CN115089691A - 一种治疗感冒的壮药中药复方及制造方法 - Google Patents
一种治疗感冒的壮药中药复方及制造方法 Download PDFInfo
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Abstract
本发明公开了中医药技术领域的一种治疗感冒的壮药中药复方，包括桂枝、广藿香、苍术、石菖蒲、白芷、陈皮、茯苓、法半夏、南山楂、炙甘草、生姜，以桂枝、苍术解表散寒湿，可沟通阴阳表里，配合白芷、茯苓化中焦之湿浊，防止寒湿之邪侵犯中焦脾胃；藿香化湿，祛除失浊之弊，石菖蒲芳香辟浊，化痰湿，石菖蒲善行头面，头面为诸阳交会，可助桂枝开太阳经，从而使得寒邪有通路而散；陈皮化痰理气，取其宣发气机之功；法半夏辛开苦降，取其辛降化浊之功，通过调节气机升降、而化上中焦痰湿；用南山楂收敛五脏之气，使其宣中有收，预防气机耗散太过而伤及阳气。对于风寒感冒，风寒咳嗽，因风寒引起的扁桃体发炎等上呼吸道感染疾病有很好的治疗效果。
Description
技术领域
本发明属于中医药技术领域，具体是一种治疗感冒的壮药中药复方及制造方法。
背景技术
感冒是人们最常见的疾病之一，大多数感冒是由多种病毒引起的上呼吸道感染，感冒虽是一种自愈性疾病，但其发病率高，且其病发症状严重影响患者日常行为。
针对感冒，采用的治疗手段有很多种，西医治疗大多数以抗生素药物为主，治标不治本且副作用大，随着细菌耐药性和病毒的变异使得抗生素的功效日渐减弱；中医治疗则采用辨证施治，针对不同的症状采用不同的药物治疗。广西地处南方，南方气候以湿为主，人们受风着凉后，体内往往寒中带湿，因此，我们提出了一种适于南方的治疗风寒感冒的壮药中药复方及制造方法。
发明内容
为了解决上述问题，本发明的目的是提供一种治疗感冒的壮药中药复方及制造方法。
为了实现上述目的，本发明的技术方案如下：一种治疗感冒的壮药中药复方及制造方法，由以下重量份的组分组成：桂枝10-20g、广藿香10-20g、苍术10-20g、石菖蒲15-25g、白芷10-20g、陈皮10-20g、茯苓10-20g、法半夏15-25g、南山楂15-25g、炙甘草2-8g、生姜20-40g。
一种治疗感冒的壮药中药复方的制造方法，包括如下步骤：按重量份称取桂枝、广藿香、苍术、石菖蒲、白芷、陈皮、茯苓、法半夏、南山楂、炙甘草、生姜，将桂枝、苍术、茯苓、生姜加水浸泡，用于桂枝、苍术、茯苓、生姜浸泡的水是三种药物重量之和的5倍，用水蒸气蒸馏1-3小时后提取其挥发油，挥发油用β-环糊精包合，以减少储存过程中的氧化、变质及挥发性损失，包合物干燥后备用；将广藿香、石菖蒲、白芷、陈皮、法半夏、南山楂、炙甘草混合，加水煎煮2次，加水煎煮时先用武火煮沸后用文火继续煎煮，第一次在煎煮2小时提取一半，第二次在继续煎煮1小时后提取剩余煎液，合并煎液后过滤，滤液浓缩成清膏，所得清膏加入80％乙醇湿润制粒，干燥后与所得包合物混合得到颗粒状的成品。
