CN115227621A

CN115227621A - Whitening composition, application thereof and cream and milk containing composition

Info

Publication number: CN115227621A
Application number: CN202210875159.2A
Authority: CN
Inventors: 高德爱; 殷运华
Original assignee: Guangzhou Shouyang Pharmaceutical Biotechnology Co ltd; Guangzhou Xilisha Biotechnology Co ltd; Weiyimei Biotechnology Guangzhou Co ltd
Current assignee: Guangzhou Shouyang Pharmaceutical Biotechnology Co ltd; Guangzhou Xilisha Biotechnology Co ltd; Weiyimei Biotechnology Guangzhou Co ltd
Priority date: 2022-07-25
Filing date: 2022-07-25
Publication date: 2022-10-25

Abstract

The invention relates to the field of skin care products, and particularly discloses a whitening composition, application thereof and cream and milk containing the composition. The whitening composition comprises the following components in parts by mass: 1.497-1.521 parts of solvent; birch bark extract 3.955-3.957 parts; 0.043-0.045 parts of a root extract of the comfrey; 0.014-0.016 part of cinnamomum japonicum rhizome extract; 0.0074-0.0076 parts of Ningxia wolfberry fruit extract; 0.014-0.016 part of kushen root extract; 0.0074-0.0076 parts of pyracantha fortuneana fruit extract; 0.575 to 0.577 parts of mulberry root bark extract; 0.551-8978 parts of raspberry fruit extract of 8978 zxft; 0.017-0.019 parts of centella asiatica extract. The invention has the advantage of improving the durability of the whitening effect.

Description

Whitening composition, application thereof and cream and milk containing composition

Technical Field

The invention relates to the field of skin care products, in particular to a whitening composition, application thereof and cream and milk containing the composition.

Background

Melanin is produced by melanocytes and then transferred to surrounding keratinocytes, and melanin stays on the nuclei of the keratinocytes to protect them from damage caused by light irradiation, but the excessive melanin darkens the skin and affects the beauty.

Therefore, whitening skin is an important branch of skin care, people prefer white skin based on modern pursuit of beauty, and the more white the skin, the more aesthetic the skin can be embodied, so that the skin care product with the whitening effect is deeply loved by people.

The existing whitening skin care product is mainly realized by three means of inhibiting the activity of tyrosinase, blocking the transfer of melanin and accelerating metabolism, the generation of melanin can be reduced by inhibiting the activity of tyrosinase, and the skin color of the skin is not easy to darken by reducing the generation of melanin, so that the whitening effect is realized.

However, when a substance inhibiting tyrosinase activity is metabolized, tyrosinase activity is restored, resulting in darkening of skin color again, and the whitening effect is generally persistent, and thus it is generally required to be used for a long time, and severe tolerance is generated, thus there is room for improvement.

Disclosure of Invention

In order to improve the durability of whitening effect, the application provides a whitening composition, application thereof and cream and milk containing the composition.

In a first aspect, the present application provides a whitening composition, which adopts the following technical scheme:

the whitening composition comprises the following components in parts by mass:

1.497 to 1.521 parts of solvent;

birch bark extract 3.955-3.957 parts;

0.043-0.045 parts of a root extract of the comfrey;

0.014-0.016 part of cinnamomum japonicum rhizome extract;

0.0074-0.0076 parts of Ningxia wolfberry fruit extract;

0.014-0.016 part of kuh-seng root extract;

0.0074-0.0076 part of pyracantha fortuneana fruit extract;

0.575 to 0.577 parts of mulberry root bark extract;

0.551-8978 parts of raspberry fruit extract with the weight of 8978 zxft;

0.017 to 0.019 portion of asiatic pennywort herb extract.

