CN115427396A - 用于预防或治疗脂质代谢相关疾病的化合物 - Google Patents

用于预防或治疗脂质代谢相关疾病的化合物 Download PDF

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CN115427396A
CN115427396A CN202180030221.1A CN202180030221A CN115427396A CN 115427396 A CN115427396 A CN 115427396A CN 202180030221 A CN202180030221 A CN 202180030221A CN 115427396 A CN115427396 A CN 115427396A
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alkyl
cycloalkyl
radical
alkylene
halogen
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鲁伯埙
付玉华
丁澦
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Fudan University
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Abstract

本发明涉及生物医药领域，并且具体地涉及将能够结合LC3的结构与能够结合脂滴的结构通过共价连接连接在一起，从而形成的“LC3结合部分‑脂滴结合部分‑偶联物”，其药学上可接受的盐、立体异构体、溶剂化物、多晶型、互变异构体、同位素化合物、代谢产物或前药，以及在制备用于预防或治疗脂质代谢相关疾病的药物中的用途。

Description

PCT国内申请，说明书已公开。

Claims (27)

  1. PCT国内申请，权利要求书已公开。
CN202180030221.1A 2020-04-23 2021-04-23 用于预防或治疗脂质代谢相关疾病的化合物 Pending CN115427396A (zh)

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CN2020103289112 2020-04-23
CN202010328911.2A CN113549000A (zh) 2020-04-23 2020-04-23 用于预防或治疗脂质代谢相关疾病的化合物
PCT/CN2021/089453 WO2021213518A1 (zh) 2020-04-23 2021-04-23 用于预防或治疗脂质代谢相关疾病的化合物

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WO2022140246A1 (en) * 2020-12-21 2022-06-30 Hangzhou Jijing Pharmaceutical Technology Limited Methods and compounds for targeted autophagy
CN114790185B (zh) * 2022-04-29 2023-09-19 五邑大学 一种香豆素肟酯类化合物或其药学上可接受的盐及其制备方法和应用

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