CN115398304A - 观察装置和观察方法 - Google Patents
观察装置和观察方法 Download PDFInfo
- Publication number
- CN115398304A CN115398304A CN202180026046.9A CN202180026046A CN115398304A CN 115398304 A CN115398304 A CN 115398304A CN 202180026046 A CN202180026046 A CN 202180026046A CN 115398304 A CN115398304 A CN 115398304A
- Authority
- CN
- China
- Prior art keywords
- optical system
- observation
- light
- polarization
- prism
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 238000000034 method Methods 0.000 title claims description 36
- 230000003287 optical effect Effects 0.000 claims abstract description 248
- 230000010287 polarization Effects 0.000 claims abstract description 173
- 238000003384 imaging method Methods 0.000 claims abstract description 115
- 238000004458 analytical method Methods 0.000 claims abstract description 16
- 238000006243 chemical reaction Methods 0.000 claims description 79
- 230000001678 irradiating effect Effects 0.000 claims description 2
- 230000004044 response Effects 0.000 claims description 2
- 238000010586 diagram Methods 0.000 description 19
- 230000004907 flux Effects 0.000 description 18
- 238000007796 conventional method Methods 0.000 description 11
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- 230000014509 gene expression Effects 0.000 description 3
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Images
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/10—Investigating individual particles
- G01N15/14—Optical investigation techniques, e.g. flow cytometry
- G01N15/1434—Optical arrangements
-
- G—PHYSICS
- G02—OPTICS
- G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
- G02B21/00—Microscopes
- G02B21/06—Means for illuminating specimens
-
- G—PHYSICS
- G02—OPTICS
- G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
- G02B21/00—Microscopes
- G02B21/06—Means for illuminating specimens
- G02B21/08—Condensers
- G02B21/14—Condensers affording illumination for phase-contrast observation
-
- G—PHYSICS
- G02—OPTICS
- G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
- G02B21/00—Microscopes
- G02B21/36—Microscopes arranged for photographic purposes or projection purposes or digital imaging or video purposes including associated control and data processing arrangements
- G02B21/361—Optical details, e.g. image relay to the camera or image sensor
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/10—Investigating individual particles
- G01N2015/1006—Investigating individual particles for cytology
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/10—Investigating individual particles
- G01N15/14—Optical investigation techniques, e.g. flow cytometry
- G01N2015/1497—Particle shape
-
- G—PHYSICS
- G02—OPTICS
- G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
- G02B5/00—Optical elements other than lenses
- G02B5/30—Polarising elements
Landscapes
- Physics & Mathematics (AREA)
- Chemical & Material Sciences (AREA)
- General Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Optics & Photonics (AREA)
- Engineering & Computer Science (AREA)
- Multimedia (AREA)
- Health & Medical Sciences (AREA)
- Dispersion Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Microscoopes, Condenser (AREA)
- Polarising Elements (AREA)
- Investigating Or Analysing Materials By Optical Means (AREA)
- Instruments For Measurement Of Length By Optical Means (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2020070805A JP7307027B2 (ja) | 2020-04-10 | 2020-04-10 | 観察装置および観察方法 |
JP2020-070805 | 2020-04-10 | ||
PCT/JP2021/008235 WO2021205783A1 (ja) | 2020-04-10 | 2021-03-03 | 観察装置および観察方法 |
Publications (1)
Publication Number | Publication Date |
---|---|
CN115398304A true CN115398304A (zh) | 2022-11-25 |
Family
ID=78023176
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN202180026046.9A Pending CN115398304A (zh) | 2020-04-10 | 2021-03-03 | 观察装置和观察方法 |
Country Status (6)
Country | Link |
---|---|
US (1) | US20230152206A1 (de) |
EP (1) | EP4113188A4 (de) |
JP (1) | JP7307027B2 (de) |
KR (1) | KR20220162699A (de) |
CN (1) | CN115398304A (de) |
WO (1) | WO2021205783A1 (de) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2024022034A (ja) * | 2022-08-05 | 2024-02-16 | 浜松ホトニクス株式会社 | プログラムされた細胞死を起こした細胞の領域を決定する方法、決定部を備える装置及び決定ステップを含む情報処理プログラム |
JP2024044416A (ja) * | 2022-09-21 | 2024-04-02 | 株式会社Screenホールディングス | 勾配光干渉顕微鏡 |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH05232384A (ja) * | 1992-02-18 | 1993-09-10 | Olympus Optical Co Ltd | 干渉顕微鏡 |
JP4867354B2 (ja) | 2006-01-16 | 2012-02-01 | 横河電機株式会社 | 共焦点顕微鏡 |
WO2008105156A1 (ja) | 2007-02-28 | 2008-09-04 | Photonic Lattice, Inc. | 偏光イメージング装置,及び微分干渉顕微鏡 |
JP5371694B2 (ja) * | 2009-10-26 | 2013-12-18 | オリンパス株式会社 | 顕微鏡接続ユニットおよび顕微鏡システム |
JP6124774B2 (ja) | 2013-03-22 | 2017-05-10 | オリンパス株式会社 | 位相分布計測方法、及び、位相分布計測装置 |
US10132609B2 (en) | 2016-11-22 | 2018-11-20 | The Board Of Trustees Of The University Of Illinois | Gradient light interference microscopy for 3D imaging of unlabeled specimens |
-
2020
- 2020-04-10 JP JP2020070805A patent/JP7307027B2/ja active Active
-
2021
- 2021-03-03 EP EP21784072.7A patent/EP4113188A4/de active Pending
- 2021-03-03 US US17/917,044 patent/US20230152206A1/en active Pending
- 2021-03-03 WO PCT/JP2021/008235 patent/WO2021205783A1/ja unknown
- 2021-03-03 KR KR1020227032682A patent/KR20220162699A/ko unknown
- 2021-03-03 CN CN202180026046.9A patent/CN115398304A/zh active Pending
Also Published As
Publication number | Publication date |
---|---|
US20230152206A1 (en) | 2023-05-18 |
KR20220162699A (ko) | 2022-12-08 |
WO2021205783A1 (ja) | 2021-10-14 |
JP7307027B2 (ja) | 2023-07-11 |
EP4113188A4 (de) | 2024-04-24 |
JP2021167880A (ja) | 2021-10-21 |
EP4113188A1 (de) | 2023-01-04 |
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