CN115350257A - Production process of ginseng and lotus capsule and raw material extraction device - Google Patents

Abstract

The application relates to a ginseng lotus capsule production process and a raw material extraction device, which relate to the field of Chinese patent medicine production and processing and comprise the following steps: processing, removing impurities from rhizoma Sparganii, curcumae rhizoma, fructus Psoraleae, radix Sophorae Flavescentis, herba Scutellariae Barbatae, saviae Miltiorrhizae radix, semen Armeniacae amarum, semen lablab album, radix Sophorae Tonkinensis, radix Stephaniae Tetrandrae and mume fructus, and cleaning; extracting, namely extracting the prepared medicinal materials after ultrasonic treatment, and then performing concentration, alcohol precipitation, concentration, drying, crushing, granulation, filling and other steps to obtain the ginseng and lotus capsule. The raw material extraction device and the process are combined, so that the extraction process of the ginseng lotus capsule is further simplified, the extraction efficiency is obviously improved, and the yield of the product is improved compared with the conventional extraction process.

Description

Production process of ginseng and lotus capsule and raw material extraction device

Technical Field

The application relates to the field of medicine production, in particular to a ginseng lotus capsule production process and a raw material extraction device.

Background

The Shenlian capsule is a Chinese patent medicine prepared from eleven medicinal materials of lightyellow sophora root, subprostrate sophora, barbed skullcap herb, fourstamen stephania root, common burreed rhizome, zedoary, red-rooted salvia root, malaytea scurfpea fruit, bitter apricot seed, dark plum and white hyacinth bean serving as raw materials, has the effects of clearing away heat and toxic materials, promoting blood circulation to remove blood stasis, and softening and resolving hard mass, and is mainly used for patients with middle-and-late lung cancer and gastric cancer caused by qi and blood stasis and heat-toxin internal resistance.

At present, ginseng lotus capsules are produced by cleaning all traditional Chinese medicinal materials and then extracting the traditional Chinese medicinal materials, extracting effective components in the medicinal materials, concentrating and drying an extracting solution to obtain dry paste prepared by the ginseng lotus capsules, crushing the dry paste, granulating and filling the dry paste into capsules. In the whole process, the key of the whole production process is how to extract the effective components in the medicinal materials. The current extraction process generally comprises the steps of cleaning the medicinal materials, cutting into small blocks, mixing all the medicinal materials, carrying out water extraction, and repeatedly adding water for extraction to obtain an extracting solution of the effective components of the medicinal materials. In the process, the traditional Chinese medicinal materials are repeatedly extracted by adding water, so that a large amount of time is required, the extraction time is long, the production period is long, the extraction efficiency is low, and the production efficiency and the cost of the product are influenced.

Disclosure of Invention

In order to promote the extraction efficiency of the chinese-medicinal material of lotus seed capsule production process, this application provides a lotus seed capsule production technology and raw and other materials extraction element.

In a first aspect, the application provides a ginseng lotus capsule production process, which adopts the following technical scheme:

a production process of a Shenlian capsule comprises the following steps:

s1, medicinal material arrangement and processing: taking rhizoma Sparganii, curcumae rhizoma, fructus Psoraleae, radix Sophorae Flavescentis, herba Scutellariae Barbatae, saviae Miltiorrhizae radix, semen Armeniacae amarum, semen lablab album, radix Sophorae Tonkinensis, radix Stephaniae Tetrandrae and mume fructus, removing impurities, and cleaning;

s2, extraction: adding 6 times of water into rhizoma sparganii, curcuma zedoary and fructus psoraleae, distilling and extracting for 5-6 h, collecting volatile oil, then soaking radix sophorae flavescentis, herba scutellariae barbatae, salvia miltiorrhiza, bitter apricot seed, white hyacinth bean, subprostrate sophora, radix stephaniae tetrandrae and smoked plum in 1~2 times of water for 0.5-1h, then mixing with the rhizoma sparganii, curcuma zedoary and fructus psoraleae which are extracted with the volatile oil, carrying out ultrasonic treatment, heating and drying after ultrasonic treatment, then adding 12-15 times of water, extracting for 2-3h, and collecting extracting solution;

s3, concentrating: filtering the extractive solution, and vacuum concentrating to relative density of 1.1 to obtain fluid extract;

