a seabuckthorn fruit oil composition for repairing skin barrier, which comprises the following raw materials in parts by weight: 2-5 parts of glycerol, 2-6 parts of sea buckthorn fruit oil, 2-5 parts of hydrolyzed sodium hyaluronate, 0.5-2 parts of lecithin, 1-5 parts of disodium ethylenediamine tetraacetate, 1-5 parts of butanediol, 0.5-3 parts of ceramide, 3-8 parts of collagen, 0.5-2 parts of trehalose, 0.5-2 parts of bradykinin, 0.2-1 part of inositol, 1-5 parts of gastrodia elata extract, 1-5 parts of ginseng extract and 60-75 parts of deionized water.
In another aspect, embodiments of the present application provide a method of preparing a seabuckthorn fruit oil composition for repairing skin barrier, comprising the steps of:
mixing glycerol, oleum Hippophae and lecithin, and heating to 70-80deg.C to obtain a first mixture;
heating water, hydrolyzed sodium hyaluronate, disodium ethylenediamine tetraacetate, butanediol, ceramide, collagen, trehalose and inositol to 85-90 ℃ to obtain a second mixture;
adding the first mixture into the second mixture, stirring for emulsification, cooling, adding bradykinin, rhizoma Gastrodiae extract and Ginseng radix extract, and stirring to obtain the fructus Hippophae oil composition for repairing skin barrier.
Compared with the prior art, the embodiment of the application has at least the following advantages or beneficial effects:
the application performs synergistic repair of the skin barrier from 3 aspects: 1. the sea buckthorn fruit oil is adopted to play a role in diminishing inflammation and calming, the gastrodia elata extract plays a role in dredging channels and collaterals and promoting circulation, and damaged cells and precipitated pigment in the skin are discharged out of the body along with metabolism of the body by a lymphatic system; 2. the application adopts collagen, can stimulate the regeneration capability of collagen parent cells to strengthen, and finally achieves the regeneration result of collagen fibers. The aging of all tissues of the face is closely related to the loss of collagen, the regeneration of the collagen is stimulated to restore the adipose tissues, the facial support ligament is elastically restored, the fascia is tightened, the skin color and the elasticity are restored, and the like, and the ginseng extract is matched, so that the collagen-based facial tissue has the effects of strengthening the cell activity and promoting the collagen activity, and the collagen-based facial tissue can promote the collagen growth, rebuild cells, improve the stratum corneum from inside and reduce the skin permeability as soon as possible; 3. on the basis of solving the skin permeability, the water content of the skin is maintained by utilizing the strong capability of the ceramide for associating water molecules and the network structure formed in the stratum corneum, and the water-oil balance of the skin is maintained by combining other moisturizing components, so that a faster and better skin repairing effect is achieved.
Detailed Description
In order to make the objects, technical solutions and advantages of the embodiments of the present application more clear, the technical solutions of the embodiments of the present application will be clearly and completely described below. The specific conditions are not noted in the examples and are carried out according to conventional conditions or conditions recommended by the manufacturer. The reagents or apparatus used were conventional products commercially available without the manufacturer's attention.
It should be noted that, without conflict, the embodiments of the present application and features of the embodiments may be combined with each other. The present application will be described in detail with reference to specific examples.
The sea buckthorn fruit oil composition for repairing skin barrier comprises the following raw materials in parts by weight: 2-5 parts of glycerol, 2-6 parts of sea buckthorn fruit oil, 2-5 parts of hydrolyzed sodium hyaluronate, 0.5-2 parts of lecithin, 1-5 parts of disodium ethylenediamine tetraacetate, 1-5 parts of butanediol, 0.5-3 parts of ceramide, 3-8 parts of collagen, 0.5-2 parts of trehalose, 0.5-2 parts of bradykinin, 0.2-1 part of inositol, 1-5 parts of gastrodia elata extract, 1-5 parts of ginseng extract and 60-75 parts of deionized water.
