CN115322845B - Antibacterial blood stain removing composition and preparation method and application thereof - Google Patents

Antibacterial blood stain removing composition and preparation method and application thereof Download PDF

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Publication number
CN115322845B
CN115322845B CN202210769799.5A CN202210769799A CN115322845B CN 115322845 B CN115322845 B CN 115322845B CN 202210769799 A CN202210769799 A CN 202210769799A CN 115322845 B CN115322845 B CN 115322845B
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extract
parts
composition
antibacterial
underwear
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CN115322845A (en
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刘少峰
姜皓泉
张岩
齐钊
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Huiscom Biotechnology Shenzhen Co ltd
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Huiscom Biotechnology Shenzhen Co ltd
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    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
    • C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
    • C11D3/48—Medical, disinfecting agents, disinfecting, antibacterial, germicidal or antimicrobial compositions
    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
    • C11D1/00—Detergent compositions based essentially on surface-active compounds; Use of these compounds as a detergent
    • C11D1/02—Anionic compounds
    • C11D1/12—Sulfonic acids or sulfuric acid esters; Salts thereof
    • C11D1/29—Sulfates of polyoxyalkylene ethers
    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
    • C11D1/00—Detergent compositions based essentially on surface-active compounds; Use of these compounds as a detergent
    • C11D1/66—Non-ionic compounds
    • C11D1/662—Carbohydrates or derivatives
    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
    • C11D1/00—Detergent compositions based essentially on surface-active compounds; Use of these compounds as a detergent
    • C11D1/66—Non-ionic compounds
    • C11D1/72—Ethers of polyoxyalkylene glycols
    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
    • C11D1/00—Detergent compositions based essentially on surface-active compounds; Use of these compounds as a detergent
    • C11D1/66—Non-ionic compounds
    • C11D1/825—Mixtures of compounds all of which are non-ionic
    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
    • C11D1/00—Detergent compositions based essentially on surface-active compounds; Use of these compounds as a detergent
    • C11D1/66—Non-ionic compounds
    • C11D1/83—Mixtures of non-ionic with anionic compounds
    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
    • C11D1/00—Detergent compositions based essentially on surface-active compounds; Use of these compounds as a detergent
    • C11D1/88—Ampholytes; Electroneutral compounds
    • C11D1/90—Betaines
    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
    • C11D1/00—Detergent compositions based essentially on surface-active compounds; Use of these compounds as a detergent
    • C11D1/88—Ampholytes; Electroneutral compounds
    • C11D1/94—Mixtures with anionic, cationic or non-ionic compounds
    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
    • C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
    • C11D3/16—Organic compounds
    • C11D3/20—Organic compounds containing oxygen
    • C11D3/2003—Alcohols; Phenols
    • C11D3/2065—Polyhydric alcohols
    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
    • C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
    • C11D3/16—Organic compounds
    • C11D3/20—Organic compounds containing oxygen
    • C11D3/2075—Carboxylic acids-salts thereof
    • C11D3/2086—Hydroxy carboxylic acids-salts thereof
    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
    • C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
    • C11D3/16—Organic compounds
    • C11D3/38—Products with no well-defined composition, e.g. natural products
    • C11D3/382—Vegetable products, e.g. soya meal, wood flour, sawdust
    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
    • C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
    • C11D3/16—Organic compounds
    • C11D3/38—Products with no well-defined composition, e.g. natural products
    • C11D3/386—Preparations containing enzymes, e.g. protease or amylase
    • C11D3/38618—Protease or amylase in liquid compositions only
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

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  • Oil, Petroleum & Natural Gas (AREA)
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  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Detergent Compositions (AREA)

Abstract

The invention discloses a composition for inhibiting bacteria and removing blood stains, and a preparation method and application thereof. The composition comprises the following components in parts by weight: 5 to 11 parts of stemona extract, 5 to 11 parts of curcuma zedoary extract, 9 to 16 parts of sweet wormwood extract, 3 to 7 parts of gallnut extract, 6 to 11 parts of duckweed extract, 12 to 16 parts of soapberry extract and 0.5 to 2 parts of plant protease. According to the invention, the stemona root extract, the curcuma zedoary extract, the sweet wormwood extract, the gallnut extract and the duckweed extract are combined according to a certain proportion, and the combination of the stemona root extract, the curcuma zedoary extract, the sweet wormwood extract and the duckweed extract has a rapid antibacterial effect on three female frequently-infected fungi such as escherichia coli, candida albicans and staphylococcus aureus, and the antibacterial rate can reach more than 80% in 2 minutes; meanwhile, the soapberry extract and the plant protease are selected to match a certain proportion, so that the antibacterial effect is not affected, blood stains can be remarkably removed, and the soapberry extract and the plant protease can be further used for preparing female underwear washing products.

