CN106726573A - The Traditional Chinese medicine decocting device and method of a kind of scale - Google Patents

Abstract

The invention is a large-scale traditional Chinese medicine decoction device and method. The composition of the device includes: steam generator, condensate tank, automatic feeder, decoction kettle, concentrator, injection and water tank; wherein, the steam outlet of the steam generator is connected with the jacketed steam inlet of the decoction kettle, concentrated The jacket steam inlet of the device is connected; the top of the condensate tank is respectively connected with the jacket condensate outlet of the decoction kettle and the jacket condensate outlet of the concentrator; the outlet of the condensate tank is connected with the return port of the steam generator; The feeding mechanism of the feeder is located directly above the decoction kettle, and the discharge port of the decoction kettle is connected with the feed port of the concentrator; the top secondary steam outlet of the decoction kettle and the top secondary steam outlet of the concentrator are respectively It is connected with the suction port of the jet pump, and the jet port of the jet pump is connected with the water tank; the bottom of the concentrator is connected with the automatic packaging line. The invention is suitable for large-scale decoction production.

Description

A large-scale traditional Chinese medicine decoction device and method

Technical field:

The invention belongs to the technical field of traditional Chinese medicine processing, and in particular relates to a large-scale traditional Chinese medicine decoction device and method.

Background technique:

The preparation of traditional Chinese medicine decoction has been using the traditional manual method, which is time-consuming and labor-intensive. It is prone to mold and deterioration after long-term storage, and there are problems such as the quality and hygiene of the decoction. The advent of the traditional Chinese medicine decoction machine has not only greatly improved the environment of manual decoction, but also increased the content of active ingredients in the obtained decoction, reduced the oxidation failure of active ingredients, and used a packaging form with a high pass rate of hygienic testing indicators. ——Bag decoction, which is easy to carry and easy to take, bringing convenience to the majority of patients.

At present, the technology of traditional Chinese medicine decoction machine has been greatly developed, but there are still many problems. First of all, the device and process of the current traditional Chinese medicine decoction machine are too simple, so most of them are small-scale and home-use traditional Chinese medicine decoction machines. There are few large-scale industrial production devices; secondly, there are problems such as uneven heating in traditional Chinese medicine decoction machines, easy to paste pots, medicinal residues that cannot be processed automatically, and the secondary steam produced by decoction smells bad and pollutes the air. In order to promote the development and application of traditional Chinese medicine decoction machine technology, some new patented inventions have emerged recently to solve some of the problems, but they still cannot be completely solved. Within the scope of the applicant's search, the invention patent titled "A High-Efficiency Hermetic Steam Decoction Machine" (application number 201510082642.5) proposed a method of steam heating and recovery of residual steam. The temperature of the decoction machine is more uniform and less There will be problems such as sticky pots, and the residual steam in the heating chamber can be recycled to the steam generator for recycling, but the medicinal residues of this invention cannot be processed automatically, the operation is complicated, and the secondary steam generated by the decoction cannot be processed, which has an impact on the environment larger. The invention patent (application number 201510924718.4) named "Automatic Chinese Medicine Decoction Pharmaceutical Device" proposes a set of multi-tank combined device including soaking tank, medicine feeding tank and extraction tank, which realizes batch and stage feeding, It meets the requirements of decocting first and then removing, and can realize large-scale production. However, the device does not have an automatic treatment method for medicinal residues, and manual unloading is required. When the medicinal liquid enters the concentration tank, a vacuum pump is required for vacuum operation, and the secondary steam condenser is a tube. Type heat exchanger, a large investment, poor economy.

In summary, in the prior art, there is not yet a device and method for decocting traditional Chinese medicine that is the same as the present invention. The method of the present invention is positioned at the large-scale decoction device and process for traditional Chinese medicine used in the medical industry, and has the following advantages: low cost, heating Uniform, not easy to paste pot, liquid medicine and medicinal residue can be separated automatically, liquid medicine can enter the concentration tank by itself, secondary steam condensation recovery does not pollute the environment, and vacuum operation is realized without a vacuum pump.

