CN115006271A - Efficient anti-aging moisturizing soothing repairing anti-wrinkle face cream containing neohesperidin dihydrochalcone extract - Google Patents
Efficient anti-aging moisturizing soothing repairing anti-wrinkle face cream containing neohesperidin dihydrochalcone extract Download PDFInfo
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- CN115006271A CN115006271A CN202210697276.4A CN202210697276A CN115006271A CN 115006271 A CN115006271 A CN 115006271A CN 202210697276 A CN202210697276 A CN 202210697276A CN 115006271 A CN115006271 A CN 115006271A
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- neohesperidin dihydrochalcone
- extract
- deionized water
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- 239000001329 FEMA 3811 Substances 0.000 title claims abstract description 63
- ITVGXXMINPYUHD-CUVHLRMHSA-N neohesperidin dihydrochalcone Chemical compound C1=C(O)C(OC)=CC=C1CCC(=O)C(C(=C1)O)=C(O)C=C1O[C@H]1[C@H](O[C@H]2[C@@H]([C@H](O)[C@@H](O)[C@H](C)O2)O)[C@@H](O)[C@H](O)[C@@H](CO)O1 ITVGXXMINPYUHD-CUVHLRMHSA-N 0.000 title claims abstract description 63
- 229940089953 neohesperidin dihydrochalcone Drugs 0.000 title claims abstract description 63
- 235000010434 neohesperidine DC Nutrition 0.000 title claims abstract description 63
- 239000000284 extract Substances 0.000 title claims abstract description 44
- 239000006071 cream Substances 0.000 title claims abstract description 29
- 230000003020 moisturizing effect Effects 0.000 title claims abstract description 25
- 230000001153 anti-wrinkle effect Effects 0.000 title claims abstract description 19
- 230000003712 anti-aging effect Effects 0.000 title claims abstract description 18
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical compound O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 45
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 claims abstract description 42
- 239000008367 deionised water Substances 0.000 claims abstract description 36
- 229910021641 deionized water Inorganic materials 0.000 claims abstract description 36
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- IIZPXYDJLKNOIY-JXPKJXOSSA-N 1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphocholine Chemical class CCCCCCCCCCCCCCCC(=O)OC[C@H](COP([O-])(=O)OCC[N+](C)(C)C)OC(=O)CCC\C=C/C\C=C/C\C=C/C\C=C/CCCCC IIZPXYDJLKNOIY-JXPKJXOSSA-N 0.000 claims abstract description 14
- UIVPNOBLHXUKDX-UHFFFAOYSA-N 3,5,5-trimethylhexyl 3,5,5-trimethylhexanoate Chemical compound CC(C)(C)CC(C)CCOC(=O)CC(C)CC(C)(C)C UIVPNOBLHXUKDX-UHFFFAOYSA-N 0.000 claims abstract description 14
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- YWIVKILSMZOHHF-QJZPQSOGSA-N sodium;(2s,3s,4s,5r,6r)-6-[(2s,3r,4r,5s,6r)-3-acetamido-2-[(2s,3s,4r,5r,6r)-6-[(2r,3r,4r,5s,6r)-3-acetamido-2,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-2-carboxy-4,5-dihydroxyoxan-3-yl]oxy-5-hydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-3,4,5-trihydroxyoxane-2- Chemical compound [Na+].CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@H](O[C@H]2[C@@H]([C@@H](O[C@H]3[C@@H]([C@@H](O)[C@H](O)[C@H](O3)C(O)=O)O)[C@H](O)[C@@H](CO)O2)NC(C)=O)[C@@H](C(O)=O)O1 YWIVKILSMZOHHF-QJZPQSOGSA-N 0.000 claims abstract description 14
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- FBPFZTCFMRRESA-KVTDHHQDSA-N D-Mannitol Chemical compound OC[C@@H](O)[C@@H](O)[C@H](O)[C@H](O)CO FBPFZTCFMRRESA-KVTDHHQDSA-N 0.000 claims description 11
- 229930195725 Mannitol Natural products 0.000 claims description 11
