CN105340898A - Sterilization composition containing penthiopyrad and fludioxonil - Google Patents
Sterilization composition containing penthiopyrad and fludioxonil Download PDFInfo
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- CN105340898A CN105340898A CN201510812451.XA CN201510812451A CN105340898A CN 105340898 A CN105340898 A CN 105340898A CN 201510812451 A CN201510812451 A CN 201510812451A CN 105340898 A CN105340898 A CN 105340898A
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- Prior art keywords
- fludioxonil
- pyrrole metsulfovax
- sterilization composition
- penthiopyrad
- bactericidal composition
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Abstract
The invention discloses a sterilization composition containing penthiopyrad and fludioxonil. According to the sterilization composition, penthiopyrad and fludioxonil are taken as the active ingredients, and weight ratio of penthiopyrad to fludioxonil ranges from 1:10 to 10:1; the total weight of penthiopyrad and fludioxonil accounts for 1 to 90% of the weight of the sterilization composition; the sterilization composition can be prepared into one agent selected from a water emulsion, a microemulsion, a suspending agent, a wettable powder, and a water dispersible granule, is used for preventing and treating cucurbites and tomato gray mould disease. Application amount of the sterilization composition is reduced, spraying times are reduced, application cost is reduced, and the sterilization composition is safe for crops.
Description
Technical field
The present invention relates to a kind of bactericidal composition containing pyrrole metsulfovax and fludioxonil, is with pyrrole metsulfovax and fludioxonil for active ingredient, for preventing and treating melon and graw mold of tomato.
Background technology
The resistance problem of agricultural disease is a global problem, is the emphasis problem that agricultural science and technology worker pays close attention to always.Along with the continuity year in year out of disease chemical control, the increase of Pesticide use amount and not scientifical use agricultural chemicals, germ resistance is day by day serious, and the germ kind producing resistance is on the increase.Meanwhile, the use agricultural chemicals of high strength, causes Practice for Pesticide Residue in Agricultural Products to exceed standard, environmental pollution and the increase of peasant's drug cost etc., is unfavorable for agricultural sustainable development.Therefore, the bactericide agricultural chemicals of efficient, the low toxicity of research and development, environmental protection has positive effect to agricultural sustainable development.
Pyrrole metsulfovax; English name: penthiopyrad; it is acid amide fungicides; there is interior suction and osmosis, mainly through suppressing mitochondrial succinate acid esters dehydrase, hindering tricarbonic acid cycle; make amino acid, sugar lacks, energy reduces; the division of interference cell and growth, have protection and therapeutic action, efficient to the powdery mildew of the crop such as melon, tomato, grape, strawberry, gray mold.
Fludioxonil, English name: fludioxonil is the pyroles bactericide of protectiveness, mainly through the transfer suppressing glucose phosphorylated relevant, and the mycelial growth of Antifungi, finally cause germ dead; Fludioxonil uses as foliage fungicide, to melon, graw mold of tomato special efficacy, has very strong protective effect.
The mixture of different pesticide species is the common methods of control agricultural pest.Being screened by formulation of pesticide, filter out rational formula, can effectively improve actual control efficiency, reduce dosage, reduce costs, delay the drug-fast generation of damage by disease and insect, is the important means that agricultural synthesis is administered.The recipe determination of the present inventor to pyrrole metsulfovax and fludioxonil conducts in-depth research, and finds that pyrrole metsulfovax and fludioxonil carry out mixture and have obvious synergistic effect in certain mixed ratio scope to multiple fungi, after further study, completes the present invention.
The mixture combination of pyrrole metsulfovax and fludioxonil and application there is no report at present.
Summary of the invention
The object that the present invention solves be to provide a kind of efficient, low toxicity and the lasting period long, effectively can prevent and treat a kind of bactericidal composition containing pyrrole metsulfovax and fludioxonil of agricultural fungal evil.
The present inventor, by the test of a large amount of indoor bioassay and field medicine effect test, finds that pyrrole metsulfovax and fludioxonil are with after certain part by weight mixture, have significant synergistic effect to melon and graw mold of tomato.