Description

Antibacterial blood stain removing composition and preparation method and application thereof
Technical Field
The invention relates to the technical field of sanitary products, in particular to a composition for inhibiting bacteria and removing blood stains, a preparation method and application thereof.
Background
As the female physiological structure is special, if the underwear is not cleaned in place, bacteria are easily propagated in a warm and humid environment. So that the demand of women's underwear special washing products is great at present. However, many of the currently available liquid laundry detergents contain irritating ingredients and are sensitive to skin and thus require the provision of safe, non-irritating underwear washing solutions. Chinese patent CN104893847A discloses a special liquid laundry detergent for women's underpants, which has no rapid antibacterial effect on three women's frequently infected fungi such as escherichia coli, candida albicans and staphylococcus aureus although the antibacterial function is realized by utilizing a traditional Chinese medicine antibacterial formula.
In daily life, especially during menstrual period of women in each month, the underwear is inevitably stained with blood; the bloodstains are difficult to remove, fresh bloodstains can be dissolved in water, and old bloodstains are oxidized due to iron in the bloodstains, complex with protein and solidify, so that the bloodstains are difficult to remove by simply using a chemical detergent after being stained on fabrics, and trace residues remain even after the bloodstains are washed, so that the attractiveness and subsequent use of the fabrics are very affected. Currently, enzyme reagents are usually added into detergents to decompose and remove fats and proteins in the blood stains so as to achieve the effect of removing the blood stains on fabrics, however, currently adopted enzyme reagents are mainly enzymes produced by using gene functional enzyme strains, for example, chinese patent No. 101514306A discloses a fabric stain pretreatment agent containing stable biological enzyme complex and low-activity substances, protease of the enzyme reagents needs to be matched with a plurality of chemicals, such as surfactants, stabilizers and the like so as to achieve a certain blood stain removing function, and the protease reagents have a certain removing effect on fresh blood stains, but have a poor blood stain removing effect on long-term residues. In summary, there is an urgent need to provide a product which has a fast antibacterial effect on escherichia coli, candida albicans and staphylococcus aureus, can effectively remove old blood stains remained on clothes, is safe to human body, and has no irritation.
Disclosure of Invention
The invention aims to overcome the defects and shortcomings in the prior art and provide a composition with the functions of inhibiting bacteria and removing blood stains.
The second object of the invention is to provide a preparation method of the composition with the functions of bacteriostasis and blood stain removal.
A third object of the present invention is to provide the use of the composition with antibacterial and blood stain removing effects.
The above object of the present invention is achieved by the following technical solutions:
the composition with the antibacterial and blood stain removing effects comprises the following components in parts by weight: 5 to 11 parts of stemona extract, 5 to 11 parts of curcuma zedoary extract, 9 to 16 parts of sweet wormwood extract, 3 to 7 parts of gallnut extract, 6 to 11 parts of duckweed extract, 12 to 16 parts of soapberry extract and 0.5 to 2 parts of plant protease. The plant extracts are water extracts with crude drug content of 50%.
In the composition, stemonae radix extract, curcumae rhizoma extract, herba Artemisiae Annuae extract, galla chinensis extract, and herba Spirodelae extract are used as antibacterial components, and herba Saponin extract and plant protease are used as blood stain removing components. According to the invention, the combination has a rapid antibacterial effect on three female frequently-infected fungi such as escherichia coli, candida albicans and staphylococcus aureus by combining and using the specific components and the ratio of radix stemonae extract, curcuma zedoary extract, sweet wormwood extract, gallnut extract and duckweed extract, and the antibacterial rate of the combination on the escherichia coli, candida albicans and staphylococcus aureus exceeds 80% in 2 min; meanwhile, the soapberry extract and the plant protease in a certain proportion are matched, so that the antibacterial effect of the soapberry extract is not affected, the composition has a remarkable blood stain removing effect, and particularly has an excellent blood stain removing effect on old blood stains.
Preferably, the composition comprises the following components in parts by weight: 6-9 parts of stemona extract, 6-9 parts of curcuma zedoary extract, 12-15 parts of sweet wormwood extract, 4-6 parts of Chinese gall extract, 6-9 parts of duckweed extract, 14-16 parts of soapberry extract and 1-2 parts of plant protease.