- HDTRYLNUVZCQOY-WSWWMNSNSA-N Trehalose Natural products O[C@@H]1[C@@H](O)[C@@H](O)[C@@H](CO)O[C@@H]1O[C@@H]1[C@H](O)[C@@H](O)[C@@H](O)[C@@H](CO)O1 HDTRYLNUVZCQOY-WSWWMNSNSA-N 0.000 claims description 11
- HDTRYLNUVZCQOY-LIZSDCNHSA-N alpha,alpha-trehalose Chemical compound O[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@@H]1O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1 HDTRYLNUVZCQOY-LIZSDCNHSA-N 0.000 claims description 11
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- NLJMYIDDQXHKNR-UHFFFAOYSA-K sodium citrate Chemical compound O.O.[Na+].[Na+].[Na+].[O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O NLJMYIDDQXHKNR-UHFFFAOYSA-K 0.000 claims description 11
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/60—Sugars; Derivatives thereof
- A61K8/602—Glycosides, e.g. rutin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9789—Magnoliopsida [dicotyledons]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9794—Liliopsida [monocotyledons]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/08—Anti-ageing preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/59—Mixtures
- A61K2800/592—Mixtures of compounds complementing their respective functions
- A61K2800/5922—At least two compounds being classified in the same subclass of A61K8/18
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/74—Biological properties of particular ingredients
- A61K2800/78—Enzyme modulators, e.g. Enzyme agonists
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Birds (AREA)
- Epidemiology (AREA)
- Botany (AREA)
- Dermatology (AREA)
- Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Gerontology & Geriatric Medicine (AREA)
- Cosmetics (AREA)
Abstract
The invention relates to the technical field of anti-wrinkle face cream, in particular to high-efficiency anti-aging moisturizing soothing repairing anti-wrinkle face cream containing a neohesperidin dihydrochalcone extract component, which comprises deionized water, isononyl isononanoate, butanediol, glycerol, cetostearyl alcohol, triglyceride, a neohesperidin dihydrochalcone extract, polydimethylsiloxane, xanthan gum, sodium hyaluronate, a plant extract, hydrogenated lecithin and polyethylene glycol, wherein the weight ratio of each component is as follows: 12-15 parts of deionized water, 4-6 parts of isononyl isononanoate, 4-5 parts of butanediol, 12-13 parts of glycerol, 4-7 parts of cetearyl alcohol, 3.5-5 parts of triglyceride, 12-14 parts of neohesperidin dihydrochalcone extract, 4.5-5.5 parts of polydimethylsiloxane, 4-5 parts of xanthan gum, 0.3-0.4 part of sodium hyaluronate, 2-3 parts of plant extract, 3.5-4 parts of hydrogenated lecithin and 5-7 parts of polyethylene glycol.
Description
Technical Field
The invention relates to the technical field of anti-wrinkle face cream, in particular to efficient anti-aging moisturizing, soothing, repairing and anti-wrinkle face cream containing a neohesperidin dihydrochalcone extract component.
Background
The existing face cream on the market has poor functions of resisting aging, moisturizing, relieving and repairing and resisting wrinkles, and cannot meet the requirements of users.
In conclusion, the invention provides the efficient anti-aging moisturizing soothing and restoring anti-wrinkle face cream containing the neohesperidin dihydrochalcone extract component to solve the problem.
Disclosure of Invention
The invention aims to provide a high-efficiency anti-aging moisturizing soothing and wrinkle-removing facial cream containing a neohesperidin dihydrochalcone extract component, so as to solve the problems in the background technology.