Invention content:

The object of the present invention is to provide a large-scale device and method for decocting traditional Chinese medicines to solve the problems existing in the decocting of traditional Chinese medicines. The device adopts the integrated design of the decoction kettle and the concentration tank, which can be operated continuously without manual unloading, and the operation of the concentration tank will not be affected when the slag is unloaded; the vacuum system is realized by a jet pump, and the secondary steam condensation is realized at the same time; the decoction kettle The inner bottom centrifugal device can realize the separation of residual liquid and medicine residue. The invention can effectively solve the problems of uneven temperature distribution of the decoction machine, inability to automatically separate liquid medicine and medicine dregs, environmental pollution by secondary steam, and high device investment cost.

Concrete technical scheme of the present invention is:

A large-scale traditional Chinese medicine decoction device, the composition of the device includes: a steam generator, a condensed water tank, an automatic feeder, a decoction kettle, a concentrator, a jet pump and a water tank; wherein, the steam outlets of the steam generator are respectively It is connected with the jacket steam inlet of the decoction kettle and the jacket steam inlet of the concentrator; the top of the condensate tank is respectively connected with the jacket condensate outlet of the decoction kettle and the jacket condensate outlet of the concentrator; The outlet is connected to the return port of the steam generator; the feeding mechanism of the automatic feeder is located directly above the decoction kettle, and the discharge port of the decoction kettle is connected to the feed port of the concentrator; the secondary steam on the top of the decoction kettle The outlet and the secondary steam outlet on the top of the concentrator are respectively connected to the suction port of the jet pump, and the jet port of the jet pump is connected to the water tank; the bottom of the concentrator is connected to the automatic packaging line.

The composition of the decoction kettle device includes: a medicine decoction kettle body, an upper transmission shaft, a traditional Chinese medicine basket, a lower transmission shaft, a driving motor and a discharge valve; wherein, an openable upper head is arranged on the top of the medicine decoction kettle body , the top of the upper transmission shaft is connected with the automatic feeder, and its bottom is connected with the traditional Chinese medicine basket; The motor is connected; the bottom of the decoction kettle body is provided with a discharge port, and the pipeline outside the discharge port is provided with a discharge valve; connected; the volume of the decoction kettle is 1-10m ³ ;

The composition of the concentrator device includes: a concentrator kettle body and a demister; wherein the demister is located below the outlet of the head on the concentrator kettle body and above the liquid level in the concentrator; the concentrator kettle body is provided with Steam jacket, jacket condensate outlet is connected with the top of condensate tank.

The described large-scale method for decocting traditional Chinese medicine comprises the following steps:

Wash the raw materials of Chinese herbal medicine, put them into the Chinese medicine basket, and send them into the decoction kettle. The upper transmission shaft is separated from the Chinese medicine basket, and the Chinese medicine basket is fixed by the lower transmission shaft. The soaking time is 15-30 minutes, and then decocted at 70-100°C Boil for 30-40 minutes, then drive the motor to centrifuge the medicinal liquid and medicinal residues, and discharge the medicinal liquid into the concentrator tank through the discharge valve. The vacuum degree is 20-80KPa, and the temperature is 60-90°C. Concentrate for 15-20 Minutes, and finally sent to the automatic packaging line filling package.

The Chinese herbal medicine is preferably Jugeng Decoction, Siwu Decoction or Bazhen Yimu Fang.

Substantive features of the present invention are:

1. The decoction kettle and the concentrating tank are continuous and can be operated continuously without manual unloading, and the operation of the concentrating tank will not be affected during unloading, which is not available in other steam heating decoction concentrating devices. 2. The vacuum system is realized by a jet pump, which realizes secondary steam condensation at the same time. The jet pump has no rotating parts and does not need electric drive. It is easier to maintain and save energy than a vacuum pump. This point has not been used in other decoction devices. 3. The centrifugal device at the bottom of the decoction kettle can realize the separation of residual liquid and medicinal residues, which has not been seen in large-scale device patents. 4. The device has a high degree of automation, simple process flow, easy realization of large-scale production, and low investment.

