CN115067351A - Pyrifluazuron suspending agent and preparation method and application thereof - Google Patents
Pyrifluazuron suspending agent and preparation method and application thereof Download PDFInfo
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- CN115067351A CN115067351A CN202210396088.8A CN202210396088A CN115067351A CN 115067351 A CN115067351 A CN 115067351A CN 202210396088 A CN202210396088 A CN 202210396088A CN 115067351 A CN115067351 A CN 115067351A
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- 239000000375 suspending agent Substances 0.000 title claims abstract description 25
- 238000002360 preparation method Methods 0.000 title claims abstract description 14
- LYCAIKOWRPUZTN-UHFFFAOYSA-N Ethylene glycol Chemical group OCCO LYCAIKOWRPUZTN-UHFFFAOYSA-N 0.000 claims abstract description 27
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 23
- 229920001285 xanthan gum Polymers 0.000 claims abstract description 19
- 239000000230 xanthan gum Substances 0.000 claims abstract description 19
- 229940082509 xanthan gum Drugs 0.000 claims abstract description 19
- 235000010493 xanthan gum Nutrition 0.000 claims abstract description 19
- 239000002270 dispersing agent Substances 0.000 claims abstract description 18
- 238000009736 wetting Methods 0.000 claims abstract description 18
- 239000006260 foam Substances 0.000 claims abstract description 15
- 239000003112 inhibitor Substances 0.000 claims abstract description 15
- 239000000725 suspension Substances 0.000 claims abstract description 11
- 229910019142 PO4 Inorganic materials 0.000 claims abstract description 9
- 239000004721 Polyphenylene oxide Substances 0.000 claims abstract description 9
- SNAAJJQQZSMGQD-UHFFFAOYSA-N aluminum magnesium Chemical compound [Mg].[Al] SNAAJJQQZSMGQD-UHFFFAOYSA-N 0.000 claims abstract description 9
- 239000010452 phosphate Substances 0.000 claims abstract description 9
- 229920000570 polyether Polymers 0.000 claims abstract description 9
- 239000000945 filler Substances 0.000 claims abstract description 8
- -1 phosphate ester Chemical class 0.000 claims abstract description 8
- 239000003755 preservative agent Substances 0.000 claims abstract description 8
- 230000002335 preservative effect Effects 0.000 claims abstract description 8
- 239000003795 chemical substances by application Substances 0.000 claims abstract description 7
- 239000000203 mixture Substances 0.000 claims description 69
- 239000004576 sand Substances 0.000 claims description 45
- 238000010008 shearing Methods 0.000 claims description 29
- 238000003756 stirring Methods 0.000 claims description 24
- 238000012546 transfer Methods 0.000 claims description 23
- 238000002156 mixing Methods 0.000 claims description 14
- 239000000498 cooling water Substances 0.000 claims description 12
- 238000003801 milling Methods 0.000 claims description 10
- 230000002013 molluscicidal effect Effects 0.000 claims description 8
- 239000002245 particle Substances 0.000 claims description 8
- 238000005086 pumping Methods 0.000 claims description 7
- 230000001276 controlling effect Effects 0.000 claims description 6
- 239000012452 mother liquor Substances 0.000 claims description 6
- 239000005893 Diflubenzuron Substances 0.000 claims description 5
- QQQYTWIFVNKMRW-UHFFFAOYSA-N diflubenzuron Chemical compound FC1=CC=CC(F)=C1C(=O)NC(=O)NC1=CC=C(Cl)C=C1 QQQYTWIFVNKMRW-UHFFFAOYSA-N 0.000 claims description 5
- 229940019503 diflubenzuron Drugs 0.000 claims description 5
- 239000003750 molluscacide Substances 0.000 claims description 4
- 239000010413 mother solution Substances 0.000 claims description 4
- 238000005070 sampling Methods 0.000 claims description 4
- NBIIXXVUZAFLBC-UHFFFAOYSA-K phosphate Chemical compound [O-]P([O-])([O-])=O NBIIXXVUZAFLBC-UHFFFAOYSA-K 0.000 claims description 3
