CN104719304A - Sedaxane-containing bactericidal composition - Google Patents
Sedaxane-containing bactericidal composition Download PDFInfo
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- CN104719304A CN104719304A CN201310714393.8A CN201310714393A CN104719304A CN 104719304 A CN104719304 A CN 104719304A CN 201310714393 A CN201310714393 A CN 201310714393A CN 104719304 A CN104719304 A CN 104719304A
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Abstract
The invention discloses a sedaxane-containing bactericidal composition. The sedaxane-containing bactericidal composition contains an active component A and an active component B, the active component A is sedaxane, and the active component B is one of tebuconazole, fludioxonil and difenoconazole, or the sedaxane-containing bactericidal composition contains an active component A, an active component B and an active component C, the active component A is sedaxane, the active component B is tebuconazole and the active component C is fludioxonil. The sedaxane-containing bactericidal composition produces synergism on a plurality of diseases harmful for agriculture production, reduces a pesticide use amount, reduces pesticide residual quantity of crops, reduces environment pollution, is safe for human and animals, has environment compatibility and does not cause resistance to pesticide.
Description
Technical field
The invention belongs to technical field of pesticide, relate to a kind of application of bactericidal composition on corps diseases of fluorine-containing azoles ring bacterium amine.
Background technology
Fluorine azoles ring bacterium amine (Sedaxane) is novel Fungicidal compounds, causing effect, mainly preventing and treating the disease such as head smut, smut of wheat, corn by suppressing germ succinate dehydrogenase.
Tebuconazole, fludioxonil or Difenoconazole all belong to common fungicide, are widely used in the disease of crops.
But in the real process of agricultural production, the problem that controlling disease the most easily produces is the generation of disease drug resistance.Different cultivars composition carries out composite, is to prevent and treat the very common method of resistance disease.Heterogeneity is carried out composite, according to practical application effect, judge certain composite be synergy, add and or antagonism.In most cases, the composite effect of sterilization is all additive effect, really has the seldom composite of synergistic effect, especially synergistic effect clearly, very high composite just less of synergy ratio.Study through inventor, find that fluorine azoles ring bacterium amine and Tebuconazole, fludioxonil, Difenoconazole is composite or fluorine azoles ring bacterium amine and Tebuconazole and fludioxonil can produce good synergistic effect after composite, and about fluorine azoles ring bacterium amine and Tebuconazole, fludioxonil, Difenoconazole composite or fluorine azoles ring bacterium amine and Tebuconazole and the composite relevant report of fludioxonil not yet open.
Summary of the invention
The object of the invention is to propose a kind of bactericidal composition with synergistic function, use cost is low, preventive effect is good fluorine-containing azoles ring bacterium amine.
The bactericidal composition of the fluorine-containing azoles ring bacterium amine that the present invention proposes, when effective active composition is two kinds of compounds, active components A is fluorine azoles ring bacterium amine, active component B is selected from any one compound following: Tebuconazole, fludioxonil, Difenoconazole, when effective active composition is three kinds of compounds, active components A is fluorine azoles ring bacterium amine, active component B is Tebuconazole, active component C is fludioxonil, the weight ratio of fluorine azoles ring bacterium amine and Tebuconazole is 80:1 ~ 1:80, the weight ratio of fluorine azoles ring bacterium amine and fludioxonil is 80:1 ~ 1:80, the weight ratio of fluorine azoles ring bacterium amine and Difenoconazole is 80:1 ~ 1:100, the weight ratio of fluorine azoles ring bacterium amine and Tebuconazole and fludioxonil is 1 ~ 80:1 ~ 80:1 ~ 80, the weight ratio being preferably fluorine azoles ring bacterium amine and Tebuconazole is 60:1 ~ 1:60, the weight ratio of fluorine azoles ring bacterium amine and fludioxonil is 60:1 ~ 1:60, the weight ratio of fluorine azoles ring bacterium amine and Difenoconazole is 60:1 ~ 1:80, and the weight ratio of fluorine azoles ring bacterium amine and Tebuconazole and fludioxonil is 1 ~ 60:1 ~ 60:1 ~ 60, the weight ratio being more preferably fluorine azoles ring bacterium amine and Tebuconazole is 30:1 ~ 1:30, the weight ratio of fluorine azoles ring bacterium amine and fludioxonil is 30:1 ~ 1:30, the weight ratio of fluorine azoles ring bacterium amine and Difenoconazole is 1:1 ~ 1:60, and the weight ratio of fluorine azoles ring bacterium amine and Tebuconazole and fludioxonil is 1 ~ 30:1 ~ 30:1 ~ 30.