The advantages and beneficial effects of the present invention are: compared with the prior art, the present invention provides a large-scale traditional Chinese medicine decoction device and method, several sets of decoction kettles and concentrators can be used in parallel to realize large-scale production, It is especially suitable for use in large medical institutions; steam heating ensures that the medicinal liquid is heated evenly and stably during the decoction process, and it is not easy to paste the pot, and the active ingredients are not easy to lose; the feeding and slag discharge can be completed automatically, and the medicinal liquid and medicinal residue can be centrifugally separated. The loss of medicinal liquid is avoided; the jet pump is used to realize secondary steam condensation and vacuum operation, which saves the condenser and vacuum pump, and saves investment costs. At the same time, vacuum operation can effectively reduce the temperature of decoction and concentration, especially suitable for heat-sensitive Chinese herbal medicines; The condensed water of the secondary steam can be recycled to make medicine, and the condensed water of the heated steam can be returned to the steam generator for recycling, so as to realize zero emission and waste heat recovery, save energy and reduce consumption, and protect the environment.

Taking the production of bellflower soup with an output of 5 tons per day as an example, the extraction of active ingredients by this process is about twice that of the traditional process, and it can save 7 to 10 tons of water per day and about 15% of electricity consumption. Due to the high degree of automation, workers About 5-8 people can be reduced, and the one-time investment of the device can save about 10-20% compared with the existing process, especially when the production scale is larger, the investment will be less, so this process is suitable for large-scale decoction production.

Description of drawings:

Fig. 1 is a kind of process equipment structure schematic diagram of the present invention, wherein 1 is steam generator, 2 is condensed water tank, 3 is automatic feeding mechanism, 4 is decoction pot, 5 is concentrator, 6 is jet pump, 7 for the sink.

Fig. 2 is a structural schematic diagram of 4 decocting kettle devices, 41 is a decocting medicine kettle body, 42 is an upper transmission shaft, 43 is a Chinese medicine basket, 44 is a lower transmission shaft, 45 is a driving motor, and 46 is a discharge valve.

Fig. 3 is the structural representation of 5 concentrator devices, 51 is the still body of the concentrator, 52 is the demister,

detailed description

The present invention will be described in further detail below in conjunction with accompanying drawing 1.

The composition of decoction device of the present invention comprises: steam generator 1, condensed water tank 2, automatic feeder 3, decoction pot 4, concentrator 5, injection 6 and water tank 7; Wherein, the steam outlet of steam generator 1 They are respectively connected to the jacket steam inlet of the decoction kettle 4 and the jacket steam inlet of the concentrator 5; connected; the outlet of the condensed water tank 2 is connected with the water return port of the steam generator 1; the feeding mechanism of the automatic feeder 3 is located directly above the decoction kettle 4, and the discharge port of the decoction kettle 4 is connected with the inlet of the concentrator 5 The material port is connected; the top secondary steam outlet of the decoction kettle 4 and the top secondary steam outlet of the concentrator 5 are respectively connected with the suction port of the jet pump 6, and the jet port of the jet pump 6 is connected with the water tank 7; the bottom of the concentrator 5 Connected with automatic packing line.