Further preferably, the composition comprises the following components in parts by weight: 9 parts of stemona extract, 9 parts of curcuma zedoary extract, 15 parts of sweet wormwood extract, 6 parts of gallnut extract, 9 parts of duckweed extract, 16 parts of soapberry extract and 2 parts of plant protease.
Further, the antibacterial means to inhibit escherichia coli, candida albicans and staphylococcus aureus.
Further preferably, the plant protease is papain or bromelain.
Further preferably, the composition further comprises 0.2 to 0.6 parts of pomegranate seed oil. The pomegranate seed is an ideal skin nutritional agent, and the pomegranate seed oil can nourish skin, keep skin moist and improve skin elasticity; balancing the skin pH, thereby protecting the skin from free radicals; can quickly recover cracked and stimulated skin.
Further preferably, the composition further comprises 0.2 to 0.6 parts of Meinaria oil. The Meinaria oil generally has the effects of whitening skin, improving memory and the like. The Meinao fruit oil contains abundant vitamin C, can play a role in strong oxidation resistance after entering the body, is beneficial to improving skin pigmentation, and can make skin become more white after long-term use.
Further preferably, the composition further comprises 4 to 6 parts of selaginella extract. Herba Selaginellae is dried whole herb of herba Selaginellae Selaginella tamariscina (Beauv.) Spring or herba Selaginellae Selaginella pulvinata (HooK. Et Grev.) Maxim. Of Selaginellae family, and has effects of moistening skin and resisting aging.
The composition can play a role in protecting skin by matching with the pomegranate seed oil, the vine fruit oil and the selaginella extract.
Further preferably, the composition further comprises 2-4 parts of the mock strawberry extract, wherein more than 26% of uronic acid and more than 15% of protein fleshy polysaccharide are contained in the mock strawberry extract, so that the fabric can be softened, the water retention of the fabric can be improved, the softening effect of clothes can be improved, the fabric can keep good water absorption, and the soft mock strawberry extract is mild and does not hurt hands.
Further, the preparation method of the stemona extract, the curcuma zedoary extract, the sweet wormwood extract, the gallnut extract, the duckweed extract, the soapberry extract, the selaginella extract and the mock strawberry extract comprises the following steps:
100g of Chinese herbal medicine is taken, 1000mL of distilled water is added, soaking is carried out for 2 hours, heating and boiling are carried out, then the decoction is continued for 30 minutes, and the Chinese herbal medicine liquid is filtered. Continuously adding distilled water with equal volume into the residue, decocting for 1 time by the same method, filtering, and discarding residue. Mixing the decoctions, centrifuging, collecting supernatant, concentrating to crude drug concentration of 50%, sub-packaging, and autoclaving at 121deg.C for 15min to obtain plant extracts.
The composition has a rapid antibacterial effect on escherichia coli, candida albicans and staphylococcus aureus, has an excellent removal effect on old blood stains, is a natural plant component, is mild and non-irritating, and can be further used for preparing female underwear washing and protecting products. The invention also provides application of any one of the compositions in preparing a washing product for inhibiting bacteria and removing blood stains.
The invention also provides an antibacterial bloodstain-removing underwear washing liquid, which comprises the following components in percentage by weight: 5 to 10 percent of any one of the compositions, 15 to 20 percent of surfactant, 2 to 5 percent of stabilizer, 1 to 2 percent of water softener, 1 to 2 percent of humectant, 0.05 to 0.2 percent of pH regulator and the balance of purified water.
Preferably, the surfactant is any one or more of alkyl glycoside, cocamidopropyl betaine, fatty alcohol polyoxyethylene ether sodium sulfate, laurinol polyoxyethylene ether and isomeric alcohol polyoxyethylene ether.
Preferably, the stabilizer is sorbitol.
Preferably, the water softener is sodium citrate and/or sodium gluconate.
Preferably, the humectant is glycerin.
Preferably, the pH adjuster is citric acid.
The invention also provides a preparation method of the antibacterial bloodstain-removing underwear washing liquid, which comprises the following steps:
(1) Mixing enough water, sodium citrate, sodium gluconate, glycerol and fatty alcohol-polyoxyethylene ether sodium sulfate according to the proportion, and uniformly stirring.
(2) Adding alkyl glucoside, laurinol polyoxyethylene ether, isomeric alcohol polyoxyethylene ether and sorbitol according to a certain proportion, uniformly stirring.
(3) Adding cocamidopropyl betaine according to the proportion, and stirring uniformly.
(4) Adding the composition according to the proportion, and stirring uniformly.
(5) Adding citric acid according to the proportion, and adjusting the pH value to 4.5-6.5 to obtain uniform, transparent and light yellow liquid.