On the basis of above-mentioned discovery, after further study, define technical scheme of the present invention, that is: a kind of bactericidal composition containing pyrrole metsulfovax and fludioxonil, active ingredient is pyrrole metsulfovax and fludioxonil, pyrrole metsulfovax and fludioxonil ratio of weight and number is in the composition 1:10 ~ 10:1, and pyrrole metsulfovax and fludioxonil weight summation in the composition percentage by weight are 1% ~ 90%, and all the other are the pesticidal preparations auxiliary element that agriculturally can accept and allow to use.
Bactericidal composition of the present invention according to well known to a person skilled in the art method, can be processed into the application forms of the applicable agricultural uses such as aqueous emulsion, microemulsion, suspending agent, wetting powder, water dispersible granules.
Bactericidal composition of the present invention is also containing the auxiliary element of preparation needed for pesticidal preparations, comprise one or more mixing in emulsifier, wetting agent, stabilizing agent, dispersant, thickener, defoamer, antifreezing agent, disintegrant, binding agent, filler, filler, medium etc., be known substance, various auxiliary agents conventional in pesticidal preparations, can change to some extent according to different situations, be not particularly limited
Bactericidal composition of the present invention, for preventing and treating melon and graw mold of tomato, during dispenser should disease occur before or initial stage of origination use.
Bactericidal composition provided by the invention, usually adopts spray method to use, also can adopt other operation techniques agriculturally applied as required.
A kind of bactericidal composition containing pyrrole metsulfovax and fludioxonil provided by the invention has following beneficial effect:
1, bactericidal composition provided by the invention, obvious synergy or summation action is shown in certain ratio range, the control efficiency of composition to germ is significantly improved than single dose, reduce the using dosage of agricultural chemicals, decrease times for spraying, reduce drug cost, decrease the adverse effect of agricultural chemicals to ecotope.
2, bactericidal composition provided by the invention, the combination of two kinds of active ingredients, expands fungicidal spectrum, and a drug can solve multiple diseases problem, compensate for defect when single dose uses and limitation.
3, bactericidal composition provided by the invention, two kinds of active ingredient mechanism of action are not quite identical, can overcome the shortcoming that long-term single use easily produces resistance, extend the service life of medicament, to the comprehensive regulation important in inhibiting of germ resistance.
4, bactericidal composition provided by the invention, drug effect plays rapidly, and the lasting period is long, and use cost is low, easy to use, time saving and energy saving, and it applies huge economic benefit and social benefit.
Embodiment
In order to make object of the present invention, technical scheme and advantage more short and sweet, the following specific embodiment of the present invention is described, but the present invention is only limitted to absolutely not these embodiments.The following stated is only the good embodiment of the present invention, only for describing the present invention, can not be interpreted as the restriction to scope of the present invention.It should be pointed out that all any amendments done within the spirit and principles in the present invention, equivalent replacement and improvement etc., all should be included within protection scope of the present invention.Therefore, the protection domain of patent of the present invention should be as the criterion with claims.
Content described in embodiment is all weight percentage.
Embodiment 1:12% pyrrole metsulfovax fludioxonil suspending agent.
Concrete operation step is: first mixed by other auxiliary agent, and in clipper, shear-mixed is even, then adds pyrrole metsulfovax and fludioxonil, in ball crusher, grinds 2-3h, make a diameter all at below 5mm, can obtain 12% pyrrole metsulfovax fludioxonil suspending agent.
Embodiment 2:22% pyrrole metsulfovax fludioxonil aqueous emulsion.
Concrete operation step is: first pyrrole metsulfovax and fludioxonil, trimethylbenzene, Sorbitan fatty acid ester are mixed, and dissolves and becomes uniform oil phase.Again part water and other auxiliary agents are mixed, dissolve and become uniform aqueous phase.Then oil phase is added aqueous phase while high-speed stirred in a kettle., slowly add water to and reach phase inversion point, carry out high speed shear afterwards, and add remaining water, shear about 30min, 22% pyrrole metsulfovax fludioxonil aqueous emulsion can be obtained.
Embodiment 3:16% pyrrole metsulfovax fludioxonil microemulsion.
Concrete operation step is: first pyrrole metsulfovax and fludioxonil fatty acid methyl ester are dissolved completely, and then add other auxiliary agent, mix, finally add water, after fully stirring, can obtain 16% pyrrole metsulfovax fludioxonil microemulsion.