In order to achieve the purpose, the invention provides the following technical scheme:
a high-efficiency anti-aging moisturizing soothing repairing anti-wrinkle cream containing a neohesperidin dihydrochalcone extract component comprises deionized water, isononyl isononanoate, butanediol, glycerol, cetearyl alcohol, triglyceride, a neohesperidin dihydrochalcone extract, polydimethylsiloxane, xanthan gum, sodium hyaluronate, a plant extract, hydrogenated lecithin and polyethylene glycol, and the weight ratio of each component is as follows: 12-15 parts of deionized water, 4-6 parts of isononyl isononanoate, 4-5 parts of butanediol, 12-13 parts of glycerol, 4-7 parts of cetearyl alcohol, 3.5-5 parts of triglyceride, 12-14 parts of neohesperidin dihydrochalcone extract, 4.5-5.5 parts of polydimethylsiloxane, 4-5 parts of xanthan gum, 0.3-0.4 part of sodium hyaluronate, 2-3 parts of plant extract, 3.5-4 parts of hydrogenated lecithin and 5-7 parts of polyethylene glycol.
A method for preparing efficient anti-aging moisturizing soothing repairing anti-wrinkle cream containing neohesperidin dihydrochalcone extract comprises the following steps:
s1, uniformly stirring butanediol and xanthan gum, mixing sodium hyaluronate and deionized water, adding a mixture of propanediol and xanthan gum, uniformly stirring at 45-48 ℃, adding a plant extract, and continuously uniformly stirring and mixing to obtain a water-phase base agent;
s2, mixing glycerol, cetostearyl alcohol, triglyceride, isononyl isononanoate, polydimethylsiloxane and hydrogenated lecithin, heating to 20-33 ℃, and uniformly stirring to obtain an oil phase base agent;
s3, mixing the water phase base agent and the oil phase base agent, stirring for 20-25 min, adding the neohesperidin dihydrochalcone extract at 55-58 ℃, continuously stirring until the mixture is uniform and has no obvious granular sensation, cooling to 32-35 ℃, preserving the temperature for 30-35 min, and naturally cooling to obtain the efficient anti-aging moisturizing soothing and repairing anti-wrinkle cream.
As a preferred scheme of the invention, the neohesperidin dihydrochalcone extract is prepared by mixing sodium citrate, mannitol, trehalose and deionized water, and the components are as follows by weight ratio: 0.2-0.4 part of sodium citrate, 4-6 parts of mannitol, 0.5-0.69 part of trehalose, 8-11 parts of neohesperidin dihydrochalcone solution and 70-85 parts of deionized water.
As a preferable embodiment of the present invention, the preparation method of the neohesperidin dihydrochalcone extract comprises the following steps:
s11, adding water to dissolve sodium citrate, mannitol and trehalose, adjusting the pH value to 6.9-7.1 to obtain an extraction solution, heating the extraction solution to 73-75 ℃, keeping the temperature for 35min, cooling the extraction solution, and slowly adding a neohesperidin dihydrochalcone solution into the extraction solution when the temperature of the extraction solution is reduced to be below 55 ℃ to obtain a neohesperidin dihydrochalcone-containing liquid;
s12, cooling the liquid containing the neohesperidin dihydrochalcone to-8 ℃ within 68-73 min to obtain a first product, cooling the first product to-55-58 ℃ again and preserving heat for 85-100 min to obtain a second product, heating the second product to-45-48 ℃ first and preserving heat for 65-70 min at the heat preservation pressure of 32-34 bar, then heating to 13-15 ℃ and preserving heat for 100-120 min at the heat preservation pressure of 32-34 bar to obtain a third product, heating the third product to 28-32 ℃ and preserving heat for 38-44 min at the heat preservation pressure of 32-34 bar, and finally heating to 42-46 ℃ and preserving heat for 85-100 min at the heat preservation pressure of 10-15 bar to obtain the neohesperidin dihydrochalcone extract.
In a preferred embodiment of the present invention, the slowly adding the neohesperidin dihydrochalcone solution to the extraction solution in S11 requires uniform stirring to avoid foaming.
As a preferable scheme of the invention, the plant extract is prepared by mixing ginseng, dendrobium huoshanense, polygonum multiflorum, gentian, ethanol and deionized water, and the weight ratio of each component is as follows: 0.08-0.23 part of ginseng, 0.12-0.25 part of dendrobium huoshanense, 2.5-3.5 parts of polygonum multiflorum, 2-3 parts of felwort, 10-15 parts of ethanol and 20-25 parts of deionized water.