Compared with the prior art, the invention has the following beneficial effects:
the composition with the functions of inhibiting bacteria and removing blood stains has the quick antibacterial effect on three female frequently-infected bacteria such as escherichia coli, candida albicans and staphylococcus aureus by combining the stemona extract, the curcuma zedoary extract, the sweet wormwood extract, the gallnut extract and the duckweed extract which are prepared according to a certain proportion, and the antibacterial rate of the composition to the escherichia coli, the candida albicans and the staphylococcus aureus exceeds 80% within 2 min; meanwhile, the composition is matched with the soapberry extract and the plant protease in a certain proportion, so that the antibacterial effect of the soapberry extract and the plant protease cannot be affected, and the composition has a remarkable blood stain removing effect, and particularly has a very excellent blood stain removing effect on old blood stains. The components of the composition are natural plant components, are mild and non-irritating, and can be further used for preparing female underwear washing and protecting products.
Drawings
FIG. 1 shows the results of a blood stain removal test for a liquid laundry detergent prepared from the bacteriostatic blood stain removal composition of the present invention. The left side is the cleaning effect of a commercial underwear laundry detergent and the right side is the cleaning effect of the composition of example 11.
FIG. 2 shows the results of the physicochemical properties and detergency of the underwear washing liquid of the present invention.
FIG. 3 shows the results of the antibacterial effect detection of the underwear wash of the present invention.
FIG. 4 shows the result of the safety test of the underwear washing liquid of the present invention.
FIG. 5 is a graph showing the results of the skin irritation test of the underwear wash of the present invention.
Detailed Description
The invention is further illustrated in the following drawings and specific examples, which are not intended to limit the invention in any way. Unless specifically stated otherwise, the reagents, methods and apparatus employed in the present invention are those conventional in the art.
Reagents and materials used in the following examples are commercially available unless otherwise specified.
The raw materials used in the present invention may be obtained by homemade or purchased commercially. For example: stemona extract from Zhenghe (Guangzhou) biosciences, curcumae rhizoma extract from Zhenghe (Guangzhou) biosciences, herba Artemisiae Annuae extract from Zhenghe (Guangzhou) biosciences, galla chinensis extract from Zhenghe (Guangzhou) biosciences, herba Spirodelae extract from Zhenghe (Guangzhou) biosciences, soapberry extract from Zhenghe (Guangzhou) biosciences, papain from Jiangsu Kang Lai, bromelain from Jiangsu Kang Lai, pomegranate seed oil from Guangzhou Stokes biosciences, meinao oil from Guangzhou Stokes biosciences, herba Selaginellae extract from Zhenghen (Guangzhou) biosciences, and herba Duchesneae extract from Zhenghe (Guangzhou) biosciences.
The preparation methods of the stemona root extract, the curcuma zedoary extract, the sweet wormwood extract, the Chinese gall extract, the duckweed extract, the soapberry extract, the selaginella extract and the mock strawberry extract are as follows:
100g of Chinese herbal medicine is taken, 1000mL of distilled water is added, soaking is carried out for 2 hours, heating and boiling are carried out, then the decoction is continued for 30 minutes, and the Chinese herbal medicine liquid is filtered. Continuously adding distilled water with equal volume into the residue, decocting for 1 time by the same method, filtering, and discarding residue. Mixing the decoctions, centrifuging, collecting supernatant, concentrating to crude drug concentration of 50%, sub-packaging, and autoclaving at 121deg.C for 15min to obtain plant extracts.
Example 1
A composition with antibacterial and blood stain removing effects comprises the following components in parts by weight: 9 g of stemona extract, 9 g of curcuma zedoary extract, 15 g of sweet wormwood extract, 6 g of gallnut extract, 9 g of duckweed extract, 16 g of soapberry extract and 2g of papain.
The preparation method of the composition comprises the following steps: mixing the plant extracts with papain at a certain weight ratio, and stirring.
Example 2
A composition with antibacterial and blood stain removing effects comprises the following components in parts by weight: 6 g of stemona extract, 6 g of curcuma zedoary extract, 12 g of sweet wormwood extract, 4 g of gallnut extract, 6 g of duckweed extract, 14 g of soapberry extract and 1 g of papain.
The preparation method of the composition is the same as in example 1.
Example 3
A composition with antibacterial and blood stain removing effects comprises the following components in parts by weight: 11 g of stemona extract, 5 g of curcuma zedoary extract, 9 g of sweet wormwood extract, 7 g of gallnut extract, 6 g of duckweed extract, 12 g of soapberry extract and 0.5 g of papain.
The preparation method of the composition is the same as in example 1.
