CN115252481A - Repairing and whitening essential oil composition and preparation method thereof - Google Patents
Repairing and whitening essential oil composition and preparation method thereof Download PDFInfo
- Publication number
- CN115252481A CN115252481A CN202210979033.XA CN202210979033A CN115252481A CN 115252481 A CN115252481 A CN 115252481A CN 202210979033 A CN202210979033 A CN 202210979033A CN 115252481 A CN115252481 A CN 115252481A
- Authority
- CN
- China
- Prior art keywords
- essential oil
- percent
- oil composition
- composition
- weight
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000000341 volatile oil Substances 0.000 title claims abstract description 115
- 239000000203 mixture Substances 0.000 title claims abstract description 54
- 230000002087 whitening effect Effects 0.000 title claims abstract description 22
- 238000002360 preparation method Methods 0.000 title claims abstract description 11
- 235000009024 Ceanothus sanguineus Nutrition 0.000 claims abstract description 13
- 235000005979 Citrus limon Nutrition 0.000 claims abstract description 13
- 244000131522 Citrus pyriformis Species 0.000 claims abstract description 13
- 241000208152 Geranium Species 0.000 claims abstract description 13
- 244000178870 Lavandula angustifolia Species 0.000 claims abstract description 13
- 235000010663 Lavandula angustifolia Nutrition 0.000 claims abstract description 13
- 240000003553 Leptospermum scoparium Species 0.000 claims abstract description 13
- 235000015459 Lycium barbarum Nutrition 0.000 claims abstract description 13
- 239000001102 lavandula vera Substances 0.000 claims abstract description 13
- 235000018219 lavender Nutrition 0.000 claims abstract description 13
- 240000003538 Chamaemelum nobile Species 0.000 claims abstract description 8
- 235000007866 Chamaemelum nobile Nutrition 0.000 claims abstract description 8
- 239000001224 daucus carota l. seed absolute Substances 0.000 claims abstract description 8
- 230000008439 repair process Effects 0.000 claims abstract description 5
- 239000002537 cosmetic Substances 0.000 claims description 17
- 239000003921 oil Substances 0.000 claims description 11
- 235000019198 oils Nutrition 0.000 claims description 8
- 238000000034 method Methods 0.000 claims description 4
- 230000000694 effects Effects 0.000 abstract description 21
- XUMBMVFBXHLACL-UHFFFAOYSA-N Melanin Chemical compound O=C1C(=O)C(C2=CNC3=C(C(C(=O)C4=C32)=O)C)=C2C4=CNC2=C1C XUMBMVFBXHLACL-UHFFFAOYSA-N 0.000 abstract description 12
- 150000001875 compounds Chemical class 0.000 abstract description 7
- 206010061218 Inflammation Diseases 0.000 abstract description 3
- 230000004054 inflammatory process Effects 0.000 abstract description 3
- 230000002401 inhibitory effect Effects 0.000 abstract description 3
- 230000037380 skin damage Effects 0.000 abstract description 2
- 206010042496 Sunburn Diseases 0.000 description 11
- 102000003425 Tyrosinase Human genes 0.000 description 10
- 108060008724 Tyrosinase Proteins 0.000 description 10
- 238000003756 stirring Methods 0.000 description 9
- 230000005764 inhibitory process Effects 0.000 description 8
- 239000000243 solution Substances 0.000 description 8
- 206010040844 Skin exfoliation Diseases 0.000 description 7
- GVJHHUAWPYXKBD-UHFFFAOYSA-N (±)-α-Tocopherol Chemical compound OC1=C(C)C(C)=C2OC(CCCC(C)CCCC(C)CCCC(C)C)(C)CCC2=C1C GVJHHUAWPYXKBD-UHFFFAOYSA-N 0.000 description 6
- 206010015150 Erythema Diseases 0.000 description 6
- DNIAPMSPPWPWGF-UHFFFAOYSA-N Propylene glycol Chemical compound CC(O)CO DNIAPMSPPWPWGF-UHFFFAOYSA-N 0.000 description 6
- 231100000321 erythema Toxicity 0.000 description 6
- 238000002474 experimental method Methods 0.000 description 6
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 6
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 description 5
- 238000002156 mixing Methods 0.000 description 5
- 238000001816 cooling Methods 0.000 description 4
- 239000006071 cream Substances 0.000 description 4
- 238000010438 heat treatment Methods 0.000 description 4
- 229940119170 jojoba wax Drugs 0.000 description 4
- 230000009467 reduction Effects 0.000 description 4
- 241000196324 Embryophyta Species 0.000 description 3
- OUYCCCASQSFEME-QMMMGPOBSA-N L-tyrosine Chemical compound OC(=O)[C@@H](N)CC1=CC=C(O)C=C1 OUYCCCASQSFEME-QMMMGPOBSA-N 0.000 description 3
- 229930003427 Vitamin E Natural products 0.000 description 3
