CN115003156A - 冷冻细胞聚集体的方法 - Google Patents

冷冻细胞聚集体的方法 Download PDF

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CN115003156A
CN115003156A CN202080093132.7A CN202080093132A CN115003156A CN 115003156 A CN115003156 A CN 115003156A CN 202080093132 A CN202080093132 A CN 202080093132A CN 115003156 A CN115003156 A CN 115003156A
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cells
cell
cell aggregates
composition
dopamine
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中川隆
田中一成
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Sumitomo Pharma Co Ltd
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Sumitomo Pharmaceuticals Co Ltd
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    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N1/00—Preservation of bodies of humans or animals, or parts thereof
    • A01N1/10—Preservation of living parts
    • A01N1/12—Chemical aspects of preservation
    • A01N1/122—Preservation or perfusion media
    • A01N1/125—Freeze protecting agents, e.g. cryoprotectants or osmolarity regulators
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N1/00—Preservation of bodies of humans or animals, or parts thereof
    • A01N1/10—Preservation of living parts
    • A01N1/16—Physical preservation processes
    • A01N1/162—Temperature processes, e.g. following predefined temperature changes over time
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/30—Nerves; Brain; Eyes; Corneal cells; Cerebrospinal fluid; Neuronal stem cells; Neuronal precursor cells; Glial cells; Oligodendrocytes; Schwann cells; Astroglia; Astrocytes; Choroid plexus; Spinal cord tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
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    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
    • A61L27/3804—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by specific cells or progenitors thereof, e.g. fibroblasts, connective tissue cells, kidney cells
    • A61L27/3834—Cells able to produce different cell types, e.g. hematopoietic stem cells, mesenchymal stem cells, marrow stromal cells, embryonic stem cells
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    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0607—Non-embryonic pluripotent stem cells, e.g. MASC
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    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0618—Cells of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • C12N2501/10—Growth factors
    • C12N2501/13—Nerve growth factor [NGF]; Brain-derived neurotrophic factor [BDNF]; Cilliary neurotrophic factor [CNTF]; Glial-derived neurotrophic factor [GDNF]; Neurotrophins [NT]; Neuregulins
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    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/70—Enzymes
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    • C12N2506/00—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells
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    • C12N2533/00—Supports or coatings for cell culture, characterised by material
    • C12N2533/90—Substrates of biological origin, e.g. extracellular matrix, decellularised tissue

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  • Oral & Maxillofacial Surgery (AREA)
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  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
CN202080093132.7A 2019-11-20 2020-11-19 冷冻细胞聚集体的方法 Pending CN115003156A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2019209931 2019-11-20
JP2019-209931 2019-11-20
PCT/JP2020/043276 WO2021100830A1 (ja) 2019-11-20 2020-11-19 細胞凝集体の凍結方法

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CN115003156A true CN115003156A (zh) 2022-09-02

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US (1) US20220408717A1 (https=)
EP (1) EP4063495A4 (https=)
JP (1) JP7702604B2 (https=)
CN (1) CN115003156A (https=)
CA (1) CA3162273A1 (https=)
WO (1) WO2021100830A1 (https=)

Citations (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20060269908A1 (en) * 2005-05-31 2006-11-30 The University Of Washington Cryopreservation of primate embryonic stem cells
CN101070534A (zh) * 2007-05-11 2007-11-14 大连理工大学 一种冷冻保存神经干细胞的方法
WO2008120832A1 (en) * 2007-03-30 2008-10-09 Industry-Academic Cooperation Foundation, Yonsei University Human neural stem cell secreting a smac, preparation method and use thereof
CN102317445A (zh) * 2009-02-19 2012-01-11 纳托林两合公司 细胞、人工细胞构建体或三维复合组织装配体的冷冻保存方法
CN106659148A (zh) * 2014-05-12 2017-05-10 鲁斯特生物股份有限公司 即用打印细胞和集成装置
CN107996559A (zh) * 2018-01-03 2018-05-08 吉林省拓华生物科技有限公司 一种神经干细胞冻存液及其使用方法
CN108293979A (zh) * 2018-03-07 2018-07-20 山东国源人类遗传资源库管理有限公司 一种神经干细胞球玻璃化冻存/复苏方法及冻存装置
JP2019006695A (ja) * 2017-06-22 2019-01-17 学校法人明治大学 生体試料保存容器
US20190046583A1 (en) * 2016-02-11 2019-02-14 Johns Hopkins Technology Ventures Compositions and methods for neuralgenesis
WO2019160148A1 (ja) * 2018-02-19 2019-08-22 大日本住友製薬株式会社 細胞凝集体、細胞凝集体の混合物及びそれらの製造方法