The bactericidal composition of the fluorine-containing azoles ring bacterium amine that the present invention proposes is for preventing and treating the purposes of disease on crops, and described crops comprise cereal crops, legume crop, fiber crop, sugar [yielding, melon crop, fruits crop, dry fruit crop, hobby crop, root crop, oil crop, flower crop, medicinal crop, crop, green manure pasture crop; Described disease is black spot, downy mildew, gray mold, rust, leaf spot, powdery mildew, scab, spot defoliation, ring spot, white rot, anthrachose of grape, false smut, rice blast, bakanae disease, damping off, banded sclerotial blight, brown rot, smut, stalk break, root rot, fusarium wilt, leaf blight, early blight, spot blight, anthracnose or shot hole.
In usual composition, the weight percentage of active component is 0.5% ~ 90% of gross weight, is preferably 5% ~ 80%.According to different preparation types, active component content scope is different.Usually, liquid preparation contains the active substance of by weight 1% ~ 70%, is preferably 5% ~ 50%; Solid pharmaceutical preparation contains the active substance of by weight 5% ~ 80%, is preferably 10% ~ 80%.
At least containing a kind of surfactant in bactericidal composition of the present invention, the dispersion of active component in water when being beneficial to use.Surface-active contents is 5% ~ 30% of total formulation weight amount, and surplus is solid or liquid diluent.
Bactericidal composition of the present invention can by user before use through diluting or directly using.Its preparation can be prepared by common processing method known in those skilled in the art, after mixing with liquid flux or solid carrier by active substance, then add surfactant as one or more in dispersant, stabilizing agent, wetting agent, binding agent, defoamer, disintegrant, antifreeze etc.
Bactericidal composition of the present invention, acceptable formulation in any sterilization can be processed on demand, wherein preferred dosage form is wetting powder, water dispersible granules, suspending agent, suspension emulsion, aqueous emulsion, microemulsion, seed treatment microcapsule suspending agent, seed treatment microcapsule suspension-suspendinagent agent, seed treatment dry powder doses, seed treatment suspending agent, seed treatment emulsion, seed treatment dispersible pulvis, seed dressing, suspension seed-coating agent, most preferably is seed treatment microcapsule suspending agent, suspension seed-coating agent.
Composition comprises following constituent content when making wetting powder: active components A 0.1% ~ 80%, active component B0.1% ~ 80%, active component C0.1% ~ 80%, dispersant 2% ~ 10%, wetting agent 2% ~ 10%, filler surplus.
Composition comprises following constituent content when making water dispersible granules: active components A 0.1% ~ 80%, active component B0.1% ~ 80%, active component C0.1% ~ 80%, dispersant 3% ~ 12%, wetting agent 1% ~ 8%, disintegrant 1% ~ 10%, binding agent 0 ~ 8%, filler surplus.
Composition comprises following constituent content when making suspension seed-coating agent: active components A 0.1% ~ 50%, active component B0.1% ~ 50%, active component C0.1% ~ 50%, tackifier (0% ~ 2.0%), colouring agent (0.1% ~ 15%), antifreeze (0 ~ 8%), defoamer (0.01% ~ 2%), wetting agent (1.0% ~ 3.0%), dispersant (1.0% ~ 8.0%), film forming agent (0.5% ~ 5%).
Composition comprises following constituent content when making suspension emulsion: active components A 0.1% ~ 50%, active component B0.1% ~ 50%, active component C0.1% ~ 50%, dispersant 2% ~ 10%, defoamer 0.01% ~ 2%, solvent 1% ~ 15%, thickener 0 ~ 2%, emulsifier 2% ~ 12%, antifreeze 0 ~ 8%, deionized water add to 100%.
Composition comprises following constituent content when making aqueous emulsion: active components A 0.1% ~ 50%, active component B0.1% ~ 50%, active component C0.1% ~ 50%, solvent 1% ~ 30%, emulsifier 1% ~ 15%, antifreeze 0 ~ 8%, thickener 0 ~ 2%, defoamer 0.01% ~ 2%, deionized water supply surplus.
Composition comprises following constituent content when making microemulsion: active components A 0.1% ~ 50%, active component B0.1% ~ 50%, active component C0.1% ~ 50%, solvent 1% ~ 30%, emulsifier 3% ~ 25%, antifreeze 0 ~ 8%, defoamer 0.01% ~ 2%, deionized water supply surplus.
Composition comprises following constituent content when making seed treatment microcapsule suspending agent: active components A 0.1% ~ 50%, active component B0.1% ~ 50%, active component C0.1% ~ 50%, macromolecule cyst material 2% ~ 10%, dispersant 1% ~ 10%, organic solvent 1% ~ 10%, emulsifier 1% ~ 7%, defoamer 0.01% ~ 2%, pH adjusting agent 0.01% ~ 5%, deionized water add to 100%.