- 206010000496 acne Diseases 0.000 description 3
- 239000007853 buffer solution Substances 0.000 description 3
- 230000008021 deposition Effects 0.000 description 3
- 238000011049 filling Methods 0.000 description 3
- WIGCFUFOHFEKBI-UHFFFAOYSA-N gamma-tocopherol Natural products CC(C)CCCC(C)CCCC(C)CCCC1CCC2C(C)C(O)C(C)C(C)C2O1 WIGCFUFOHFEKBI-UHFFFAOYSA-N 0.000 description 3
- 239000002994 raw material Substances 0.000 description 3
- OUYCCCASQSFEME-UHFFFAOYSA-N tyrosine Natural products OC(=O)C(N)CC1=CC=C(O)C=C1 OUYCCCASQSFEME-UHFFFAOYSA-N 0.000 description 3
- 235000019165 vitamin E Nutrition 0.000 description 3
- 239000011709 vitamin E Substances 0.000 description 3
- 229940046009 vitamin E Drugs 0.000 description 3
- IIZPXYDJLKNOIY-JXPKJXOSSA-N 1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphocholine Chemical compound CCCCCCCCCCCCCCCC(=O)OC[C@H](COP([O-])(=O)OCC[N+](C)(C)C)OC(=O)CCC\C=C/C\C=C/C\C=C/C\C=C/CCCCC IIZPXYDJLKNOIY-JXPKJXOSSA-N 0.000 description 2
- QCDWFXQBSFUVSP-UHFFFAOYSA-N 2-phenoxyethanol Chemical compound OCCOC1=CC=CC=C1 QCDWFXQBSFUVSP-UHFFFAOYSA-N 0.000 description 2
- LXAHHHIGZXPRKQ-UHFFFAOYSA-N 5-fluoro-2-methylpyridine Chemical compound CC1=CC=C(F)C=N1 LXAHHHIGZXPRKQ-UHFFFAOYSA-N 0.000 description 2
- 208000002874 Acne Vulgaris Diseases 0.000 description 2
- NIXOWILDQLNWCW-UHFFFAOYSA-N Acrylic acid Chemical compound OC(=O)C=C NIXOWILDQLNWCW-UHFFFAOYSA-N 0.000 description 2
- 206010067484 Adverse reaction Diseases 0.000 description 2
- 244000144725 Amygdalus communis Species 0.000 description 2
- 235000011437 Amygdalus communis Nutrition 0.000 description 2
- 241000219357 Cactaceae Species 0.000 description 2
- 102000004190 Enzymes Human genes 0.000 description 2
- 108090000790 Enzymes Proteins 0.000 description 2
- VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 description 2
- 206010033733 Papule Diseases 0.000 description 2
- 241000220317 Rosa Species 0.000 description 2
- 229920002125 Sokalan® Polymers 0.000 description 2
- GSEJCLTVZPLZKY-UHFFFAOYSA-N Triethanolamine Chemical compound OCCN(CCO)CCO GSEJCLTVZPLZKY-UHFFFAOYSA-N 0.000 description 2
- 230000006838 adverse reaction Effects 0.000 description 2
- 239000008168 almond oil Substances 0.000 description 2
- 229960001631 carbomer Drugs 0.000 description 2
- 239000000969 carrier Substances 0.000 description 2
- 230000008859 change Effects 0.000 description 2
- 238000006243 chemical reaction Methods 0.000 description 2
- 239000003240 coconut oil Substances 0.000 description 2
- 235000019864 coconut oil Nutrition 0.000 description 2
- 230000035618 desquamation Effects 0.000 description 2
- 238000007599 discharging Methods 0.000 description 2
- 239000012153 distilled water Substances 0.000 description 2
- 239000003974 emollient agent Substances 0.000 description 2
- 235000011187 glycerol Nutrition 0.000 description 2
- 239000008169 grapeseed oil Substances 0.000 description 2
- 235000010445 lecithin Nutrition 0.000 description 2
- 239000000787 lecithin Substances 0.000 description 2
- 229940067606 lecithin Drugs 0.000 description 2
- 238000002844 melting Methods 0.000 description 2
- 230000008018 melting Effects 0.000 description 2
- GLDOVTGHNKAZLK-UHFFFAOYSA-N octadecan-1-ol Chemical compound CCCCCCCCCCCCCCCCCCO GLDOVTGHNKAZLK-UHFFFAOYSA-N 0.000 description 2
- 229960005323 phenoxyethanol Drugs 0.000 description 2
- 239000000049 pigment Substances 0.000 description 2
- 239000010667 rosehip oil Substances 0.000 description 2
- 229940092258 rosemary extract Drugs 0.000 description 2
- 235000020748 rosemary extract Nutrition 0.000 description 2
- 239000001233 rosmarinus officinalis l. extract Substances 0.000 description 2
- 230000002195 synergetic effect Effects 0.000 description 2
- 235000015112 vegetable and seed oil Nutrition 0.000 description 2
- 239000003981 vehicle Substances 0.000 description 2
- 238000002965 ELISA Methods 0.000 description 1
- QWCKQJZIFLGMSD-VKHMYHEASA-N L-alpha-aminobutyric acid Chemical compound CC[C@H](N)C(O)=O QWCKQJZIFLGMSD-VKHMYHEASA-N 0.000 description 1
- VCUFZILGIRCDQQ-KRWDZBQOSA-N N-[[(5S)-2-oxo-3-(2-oxo-3H-1,3-benzoxazol-6-yl)-1,3-oxazolidin-5-yl]methyl]-2-[[3-(trifluoromethoxy)phenyl]methylamino]pyrimidine-5-carboxamide Chemical group O=C1O[C@H](CN1C1=CC2=C(NC(O2)=O)C=C1)CNC(=O)C=1C=NC(=NC=1)NCC1=CC(=CC=C1)OC(F)(F)F VCUFZILGIRCDQQ-KRWDZBQOSA-N 0.000 description 1
- 208000028990 Skin injury Diseases 0.000 description 1
