CN108324806A - A kind of talcum, caulis clematidis armandii compounding eight positive extract powders production method - Google Patents

A kind of talcum, caulis clematidis armandii compounding eight positive extract powders production method Download PDF

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Publication number
CN108324806A
CN108324806A CN201810198423.7A CN201810198423A CN108324806A CN 108324806 A CN108324806 A CN 108324806A CN 201810198423 A CN201810198423 A CN 201810198423A CN 108324806 A CN108324806 A CN 108324806A
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talcum
rheum officinale
caulis clematidis
clematidis armandii
extract
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Inventor
肖峰
黄河
于峰
赵宁
周占虎
王凡
马奎
张济前
张强
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ANHUI HAISHEN SHOUCHUN PHARMACEUTICAL CO LTD
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ANHUI HAISHEN SHOUCHUN PHARMACEUTICAL CO LTD
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Abstract

The invention discloses a kind of production methods for the eight positive extract powders that talcum, caulis clematidis armandii compound, which is characterized in that the pre-treating technology of raw material is：By dianthus superbus, pivot stores, rush cleans, cutting, rheum officinale is cleaned, is crushed, crushes and obtains rheum officinale coarse powder, caulis clematidis armandii, cape jasmine, Radix Glycyrrhizae are cleaned, are crushed, take medicinal material talcum, removing impurity, cleaned after talcum；Dipping, diacolation, extraction process are：Plantain seed plus alcohol dipping are extracted, plantain seed maceration extract is obtained；Rheum officinale coarse powder is added into ethanol wet, is impregnated, seepage pressure effects obtain rheum officinale percolate；By the dianthus superbus, pivots storage of pre-treatment, talcum, caulis clematidis armandii, cape jasmine, Radix Glycyrrhizae, rush mixed ingredients, adds water to decoct extraction three times, obtain extracting solution；Plantain seed maceration extract, rheum officinale percolate single-action are concentrated to give thick paste, is mixed with gained thick paste after extracting solution economic benefits and social benefits are concentrated and is concentrated to give eight positive medicinal extract, dextrin heating is added, spray drying obtains described eight positive extract powders.

