CN115151272A - 嵌合抗原受体的优化 - Google Patents
嵌合抗原受体的优化 Download PDFInfo
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- CN115151272A CN115151272A CN202180013402.3A CN202180013402A CN115151272A CN 115151272 A CN115151272 A CN 115151272A CN 202180013402 A CN202180013402 A CN 202180013402A CN 115151272 A CN115151272 A CN 115151272A
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- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
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- C12N5/06—Animal cells or tissues; Human cells or tissues
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Abstract
优化嵌合抗原受体，特别是改造胞内信号域。
Description
PCT国内申请，说明书已公开。
Claims (11)
- PCT国内申请，权利要求书已公开。
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2020100917904 | 2020-02-13 | ||
| CN202010091790 | 2020-02-13 | ||
| PCT/CN2021/076247 WO2021160124A1 (zh) | 2020-02-13 | 2021-02-09 | 嵌合抗原受体的优化 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN115151272A true CN115151272A (zh) | 2022-10-04 |
Family
ID=77292973
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202180013402.3A Pending CN115151272A (zh) | 2020-02-13 | 2021-02-09 | 嵌合抗原受体的优化 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US20230340063A1 (zh) |
| EP (1) | EP4104850A4 (zh) |
| JP (1) | JP7439280B2 (zh) |
| CN (1) | CN115151272A (zh) |
| AU (1) | AU2021219886A1 (zh) |
| WO (1) | WO2021160124A1 (zh) |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20180186855A1 (en) * | 2016-03-23 | 2018-07-05 | Alector Llc | Chimeric receptors and methods of use thereof |
| WO2019006427A1 (en) * | 2017-06-29 | 2019-01-03 | Juno Therapeutics, Inc. | WALL MODEL FOR ASSESSING TOXICITIES ASSOCIATED WITH IMMUNOTHERAPIES |
| WO2019157461A1 (en) * | 2018-02-11 | 2019-08-15 | The Regents Of The University Of California | Car-t cells and autoimmune diseases |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20210322473A1 (en) * | 2018-07-18 | 2021-10-21 | The General Hospital Corporation | Modified t cells and methods of their use |
| WO2021190550A1 (zh) * | 2020-03-25 | 2021-09-30 | 上海先博生物科技有限公司 | 含有保护肽的嵌合抗原受体及其用途 |
-
2021
- 2021-02-09 CN CN202180013402.3A patent/CN115151272A/zh active Pending
- 2021-02-09 JP JP2022549228A patent/JP7439280B2/ja active Active
- 2021-02-09 US US17/799,492 patent/US20230340063A1/en active Pending
- 2021-02-09 EP EP21752943.7A patent/EP4104850A4/en active Pending
- 2021-02-09 WO PCT/CN2021/076247 patent/WO2021160124A1/zh unknown
- 2021-02-09 AU AU2021219886A patent/AU2021219886A1/en active Pending
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20180186855A1 (en) * | 2016-03-23 | 2018-07-05 | Alector Llc | Chimeric receptors and methods of use thereof |
| WO2019006427A1 (en) * | 2017-06-29 | 2019-01-03 | Juno Therapeutics, Inc. | WALL MODEL FOR ASSESSING TOXICITIES ASSOCIATED WITH IMMUNOTHERAPIES |
| WO2019157461A1 (en) * | 2018-02-11 | 2019-08-15 | The Regents Of The University Of California | Car-t cells and autoimmune diseases |
Non-Patent Citations (1)
| Title |
|---|
| JENNIFER A ROHRS: "Computational Model of Chimeric Antigen Receptors Explains Site-Specific Phosphorylation Kinetics", 《BIOPHYS》, vol. 115, no. 6, pages 1116 - 1129, XP055836099, DOI: 10.1016/j.bpj.2018.08.018 * |
Also Published As
| Publication number | Publication date |
|---|---|
| WO2021160124A1 (zh) | 2021-08-19 |
| US20230340063A1 (en) | 2023-10-26 |
| EP4104850A1 (en) | 2022-12-21 |
| EP4104850A4 (en) | 2023-09-20 |
| JP2023513821A (ja) | 2023-04-03 |
| JP7439280B2 (ja) | 2024-02-27 |
| AU2021219886A1 (en) | 2022-08-25 |
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