CN107787994A - A kind of pyraclostrobin Difenoconazole micro-capsule suspension and preparation method thereof - Google Patents
A kind of pyraclostrobin Difenoconazole micro-capsule suspension and preparation method thereof Download PDFInfo
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- CN107787994A CN107787994A CN201610756383.4A CN201610756383A CN107787994A CN 107787994 A CN107787994 A CN 107787994A CN 201610756383 A CN201610756383 A CN 201610756383A CN 107787994 A CN107787994 A CN 107787994A
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- pyraclostrobin
- difenoconazole
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N47/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid
- A01N47/08—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid the carbon atom having one or more single bonds to nitrogen atoms
- A01N47/10—Carbamic acid derivatives, i.e. containing the group —O—CO—N<; Thio analogues thereof
- A01N47/24—Carbamic acid derivatives, i.e. containing the group —O—CO—N<; Thio analogues thereof containing the groups, or; Thio analogues thereof
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N25/00—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests
- A01N25/02—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests containing liquids as carriers, diluents or solvents
- A01N25/04—Dispersions, emulsions, suspoemulsions, suspension concentrates or gels
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N25/00—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests
- A01N25/26—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests in coated particulate form
- A01N25/28—Microcapsules or nanocapsules
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/64—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with three nitrogen atoms as the only ring hetero atoms
- A01N43/647—Triazoles; Hydrogenated triazoles
- A01N43/653—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
Abstract
The invention provides a kind of pyraclostrobin Difenoconazole micro-capsule suspension and preparation method thereof.The pyraclostrobin Difenoconazole micro-capsule suspension includes following each component by mass percentage：Pyraclostrobin：1%~20%；Difenoconazole：1%~40%；Cyst material：6%~10%；Capsule-core solvent：15%~20%；Emulsifying agent：1%~5%；Thickener：0.1%~1%；Dispersant：3%~5%；Antifreezing agent：1%~5%；Preservative：0.1%~0.5%；PH adjusting agent 1%~3%；Curing agent：0.1%~1%；Surplus is water.Pyraclostrobin Difenoconazole micro-capsule suspension of the present invention has the advantages that：The successful compounding of pyraclostrobin and Difenoconazole, there is synergy synergy, prevention effect significantly improves, and reduces Pesticide use amount, effectively reduces environmental pollution and residues of pesticides；Quick-acting is good and lasting effect is grown；It is green, there is good market potential.
Description
Technical field
The invention belongs to bactericide field, and in particular to a kind of pyraclostrobin-Difenoconazole micro-capsule suspension and
Its preparation method.
Background technology
It is well known that the growth of disease pest, disease to crops has very big harm, and chemical prevention is in plant disease pest, disease
Played a major role in evil.In recent years, the average annual Pesticide use amount in China is excessive, and wherein majority is chemical pesticide, therefore caused by
Environmental pollution and food-safety problem are increasingly serious, endanger the health of the mankind, it is seen that exploitation is less toxic, efficient, environment-friendly new
Type agricultural chemicals is the main outlet for realizing agricultural product security.
Difenoconazole (Difenoconazole) is a kind of systemic fungicide, tool protection and therapeutic action.It is triazole
Security is higher in series bactericidal agent, wide sterilization spectrum, to Ascomycetes, Basidiomycetes and including Alternaria, Ascochyta,
Partly know disease including Cercospora, Colletotrichum, ball Cuo Pseudomonas, Phoma, Ramularia, Septoria, Venturia, in vain
Powder Cordycepps, Uredinales and some Seedborne pathogens have lasting protection and therapeutic action；To bitter rot or anthracnose of grape, white rot effect
Very well.The yield and quality guarantee of crop can be improved by carrying out foliar treatment or seed treatment using it.Difenoconazole is extensive
Applied to crops such as fruit tree, vegetables, effectively prevent and treat scab, anthrachose of grape, white rot, spot defoliation, powdery mildew, brown spot,
Rust, stripe rust, head blight etc..