Embodiment 4:30% pyrrole metsulfovax fludioxonil wetting powder.
Concrete operation step is: pyrrole metsulfovax and fludioxonil, other auxiliary agent are fully stirred in stirred tank, mixes, can obtain 30% pyrrole metsulfovax fludioxonil wetting powder after airslide disintegrating mill is pulverized.
Embodiment 5:60% pyrrole metsulfovax fludioxonil water dispersible granules.
Concrete operation step is: pyrrole metsulfovax and fludioxonil, other auxiliary agent will be had to mix, pulverize with micro jet, add after mediating after carrying out granulation, drying, screening in fluidized-bed granulation dryer, 60% pyrrole metsulfovax fludioxonil water dispersible granules can be obtained.
Embodiment 6:24% pyrrole metsulfovax fludioxonil suspending agent.
Concrete operation step is: first mixed by other auxiliary agent, and in clipper, shear-mixed is even, then adds pyrrole metsulfovax and fludioxonil, in ball crusher, grinds 2-3h, make a diameter all at below 5mm, can obtain 24% pyrrole metsulfovax fludioxonil suspending agent.
Embodiment 7:22% pyrrole metsulfovax fludioxonil wetting powder.
Concrete operation step is: pyrrole metsulfovax and fludioxonil, other auxiliary agent are fully stirred in stirred tank, mixes, can obtain 22% pyrrole metsulfovax fludioxonil wetting powder after airslide disintegrating mill is pulverized.
Embodiment 8: indoor bioassay is tested.
Survey standard method NY/T1156.2-2006 with reference to raw, adopt pastille medium therapy: the liquid 6mL getting each single dose and mixture series concentration, adds in the PDA medium of the 54mL being cooled to 45 DEG C, makes the pastille culture medium flat plate of required final concentration.Then produce 6mm diameter mycelia block from the cultivation object bacteria colony edge of 7 days, move on each serial pastille medium, mycelia faces down, and each process repeats for 4 times.Be disposed, the constant temperature biochemical cultivation case being placed in 25 ± 1 DEG C is cultivated.
Take out culture medium flat plate after 3 days, measure each process colony diameter by right-angled intersection method, calculate the mycelial growth inhibition rate of each process.Be independent variable x according to the logarithm value of drug concentration (mg/L), with the probit value of corrected mortality for dependent variable y, set up virulence regression equation formula respectively, adopt DPS software to calculate the EC of single dose and each proportioning mixture
50and mixture co-toxicity coefficient.Co-toxicity coefficient (CTC) >=120 shows as synergistic effect; Co-toxicity coefficient (CTC)≤80 shows as antagonism; 80 < co-toxicity coefficient (CTC) < 120 show as summation action.Actual measurement toxicity index (ATI)=(standard agent EC
50/ reagent agent EC
50) × 100.Theoretical toxicity index (the TTI)=percentage composition of A (in the toxicity index × mixture of the A)+percentage composition of B (in the toxicity index × mixture of B).Co-toxicity coefficient (CTC)=[the theoretical toxicity index (TTI) of mixture actual measurement toxicity index (ATI)/mixture] × 100
Table 1, pyrrole metsulfovax and fludioxonil are to the indoor joint toxicity measuring result of graw mold of tomato germ
As can be seen from Table 1, it is 133.31,139.34,146.05,133.22,132.82,140.04 and 144.51 that pyrrole metsulfovax and fludioxonil combine graw mold of tomato germ CTC value with 10:1,5:1,3:1,1:1,1:3,1:5 and 1:10 respectively, illustrates that pyrrole metsulfovax and fludioxonil combination have synergistic effect to graw mold of tomato germ.
Table 2, pyrrole metsulfovax and fludioxonil are to the indoor joint toxicity measuring result of gray mold of cucumber germ
As can be seen from Table 2, it is 122.74,131.79,141.18,135.27,139.29,138.43 and 138.32 that pyrrole metsulfovax and fludioxonil combine gray mold of cucumber germ CTC value with 10:1,5:1,3:1,1:1,1:3,1:5 and 1:10 respectively, illustrates that pyrrole metsulfovax and fludioxonil combination have synergistic effect to melon gray mold germ.