As a preferable embodiment of the present invention, the method for preparing the plant extract comprises the steps of:
s21, putting the ginseng, the dendrobium huoshanense, the polygonum multiflorum and the gentian into deionized water, heating to 75-78 ℃, keeping the temperature for 5-8 min, taking out, washing with the deionized water, and cooling;
s22, feeding the cooled ginseng, dendrobium huoshanense, polygonum multiflorum and gentian into a grinder for grinding, feeding the ground ginseng, dendrobium huoshanense, polygonum multiflorum and gentian into ethanol, heating to 25-30 ℃, preserving heat for 1.5-2 h, filtering, collecting filtrate, and concentrating under reduced pressure to obtain the plant extract.
In a preferred embodiment of the present invention, the particle size of the pulverized ginseng, dendrobium huoshanense, polygonum multiflorum and gentian in S22 is 30 to 35 μm.
Compared with the prior art, the invention has the beneficial effects that:
1. according to the invention, butanediol and xanthan gum are uniformly stirred, sodium hyaluronate and deionized water are mixed and then added into a mixture of propylene glycol and xanthan gum, plant extracts are uniformly added after stirring, a water phase base agent is prepared after continuously stirring and uniformly mixing, glycerol, cetearyl alcohol, triglyceride, isononyl isononanoate, polydimethylsiloxane and hydrogenated lecithin are mixed and then heated and uniformly stirred to prepare an oil phase base agent, the water phase base agent and the oil phase base agent are mixed and then stirred, a neohesperidin dihydrochalcone extract is added and continuously stirred until no obvious granular sensation exists, and after cooling, the efficient anti-aging, moisturizing, soothing and repairing anti-wrinkle cream is obtained, the neohesperidin dihydrochalcone extract has the function of non-specific opsonin, can mobilize phagocytic cells to phagocytize harmful substances remained in skin, and creates a good skin repairing microenvironment, thereby accelerating the metabolism of skin cells, quickly discharging skin metabolic wastes, repairing vascular endothelial cells, restoring the elasticity of peripheral blood vessels, improving skin microcirculation, promoting the normal and orderly progress of skin microcirculation system, leading the skin to be always in a healthy and transparent state, stimulating the skin cells to secrete various nutrient substances to achieve the effect of nourishing the skin, also being capable of being used as a chemotactic factor to induce the skin cells to migrate to damaged parts so as to induce the skin tissues to grow orderly, achieving the perfect repairing effect without scars and pigmentation, also being capable of stimulating the cells to secrete antioxidases such as superoxide dismutase, catalase and the like, eliminating excessive free radicals in vivo and delaying aging, meanwhile, the plant extract prepared by ginseng, dendrobium huoshanense, tuber fleeceflower root and gentian can contain effective components such as panaxatriol, dendrobine, emodin, rhein and various vitamins, the cream has the effects of regulating skin moisture, increasing skin elasticity, preventing skin wrinkles, promoting the activity of superoxide dismutase, obviously expanding blood vessels, accelerating blood circulation and delaying the aging process of cells, so the cream has the effects of inhibiting and delaying the premature senility phenomenon affecting beauty, and the produced cream has good and efficient anti-aging, moisturizing, relieving and repairing anti-wrinkle effects under the combined action of the neohesperidin dihydrochalcone extract and the plant extract.
Detailed Description
The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the embodiments of the present invention, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, rather than all embodiments, and all other embodiments obtained by a person of ordinary skill in the art without any creative work based on the embodiments of the present invention belong to the protection scope of the present invention.
Unless defined otherwise, all technical and scientific terms used herein have the same meaning as commonly understood by one of ordinary skill in the art to which this invention belongs, and the terms used herein in the specification of the present invention are for the purpose of describing particular embodiments only and are not intended to limit the present invention, and the term "and/or" as used herein includes any and all combinations of one or more of the associated listed items.