Pyraclostrobin (Pyraclostrobin) is new-type wide-spectrum bactericide.Pyraclostrobin suppresses for mitochondrial respiratory
Agent, i.e., by preventing electronics from shifting in being synthesized in cytochromes；It has protection, treatment, blade infiltration conduction.Pyrazoles ether
Bacterium emulsifiable concentrate shows to powdery mildew of cucumber, downy mildew and banana freckle, leaf spot, sclerotiniose etc. through field control effectiveness test result
There is preferable prevention effect.
However, in actual applications, Difenoconazole, the independent dispenser of pyraclostrobin or compounding use are present
Defect, for example, agricultural chemicals quick-acting is not good enough, overall usage amount is excessive, and the lasting period falls short of, and the technologies such as spraying times are excessive are asked
Topic.
Pesticide micro capsule suspending agent refers to form the small appearance of nucleocapsid structure using natural or synthesis high polymer material
Device, by agricultural chemicals cladding wherein, and it is suspended in the formulations of pesticide in water.It includes cyst wall and capsule-core two parts, and capsule-core is that agricultural chemicals has
It is the high polymer material of film forming to imitate composition and solvent, cyst wall.This formulation is divided into continuous phase and discontinuous phase, continuous phase be water and
Auxiliary agent, discontinuous phase are the agricultural chemicals tiny capsules being wrapped by.Microcapsule method is an important application in prepared by the formulations of pesticide
Technology, compared with conventional pesticide technology, microcapsules have protection core material material exempt from it is influenced by environmental conditions, make pesticide activity
The decomposition rate of composition slows down, reduces pesticide activity component volatilization loss, so as to obtain the utilization rate for improving active component, extends
Its lasting period, the advantages that reducing the number and frequency of dispenser.
The content of the invention
In order to overcome shortcomings and deficiencies present in above-mentioned prior art, inventor is by pyraclostrobin and Difenoconazole
Compounded, using pyraclostrobin-Difenoconazole after compounding as the active ingredient of the micro-capsule suspension, also, sent out
A person of good sense intends making full use of this one dosage type low temperature of micro-capsule suspension, prepares a kind of significant pyraclostrobin of synergistic effect-phenylate first
Ring azoles micro-capsule suspension, and obtain excellent prevention effect.
Pesticide micro capsule suspending agent mainly has following four advantages in itself：First, introduce sustained release and control release skill
Art, the agricultural chemicals lasting period is extended, reduce dispenser quantity and frequency, improved the utilization rate of agricultural chemicals, save pesticide dosage；The
Two, be prepared into the stability that agricultural chemicals can be improved after microcapsule formulations, avoid caused by environmental factor and other chemical substances effectively into
Point decomposition, oxidation, loss etc.；3rd, oil phase is separated from the water, to the agricultural chemicals of some water unstables, then can be processed into
Microcapsule formulations, expand the use range of agricultural chemicals, improve the compounding capacity with other agricultural chemicals；4th, microcapsule formulations can suppress agriculture
The volatility of medicine, shelters offending smell, reduces poisoning of the agricultural chemicals to the toxicity of people, animal and other animals and to crop, subtracts
Gently to the pressure of environment.
Therefore, the first aspect of the present invention provides a kind of pyraclostrobin-Difenoconazole micro-capsule suspension, described
Pyraclostrobin-Difenoconazole micro-capsule suspension includes following each component by mass percentage：Pyraclostrobin：1%
~20%；Difenoconazole：1%~40%；Cyst material：6%~10%；Capsule-core solvent：15%~20%；Emulsifying agent：1%
~5%；Thickener：0.1%~1%；Dispersant：3%~5%；Antifreezing agent：1%~5%；Preservative：0.1%~0.5%；
PH adjusting agent 1%~3%；Curing agent：0.1%~1%；Surplus is water.Wherein, the water is preferably deionization soft water.
Preferably, in above-mentioned pyraclostrobin-Difenoconazole micro-capsule suspension, the cyst material is selected from following
It is any one or more：Arabic gelatin, gum arabic, Lauxite, isocyanates, polyamine, melamine resin；The capsule-core
Solvent is turpentine-based vegetable oil.