By adopting the technical scheme, the active ingredients of the composition are absorbed by the skin through compounding of the birch bark extract, the comfrey root extract, the cinnamomum cassia twig root extract, the lycium barbarum fruit extract, the picrasma kurroa root extract, the pyracantha fortuneana fruit extract, the mulberry root bark extract, the raspberry fruit extract and the centella asiatica extract, the tyrosinase in the skin can be completely inactivated, the concentration of the tyrosinase in the skin is reduced along with metabolic discharge, the generation amount of the melanin is greatly reduced, the generation of the melanin is reduced from the root, the accumulation of the melanin in the skin is reduced, and the skin is white.

The composition can also inhibit mitosis of keratinocyte and melanocyte, has good effect in removing mottle, and can accelerate melanin metabolism and discharge melanin, so as to make skin quickly recover to be white.

The composition can completely inactivate tyrosinase, so that after active ingredients are metabolized and discharged, the activity of the tyrosinase can not be quickly recovered, and the tyrosinase can be accumulated again only through in vivo synthesis, so that the whitening skin care product added with the composition can be stopped from using after being used for a period of time until the skin becomes white, the skin can not be quickly recovered to be dull due to stopping using, the whitening effect is better in durability, the dependence on the whitening skin care product is reduced, the conventional moisturizing skin care product can be replaced after whitening, the skin can be kept white for a long time only by regularly using the whitening skin care product, the phenomenon that a skin protection layer becomes thin due to long-term use of the whitening skin care product is reduced, the skin is white and is not easy to become fragile, the skin can better resist external erosion, and the skin is not easy to be damaged.

Preferably, the feed also comprises the following components in parts by mass:

1.48-1.52 parts of 3-o-ethyl ascorbic acid.

By adopting the technical scheme, the 3-o-ethyl ascorbic acid is added to accelerate the metabolism of the horny layer, so that the dull horny layer falls off to expose the new fair skin, and the whitening effect is quick.

Preferably, the solvent is a compound of water, butanediol and p-hydroxyacetophenone.

By adopting the technical scheme, the components are easier to dissolve and are uniformly dispersed by compounding the water, the butanediol and the p-hydroxyacetophenone, so that the effect of mutually matching the components is better, the effect of completely inactivating the tyrosinase is better played, and the whitening effect is more durable.

Preferably, the mass ratio of the water to the butanediol to the p-hydroxyacetophenone is 0.854-0.856:0.59-0.61:0.053-0.055.

By adopting the technical scheme, the ratio of water, butanediol and p-hydroxyacetophenone is specifically selected, so that the effect of dissolving the components is better, and the quality of the prepared whitening composition is better.

In a second aspect, the present application provides a whitening cream, which adopts the following technical scheme:

the whitening cream comprises the following components in parts by weight:

54.3656-55.5344 parts of solvent;

8.02-8.08 parts of a humectant;

9.94-10.06 parts of an emollient;

4.9-5 parts of a skin conditioner;

9.18 to 9.42 portions of emulsifier;

1.18-1.22 parts of antioxidant;

0.697-0.703 part of thickening agent;

film forming agent 1.0898-1.1102 parts;

0.49-0.51 part of penetration enhancer;

preservative 0.7788-0.8212 parts;

0.19-0.21 part of chelating agent;

8-8.5 parts of a whitening composition;

the whitening composition is the whitening composition.

By adopting the technical scheme, the whitening cream has a good whitening effect, is lasting in whitening effect, does not need to be used for a long time, can be replaced with a common moisturizing skin care product, can greatly reduce the use frequency of the whitening cream after the whitening is carried out for the first time, enables the skin to be white and is not easy to become fragile due to the thinning of the cuticle, and accordingly enables the skin to be not easy to damage and keeps the skin healthy.

In a third aspect, the application provides a whitening cream, which adopts the following technical scheme:

the whitening milk comprises the following components in parts by mass:

73.8648-74.7552 parts of solvent;

3.99 to 4.05 parts of humectant;

5.94-6.06 parts of an emollient;

2.97-3.03 parts of a skin conditioner;

2.47-2.53 parts of an emulsifier;

0.29-0.31 part of antioxidant;

0.416 to 0.424 portion of thickening agent;

0.39-0.41 part of penetration enhancer;

preservative 0.7788-0.8212 parts;

8-8.5 parts of a whitening composition;

the whitening composition is the whitening composition.