The invention provides a technical scheme that:
a high-efficiency anti-aging moisturizing soothing repairing anti-wrinkle cream containing a neohesperidin dihydrochalcone extract component comprises deionized water, isononyl isononanoate, butanediol, glycerol, cetearyl alcohol, triglyceride, a neohesperidin dihydrochalcone extract, polydimethylsiloxane, xanthan gum, sodium hyaluronate, a plant extract, hydrogenated lecithin and polyethylene glycol, wherein the weight ratio of each component is as follows: 12-15 parts of deionized water, 4-6 parts of isononyl isononanoate, 4-5 parts of butanediol, 12-13 parts of glycerol, 4-7 parts of cetearyl alcohol, 3.5-5 parts of triglyceride, 12-14 parts of neohesperidin dihydrochalcone extract, 4.5-5.5 parts of polydimethylsiloxane, 4-5 parts of xanthan gum, 0.3-0.4 part of sodium hyaluronate, 2-3 parts of plant extract, 3.5-4 parts of hydrogenated lecithin and 5-7 parts of polyethylene glycol.
A method for preparing efficient anti-aging moisturizing soothing repairing anti-wrinkle cream containing neohesperidin dihydrochalcone extract comprises the following steps:
s1, uniformly stirring butanediol and xanthan gum, mixing sodium hyaluronate and deionized water, adding a mixture of propanediol and xanthan gum, uniformly stirring at 45-48 ℃, adding a plant extract, and continuously uniformly stirring and mixing to obtain a water-phase base agent;
s2, mixing glycerol, cetostearyl alcohol, triglyceride, isononyl isononanoate, polydimethylsiloxane and hydrogenated lecithin, heating to 20-33 ℃, and uniformly stirring to obtain an oil phase base agent;
s3, mixing the water phase base agent and the oil phase base agent, stirring for 20-25 min, adding the neohesperidin dihydrochalcone extract at 55-58 ℃, continuously stirring until the mixture is uniform and has no obvious granular sensation, cooling to 32-35 ℃, preserving the temperature for 30-35 min, and naturally cooling to obtain the efficient anti-aging moisturizing soothing and repairing anti-wrinkle cream.
Further, the neohesperidin dihydrochalcone extract is prepared by mixing sodium citrate, mannitol, trehalose and deionized water, and the weight ratio of each component is as follows: 0.2-0.4 part of sodium citrate, 4-6 parts of mannitol, 0.5-0.69 part of trehalose, 8-11 parts of neohesperidin dihydrochalcone solution and 70-85 parts of deionized water.
Further, the preparation method of the neohesperidin dihydrochalcone extract comprises the following steps:
s11, adding water to dissolve sodium citrate, mannitol and trehalose, adjusting the pH value to 6.9-7.1 to obtain an extraction solution, heating the extraction solution to 73-75 ℃, keeping the temperature for 35min, cooling the extraction solution, and slowly adding a neohesperidin dihydrochalcone solution into the extraction solution when the temperature of the extraction solution is reduced to be below 55 ℃ to obtain a neohesperidin dihydrochalcone-containing liquid;
s12, cooling the liquid containing the neohesperidin dihydrochalcone to-8 ℃ within 68-73 min to obtain a first product, cooling the first product to-55-58 ℃ again and preserving heat for 85-100 min to obtain a second product, heating the second product to-45-48 ℃ first and preserving heat for 65-70 min at the heat preservation pressure of 32-34 bar, then heating to 13-15 ℃ and preserving heat for 100-120 min at the heat preservation pressure of 32-34 bar to obtain a third product, heating the third product to 28-32 ℃ and preserving heat for 38-44 min at the heat preservation pressure of 32-34 bar, and finally heating to 42-46 ℃ and preserving heat for 85-100 min at the heat preservation pressure of 10-15 bar to obtain the neohesperidin dihydrochalcone extract.
Further, in S11, the neohesperidin dihydrochalcone solution is slowly added to the extraction solution with uniform stirring to avoid foaming.