Preferably, in above-mentioned pyraclostrobin-Difenoconazole micro-capsule suspension, the emulsifying agent is plant source waist
Fruit phenol polyethenoxy-oxypropylene block type polyethers.
Preferably, in above-mentioned pyraclostrobin-Difenoconazole micro-capsule suspension, the thickener is selected from following
It is a kind of：Xanthans, white carbon, Magnesiumaluminumsilicate.
Preferably, in above-mentioned pyraclostrobin-Difenoconazole micro-capsule suspension, the dispersant is selected from following
It is a kind of：Carboxylate, plant source cardanol polyoxyethylene ether phosphate, naphthalene sulfonate, alkylsulfonate, sodium alkyl benzene sulfonate, alkane
Base naphthalene sulfonate, alkylphenol-polyethenoxy base sodium sulphate.
Preferably, in above-mentioned pyraclostrobin-Difenoconazole micro-capsule suspension, the antifreezing agent be ethylene glycol or
Glycerine.
Preferably, in above-mentioned pyraclostrobin-Difenoconazole micro-capsule suspension, the preservative is sodium benzoate
Or OIT.
Preferably, in above-mentioned pyraclostrobin-Difenoconazole micro-capsule suspension, the pH adjusting agent is selected from following
It is any one or more：Hydrochloric acid, sodium hydroxide, glacial acetic acid, triethanolamine.
Preferably, in above-mentioned pyraclostrobin-Difenoconazole micro-capsule suspension, the curing agent is that formaldehyde is water-soluble
Liquid.
It can be seen that pyraclostrobin provided by the present invention-Difenoconazole micro-capsule suspension, be with pyraclostrobin and
Difenoconazole is active ingredient, is equipped with cyst material, capsule-core solvent, emulsifying agent, thickener, dispersant, antifreezing agent, anti-corrosion
Agent, curing agent, water and the micro-capsule suspension formed.Wherein, plant source cashew nut phenol polyethenoxy-polyoxy third as emulsifying agent
Alkene block type polyethers, it is not only cheap and easy to get as the turpentine-based vegetable oil of capsule-core solvent, and there is no toxic action to environment,
Obtained micro-capsule suspension is aided in improving the prevention effect of pyraclostrobin and Difenoconazole, and reduce agricultural chemicals
Production cost.
The second aspect of the present invention, there is provided pyraclostrobin-Difenoconazole is micro- described in a kind of first aspect present invention
The preparation method of capsule suspension, comprises the following steps：
(1) pyraclostrobin, capsule-core solvent are weighed by proportioning, added in container, temperature control heating, is sufficiently stirred, with complete
Dissolve pyraclostrobin；Emulsifying agent, cyst material and curing agent, stirring and dissolving are added, and uses pH adjusting agent regulation system
PH value to 5~6, pyraclostrobin microcapsules oil phase is made；
(2) Difenoconazole, dispersant, thickener, preservative, antifreezing agent and water are weighed by proportioning, adds another appearance
In device, after being sufficiently stirred, carry out homogeneous shearing and be sanded, difenoconazole suspending agent aqueous phase is made；
(3) in the presence of homogeneous shearing, by the pyraclostrobin microcapsules oil phase and the difenoconazole suspending
Agent aqueous phase mixes, and the pyraclostrobin-Difenoconazole micro-capsule suspension is made.
In summary, the preparation method of pyraclostrobin provided by the invention-Difenoconazole micro-capsule suspension, with multiple
Solidifying legal system obtains pyraclostrobin microcapsules oil phase, is sanded with wet method and difenoconazole suspending agent aqueous phase is made, then mixed in shearing
Final products are prepared in the presence of conjunction；The micro-capsule suspension has slowly release, improves the effect of lasting period, this is not only improved
The quick-acting of pyraclostrobin-Difenoconazole, meets the use demand of peasant, while also improves the lasting effect of preparation,
The Pesticide use frequency is reduced, reduces the usage amount of agricultural chemicals.In addition, the technique of the preparation method is simple, volume production can be effectively realized,
Thus there is very high application value.