The application performs synergistic repair of the skin barrier from 3 aspects: 1. the sea buckthorn fruit oil is adopted to play a role in diminishing inflammation and calming, the gastrodia elata extract plays a role in dredging channels and collaterals and promoting circulation, and damaged cells and precipitated pigment in the skin are discharged out of the body along with metabolism of the body by a lymphatic system; 2. the application adopts collagen, can stimulate the regeneration capability of collagen parent cells to strengthen, and finally achieves the regeneration result of collagen fibers. The aging of all tissues of the face is closely related to the loss of collagen, the regeneration of the collagen is stimulated to restore the adipose tissues, the facial support ligament is elastically restored, the fascia is tightened, the skin color and the elasticity are restored, and the like, and the ginseng extract is matched, so that the collagen-based facial tissue has the effects of strengthening the cell activity and promoting the collagen activity, and the collagen-based facial tissue can promote the collagen growth, rebuild cells, improve the stratum corneum from inside and reduce the skin permeability as soon as possible; 3. on the basis of solving the skin permeability, the water content of the skin is maintained by utilizing the strong capability of the ceramide for associating water molecules and the network structure formed in the stratum corneum, and the water-oil balance of the skin is maintained by combining other moisturizing components, so that a faster and better skin repairing effect is achieved.
In some embodiments of the present application, the above-mentioned seabuckthorn fruit oil composition comprises the following raw materials in parts by weight: 3 parts of glycerin, 4 parts of sea buckthorn fruit oil, 3 parts of hydrolyzed sodium hyaluronate, 1 part of lecithin, 2 parts of disodium edentate, 2 parts of butanediol, 2 parts of ceramide, 5 parts of collagen, 1 part of trehalose, 1 part of bradykinin, 0.5 part of inositol, 4 parts of gastrodia elata extract, 4 parts of ginseng extract and 70 parts of deionized water.
In some embodiments of the present application, the preparation methods of the gastrodia elata extract and the ginseng extract are as follows:
drying and crushing rhizoma Gastrodiae or Ginseng radix, adding ethanol, extracting with ethanol, and collecting ethanol extractive solution;
concentrating the ethanol extract to obtain fluid extract, adding dilution, precipitating to remove impurities, sequentially eluting with deionized water and ethanol, collecting ethanol eluate, concentrating to obtain fluid extract, and drying.
In some embodiments of the present application, the drying temperature is 50-60 ℃, the crushed gastrodia elata or ginseng is sieved by a 50-100 mesh sieve, the concentration of the ethanol is 90-95%, and the mass ratio of the gastrodia elata or ginseng to the ethanol is 1: (5-10).
In some embodiments of the present application, the preparation method of the seabuckthorn fruit oil comprises: pulping fructus Hippophae, adding salt, stirring, centrifuging, and extracting upper layer juice.
In some embodiments of the present application, the mass ratio of the salt to the seabuckthorn fruit is (1-3): 100, wherein the centrifugation temperature is 40-50 ℃, the centrifugation speed is 7000-8000r/min, and the centrifugation time is 3-8min.
A method of preparing a seabuckthorn fruit oil composition for repairing skin barrier comprising the steps of:
mixing glycerol, oleum Hippophae and lecithin, and heating to 70-80deg.C to obtain a first mixture;
heating water, hydrolyzed sodium hyaluronate, disodium ethylenediamine tetraacetate, butanediol, ceramide, collagen, trehalose and inositol to 85-90 ℃ to obtain a second mixture;
adding the first mixture into the second mixture, stirring for emulsification, cooling, adding bradykinin, rhizoma Gastrodiae extract and Ginseng radix extract, and stirring to obtain the fructus Hippophae oil composition for repairing skin barrier.
In some embodiments of the present application, the temperature of the above stirring emulsification is 60-70 ℃, the stirring rate is 2000-3000r/min, and the stirring time is 10-15min.
In some embodiments of the application, the temperature after the temperature reduction is 25-40 ℃.
The features and capabilities of the present application are described in further detail below in connection with the examples.
