CN115038456A - 第二代塞尼卡谷病毒溶瘤治疗：组合物及其方法 - Google Patents

第二代塞尼卡谷病毒溶瘤治疗：组合物及其方法 Download PDF

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CN115038456A
CN115038456A CN202080065213.6A CN202080065213A CN115038456A CN 115038456 A CN115038456 A CN 115038456A CN 202080065213 A CN202080065213 A CN 202080065213A CN 115038456 A CN115038456 A CN 115038456A
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cancer
ifn
svv
inhibitor
antxr1
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CN202080065213.6A
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Chinese (zh)
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文森特·R·拉卡涅洛
艾米·B·罗森菲尔德
保罗·L·哈伦贝克
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Seneca Therapy
Columbia University in the City of New York
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Seneca Therapy
Columbia University in the City of New York
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    • A—HUMAN NECESSITIES
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    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A—HUMAN NECESSITIES
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    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/4738—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A61K31/553—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having at least one nitrogen and one oxygen as ring hetero atoms, e.g. loxapine, staurosporine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66—Microorganisms or materials therefrom
    • A61K35/76—Viruses; Subviral particles; Bacteriophages
    • A61K35/768—Oncolytic viruses not provided for in groups A61K35/761 - A61K35/766
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2866—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for cytokines, lymphokines, interferons
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    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
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    • C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011—Details
    • C12N2770/32011—Picornaviridae
    • C12N2770/32032—Use of virus as therapeutic agent, other than vaccine, e.g. as cytolytic agent
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/52—Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis

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  • Pathology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
CN202080065213.6A 2019-07-19 2020-07-20 第二代塞尼卡谷病毒溶瘤治疗：组合物及其方法 Pending CN115038456A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201962876191P 2019-07-19 2019-07-19
US62/876,191 2019-07-19
PCT/US2020/042795 WO2021016194A1 (en) 2019-07-19 2020-07-20 Second generation seneca valley virus oncolytic therapy: compositions and methods thereof

Publications (1)

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CN115038456A true CN115038456A (zh) 2022-09-09

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US (1) US12502414B2 (https=)
EP (1) EP3999087A4 (https=)
JP (1) JP2022541234A (https=)
KR (1) KR20220035931A (https=)
CN (1) CN115038456A (https=)
AU (1) AU2020315800A1 (https=)
BR (1) BR112022000928A2 (https=)
CA (1) CA3147640A1 (https=)
IL (1) IL289912A (https=)
WO (1) WO2021016194A1 (https=)

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WO2017096201A1 (en) 2015-12-02 2017-06-08 Memorial Sloan-Kettering Cancer Center Seneca valley virus (svv) cellular receptor targeted oncotherapy
BR112022000928A2 (pt) 2019-07-19 2022-03-08 Seneca Therapeutics Inc Terapia oncolítica do vírus seneca valley de segunda geração: composições e métodos da mesma
CN116059260A (zh) * 2023-03-07 2023-05-05 华南农业大学 Sva病毒在制备肿瘤防治药物中的应用及抗肿瘤组合物

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CN108601802A (zh) * 2015-12-02 2018-09-28 纪念斯隆-凯特林癌症中心 塞尼卡谷病毒（svv）细胞受体靶向的肿瘤治疗
CN109022374A (zh) * 2018-08-16 2018-12-18 华中农业大学 一种塞内卡谷病毒重组质粒、重组病毒及构建方法

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BR112022000928A2 (pt) 2022-03-08
CA3147640A1 (en) 2021-01-28
US12502414B2 (en) 2025-12-23
KR20220035931A (ko) 2022-03-22
EP3999087A1 (en) 2022-05-25
EP3999087A4 (en) 2023-08-23
IL289912A (en) 2022-03-01
AU2020315800A1 (en) 2022-03-03
WO2021016194A1 (en) 2021-01-28
US20220249584A1 (en) 2022-08-11
JP2022541234A (ja) 2022-09-22

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