CN115364165A - A topical Chinese medicinal composition for treating prostatitis, and its preparation method - Google Patents

A topical Chinese medicinal composition for treating prostatitis, and its preparation method Download PDF

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CN115364165A
CN115364165A CN202011172832.3A CN202011172832A CN115364165A CN 115364165 A CN115364165 A CN 115364165A CN 202011172832 A CN202011172832 A CN 202011172832A CN 115364165 A CN115364165 A CN 115364165A
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chinese medicine
traditional chinese
medicine composition
treating prostatitis
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刘彩林
刘吉云
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Shanghai Leiyun Biotechnology Co ltd
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Shanghai Leiyun Biotechnology Co ltd
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    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/29—Berberidaceae (Barberry family), e.g. barberry, cohosh or mayapple
    • A61K36/296—Epimedium
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/36—Caryophyllaceae (Pink family), e.g. babysbreath or soapwort
    • A—HUMAN NECESSITIES
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    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/481—Astragalus (milkvetch)
    • A—HUMAN NECESSITIES
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    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
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    • A61K36/185—Magnoliopsida (dicotyledons)
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    • A61K2236/30—Extraction of the material
    • A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/333—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using mixed solvents, e.g. 70% EtOH

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Abstract

The invention discloses an external traditional Chinese medicine composition for treating prostatitis and a preparation method thereof. A traditional Chinese medicine composition for external use for treating prostatitis is composed of the following substances in parts by mass: 60-70 parts of white spirit, 2-5 parts of plantain herb, 1-5 parts of phellodendron bark, 3-5 parts of cowherb seed, 3-10 parts of combined spicebush root, 3-7 parts of corydalis tuber, 5-12 parts of longspur epimedium, 3-5 parts of astragalus root, 1-3 parts of ligusticum chuanxiong hort, 3-5 parts of common yam rhizome, 5-10 parts of oyster, 3-7 parts of safflower, 0.5-1 part of artificial musk and 0.5-1 part of auxiliary materials. The external herbal spraying liquid is developed on the basis of improving the traditional Chinese medicine classic prescription and applying the latest modern scientific extraction technology by referring to and improving the brewing production process of the traditional Chinese medicine, so that the effective ingredients of the herbal are greatly improved, and the external herbal spraying liquid has the characteristics of safety, reliability, obvious effect, convenience in use, no toxic or side effect and the like.