Further, the plant extract is prepared by mixing ginseng, dendrobium huoshanense, polygonum multiflorum, gentian, ethanol and deionized water, and the components are as follows according to the weight ratio: 0.08-0.23 part of ginseng, 0.12-0.25 part of dendrobium huoshanense, 2.5-3.5 parts of polygonum multiflorum, 2-3 parts of felwort, 10-15 parts of ethanol and 20-25 parts of deionized water.
Further, the preparation method of the plant extract comprises the following steps:
s21, putting the ginseng, the dendrobium huoshanense, the polygonum multiflorum and the gentian into deionized water, heating to 75-78 ℃, keeping the temperature for 5-8 min, taking out, washing with the deionized water, and cooling;
s22, feeding the cooled ginseng, dendrobium huoshanense, polygonum multiflorum and gentian into a grinder for grinding, feeding the ground ginseng, dendrobium huoshanense, polygonum multiflorum and gentian into ethanol, heating to 25-30 ℃, preserving heat for 1.5-2 h, filtering, collecting filtrate, and concentrating under reduced pressure to obtain the plant extract.
Further, the particle size of the ginseng, the dendrobium huoshanense, the polygonum multiflorum and the gentian which are crushed in the step S22 is 30-35 mu m.
The specific implementation case is as follows:
weighing 0.2 part of sodium citrate, 4 parts of mannitol, 0.5 part of trehalose, 8 parts of neohesperidin dihydrochalcone solution and 70 parts of deionized water, adding water to dissolve the sodium citrate, the mannitol and the trehalose, adjusting the pH value to 6.9 to obtain an extraction solution, heating the extraction solution to 73 ℃, preserving heat for 35min, cooling the extraction solution, slowly adding the neohesperidin dihydrochalcone solution into the extraction solution after the temperature of the extraction solution is reduced to be below 55 ℃, uniformly stirring to avoid generating foam to obtain a liquid containing the neohesperidin dihydrochalcone, cooling the liquid containing the neohesperidin dihydrochalcone to-8 ℃ in 68min to obtain a first product, cooling the first product to-55 ℃ again, preserving heat for 85min to obtain a second product, heating the second product to-45 ℃ first, preserving heat for 70min, preserving heat at the pressure of 34bar, heating to 13 ℃ and preserving heat for 100min, keeping the temperature at 34bar to obtain a third product, heating the third product to 32 deg.C and keeping the temperature for 44min at 34bar, and heating to 46 deg.C and keeping the temperature for 100min at 15bar to obtain neohesperidin dihydrochalcone extract;
weighing 0.08 part of ginseng, 0.12 part of dendrobium huoshanense, 2.5 parts of polygonum multiflorum, 2 parts of gentian, 10 parts of ethanol and 20 parts of deionized water, feeding the ginseng, the dendrobium huoshanense, the polygonum multiflorum and the gentian into the deionized water, heating to 78 ℃, keeping the temperature for 8min, taking out, washing with the deionized water for cooling, feeding the cooled ginseng, the dendrobium huoshanense, the polygonum multiflorum and the gentian into a grinder for grinding, keeping the particle size of the ground ginseng, dendrobium huoshanense, the polygonum multiflorum and the gentian to 35 mu m, feeding the ground ginseng, dendrobium huoshanense, the polygonum multiflorum and the gentian into the ethanol, heating to 30 ℃, keeping the temperature for 2h, filtering, collecting filtrate, and concentrating under reduced pressure to obtain a plant extract;
weighing 15 parts of deionized water, 6 parts of isononyl isononanoate, 5 parts of butanediol, 13 parts of glycerol, 7 parts of cetearyl alcohol, 5 parts of triglyceride, 14 parts of neohesperidin dihydrochalcone extract, 5.5 parts of polydimethylsiloxane, 5 parts of xanthan gum, 0.4 part of sodium hyaluronate, 3 parts of plant extract, 4 parts of hydrogenated lecithin and 7 parts of polyethylene glycol, uniformly stirring butanediol and xanthan gum, mixing the sodium hyaluronate with the deionized water, adding a mixture of propylene glycol and the xanthan gum, uniformly stirring at 48 ℃, adding the plant extract, continuously and uniformly stirring to prepare an aqueous phase base agent, mixing the glycerol, the cetearyl alcohol, the triglyceride, the isononyl isononanoate, the polydimethylsiloxane and the hydrogenated lecithin, heating to 33 ℃ and uniformly stirring to prepare an oil phase base agent, mixing the aqueous phase base agent and the oil phase base agent, stirring for 25min, and then adding the neohesperidin dihydrochalcone extract at the temperature of 58 ℃, continuously stirring until the mixture is uniform and has no obvious granular sensation, cooling to 35 ℃, preserving the temperature for 35min, and naturally cooling to obtain the efficient anti-aging moisturizing, soothing, repairing and anti-wrinkle cream.