Example 4
A composition with antibacterial and blood stain removing effects comprises the following components in parts by weight: 5 g of stemona extract, 11 g of curcuma zedoary extract, 16 g of sweet wormwood extract, 3 g of gallnut extract, 11 g of duckweed extract, 16 g of soapberry extract and 2g of papain.
The preparation method of the composition is the same as in example 1.
Example 5
A composition with antibacterial and blood stain removing effects comprises the following components in parts by weight: 9 g of stemona extract, 9 g of curcuma zedoary extract, 15 g of sweet wormwood extract, 6 g of gallnut extract, 9 g of duckweed extract, 16 g of soapberry extract and 2g of bromelain.
The preparation method of the composition is the same as in example 1.
Example 6
A composition with antibacterial and blood stain removing effects comprises the following components in parts by weight: 9 g of stemona extract, 9 g of curcuma zedoary extract, 15 g of sweet wormwood extract, 6 g of gallnut extract, 9 g of duckweed extract, 16 g of soapberry extract, 2g of papain, 0.6 g of pomegranate seed oil, 0.6 g of merry-go-round oil and 6 g of selaginella extract.
The preparation method of the composition comprises the following steps:
(1) Mixing the plant extracts with papain in a weight ratio, and stirring.
(2) Mixing and dissolving the pomegranate seed oil, the vine fruit oil and the glycerol according to the proportion of 1:10, and then mixing with the mixture obtained in the step (1) according to the weight proportion, and uniformly stirring to obtain the pomegranate seed oil and vine fruit oil.
Example 7
A composition with antibacterial and blood stain removing effects comprises the following components in parts by weight: 9 g of stemona extract, 9 g of curcuma zedoary extract, 15 g of sweet wormwood extract, 6 g of gallnut extract, 9 g of duckweed extract, 16 g of soapberry extract, 2g of papain, 0.2 g of pomegranate seed oil, 0.2 g of merry-go-round oil and 4 g of selaginella extract.
The preparation of the composition was the same as in example 5.
Example 8
A composition with antibacterial and blood stain removing effects comprises the following components in parts by weight: 6 g of stemona extract, 6 g of curcuma zedoary extract, 12 g of sweet wormwood extract, 4 g of gallnut extract, 6 g of duckweed extract, 14 g of soapberry extract, 1 g of papain, 0.2 g of pomegranate seed oil, 0.2 g of merry-go-round oil and 4 g of selaginella extract.
The preparation of the composition was the same as in example 5.
Example 9
A composition with antibacterial and blood stain removing effects comprises the following components in parts by weight: 9 g of stemona extract, 9 g of curcuma zedoary extract, 15 g of sweet wormwood extract, 6 g of gallnut extract, 9 g of duckweed extract, 16 g of soapberry extract, 2g of papain, 0.6 g of pomegranate seed oil, 0.6 g of merry-go-round oil, 6 g of selaginella extract and 4 g of mock strawberry extract.
The preparation of the composition was the same as in example 5.
Example 10
A composition with antibacterial and blood stain removing effects is prepared from the following traditional Chinese medicine components in parts by weight: 9 g of stemona extract, 9 g of curcuma zedoary extract, 15 g of sweet wormwood extract, 6 g of gallnut extract, 9 g of duckweed extract, 16 g of soapberry extract, 2g of papain, 0.6 g of pomegranate seed oil, 0.6 g of merry-go-round oil, 6 g of selaginella extract and 2g of mock strawberry extract.
The preparation of the composition was the same as in example 5.
Comparative example 1
A composition comprising the following components by weight: 9 g of stemona extract, 9 g of curcuma zedoary extract, 6 g of gallnut extract, 16 g of soapberry extract and 2g of papain.
The preparation method of the composition is the same as in example 1.
Comparative example 2
A composition comprising the following components by weight: 9 g of stemona extract, 9 g of curcuma zedoary extract, 6 g of gallnut extract, 9 g of duckweed extract, 16 g of soapberry extract and 2g of papain.
The preparation method of the composition is the same as in example 1.
Comparative example 3
A composition comprising the following components by weight: 9 g of stemona extract, 9 g of curcuma zedoary extract, 15 g of sweet wormwood extract, 6 g of Chinese gall extract, 16 g of soapberry extract and 2g of papain.
The preparation method of the composition is the same as in example 1.
Comparative example 4
A composition comprising the following components by weight: 4 g of stemona extract, 12 g of curcuma zedoary extract, 8 g of sweet wormwood extract, 8 g of gallnut extract, 5 g of duckweed extract, 11 g of soapberry extract and 2g of papain.