In addition, pyraclostrobin of the present invention-Difenoconazole micro-capsule suspension is compared with prior art, at least
Following beneficial effect can also be produced：
(1) the successful compounding of pyraclostrobin and Difenoconazole, there is obvious synergy synergy, it is seen that preventing and treating effect
Fruit significantly improves, and reduces Pesticide use amount, effectively reduces environmental pollution and residues of pesticides, reduces the harm to beneficial organism；
(2) quick-acting is good and lasting effect is grown, and so as to save spraying times, reduces labour cost；(3) preparation method with it is obtained
The formulations of pesticide are green, have good market potential.
Brief description of the drawings
Fig. 1 is the technique stream of the preparation method of pyraclostrobin of the present invention-Difenoconazole micro-capsule suspension
Cheng Tu.
Embodiment
With reference to embodiment, the present invention is further elaborated, but the present invention is not limited to following embodiment party
Formula.
Embodiment 1
Pyraclostrobin-Difenoconazole micro-capsule suspension, wherein each group is prepared using technological process as shown in Figure 1
Point mass percent be：
Wherein, cyst material is Arabic gelatin, and capsule-core solvent is turpentine-based vegetable oil, and emulsifying agent is plant source anacardol
PULLRONIC F68 block type polyethers, thickener are xanthans, and dispersant is naphthalene sulfonate, and antifreezing agent is glycerine, are prevented
Rotten agent is OIT, and pH adjusting agent is glacial acetic acid and triethanolamine, and curing agent is formalin.
10g pyraclostrobins, 10g turpentine-based vegetable oils are weighed, is added in container, temperature control heating, is sufficiently stirred, with complete
Dissolve pyraclostrobin；Add 3g plant source anacardol PULLRONIC F68 block types polyethers, 6g Arab gelatin and
0.5g formalins, stirring and dissolving, and using the pH value of glacial acetic acid and triethanolamine regulation system to 5~6, pyrazoles ether is made
Bacterium ester microcapsules oil phase；Weigh 30g Difenoconazoles, 3g naphthalene sulfonates, 0.2g xanthans, 0.1g OITs, 4g the third three
Alcohol and 31.2g water, are added in another container, after being sufficiently stirred, are added in sand mill, are carried out homogeneous shearing and are sanded, are made
Difenoconazole suspending agent aqueous phase；In the presence of homogeneous shearing, by the pyraclostrobin microcapsules oil phase and the phenylate
Methyl cyclic-azole suspending agent aqueous phase mixes, and (40% active constituent content) pyraclostrobin-Difenoconazole micro-capsule suspension is made.
Embodiment 2
Pyraclostrobin-Difenoconazole micro-capsule suspension, wherein each group is prepared using technological process as shown in Figure 1
Point mass percent be：
Wherein, cyst material is isocyanates, and capsule-core solvent is turpentine-based vegetable oil, and emulsifying agent is that plant source anacardol gathers
Oxygen ethene-oxypropylene block type polyethers, thickener are xanthans, and dispersant is alkylnaphthalene sulfonate, and antifreezing agent is glycerine,
Preservative is sodium benzoate, and pH adjusting agent is glacial acetic acid, and curing agent is formalin.
15g pyraclostrobins, 15g turpentine-based vegetable oils are weighed, is added in container, temperature control heating, is sufficiently stirred, with complete
Dissolve pyraclostrobin；Add 4g plant source anacardol PULLRONIC F68 block types polyethers, 8g isocyanates and
0.6g formalins, stirring and dissolving, and use the pH value of glacial acetic acid regulation system that pyraclostrobin microcapsules are made to 5~6
Oil phase；Weigh 25g Difenoconazoles, 2.5g alkylnaphthalene sulfonates, 0.1g xanthans, 0.1g sodium benzoates, 4g glycerine and
26.7g water, add in another container, after being sufficiently stirred, be added in sand mill, carry out homogeneous shearing and be sanded, phenylate is made
Methyl cyclic-azole suspending agent aqueous phase；In the presence of homogeneous shearing, by the pyraclostrobin microcapsules oil phase and the phenyl ether methyl cyclic
Azole suspending agent aqueous phase mixes, and (40% active constituent content) pyraclostrobin-Difenoconazole micro-capsule suspension is made.