Although embodiments of the present invention have been shown and described, it will be appreciated by those skilled in the art that changes, modifications, substitutions and alterations can be made in these embodiments without departing from the principles and spirit of the invention, the scope of which is defined in the appended claims and their equivalents.
Claims (8)
1. A high-efficiency anti-aging moisturizing soothing repairing anti-wrinkle cream containing a neohesperidin dihydrochalcone extract component comprises deionized water, isononyl isononanoate, butanediol, glycerol, cetearyl alcohol, triglyceride, a neohesperidin dihydrochalcone extract, polydimethylsiloxane, xanthan gum, sodium hyaluronate, a plant extract, hydrogenated lecithin and polyethylene glycol, wherein the weight ratio of each component is as follows: 12-15 parts of deionized water, 4-6 parts of isononyl isononanoate, 4-5 parts of butanediol, 12-13 parts of glycerol, 4-7 parts of cetearyl alcohol, 3.5-5 parts of triglyceride, 12-14 parts of neohesperidin dihydrochalcone extract, 4.5-5.5 parts of polydimethylsiloxane, 4-5 parts of xanthan gum, 0.3-0.4 part of sodium hyaluronate, 2-3 parts of plant extract, 3.5-4 parts of hydrogenated lecithin and 5-7 parts of polyethylene glycol.
2. A method for preparing efficient anti-aging moisturizing soothing repairing anti-wrinkle cream containing neohesperidin dihydrochalcone extract comprises the following steps:
s1, uniformly stirring butanediol and xanthan gum, mixing sodium hyaluronate and deionized water, adding a mixture of propanediol and xanthan gum, uniformly stirring at 45-48 ℃, adding a plant extract, and continuously and uniformly stirring to prepare a water-phase base agent;
s2, mixing glycerol, cetostearyl alcohol, triglyceride, isononyl isononanoate, polydimethylsiloxane and hydrogenated lecithin, heating to 20-33 ℃, and uniformly stirring to obtain an oil phase base agent;
s3, mixing the water phase base agent and the oil phase base agent, stirring for 20-25 min, adding the neohesperidin dihydrochalcone extract at 55-58 ℃, continuously stirring until the mixture is uniform and has no obvious granular sensation, cooling to 32-35 ℃, preserving the temperature for 30-35 min, and naturally cooling to obtain the efficient anti-aging moisturizing soothing and repairing anti-wrinkle cream.
3. The cream containing the neohesperidin dihydrochalcone extract component, which is used for efficiently resisting aging, moisturizing, relieving, repairing and resisting wrinkles, according to claim 1, is characterized in that: the neohesperidin dihydrochalcone extract is prepared by mixing sodium citrate, mannitol, trehalose and deionized water, and the weight ratio of each component is as follows: 0.2-0.4 part of sodium citrate, 4-6 parts of mannitol, 0.5-0.69 part of trehalose, 8-11 parts of neohesperidin dihydrochalcone solution and 70-85 parts of deionized water.