- 238000002835 absorbance Methods 0.000 description 1
- 125000003118 aryl group Chemical group 0.000 description 1
- 238000003556 assay Methods 0.000 description 1
- 230000015572 biosynthetic process Effects 0.000 description 1
- 239000000872 buffer Substances 0.000 description 1
- 229940081733 cetearyl alcohol Drugs 0.000 description 1
- 229940082500 cetostearyl alcohol Drugs 0.000 description 1
- 238000004140 cleaning Methods 0.000 description 1
- 230000000052 comparative effect Effects 0.000 description 1
- 229940125810 compound 20 Drugs 0.000 description 1
- 239000003581 cosmetic carrier Substances 0.000 description 1
- 230000003247 decreasing effect Effects 0.000 description 1
- 238000007865 diluting Methods 0.000 description 1
- 238000010790 dilution Methods 0.000 description 1
- 239000012895 dilution Substances 0.000 description 1
- BNIILDVGGAEEIG-UHFFFAOYSA-L disodium hydrogen phosphate Chemical compound [Na+].[Na+].OP([O-])([O-])=O BNIILDVGGAEEIG-UHFFFAOYSA-L 0.000 description 1
- 238000004821 distillation Methods 0.000 description 1
- 235000013399 edible fruits Nutrition 0.000 description 1
- 230000001804 emulsifying effect Effects 0.000 description 1
- -1 facial cleanser Substances 0.000 description 1
- 230000001815 facial effect Effects 0.000 description 1
- 238000009472 formulation Methods 0.000 description 1
- 229960005150 glycerol Drugs 0.000 description 1
- JAXFJECJQZDFJS-XHEPKHHKSA-N gtpl8555 Chemical compound OC(=O)C[C@H](N)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](C(C)C)C(=O)N1CCC[C@@H]1C(=O)N[C@H](B1O[C@@]2(C)[C@H]3C[C@H](C3(C)C)C[C@H]2O1)CCC1=CC=C(F)C=C1 JAXFJECJQZDFJS-XHEPKHHKSA-N 0.000 description 1
- 238000000338 in vitro Methods 0.000 description 1
- 239000007788 liquid Substances 0.000 description 1
- 239000006210 lotion Substances 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 230000008099 melanin synthesis Effects 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 229910000403 monosodium phosphate Inorganic materials 0.000 description 1
- 235000019799 monosodium phosphate Nutrition 0.000 description 1
- 239000013642 negative control Substances 0.000 description 1
- 230000037311 normal skin Effects 0.000 description 1
- 239000004006 olive oil Substances 0.000 description 1
- 235000008390 olive oil Nutrition 0.000 description 1
- 230000019612 pigmentation Effects 0.000 description 1
- 229960004063 propylene glycol Drugs 0.000 description 1
- 230000002829 reductive effect Effects 0.000 description 1
- 239000002453 shampoo Substances 0.000 description 1
- 239000002884 skin cream Substances 0.000 description 1
- AJPJDKMHJJGVTQ-UHFFFAOYSA-M sodium dihydrogen phosphate Chemical compound [Na+].OP(O)([O-])=O AJPJDKMHJJGVTQ-UHFFFAOYSA-M 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 230000036561 sun exposure Effects 0.000 description 1
- 208000024891 symptom Diseases 0.000 description 1
- OULAJFUGPPVRBK-UHFFFAOYSA-N tetratriacontyl alcohol Natural products CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCO OULAJFUGPPVRBK-UHFFFAOYSA-N 0.000 description 1
- 229930003231 vitamin Natural products 0.000 description 1
- 229940088594 vitamin Drugs 0.000 description 1
- 235000013343 vitamin Nutrition 0.000 description 1
- 239000011782 vitamin Substances 0.000 description 1
- 150000003722 vitamin derivatives Chemical class 0.000 description 1
- 239000007762 w/o emulsion Substances 0.000 description 1
- 238000005303 weighing Methods 0.000 description 1
Images
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/92—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
- A61K8/922—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of vegetable origin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/004—Aftersun preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/02—Preparations for care of the skin for chemically bleaching or whitening the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/59—Mixtures
- A61K2800/592—Mixtures of compounds complementing their respective functions
- A61K2800/5922—At least two compounds being classified in the same subclass of A61K8/18
Abstract