Composition comprises following constituent content when making seed treatment microcapsule suspension-suspendinagent agent: active components A 0.1% ~ 50%, active component B0.1% ~ 50%, active component C0.1% ~ 50%, macromolecule cyst material 2% ~ 10%, dispersant 1% ~ 12%, wetting agent 1% ~ 8%, organic solvent 1% ~ 15%, emulsifier 1% ~ 6%, defoamer 0.01% ~ 2%, thickener 0 ~ 2%, pH adjusting agent 0.01% ~ 5%, deionized water add to 100%;
Wetting powder the key technical indexes of the present invention:
Suspending agent the key technical indexes of the present invention:
Suspension emulsion the key technical indexes of the present invention:
Aqueous emulsion the key technical indexes of the present invention:
Microemulsion the key technical indexes of the present invention:
Microcapsule suspending agent the key technical indexes of the present invention:
Microcapsule suspension-suspendinagent agent the key technical indexes of the present invention:
Described dispersant is selected from alkylnaphthalene sulfonate, two (alkyl) naphthalenesulfonate formaldehyde condensation compound, naphthalene sulfonic acid-formaldehyde condensation product, aryl phenol polyoxyethylene succinate sulfonate, octylphenol polyethylene oxyethylene group ether sulfate, polycarboxylate, lignosulfonates, alkylaryl APEO, aliphatic alcohol polyethenoxy base ether, the phonetic formaldehyde condensation products sulphate of alkylphenol-polyethenoxy, alkyl benzene sulfonate calcium salt, naphthalene sulfonic acid-formaldehyde condensation product sodium salt, alkylphenol-polyethenoxy is phonetic, aliphatic amine polyoxyethylene is phonetic, polyoxyethylene carboxylate, one or more during ester polyoxyethylene is phonetic.
Described antifreeze is selected from: one or both in ethylene glycol, propane diols, glycerine, polyethylene glycol.
Described wetting agent is selected from: lauryl sodium sulfate, neopelex, Nekal BX, wetting and penetrating agent F, spaonin powder, sldium lauryl sulfate, tea are withered, one or more in silkworm excrement, soapberry powder.
Selected film forming agent ensures that limited farm chemical ingredients is concentrated and acts on seed and root, difficult drop-off and dispersing, and decreases agricultural chemicals diffusion in the environment and to the contact of non-target target, described suspension seed-coating agent also needs to comprise film forming agent.According to one or more in the preferential gum Arabic of film forming agent of the present invention, animal glue, pectin, xanthans, methylcellulose, ethyl cellulose, sodium carboxymethylcellulose, hydroxypropyl cellulose, sodium alginate, polyvinyl alcohol, polyethylene glycol, polyvinylpyrrolidone, polyacrylamide or Sodium Polyacrylate.
One or more in described tackifier xanthans, methylcellulose, gum Arabic, carboxymethyl cellulose, hydroxyethylcellulose, hydroxypropyl cellulose, PAA, sodium alginate, polyvinyl alcohol, polyacrylamide, Sodium Polyacrylate, aluminium-magnesium silicate.
Selected colouring agent: one or more in basic rhodamine, iron oxide red, water-based rhodo, acid scarlet, FGR-131, RED-131, RED8110.
Described defoamer is selected from: one or both in C8 ~ 10 aliphatic alcohols, C10 ~ 20 saturated fat acids, silicone defoaming agent.
The invention has the advantages that:
(1) the composite or fluorine azoles ring bacterium amine of fluorine azoles ring bacterium amine and Tebuconazole, fludioxonil, Difenoconazole and Tebuconazole and fludioxonil composite after, there is obvious synergy and lasting effect; (2) all greater activity is had to the disease on cereal crops, legume crop, fiber crop, sugar [yielding, melon crop, fruits crop, dry fruit crop, hobby crop, root crop, oil crop, flower crop, medicinal crop, crop, green manure pasture crop; (3) decrease pesticide usage amount, reduce the residual quantity of agricultural chemicals on crop, alleviate environmental pollution; (4) to person poultry safety, Environmental compatibility is good; And preparation adhesion strength strengthens, resistance of rainwater washing against.
Embodiment
Below in conjunction with embodiment to further instruction of the present invention, the percentage in embodiment is all weight percentage, but the present invention is not limited thereto.
Application Example one
Embodiment 1 ~ 40 suspension seed-coating agent
By wetting agent, dispersant, film forming agent, warning colouration, defoamer, antifreeze (can add and can not add), thickener (can add and can not add), mix through high speed shear, add fluorine azoles ring bacterium amine, active component B or active component B and active component C, ball milling 2 ~ 3 hours in ball mill, make diameter of particle all below 5 μm, surplus deionized water is supplied, and can obtain of the present invention kind of clothing suspending agent product, specifically in table 1 to table 8.