Description

A kind of talcum, caulis clematidis armandii compounding eight positive extract powders production method
Technical field
The present invention relates to medicinal extract fields, and in particular to a kind of talcum, caulis clematidis armandii compounding eight positive extract powders production method.
Background technology
Talcum promoting defecation and urination road, heat-clearing excreting dampness, inducing diuresis for treating strangurtia in eight positive medicinal extract；Clearing away the heart-fire on akebi, lower dampness removing heat, makes damp and hot Heresy gone from urine, two medicine phases close, reducing fever and causing diuresis is treating stranguria, is altogether monarch drug in a prescription.Plantain seed, pivots storage, dianthus superbus, rush reducing fever and causing diuresis It is treating stranguria, it is ministerial drug.Assistant draws hot downlink with cape jasmine promoting diuresis for stranguria；Rheum officinale bitter cold downlink walks internal organs to purge heat.Assistant make with Radix Glycyrrhizae and Middle QI invigorating, coordinating the drug actions of a prescription.All medicine phases are closed, and play heat-clearing, diuresis, treating stranguria work(altogether.For damp invasion of lower energizer, scanty drak urine, leaching drip is puckery Bitterly, dryness of the mouth and throat.
Invention content
The invention mainly solves the technical problem of providing a kind of producers for the eight positive extract powders that talcum, caulis clematidis armandii compound Method, the eight positive extract powders prepared according to this method have the function of heat-clearing, diuresis, treating stranguria.
The technical problems to be solved by the invention are realized using technical solution below：
A kind of talcum, caulis clematidis armandii compounding eight positive extract powders production method, which is characterized in that carry out according to the following steps：
1, the pre-treating technology operation of raw material is as follows：
（1）Dianthus superbus, pivots storage, rush pre-treatment：
It takes medicinal material dianthus superbus, pivot to store, rush, removes impurity, dianthus superbus, the pivot after cleaning are stored, rush is respectively put into turnover and holds In device, it is transferred to cutting area, with Linear reciprocating type medicine slicing machine cutting, length≤8cm after cutting；
（2）Rheum officinale coarse powder pre-treatment：
Medicinal material rheum officinale is taken, impurity is removed, the rheum officinale after cleaning is put into transfer container, fracture area is transferred to, is with mesh size The super power crusher of 1cm is broken, then the pulverizer sieved with 10 mesh crushes；
（3）Talcum pre-treatment：
Medicinal material talcum is taken, impurity is removed, the talcum after cleaning is put into transfer container；
（4）Caulis clematidis armandii, cape jasmine, Radix Glycyrrhizae pre-treatment：
Medicinal material caulis clematidis armandii, cape jasmine, Radix Glycyrrhizae are taken, impurity is removed, caulis clematidis armandii, cape jasmine, the Radix Glycyrrhizae after cleaning, which are respectively put into turnover, to be held In device, it is transferred to fracture area, the super power crusher for being 3cm with mesh size is crushed.
2, dipping, diacolation, extraction process operation are as follows：
Impregnation technology：Plantain seed (stir-fry) is put into extraction tank, 8 times of 25% alcohol dippings of amount are added for 24 hours, collect plantain seed dipping Liquid；
Diacolation technique：The rheum officinale that gained is handled well in step 2 is put into percolate pot, it is wet that 2 times of amount 50% ethyl alcohol progress are first added Profit after impregnating for 24 hours, adds 9 times of 50% ethyl alcohol of amount and carries out diacolation, collect rheum officinale percolate, diacolation speed is 3-5ml/kg.min；