The invention relates to a repairing and whitening essential oil formula composition and a preparation method thereof. The invention relates to a compound essential oil composition with whitening and after-sun repairing effects, which comprises the following components in percentage by weight: 30-38% of lavender essential oil, 16-23% of lemon essential oil, 14-22% of tea tree essential oil, 10-16% of geranium essential oil, 5-13% of Roman chamomile essential oil and 4-8% of carrot seed oil. The essential oil composition has an unexpected effect on inhibiting increase of various cell melanin caused by solarization, skin damage and inflammation, and has a remarkable effect on whitening and after-sun repair.
Description
Technical Field
The invention belongs to the field of skin care products, and particularly relates to an essential oil composition with after-sun repairing and whitening effects.
Background
The plant essential oil is volatile aromatic substance prepared from flower, stem, leaf, fruit, peel of plant by specific water distillation and squeezing. Plant essential oils contain complex structures (tens to hundreds) of compounds, and the combination of different essential oil compounds can produce very different effects.
Whitening is an important requirement in the field of skin care products in China. Many essential oils are tentatively applied to whitening skin care products, including some single and compound essential oil combinations. Due to uncertainty of efficacy of the essential oil combination, the single-component essential oil and the compound essential oil can not achieve the expected whitening effect in many attempts. For example, CN105686981A relates to whitening acne-removing essential oil, and the whitening acne-removing effect is claimed to be remarkable. But the inventor verifies that the expected significant effect is not achieved.
Disclosure of Invention
According to the invention, a large number of essential oil components are widely researched, and finally, a specific essential oil composition is obtained, which has an unexpected effect on inhibiting increase of various cell melanin caused by solarization, skin damage and inflammation, and has a remarkable effect on whitening and after-sun repair.
It is verified that the effect comes from the synergistic effect of the specific essential oil composition under the precise proportion.
The invention relates to a compound essential oil composition with whitening or after-sun repairing functions, which comprises the following components in parts by weight:
lavender essential oil: 30 to 38 percent
Lemon essential oil: 16-23 percent
Tea tree essential oil: 14 to 22 percent
Geranium essential oil: 10-16%
Roman chamomile essential oil: 5 to 13 percent of
Carrot seed oil: 4 to 8 percent.
Preferably, the essential oil composition consists of the six components.
Preferably, the essential oil composition comprises the following components in parts by weight:
lavender essential oil: 34 to 36 percent
Lemon essential oil: 19 to 21 percent
Tea tree essential oil: 17 to 19 percent
Geranium essential oil: 12 to 14 percent
Roman chamomile essential oil: 8 to 10 percent of
Carrot seed oil: 5 to 7 percent.
Preferably, the essential oil composition consists of the above six components.
More preferably, the essential oil composition comprises the following components in weight ratio:
34.5 percent of lavender essential oil
Lemon essential oil: 19.5 percent
Tea tree essential oil: 18 percent
Geranium essential oil: 13 percent of
Roman chamomile essential oil: 9 percent of
Carrot seed oil: 6 percent.
Preferably, the essential oil composition consists of the six components.
The preparation method of the essential oil composition comprises the following steps: the essential oil components are added in a container in portions or simultaneously, and mixed or stirred (e.g., for 10 to 30 minutes, e.g., for 20 minutes) at room temperature until uniform to obtain the essential oil composition of the present invention.
The essential oil composition can be directly or indirectly added into a cosmetically acceptable carrier according to a certain content, can reduce pigmentation caused by inflammation and the like, has a remarkable whitening effect, and has a remarkable after-sun repairing effect. The content is preferably more than 0% to 30% by weight or less, more preferably 1% to 20% by weight, and still more preferably 2 to 6% by weight. In one embodiment of the invention, the content is 2.5wt%. In one embodiment of the present invention, the content is 5wt%. In another embodiment of the present invention, the content is 10wt%. In another embodiment of the present invention, said content is 20wt%.