Description

A topical Chinese medicinal composition for treating prostatitis, and its preparation method
Technical Field
The invention relates to an external traditional Chinese medicine composition for treating prostatitis and a preparation method thereof, belonging to the technical field of traditional Chinese medicines.
Background
Prostatitis (prostatis) refers to a prostate disease caused by various complex causes and mainly clinically manifested by urethral irritation symptoms and chronic pelvic pain. Prostatitis is a common disease in urology surgery, and accounts for the first time among male patients under 50 years old in urology surgery. Although the incidence of prostatitis is high, the cause of prostatitis is still unclear, especially non-bacterial prostatitis, and thus the treatment is mainly to improve symptoms. 1995. The National Institute of Health (NIH) of the year established a new method for classifying prostatitis, type I: corresponding to acute bacterial prostatitis in the traditional classification method, type II: corresponding to chronic bacterial prostatitis in the traditional classification method, type III: chronic prostatitis/chronic pelvic pain syndrome, type iv: asymptomatic prostatitis. Among them, nonbacterial prostatitis is much more common than bacterial prostatitis.
The Chinese herbal medicine preparation is sprayed on meridian points to achieve targeted nutrition and body care by applying the meridian theory of the traditional Chinese medicine. The Chinese herbal medicine preparation stimulates local meridian points, produces the relative advantages of the concentration of the effective components of the herbaceous plants in local parts, and plays the maximum role of nutrition nursing through the absorption and the transportation of tiny blood vessels.
Disclosure of Invention
The traditional Chinese medicine composition disclosed by the invention is an external herbal plant spraying liquid developed on the basis of improving the traditional Chinese medicine classic prescription and applying the latest modern scientific extraction technology by referring to and improving the brewing production process of the traditional Chinese medicine, so that the effective ingredients of the herbal plants are greatly improved, and the traditional Chinese medicine composition has the characteristics of safety, reliability, obvious effect, convenience in use, no toxic or side effect and the like.
The invention solves the technical problems by the following technical means: an external traditional Chinese medicine composition for treating prostatitis consists of the following substances in parts by mass: 60-70 parts of white spirit, 2-5 parts of plantain herb, 1-5 parts of phellodendron, 3-5 parts of cowherb seed, 3-10 parts of combined spicebush root, 3-7 parts of corydalis tuber, 5-12 parts of longspur epimedium, 3-5 parts of astragalus root, 1-3 parts of ligusticum wallichii, 3-5 parts of common yam rhizome, 5-10 parts of oyster, 3-7 parts of safflower, 0.5-1 part of artificial musk and 0.5-1 part of auxiliary material.
A topical Chinese medicinal composition for treating prostatitis is prepared by drying herba plantaginis, cortex Phellodendri, semen Vaccariae, radix Linderae, rhizoma corydalis, herba Epimedii, radix astragali, rhizoma Ligustici Chuanxiong, rhizoma Dioscoreae, concha Ostreae, carthami flos and artificial Moschus, pulverizing in a pulverizer, sieving with 100-200 mesh sieve, collecting undersize product, sieving the oversize product, pulverizing, sieving, adding Chinese liquor into undersize product, adding adjuvants, extracting at 80-120 deg.C for 3-5 hr, refluxing with reflux condenser, cooling, filtering, and packaging the filtrate.
The auxiliary materials are salt and edible soda, the mass ratio of the salt to the edible soda is 1:2-3, and the alcohol degree of the white spirit is more than 60 degrees.
The cooling temperature of the reflux condenser pipe is 30-50 ℃.
And filtering by adopting a microporous filter until the content of water-insoluble substances in the filtrate is lower than 50ppm.
And the filter residue is discarded after two times of extraction, and the extract liquor of the filter residue after the second time of extraction is returned for the first time of extraction.
The stock solution of this patent is brown liquid. The medicine has slight Chinese herbal medicine smell when sprayed on the surface of skin.
The traditional Chinese medicine composition disclosed by the invention is an external herbal plant spraying liquid developed on the basis of improving the traditional Chinese medicine classic prescription and applying the latest modern scientific extraction technology by referring to and improving the brewing production process of the traditional Chinese medicine, so that the effective ingredients of the herbal plants are greatly improved, and the traditional Chinese medicine composition has the characteristics of safety, reliability, obvious effect, convenience in use, no toxic or side effect and the like.
The method adopts alcohol as a carrier, adopts a reflux mode for extraction at a lower temperature, and simultaneously adds auxiliary materials (salt and edible soda), so that the extraction rate can be further improved, and cell walls can be more effectively destroyed, thereby dissociating effective substances.
The medicament is applicable to nutritional nursing such as frequent micturition, urgent micturition, sleep diuresis, urine obstruction and the like caused by bladder and urethra discomfort and the like.
The beneficial effects of the invention are: on the basis of improving the traditional Chinese medicine classic prescription, the latest modern scientific extraction technology is applied, the process of brewing and producing the medicinal liquor in the traditional Chinese medicine is referred and promoted, and the externally applied herbal spraying liquid developed on the basis greatly improves the effective ingredients of the herbal plants and has the characteristics of safety, reliability, obvious effect, convenient use, no toxic or side effect and the like
Drawings
Fig. 1 is a schematic view of the application area of the agent of the present invention.
Detailed Description
The invention will be described in detail with reference to specific embodiments and accompanying drawings, wherein the external traditional Chinese medicine composition for treating prostatitis comprises the following components in parts by mass: 60-70 parts of white spirit, 2-5 parts of plantain herb, 1-5 parts of phellodendron bark, 3-5 parts of cowherb seed, 3-10 parts of combined spicebush root, 3-7 parts of corydalis tuber, 5-12 parts of longspur epimedium, 3-5 parts of astragalus root, 1-3 parts of ligusticum chuanxiong hort, 3-5 parts of common yam rhizome, 5-10 parts of oyster, 3-7 parts of safflower, 0.5-1 part of artificial musk and 0.5-1 part of auxiliary materials.
A topical Chinese medicinal composition for treating prostatitis is prepared by drying herba plantaginis, cortex Phellodendri, semen Vaccariae, radix Linderae, rhizoma corydalis, herba Epimedii, radix astragali, rhizoma Ligustici Chuanxiong, rhizoma Dioscoreae, concha Ostreae, carthami flos and artificial Moschus, pulverizing in a pulverizer, sieving with 100-200 mesh sieve, collecting undersize product, sieving the oversize product, pulverizing, sieving, adding Chinese liquor into undersize product, adding adjuvants, extracting at 80-120 deg.C for 3-5 hr, refluxing with reflux condenser, cooling, filtering, and packaging the filtrate.
The auxiliary materials are salt and edible soda, the mass ratio of the salt to the edible soda is 1:2-3, and the alcohol degree of the white spirit is more than 60 degrees.
The cooling temperature of the reflux condensing pipe is 30-50 ℃.
And filtering by adopting a microporous filter until the content of water-insoluble substances in the filtrate is lower than 50ppm.
And the filter residue is discarded after two extractions, and the extract liquid of the filter residue after the second extraction is returned for the first extraction.
Example 1
The main components of the invention are as follows: chinese liquor, plantain herb, phellodendron bark, cowherb seed, combined spicebush root, corydalis tuber, longspur epimedium, astragalus root, ligusticum wallichii, common yam rhizome, oyster, safflower, artificial musk and the like.
Contains a small amount of productive auxiliary material components: salt, edible soda, etc.
The application range is as follows: it is suitable for the nutritional care of frequent micturition, urgent micturition, polyuria, and dysuria caused by bladder and urethra discomfort.
The using method comprises the following steps: for external application, spray-coating the lower abdomen area (shown in fig. 1) below navel and perineum area (at low room temperature, blow-drying with electric blower is recommended) every morning and before sleep.
Note that:
1. the product is an external spray, which is contraindicated for oral administration
2. It should not be used in the same place with other topical preparations.
3. It is contraindicated for skin ulceration
Adverse reactions: very few patients (those with alcohol allergy use with caution) have local skin allergy, and the skin allergy will disappear after stopping using the composition.
Finally, the above embodiments are only for illustrating the technical solutions of the present invention and not for limiting, although the present invention has been described in detail with reference to the preferred embodiments, it should be understood by those skilled in the art that modifications or equivalent substitutions may be made to the technical solutions of the present invention without departing from the spirit and scope of the technical solutions of the present invention, and all of them should be covered in the claims of the present invention.