s4, alcohol precipitation: adding ethanol into the clear paste until the ethanol content reaches 60%, standing for 10 to 12h for precipitation, and collecting supernatant;

s5, concentrating: vacuum concentrating the supernatant, removing alcohol until the relative density is 1.35 to 1.4 to obtain thick paste;

s6, drying and crushing: vacuum drying the soft extract to obtain dry extract, and pulverizing the dry extract to obtain extract powder;

s7, granulating: mixing the paste powder and silicon dioxide, performing wet granulation, adding 60% ethanol under stirring, granulating, drying, grading, spraying volatile oil, and mixing;

s8, filling: and (4) filling the granules obtained by the whole grain into capsules to obtain the ginseng and lotus capsule, and packaging.

By adopting the technical scheme, the medicinal material is subjected to ultrasonic treatment before extraction, and the cells of the medicinal material tissue are crushed by the cavitation of ultrasonic waves, so that the effective components can be extracted more quickly in the subsequent extraction process. The moist medicinal material carries out drying after ultrasonic treatment, and after the water content in the medicinal material reduced, effective component in the medicinal material can be drawed more easily when the leaching, effectively reduces the required water consumption of later stage leaching in-process, saves extraction time and cost. After ultrasonic treatment, the permeability of the medicinal material histiocyte is higher after drying because the medicinal material histiocyte is broken, and the extraction efficiency can be further improved.

Optionally, in the step S2, the ultrasonic power is 350 to 400w, the ultrasonic frequency is 30 to 60s every 10 seconds, and the total ultrasonic time is 10 to 15min.

By adopting the technical scheme, lower ultrasonic power and longer ultrasonic time are selected, so that the ultrasonic wave can perform effective ultrasonic cavitation on the Chinese medicinal material tissues, and when a large amount of medicinal materials are extracted simultaneously, the ultrasonic extraction is performed at lower frequency for a longer time, and the extraction effect is better.

Optionally, in step S3, the concentration vacuum degree is-0.04 to-0.08 MPa, and the temperature is 60 to 90 ℃.

Optionally, in step S5, the concentration vacuum degree is-0.06 to-0.08 MPa, and the temperature is 60 to 70 ℃.

By adopting the technical scheme, the purpose of concentration in the step S3 is to remove redundant moisture in the extracting solution, so that impurities in the extracting solution are more gathered during subsequent alcohol precipitation, some impurities in the extracting solution are convenient to remove, higher temperature is selected, and the concentration efficiency can be accelerated. The concentration in the step S5 aims to remove the redundant ethanol, the extracted effective components are concentrated into paste, the lower temperature is properly selected, the ethanol can be volatilized and removed at the lower temperature, and the extracted effective components can be prevented from being gelatinized or denatured at the higher temperature in the concentration process.

In a second aspect, the present application provides a raw material extraction device, which adopts the following technical scheme:

a raw material extraction device comprises an extraction tank, wherein the extraction tank comprises an outer tank body and an inner tank body coaxially connected with the outer tank body; a feed inlet and a liquid inlet are formed in the upper part of the outer tank body, the feed inlet is communicated with the inner tank body, a liquid outlet is formed in the lower part of the outer tank body, a plurality of ultrasonic generators are arranged on the outer tank body, and a plurality of heating rods are fixed on the inner wall of the outer tank body; the inner tank is characterized in that a plurality of water filtering holes are formed in the side wall of the inner tank, a stirring assembly is arranged in the inner tank, and a driving piece used for driving the stirring assembly to rotate is arranged on the outer tank.