As shown in Figure 2, the composition of decoction kettle 4 device comprises: decoction kettle body 41, upper transmission shaft 42, Chinese medicine basket 43, lower transmission shaft 44, drive motor 45 and discharge valve 46; Wherein, decoction kettle body The top of 41 is provided with an openable upper head, and the top of the upper transmission shaft 42 is connected with the automatic feeder 3, (the Chinese medicinal liquid is sent into the kettle by the transmission shaft 42, and the transmission shaft also transmits the rotating power ) its bottom end links to each other with the Chinese medicine basket 43, provides power by the automatic feeder 3, and the upper transmission shaft 42 can send the Chinese medicine basket 43 in the decocting medicine kettle, and can break away automatically; The bottom of the Chinese medicine basket 43 is connected with the lower transmission shaft 44 The top of the decoction kettle body 41 is connected, and the lower transmission shaft 44 passes through the bottom of the decoction kettle body 41 and is connected with the drive motor 45; the bottom of the decoction kettle body 41 is provided with a discharge port, and a discharge valve 46 is provided on the pipeline outside the discharge port; A steam jacket is arranged outside the body of the decoction kettle 41 , and the outlet of the condensed water of the jacket is connected to the top of the condensed water tank 2 . The volume of the decoction kettle 41 is 1-10m ³ ;

As shown in Figure 3, the composition of described concentrator 5 device comprises: concentrator kettle body 51, demister 52; above the internal liquid level; the body of the concentrator kettle is provided with a steam jacket, and the condensed water outlet of the jacket is connected to the top of the condensed water tank 2 .

The Chinese herbal medicines are loaded into the Chinese medicine basket 43 and sent into the decoction kettle body 41 by the upper transmission shaft 42 through the automatic feeding mechanism 3. The upper transmission shaft 42 is separated from the Chinese medicine basket 43, and the Chinese medicine basket 43 is fixed by the lower transmission shaft and driven by the driving motor. 45 realizes the centrifugal separation of medicinal liquid and medicinal residues. The decoction kettle body 41 is connected with the concentrated kettle body 51 by a direct connection pipeline. The medicinal solution can be discharged into the concentrator kettle body 51 through the discharge valve 46, and then sent into the Automatic packing line filling packs. The heating steam generated by the steam generator 1 is respectively connected to the jacket of the decoction kettle body 41 and the concentrator kettle body 51 through pipelines, and the condensed water after heat release flows into the condensed water tank 2 through the pipelines, and finally the condensed water is sent back to the steam generator 1 for recycling. The secondary steam generated in the decoction kettle body 41 and the concentrator kettle body 51 enters the jet pump 6 through the pipeline from the top secondary steam outlet of the respective kettle body, and is discharged into the water tank 7 by the pipeline after condensation.

The specific implementation of the present invention will be described in detail below in conjunction with the examples. For example, if the amount of traditional Chinese medicine is 1 ton/day, the diameter of the decoction kettle is 1500mm and the height is 2000mm; the diameter of the concentration kettle is 800mm and the height is 1500mm.

Embodiment one:

Ordinary decoction machine process of bellflower soup: Take 17kg bellflower and 33kg licorice, remove impurities, wash, put into the decoction machine, set the soaking time for 30 minutes, decoct for 35 minutes, and take out the samples after decoction is completed.

Vacuum low-temperature decoction process of orange terrier soup:

Take 17kg of bellflower and 33kg of licorice, remove impurities, wash them, put them into a traditional Chinese medicine basket, set the soaking time for 30 minutes, decoct for 35 minutes, and concentrate for 20 minutes. The vacuum degree during decoction and concentration is 50KPa, and the temperature is 80°C. Sampling after discharge. The condensed water of the secondary steam can be recycled to make medicine, saving 30% of water

Determination of active ingredients in extracts: Liquiritin and glycyrrhizinamide are the main active ingredients in Jugeng Decoction for promoting lung, relieving cough, clearing away heat and detoxifying. Therefore, the present embodiment adopts these two kinds of ingredients as the quality control standard of Jugeng Decoction. Adopt HPLC method to measure the content of glycyrrhizic acid and liquiritin in decoction, chromatographic column condition: (4.6mm * 250mm, 5 μ m): acetonitrile is mobile phase A; 0.05% phosphoric acid solution is mobile phase B; carry out gradient elution ; Detection wavelength: 327nm; Column temperature: 25°C; Injection volume: 20 μL.