Extraction process：After the dianthus superbus, pivots storage handled well in step 2, talcum, caulis clematidis armandii, cape jasmine, Radix Glycyrrhizae, rush are mixed It is divided into four parts, puts into multi-function extractor, per tank, 12 times of amount drinking water, heating are added in extraction for the first time, and boiling decocts 1.5h, Extracting solution crosses 150 mesh screens, goes to receiver；10 times of amount drinking water are added in second of extraction, and boiling decocts 1h, extracting solution mistake 150 mesh screens, go to receiver；8 times of amount drinking water are added in third time extraction, and boiling decocts 40min, and extracting solution crosses 150 mesh sieve Net goes to receiver, collects extracting solution, steam pressure 0-0.25MPa.
3, concentration operation is as follows：
Single-action concentrates：Single-effect concentrator, vacuum valve and cooling tower are opened, control steam pressure is 0-0.10MPa, and temperature is 60-85 DEG C, vacuum degree is -0.03MPa~-0.09MPa；Respectively to gained plantain seed maceration extract in step 3, rheum officinale percolate into Row concentration is concentrated into the thick paste that relative density is 1.06-1.12；
Economic benefits and social benefits concentrate：Dual-effect concentrator, vacuum valve and cooling tower are opened, control steam pressure is 0-0.10MPa, temperature I 70-90 DEG C of effect, II 65-85 DEG C of effect, vacuum degree is I effect -0.03MPa~-0.06MPa, II imitates -0.05 MPa~-0.08MPa； Gained extracting solution in step 3 is concentrated, thick paste obtained by being concentrated with single-action is concentrated into when relative density is 1.08 and mixes continuation Concentration, it is 1.06-1.12 to be concentrated into relative density, obtains eight positive medicinal extract.
4, spray-drying operation is as follows：
To dextrin is added in eight positive medicinal extract of concentration gained in step 4, medicinal liquid agitating is uniform, is heated to 50-70 DEG C, and inlet air temperature is 180-205 DEG C, leaving air temp is 85-105 DEG C, and material revolution speed is 6-13r/min, and tower pressure interior force is negative pressure, is spray-dried, dry Medicinal extract moisture≤4%.
Wherein dianthus superbus, pivots storage, rheum officinale, talcum, caulis clematidis armandii, cape jasmine, Radix Glycyrrhizae, plantain seed (stir-fry), rush, dextrin mass ratio It is 2:2:2:2:2:2:2:2:1:0.4.
The present invention reaction mechanism and have the beneficial effect that：
Raw material dianthus superbus, pivot storage, rheum officinale, talcum, caulis clematidis armandii, cape jasmine, Radix Glycyrrhizae, rush are taken, impurity is removed, the raw material after cleaning It is put into transfer container, is transferred to fracture area, strength is broken；Plantain seed (stir-fry) is put into extraction tank, alcohol dipping is added, is collected Plantain seed maceration extract；Rheum officinale coarse powder is put into percolate pot, ethyl alcohol is first added and is moistened, ethyl alcohol is added after immersion and is oozed It filters, collects rheum officinale percolate；Then remaining pre-treatment raw material is mixed, boiling water is added to decoct, collect extracting solution；By gained Chinese herbaceous peony Sub- maceration extract, rheum officinale percolate single-action are condensed into thick paste, and extracting solution economic benefits and social benefits are condensed into thick paste, gained thick paste are mixed, paste is added In essence input spray drying basin, heating stirs evenly, obtains described eight positive extract powders；The extracting method can efficiently extract Active ingredient in Chinese medicine, recovery rate is high, and extraction time is short, efficient；The eight positive extract powder has heat-clearing, diuresis, treating stranguria Effect.
Specific implementation mode
In order to make the technical means, the creative features, the aims and the efficiencies achieved by the present invention be easy to understand, tie below Specific embodiment is closed, the present invention is further explained.
Embodiment
A kind of talcum, caulis clematidis armandii compounding eight positive extract powders production method, which is characterized in that carry out according to the following steps：
1, the pre-treating technology operation of raw material is as follows：