The cosmetically acceptable carrier is divided into the following types: water-oil emulsified type (cream), pure oil type (essential oil), and the like.
Common water-oil emulsified carriers for cosmetics include: oil-containing astringent, skin cream, skin lotion, facial cleanser, shampoo, cleaning cream, etc.
Common pure oil type carriers include: massage oil, skin moistening oil, makeup remover, etc.
One preparation method of the cosmetic composition of the present invention is: the cosmetically acceptable carrier components are mixed and dissolved in portions or simultaneously in one or more containers, and the essential oil composition of the invention is added to the obtained carrier in accordance with the above-mentioned contents.
For example, the following table illustrates a cosmetic composition of the present invention, wherein an exemplary neat oil (emollient oil) cosmetic carrier of the present invention comprises the following components 1-7:
the preparation steps of the exemplary cosmetic compositions of the present invention shown in the above table are:
sequentially adding the components 1, 2, 3, 4 and 5 into a container, and continuously stirring uniformly at room temperature; after the components are completely mixed, the components 6, 7 and 8 are added in sequence or simultaneously, stirred for about 20 minutes or until the components are uniform, discharged and filled. For example, the following table illustrates one cosmetic composition of the present invention, wherein an exemplary water-in-oil emulsion (emollient cream) cosmetic vehicle of the present invention comprises the following components 1-14:
for example, the preparation steps for the exemplary cosmetic compositions of the present invention shown in the above table are:
dissolving the components 1, 2, 3, 4, 11 and 12 in water, stirring in a container to mix uniformly, and heating to 80 ℃; mixing the components 5, 6, 7, 8, 9 and 10 in another container, heating to 80 ℃ and melting to obtain uniform liquid; mixing and homogenizing the two solutions for 3-5 minutes, fully emulsifying uniformly, and continuously stirring and cooling to below 40 ℃; and then sequentially adding 13, 14 and 15, stirring, uniformly mixing, cooling to room temperature and filling.
Unless otherwise indicated, all percentages stated herein are by weight.
The following examples further describe and demonstrate exemplary embodiments within the scope of the present invention. These examples are for illustration only and should not be construed as limitations of the present invention, as many variations thereof are possible without departing from its spirit and scope. Various modifications of the invention in addition to those shown and described herein will be apparent to those skilled in the art and are intended to fall within the scope of the appended claims.
Drawings
Figure 1 shows effect data for an embodiment of the invention.
Detailed description of the preferred embodiments
The essential oil raw materials meet the requirements of catalogues of used cosmetic raw materials (2021 edition), and meet the safety technical specifications of the cosmetic raw materials.
Example 1:
the invention relates to a repairing and whitening essential oil composition which comprises the following components in percentage by weight:
34.5 percent of lavender essential oil
Lemon essential oil: 19.5 percent
Tea tree essential oil: 18 percent
Geranium essential oil: 13 percent of
Roman chamomile essential oil: 9 percent of
Carrot seed oil: 6 percent of
The preparation method comprises the following steps: adding the essential oil components into a container in batches, and stirring at room temperature for 20 minutes or until uniform to obtain the essential oil composition of the invention.
Example 2:
a whitening essential oil cosmetic containing the essential oil composition is provided. The weight percentage of the components is as follows:
essential oil composition of example 1 10%
Coconut oil 48.5%
Jojoba oil 22%
Sweet almond oil 13%
Rose hip oil 5%
Cactus seed oil 1%
Rosemary extract 0.25%;
vitamin E0.25%
The preparation method comprises the following steps:
sequentially adding coconut oil, jojoba oil, sweet almond oil, rose hip oil and cactus seed oil into a container, and continuously stirring at room temperature; after the components are completely mixed, adding the rosemary extract, the vitamin E and the essential oil composition in the embodiment 1, stirring for 20 minutes or until the mixture is uniform, discharging and filling.
Performance experiment 1:
this experiment investigated the whitening and spot-removing effects of the product of the present invention on the skin of the subject.
30 volunteers (subjects) were randomly selected to try the essential oil component of the present invention.
The standard of the test subject is 30-60 years old male or female, the test part is an arm or a face, the test part has obvious color deposition and color spots, and the test subject does not use whitening products within 1 month.
The using method comprises the following steps: a proper amount of the product of example 2 is smeared on a test part, the test part is smeared once in the morning and at night for 8 weeks, and the uncomfortable feeling and the adverse reaction condition are recorded.
The skin color before and after the test and the control part (namely the part which is near the test part and also has obvious color deposition or color spots but is not coated with the product) are evaluated by adopting a standard skin color card, and the color change before and after the test is recorded and compared with the score. The skin color card is classified into 1-10 grades by chroma, and the lower the score, the whiter the skin.