Through adopting above-mentioned technical scheme, in dropping into the inner tank body with the medicinal material through the feed inlet, water injection in the jar is drawed to the rethread inlet, and water gets into the inner tank body through the water filtering hole on the inner tank lateral wall and soaks the medicinal material, and the medicinal material is through the back of soaking of certain time, opens supersonic generator and carries out the supersound, and the back is accomplished to the supersound, opens the leakage fluid dram and will soak water discharge, then opens the feed inlet and start the heating rod and heat the drying to the medicinal material in the inner tank body. In the drying process, start the inner tank body and rotate, discharge from the feed inlet after the moisture evaporation in the medicinal material, the inner tank body can make inside medicinal material be heated more evenly rotating the in-process, promotes drying efficiency. After the medicinal material is dried, close feed inlet and heating rod, inject water through the inlet and carry out the leaching to the medicinal material, at the leaching in-process, start the inner tank body and rotate to can continue to carry out ultrasonic treatment, promote extraction efficiency. After the medicinal material draws, take out the inner tank body, because seted up the drainage hole on the inner tank body lateral wall, the extract can be followed and drained the entering outer jar of body in the drainage hole, and the medicinal material residue continues to stay in the inner tank body and takes out along with the inner tank body together, and the extract remains in the outer jar of body, carries out subsequent processing. Among the above-mentioned technical scheme, adopt specific device to extract the medicinal material of preparation ginseng lotus capsule, extract the in-process, can promote the efficiency of extracting through ultrasonic treatment, change the conventional complicated operation that extracts in-process water and draw repeatedly many times, reduce the cost that the medicinal material drawed.

Optionally, the stirring subassembly include coaxial rotation connect in the inside (mixing) shaft of the inner tank body, circumference is fixed with helical blade on the (mixing) shaft, through the driving piece drive the (mixing) shaft rotates.

By adopting the technical scheme, in the process of extracting the medicinal materials, the stirring shaft is driven to rotate by the driving piece, the medicinal materials in the inner tank body are overturned and stirred under the driving of the helical blades on stirring, and the medicinal materials are driven to move up and down in the inner tank body, so that the positions of the medicinal materials in the inner tank body are continuously changed and are in more full contact with the extracting solution, and the extraction efficiency is improved; the medicinal material is being stirred the in-process of upset, and helical blade exerts certain backlog effect to it, and the inside liquid of medicinal material is extruded again and is inhaled repeatedly, and the extraction effect is more excellent.

Optionally, a condensation port is formed in the upper portion of the outer tank body, a condensation pipe is connected to the condensation port, and one end, far away from the outer tank body, of the condensation pipe is lower than the condensation port.

Furthermore, a plurality of condensation ports are uniformly arranged on the outer tank body along the circumferential direction; the condenser pipe can be further coated with a cold water pipe, and condensate is injected into the cold water pipe.

By adopting the technical scheme, when medicinal materials are extracted, the common burreed rhizome, the zedoary and the malaytea scurfpea fruit are firstly put into the inner tank body, water is added, heating and distillation are carried out, water vapor in the distillation process is discharged through a condensation port and then enters a condensation pipe to be condensed and collect volatile oil, and 8 medicinal materials such as the lightyellow sophora root, the barbat skullcap and the like are put into the inner tank body to carry out next extraction operation after distillation is finished. Through the setting, carry out the distillation and the extraction collection of medicinal material in same device, reduced the flow that the medicinal material shifted in a plurality of devices, promote extraction efficiency, save manufacturing cost.

Optionally, the bottom of the outer tank body is rotatably connected with a transmission shaft in transmission fit with the stirring shaft, the transmission shaft is coaxially arranged with the stirring shaft, stirring blades are circumferentially fixed on the transmission shaft, and the stirring blades are located below the inner tank body.

By adopting the technical scheme, after extraction is finished, the medicinal material residues are taken out of the outer tank body along with the inner tank body, and the extracting solution is retained at the bottom of the outer tank body for subsequent concentration and alcohol precipitation treatment. During alcohol precipitation, ethanol is added through the liquid inlet, and the stirring blades are driven by the driving transmission shaft to stir the extracting solution to fully contact and react with the ethanol. Through the arrangement, the steps of distillation, extraction and alcohol precipitation of the ginseng and lotus capsule can be carried out in the extraction tank, so that the production efficiency of the ginseng and lotus capsule is further improved.

Optionally, a filter screen is arranged at the liquid outlet.

Through adopting above-mentioned technical scheme, the alcohol precipitation back certain time that stews, impurity deposit in the bottom of the outer jar of body, and the supernatant passes through the liquid outlet and discharges, and the flowing back in-process, impurity mixed in the supernatant is blocked by the filter screen, and then keeps the existence of free impurity in the alcohol precipitation liquid.