Table 1 is a comparison of the content determination results of the main components liquiritin and glycyrrhizin amine in the decoction prepared by two different decoction processes of Jugeng decoction

Table 1 Comparison of the main components in the decoction prepared by two different decoction processes of Jugeng Decoction

It can be seen from Table 1 that the content of active ingredients in the decoction prepared by the vacuum low-temperature decoction process is higher than that of the ordinary decoction machine process, indicating that the vacuum low-temperature decoction process is superior to the ordinary decoction machine process in terms of the quality of the decoction .

Embodiment two:

Siwu Decoction Ordinary Decoction Machine Process: According to the Siwu Decoction prescription, take a total of 50kg of rehmannia glutinosa, angelica, white peony root and Chuanxiong, remove impurities, wash, put into the decoction machine, set the temperature at 100°C, 1 atmosphere, Boil for 45 minutes, start the program, fill it after completion, set aside half, and evaporate the other half into powder.

Vacuum low-temperature decoction process of Siwu Decoction: Take a total of 50kg of rehmannia glutinosa, angelica, white peony root and Chuanxiong according to the Siwu Decoction prescription, remove impurities, wash, put into a traditional Chinese medicine basket, set the soaking time for 20 minutes, and decoct for 40 Minutes, concentrated for 15 minutes, vacuum degree 80KPa, temperature 60°C when decocting and concentrating, filling after concentrating, half for standby, the other half evaporated to powder. The condensed water of the secondary steam can be recycled to make medicine, saving 20% of water

Determination of extracts: Weigh the evaporated powder under the two process methods;

Determination of active ingredients in decoction: The main active ingredients in Siwu decoction are ferulic acid, paeoniflorin and ligustrazine. The contents of ferulic acid, paeoniflorin and ligustrazine in Siwu decoction were detected by HPLC method. The content of glycyrrhizic acid and liquiritin in the decoction was determined by HPLC method, and the chromatographic column conditions are shown in Table 2.

Table 3 is a comparison of the extracts of Siwu Decoction by two processes. It can be seen from the table that under the same conditions, the extract quality of Siwu Decoction prepared by the vacuum low-temperature decoction process is much higher than that by the ordinary decoction machine process, which shows that the new process is more reasonable and efficient.

Table 2 Column conditions

Table 3 Comparison of extracts of Siwu Decoction by two processing methods

Table 4 is the comparison of the extraction rates of ferulic acid, paeoniflorin and ligustrazine in Siwu decoction by two processes. As can be seen from the table, ferulic acid and paeoniflorin are The extraction rate of Ligustrazine and Ligustrazine is higher, indicating that the new process can significantly increase the content of active ingredients in the decoction, with good clinical curative effect, high efficiency and energy saving.

Table 4 Comparison of the extraction rate of active ingredients in Siwu Decoction by two processes (%/dose)

Embodiment three:

Bazhen Yimu Recipe Ordinary Decoction Machine Process Method: Take motherwort, Codonopsis pilosula, Atractylodes macrocephala, Huquan, licorice, rehmannia glutinosa, angelica, white peony root, and Chuan peony in total 50kg according to the Bazhen Yimu prescription, remove impurities, wash, pack Put it into the decoction machine, soak for 30 minutes, then set the temperature at 120°C and 2 atmospheres, decoct for 50 minutes, and fill it after completion.

Vacuum low-temperature decoction process of Bazhen Yimu Recipe: Take motherwort, Codonopsis pilosula, Atractylodes macrocephala, Huquan, licorice, rehmannia glutinosa, angelica, white peony root, and Chuan peony in total 50kg according to Bazhen yimu prescription, remove impurities, wash, pack Put it into the Chinese medicine basket, turn on the automatic control system, set the soaking time for 20 minutes, decoct for 45 minutes, concentrate for 15 minutes, vacuum degree 70KPa, temperature 70°C, and fill after concentration. The condensed water of the secondary steam can be recycled to make medicine, saving 28% of water.