As a result: no discomfort or adverse reactions occurred at the test sites for all subjects. Before use, in 30 subjects, the maximum value of the color chip is 10, the minimum value is 4, and the average value is 7; after 8 weeks of continuous use of the product of example 2, the subjects had a maximum of 7, a minimum of 2 and a mean of 4. The color spots and color deposition of the test parts of 30 subjects are improved to different degrees, and the effective rate is 100 percent. The color variation statistics show that the maximum variation value is 67%, the minimum value is 22%, and the average reduction is about 46%. After 8 weeks of comparison of 30 subject control sites, 29 were unchanged from the initial value control, only 1 was slightly changed, and the color chart value decreased by 1.
Example 3
A whitening and repairing cream cosmetic containing the essential oil composition of the invention. The weight percentage of the components is as follows:
essential oil composition of example 1 5%
63.4 percent of rose hydrosol
5 percent of glycerin
3 percent of propylene glycol
Carbomer 0.2%
Olive oil emulsified wax 5.5%
Cetostearyl alcohol 2.5%
Lecithin 1%
Grape seed oil 8%
Jojoba oil 5%
0.5 percent of vitamin E
0.4 percent of phenoxyethanol
0.2 percent of triethanolamine
0.2 percent of essence and pigment
EDTA disodium 0.1%
The preparation method comprises the following steps:
dissolving rose hydrosol, glycerol, propylene glycol, carbomer, phenoxyethanol and EDTA disodium in water in a container 1, continuously stirring until the mixture is uniformly mixed, and heating to 80 ℃; adding oleum Olivarum emulsified wax, cetearyl alcohol, lecithin, jojoba oil, grapeseed oil, and vitamin E into container 2, heating to 80 deg.C, and completely melting. Pouring the materials in the container 2 into the container 1, mixing and homogenizing for 3 minutes to fully emulsify and disperse the two phases, continuously stirring and cooling to 40 ℃, then sequentially adding triethanolamine, essence and pigment and the essential oil composition of the embodiment 1, discharging and filling after completely cooling to room temperature.
Performance experiment 2:
this study investigated the repair of erythema on the subjects after sun exposure by the product of the invention.
Randomly 20 volunteers (subjects) were selected to try the product of example 3. The standard of the test subject is 18-60 years old male or female, the test subject has sunburn within one week, the test part is neck, back or arm with obvious sunburn skin, and the sunburn part has obvious erythema compared with surrounding skin and does not have skin injury symptoms such as desquamation and the like.
The experimental method comprises the following steps: a proper amount of the product of example 3 is applied to part of the erythematous part, and the erythematous part is continuously used for 7 days in the morning and at night respectively, and is compared with nearby erythematous skin without the product of the invention.
The erythema regression, reduction of dryness, and scaling were observed for several aspects and scored by an experienced panel. Score definition: severe sunburn 5 points, severe sunburn 4 points, moderate sunburn 3 points, mild sunburn 2 points, mild sunburn 1 point, and normal skin 0 point.
The experimental results are as follows: when the product of the invention in the example 3 is smeared on a part of sunburned skin, compared with the control group, after 7 days, the average score of the experimental group is 1.6, and the average score of the control group is 4.6. Sunburn was relieved starting the next day after application and was manifested as a 14.3% reduction in erythema and papules, and a 65.2% reduction in erythema and papules after 7 consecutive days. Of the 20 subjects, 11 subjects with severe sunburn and significant peeling in the control area (usually, severe sunburn people generally begin peeling 2-3 days after exposure to the sun and stop peeling 10-15 days later). After 7 days of continuous application of the product, the 11 persons had 7 test areas without peeling, 3 test areas with only slight peeling, and only 1 person had no significant change, compared to the control skin around which the product of the present invention was not applied.
The results show that: the product of the invention in the embodiment 3 is applied after the sun is sunned, the degree of erythema and pimple of the skin after the sun is sunned can be obviously reduced, the effect of relieving the desquamation phenomenon is obvious, and the effect obviously exceeds the self-healing degree of the skin.
Comparative experiment:
in this example, the combination of lavender essential oil, lemon essential oil, tea tree essential oil, geranium essential oil and the four essential oils according to the formulation disclosed in CN105686981A, referred to herein, were used to test the melanin inhibiting effect in comparison to the essential oil composition of example 1 of the present invention (at 5%,20% concentration). The tests were carried out after dilution treatment of 20% by weight of the above essential oils with the cosmetic vehicle exemplified in example 3, and the following were tested:
1. 20 percent of lavender essential oil
2. Lemon essential oil 20%
3. Tea tree essential oil 20%
4. Geranium essential oil 20%
5. The lavender essential oil + the lemon essential oil + the tea tree essential oil + the geranium essential oil compound 20% (CN 105686981A, the weight ratio of the four components is 25
6. Essential oil composition of inventive example 1 5%
7. The essential oil composition of inventive example 1 was 20%
The experimental method adopts an in-vitro whitening test, namely a tyrosinase activity inhibition test. Tyrosinase plays a key role in the biosynthesis of skin melanin, and the amount of melanin production is directly related to tyrosinase activity. Therefore, the intensity of the inhibition effect on tyrosinase can be used as a main index of melanin inhibition rate.