In summary, the present application includes at least one of the following beneficial technical effects:

1. according to the production process of the ginseng lotus capsule, ultrasonic treatment is carried out before the medicinal materials are extracted, cells of medicinal material tissues are broken through the cavitation of ultrasonic waves, and effective components in the medicinal materials can be more effectively extracted in the subsequent extraction process; through ultrasonic treatment, the water consumption in the process of extracting the medicinal materials can be reduced, the extraction time is shortened, the extraction efficiency in the production process of the ginseng lotus capsule is improved, and the cost is saved.

2. The application provides a raw and other materials extraction element adopts specific device to extract the medicinal material of preparation ginseng lotus capsule, draws the in-process, can promote the efficiency of extracting through ultrasonic treatment, changes the conventional complicated operation that draws in-process to add water many times and draw repeatedly, reduces the cost that the medicinal material drawed.

3. The application provides a raw and other materials extraction element through set up specific agitating unit and distillation structure at jar internal portion, goes on extracting jar distillation, extraction, concentration and the whole collections of alcohol precipitation technology in the lotus seed capsule production process of will participating, can effectively save the time that the medicinal material transported in various different processing apparatus, avoids the extract to receive the pollution in the transportation to can further promote production efficiency.

Drawings

FIG. 1 is a schematic view of the overall structure of a raw material extraction apparatus according to an embodiment of the present application;

fig. 2 is a sectional view of fig. 1.

Fig. 3 is an exploded view of the drive structure of the stirring shaft and the transmission shaft in fig. 1.

Description of reference numerals: 1. an extraction tank; 11. an outer tank body; 111. a can body; 112. a sealing cover; 113. a liquid inlet; 114. a liquid outlet; 115. a condensation port; 116. a condenser tube; 12. an inner tank body;

2. a support frame;

3. an ultrasonic generator;

4. a heating rod;

5. a drive shaft; 51. a stirring blade; 52. a card slot;

6. a drive motor;

7. a stirring shaft; 71. a helical blade; 72. and (7) clamping blocks.

Detailed Description

The present application is described in further detail below with reference to figures 1-3. It should be noted that, in the following examples, those not specifically mentioned are performed according to conventional conditions or conditions recommended by the manufacturer; the starting materials used in the following examples are all those conventionally commercially available except where specifically noted.

The embodiment of the application discloses raw and other materials extraction element, refer to fig. 1 and fig. 2, raw and other materials extraction element is including drawing jar 1 and being used for supporting the support frame 2 that draws jar 1, it includes outer jar of body 11 and inner tank body 12 to draw jar 1, support frame 2 welds in the 11 bottoms of outer jar of body, inner tank body 12 is fixed in 11 insides of outer jar of body, a plurality of drainage holes have been seted up on the inner tank body 12 lateral wall, the drainage hole is miniature drainage hole, its diameter size only allows water and the material dissolved in aquatic to pass through, the medicinal material residue can not pass through drainage hole. An annular fixture block 72 is formed on the inner side wall of the outer tank 11 for supporting the inner tank 12, the bottom of the inner tank 12 falls on the fixture block 72 at the lower part, the top of the inner tank 12 falls on the fixture block 72 at the upper part, and the inner tank 12 is stably supported by the two fixture blocks 72. The outer tank body 11 comprises a tank body 111 with an open top and a sealing cover 112 hinged to the top of the tank body 111, the open top of the tank body 111 is a feed inlet, the feed inlet is sealed by the sealing cover 112, and the tank body 111 is provided with a plurality of lock catches for locking the sealing tank. A liquid inlet 113 is formed in the upper portion of the tank body 111, a liquid outlet 114 is formed in the bottom of the tank body, sealing elements are mounted at the liquid inlet 113 and the liquid outlet 114 and used for sealing the liquid inlet 113 and the liquid outlet 114, and the sealing elements can be end covers or sealing plugs. An ultrasonic generator 3 is arranged on the outer side wall of the outer tank body 11, a heating rod 4 is fixedly arranged on the inner side wall of the outer tank body 11, the ultrasonic generator 3 and the heating rod 4 are both communicated with an external power supply, and a temperature sensor and a pressure sensor are also arranged in the outer tank body 11.