（1）Dianthus superbus, pivots storage, rush pre-treatment：
It takes medicinal material dianthus superbus, pivot to store, rush, removes impurity, dianthus superbus, the pivot after cleaning are stored, rush is respectively put into turnover and holds In device, it is transferred to cutting area, with Linear reciprocating type medicine slicing machine cutting, length≤8cm after cutting；
（2）Rheum officinale coarse powder pre-treatment：
Medicinal material rheum officinale is taken, impurity is removed, the rheum officinale after cleaning is put into transfer container, fracture area is transferred to, is with mesh size The super power crusher of 1cm is broken, then the pulverizer sieved with 10 mesh crushes；
（3）Talcum pre-treatment：
Medicinal material talcum is taken, impurity is removed, the talcum after cleaning is put into transfer container；
（4）Caulis clematidis armandii, cape jasmine, Radix Glycyrrhizae pre-treatment：
Medicinal material caulis clematidis armandii, cape jasmine, Radix Glycyrrhizae are taken, impurity is removed, caulis clematidis armandii, cape jasmine, the Radix Glycyrrhizae after cleaning, which are respectively put into turnover, to be held In device, it is transferred to fracture area, the super power crusher for being 3cm with mesh size is crushed.
2, dipping, diacolation, extraction process operation are as follows：
Impregnation technology：Plantain seed (stir-fry) 236kg is put into extraction tank, 8 times of 25% alcohol dippings of amount are added for 24 hours, collect plantain seed Maceration extract；
Diacolation technique：In gained is handled well in step 2 rheum officinale 236kg input percolate pot, will first be added 2 times of 50% ethyl alcohol of amount into Row moistening after impregnating for 24 hours, adds 9 times of 50% ethyl alcohol of amount and carries out diacolation, collect rheum officinale percolate, diacolation speed is 3-5ml/ kg.min；
Extraction process：The dianthus superbus 236kg, pivots handled well in step 2 are stored into 236kg, talcum 236kg, caulis clematidis armandii 236kg, cape jasmine Four parts are divided into after 236kg, Radix Glycyrrhizae 236kg, rush 118kg mixing, puts into multi-function extractor, is extracted for the first time per tank 12 times of amount drinking water, heating are added, boiling decocts 1.5h, and extracting solution crosses 150 mesh screens, goes to receiver；Second of extraction adds Enter 10 times of amount drinking water, boiling decocts 1h, and extracting solution crosses 150 mesh screens, goes to receiver；8 times of amount drinks are added in third time extraction With water, boiling decocts 40min, and extracting solution crosses 150 mesh screens, goes to receiver, collects extracting solution, steam pressure 0- 0.25MPa。
3, concentration operation is as follows：
Single-action concentrates：Single-effect concentrator, vacuum valve and cooling tower are opened, control steam pressure is 0-0.10MPa, and temperature is 60-85 DEG C, vacuum degree is -0.03MPa~-0.09MPa；Respectively to gained plantain seed maceration extract in step 3, rheum officinale percolate into Row concentration, it is 1.06-1.12 to be concentrated into relative density（80℃）Thick paste；
Economic benefits and social benefits concentrate：Dual-effect concentrator, vacuum valve and cooling tower are opened, control steam pressure is 0-0.10MPa, temperature I 70-90 DEG C of effect, II 65-85 DEG C of effect, vacuum degree is I effect -0.03MPa~-0.06MPa, II imitates -0.05 MPa~-0.08MPa； Gained extracting solution in step 3 is concentrated, it is 1.08 to be concentrated into relative density（80℃）When with above-mentioned single-action concentration gained it is thick Cream mixing continues to concentrate, and it is 1.06-1.12 to be concentrated into relative density（80℃）, obtain eight positive medicinal extract.
4, spray-drying operation is as follows：
To 50kg dextrin is added in eight positive medicinal extract of concentration gained in step 4, medicinal liquid agitating is uniform, is heated to 50-70 DEG C, into wind-warm syndrome Degree is 180-205 DEG C, and leaving air temp is 85-105 DEG C, and material revolution speed is 6-13r/min, and tower pressure interior force is negative pressure, spray drying, Powdered extract moisture≤4%.