- WFJFGMLKAISFOZ-UHFFFAOYSA-N 1-amino-3-iminourea Chemical group NN=C(O)N=N WFJFGMLKAISFOZ-UHFFFAOYSA-N 0.000 claims description 2
- 239000000463 material Substances 0.000 claims description 2
- 230000001105 regulatory effect Effects 0.000 claims description 2
- 230000002528 anti-freeze Effects 0.000 claims 1
- 239000004546 suspension concentrate Substances 0.000 claims 1
- 241000237858 Gastropoda Species 0.000 abstract description 15
- 241000534460 Ampullaria Species 0.000 abstract description 7
- 230000000361 pesticidal effect Effects 0.000 abstract description 3
- 239000000575 pesticide Substances 0.000 abstract description 3
- 230000000694 effects Effects 0.000 description 10
- 239000003814 drug Substances 0.000 description 8
- 238000012360 testing method Methods 0.000 description 7
- 229940079593 drug Drugs 0.000 description 5
- 238000011835 investigation Methods 0.000 description 5
- 239000000428 dust Substances 0.000 description 4
- 239000004563 wettable powder Substances 0.000 description 4
- 241000196324 Embryophyta Species 0.000 description 3
- 241000124008 Mammalia Species 0.000 description 3
- 241000209094 Oryza Species 0.000 description 3
- 235000007164 Oryza sativa Nutrition 0.000 description 3
- 238000001647 drug administration Methods 0.000 description 3
- 238000000034 method Methods 0.000 description 3
- 235000009566 rice Nutrition 0.000 description 3
- 239000004202 carbamide Substances 0.000 description 2
- 230000007547 defect Effects 0.000 description 2
- 238000007710 freezing Methods 0.000 description 2
- 239000013505 freshwater Substances 0.000 description 2
- 238000004519 manufacturing process Methods 0.000 description 2
- 238000012986 modification Methods 0.000 description 2
- 230000004048 modification Effects 0.000 description 2
- 238000012545 processing Methods 0.000 description 2
- 239000000126 substance Substances 0.000 description 2
- 231100000419 toxicity Toxicity 0.000 description 2
- 230000001988 toxicity Effects 0.000 description 2
- FMHDHIYHKKVRJU-UHFFFAOYSA-N (2-carbamoylphenyl) hypochlorite Chemical compound NC(=O)C1=CC=CC=C1OCl FMHDHIYHKKVRJU-UHFFFAOYSA-N 0.000 description 1
- JUIKUQOUMZUFQT-UHFFFAOYSA-N 2-bromoacetamide Chemical compound NC(=O)CBr JUIKUQOUMZUFQT-UHFFFAOYSA-N 0.000 description 1
- 241000282414 Homo sapiens Species 0.000 description 1
- 239000005956 Metaldehyde Substances 0.000 description 1
- 241001465754 Metazoa Species 0.000 description 1
- 241000565675 Oncomelania Species 0.000 description 1
- 208000030852 Parasitic disease Diseases 0.000 description 1
- 231100000674 Phytotoxicity Toxicity 0.000 description 1
- 241000570011 Pomacea canaliculata Species 0.000 description 1
- 206010070834 Sensitisation Diseases 0.000 description 1
- QAOWNCQODCNURD-UHFFFAOYSA-L Sulfate Chemical compound [O-]S([O-])(=O)=O QAOWNCQODCNURD-UHFFFAOYSA-L 0.000 description 1
- XSQUKJJJFZCRTK-UHFFFAOYSA-N Urea Chemical compound NC(N)=O XSQUKJJJFZCRTK-UHFFFAOYSA-N 0.000 description 1
- 238000003915 air pollution Methods 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 230000015556 catabolic process Effects 0.000 description 1
- 230000009194 climbing Effects 0.000 description 1
- 150000001875 compounds Chemical class 0.000 description 1
- 230000002950 deficient Effects 0.000 description 1
- 238000006731 degradation reaction Methods 0.000 description 1
- 238000011161 development Methods 0.000 description 1
- 239000002612 dispersion medium Substances 0.000 description 1
- 239000002552 dosage form Substances 0.000 description 1
- 231100000086 high toxicity Toxicity 0.000 description 1
- 230000002045 lasting effect Effects 0.000 description 1
- 231100000053 low toxicity Toxicity 0.000 description 1