The each component of table 1 embodiment 1 ~ 5 and weight portion
The each component of table 2 embodiment 6 ~ 10 and weight portion
The each component of table 3 embodiment 11 ~ 15 and weight portion
The each component of table 4 embodiment 16 ~ 20 and weight portion
The each component of table 5 embodiment 21 ~ 25 and weight portion
The each component of table 6 embodiment 26 ~ 30 and weight portion
The each component of table 7 embodiment 31 ~ 35 and weight portion
The each component of table 8 embodiment 36 ~ 40 and weight portion
Embodiment 41 ~ 48 wetting powder
By fluorine azoles bacterium aniline, active ingredient B or fluorine azoles bacterium aniline, active ingredient B, active ingredient C, dispersant, wetting agent, filler mixing, mix in mixed cylinder, mix again after airslide disintegrating mill is pulverized, namely can be made into wetting powder product of the present invention.Specifically in table 9.
The each component of table 9 embodiment 41 ~ 48 and content
Embodiment 49 ~ 56 water dispersible granules
Fluorine azoles bacterium aniline, active component B or fluorine azoles bacterium aniline, active ingredient B, active ingredient C, dispersant, wetting agent, binding agent (can add and can not add), disintegrant, filler are obtained together the particle diameter of needs through air-flow crushing, obtain granulation materials.Item is quantitatively sent in fluidized bed granulating dryer through granulating and after drying, obtaining water dispersible granules product of the present invention.Specifically in table 10.
The each component of table 10 embodiment 49 ~ 56 and content
Embodiment 57 ~ 60 suspension emulsion
By dispersant, defoamer, thickener (can add and can not add), antifreeze (can add and can not add) in above-mentioned formulation material, mix through high speed shear, add fluorine azoles bacterium aniline, ball milling 2 ~ 3 hours in ball mill, make diameter of particle all below 5 μm, obtained fluorine azoles bacterium aniline suspending agent, then by active component B or active component B, active component C, solvent, emulsifier and the direct emulsification of various auxiliary agent high speed agitators in suspending agent, obtained suspension emulsion product of the present invention.Specifically in table 11.
The each component of table 11 embodiment 57 ~ 60 and content
Embodiment 61 ~ 64 aqueous emulsion
Fluorine azoles bacterium aniline, solvent, emulsifier are added together, make to be dissolved into homogeneous oil phase; Active component B, deionized water, antifreeze (can add and can not add), thickener (can add and can not add), defoamer to be mixed, become homogeneous aqueous phase.Under high velocity agitation, aqueous phase is added oil phase, obtained aqueous emulsion product of the present invention.Specifically in table 12.
The each component of table 12 embodiment 61 ~ 64 and content
Active component B Tebuconazole, fludioxonil, Difenoconazole or active component B in table 1 ~ 12 or active component C are exchanged, can novel formulation be obtained.
The embodiment of the present invention is the method adopting Toxicity Determination and field trial to combine.First by Toxicity Determination, the synergy ratio (SR) after clear and definite two kinds of medicaments are composite by a certain percentage, SR < 0.5 is antagonism, 0.5≤SR≤1.5 are summation action, SR > 1.5 is synergistic effect, on this basis, then carries out field trial.
Test method: determine that after the effective inhibition concentration scope of each medicament, medicament establishes 5 dosage process respectively by active constituent content through prerun, if clear water contrast.Carry out with reference to " farm-chemical indoor determination test rule bactericide ", adopt mycelial growth rate method to measure medicament to the virulence of crop germ.Measure colony diameter by right-angled intersection method after 72h, calculate each process net growth, mycelial growth inhibition rate.Net growth (mm)=measurement colony diameter-5
Mycelial growth inhibition rate is converted into probit value (y), and liquor strength (μ g/mL) converts logarithm value to (x), tries to achieve virulence regression equation (y=a+bx), and calculate the EC of often kind of medicament thus with method of least squares
50value.Calculate two medicament different ratio synergies ratio (SR) according to Wadley method, SR < 0.5 is antagonism, and 0.5≤SR≤1.5 are summation action simultaneously, and SR > 1.5 is synergistic effect.
(1), when effective active composition is two kinds of compounds, computing formula is as follows:
Wherein: a, b are respectively active components A and the ratio of active component B shared by combination;
A is fluorine azoles ring bacterium amine;
B is selected from the one in Tebuconazole, fludioxonil, Difenoconazole.
(2), when effective active composition is three kinds of compounds, computing formula is as follows:
Wherein: a, b, c are respectively fluorine azoles ring bacterium amine, Tebuconazole, ratio shared by fludioxonil;
Application Example two:
For examination disease: wheat smut; Test medicine provides by applicant.
Experimental scheme: through effective inhibition concentration scope of preliminary experiment determination fluorine azoles ring bacterium amine and Original Tebuconazole and the two different ratio mixture.