The preparation method of the composition is the same as in example 1.
Comparative example 5
A composition comprising the following components by weight: 12 g of stemona extract, 4 g of curcuma zedoary extract, 17 g of sweet wormwood extract, 2g of gallnut extract, 12 g of duckweed extract, 11 g of soapberry extract and 2g of papain.
The preparation method of the composition is the same as in example 1.
Comparative example 6
A composition comprising the following components by weight: 9 g of stemona extract, 9 g of curcuma zedoary extract, 15 g of sweet wormwood extract, 6 g of gallnut extract, 9 g of duckweed extract and 2g of papain.
Comparative example 7
A composition comprising the following components by weight: 9 g of stemona extract, 9 g of curcuma zedoary extract, 15 g of sweet wormwood extract, 6 g of gallnut extract, 9 g of duckweed extract and 16 g of soapberry extract.
Test example 1 bacteriostasis test
The testing method comprises the following steps: the test method of the rapid antibacterial effect on candida albicans, escherichia coli and staphylococcus aureus is carried out by referring to the antibacterial performance test method of the dissolution antibacterial (anti-bacteria) product of annex C4 of GB 15979-2022 hygienic Standard for disposable hygienic products, test samples are antibacterial and blood stain removing compositions prepared in each example and comparative example, escherichia coli ATCC-25922, staphylococcus aureus ATCC-6538 and candida albicans ATCC-10231 are used as test strains, the action time is 2min, and each sample is repeated three times, so that the average value is calculated. The specific test results are shown in Table 1.
Table 1 results of antibacterial liquid test
Note that: GB15979-2002 hygienic standards for disposable hygienic products, appendix C4 specifies: the antibacterial rate is more than or equal to 50-90%, and the product has antibacterial effect; the bacteriostasis rate is more than or equal to 90%, and the product has stronger bacteriostasis effect.
As can be seen from Table 1, the composition of examples 1-5 of the invention has a rapid antibacterial effect on Escherichia coli, candida albicans and Staphylococcus aureus, the antibacterial rate on Escherichia coli, candida albicans and Staphylococcus aureus can reach 80-99.9% within 2min, and meanwhile, the antibacterial effect of the combination of the soapy extract and the plant protease can not be influenced; it can be seen from examples 6 to 10 that the addition of other ingredients having skin care and garment softening properties to the compositions of examples 1 to 5 does not affect the bacteriostatic effect. As can be seen from comparative examples 1-5, when the antibacterial composition lacks duckweed and/or sweet wormwood, or the amounts of the components are not within the range of the compositions of examples 1-5, the rapid antibacterial effect is greatly reduced, and the rapid antibacterial effect on escherichia coli, candida albicans and staphylococcus aureus cannot be achieved, which indicates that the antibacterial composition of the invention needs specific components and proportions to achieve rapid antibacterial.
Test example 2 blood stain removal test
(1) Decontamination test
The testing method comprises the following steps: referring to the liquid detergent for QB/T1224-2012 clothing, JB-01 carbon black dirt cloth, JB-02 protein dirt cloth and JB-03 sebum dirt cloth. Judgment standard: the detergency of the standard liquid laundry detergent is more than or equal to 1.0, and the result is more than or equal to 1.0.
Table 2 detergency test results
As can be seen from Table 2, the compositions of examples 1-10 of the present invention all had JB-01, JB-02 and JB-03 greater than the standard laundry detergent and had potent detergency, which was greatly reduced when the compositions lacked soapstock extract or papain.
(2) Blood stain removal test
Method 1:0.5mL of fresh duck blood is dripped into the middle of standard bleached pure cotton cloth with the area of 6cm multiplied by 6cm, and naturally dried at the ambient temperature of 30 ℃ for 48 hours for later use.
In a vertical soil release tester, 2g of the composition of example (or comparative example) was taken, ultrapure water was added to 1000g, after heating to 30 ℃, two pieces of blood stain were added, and then stirring was started, and after 20 minutes, it was stopped. And taking out the blood stain cloth, cleaning, airing and measuring whiteness.
TABLE 3 blood stain removal test results
As can be seen from the results of Table 3, the compositions of examples 1 to 10 of the present invention have very excellent removal effects on old blood stains, while the removal effects on old blood stains are significantly reduced when the soapwort extract or papain is absent from the composition.
Method 2:0.5mL of fresh duck blood is dripped into two layers of fabric at the crotch part of pure cotton, naturally dried for 48 hours, and then rubbed with 2g of the composition of the example 1 and the comparative example 6 for 45 seconds, and then rinsed.