Claims (6)

1. a kind of production method of eight positive extract powders of talcum, caulis clematidis armandii compounding, it is characterised in that：The pre-treating technology of raw material For：Dianthus superbus, pivots are stored, rush cleans, cutting, rheum officinale is cleaned, is crushed, crushes and obtains rheum officinale coarse powder, by caulis clematidis armandii, Cape jasmine Son, Radix Glycyrrhizae clean, be crushed, take medicinal material talcum, remove impurity, cleaned after talcum；Dipping, diacolation, extraction process are：It will Plantain seed adds alcohol dipping to extract, and obtains plantain seed maceration extract；Rheum officinale coarse powder is added into ethanol wet, is impregnated, seepage pressure effects obtain Rheum officinale percolate；By the dianthus superbus, pivots storage of pre-treatment, talcum, caulis clematidis armandii, cape jasmine, Radix Glycyrrhizae, rush mixed ingredients, add water three Secondary decoction extraction, obtains extracting solution；Plantain seed maceration extract, rheum officinale percolate single-action are concentrated to give thick paste, by extracting solution economic benefits and social benefits It is mixed with gained thick paste after concentration and is concentrated to give eight positive medicinal extract, dextrin heating is added, spray drying obtains described eight positive medicinal extract Powder.
2. the production method of eight positive extract powders of a kind of talcum according to claim 1, caulis clematidis armandii compounding, feature exist In the pre-treating technology operation of raw material is as follows：
（1）Dianthus superbus, pivots storage, rush pre-treatment：
It takes medicinal material dianthus superbus, pivot to store, rush, removes impurity, dianthus superbus, the pivot after cleaning are stored, rush is respectively put into turnover and holds In device, it is transferred to cutting area, with Linear reciprocating type medicine slicing machine cutting, length≤8cm after cutting；
（2）Rheum officinale coarse powder pre-treatment：
Medicinal material rheum officinale is taken, impurity is removed, the rheum officinale after cleaning is put into transfer container, fracture area is transferred to, is with mesh size The super power crusher of 1cm is broken, then the pulverizer sieved with 10 mesh crushes；
（3）Talcum pre-treatment：
Medicinal material talcum is taken, impurity is removed, the talcum after cleaning is put into transfer container；
（4）Caulis clematidis armandii, cape jasmine, Radix Glycyrrhizae pre-treatment：
Medicinal material caulis clematidis armandii, cape jasmine, Radix Glycyrrhizae are taken, impurity is removed, caulis clematidis armandii, cape jasmine, the Radix Glycyrrhizae after cleaning, which are respectively put into turnover, to be held In device, it is transferred to fracture area, the super power crusher for being 3cm with mesh size is crushed.
3. the production method of eight positive extract powders of a kind of talcum according to claim 1, caulis clematidis armandii compounding, feature exist In dipping, diacolation, extraction process operation are as follows：
Impregnation technology：Plantain seed (stir-fry) is put into extraction tank, 8 times of 25% alcohol dippings of amount are added for 24 hours, collect plantain seed dipping Liquid；
Diacolation technique：The rheum officinale that gained is handled well in step 2 is put into percolate pot, it is wet that 2 times of amount 50% ethyl alcohol progress are first added Profit after impregnating for 24 hours, adds 9 times of 50% ethyl alcohol of amount and carries out diacolation, collect rheum officinale percolate, diacolation speed is 3-5ml/kg.min；
Extraction process：After the dianthus superbus, pivots storage handled well in step 2, talcum, caulis clematidis armandii, cape jasmine, Radix Glycyrrhizae, rush are mixed It is divided into four parts, puts into multi-function extractor, per tank, 12 times of amount drinking water, heating are added in extraction for the first time, and boiling decocts 1.5h, Extracting solution crosses 150 mesh screens, goes to receiver；10 times of amount drinking water are added in second of extraction, and boiling decocts 1h, extracting solution mistake 150 mesh screens, go to receiver；8 times of amount drinking water are added in third time extraction, and boiling decocts 40min, and extracting solution crosses 150 mesh sieve Net goes to receiver, collects extracting solution, steam pressure 0-0.25MPa.
4. the production method of eight positive extract powders of a kind of talcum according to claim 1, caulis clematidis armandii compounding, feature exist In concentration operation is as follows：
Single-action concentrates：Single-effect concentrator, vacuum valve and cooling tower are opened, control steam pressure is 0-0.10MPa, and temperature is 60-85 DEG C, vacuum degree is -0.03MPa~-0.09MPa；Respectively to gained plantain seed maceration extract in step 3, rheum officinale percolate into Row concentration is concentrated into the thick paste that relative density is 1.06-1.12；
Economic benefits and social benefits concentrate：Dual-effect concentrator, vacuum valve and cooling tower are opened, control steam pressure is 0-0.10MPa, temperature I 70-90 DEG C of effect, II 65-85 DEG C of effect, vacuum degree is I effect -0.03MPa~-0.06MPa, II imitates -0.05 MPa~-0.08MPa； Gained extracting solution in step 3 is concentrated, thick paste obtained by being concentrated with single-action is concentrated into when relative density is 1.08 and mixes continuation Concentration, it is 1.06-1.12 to be concentrated into relative density, obtains eight positive medicinal extract.
5. the production method of eight positive extract powders of a kind of talcum according to claim 1, caulis clematidis armandii compounding, feature exist In spray-drying operation is as follows：
To dextrin is added in eight positive medicinal extract of concentration gained in step 4, medicinal liquid agitating is uniform, is heated to 50-70 DEG C, and inlet air temperature is 180-205 DEG C, leaving air temp is 85-105 DEG C, and material revolution speed is 6-13r/min, and tower pressure interior force is negative pressure, is spray-dried, dry Medicinal extract moisture≤4%.
6. a kind of production method of eight positive extract powders of talcum, caulis clematidis armandii compounding according to claim 1,2,3,4,5, It is characterized in that, wherein dianthus superbus, pivots storage, rheum officinale, talcum, caulis clematidis armandii, cape jasmine, Radix Glycyrrhizae, plantain seed (stir-fry), rush, dextrin matter Amount is than being 2:2:2:2:2:2:2:2:1:0.4.
CN201810198423.7A 2018-03-12 2018-03-12 A kind of talcum, caulis clematidis armandii compounding eight positive extract powders production method Pending CN108324806A (en)

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Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1634260A (en) * 2004-10-28 2005-07-06 重庆希尔安药业有限公司 Novel method for preparing 'Bazheng Tablet'
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Publication number Priority date Publication date Assignee Title
US20060121129A1 (en) * 2004-04-27 2006-06-08 Harvey Bryce M Dietary supplement
CN1634260A (en) * 2004-10-28 2005-07-06 重庆希尔安药业有限公司 Novel method for preparing 'Bazheng Tablet'

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Application publication date: 20180727