采用上述方案后实现了以下有益效果：桂枝为主药，解表散寒湿，沟通阴阳表里；藿香芳香化湿，祛除失浊之弊；苍术配合白芷、茯苓可化中焦之湿浊，防止寒湿之邪侵犯中焦脾胃，进一步转换成太阴之病；苍术与石菖蒲配合芳香辟浊，化痰湿，石菖蒲善行头面，头面为诸阳交会，可助桂枝开太阳经，从而使得寒邪有通路而散；陈皮、法半夏为二陈汤之意，陈皮化痰理气，取其宣发气机之功；法半夏辛开苦降，取其辛降化浊之功；通过调节气机升降、而化上中焦痰湿。方中桂枝、苍术等药为辛散沟通阴阳表里之药物，故用南山楂收敛五脏之气，使其宣中有收，预防气机耗散太过而伤及阳气。对于风寒感冒，风寒咳嗽，因风寒引起的扁桃体发炎等上呼吸道感染疾病有很好的治疗效果，同时在2019-ncov感染的肺炎防治中也发挥了良好的效果，可做新冠肺炎预防中医汤药。
具体实施方式
下面通过具体实施方式进一步详细说明：
具体实施过程如下：
实施例一
一种治疗感冒的壮药中药复方，由以下重量份的组分组成：桂枝10-20g、广藿香10-20g、苍术10-20g、石菖蒲15-25g、白芷10-20g、陈皮10-20g、茯苓10-20g、法半夏15-25g、南山楂15-25g、炙甘草2-8g、生姜20-40g。
实施例二
一种治疗感冒的壮药中药复方，由以下重量份的组分组成：桂枝10g、广藿香10g、苍术10g、石菖蒲15g、白芷10g、陈皮10g、茯苓10g、法半夏15g、南山楂15g、炙甘草2g、生姜20g。
实施例三
一种治疗感冒的壮药中药复方，由以下重量份的组分组成：桂枝15g、广藿香15g、苍术15g、石菖蒲20g、白芷15g、陈皮15g、茯苓15g、法半夏20g、南山楂20g、炙甘草5g、生姜30g。
实施例四
一种治疗感冒的壮药中药复方，由以下重量份的组分组成：桂枝20g、广藿香20g、苍术20g、石菖蒲25g、白芷20g、陈皮20g、茯苓20g、法半夏25g、南山楂25g、炙甘草8g、生姜40g。
实施例五
一种治疗感冒的壮药中药复方的制造方法，包括如下步骤：按重量份称取桂枝、广藿香、苍术、石菖蒲、白芷、陈皮、茯苓、法半夏、南山楂、炙甘草、生姜，将桂枝、苍术、茯苓、生姜加水浸泡，用于桂枝、苍术、茯苓、生姜浸泡的水是三种药物重量之和的5倍，用水蒸气蒸馏1-3小时后提取其挥发油，挥发油用β-环糊精包合，以减少储存过程中的氧化、变质及挥发性损失，包合物干燥后备用；将广藿香、石菖蒲、白芷、陈皮、法半夏、南山楂、炙甘草混合，加水煎煮2次，加水煎煮时先用武火煮沸后用文火继续煎煮，第一次在煎煮2小时提取一半，第二次在继续煎煮1小时后提取剩余煎液，合并煎液后过滤，滤液浓缩成清膏，所得清膏加入80％乙醇湿润制粒，干燥后与所得包合物混合得到颗粒状的成品。实施例中原料的重量份数按照实施例1-4中任意一个进行选取。
在上述药物中，其中：
桂枝：具有发汗解肌，温通经脉，助阳化气，平冲降气的功效，常用于风寒感冒，脘腹冷痛，血寒经闭，关节痹痛，痰饮，水肿，心悸。
广藿香：有芳香化浊、发表解暑、开胃止呕的作用，可以治疗脘痞呕吐，暑湿倦怠，湿浊中阻，胸闷不舒，寒湿闭暑，鼻炎头痛等症状。
苍术：具有燥湿健脾、祛风除湿的功效，常用于治疗湿浊困脾和外感风湿等病症。
石菖蒲：具有化湿开胃，开窍豁痰，醒神益智。用于脘痞不饥，噤口下痢，神昏癫痫，健忘耳聋；理气，活血，散风，去湿；治癫痫，痰厥，热病神昏，健忘，气闭耳聋，心胸烦闷，胃痛，腹痛，风寒湿痹，痈疽肿毒，跌打损伤。
白芷：具有祛风止痛、解表散寒、消肿排脓、宣通鼻窍、祛风止痒、燥湿止带的效果。
陈皮：具有理气健脾、燥湿化痰的功效，主要用于脾胃气滞证，也可用于痰湿壅滞证。
茯苓：具有解毒祛湿，镇静安神、利尿消肿、健脾养胃的功效。