The experimental steps are as follows:
preparing a buffer solution: weighing 7.8g of sodium dihydrogen phosphate and 17.91g of disodium hydrogen phosphate, respectively diluting to 500ml with distilled water, mixing with PBS buffer solution with pH =6.8 and 0.1mol/L,
preparing a tyrosine solution: 0.05g of L-aminobutyric acid was dissolved in 35ml of 0.1mol/L hydrochloric acid solution, and 65ml of the above buffer solution was added to obtain a 0.05% tyrosine solution.
Preparing a tyrosinase solution: dissolving tyrosinase with enzyme activity of 25000U in 250ml distilled water to obtain solution with enzyme activity of 100U/ml
And (4) subpackaging the tyrosinase solution into test tubes.
Tyrosinase activity assay: and (3) adding the test sample (1 g) into a tyrosine solution, carrying out water bath at 37 ℃ for 10 minutes, then respectively adding tyrosinase into each test object, fully shaking up, accurately timing the reaction for 15 minutes, stopping the reaction, and measuring the absorbance at 475nm by using an enzyme-linked immunosorbent assay. And the inhibition rate was calculated.
The same procedure as above was carried out with PBS buffer instead of test sample as negative control, with results: the tyrosinase inhibition rates of the above 7 experimental groups were respectively: 1.4% of lavender, 4.7% of lemon, 8.2% of tea tree, 11.3% of geranium, and 23.5% of a lavender + lemon + tea tree + geranium compound; the inhibition rate of the composition of the invention at 5% concentration is 78.2%, and the inhibition rate at 20% concentration is 92.1%.
And (4) conclusion: the essential oil composition has a synergistic effect on melanin inhibition, and the effect of the essential oil composition is obviously superior to that of the essential oil composition in the prior art.
Claims (10)
1. An essential oil composition for whitening or after-sun repair comprises the following six components in percentage by weight:
lavender essential oil: 30 to 38 percent
Lemon essential oil: 16-23 percent
Tea tree essential oil: 14 to 22 percent
Geranium essential oil: 10-16 percent
Roman chamomile essential oil: 5 to 13 percent of
Carrot seed oil: 4 to 8 percent.
2. The essential oil composition of claim 1, wherein the essential oil composition comprises the following six components in weight percent:
lavender essential oil: 34 to 36 percent
Lemon essential oil: 19 to 21 percent
Tea tree essential oil: 17 to 19 percent
Geranium essential oil: 12 to 14 percent
Roman chamomile essential oil: 8 to 10 percent of
Carrot seed oil: 5 to 7 percent.
3. The essential oil composition of claim 1, wherein the essential oil composition comprises the following six components in weight percent:
34.5 percent of lavender essential oil
Lemon essential oil: 19.5 percent
Tea tree essential oil: 18 percent
Geranium essential oil: 13 percent of
Roman chamomile essential oil: 9 percent of
Carrot seed oil: 6 percent.
4. The essential oil composition of any one of claims 1-3 wherein the essential oil composition consists of the six components.
5. A cosmetic for whitening or after-sun repair comprising the essential oil composition of any one of claims 1 to 4 in an amount of from more than 0% to 30% by weight, and a cosmetically acceptable carrier therefor.
6. The cosmetic as set forth in claim 5, wherein the content of the essential oil composition is 1 to 20% by weight.
7. The cosmetic as set forth in claim 5, wherein the content of the essential oil composition is 2 to 6% by weight.
8. The cosmetic as claimed in claim 5, wherein the cosmetically acceptable carrier is of a water-oil emulsified type or a pure oil type.
9. A method for preparing an essential oil composition, wherein the components of the essential oil composition as claimed in any of claims 1 to 4 are added in portions or simultaneously in a container and mixed or stirred at room temperature until homogeneous.