The cleaning result of the method 2 is shown in fig. 1, the left side is the cleaning effect of a commercial underwear laundry detergent, and the right side is the cleaning effect of the composition in the embodiment 11 of the invention, so that the antibacterial blood stain removing composition of the invention has a significantly better old blood stain removing effect than the prior commercial underwear laundry detergent.
Example 11
An antibacterial and blood stain removing underwear washing liquid comprises the following components in percentage by weight: 10% of the composition of example 9, 20% of a surfactant, 5% of a stabilizer, 2% of a water softener, 2% of a humectant, 0.2% of a pH adjustor, and 60.8% of purified water.
The surfactant is 6.0% of alkyl glycoside, 4.0% of cocamidopropyl betaine, 5.0% of fatty alcohol polyoxyethylene ether sodium sulfate, 2.0% of laurinol polyoxyethylene ether and 3.0% of isomeric alcohol polyoxyethylene ether.
The stabilizer is sorbitol.
The water softener is 1.0% sodium citrate and 1.0% sodium gluconate.
The humectant is glycerin.
The pH regulator is citric acid.
The preparation method of the antibacterial and blood stain removing underwear washing liquid comprises the following steps:
(1) Mixing enough water, sodium citrate, sodium gluconate, glycerol and fatty alcohol-polyoxyethylene ether sodium sulfate according to a certain proportion, and uniformly stirring.
(2) Adding alkyl glucoside, laurinol polyoxyethylene ether, isomeric alcohol polyoxyethylene ether and sorbitol according to a certain proportion, uniformly stirring.
(3) Adding cocamidopropyl betaine according to the proportion, and stirring uniformly.
(4) The composition is added according to the proportion and stirred uniformly.
(5) Citric acid is added according to the proportion, and the pH value is adjusted to 4.5-6.5, so that uniform, transparent and light yellow liquid is obtained.
Example 12
An antibacterial and blood stain removing underwear washing liquid comprises the following components in percentage by weight: 7% of the composition described in example 10, 17% of a surfactant, 4% of a stabilizer, 2% of a water softener, 2% of a humectant, 0.1% of a pH adjustor, and 67.9% of purified water.
The surfactant is prepared by removing the isomeric alcohol polyoxyethylene ether, and the rest is the same as that in the example 11; the kinds of the stabilizer, water softener, humectant and pH adjustor were the same as in example 11.
The preparation method of the antibacterial and blood stain removing underwear washing liquid is the same as that of the example 11.
Example 13
An antibacterial and blood stain removing underwear washing liquid comprises the following components in percentage by weight: comprises 5% of the composition described in example 10, 15% of surfactant, 2% of stabilizer, 1% of water softener, 1% of humectant, 0.05% of pH regulator and 75.95% of purified water.
The surfactant is prepared by removing sodium fatty alcohol polyoxyethylene ether sulfate, and the rest is the same as that of the example 11; the kinds of the stabilizer, water softener, humectant and pH adjustor were the same as in example 11.
The preparation method of the antibacterial and blood stain removing underwear washing liquid is the same as that of the example 11.
Test example 3 underwear wash test
The underwear wash prepared in example 11 was tested as follows:
(1) Underwear washing liquid physicochemical property and detergency detection
The department of technology service (guangzhou) stock company is commissioned to conduct the test. The specific detection results are shown in figure 2, and the results show that the detergency JB-01, JB-02 and JB-03 of the washing agent are all larger than that of the standard washing liquid and are 1.2-4.1 times of that of the standard washing liquid, and meanwhile, the underwear washing liquid is in a weak acid formula, the pH=6.7, accords with the pH of human epidermis, has small irritation to the skin of a human body and does not feel dry.
(2) Antibacterial effect detection for underwear washing liquid
Entrusting test mechanism: the method for detecting the antibacterial effect of the microorganism institute priority company in Guangzhou city is carried out by referring to the antibacterial performance test method of the dissolution antibacterial (antibacterial) product of annex C4 of GB 15979-2022 sanitary Standard for Disposable sanitary products, and takes escherichia coli ATCC-25922, staphylococcus aureus ATCC-6538 and candida albicans ATCC-10231 as test strains, the action time is 2min, each sample is repeated three times, and the average value is calculated. The specific test result is shown in figure 3, which shows that the underwear washing liquid of the invention can reach 99.9 percent of antibacterial rate on escherichia coli, candida albicans and staphylococcus aureus after 2 minutes of action, and accords with the specification of the Q/CBBU011-2019 natural authentication antibacterial laundry detergent.