- 239000002609 medium Substances 0.000 description 1
- GKKDCARASOJPNG-UHFFFAOYSA-N metaldehyde Chemical compound CC1OC(C)OC(C)OC(C)O1 GKKDCARASOJPNG-UHFFFAOYSA-N 0.000 description 1
- NYQXIOZBHWFCBU-UHFFFAOYSA-N n-phenylpyridine-3-carboxamide Chemical compound C=1C=CN=CC=1C(=O)NC1=CC=CC=C1 NYQXIOZBHWFCBU-UHFFFAOYSA-N 0.000 description 1
- RJMUSRYZPJIFPJ-UHFFFAOYSA-N niclosamide Chemical compound OC1=CC=C(Cl)C=C1C(=O)NC1=CC=C([N+]([O-])=O)C=C1Cl RJMUSRYZPJIFPJ-UHFFFAOYSA-N 0.000 description 1
- 229960001920 niclosamide Drugs 0.000 description 1
- 244000045947 parasite Species 0.000 description 1
- 230000002265 prevention Effects 0.000 description 1
- 230000008313 sensitization Effects 0.000 description 1
- HCJLVWUMMKIQIM-UHFFFAOYSA-M sodium;2,3,4,5,6-pentachlorophenolate Chemical compound [Na+].[O-]C1=C(Cl)C(Cl)=C(Cl)C(Cl)=C1Cl HCJLVWUMMKIQIM-UHFFFAOYSA-M 0.000 description 1
- 239000007921 spray Substances 0.000 description 1
- 238000003860 storage Methods 0.000 description 1
- 238000010998 test method Methods 0.000 description 1
- 239000002562 thickening agent Substances 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N47/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid
- A01N47/08—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid the carbon atom having one or more single bonds to nitrogen atoms
- A01N47/28—Ureas or thioureas containing the groups >N—CO—N< or >N—CS—N<
- A01N47/36—Ureas or thioureas containing the groups >N—CO—N< or >N—CS—N< containing the group >N—CO—N< directly attached to at least one heterocyclic ring; Thio analogues thereof
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N25/00—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests
- A01N25/02—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests containing liquids as carriers, diluents or solvents
- A01N25/04—Dispersions, emulsions, suspoemulsions, suspension concentrates or gels
Landscapes
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Health & Medical Sciences (AREA)
- Pest Control & Pesticides (AREA)
- Agronomy & Crop Science (AREA)
- Plant Pathology (AREA)
- Engineering & Computer Science (AREA)
- Dentistry (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Environmental Sciences (AREA)
- Dispersion Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Toxicology (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Abstract
The invention discloses a pyrifluazuron suspending agent and a preparation method and application thereof, and the pyrifluazuron suspending agent comprises the following components in percentage by mass: 20-40% of pyrifluazuron, 3% of wetting dispersant 1, 3% of wetting dispersant 2, 5% of antifreezing agent, 1% of tackifier 1, 0.15% of tackifier 2, 0.2% of preservative, 0.3% of foam inhibitor and the balance of filler, wherein the wetting dispersant 1 is EO-PO block polyether, the wetting dispersant 2 is phosphate ester, the antifreezing agent is ethylene glycol, the tackifier 1 is magnesium aluminum silicate, the tackifier 2 is xanthan gum, the preservative is KASON and the filler is water. The pyrifluazuron suspending agent prepared by the invention is applied to a paddy field system, can effectively prevent and control snail organisms such as paddy field ampullaria gigas and the like, is safe to non-target aquatic organisms and is environment-friendly; the pesticide has good dispersibility and spreadability, high suspension rate and strong capability of adhering to the surface of a plant body, so that the pesticide effect is durable.
Description
Technical Field
The invention belongs to the technical field of molluscacidal, and particularly relates to a pyrifluazuron suspending agent and a preparation method and application thereof.