Example 1
A fructus Hippophae oil composition for repairing skin barrier is prepared by the following steps:
1. preparing rhizoma Gastrodiae extract and Ginseng radix extract: drying Ginseng radix at 55deg.C to constant temperature, taking out, crushing, and sieving with 60 mesh sieve to obtain Ginseng radix powder; mixing Ginseng radix powder with 95% ethanol (Ginseng radix: ethanol mass ratio is 1:10), extracting with ethanol for 2 times, mixing extractive solutions, concentrating to obtain fluid extract, adding 5 times deionized water into the fluid extract, stirring, eluting with resin, eluting with deionized water, eluting with ethanol, collecting ethanol eluate, concentrating to obtain fluid extract, drying the fluid extract at 70deg.C, and pulverizing to obtain Ginseng radix extract. The gastrodia elata extract is prepared by adopting the same extraction method.
2. Preparing sea buckthorn fruit oil: cleaning fructus Hippophae, adding 2 times of water, breaking wall, adding salt (sea buckthorn fruit: salt mass ratio of 100:3), stirring, heating to 50deg.C, centrifuging at 7500r/min for 5min, and extracting upper fruit juice to obtain oleum Hippophae.
3. Preparation of a seabuckthorn fruit oil composition: weighing 3g of glycerol, 4g of sea buckthorn fruit oil and 1g of lecithin, and mixing at 75 ℃ to obtain a first mixture; weighing 70g of water, 3g of hydrolyzed sodium hyaluronate, 2g of disodium ethylenediamine tetraacetate, 2g of butanediol, 2g of ceramide, 5g of collagen, 1g of trehalose and 0.5g of inositol, and uniformly mixing at 90 ℃ to obtain a second mixture; adding the first mixture into the second mixture, preserving heat at 65 ℃, stirring and emulsifying at 2500r/min for 10min, removing the heat source, continuously stirring, cooling to 35 ℃, adding 1g of bradykinin, 4g of gastrodia elata extract and 4g of ginseng extract, and stirring to obtain the sea buckthorn fruit oil composition for repairing skin barrier.
The main technical indexes of the seabuckthorn fruit oil composition for repairing skin barrier in the embodiment are as follows:
appearance: the paste is fine, uniform and consistent;
pH：5.0-7.0；
stability: 45 ℃, the constant temperature box has no change for 3 months;
the total colony count is less than or equal to 10cfu/g;
the total number of the mold yeasts is less than or equal to 10cfu/g;
a pathogenic bacterium: undetected;
irritation test: no stimulation.
Example 2
A fructus Hippophae oil composition for repairing skin barrier is prepared by the following steps:
1. preparing rhizoma Gastrodiae extract and Ginseng radix extract: drying Ginseng radix at 60deg.C to constant temperature, taking out, crushing, and sieving with 60 mesh sieve to obtain Ginseng radix powder; mixing Ginseng radix powder with 92% ethanol (Ginseng radix: ethanol mass ratio is 1:8), extracting with ethanol for 2 times, mixing the extractive solutions, concentrating to obtain fluid extract, adding 5 times deionized water into the fluid extract, stirring, eluting with resin, eluting with deionized water, eluting with ethanol, collecting ethanol eluate, concentrating to obtain fluid extract, drying the fluid extract at 65deg.C, and pulverizing to obtain Ginseng radix extract. The gastrodia elata extract is prepared by adopting the same extraction method.
2. Preparing sea buckthorn fruit oil: cleaning fructus Hippophae, adding 2 times of water, breaking wall, adding salt (sea buckthorn fruit: salt mass ratio of 100:2), stirring, heating to 45deg.C, centrifuging at 7500r/min for 5min, and extracting upper fruit juice to obtain oleum Hippophae.