Embodiment 9: control graw mold of tomato field control effectiveness test.
Test site is positioned at Ma An town, Huizhou, adopts spray-on process.Adopt 10% pyrrole metsulfovax suspending agent, 50% fludioxonil wetting powder medicament in contrast, 9 chemicals treatment are established in test altogether, each process repeats for 4 times, the sick number of sheets of tomato is investigated before dispenser, within after dispenser 3 days, 7 days, respectively investigate a control efficiency, record the disease number of sheets, calculate control efficiency, result of the test is as shown in table 3.
Table 3, pyrrole metsulfovax and fludioxonil combination control graw mold of tomato result of the test
As can be seen from Table 3, the effect of bactericidal composition of the present invention control graw mold of tomato is better than the process of each contrast single dose, pyrrole metsulfovax is described and fludioxonil is composite can improve control efficiency, reduces the using dosage of agricultural chemicals, decrease the impact of agricultural chemicals on environment, reduce drug cost.
Embodiment 10: control balsam pear gray mold field control effectiveness test.
Test site is positioned at Nan Bin farm, Sanya, Hainan Province, adopts spray-on process.Adopt 10% pyrrole metsulfovax suspending agent, 50% fludioxonil wetting powder medicament in contrast, 9 chemicals treatment are established in test altogether, each process repeats for 4 times, the sick number of sheets of balsam pear is investigated before dispenser, within after dispenser 3 days, 7 days, respectively investigate a control efficiency, record the disease number of sheets, calculate control efficiency, result of the test is as shown in table 4.
Table 4, pyrrole metsulfovax and fludioxonil combination control balsam pear gray mold result of the test
As can be seen from Table 4, the effect of bactericidal composition of the present invention control balsam pear gray mold is better than the process of each contrast single dose, pyrrole metsulfovax is described and fludioxonil is composite can improve control efficiency, reduces the using dosage of agricultural chemicals, decrease the impact of agricultural chemicals on environment, reduce drug cost.
Claims (3)
1. one kind contains the bactericidal composition of pyrrole metsulfovax and fludioxonil, it is characterized in that: active ingredient is pyrrole metsulfovax and fludioxonil, pyrrole metsulfovax and fludioxonil ratio of weight and number is in the composition 1:10 ~ 10:1, and pyrrole metsulfovax and fludioxonil weight summation in the composition percentage by weight are 1% ~ 90%.
2. a kind of bactericidal composition containing pyrrole metsulfovax and fludioxonil according to claim 1, is characterized in that: described bactericidal composition processing can become aqueous emulsion, microemulsion, suspending agent, wetting powder, water dispersible granules.
3. a kind of bactericidal composition containing pyrrole metsulfovax and fludioxonil according to claim 1 is preventing and treating the application on melon and graw mold of tomato.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
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| CN201510812451.XA CN105340898A (en) | 2015-11-19 | 2015-11-19 | Sterilization composition containing penthiopyrad and fludioxonil |
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| CN201510812451.XA CN105340898A (en) | 2015-11-19 | 2015-11-19 | Sterilization composition containing penthiopyrad and fludioxonil |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107980786A (en) * | 2018-01-18 | 2018-05-04 | 兴农药业（中国）有限公司 | A kind of composition pesticide containing pyrrole metsulfovax and its application |
| CN113615713A (en) * | 2021-08-09 | 2021-11-09 | 广东中迅农科股份有限公司 | Bactericidal composition for preventing and treating gray mold and preparation method thereof |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH11302110A (en) * | 1998-04-24 | 1999-11-02 | Mitsui Chem Inc | Composition of plant disease injury controlling agent |
-
2015
- 2015-11-19 CN CN201510812451.XA patent/CN105340898A/en active Pending
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH11302110A (en) * | 1998-04-24 | 1999-11-02 | Mitsui Chem Inc | Composition of plant disease injury controlling agent |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107980786A (en) * | 2018-01-18 | 2018-05-04 | 兴农药业（中国）有限公司 | A kind of composition pesticide containing pyrrole metsulfovax and its application |
| CN113615713A (en) * | 2021-08-09 | 2021-11-09 | 广东中迅农科股份有限公司 | Bactericidal composition for preventing and treating gray mold and preparation method thereof |
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