By adopting the technical scheme, the whitening milk has a good whitening effect, the whitening effect has good durability, the whitening milk does not need to be continuously used after whitening, a common moisturizing skin care product can be better, the damage of the skin cuticle caused by long-term use of the whitening milk is reduced, and the skin is healthier.

In a fourth aspect, the present application provides an application of a whitening composition, which adopts the following technical scheme:

the application of the whitening composition is that the whitening composition is added into a skin care product.

By adopting the technical scheme, the whitening composition is added into the skin care product, so that the skin care product has a good whitening effect and a good lasting whitening effect, the use frequency of the whitening skin care product is reduced, and the skin is healthier.

Preferably, the addition amount of the whitening composition is 8-8.5% of the total mass of the skin care product.

By adopting the technical scheme, the content of the whitening composition in the skin care product is specifically selected, so that the skin care product has a good whitening effect, takes effect quickly, reduces the damage to the skin, controls the cost, has higher economic value and is easy to popularize.

In summary, the present application has the following beneficial effects:

1. according to the whitening skin care product, the compound of the birch bark extract, the comfrey root extract, the cinnamomum cassia root extract, the lycium barbarum fruit extract, the picrashiza kurroa root extract, the pyracantha fortuneana fruit extract, the mulberry root bark extract, the raspberry fruit extract and the centella asiatica extract is adopted, so that tyrosinase is completely inactivated, after active ingredients are metabolized and discharged, the activity of tyrosinase cannot be quickly recovered, tyrosinase can be accumulated again through in vivo synthesis, the whitening skin care product added with the composition can be stopped to be used after the skin is whitened after being used for a period of time, the skin cannot be quickly restored to darkness due to stopping use, the durability of the whitening effect is good, the dependence on the whitening skin care product is reduced, the conventional moisturizing skin care product can be replaced after whitening, the skin can be kept white for a long time only by regularly using the whitening skin care product, the phenomenon that a skin protection layer is thinned due to long-term use of the whitening skin care product is reduced, the skin is not easy to be fragile while the skin is white, and the skin can better resist external erosion and is not easy to be damaged.

2. In the application, 3-o-ethyl ascorbic acid is preferably added to accelerate stratum corneum metabolism, so that a dull stratum corneum falls off and a new fair skin is exposed, and the whitening effect is quick.

3. In the application, the components are easier to dissolve by compounding the water, the butanediol and the p-hydroxyacetophenone, so that the components are uniformly dispersed, the effect of mutually matching the components is better, the effect of completely inactivating the tyrosinase is better played, and the whitening effect is more durable.

Detailed Description

The present application will be described in further detail with reference to examples.

Example 1

A whitening composition consists of the following components:

solvent, birch bark extract, comfrey root extract, cinnamomum japonicum rhizome extract, fructus lycii ninghamii extract, sophora flavescens root extract, pyracantha fortuneana fruit extract, mulberry root bark extract, raspberry fruit extract, centella asiatica extract and 3-o-ethyl ascorbic acid.

Wherein the solvent is a compound of water, butanediol and p-hydroxyacetophenone.

The birch bark extract and the rhizoctonia solani root extract are purchased from British chemical industry Co., ltd of Bo of Guangzhou, and are extracted by water according to the proportion of 10:1.

the extract of the rhizome of the phyllostachys edulis and the extract of the fruit of the Lycium barbarum are purchased from Shanghai Jia Kai Biotech limited company, and are extracted by water according to the proportion of 10:1.

the extract of the kushen root is purchased from xi' an Shen agricultural biotechnology limited company, and is extracted by water, and the proportion of the extract is 10:1.

the pyracantha fortuneana fruit extract is purchased from Xian Youchuo Biotech Co., ltd, and is extracted by water, and the proportion of the extract is 10:1.