Referring to fig. 1 and 2, a transmission shaft 5 is coaxially and rotatably connected inside the outer tank 11, a plurality of stirring blades 51 are fixed on the transmission shaft 5, and the bottom end of the transmission shaft 5 extends out of the tank and is rotatably connected with the tank through a sealing bearing. A driving motor 6 is installed at the outside bottom of the outer tank body 11, and the output shaft of the driving motor 6 is coaxially and fixedly connected with the transmission shaft 5. A stirring shaft 7 is coaxially and rotatably connected in the inner tank body 12, helical blades 71 are circumferentially fixed on the stirring shaft 7, and the lower end of the stirring shaft 7 extends out of the inner tank body 12 and then is in transmission fit with the transmission shaft 5. Referring to fig. 3, one end of the stirring shaft 7 close to the transmission shaft 5 is set to be a clamping block 72 in a cross shape, one end corresponding to the transmission shaft 5 is provided with a clamping groove 52 in a cross shape, during installation, the clamping block 72 on the stirring shaft 7 is inserted into the clamping groove 52 on the transmission shaft 5, and then the transmission cooperation of the transmission shaft 5 and the stirring shaft 7 is realized, so that the transmission shaft 5 drives the stirring shaft 7 to rotate when rotating.

Referring to fig. 1 and 2, a condensation port 115 is further formed in the outer tank 11, the condensation port 115 is located at a position, close to the liquid inlet 113, of the outer tank 11, the condensation port 115 is uniformly arranged on the outer tank 11 in the circumferential direction, a condensation pipe 116 is externally connected to the position of the condensation port 115, the condensation pipe 116 is fixed on the outer tank 11, the condensation pipe 116 extends downwards along a direction away from the outer tank 11, one end, away from the outer tank 11, of the condensation port 116 is lower than the condensation port 115, a filter screen can be further installed at the position of the condensation port 115 inside the outer tank 11, and liquid can be further filtered through the filter screen.

The working principle of the raw material extraction device disclosed by the embodiment of the application is as follows: in the extraction stage of the production process of the Shenlian capsule, the three medicinal materials of the rhizoma sparganii, the rhizoma zedoariae and the fructus psoraleae are put into the inner tank body 12 through the feeding hole, the sealing cover 112 is closed, 6 times of water is added through the liquid inlet 113 to immerse the medicinal materials, then heating and stirring are started for distillation, the condensing tube 116 is opened in the distillation process, and the volatile oil is condensed and collected through the condensing tube 116. After distillation, 8 medicinal materials such as radix sophorae flavescentis, herba scutellariae barbatae and the like are put into the inner tank body 12, water is continuously added for soaking, then ultrasonic treatment is carried out, after the ultrasonic treatment is finished, water is discharged through the liquid outlet 114, heating and drying are carried out, water is added for leaching after the drying is finished, and stirring is started in the leaching process. After extraction is finished, the whole inner tank body 12 is taken out, dregs are discharged along with the inner tank body 12, then the outer tank body 11 is sealed for vacuum concentration, and vacuumizing treatment is carried out through the liquid inlet 113. After the concentration is finished, ethanol is added through the liquid inlet 113 for alcohol precipitation treatment, stirring is started during the ethanol addition process to enable the mixture to be uniform, after the alcohol precipitation is finished, the lower-layer precipitate is deposited at the bottom of the outer tank body 11, and the supernatant is discharged through the liquid outlet 114 for subsequent treatment. Because the bottom of the appearance head is provided with the concave pit, and the liquid outlet 114 is arranged at the upper edge of the concave pit, the liquid discharge of the liquid outlet 114 cannot be influenced by the lower-layer sediment. Through above-mentioned setting, can accomplish extraction, concentration and the alcohol precipitation processing of medicinal material in extracting jar 1, the medicinal material need not shift between different equipment to purification efficiency is high.

The technical solution of the present application is further described in detail with reference to the following specific examples.