Determination of active ingredients in decoction: the monarch drug of Bazhen Yimu Formula is Motherwort, and stachydrine is an important quality control indicator of Motherwort. Determination of its content can be used as an important indicator for evaluating the quality of Bazhen Yimu Formula. Adopt HPLC method to measure the content of stachydrine in decoction, chromatographic column condition: (4.6mm * 250mm, 5 μ m): acetonitrile is mobile phase A; 20% water is mobile phase B; Column temperature: 40 ℃; The sample volume is 10 μL.

Table 5 is a comparison of the extraction rate of stachydrine in Bazhen Yimu Fang by two processes. It can be seen from the table that the extraction rate of stachydrine in the new process is higher, indicating that the new process has better extraction and protection of active ingredients , avoiding the damage to the active ingredients of the drug at high temperature, and improving the clinical efficacy.

Table 5 Comparison of the extraction rate of stachydrine in Bazhen Yimu Fang by two processes (%/dose)

Matters not covered in the present invention are known technologies.

Claims (3)

1. A large-scale Chinese medicine decoction device is characterized in that the device comprises: a steam generator, a condensed water tank, an automatic feeder, a decoction kettle, a concentrator, a jet pump and a water tank; wherein, the steam generator The steam outlet of the device is respectively connected with the jacket steam inlet of the decoction kettle and the jacket steam inlet of the concentrator; the top of the condensate tank is respectively connected with the jacket condensate outlet of the decoction kettle and the jacket condensate outlet of the concentrator ;The outlet of the condensate tank is connected with the return port of the steam generator; the feeding mechanism of the automatic feeder is located directly above the decoction kettle, and the discharge port of the decoction kettle is connected with the feed port of the concentrator; The top secondary steam outlet of the concentrator and the top secondary steam outlet of the concentrator are respectively connected to the suction port of the jet pump, and the jet port of the jet pump is connected to the water tank; the bottom of the concentrator is connected to the automatic packaging line; The composition of the decoction kettle device includes: a medicine decoction kettle body, an upper transmission shaft, a traditional Chinese medicine basket, a lower transmission shaft, a driving motor and a discharge valve; wherein, an openable upper head is arranged on the top of the medicine decoction kettle body , the top of the upper transmission shaft is connected with the automatic feeder, and its bottom is connected with the traditional Chinese medicine basket; The motor is connected; the bottom of the decoction kettle body is provided with a discharge port, and the pipeline outside the discharge port is provided with a discharge valve; connected; the volume of the decoction kettle is 1-10m ³ ; The composition of the concentrator device includes: a concentrator kettle body and a demister; wherein the demister is located below the outlet of the head on the concentrator kettle body and above the liquid level in the concentrator; the concentrator kettle body is provided with Steam jacket, jacket condensate outlet is connected with the top of condensate tank. 2. the method for the decoction of traditional Chinese medicine of scale as claimed in claim 1 is characterized in that comprising the following steps: Wash the raw materials of Chinese herbal medicine, put them into the Chinese medicine basket, and send them into the decoction kettle. The upper transmission shaft is separated from the Chinese medicine basket, and the Chinese medicine basket is fixed by the lower transmission shaft. The soaking time is 15-30 minutes, and then decocted at 70-100°C Boil for 30-40 minutes, then drive the motor to centrifuge the medicinal liquid and medicinal residues, and discharge the medicinal liquid into the concentrator tank through the discharge valve. The vacuum degree is 20-80KPa, and the temperature is 60-90°C. Concentrate for 15-20 Minutes, and finally sent to the automatic packaging line filling package. 3. The method for large-scale decoction of Chinese medicine as claimed in claim 2, characterized in that said Chinese herbal medicine is preferably Jugeng Decoction, Siwu Decoction or Bazhen Yimu Fang.