Background
The freshwater snails such as oncomelania, ampullaria gigas and the like are intermediate hosts of a plurality of parasites, and the killing of the freshwater snails can effectively reduce and control the occurrence of parasitic diseases. Molluscicides fall into two broad categories: botanical drugs and pure chemically synthesized drugs. Among them, one kind of plant medicine has the advantages of good effect, easy degradation, low toxicity to environment and non-target organisms, but has the disadvantages of high production difficulty, high use cost and short lasting period; the other kind of pure chemical synthetic medicine, such as niclosamide, has good molluscicidal effect and small side effect on mammals such as human beings, but has high toxicity on non-target aquatic animals and is easy to cause serious loss on agricultural fishery production, and other chemical synthetic medicines, such as metaldehyde, sodium pentachlorophenate, bromoacetamide, nicotinanilide and chlorosalicylamide, cannot be popularized and used on a large scale due to the defects of medium toxicity on mammals, overhigh toxicity on mammals, sensitization in use, serious climbing in application, poor stability in storage process and the like.
The pyridylurea compound is a newly synthesized compound with molluscicidal activity, is also called as pyrifluazuron, is an N-pyridine-3-N '-4' -chlorphenyl urea compound, has the advantages of good molluscicidal effect and safety to non-target organisms, particularly aquatic organisms, but no mature product can be used at present, and great difficulty is caused to molluscicidal work. Therefore, the development of new dosage forms of piriurea appears to be very necessary.
Disclosure of Invention
The invention aims to overcome the defects of the prior art and provides a pyrifluazuron suspending agent and a preparation method and application thereof, and the technical scheme is as follows:
the pyrifluazuron suspending agent comprises the following components in percentage by mass: 20-40% of pyrifluazuron, 3% of wetting dispersant 1, 3% of wetting dispersant 2, 5% of antifreezing agent, 1% of tackifier 1, 0.15% of tackifier 2, 0.2% of preservative, 0.3% of foam inhibitor and the balance of filler, preferably 20% of pyrifluazuron.
The anti-freezing agent comprises a wetting dispersant 1, a tackifier 2, a wetting dispersant 2, a tackifier 1, a thickener 2, a preservative and a filler, wherein the wetting dispersant 1 is EO-PO block polyether, the wetting dispersant 2 is phosphate, the anti-freezing agent is ethylene glycol, the tackifier 1 is magnesium aluminum silicate, the tackifier 2 is xanthan gum, the preservative is kasong and the filler is water.
The existing piriurea products, such as the piriurea sulfate wettable powder, have good control effect and no obvious harm to fishes, but the wettable powder easily generates more dust during processing to cause air pollution, and the suspension rate is unstable when the wettable powder is used, so that the spray head of a sprayer is easily blocked. The pyrifluazuron suspending agent has no dust hazard during processing, has better dispersibility and spreadability, high suspension rate and stronger capability of adhering to the surface of a plant body, so the pyrifluazuron suspending agent has more remarkable and more durable pesticide effect than wettable powder.
The invention also provides a preparation method of the pyrifluazuron suspending agent, which comprises the following steps:
(1) adding 5% of ethylene glycol, 3% of phosphate ester, 3% of EO-PO block polyether, 0.2% of foam inhibitor and 35% of water into a shearing and stirring kettle in percentage by mass, after uniformly shearing and stirring, adding 20-40% of pyrifluazuron and 1% of magnesium aluminum silicate, and uniformly shearing and stirring;
(2) transferring the mixture which is sheared and uniformly stirred in the step (1) into a stirring kettle, and continuously stirring;
(3) transferring the mixture stirred in the step (2) into a primary sand mill, performing primary sand milling on the mixture, and transferring the mixture subjected to primary sand milling into a primary transfer tank;
(4) when the mixture in the first-stage transfer tank reaches 2%, performing secondary sanding on the mixture, and enabling the mixture after the secondary sanding to enter a second-stage transfer tank;
(5) when the mixture in the second-stage transfer tank reaches 1.5%, performing three-time sanding on the mixture, and enabling the mixture after the three-time sanding to enter a third-stage transfer tank; when the particle size D90 of the mixture after three times of sanding is less than or equal to 5 microns, transferring the mixture to a shearing and blending kettle, adding 7.5% of xanthan gum mother liquor, 0.2% of cason and 0.1% of foam inhibitor, shearing, adding proper amount of water, and uniformly mixing, wherein the content of xanthan gum in the xanthan gum mother liquor is 2%;
(6) and sampling from the shearing and blending kettle, inspecting and analyzing, and subpackaging after being qualified to obtain the pyrifluazuron suspending agent.