the mulberry root bark extract and the raspberry fruit extract are purchased from Guangzhou Galneng biotechnology limited, and are extracted by water according to the proportion of 10:1.

the centella asiatica extract is purchased from Shanxi Yang biomedical science and technology limited, and is extracted by water in a proportion of 10:1.

the preparation method of the whitening composition comprises the following steps:

step 1), 0.854kg of water, 0.59kg of butanediol, 0.053kg of p-hydroxyacetophenone and 1.48kg of 3-o-ethyl ascorbic acid are put into a stirring kettle and stirred for 3min at the rotating speed of 120r/min to obtain a premix.

Step 2), putting 3.955kg of birch bark extract, 0.043kg of comfrey root extract, 0.014kg of cinnamomum cassia twig rhizome extract, 0.0074kg of Ningxia wolfberry fruit extract, 0.014kg of sophora flavescens root extract, 0.0074kg of pyracantha fortuneana fruit extract, 0.575kg of mulberry root bark extract, 0.551kg of raspberry fruit extract and 0.017kg of centella asiatica extract into the premix, heating to 40 ℃, keeping the temperature at the rotating speed of 120r/min, and stirring for 10min to obtain the whitening composition.

Example 2

A whitening composition consists of the following components:

solvent, birch bark extract, comfrey root extract, cinnamomum cassia rhizome extract, fructus lycii ninghamii extract, sophora flavescens root extract, pyracantha fortuneana fruit extract, mulberry root bark extract, raspberry fruit extract, centella asiatica extract and 3-o-ethyl ascorbic acid.

the mangosteen rhizome extract and the Ningxia wolfberry fruit extract are purchased from Shanghai Gaojia Kai Biotechnology limited company, and are extracted by water, and the proportion of the extracts is 10:1.

the mulberry root bark extract and the raspberry fruit extract are purchased from Guangzhou Galen biological technology limited company, and are extracted by water according to the proportion of 10:1.

step 1), putting 0.855kg of water, 0.6kg of butanediol, 0.054kg of p-hydroxyacetophenone and 1.5kg of 3-o-ethyl ascorbic acid into a stirring kettle, and stirring at the rotating speed of 120r/min for 3min to obtain a premix.

Step 2), putting 3.956kg of birch bark extract, 0.044kg of comfrey root extract, 0.015kg of cinnamomum cassia twig rhizome extract, 0.0075kg of Ningxia wolfberry fruit extract, 0.015kg of sophora flavescens root extract, 0.0075kg of pyracantha fortuneana fruit extract, 0.576kg of mulberry root bark extract, 0.552kg of raspberry fruit extract and 0.018kg of centella asiatica extract into a premix, heating to 40 ℃, keeping the temperature at the constant speed of 120r/min, and stirring for 10min to obtain the whitening composition.

Example 3

A whitening composition consists of the following components:

centella asiatica extract is purchased from Shanxi Angsheng biological medicine science and technology limited company, and is extracted by water, the proportion of the extract is 10:1.

step 1), 0.856kg of water, 0.61kg of butanediol, 0.055kg of p-hydroxyacetophenone and 1.52kg of 3-o-ethyl ascorbic acid are put into a stirring kettle, the rotating speed is 120r/min, and the stirring is carried out for 3min, so as to obtain the premix.

Step 2), putting 3.957kg of white birch bark extract, 0.045kg of comfrey root extract, 0.016kg of cinnamomum cassia rhizome extract, 0.0076kg of ningxia wolfberry fruit extract, 0.016kg of kuh-seng root extract, 0.0076kg of pyracantha fortuneana fruit extract, 0.577kg of mulberry root bark extract, 0.553kg of raspberry fruit extract and 0.019kg of centella asiatica extract into the premix, heating to 40 ℃, keeping the temperature, rotating at 120r/min, and stirring for 10min to obtain the whitening composition.

Application examples 1 to 3

A whitening cream comprises the following components:

solvents, humectants, emollients, skin conditioners, emulsifiers, antioxidants, thickeners, film formers, penetration enhancers, preservatives, chelating agents, and whitening compositions.