Embodiment 3
Pyraclostrobin-Difenoconazole micro-capsule suspension, wherein each group is prepared using technological process as shown in Figure 1
Point mass percent be：
Wherein, cyst material is melamine resin, and capsule-core solvent is turpentine-based vegetable oil, and emulsifying agent is that plant source anacardol gathers
Oxygen ethene-oxypropylene block type polyethers, thickener are xanthans, and dispersant is plant source cardanol polyoxyethylene ether phosphoric acid
Ester, antifreezing agent are glycerine, and preservative is sodium benzoate, and pH adjusting agent is glacial acetic acid, and curing agent is formalin.
5g pyraclostrobins, 10g turpentine-based vegetable oils are weighed, is added in container, temperature control heating, is sufficiently stirred, with complete
Dissolve pyraclostrobin；Add 3g plant source anacardol PULLRONIC F68 block types polyethers, 5g melamine resins and 1g
Formalin, stirring and dissolving, and use the pH value of glacial acetic acid regulation system that pyraclostrobin microcapsules oil is made to 5~6
Phase；Weigh 30g Difenoconazoles, 3g plant source cardanol polyoxyethylene ethers phosphate, 0.2g xanthans, 0.1g sodium benzoates,
5g glycerine and 36.7g water, are added in another container, after being sufficiently stirred, are added in sand mill, carry out homogeneous shearing sand
Mill, difenoconazole suspending agent aqueous phase is made；In the presence of homogeneous shearing, by the pyraclostrobin microcapsules oil phase and institute
The mixing of difenoconazole suspending agent aqueous phase is stated, (35% active constituent content) pyraclostrobin-Difenoconazole microcapsules are made
Suspending agent.
Embodiment 4
Pyraclostrobin-Difenoconazole micro-capsule suspension, wherein each group is prepared using technological process as shown in Figure 1
Point mass percent be：
Wherein, cyst material claps natural gum for me and I claps gelatin, and capsule-core solvent is turpentine-based vegetable oil, and emulsifying agent is
Plant source anacardol PULLRONIC F68 block type polyethers, thickener are xanthans, and dispersant is carboxylate, antifreezing agent
For ethylene glycol, preservative is sodium benzoate, and pH adjusting agent is glacial acetic acid and triethanolamine, and curing agent is formalin.
10g pyraclostrobins, 20g turpentine-based vegetable oils are weighed, is added in container, temperature control heating, is sufficiently stirred, with complete
Dissolve pyraclostrobin；Add 5g plant source anacardol PULLRONIC F68 block types polyethers, 6g I clap natural gum+
I claps gelatin and 1g formalins, stirring and dissolving, and using the pH value of glacial acetic acid and triethanolamine regulation system to 5~6,
Pyraclostrobin microcapsules oil phase is made；Weigh 30g Difenoconazoles, 2.5g carboxylates, 0.2g xanthans, 0.1g benzoic acid
Sodium, 4g glycerine and 40.2g water, are added in another container, after being sufficiently stirred, are added in sand mill, carry out homogeneous shearing
It is sanded, difenoconazole suspending agent aqueous phase is made；Homogeneous shearing in the presence of, by the pyraclostrobin microcapsules oil phase with
The difenoconazole suspending agent aqueous phase mixing, is made the micro- glue of (20% active constituent content) pyraclostrobin-Difenoconazole
Capsule suspending agent.