Examples

Example 1

A production process of a ginseng lotus capsule comprises the following steps:

s1, finishing and processing medicinal materials

Three-edge: removing impurities, grading size, soaking until the solution is completely soaked, taking out, moistening thoroughly, slicing, drying at 75 deg.C, bagging, weighing, labeling, and processing;

zedoary turmeric: removing impurities, slightly soaking, cleaning, steaming to soften, slicing into thick pieces, drying at 65 deg.C, bagging, weighing, labeling, and performing next process;

psoralea fruit: removing impurities, bagging, weighing, labeling, and performing next process for later use;

flavescent sophora root: removing residual root and impurities, cleaning, moistening, slicing, drying at 65 deg.C, bagging, weighing, labeling, and processing;

barbat skullcap: removing impurities, cleaning with water, draining, cutting, drying at 65 deg.C, bagging, weighing, labeling, and performing next process;

red sage root: taking raw medicinal materials, removing impurities and residual stems, cleaning, moistening, slicing or cutting into thick pieces, drying at 65 ℃, bagging, weighing, labeling, and performing the next process for later use;

bitter apricot seeds: removing impurities such as core shells, bagging, weighing, labeling, and performing next process for later use;

white hyacinth bean: removing impurities, bagging, weighing, labeling, and performing next process for later use;

subprostrate sophora root: removing impurities and residual stems, soaking, cleaning, moistening, slicing, drying at 65 deg.C, bagging, weighing, labeling, and processing;

defending: removing impurities, slightly soaking, cleaning, moistening, slicing into thick pieces, drying at 65 deg.C, bagging, weighing, labeling, and processing;

dark plum: removing impurities, scorched and fleshless, cleaning, drying at 65 ℃, bagging, weighing, labeling, and performing next process for later use;

s2, extracting

S21, preparing materials: mixing rhizoma Sparganii 112.5kg, curcumae rhizoma 112.5kg, fructus Psoraleae 105kg, radix Sophorae Flavescentis 150kg, herba Scutellariae Barbatae 119.9kg, saviae Miltiorrhizae radix 74.9kg, semen Armeniacae amarum 60kg, semen lablab album 74.9kg, radix Sophorae Tonkinensis 135kg, radix Stephaniae Tetrandrae 112.5kg, and mume fructus 74.9 kg;

s22, water extraction: putting the three medicinal materials of the rhizoma sparganii, the curcuma zedoary and the fructus psoraleae into an inner tank body of a raw material extraction device, adding 6 times of water, distilling and extracting volatile oil for 6 hours, and recovering the volatile oil; then putting 8 medicinal materials such as radix sophorae flavescentis and herba scutellariae barbatae into the inner tank body, continuously adding water to soak for 0.5h, and then carrying out ultrasonic treatment with the ultrasonic power of 350W and the ultrasonic frequency of 60s every 10 seconds for 10min; after the ultrasonic treatment is finished, discharging the soak solution, heating to 80 ℃, stirring and drying until the water content is lower than 12%, adding 12 times of water, leaching for 2 hours under stirring, then taking out the whole inner tank body, discharging the dregs together with the inner tank body, and collecting the extracting solution at the bottom of the outer tank body;

s23, concentrating: vacuumizing the outer tank body through a liquid inlet to-0.06 to-0.08 Mpa, heating to 70 to 90 ℃, stirring and concentrating until the relative density is 1.10 (60 ℃);

s24, alcohol precipitation: adding ethanol into the outer tank body through a liquid inlet under stirring until the ethanol content reaches 60%, standing for 12h, discharging supernatant, and collecting for later use;

s25, concentration: recovering ethanol from the supernatant after alcohol precipitation in a concentrator, concentrating the supernatant into thick paste with the relative density of 1.35 to 1.40 (60 ℃), and concentrating the thick paste under the vacuum degree of-0.08 Mpa and the temperature of 60 to 70 ℃;

s26, drying: the thick paste is dried in vacuum to form dry paste, the vacuum degree is-0.06 to-0.09 Mpa, and the temperature is 60 to 90 ℃;

s27, crushing the dry paste into dry paste powder on a crusher with a 80-mesh sieve, crushing and bagging for storage; wherein the yield of the dry paste powder is about 46.5 kg and about 4.1 percent;

s3, preparation

S31, material preparation: taking 42.1 kg of dry paste powder, 1.26 kg of volatile oil, 1.4 kg of silicon dioxide and 2 kg of ethanol;

s32, granulating and drying: putting the weighed dry paste powder and silicon dioxide into a wet granulator, setting stirring grade I, cutting grade I, and adding a proper amount of 60% ethanol while stirring; starting stirring the second gear, chopping the second gear, and stirring for 360 seconds until the mixture is fully mixed to obtain a soft material; after being granulated by a swing granulator (granulating in 20 meshes), wet granules are dried in a hot air circulating oven at the drying temperature of 70-80 ℃;