Wherein the solvent is water.

The humectant is prepared by compounding glyceryl polyether-26 and sodium hyaluronate.

The emollient is the compound of ethylhexyl palmitate, polydimethylsiloxane and caprylic/capric triglyceride.

The skin conditioner is a compound of nicotinamide, carnosine and allantoin.

The emulsifier is compound of cetostearyl alcohol, white beeswax, steareth-2, steareth-21, glyceryl stearate and PEG-100 stearate.

The antioxidant is tocopherol acetate.

The thickening agent is a compound of sodium polyacrylate, ethylhexyl stearate and tridecyl alcohol polyether-6.

The film forming agent is ethylhexyl methoxycinnamate, butylated hydroxytoluene and polyacrylate cross-linked polymer-6.

The penetration enhancer is laurocapram.

The preservative is phenoxyethanol, 1,2-hexanediol, chlorphenesin, methylparaben and propylparaben, and the chelating agent is EDTA disodium.

The whitening composition of application example 1 was the whitening composition of example 1, the whitening composition of application example 2 was the whitening composition of example 2, and the whitening composition of application example 3 was the whitening composition of example 3.

In application examples 1-3, the specific amounts (in kg) of each component added are detailed in Table 1.

TABLE 1

In application examples 1 to 3, the preparation method of the whitening cream is as follows:

step 01), putting water, glyceryl polyether-26, polyacrylate cross-linked polymer-6, allantoin, EDTA disodium, methylparaben and sodium hyaluronate into an emulsifying pot, stirring for 3min at a rotation speed of 120r/min, heating to 85 ℃, and preserving heat for 20min to obtain phase A.

Step 02), putting ethylhexyl palmitate, nicotinamide, polydimethylsiloxane, caprylic/capric triglyceride, cetostearyl alcohol, white beeswax, steareth-2, steareth-21, glyceryl stearate, PEG-100 stearate, tocopheryl acetate, ethylhexyl methoxycinnamate, butylated hydroxytoluene, laurocapram and propyl hydroxybenzoate into an oil pan, stirring for 3min at a rotation speed of 120r/min, heating to 85 ℃, and keeping the temperature for 20min to obtain a phase B.

And 03), mixing the phase A and the phase B, homogenizing for 5min at 0.01MPa at 2400r/min, and then preserving the temperature for 25min at 85 ℃ to obtain a premix.

And 04) cooling the premix to 70 ℃, adding sodium polyacrylate, ethylhexyl stearate and tridecyl alcohol polyether-6, and homogenizing for 4min at 2400r/min under 0.01MPa to obtain a mixture.

And step 05), cooling the mixture to 40 ℃, adding carnosine, phenoxyethanol, 1,2-hexanediol, chlorphenesin and the whitening composition, rotating at the speed of 120r/min, stirring for 10min, and discharging to obtain the whitening cream.

Application examples 4 to 6

A whitening milk comprises the following components:

solvent, humectant, emollient, skin conditioner, emulsifier, antioxidant, thickener, penetration enhancer, antiseptic, and whitening composition.

Wherein the solvent is water.

The humectant is prepared by compounding glycerol and sodium hyaluronate.

The emollient is a compound of ethylhexyl palmitate, polydimethylsiloxane and caprylic/capric triglyceride.

The skin conditioner is a compound of nicotinamide and carnosine.

The emulsifier is compound of cetostearyl alcohol, glycerol stearate and PEG-100 stearate.

The antioxidant is tocopherol acetate.

The thickening agent is a compound of sodium acrylate/acryloyl dimethyl sodium taurate copolymer, isohexadecane, polysorbate-80 and sorbitan oleate.

The penetration enhancer is laurocapram.

The preservative is a compound of phenoxyethanol, 1,2-hexanediol, chlorphenesin, methylparaben and propylparaben.