It is significant anti-in order to prove to have containing pyraclostrobin of the present invention-Difenoconazole micro-capsule suspension
Effect, inventor have carried out following crop field effect experiment：
A. use pyraclostrobin-Difenoconazole micro-capsule suspension made from embodiment 1~4 in field to cucumber cream
Mildew carries out the test of pesticide effectiveness, wherein using 100g/L pyraclostrobin missible oils and 40% difenoconazole suspending agent as comparison medicament,
Experimental result is shown in Table 1：
The field efficacy of 1 pyraclostrobin of table-Difenoconazole micro-capsule suspension preventing and treating cucumber downy mildew
Data result in table 1 shows, pyraclostrobin-Difenoconazole micro-capsule suspension in 7-14 days to cucumber
The prevention effect of downy mildew is above 85%, hence it is evident that better than comparison medicament；In terms of holding effect sex expression, pyraclostrobin-phenylate
For methyl cyclic-azole micro-capsule suspension in the prevention effect of 28 days up to more than 85%, the prevention effect at 42 days is also higher than 80%,
Generally it is better than comparison medicament；Show that the sustained release performance of the formulation is excellent.
B. use pyraclostrobin-Difenoconazole micro-capsule suspension made from embodiment 1~4 in field to Banana Leaf
Pinta carries out the test of pesticide effectiveness, wherein using 100g/L pyraclostrobin missible oils and 40% difenoconazole suspending agent as comparison medicament,
Experimental result is shown in Table 2：
The field efficacy of 2 pyraclostrobins of table-Difenoconazole micro-capsule suspension preventing and treating sigatoka
Data result in table 2 shows, pyraclostrobin-Difenoconazole micro-capsule suspension in 7-14 days to banana
The prevention effect of leaf spot is above 90%, hence it is evident that better than comparison medicament；In terms of holding effect sex expression, pyraclostrobin-phenylate
For methyl cyclic-azole micro-capsule suspension in the prevention effect of 28 days up to more than 85%, the prevention effect at 42 days is also higher than 80%,
Generally it is better than comparison medicament；Show that the sustained release performance of the formulation is excellent.C. pyraclostrobin-benzene made from embodiment 1~4 is used
Ether methyl cyclic-azole micro-capsule suspension carries out the test of pesticide effectiveness in field to wheat powdery mildew, wherein with 100g/L pyraclostrobin missible oils
It is comparison medicament with 40% difenoconazole suspending agent, experimental result is shown in Table 3：
The field efficacy of 3 pyraclostrobins of table-Difenoconazole micro-capsule suspension preventing and treating wheat powdery mildew
Data result in table 3 shows, pyraclostrobin-Difenoconazole micro-capsule suspension in 7-14 days to wheat
The prevention effect of powdery mildew is above 90%, hence it is evident that better than comparison medicament；In terms of holding effect sex expression, pyraclostrobin-phenylate
For methyl cyclic-azole micro-capsule suspension in the prevention effect of 28 days up to more than 90%, the prevention effect at 42 days is also higher than 85%,
Generally it is better than comparison medicament；Show that the sustained release performance of the formulation is excellent.
The specific embodiment of the present invention is described in detail above, but it is intended only as example, it is of the invention and unlimited
It is formed on particular embodiments described above.To those skilled in the art, it is any to the equivalent modifications that carry out of the present invention and
Substitute also all among scope of the invention.Therefore, the impartial conversion made without departing from the spirit and scope of the invention and
Modification, all should be contained within the scope of the invention.
Claims (10)
- A kind of 1. pyraclostrobin-Difenoconazole micro-capsule suspension, it is characterised in that the pyraclostrobin-phenylate first Ring azoles micro-capsule suspension includes following each component by mass percentage：Pyraclostrobin：1%~20%；Difenoconazole： 1%~40%；Cyst material：6%~10%；Capsule-core solvent：15%~20%；Emulsifying agent：1%~5%；Thickener：0.1% ~1%；Dispersant：3%~5%；Antifreezing agent：1%~5%；Preservative：0.1%~0.5%；PH adjusting agent 1%~3%；Solidification Agent：0.1%~1%；Surplus is water.