s33, straightening: cooling the dried particles, taking out, and grading in a swing granulator with a sieve mesh of 20 meshes;

s34, total mixing: pouring the granules into a two-dimensional motion mixer, spraying the volatile oil, starting the two-dimensional motion mixer to mix for 30 minutes until the volatile oil is fully and uniformly mixed;

s35, filling: taking a batch of granules after total mixing, filling by using a No. 0 capsule mould, wherein the weight of the granules is 0.5g, the filling quantity difference is controlled to be 0.5g +/-8%, and performing normal production after the appearance and the filling quantity difference of the medicine granules are qualified after trial filling; taking 10 granules every 30 minutes in the normal filling process to check the difference of the filling amount, and checking the appearance of the medicine granules at any time; after filling, filling the filled capsules in clean plastic bags, fastening the filled capsules by a nylon Long Za port belt, hanging a material filling list, marking the contents of the names, the batch numbers, the quantity, the production dates and the like, and storing the material filling list in an intermediate station to obtain the ginseng lotus capsules;

s36, packaging: and carrying out aluminum-plastic packaging or plastic packaging.

Example 2

The difference between this embodiment and embodiment 1 is that the ultrasonic treatment in the leaching process in step S22 specifically includes: putting the three medicinal materials of the rhizoma sparganii, the curcuma zedoary and the fructus psoraleae into an inner tank body of a raw material extraction device, adding 6 times of water, distilling and extracting volatile oil for 6 hours, and recovering the volatile oil; then putting 8 medicinal materials such as radix sophorae flavescentis and herba scutellariae barbatae into the inner tank body, continuously adding water to soak for 0.5h, and then carrying out ultrasonic treatment with the ultrasonic power of 350W and the ultrasonic frequency of 60s every 10 seconds for 10min; after the ultrasonic treatment is finished, discharging the soak solution, heating to 80 ℃, stirring and drying until the water content is lower than 12%, adding 12 times of water, stirring, starting ultrasonic treatment with the ultrasonic power of 200W and the ultrasonic frequency of 30s every other, leaching for 2h, then taking out the whole inner tank body, discharging the medicine dregs along with the inner tank body, and collecting the extracting solution at the bottom of the outer tank body. The remainder was in accordance with example 1. 49.1 kg of dry ointment powder were collected in example 2, and the yield was about 4.4%.

Example 3

The difference between this embodiment and embodiment 1 is that in step S2, the ultrasonic power is 400W, the ultrasonic frequency is 30S every 10S, and the total ultrasonic time is 15min. The remainder was in accordance with example 1. In example 3, 41.5 kg of dry extract powder were obtained, yielding 3.8%.

Comparative example

Comparative example 1

The present comparative example differs from example 1 in that step S22 is as follows:

placing rhizoma Sparganii, curcumae rhizoma, and fructus Psoraleae in an extraction tank, adding 6 times of water, distilling to extract volatile oil for about 6 hr, and recovering volatile oil no less than 12.6 kg. Putting eight medicines such as radix sophorae flavescentis and the like into a multifunctional extraction tank of rhizoma sparganii, curcuma zedoary and fructus psoraleae from which volatile oil is extracted, adding water for extraction for three times, adding 10 times of water for each time, filtering water extract for three times through a pipeline filter for 2 hours for the first time, 1.5 hours for the second time and 1 hour for the third time, and conveying filtrate to a water extract storage tank for temporary storage. The remainder was in accordance with example 1. In comparative example 1, 38 kg of dry ointment powder was collected, with a yield of about 3.4%.

It can be seen from the above examples and comparative examples that, in the technical scheme of the application, the provided raw material extraction device and process are combined, so that the extraction process of the ginseng lotus capsule is further simplified, the extraction efficiency is obviously improved, and the yield of the product is also improved compared with the conventional extraction process.

The above embodiments are preferred embodiments of the present application, and the protection scope of the present application is not limited by the above embodiments, so: all equivalent changes made according to the structure, shape and principle of the present application shall be covered by the protection scope of the present application.