The whitening composition of application example 4 was the whitening composition of example 1, the whitening composition of application example 5 was the whitening composition of example 2, and the whitening composition of application example 6 was the whitening composition of example 3.

The specific amounts (in kg) of the components used in application examples 4-6 are detailed in Table 2.

TABLE 2

In application examples 4-6, the whitening milk is prepared as follows:

step 001), putting water, glycerol, nicotinamide, methyl hydroxybenzoate and sodium hyaluronate into an emulsifying pot, stirring for 3min at a rotation speed of 120r/min, heating to 85 ℃, and preserving heat for 20min to obtain phase A.

And (002), putting ethylhexyl palmitate, polydimethylsiloxane, caprylic/capric triglyceride, cetostearyl alcohol, glyceryl stearate, PEG-100 stearate, tocopheryl acetate, laurocapram and propyl hydroxybenzoate into an oil pan, stirring for 3min at the rotating speed of 120r/min, heating to 85 ℃, and preserving heat for 20min to obtain a phase B.

And step 003), mixing the phase A and the phase B, homogenizing for 5min at the pressure of 0.01MPa and the pressure of 2400r/min, and then preserving the heat for 25min at the temperature of 85 ℃ to obtain a premix.

And 004) cooling the premix to 70 ℃, adding sodium acrylate/acryloyl dimethyl sodium taurate copolymer, isohexadecane, polysorbate-80 and sorbitan oleate, homogenizing for 4min at 2400r/min under 0.01MPa to obtain a mixture.

And 005) cooling the mixture to 40 ℃, adding carnosine, phenoxyethanol, 1,2-hexanediol, chlorphenesin and the whitening composition, stirring at the rotation speed of 120r/min for 10min, and discharging to obtain the whitening emulsion.

Comparative example 1

A whitening composition, differing from example 2 only in that:

equal amount of the birch bark extract was replaced by corn extract.

The corn extract is obtained from commercial sources by water extraction, and the ratio of the extract 10:1.

comparative example 2

A whitening composition, differing from example 2 only in that:

the extract of the root of the honewort is replaced by the extract of the root of the peony with equal quantity.

The peony root extract is obtained from the market and is extracted by water, and the ratio of the extract is 10:1.

comparative example 3

A whitening composition, differing from example 2 only in that:

equal amount of ginseng root extract is adopted to replace the extract of the root and stem of the phyllostachys pubescens.

The ginseng root extract is obtained from the market and is extracted by water, and the ratio of the extract 10:1.

comparative example 4

A whitening composition, differing from example 2 only in that:

the extract of the fructus lycii of Ningxia wolfberry fruit is replaced by the extract of the ginkgo root in the same amount.

The ginkgo root extract is obtained from the market and is extracted by water, and the ratio of the extract is 10:1.

comparative example 5

A whitening composition, differing from example 2 only in that:

the extract of the root of the Sophora flavescens ait is replaced by the extract of the grape seeds with equal quantity.

The grape seed extract is obtained from the market and is extracted by water, and the ratio of the extract 10:1.

comparative example 6

A whitening composition, differing from example 2 only in that:

equal amount of peach flower extract is used to replace pyracantha fortuneana fruit extract.

The peach blossom extract is obtained from the market and is extracted by water, and the ratio of the extract 10:1.

comparative example 7

A whitening composition, differing from example 2 only in that:

the extract of the mulberry root bark is replaced by the extract of the pomegranate fruit in equal amount.

The pomegranate fruit extract is obtained from the market by water extraction, and the ratio of the extract is 10:1.

comparative example 8

A whitening composition, differing from example 2 only in that:

replacing raspberry fruit extract with Salvia officinalis extract in equal amount.

The sage extract is obtained from the market and is extracted by water, and the ratio of the extract 10:1.

comparative example 9

A whitening composition, differing from example 2 only in that:

the extract of centella asiatica is replaced by the extract of angelica dahurica root in equal amount.