Preferably, the specific operation of step (1) is: starting a shearing stirring kettle to circulate cooling water, starting shearing, adding 35% of water in percentage by mass, then adding 5% of ethylene glycol, 3% of phosphate ester, 3% of EO-PO block polyether and 0.2% of foam inhibitor, starting a mixing stirrer, and stirring for 10min until the mixture is uniformly stirred; starting a single machine for dedusting, adding 20% of diflubenzuron and 1% of magnesium aluminum silicate, continuously shearing and stirring for 30min until the mixture is uniform, and closing the shearing.
Preferably, the specific operation of step (2) is: and (3) starting a circulating water pump of the stirring kettle, setting the frequency of the water pump to be 32Hz, starting an air compressor, and controlling the pressure to be 0.4Mpa by controlling the regulating valve.
Preferably, the specific operation of step (3) is: start one-level sand mill recirculated cooling water, start one-level sand mill charge pump, the pump material frequency of pump is 13 times/min, starts the main frame of one-level sand mill, and feed pressure is less than or equal to 0.5MPa, and the mixture begins the sanding, and the mixture after the sanding of once gets into one-level transit tank.
Preferably, the specific operation of step (4) is: when the mixture in the first-stage transfer tank reaches 2%, the circulating cooling water of the second-stage sand mill is started, the feeding pump of the second-stage sand mill is started, the pumping frequency of the pump is 15 times/min, the main machine of the second-stage sand mill is started, the feeding pressure is less than or equal to 0.5MPa, the mixture starts to be subjected to secondary sanding, and the mixture subjected to secondary sanding enters the second-stage transfer tank.
Preferably, the specific operation of step (5) is: when the mixture in the second-stage transfer tank reaches 1.5%, starting a third-stage sand mill to circulate cooling water, starting a feeding pump of the third-stage sand mill, wherein the pumping frequency of the pump is 15 times/min, starting a main machine of the third-stage sand mill, the feeding pressure is less than or equal to 0.5MPa, carrying out three-stage sand milling on the mixture, and feeding the mixture subjected to three-stage sand milling into the third-stage transfer tank; the particle size of the mixture is detected after the sand mill is used for sanding for 20min, when the particle size D90 of the mixture after the sand mill is used for sanding for three times is less than or equal to 5 microns, the mixture is transferred to a shearing and blending kettle, 7.5% xanthan gum mother solution, 0.2% cason and 0.1% foam inhibitor are added, the mixture is sheared for 10min, a proper amount of water is added, the mixture is uniformly mixed, and the content of xanthan gum in the xanthan gum mother solution is 2%.
The pyrifluazuron suspending agent prepared by the invention has good prevention and control effects when being applied as a molluscacide, and is difficult to cause the problems of flammability and phytotoxicity when water is used as a dispersion medium.
The invention has the beneficial effects that: the pyrifluazuron suspending agent prepared by the invention is applied to a paddy field system, can effectively prevent and control snail organisms such as paddy field ampullaria gigas and the like, is safe to non-target aquatic organisms and is environment-friendly; the pesticide has good dispersibility and spreadability, high suspension rate and strong capability of adhering to the surface of a plant body, so that the pesticide effect is durable. The preparation process of the pyrifluazuron suspending agent has no dust hazard, and is safe to operators and environment.
Detailed Description
The concept and technical effects of the present invention will be clearly and completely described in the following embodiments to fully understand the objects, aspects and effects of the present invention. It should be noted that the embodiments and features of the embodiments in the present application may be combined with each other without conflict.