3. Preparation of a seabuckthorn fruit oil composition: weighing 5g of glycerol, 4g of sea buckthorn fruit oil and 0.5g of lecithin, and mixing at 75 ℃ to obtain a first mixture; weighing 65g of water, 5g of hydrolyzed sodium hyaluronate, 1.5g of disodium ethylenediamine tetraacetate, 2g of butanediol, 1g of ceramide, 5g of collagen, 1g of trehalose and 1g of inositol, and uniformly mixing at 85 ℃ to obtain a second mixture; adding the first mixture into the second mixture, preserving heat at 60 ℃, stirring and emulsifying at 2500r/min for 10min, removing the heat source, continuously stirring, cooling to 32 ℃, adding 2g of bradykinin, 2g of gastrodia elata extract and 5g of ginseng extract, and stirring to obtain the sea buckthorn fruit oil composition for repairing skin barrier.
Example 3
A fructus Hippophae oil composition for repairing skin barrier is prepared by the following steps:
1. preparing rhizoma Gastrodiae extract and Ginseng radix extract: drying Ginseng radix at 50deg.C to constant temperature, taking out, crushing, and sieving with 50 mesh sieve to obtain Ginseng radix powder; mixing Ginseng radix powder with 92% ethanol (Ginseng radix: ethanol mass ratio is 1:5), extracting with ethanol for 2 times, mixing the extractive solutions, concentrating to obtain fluid extract, adding 8 times deionized water into the fluid extract, stirring, eluting with resin, eluting with deionized water, eluting with ethanol, collecting ethanol eluate, concentrating to obtain fluid extract, drying the fluid extract at 75deg.C, and pulverizing to obtain Ginseng radix extract. The gastrodia elata extract is prepared by adopting the same extraction method.
2. Preparing sea buckthorn fruit oil: cleaning fructus Hippophae, adding 2.5 times of water, breaking wall, adding salt (fructus Hippophae: salt mass ratio of 100:2), stirring, heating to 45deg.C, centrifuging at 8000r/min for 5min, and extracting upper layer juice to obtain oleum Hippophae.
3. Preparation of a seabuckthorn fruit oil composition: weighing 2g of glycerol, 6g of sea buckthorn fruit oil and 1.2g of lecithin, and mixing at 75 ℃ to obtain a first mixture; weighing 75g of water, 2g of hydrolyzed sodium hyaluronate, 5g of disodium ethylenediamine tetraacetate, 1g of butanediol, 0.5g of ceramide, 5g of collagen, 2g of trehalose and 0.2g of inositol, and uniformly mixing at 85 ℃ to obtain a second mixture; adding the first mixture into the second mixture, preserving heat at 60 ℃, stirring and emulsifying at a speed of 2000r/min for 10min, removing a heat source, continuously stirring, cooling to 32 ℃, adding 1.5g of bradykinin, 5g of gastrodia elata extract and 2g of ginseng extract, and stirring to obtain the sea buckthorn fruit oil composition for repairing skin barrier.
Example 4
A fructus Hippophae oil composition for repairing skin barrier is prepared by the following steps:
1. preparing rhizoma Gastrodiae extract and Ginseng radix extract: drying Ginseng radix at 50deg.C to constant temperature, taking out, crushing, and sieving with 100 mesh sieve to obtain Ginseng radix powder; mixing Ginseng radix powder with 92% ethanol (Ginseng radix: ethanol mass ratio is 1:10), extracting with ethanol for 1 time, mixing extractive solutions, concentrating, adding 5 times deionized water into the concentrated solution, stirring, eluting with resin, eluting with deionized water, eluting with ethanol, collecting ethanol eluate, concentrating to obtain fluid extract, drying the fluid extract at 75deg.C, and pulverizing to obtain Ginseng radix extract. The gastrodia elata extract is prepared by adopting the same extraction method.
2. Preparing sea buckthorn fruit oil: cleaning fructus Hippophae, adding 2.5 times of water, breaking wall, adding salt (fructus Hippophae: salt mass ratio of 100:1), stirring, heating to 45deg.C, centrifuging at 8000r/min for 5min, and extracting upper layer juice to obtain oleum Hippophae.