The angelica dahurica root extract is obtained from the market and is extracted by water, and the proportion of the extract is 10:1.

comparative application example 1

Compared with application example 2, the difference is only that:

the whitening composition was the whitening composition of comparative example 1.

Comparative application example 2

Compared with application example 2, the difference is only that:

the whitening composition was the whitening composition of comparative example 2.

Comparative application example 3

Compared with application example 2, the difference is only that:

the whitening composition was the whitening composition of comparative example 3.

Comparative application example 4

Compared with application example 2, the difference is only that:

the whitening composition was the whitening composition of comparative example 4.

Comparative application example 5

Compared with application example 2, the differences are only that:

the whitening composition was the whitening composition of comparative example 5.

Comparative application example 6

Compared with application example 2, the difference is only that:

the whitening composition was the whitening composition of comparative example 6.

Comparative application example 7

Compared with application example 2, the differences are only that:

the whitening composition was the whitening composition of comparative example 7.

Comparative application example 8

Compared with application example 2, the difference is only that:

the whitening composition was the whitening composition of comparative example 8.

Comparative application example 9

Compared with application example 2, the difference is only that:

the whitening composition was the whitening composition of comparative example 9.

Experiment 1

The tyrosinase inhibition rates of the whitening compositions of the examples and the comparative examples were tested according to T/GDCA 006-2021 "test method for tyrosinase activity inhibition by cosmetic raw materials (in vitro method)". The sample concentrations were 0.313%, 0.625%, 1.25%, 2.5%, 5%, respectively. The control group was 0.3% kojic acid, and the tyrosinase inhibition rate of the control group was 53.15%.

Experiment 2

The method comprises the steps of collecting a plurality of volunteers, wherein the volunteers are 40-45 years old, women are in a group of every 5 persons, the whitening cream or the whitening milk of each application example and the comparative application example is respectively used once in the morning and at night and for 28 days, before the use, the skin melanin content is detected to be used as the initial melanin content, after the use for 28 days, the skin melanin content is detected again to obtain the melanin content after whitening, then the whitening cream or the whitening milk is stopped, and after the use for 28 days, the skin melanin content is detected by love to obtain the melanin content after the stop.

And dividing the difference value of the initial melanin content and the melanin content after whitening by the initial melanin content to obtain the melanin reduction rate after whitening.

The melanin reduction rate after the disuse is obtained by dividing the difference between the initial melanin content and the melanin content after the disuse by the initial melanin content.

The specific detection data of experiments 1 and 2 are detailed in tables 3 and 4.

TABLE 3

TABLE 4

According to the comparison of the data in tables 3 and 4, the whitening composition has a good tyrosinase activity inhibiting effect when the birch bark extract, the comfrey root extract, the cinnamomum cassia twig root extract, the fructus lycii ninghamii extract, the sophora flavescens root extract, the pyracantha fortunei fruit extract, the mulberry root bark extract, the raspberry fruit extract and the centella asiatica extract are compounded, and the content of melanin in the skin can be obviously reduced after the whitening cream or the whitening emulsion added with the whitening composition is used.