Example 1
Preparing 200kg of pyrifluazuron suspension:
(1) 41.67kg of 96% pyrifluazuron original drug, 6kg of EO-PO block polyether wetting dispersant, 6kg of phosphate wetting dispersant, 10kg of ethylene glycol, 2kg of magnesium aluminum silicate, 0.3kg of xanthan gum, 0.4kg of carbazone, 0.6kg of foam inhibitor and 70kg of water are weighed.
(2) Starting a shearing stirring kettle to circulate cooling water, starting shearing, adding 70kg of water, then adding 10kg of ethylene glycol, 6kg of phosphate ester, 6kg of EO-PO block polyether and 0.4kg of foam inhibitor, starting a mixing stirrer, and stirring for 10min until the mixture is uniformly stirred; starting a single machine to remove dust, adding 41.67kg of 96% pyrifluazuron raw drug and 2kg of magnesium aluminum silicate, continuously shearing and stirring for 30min until the mixture is uniform, and closing the shearing.
(3) Transferring to a stirring kettle, continuing stirring, starting a circulating water pump of the stirring kettle, setting the frequency of the water pump to be 32Hz, starting an air compressor, controlling an adjusting valve, and controlling the pressure to be 0.4 Mpa.
(4) Transferring to a first-stage sand mill, starting circulating cooling water of the first-stage sand mill, starting a feeding pump of the first-stage sand mill, wherein the pumping frequency of the pump is 13 times/min, starting a main machine of the first-stage sand mill, the feeding pressure is less than or equal to 0.5MPa, the mixture starts to be sanded for one time, and the mixture after being sanded for one time enters a first-stage transfer tank.
(5) When the mixture in the first-stage transfer tank reaches 4kg, the circulating cooling water of the second-stage sand mill is started, the feeding pump of the second-stage sand mill is started, the pumping frequency of the pump is 15 times/min, the main machine of the second-stage sand mill is started, the feeding pressure is less than or equal to 0.5MPa, the mixture starts to be subjected to secondary sanding, and the mixture subjected to secondary sanding enters the second-stage transfer tank.
(6) When the mixture in the second-stage transfer tank reaches 3kg, starting a third-stage sand mill to circulate cooling water, starting a feeding pump of the third-stage sand mill, wherein the pumping frequency of the pump is 15 times/min, starting a main machine of the third-stage sand mill, the feeding pressure is less than or equal to 0.5MPa, carrying out three-stage sand milling on the mixture, and feeding the mixture subjected to three-stage sand milling into the third-stage transfer tank; and (3) detecting the particle size of the mixture after sanding for 20min by a sand mill, transferring the mixture to a shearing and blending kettle when the particle size D90 of the mixture after three times of sanding is less than or equal to 5 microns, adding 15kg of 7.5% xanthan gum mother liquor, 0.4kg of karson and 0.2kg of foam inhibitor, shearing for 10min, adding a proper amount of water to 200kg of the total mixture, and uniformly mixing until the content of xanthan gum in the xanthan gum mother liquor is 2%.
(7) Sampling from the shearing and blending kettle, inspecting and analyzing, and sending to a subpackaging workshop for subpackaging after being qualified to obtain the diflubenzuron suspending agent.
Example 2
Control effect test of 20% pyrifluazuron suspending agent:
(1) the test method comprises the following steps: the molluscicide is used for preventing and treating ampullaria gigas (GB/T17980.81-2004) in pesticide field efficacy test guidelines.
(2) Test subjects and crops: pomacea canaliculata and rice.
(3) Cell preparation: keeping the depth of a water layer of the rice field to be 4cm, keeping the water retention time to be equal to the last investigation time, surrounding a small area by a net with the height of 80cm, building a small ridge, independently draining and irrigating to prevent water cross, leaving a sidewalk, inserting 25 clusters of rice per square meter in the small area before snail placement, planting 4 snails in each cluster, and placing the snails after 1 week of planting. Each cell is lightly placed with ampullaria gigas of uniform size to form snails, and the density is controlled to be 10 per square meter.