Toxicity test result
Table 13 fluorine azoles ring bacterium amine and the composite toxicity test analysis of results table to wheat smut of Tebuconazole
As shown in Table 13, fluorine azoles ring bacterium amine and Tebuconazole proportioning are all greater than 1.5 when 80:1 ~ 1:80 to the synergy ratio SR of wheat smut, both explanations mixture within the scope of 80:1 ~ 1:80 all shows synergistic effect, when the proportioning of fluorine azoles ring bacterium amine and Tebuconazole is at 30:1 ~ 1:30, synergistic effect is more outstanding, synergy ratio is all more than 2.20, discovery is tested through applicant, the optimum ratio of fluorine azoles ring bacterium amine and Tebuconazole is 30:1, 25:1, 20:1, 15:1, 14:1, 13:1, 12:1, 11:1, 10:1, 9:1, 8:1, 7:1, 6:1, 5:1, 4:1, 3:1, 2:1, 1:1, 1:2, 1:3, 1:4, 1:5, 1:6, 1:7, 1:8, 1:9, 1:10, 1:11, 1:12, 1:13, 1:14, 1:15, 1:16, 1:17, 1:18, 1:19, 1:20, 1:21, 1:22, 1:23, 1:24, 1:25, 1:26, 1:27, 1:28, 1:29, 1:30, wherein when fluorine azoles ring bacterium amine and tebuconazole weight are more maximum than synergy ratio when being 1:10, synergistic effect is the most obvious.
Application Example three:
For examination disease: the bunt of wheat; Test medicine provides by applicant.
Experimental scheme: through effective inhibition concentration scope of preliminary experiment determination fluorine azoles ring bacterium amine and the former medicine of fludioxonil and the two different ratio mixture.
Toxicity test result
Table 14 fluorine azoles ring bacterium amine and the composite toxicity test analysis of results table to the bunt of wheat of fludioxonil
As shown in Table 14, fluorine azoles ring bacterium amine and fludioxonil proportioning are all greater than 1.5 when 80:1 ~ 1:80 to the synergy ratio SR of the bunt of wheat, both explanations mixture within the scope of 80:1 ~ 1:80 all shows synergistic effect, when the proportioning of fluorine azoles ring bacterium amine and fludioxonil is at 30:1 ~ 1:30, synergistic effect is more outstanding, synergy ratio is all more than 2.20, discovery is tested through applicant, the optimum ratio of fluorine azoles ring bacterium amine and fludioxonil is 30:1, 25:1, 20:1, 19:1, 18:1, 17:1, 16:1, 15:1, 14:1, 13:1, 12:1, 11:1, 10:1, 9:1, 8:1, 7:1, 6:1, 5:1, 4:1, 3:1, 2:1, 1:1, 1:2, 1:3, 1:4, 1:5, 1:6, 1:7, 1:8, 1:9, 1:10, 1:11, 1:12, 1:13, 1:14, 1:15, 1:16, 1:17, 1:18, 1:19, 1:20, 1:25, 1:30, wherein when fluorine azoles ring bacterium amine and fludioxonil weight ratio are 2:1, synergy ratio is maximum, synergistic effect is the most obvious.
Application Example four:
For examination disease: loose smut of wheat; Test medicine provides by applicant.
Experimental scheme: through effective inhibition concentration scope of preliminary experiment determination fluorine azoles ring bacterium amine and difenoconazole technical material and the two different ratio mixture.
Toxicity test result
Table 15 fluorine azoles ring bacterium amine and the composite toxicity test analysis of results table to loose smut of wheat of Difenoconazole
As shown in Table 15, fluorine azoles ring bacterium amine and Difenoconazole proportioning are all greater than 1.5 when 80:1 ~ 1:80 to the synergy ratio SR of loose smut of wheat, both explanations mixture within the scope of 80:1 ~ 1:80 all shows synergistic effect, when the proportioning of fluorine azoles ring bacterium amine and Difenoconazole is at 1:1 ~ 1:60, synergistic effect is more outstanding, synergy ratio, all more than 2.25, tests discovery through applicant, and the optimum ratio of fluorine azoles ring bacterium amine and Difenoconazole is 1:1, 1:2, 1:3, 1:4, 1:5, 1:6, 1:7, 1:8, 1:9, 1:10, 1:11, 1:12, 1:13, 1:14, 1:15, 1:16, 1:17, 1:18, 1:19, 1:20, 1:25, 1:26, 1:27, 1:28, 1:29, 1:30, 1:31, 1:32, 1:33, 1:34, 1:35, 1:36, 1:37, 1:38, 1:39, 1:40, 1:41, 1:42, 1:43, 1:44, 1:45, 1:46, 1:47, 1:48, 1:49, 1:50, 1:51, 1:52, 1:53, 1:54, 1:55, 1:60, wherein when fluorine azoles ring bacterium amine and Difenoconazole weight ratio are 1:35, synergy ratio is maximum, and synergistic effect is the most obvious.