10. A process for the preparation of a cosmetic product, wherein cosmetically acceptable carrier components are mixed and dissolved in portions or simultaneously in one or more containers, and the essential oil composition according to any one of claims 1 to 4 is added to the obtained carrier in an amount of from more than 0% to less than or equal to 30% by weight.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202210979033.XA CN115252481B (en) | 2022-08-16 | 2022-08-16 | Repairing and whitening essential oil composition and preparation method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202210979033.XA CN115252481B (en) | 2022-08-16 | 2022-08-16 | Repairing and whitening essential oil composition and preparation method thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN115252481A true CN115252481A (en) | 2022-11-01 |
| CN115252481B CN115252481B (en) | 2024-02-09 |
Family
ID=83751418
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202210979033.XA Active CN115252481B (en) | 2022-08-16 | 2022-08-16 | Repairing and whitening essential oil composition and preparation method thereof |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN115252481B (en) |
Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103263369A (en) * | 2013-05-20 | 2013-08-28 | 赵丽 | Compound essential oil for improving seasoning crack of face skin |
| CN103385813A (en) * | 2012-05-11 | 2013-11-13 | 苏州纳特苏生物科技有限公司 | Compound essential oil for cleaning, refreshing and back beautifying |
| CN104161705A (en) * | 2014-08-21 | 2014-11-26 | 青岛蓝图文化传播有限公司市南分公司 | Anti-dandruff compound essential oil |
| CN105640809A (en) * | 2014-11-10 | 2016-06-08 | 闫战军 | Nourishing oil containing tea tree essential oil and aloe oil and capable of repairing pimples and acnes and preparation method of nourishing oil |
| CN105686981A (en) * | 2014-11-25 | 2016-06-22 | 郭亚萍 | Acne removing and whitening essential oil |
| CN106619215A (en) * | 2016-10-20 | 2017-05-10 | 岳俊洪 | Plant essential oil composition with efficacies of moisturizing and soothing skin and preparation of plant essential oil composition |
-
2022
- 2022-08-16 CN CN202210979033.XA patent/CN115252481B/en active Active
Patent Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103385813A (en) * | 2012-05-11 | 2013-11-13 | 苏州纳特苏生物科技有限公司 | Compound essential oil for cleaning, refreshing and back beautifying |
| CN103263369A (en) * | 2013-05-20 | 2013-08-28 | 赵丽 | Compound essential oil for improving seasoning crack of face skin |
| CN104161705A (en) * | 2014-08-21 | 2014-11-26 | 青岛蓝图文化传播有限公司市南分公司 | Anti-dandruff compound essential oil |
| CN105640809A (en) * | 2014-11-10 | 2016-06-08 | 闫战军 | Nourishing oil containing tea tree essential oil and aloe oil and capable of repairing pimples and acnes and preparation method of nourishing oil |
| CN105686981A (en) * | 2014-11-25 | 2016-06-22 | 郭亚萍 | Acne removing and whitening essential oil |
| CN106619215A (en) * | 2016-10-20 | 2017-05-10 | 岳俊洪 | Plant essential oil composition with efficacies of moisturizing and soothing skin and preparation of plant essential oil composition |
Also Published As
| Publication number | Publication date |
|---|---|
| CN115252481B (en) | 2024-02-09 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| US20050100524A1 (en) | Skin formulation | |
| EP2323969B1 (en) | Use of esters derived from natural sources having lower viscosity and higher spread rate as well as preparation of natural personal care composition comprising such esters | |
| CN111297745A (en) | Absorption-promoting whitening composition and production process and application thereof | |
| US7223423B2 (en) | Skin treatment composition | |
| JP3513872B2 (en) | External preparation for skin | |
| JPH11315008A (en) | Antiaging agent | |
| JP3544609B2 (en) | Anti-aging agent | |
| JPS5811922B2 (en) | Keshiyouriyo | |
| JPH1029927A (en) | Antiaging agent | |
| CN115252481A (en) | Repairing and whitening essential oil composition and preparation method thereof | |
| CN110917105A (en) | Allergy-relieving cosmetic composition and preparation method thereof | |
| US4816271A (en) | Skin lotions and creams | |
| JPH11246337A (en) | Antiaging agent | |
| JPH1179970A (en) | Collagenase inhibitor | |
| JP5000964B2 (en) | Testosterone 5α-reductase activity inhibitor, androgen receptor antagonist, use thereof, and method for suppressing androgen activity expression | |
| WO1998041183A1 (en) | Dermatologic preparations for beautifying | |
| CN107753582B (en) | Composition for treating acne, external gel and preparation method thereof | |
| JP3270219B2 (en) | External preparation for skin | |
| JPH11246385A (en) | Antiaging agent | |
| JP2992510B1 (en) | Hair restoration | |
| JP2000154132A (en) | Antiaging agent | |
| JP2982872B1 (en) | External preparation for slimming skin | |
| CN108938522B (en) | Makeup removing lotion containing PEG-12 monolaurate and preparation method thereof | |
| DĂNILĂ et al. | Obtaining and characterization of some emulsions based on collagen hydrolysate and natural extracts with a potential anticellulitic action | |
| JPH0517202B2 (en) |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| GR01 | Patent grant | ||
| GR01 | Patent grant |