(3) Underwear washing liquid safety inspection
The microorganism index of underwear washing liquid is detected by the commission Guangzhou city microorganism research institute, the detection basis and method are GB15979-2002 appendix B of disposable hygienic product hygienic Standard, and microorganism detection indexes (bacterial colony count, fungus colony count, coliform group, staphylococcus aureus, hemolytic streptococcus and Pseudomonas aeruginosa). The specific test result is shown in fig. 4, which shows that the underwear washing liquid meets the safety requirement and meets the requirements of the Q/CBBU011-2019 natural authentication antibacterial liquid laundry detergent.
(4) Underwear wash skin irritation test
The department of technology service (guangzhou) stock company was commissioned to conduct skin irritation tests. Specific test results are shown in fig. 5, and according to the skin irritation intensity grading standard in 2002 edition of disinfection technical Specification, the multiple complete skin irritation test results of the underwear washing liquid of the invention on rabbits are as follows: the disinfectant is non-irritating and meets the requirements of 2002 edition 2.3.13.1.

Claims (13)

1. The antibacterial blood stain removing composition is characterized by comprising the following components in parts by weight: 9-11 parts of stemona extract, 9-11 parts of curcuma zedoary extract, 9-15 parts of sweet wormwood extract, 4-7 parts of Chinese gall extract, 6-9 parts of duckweed extract, 14-16 parts of soapberry extract and 1-2 parts of plant protease; the plant protease is papain or bromelain; the preparation method of the plant extracts comprises soaking 100g of Chinese herbal medicine in 1000mL of distilled water for 2 hr, heating and boiling, decocting for 30min, and filtering to obtain Chinese medicinal liquid; continuously adding distilled water with equal volume into the residue, decocting for 1 time by the same method, filtering, and discarding residue; mixing the decoctions, centrifuging, collecting supernatant, concentrating to crude drug concentration of 50%, sub-packaging, and sterilizing at 121deg.C for 15 min.
2. The composition of claim 1, comprising the following components in parts by weight: 9 parts of stemona extract, 9 parts of curcuma zedoary extract, 15 parts of sweet wormwood extract, 6 parts of gallnut extract, 9 parts of duckweed extract, 16 parts of soapberry extract and 2 parts of plant protease.
3. The composition of claim 1, further comprising 0.2 to 0.6 parts of pomegranate seed oil.
4. The composition of claim 1, further comprising 0.2 to 0.6 parts of merry go round robin oil.
5. The composition according to claim 1, wherein the composition further comprises 4 to 6 parts of selaginella extract; the herba Selaginellae extract is prepared by soaking 100g of Chinese herbal medicine in 1000mL of distilled water for 2 hr, boiling, decocting for 30min, and filtering to obtain Chinese medicinal liquid; continuously adding distilled water with equal volume into the residue, decocting for 1 time by the same method, filtering, and discarding residue; mixing the decoctions, centrifuging, collecting supernatant, concentrating to crude drug concentration of 50%, sub-packaging, and sterilizing at 121deg.C for 15 min.
6. The composition of claim 1, further comprising 2 to 4 parts of a mock strawberry extract; the preparation method of the Indian mockstrawberry herb extract comprises the steps of taking 100g of Chinese herbal medicine, adding 1000mL of distilled water, soaking for 2 hours, continuously decocting for 30 minutes after heating and boiling, and filtering the Chinese herbal medicine liquid; continuously adding distilled water with equal volume into the residue, decocting for 1 time by the same method, filtering, and discarding residue; mixing the decoctions, centrifuging, collecting supernatant, concentrating to crude drug concentration of 50%, sub-packaging, and sterilizing at 121deg.C for 15 min.
7. Use of a composition according to any one of claims 1 to 6 for the preparation of a bacteriostatic blood stain-removing washing product.
8. An antibacterial and blood stain removing underwear washing liquid is characterized by comprising the following components in percentage by weight: 5-10% of the composition according to any one of claims 1-6, 15-20% of surfactant, 2-5% of stabilizer, 1-2% of water softener, 1-2% of humectant, 0.05-0.2% of pH regulator and the balance of purified water.
9. The underwear washing liquid according to claim 8, wherein the surfactant is any one or more of alkyl glycoside, cocamidopropyl betaine, sodium fatty alcohol polyoxyethylene ether sulfate, and laureth.
10. The underwear wash of claim 8, wherein the stabilizer is sorbitol.
11. The underwear wash according to claim 8, wherein the water softener is sodium citrate and/or sodium gluconate.
12. The underwear wash of claim 8, wherein the humectant is glycerin.
13. The underwear wash according to claim 8, wherein the pH adjustor is citric acid.
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