3. Preparation of a seabuckthorn fruit oil composition: weighing 4g of glycerol, 3g of sea buckthorn fruit oil and 2g of lecithin, and mixing at 75 ℃ to obtain a first mixture; 72g of water, 2.6g of hydrolyzed sodium hyaluronate, 5g of disodium ethylenediamine tetraacetate, 3g of butanediol, 0.5g of ceramide, 5g of collagen, 2g of trehalose and 0.8g of inositol are weighed and uniformly mixed at 85 ℃ to obtain a second mixture; adding the first mixture into the second mixture, preserving heat at 60 ℃, stirring and emulsifying at a speed of 2000r/min for 10min, removing a heat source, continuously stirring, cooling to 32 ℃, adding 0.5g of bradykinin, 3g of gastrodia elata extract and 2g of ginseng extract, and stirring to obtain the sea buckthorn fruit oil composition for repairing skin barrier.
Example 5
A fructus Hippophae oil composition for repairing skin barrier is prepared by the following steps:
1. preparing rhizoma Gastrodiae extract and Ginseng radix extract: drying Ginseng radix at 50deg.C to constant temperature, taking out, crushing, and sieving with 80 mesh sieve to obtain Ginseng radix powder; mixing Ginseng radix powder with 90% ethanol (Ginseng radix: ethanol mass ratio is 1:6), extracting with ethanol for 1 time, mixing the extractive solutions, concentrating, adding 5 times deionized water into the concentrated solution, stirring, eluting with resin, eluting with deionized water, eluting with ethanol, collecting ethanol eluate, concentrating to obtain fluid extract, drying the fluid extract at 65deg.C, and pulverizing to obtain Ginseng radix extract. The gastrodia elata extract is prepared by adopting the same extraction method.
2. Preparing sea buckthorn fruit oil: cleaning fructus Hippophae, adding 2 times of water, breaking wall, adding salt (sea buckthorn fruit: salt mass ratio of 100:1), stirring, heating to 45deg.C, centrifuging at 8000r/min for 5min, and extracting upper layer juice to obtain oleum Hippophae.
3. Preparation of a seabuckthorn fruit oil composition: weighing 4g of glycerol, 5g of sea buckthorn fruit oil and 0.5g of lecithin, and mixing at 75 ℃ to obtain a first mixture; weighing 65g of water, 2.6g of hydrolyzed sodium hyaluronate, 5g of disodium ethylenediamine tetraacetate, 3g of butanediol, 0.8g of ceramide, 5g of collagen, 2g of trehalose and 0.8g of inositol, and uniformly mixing at 90 ℃ to obtain a second mixture; adding the first mixture into the second mixture, preserving heat at 70 ℃, stirring and emulsifying at a speed of 3000r/min for 10min, removing the heat source, continuously stirring, cooling to 32 ℃, adding 1g of bradykinin, 3g of gastrodia elata extract and 2g of ginseng extract, and stirring to obtain the sea buckthorn fruit oil composition for repairing skin barrier.
Comparative example 1
The difference between this comparative example and example 1 is that no seabuckthorn fruit oil was added in this comparative example.
Comparative example 2
The difference between this comparative example and example 1 is that bradykinin was not added to this comparative example.
Comparative example 3
The comparative example differs from example 1 in that no collagen was added in the comparative example.
Comparative example 4
The difference between this comparative example and example 1 is that no ceramide was added to this comparative example.
Experimental example
Inventive examples 1, 3 the products prepared in comparative examples 1-4 were subjected to long-term repair function test: volunteers 350 (age 21-52 years), randomized into 7 groups, 50 per group, 7 experimental groups corresponding to example 1, example 3, comparative examples 1-4, and blank group, respectively.
Except for the blank groups, each group was treated with the product prepared by the corresponding group each day after the evening face, and no other cosmetics were used during the experiment.
The moisture, fat content and pH of the face of the subject were measured before and after the experiment, respectively, and the results are shown in table 1.
TABLE 1
The apparent condition of each volunteer after the end of the experiment (15 days) including cases of acne, red swelling, etc., was evaluated and classified into three grades of effective, significant and ineffective according to the effect conditions, and the results are shown in table 2.