法半夏：具有燥湿化痰，降逆止呕，消痞散结，可改善心血管功能，用于湿痰咳嗽，风痰眩晕，痰厥头痛，呕吐反胃，胸脘痞闷，梅核气，瘿瘤痰核，痈疽肿毒。
南山楂：具有消积化滞，破气散瘀的功效，对心血管系统有降压、增加冠脉流量、降血脂等作用。
炙甘草：具有补脾和胃，益气复脉。用于脾胃虚弱，倦怠乏力，心动悸，脉结代，可解附子毒。
生姜：具有活血、祛寒、除湿、发汗、健胃止呕、驱腥臭、消水肿等功效。
上述药物根据壮药方搭配原则，由桂枝、苍术、广藿香、陈皮等11味药物制成。方中桂枝为主药，解表散寒湿，沟通阴阳表里；藿香芳香化湿，祛除失浊之弊；苍术配合白芷、茯苓可化中焦之湿浊，防止寒湿之邪侵犯中焦脾胃，进一步转换成太阴之病；苍术与石菖蒲配合芳香辟浊，化痰湿，石菖蒲善行头面，头面为诸阳交会，可助桂枝开太阳经，从而使得寒邪有通路而散；陈皮、法半夏为二陈汤之意，陈皮化痰理气，取其宣发气机之功；法半夏辛开苦降，取其辛降化浊之功；通过调节气机升降、而化上中焦痰湿。方中桂枝、苍术等药为辛散沟通阴阳表里之药物，故用南山楂收敛五脏之气，使其宣中有收，预防气机耗散太过而伤及阳气。对于风寒感冒，风寒咳嗽，因风寒引起的扁桃体发炎等上呼吸道感染疾病有很好的治疗效果，同时在2019-ncov感染的肺炎防治中也发挥了良好的效果，可做新冠肺炎预防中医汤药。
本发明产品为颗粒剂，密封包装后不仅方便患者携带，也更好的保存了药物，使其药效不会因外界环境影响而减弱。
经临床实验，取得了较好的有益技术效果，有关实验资料如下：
1.病例来源：门诊纳入风寒感冒病例100例，男性43例，女性57例，年龄6个月-57岁，包括轻度、中度、重度患者，发病至就诊时间为12小时-7天，症状包括不同程度的发热、干咳、有痰、咽干咽痛、便溏等。
2.治疗方法：颗粒剂兑水服用，一日三次，服用三天，服用期间忌辛辣生冷油腻食物。
3.观测指标：症状改善情况
4.统计学处理
表4-1治疗前后症状改善对比
5.结论
临床结果表明，经过一个疗程的治疗，轻度、中度患者均痊愈，重度患者症状明显缓解，继续服用一个疗程可痊愈，且治疗期间和痊愈后患者均无不良反应。
以上所述的仅是本发明的实施例，方案中公知的具体结构和/或特性等常识在此未作过多描述。应当指出，对于本领域的技术人员来说，在不脱离本发明结构的前提下，还可以作出若干变形和改进，这些也应该视为本发明的保护范围，这些都不会影响本发明实施的效果和专利的实用性。本申请要求的保护范围应当以其权利要求的内容为准，说明书中的具体实施方式等记载可以用于解释权利要求的内容。
Claims (8)
1.一种治疗感冒的壮药中药复方，其特征在于，由以下重量份的组分组成：桂枝10-20g、广藿香10-20g、苍术10-20g、石菖蒲15-25g、白芷10-20g、陈皮10-20g、茯苓10-20g、法半夏15-25g、南山楂15-25g、炙甘草2-8g、生姜20-40g。
2.根据权利要求1所述的治疗感冒的壮药中药复方，其特征在于，由以下重量份的组分组成：桂枝10g、广藿香10g、苍术10g、石菖蒲15g、白芷10g、陈皮10g、茯苓10g、法半夏15g、南山楂15g、炙甘草2g、生姜20g。
3.根据权利要求1所述的治疗感冒的壮药中药复方，其特征在于，由以下重量份的组分组成：桂枝15g、广藿香15g、苍术15g、石菖蒲20g、白芷15g、陈皮15g、茯苓15g、法半夏20g、南山楂20g、炙甘草5g、生姜30g。