When any one of the components of the white birch bark extract, the comfrey root extract, the cinnamomum japonicum rhizome extract, the fructus lycii ningpoensis extract, the picrashiza kurroa root extract, the pyracantha fortuneana fruit extract, the mulberry root bark extract, the raspberry fruit extract and the centella asiatica extract is replaced by a combination with similar effects in an equal amount, the effect of inhibiting the tyrosinase activity fluctuates to a small extent, but the decrease rate of the melanin content is greatly reduced after the skin is stopped for 28 days, so that although the white birch bark extract, the comfrey root extract, the comfrey fruit extract, the picrashiza kurroa root extract, the pyracantha fortis stopped, the tyrosinase activity inhibiting effect can be obtained well after the skin is stopped for 28 days, the inhibition belongs to restorable inhibition, the restorability inhibition is recovered, the tyrosinase activity is accelerated, and the skin is quickly whitened without the tyrosinase inhibiting activity of the cortex lycii ningpoensis extract after the active components are reduced or even disappear due to skin metabolism of the skin is stopped, the skin is quickly recovered, the tyrosinase inhibiting activity of the skin is maintained, and the tyrosinase inhibiting the tyrosinase activity of the skin is quickly recovered, the skin is not easily after the skin is quickly recovered, the skin is quickly, the skin is deactivated after the skin is stopped for a long time, the skin is recovered, the skin is quickly, the skin is whitened, and the skin is protected, the tyrosinase inhibiting effect is maintained, and the skin is not easily, the skin is quickly whitened, the tyrosinase inhibiting effect is maintained, the skin is not easily, the skin is quickly, and the skin is not easily recovered, the corrosion of acid substances in the whitening skin care product to the skin cuticle is reduced, so that the whitening skin care product can be used at intervals with a common moisturizing skin care product after the whitening skin care product is firstly used, the use frequency of the whitening skin care product can be low, a better protection system is kept while the skin is white, the skin is healthier and better plays a role in protection, and the skin is not easy to damage.

The present embodiment is only for explaining the present application, and it is not limited to the present application, and those skilled in the art can make modifications of the present embodiment without inventive contribution as needed after reading the present specification, but all of them are protected by patent law within the scope of the claims of the present application.

Claims

1. A whitening composition characterized by: the paint comprises the following components in parts by mass:

1.497-1.521 parts of solvent;

birch bark extract 3.955-3.957 parts;

0.043-0.045 parts of a root extract of the comfrey;

0.014-0.016 part of cinnamomum japonicum rhizome extract;

0.0074-0.0076 parts of Ningxia wolfberry fruit extract;

0.014-0.016 part of kushen root extract;

0.0074-0.0076 parts of pyracantha fortuneana fruit extract;

0.575 to 0.577 parts of mulberry root bark extract;

0.551-8978 parts of raspberry fruit extract of 8978 zxft;

0.017-0.019 parts of centella asiatica extract.

2. The whitening composition of claim 1, wherein: the paint also comprises the following components in parts by mass:

1.48-1.52 parts of 3-o-ethyl ascorbic acid.

3. The whitening composition according to claim 1, characterized in that: the solvent is a compound of water, butanediol and p-hydroxyacetophenone.

4. A whitening composition according to claim 3, characterized in that: the mass ratio of the water to the butanediol to the p-hydroxyacetophenone is 0.854-0.856:0.59-0.61:0.053-0.055.

5. The whitening cream is characterized in that: the paint comprises the following components in parts by mass:

54.3656-55.5344 parts of solvent;

8.02-8.08 parts of a humectant;

9.94-10.06 parts of an emollient;

4.9-5 parts of a skin conditioner;

9.18-9.42 parts of an emulsifier;

1.18-1.22 parts of antioxidant;

0.697 to 0.703 portion of thickening agent;

film forming agent 1.0898-1.1102 parts;

0.49-0.51 part of penetration enhancer;

preservative 0.7788-0.8212 parts;

0.19-0.21 part of chelating agent;

8-8.5 parts of a whitening composition;

the whitening composition according to any one of claims 1 to 4.

6. A whitening milk is characterized in that: the paint comprises the following components in parts by mass:

73.8648-74.7552 parts of solvent;

3.99-4.05 parts of a humectant;

5.94-6.06 parts of an emollient;

2.97-3.03 parts of a skin conditioner;

2.47-2.53 parts of an emulsifier;

0.29-0.31 part of antioxidant;

0.416-0.424 parts of thickening agent;

0.39-0.41 part of penetration enhancer;

preservative 0.7788-0.8212 parts;

8-8.5 parts of a whitening composition;

the whitening composition according to any one of claims 1 to 4.

7. Use of a whitening composition according to any one of claims 1 to 4, characterized in that: the whitening composition is added into a skin care product.

8. Use of a whitening composition according to claim 7, characterized in that: the addition amount of the whitening composition is 8-8.5% of the total mass of the skin care product.