Claims (6)

1. A traditional Chinese medicine composition for external use for treating prostatitis is characterized in that: the feed consists of the following substances in parts by mass: 60-70 parts of white spirit, 2-5 parts of plantain herb, 1-5 parts of golden cypress, 3-5 parts of cowherb seed, 3-10 parts of combined spicebush root, 3-7 parts of corydalis tuber, 5-12 parts of longspur epimedium, 3-5 parts of astragalus root, 1-3 parts of ligusticum wallichii, 3-5 parts of common yam rhizome, 5-10 parts of oyster, 3-7 parts of safflower, 0.5-1 part of artificial musk and 0.5-1 part of auxiliary material.
2. A preparation method of an external traditional Chinese medicine composition for treating prostatitis is characterized by comprising the following steps: drying herba plantaginis, cortex Phellodendri, semen Vaccariae, radix Linderae, rhizoma corydalis, herba Epimedii, radix astragali, rhizoma Ligustici Chuanxiong, rhizoma Dioscoreae, concha Ostreae, carthami flos and artificial Moschus, pulverizing in a pulverizer, sieving with 100-200 mesh sieve, collecting undersize product, sieving after the oversize product returns to continue pulverizing, adding Chinese liquor into undersize product, adding adjuvants, extracting at 80-120 deg.C for 3-5 hr, refluxing with reflux condenser tube, cooling, filtering, and bottling the filtrate.
3. The external traditional Chinese medicine composition for treating prostatitis according to claim 1, which is characterized in that: the auxiliary materials are salt and edible soda, the mass ratio of the salt to the edible soda is 1:2-3, and the alcohol degree of the white spirit is more than 60 degrees.
4. The preparation method of the external traditional Chinese medicine composition for treating prostatitis according to claim 2, which is characterized by comprising the following steps: the cooling temperature of the reflux condensing pipe is 30-50 ℃.
5. The preparation method of the external traditional Chinese medicine composition for treating prostatitis according to claim 2, which is characterized by comprising the following steps: and filtering by adopting a microporous filter until the content of water-insoluble substances in the filtrate is lower than 50ppm.
6. The preparation method of the external traditional Chinese medicine composition for treating prostatitis according to claim 2, which is characterized by comprising the following steps: and the filter residue is discarded after two times of extraction, and the extract liquor of the filter residue after the second time of extraction is returned for the first time of extraction.
CN202011172832.3A 2020-10-28 2020-10-28 A topical Chinese medicinal composition for treating prostatitis, and its preparation method Pending CN115364165A (en)

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Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101700327A (en) * 2009-11-27 2010-05-05 通化斯威药业股份有限公司 Drug for treating prostatitis and preparation method
CN101721528A (en) * 2009-12-30 2010-06-09 长春中医药大学 Medicine composition for treating chronic prostatitis
CN102847023A (en) * 2012-10-08 2013-01-02 通化东宝药业股份有限公司 Capsule for treating chronic prostatitis
CN103656533A (en) * 2013-12-30 2014-03-26 王雪雁 Chinese medicinal composition for treating chronic prostatitis
CN103656329A (en) * 2014-01-08 2014-03-26 王雪雁 Medicinal liquor for treating chronic prostatitis
CN105148135A (en) * 2015-10-08 2015-12-16 温州医科大学附属第一医院 Traditional Chinese medicine preparation for treating chronic prostatitis

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101700327A (en) * 2009-11-27 2010-05-05 通化斯威药业股份有限公司 Drug for treating prostatitis and preparation method
CN101721528A (en) * 2009-12-30 2010-06-09 长春中医药大学 Medicine composition for treating chronic prostatitis
CN102847023A (en) * 2012-10-08 2013-01-02 通化东宝药业股份有限公司 Capsule for treating chronic prostatitis
CN103656533A (en) * 2013-12-30 2014-03-26 王雪雁 Chinese medicinal composition for treating chronic prostatitis
CN103656329A (en) * 2014-01-08 2014-03-26 王雪雁 Medicinal liquor for treating chronic prostatitis
CN105148135A (en) * 2015-10-08 2015-12-16 温州医科大学附属第一医院 Traditional Chinese medicine preparation for treating chronic prostatitis

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
周安方;: "尿频症应如何辨证施治?" *

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