4.根据权利要求1所述的治疗感冒的壮药中药复方，其特征在于，由以下重量份的组分组成：桂枝20g、广藿香20g、苍术20g、石菖蒲25g、白芷20g、陈皮20g、茯苓20g、法半夏25g、南山楂25g、炙甘草8g、生姜40g。
5.根据权利要求1-4任意一项所述的治疗感冒的壮药中药复方的制造方法，其特征在于，包括如下步骤：按重量份称取桂枝、广藿香、苍术、石菖蒲、白芷、陈皮、茯苓、法半夏、南山楂、炙甘草、生姜，将桂枝、苍术、茯苓、生姜加水浸泡，用水蒸气蒸馏后提取其挥发油，挥发油用β-环糊精包合，以减少储存过程中的氧化、变质及挥发性损失，包合物干燥后备用；将广藿香、石菖蒲、白芷、陈皮、法半夏、南山楂、炙甘草混合，加水煎煮2次，合并煎液后过滤，滤液浓缩成清膏，所得清膏加入80％乙醇湿润制粒，干燥后与所得包合物混合得到颗粒状的成品。
6.根据权利要求5所述的治疗感冒的壮药中药复方的制造方法，其特征在于，用于桂枝、苍术、茯苓浸泡的水是三种药物重量之和的5倍。
7.根据权利要求5所述的治疗感冒的壮药中药复方的制造方法，其特征在于，水蒸气蒸馏1-3小时。
8.根据权利要求5所述的治疗感冒的壮药中药复方的制造方法，其特征在于，加水煎煮时先用武火煮沸后用文火继续煎煮，第一次在煎煮2小时提取一半，第二次在继续煎煮1小时后提取剩余煎液。
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Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1057398A (zh) * | 1991-07-24 | 1992-01-01 | 四川涪陵制药厂 | 藿香正气液体口服制剂的制备方法 |
| CN102614451A (zh) * | 2012-04-20 | 2012-08-01 | 罗应平 | 一种温经散寒、温胃止呕、化湿开窍的中药 |
| CN106729580A (zh) * | 2017-02-14 | 2017-05-31 | 广西中医药大学第附属医院 | 治疗中风病急性期的中药 |
-
2022
- 2022-08-12 CN CN202210971252.3A patent/CN115089691A/zh active Pending
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1057398A (zh) * | 1991-07-24 | 1992-01-01 | 四川涪陵制药厂 | 藿香正气液体口服制剂的制备方法 |
| CN102614451A (zh) * | 2012-04-20 | 2012-08-01 | 罗应平 | 一种温经散寒、温胃止呕、化湿开窍的中药 |
| CN106729580A (zh) * | 2017-02-14 | 2017-05-31 | 广西中医药大学第附属医院 | 治疗中风病急性期的中药 |
Non-Patent Citations (1)
| Title |
|---|
| 庞婷婷等: "广西地区新型冠状病毒肺炎的中医壮医防治特点", 亚太传统医药 * |
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