4. The cream containing the neohesperidin dihydrochalcone extract component, which is used for efficiently resisting aging, moisturizing, relieving, repairing and resisting wrinkles, according to claim 3, is characterized in that: the preparation method of the neohesperidin dihydrochalcone extract comprises the following steps:
s11, adding water to dissolve sodium citrate, mannitol and trehalose, adjusting the pH value to 6.9-7.1 to obtain an extraction solution, heating the extraction solution to 73-75 ℃, keeping the temperature for 35min, cooling the extraction solution, and slowly adding a neohesperidin dihydrochalcone solution into the extraction solution when the temperature of the extraction solution is reduced to be below 55 ℃ to obtain a neohesperidin dihydrochalcone-containing liquid;
s12, cooling the liquid containing the neohesperidin dihydrochalcone to-8 ℃ within 68-73 min to obtain a first product, cooling the first product to-55-58 ℃ again and preserving heat for 85-100 min to obtain a second product, heating the second product to-45-48 ℃ first and preserving heat for 65-70 min at the heat preservation pressure of 32-34 bar, then heating to 13-15 ℃ and preserving heat for 100-120 min at the heat preservation pressure of 32-34 bar to obtain a third product, heating the third product to 28-32 ℃ and preserving heat for 38-44 min at the heat preservation pressure of 32-34 bar, and finally heating to 42-46 ℃ and preserving heat for 85-100 min at the heat preservation pressure of 10-15 bar to obtain the neohesperidin dihydrochalcone extract.
5. The cream containing the neohesperidin dihydrochalcone extract component, which is used for efficiently resisting aging, moisturizing, relieving, repairing and resisting wrinkles, according to claim 4, is characterized in that: in the step S11, when the neohesperidin dihydrochalcone solution is slowly added to the extraction solution, uniform stirring is required to avoid foaming.
6. The cream containing the neohesperidin dihydrochalcone extract component, which is used for efficiently resisting aging, moisturizing, relieving, repairing and resisting wrinkles, according to claim 1, is characterized in that: the plant extract is prepared by mixing ginseng, dendrobium huoshanense, polygonum multiflorum, gentian, ethanol and deionized water, and the components are as follows by weight ratio: 0.08-0.23 part of ginseng, 0.12-0.25 part of dendrobium huoshanense, 2.5-3.5 parts of polygonum multiflorum, 2-3 parts of felwort, 10-15 parts of ethanol and 20-25 parts of deionized water.
7. The cream containing the neohesperidin dihydrochalcone extract component, which is used for efficiently resisting aging, moisturizing, relieving, repairing and resisting wrinkles, according to claim 6, is characterized in that: the preparation method of the plant extract comprises the following steps:
s21, putting the ginseng, the dendrobium huoshanense, the polygonum multiflorum and the gentian into deionized water, heating to 75-78 ℃, keeping the temperature for 5-8 min, taking out, washing with the deionized water, and cooling;
s22, feeding the cooled ginseng, dendrobium huoshanense, polygonum multiflorum and gentian into a grinder for grinding, feeding the ground ginseng, dendrobium huoshanense, polygonum multiflorum and gentian into ethanol, heating to 25-30 ℃, preserving heat for 1.5-2 h, filtering, collecting filtrate, and concentrating under reduced pressure to obtain the plant extract.
8. The cream containing the neohesperidin dihydrochalcone extract component, which is used for efficiently resisting aging, moisturizing, relieving, repairing and resisting wrinkles, according to claim 7, is characterized in that: the particle size of the ginseng, the dendrobium huoshanense, the polygonum multiflorum and the gentian which are crushed in the S22 is 30-35 mu m.
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Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110022850A (en) * | 2016-11-29 | 2019-07-16 | 莱雅公司 | Composition comprising truffle extract and neohesperidin dihydrochalcone |
| CN114632018A (en) * | 2020-12-15 | 2022-06-17 | 爱敬产业株式会社 | Skin external composition containing neohesperidin dihydrochalcone |
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Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110022850A (en) * | 2016-11-29 | 2019-07-16 | 莱雅公司 | Composition comprising truffle extract and neohesperidin dihydrochalcone |
| CN114632018A (en) * | 2020-12-15 | 2022-06-17 | 爱敬产业株式会社 | Skin external composition containing neohesperidin dihydrochalcone |
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| 王建新: "《化妆品植物原料大全》", vol. 1, 中国纺织出版社, pages: 130 - 131 * |
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