Application Example five:
For examination disease: maize head smut; Test medicine provides by applicant.
Experimental scheme: through effective inhibition concentration scope of preliminary experiment determination fluorine azoles ring bacterium amine, Tebuconazole and the former medicine of fludioxonil and the two different ratio mixture.
Toxicity test result
Table 16 fluorine azoles ring bacterium amine, Tebuconazole and the composite toxicity test analysis of results table to maize head smut of fludioxonil
As shown in Table 16, fluorine azoles ring bacterium amine, Tebuconazole and fludioxonil proportioning are all greater than 1.5 when 1 ~ 80:1 ~ 80:1 ~ 80 to the synergy ratio SR of maize head smut, both explanations mixture in 1 ~ 80:1 ~ 80:1 ~ 80 scope all shows synergistic effect, when fluorine azoles ring bacterium amine, the proportioning of Tebuconazole and fludioxonil is when 1 ~ 30:1 ~ 30:1 ~ 30, synergistic effect is more outstanding, synergy ratio is all more than 2.20, discovery is tested through applicant, fluorine azoles ring bacterium amine, the optimum ratio of Tebuconazole and fludioxonil is 7:70:3, 4:15:1, 7:70:3, 1:10:2, 4:20:1, 1:30:1, 10:59:1, 1:20:4, 1:1:78, 68:1:1, 1:78:1, wherein when fluorine azoles ring bacterium amine, when Tebuconazole and fludioxonil weight ratio are 7:70:3, synergy ratio is maximum, synergistic effect is the most obvious.
Find through test simultaneously: fluorine azoles ring bacterium amine and active component B composite after, or the composite rear control to the black spot in various crop, downy mildew, gray mold, rust, leaf spot, powdery mildew, scab, spot defoliation, ring spot, white rot, anthrachose of grape, false smut, rice blast, bakanae disease, damping off, banded sclerotial blight, brown rot, smut, stalk break, root rot, fusarium wilt, leaf blight, early blight, spot blight, anthracnose or shot hole of fluorine azoles bacterium amine, Tebuconazole and fludioxonil has obvious synergistic effect, and synergy ratio SR is all greater than 1.5.
Effect experiment part: test medicine is researched and developed by applicant, provided, contrast medicament 3% fluorine azoles ring bacterium amine suspension seed-coating agent (autogamy), 2% Tebuconazole suspension seed-coating agent (commercial), 25g/l fludioxonil suspension seed-coating agent (commercial), 3% difenoconazole suspending seed-dressing agent (commercial).
Application Example hexafluoro azoles ring bacterium amine and active component B or fluorine azoles ring bacterium amine, Tebuconazole and fludioxonil and the composite control wheat diseases test of pesticide effectiveness thereof.
This test arrangement is in Liquan County, Xianyang, Shanxi province city, and investigation wheat diseases index before medicine, usual formulation rate is the weight ratio of seed dressing and seed is 1:30 ~ 60.Experimental result is as follows:
Table 17 fluorine azoles ring bacterium amine and active component B or fluorine azoles ring bacterium amine, Tebuconazole and fludioxonil and the composite control wheat diseases test of pesticide effectiveness thereof
As can be seen from Table 17, fluorine azoles ring bacterium amine and active component B or fluorine azoles ring bacterium amine, Tebuconazole and fludioxonil and composite after effectively can prevent and treat wheat diseases, through applicant test find fluorine azoles ring bacterium amine and active component B or fluorine azoles ring bacterium amine, Tebuconazole and fludioxonil and composite after also can effectively prevent and treat wheat powdery mildew, rust, loose kernel smut, bunt, banded sclerotial blight or root rot, control efficiency is all higher than 97%, be better than the preventive effect of single dose, and the preventive effect phase is long.In test scope of medication, target crop is had no adverse effects.
Application Example seven fluorine azoles ring bacterium amine and active component B or fluorine azoles ring bacterium amine, Tebuconazole and fludioxonil and the composite control of maize disease test of pesticide effectiveness thereof.
This test arrangement is at Xianyang, Shanxi province suburban area, and investigation maize diseases index before medicine, usual formulation rate is the weight ratio of seed dressing and seed is 1:30 ~ 60.Experimental result is as follows:
Table 18 fluorine azoles ring bacterium amine and active component B or fluorine azoles ring bacterium amine, Tebuconazole and fludioxonil and the composite control of maize disease test of pesticide effectiveness thereof
As can be seen from Table 18, fluorine azoles ring bacterium amine and active component B or fluorine azoles ring bacterium amine, Tebuconazole and fludioxonil and composite after can effective control of maize disease, through applicant test find fluorine azoles ring bacterium amine and active component B or fluorine azoles ring bacterium amine, Tebuconazole and fludioxonil and composite after also can effectively control of maize smut, maize sheath blight, corn downy mildew, control efficiency is all higher than 97%, be better than the preventive effect of single dose, and the preventive effect phase is long.In test scope of medication, target crop is had no adverse effects.