(4) The test dosage and treatment number of the 20% pyrifluazuron suspension are shown in Table 1
TABLE 120% Coniro urea suspension test dosage and treatment number
(5) Cell area, repetition and spiral: 2m per cell 2 3 replicates and 20 ampullaria gigas of uniform size per cell.
(6) Investigation time, number of times and method: the test is carried out for 2 times of investigation, namely sampling investigation is carried out for 1 time respectively after 3 days and 7 days of the drug administration; the method comprises the following steps: during investigation, the number of the live snails and the dead snails which can be seen in the cell is checked, and after 7 days of medicine, all the bred snails are found out and the number of the live snails and the dead snails is checked (the number of the deficient snails is calculated according to the escape).
(7) The test results are shown in table 2:
table 2 mortality of ampullaria gigas into snails using different experimental dosages of 20% pyrifluazuron suspension
As can be seen from Table 2, when the 20% pyrifluazuron suspension is applied at a concentration of 0.2g/m 2 The curative effect is 66.67 percent and 71.67 percent respectively after 3 days and 7 days after the drug administration. When the concentration reaches 0.3g/m 2 In time, the curative effect is 98.33 percent and 95.00 percent respectively after 3 days and 7 days of the drug administration. It can be seen that 0.3g/m 2 The use concentration of the composition can achieve excellent control effect.
While the present invention has been described in considerable detail and with particular reference to several of these embodiments, it is not intended to be limited to any such details or embodiments or any particular embodiment, but rather it is to be construed as effectively covering the intended scope of the invention by providing a broad, potential interpretation of such claims in view of the prior art with reference to the appended claims. Furthermore, the foregoing describes the invention in terms of embodiments foreseen by the inventor for which an enabling description was available, notwithstanding that insubstantial modifications of the invention, not presently foreseen, may nonetheless represent equivalent modifications thereto.
Claims (10)
1. The pyrifluazuron suspending agent is characterized by comprising the following components in percentage by mass: 20-40% of pyrifluazuron, 3% of wetting dispersant 1, 3% of wetting dispersant 2, 5% of antifreezing agent, 1% of tackifier 1, 0.15% of tackifier 2, 0.2% of preservative, 0.3% of foam inhibitor and the balance of filler.
2. The pyrifluazuron suspension concentrate according to claim 1, characterized by comprising the following components in percentage by mass: 20% of pyrifluazuron, 3% of wetting dispersant 1, 3% of wetting dispersant 2, 5% of antifreezing agent, 1% of tackifier 1, 0.15% of tackifier 2, 0.2% of preservative, 0.3% of foam inhibitor and the balance of filling agent.
3. A pyriospironil suspending agent is characterized in that the wetting dispersant 1 is EO-PO block polyether, the wetting dispersant 2 is phosphate, the antifreeze is ethylene glycol, the tackifier 1 is magnesium aluminum silicate, the tackifier 2 is xanthan gum, the preservative is carbazone and the filler is water.
4. The preparation method of the pyrifluazuron suspending agent is characterized by comprising the following steps:
(1) adding 5% of ethylene glycol, 3% of phosphate ester, 3% of EO-PO block polyether, 0.2% of foam inhibitor and 35% of water into a shearing and stirring kettle in percentage by mass, after uniformly shearing and stirring, adding 20-40% of pyrifluazuron and 1% of magnesium aluminum silicate, and uniformly shearing and stirring;
(2) transferring the mixture which is sheared and uniformly stirred in the step (1) into a stirring kettle, and continuously stirring;
(3) transferring the mixture stirred in the step (2) into a primary sand mill, performing primary sand milling on the mixture, and transferring the mixture subjected to primary sand milling into a primary transfer tank;
(4) when the mixture in the first-stage transfer tank reaches 2%, performing secondary sanding on the mixture, and enabling the mixture after the secondary sanding to enter a second-stage transfer tank;
(5) when the mixture in the second-stage transfer tank reaches 1.5%, performing three-time sanding on the mixture, and enabling the mixture after the three-time sanding to enter a third-stage transfer tank; when the particle size D90 of the mixture after three times of sanding is less than or equal to 5 microns, transferring the mixture to a shearing and blending kettle, adding 7.5% of xanthan gum mother liquor, 0.2% of cason and 0.1% of foam inhibitor, shearing, adding proper amount of water, and uniformly mixing, wherein the content of xanthan gum in the xanthan gum mother liquor is 2%;
(6) and sampling from the shearing and blending kettle, inspecting and analyzing, and subpackaging after being qualified to obtain the diflubenzuron suspending agent.