Has obvious effect, and the symptom and sign integral decrease is more than or equal to 80 percent.
Effective in reducing symptom and sign integral by more than or equal to 30% and less than 80%.
It is ineffective, and its symptoms and signs are reduced by less than 30%.
TABLE 2
As can be seen from table 2, the products prepared in examples 1 and 3 of the present application have good effects on repairing skin barrier, and the comparative examples 1, 2 and 4 all have improved effect compared to the blank group, but the comparative example 3 does not add collagen, which has effects in some methods even inferior to the blank, indicating that blind application of cosmetics without conditioning skin permeability may adversely affect skin.
Note that: all subjects had no adverse events after the experiment.
In summary, the seabuckthorn fruit oil composition for repairing skin barrier and the preparation method thereof provided by the embodiment of the application have the following advantages:
the application performs synergistic repair of the skin barrier from 3 aspects: 1. the sea buckthorn fruit oil is adopted to play a role in diminishing inflammation and calming, the gastrodia elata extract plays a role in dredging channels and collaterals and promoting circulation, and damaged cells and precipitated pigment in the skin are discharged out of the body along with metabolism of the body by a lymphatic system; 2. the application adopts collagen, can stimulate the regeneration capability of collagen parent cells to strengthen, and finally achieves the regeneration result of collagen fibers. The aging of all tissues of the face is closely related to the loss of collagen, the regeneration of the collagen is stimulated to restore the adipose tissues, the facial support ligament is elastically restored, the fascia is tightened, the skin color and the elasticity are restored, and the like. 3. On the basis of solving the skin permeability, the water content of the skin is maintained by utilizing the strong capability of the ceramide for associating water molecules and the network structure formed in the stratum corneum, and the water-oil balance of the skin is maintained by combining other moisturizing components, so that a faster and better skin repairing effect is achieved.
The embodiments described above are some, but not all embodiments of the application. The detailed description of the embodiments of the application is not intended to limit the scope of the application, as claimed, but is merely representative of selected embodiments of the application. All other embodiments, which can be made by those skilled in the art based on the embodiments of the application without making any inventive effort, are intended to be within the scope of the application.
Claims (9)
1. The sea buckthorn fruit oil composition for repairing skin barrier is characterized by being prepared from the following raw materials in parts by weight: 2-5 parts of glycerol, 2-6 parts of sea buckthorn fruit oil, 2-5 parts of hydrolyzed sodium hyaluronate, 0.5-2 parts of lecithin, 1-5 parts of disodium ethylenediamine tetraacetate, 1-5 parts of butanediol, 0.5-3 parts of ceramide, 3-8 parts of collagen, 0.5-2 parts of trehalose, 0.5-2 parts of bradykinin, 0.2-1 part of inositol, 1-5 parts of gastrodia elata extract, 1-5 parts of ginseng extract and 60-75 parts of deionized water.
2. The seabuckthorn fruit oil composition for repairing skin barrier according to claim 1, which is characterized by being prepared from the following raw materials in parts by weight: 3 parts of glycerin, 4 parts of sea buckthorn fruit oil, 3 parts of hydrolyzed sodium hyaluronate, 1 part of lecithin, 2 parts of disodium edentate, 2 parts of butanediol, 2 parts of ceramide, 5 parts of collagen, 1 part of trehalose, 1 part of bradykinin, 0.5 part of inositol, 4 parts of gastrodia elata extract, 4 parts of ginseng extract and 70 parts of deionized water.
3. The seabuckthorn fruit oil composition for repairing skin barrier according to claim 1 or 2, wherein the preparation method of the gastrodia elata extract and ginseng extract is as follows:
drying and crushing rhizoma Gastrodiae or Ginseng radix, adding ethanol, extracting with ethanol, and collecting ethanol extractive solution;
concentrating the ethanol extract to obtain fluid extract, adding deionized water, stirring, eluting with deionized water, eluting with ethanol, collecting ethanol eluate, concentrating to obtain fluid extract, and drying.