Application Example octafluoro azoles ring bacterium amine and active component B or fluorine azoles ring bacterium amine, Tebuconazole and fludioxonil and compositely prevent and treat the rice disease test of pesticide effectiveness.
This test arrangement is at Shaanxi Province's Hanzhong City, and investigation rice disease index before medicine, usual formulation rate is the weight ratio of seed dressing and seed is 1:30 ~ 60.Experimental result is as follows:
Table 19 fluorine azoles ring bacterium amine and active component B or fluorine azoles ring bacterium amine, Tebuconazole and fludioxonil and compositely prevent and treat the rice disease test of pesticide effectiveness
As can be seen from Table 19, fluorine azoles ring bacterium amine and active component B or fluorine azoles ring bacterium amine, Tebuconazole and fludioxonil and composite after effectively can prevent and treat rice disease, through applicant test find fluorine azoles ring bacterium amine and active component B or fluorine azoles ring bacterium amine, Tebuconazole and fludioxonil and composite after also can preventing and controlling green smut of rice, bakanae disease, damping off, banded sclerotial blight, control efficiency is all higher than 97%, be better than the preventive effect of single dose, and the preventive effect phase is long.In test scope of medication, target crop is had no adverse effects.
Application Example nine fluorine azoles ring bacterium amine and active component B or fluorine azoles ring bacterium amine, Tebuconazole and fludioxonil and the composite control grape disease test of pesticide effectiveness thereof.
This test arrangement is at Xianyang, Shanxi province suburban area, and investigation grape disease index before medicine, usual formulation rate is the weight ratio of seed dressing and seed is 1:30 ~ 60.Experimental result is as follows:
Table 20 fluorine azoles ring bacterium amine and active component B or fluorine azoles ring bacterium amine, Tebuconazole and fludioxonil and the composite control grape disease test of pesticide effectiveness thereof
As can be seen from Table 20, fluorine azoles ring bacterium amine and active component B or fluorine azoles ring bacterium amine, Tebuconazole and fludioxonil and composite after effectively can prevent and treat grape disease, through applicant test find fluorine azoles ring bacterium amine and active component B or fluorine azoles ring bacterium amine, Tebuconazole and fludioxonil and composite after also can effectively prevent and treat downy mildew of garpe, gray mold, anthrachose of grape, control efficiency is all higher than 97%, be better than the preventive effect of single dose, and the preventive effect phase is long.In test scope of medication, target crop is had no adverse effects.
Application Example ten fluorine azoles ring bacterium amine and active component B or fluorine azoles ring bacterium amine, Tebuconazole and fludioxonil and the composite control rape disease test of pesticide effectiveness thereof.
This test arrangement is at Shaanxi Province's Hanzhong City, and investigation rape disease index before medicine, usual formulation rate is the weight ratio of seed dressing and seed is 1:30 ~ 60.Experimental result is as follows:
Table 21 fluorine azoles ring bacterium amine and active component B or fluorine azoles ring bacterium amine, Tebuconazole and fludioxonil and the composite control rape disease test of pesticide effectiveness thereof
As can be seen from Table 21, fluorine azoles ring bacterium amine and active component B or fluorine azoles ring bacterium amine, Tebuconazole and fludioxonil and composite after can effectively prevent and treat rape disease, control efficiency, all higher than 97%, is better than the preventive effect of single dose, and the preventive effect phase is long.In test scope of medication, target crop is had no adverse effects.
After draw through tests different local throughout the country, fluorine azoles ring bacterium amine and active component B or fluorine azoles ring bacterium amine, Tebuconazole and fludioxonil and composite rear to the black spot in various crop, downy mildew, gray mold, rust, leaf spot, powdery mildew, scab, spot defoliation, ring spot, white rot, anthrachose of grape, false smut, rice blast, bakanae disease, damping off, banded sclerotial blight, brown rot, smut, stalk break, root rot, fusarium wilt, leaf blight, early blight, spot blight, the preventive effect of the Common Diseases such as anthracnose or shot hole is all more than 97%, be better than single dose preventive effect, synergistic effect is obvious.
Claims (9)
1. the bactericidal composition of a fluorine-containing azoles ring bacterium amine, it is characterized in that: effective active composition is active components A and active component B, active components A is fluorine azoles ring bacterium amine, active component B is selected from any one compound following: Tebuconazole, fludioxonil, Difenoconazole, wherein the weight ratio of fluorine azoles ring bacterium amine and Tebuconazole is 80:1 ~ 1:80, the weight ratio of fluorine azoles ring bacterium amine and fludioxonil is 80:1 ~ 1:80, and the weight ratio of fluorine azoles ring bacterium amine and Difenoconazole is 80:1 ~ 1:100.