5. The preparation method of the pyrifluazuron suspension agent according to claim 4, characterized in that the specific operation of the step (1) is as follows: starting a shearing stirring kettle to circulate cooling water, starting shearing, adding 35% of water in percentage by mass, then adding 5% of ethylene glycol, 3% of phosphate ester, 3% of EO-PO block polyether and 0.2% of foam inhibitor, starting a mixing stirrer, and stirring for 10min until the mixture is uniformly stirred; starting a single machine for dedusting, adding 20% of diflubenzuron and 1% of magnesium aluminum silicate, continuously shearing and stirring for 30min until the mixture is uniform, and closing the shearing.
6. The preparation method of the pyrifluazuron suspending agent according to claim 4, characterized in that the specific operation of the step (2) is as follows: and (3) starting a circulating water pump of the stirring kettle, setting the frequency of the water pump to be 32Hz, starting an air compressor, and controlling the pressure to be 0.4Mpa by controlling the regulating valve.
7. The preparation method of the pyrifluazuron suspension agent according to claim 4, characterized in that the specific operation of the step (3) is as follows: starting first-level sand mill recirculated cooling water, starting first-level sand mill charge pump, the pump material frequency of pump is 13 times/min, starts the main engine of first-level sand mill, and feed pressure is less than or equal to 0.5MPa, and the mixture begins the sanding, and the mixture after the sanding of once gets into one-level transit tank.
8. The preparation method of the pyrifluazuron suspension agent according to claim 4, characterized in that the specific operation of the step (4) is as follows: when the mixture in the first-stage transfer tank reaches 2%, the circulating cooling water of the second-stage sand mill is started, the feeding pump of the second-stage sand mill is started, the pumping frequency of the pump is 15 times/min, the main machine of the second-stage sand mill is started, the feeding pressure is less than or equal to 0.5MPa, the mixture starts to be subjected to secondary sanding, and the mixture subjected to secondary sanding enters the second-stage transfer tank.
9. The preparation method of the pyrifluazuron suspension as claimed in claim 4, characterized in that the specific operation of the step (5) is as follows: when the mixture in the second-stage transfer tank reaches 1.5%, starting a third-stage sand mill to circulate cooling water, starting a feeding pump of the third-stage sand mill, wherein the pumping frequency of the pump is 15 times/min, starting a main machine of the third-stage sand mill, the feeding pressure is less than or equal to 0.5MPa, carrying out three-stage sand milling on the mixture, and feeding the mixture subjected to three-stage sand milling into the third-stage transfer tank; the particle size of the mixture is detected after the sand mill is used for sanding for 20min, when the particle size D90 of the mixture after the sand mill is used for sanding for three times is less than or equal to 5 microns, the mixture is transferred to a shearing and blending kettle, 7.5% xanthan gum mother solution, 0.2% cason and 0.1% foam inhibitor are added, the mixture is sheared for 10min, a proper amount of water is added, the mixture is uniformly mixed, and the content of xanthan gum in the xanthan gum mother solution is 2%.
10. Use of a diflubenzuron suspension as defined in claims 1-3 as a molluscicide.
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| CN101491248A (en) * | 2008-01-22 | 2009-07-29 | 北京绿色农华植保科技有限责任公司 | Preparation method of fenpyroximate suspending agent |
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| WO2019072046A1 (en) * | 2017-10-11 | 2019-04-18 | 中国疾病预防控制中心寄生虫病预防控制所 | Use of pyridine urea compound having snail-killing activity |
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