- 2. pyraclostrobin according to claim 1-Difenoconazole micro-capsule suspension, it is characterised in that the capsule Wall material is selected from following any one or more：It is Arabic gelatin, gum arabic, Lauxite, isocyanates, polyamine, close Polyimide resin；The capsule-core solvent is turpentine-based vegetable oil.
- 3. pyraclostrobin according to claim 1-Difenoconazole micro-capsule suspension, it is characterised in that the breast Agent is plant source anacardol PULLRONIC F68 block type polyethers.
- 4. pyraclostrobin according to claim 1-Difenoconazole micro-capsule suspension, it is characterised in that the increasing Thick dose selected from following any：Xanthans, white carbon, Magnesiumaluminumsilicate.
- 5. pyraclostrobin according to claim 1-Difenoconazole micro-capsule suspension, it is characterised in that described point Powder is selected from following any：Carboxylate, plant source cardanol polyoxyethylene ether phosphate, naphthalene sulfonate, alkylsulfonate, alkane Base benzene sulfonic acid sodium salt, alkylnaphthalene sulfonate, alkylphenol-polyethenoxy base sodium sulphate.
- 6. pyraclostrobin according to claim 1-Difenoconazole micro-capsule suspension, it is characterised in that described anti- It is ethylene glycol or glycerine to freeze agent.
- 7. pyraclostrobin according to claim 1-Difenoconazole micro-capsule suspension, it is characterised in that described anti- Rotten agent is sodium benzoate or OIT.
- 8. pyraclostrobin according to claim 1-Difenoconazole micro-capsule suspension, it is characterised in that the pH Conditioning agent is selected from following any one or more：Hydrochloric acid, sodium hydroxide, glacial acetic acid, triethanolamine.
- 9. pyraclostrobin according to claim 1-Difenoconazole micro-capsule suspension, it is characterised in that described solid Agent is formalin.
- A kind of 10. system of pyraclostrobin-Difenoconazole micro-capsule suspension according to any one of claim 1 ~ 9 Preparation Method, it is characterised in that comprise the following steps：（1）Pyraclostrobin, capsule-core solvent are weighed by proportioning, is added in container, temperature control heating, is sufficiently stirred, to be completely dissolved Pyraclostrobin；Emulsifying agent, cyst material and curing agent, stirring and dissolving are added, and uses the pH of pH adjusting agent regulation system Pyraclostrobin microcapsules oil phase is made to 5 ~ 6 in value；（2）Difenoconazole, dispersant, thickener, preservative, antifreezing agent and water are weighed by proportioning, is added in another container, After being sufficiently stirred, carry out homogeneous shearing and be sanded, difenoconazole suspending agent aqueous phase is made；（3）In the presence of homogeneous shearing, by the pyraclostrobin microcapsules oil phase and the difenoconazole suspending agent water Mix, the pyraclostrobin-Difenoconazole micro-capsule suspension is made.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
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| CN110089521A (en) * | 2019-04-03 | 2019-08-06 | 上海绿泽生物科技有限责任公司 | One kind is containing two class low melting point raw medicines compounding suspending agent and preparation method thereof |
| CN110973128A (en) * | 2019-12-25 | 2020-04-10 | 山东省绿士农药有限公司 | Benzopyrazole microcapsule suspending agent for preventing and treating gummy stem blight of watermelon and preparation method thereof |
| CN111226923A (en) * | 2020-03-09 | 2020-06-05 | 上海生农生化制品股份有限公司 | Pyraclostrobin-oxine-copper microcapsule suspension-suspending agent and preparation method thereof |
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| CN110973128A (en) * | 2019-12-25 | 2020-04-10 | 山东省绿士农药有限公司 | Benzopyrazole microcapsule suspending agent for preventing and treating gummy stem blight of watermelon and preparation method thereof |
| CN111226923A (en) * | 2020-03-09 | 2020-06-05 | 上海生农生化制品股份有限公司 | Pyraclostrobin-oxine-copper microcapsule suspension-suspending agent and preparation method thereof |
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