Claims (8)

1. The production process of the ginseng and lotus capsule is characterized by comprising the following steps:

s1, medicinal material arrangement and processing: taking rhizoma Sparganii, curcumae rhizoma, fructus Psoraleae, radix Sophorae Flavescentis, herba Scutellariae Barbatae, saviae Miltiorrhizae radix, semen Armeniacae amarum, semen lablab album, radix Sophorae Tonkinensis, radix Stephaniae Tetrandrae and mume fructus, removing impurities, and cleaning;

s2, extraction: adding 6 times of water into rhizoma sparganii, curcuma zedoary and fructus psoraleae, distilling and extracting for 5-6 h, collecting volatile oil, then soaking radix sophorae flavescentis, herba scutellariae barbatae, salvia miltiorrhiza, bitter apricot seeds, white hyacinth beans, subprostrate sophora, radix stephaniae tetrandrae and dark plum in 1~2 times of water for 0.5-1h, mixing with the rhizoma sparganii, curcuma zedoary and fructus psoraleae with the volatile oil, then carrying out ultrasonic treatment, heating and drying after ultrasonic treatment, then adding 12-15 times of water, extracting for 2-3h, and collecting extracting solution;

s3, concentrating: filtering the extractive solution, and vacuum concentrating to relative density of 1.1 to obtain fluid extract;

s4, alcohol precipitation: adding ethanol into the clear paste until the ethanol content reaches 60%, standing for 10 to 12h for precipitation, and collecting supernatant;

s5, concentrating: vacuum concentrating the supernatant, removing alcohol until the relative density is 1.35 to 1.4 to obtain thick paste;

s6, drying and crushing: vacuum drying the soft extract to obtain dry extract, and pulverizing the dry extract to obtain extract powder;

s7, granulating: mixing the paste powder and silicon dioxide, performing wet granulation, adding 60% ethanol under stirring, granulating, drying, grading, spraying volatile oil, and mixing;

s8, filling: and (4) filling the granules obtained by the whole grain into capsules to obtain the ginseng and lotus capsule, and packaging.

2. The production process of the Shenlian capsule as claimed in claim 1, wherein in step S2, the ultrasonic power is 350 to 400W, the ultrasonic frequency is 30 to 60s every 10 seconds, and the total ultrasonic time is 10 to 15min.

3. The production process of Shenlian capsule as claimed in claim 1, wherein in step S3, the concentration vacuum degree is-0.04 to-0.08 MPa and the temperature is 60 to 90 ℃.

4. The Shenlian capsule production process according to claim 1, wherein the concentration vacuum degree in step S5 is-0.06 to-0.08 MPa and the temperature is 60 to 70 ℃.

5. A raw material extraction device comprises an extraction tank (1), and is characterized in that the extraction tank (1) comprises an outer tank body (11) and an inner tank body (12) coaxially connected with the outer tank body (11); a feed inlet and a liquid inlet (113) are formed in the upper part of the outer tank body (11), the feed inlet is communicated with the inner tank body (12), a liquid outlet (114) is formed in the lower part of the outer tank body (11), a plurality of ultrasonic generators (3) are arranged on the outer tank body (11), and a plurality of heating rods (4) are fixed on the inner wall of the outer tank body (11); a plurality of water filtering holes are formed in the side wall of the inner tank body (12), a stirring assembly is arranged in the inner tank body (12), and a driving piece used for driving the stirring assembly to rotate is arranged on the outer tank body (11).

6. A raw material extraction apparatus as claimed in claim 5, wherein said agitator assembly comprises an agitator shaft (7) coaxially rotatably connected to the inside of said inner tank (12), said agitator shaft (7) having helical blades (71) circumferentially fixed thereto, said agitator shaft (7) being driven to rotate by said drive member.

7. The raw material extraction device as claimed in claim 6, wherein a transmission shaft (5) in transmission fit with the stirring shaft (7) is rotatably connected to the bottom of the outer tank (11), the transmission shaft (5) and the stirring shaft (7) are coaxially arranged, stirring blades (51) are circumferentially fixed on the transmission shaft (5), and the stirring blades (51) are located below the inner tank (12).

8. The raw material extraction device as claimed in claim 5, wherein a condensation port (115) is formed in the upper portion of the outer tank (11), a condensation pipe (116) is connected to the condensation port (115), and one end of the condensation pipe (116) far away from the outer tank (11) is lower than the condensation port (115).

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