2. the bactericidal composition of a fluorine-containing azoles ring bacterium amine, it is characterized in that: effective active composition is active components A, active component B and active component C, active components A is fluorine azoles ring bacterium amine, active component B is Tebuconazole, active component C is fludioxonil, and the weight ratio of fluorine azoles ring bacterium amine and Tebuconazole and fludioxonil is 1 ~ 80:1 ~ 80:1 ~ 80.
3. the bactericidal composition of fluorine-containing azoles ring bacterium amine according to claim 1, is characterized in that:
The weight ratio of fluorine azoles ring bacterium amine and Tebuconazole is 60:1 ~ 1:60,
The weight ratio of fluorine azoles ring bacterium amine and fludioxonil is 60:1 ~ 1:60,
The weight ratio of fluorine azoles ring bacterium amine and Difenoconazole is 60:1 ~ 1:80.
4. the bactericidal composition of fluorine-containing azoles ring bacterium amine according to claim 2, is characterized in that: the weight ratio of fluorine azoles ring bacterium amine and Tebuconazole and fludioxonil is 1 ~ 60:1 ~ 60:1 ~ 60.
5. the bactericidal composition of fluorine-containing azoles ring bacterium amine according to claim 3, is characterized in that:
The weight ratio of fluorine azoles ring bacterium amine and Tebuconazole is 30:1 ~ 1:30,
The weight ratio of fluorine azoles ring bacterium amine and fludioxonil is 30:1 ~ 1:30,
The weight ratio of fluorine azoles ring bacterium amine and Difenoconazole is 1:1 ~ 1:60.
6. the bactericidal composition of fluorine-containing azoles ring bacterium amine according to claim 4, is characterized in that: the weight ratio of fluorine azoles ring bacterium amine and Tebuconazole and fludioxonil is 1 ~ 30:1 ~ 30:1 ~ 30.
7. the bactericidal composition of fluorine-containing azoles ring bacterium amine according to any one of claim 1 to 6, is characterized in that: combination dosage form is wetting powder, water dispersible granules, suspending agent, suspension emulsion, aqueous emulsion, microemulsion, seed treatment microcapsule suspending agent, seed treatment microcapsule suspension-suspendinagent agent, suspension seed-coating agent.
8. the bactericidal composition of fluorine-containing azoles ring bacterium amine according to claim 7 is for preventing and treating the purposes of disease on crops.
9. purposes according to claim 8, is characterized in that: described disease is black spot, downy mildew, gray mold, rust, leaf spot, powdery mildew, scab, spot defoliation, ring spot, white rot, anthrachose of grape, false smut, rice blast, bakanae disease, damping off, banded sclerotial blight, brown rot, smut, stalk break, root rot, fusarium wilt, leaf blight, early blight, spot blight, anthracnose or shot hole.
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN104663671A (en) * | 2015-02-13 | 2015-06-03 | 安徽省农业科学院植物保护与农产品质量安全研究所 | Bactericidal composition containing sedaxane and tebuconazole |
| CN105010348A (en) * | 2015-07-10 | 2015-11-04 | 广东中迅农科股份有限公司 | Agricultural chemical composition containing fluorine-azole cyelafuramid, fludioxonil and fluorine-pyrrole furanone |
| CN107197872A (en) * | 2017-08-02 | 2017-09-26 | 广东广康生化科技股份有限公司 | Composition pesticide and its application comprising folpet and fluorine azoles ring bacterium amine |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101410016A (en) * | 2006-02-09 | 2009-04-15 | 先正达参股股份有限公司 | Fungicidal compositions |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN101410016A (en) * | 2006-02-09 | 2009-04-15 | 先正达参股股份有限公司 | Fungicidal compositions |
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| 无: "Method for protecting useful plants or plant propagation material", 《RESEARCH DISCLOSURE》 * |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104663671A (en) * | 2015-02-13 | 2015-06-03 | 安徽省农业科学院植物保护与农产品质量安全研究所 | Bactericidal composition containing sedaxane and tebuconazole |
| CN105010348A (en) * | 2015-07-10 | 2015-11-04 | 广东中迅农科股份有限公司 | Agricultural chemical composition containing fluorine-azole cyelafuramid, fludioxonil and fluorine-pyrrole furanone |
| CN105010348B (en) * | 2015-07-10 | 2018-08-14 | 广东中迅农科股份有限公司 | Composition pesticide containing fluorine azoles ring bacterium amine and fludioxonil and fluorine pyrrole furanone |
| CN107197872A (en) * | 2017-08-02 | 2017-09-26 | 广东广康生化科技股份有限公司 | Composition pesticide and its application comprising folpet and fluorine azoles ring bacterium amine |
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