4. A seabuckthorn fruit oil composition for repairing skin barrier according to claim 3, wherein the drying temperature is 50-60 ℃, the crushed seabuckthorn fruit oil composition is sieved by a 50-100 mesh sieve, the concentration of ethanol is 90-95%, and the mass ratio of gastrodia elata or ginseng to ethanol is 1: (5-10).
5. A seabuckthorn fruit oil composition for repairing skin barrier according to claim 1 or 2, characterized in that the preparation method of the seabuckthorn fruit oil comprises the following steps: pulping fructus Hippophae, adding salt, stirring, centrifuging, and extracting upper layer juice.
6. The seabuckthorn fruit oil composition for repairing skin barrier according to claim 5, wherein the mass ratio of salt to seabuckthorn fruit is (1-3): 100, wherein the centrifugation temperature is 40-50 ℃, the centrifugation speed is 7000-8000r/min, and the centrifugation time is 3-8min.
7. A method of preparing a seabuckthorn fruit oil composition for repairing skin barrier according to any one of claims 1 to 6, comprising the steps of:
mixing glycerol, oleum Hippophae and lecithin, and heating to 70-80deg.C to obtain a first mixture;
deionized water, hydrolyzed sodium hyaluronate, disodium ethylenediamine tetraacetate, butanediol, ceramide, collagen, trehalose and inositol are heated to 85-90 ℃ to obtain a second mixture;
adding the first mixture into the second mixture, stirring for emulsification, cooling, adding bradykinin, rhizoma Gastrodiae extract and Ginseng radix extract, and stirring to obtain the fructus Hippophae oil composition for repairing skin barrier.
8. The method for preparing a seabuckthorn fruit oil composition for repairing skin barrier according to claim 7, wherein the temperature of stirring and emulsifying is 60-70 ℃, the stirring speed is 2000-3000r/min, and the stirring time is 10-15min.
9. The method of preparing a seabuckthorn fruit oil composition for repairing skin barrier according to claim 7, wherein the temperature after cooling is 25-40 ℃.
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| DE202006019184U1 (en) * | 2006-12-15 | 2007-04-19 | Koppe, Silke | Moisturizing sea buckthorn skin care gel, useful to nourish and clean skin that is damaged by cancer therapy, comprises wax and fat; vitamin; vegetable hydrolate; moisturizing and anti-allergic active substance, pH-regulator and buffer |
| CN107693402A (en) * | 2017-11-17 | 2018-02-16 | 广州今盛美精细化工有限公司 | A kind of fructus hippophae moisturizing Face-protecting mask and preparation method thereof |
| CN108635263A (en) * | 2018-06-14 | 2018-10-12 | 厦门市艾康利生物科技有限公司 | A kind of skin care compositions and preparation method thereof rich in Seabuckthorn Oil |
| CN109568190A (en) * | 2018-12-30 | 2019-04-05 | 广州瑞誉化工科技有限公司 | A kind of skin composition and its preparation method and application for repairing sunburn |
| CN113143792A (en) * | 2021-03-23 | 2021-07-23 | 杭州帝通生物科技有限公司 | Moisturizing repair cream for repairing skin barrier and preparation method thereof |
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- 2022-10-21 CN CN202211296878.5A patent/CN115463076B/en active Active
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| DE202006019184U1 (en) * | 2006-12-15 | 2007-04-19 | Koppe, Silke | Moisturizing sea buckthorn skin care gel, useful to nourish and clean skin that is damaged by cancer therapy, comprises wax and fat; vitamin; vegetable hydrolate; moisturizing and anti-allergic active substance, pH-regulator and buffer |
| CN107693402A (en) * | 2017-11-17 | 2018-02-16 | 广州今盛美精细化工有限公司 | A kind of fructus hippophae moisturizing Face-protecting mask and preparation method thereof |
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| CN113143792A (en) * | 2021-03-23 | 2021-07-23 | 杭州帝通生物科技有限公司 | Moisturizing repair cream for repairing skin barrier and preparation method thereof |
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