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US6280718B1 (en) 1999-11-08 2001-08-28 Wisconsin Alumni Reasearch Foundation Hematopoietic differentiation of human pluripotent embryonic stem cells
WO2002101057A1 (fr) 2001-06-08 2002-12-19 Dnavec Research Inc. Transfert genique dans des cellules souches embryonnaires de primate a l'aide d'un virus de l'immunodeficience simienne de pseudo type vsv-g utilise comme vecteur
JP2009209930A (ja) * 2008-02-08 2009-09-17 Sanwa Seiki Co Ltd エアコンプレッサ
JPWO2009148170A1 (ja) 2008-06-06 2011-11-04 独立行政法人理化学研究所 幹細胞の培養方法
JP6220108B2 (ja) * 2011-04-04 2017-10-25 株式会社バイオベルデ 多能性幹細胞その他の分散浮遊可能な細胞用の凍結保存液および凍結保存法
JP6210881B2 (ja) 2011-10-31 2017-10-11 国立研究開発法人理化学研究所 幹細胞の培養方法
JP6012164B2 (ja) * 2011-11-25 2016-10-25 住友化学株式会社 多能性幹細胞由来の組織の凍結保存方法
AU2014316100B2 (en) 2013-09-05 2020-11-05 Eisai R&D Management Co., Ltd. New method for inducing dopamine-producing neural precursor cells
ES2732730T3 (es) 2013-11-22 2019-11-25 Riken Método para producir telencéfalo o tejido progenitor del mismo
CA2956130C (en) 2014-07-25 2023-09-26 Riken Method for producing adenohypophysis or precursor tissue thereof
US10781420B2 (en) 2014-09-08 2020-09-22 Riken Method for producing cerebellar progenitor tissue
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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20060269908A1 (en) * 2005-05-31 2006-11-30 The University Of Washington Cryopreservation of primate embryonic stem cells
WO2008120832A1 (en) * 2007-03-30 2008-10-09 Industry-Academic Cooperation Foundation, Yonsei University Human neural stem cell secreting a smac, preparation method and use thereof
CN101070534A (zh) * 2007-05-11 2007-11-14 大连理工大学 一种冷冻保存神经干细胞的方法
CN102317445A (zh) * 2009-02-19 2012-01-11 纳托林两合公司 细胞、人工细胞构建体或三维复合组织装配体的冷冻保存方法
CN106659148A (zh) * 2014-05-12 2017-05-10 鲁斯特生物股份有限公司 即用打印细胞和集成装置
US20190046583A1 (en) * 2016-02-11 2019-02-14 Johns Hopkins Technology Ventures Compositions and methods for neuralgenesis
JP2019006695A (ja) * 2017-06-22 2019-01-17 学校法人明治大学 生体試料保存容器
CN107996559A (zh) * 2018-01-03 2018-05-08 吉林省拓华生物科技有限公司 一种神经干细胞冻存液及其使用方法
WO2019160148A1 (ja) * 2018-02-19 2019-08-22 大日本住友製薬株式会社 細胞凝集体、細胞凝集体の混合物及びそれらの製造方法
CN108293979A (zh) * 2018-03-07 2018-07-20 山东国源人类遗传资源库管理有限公司 一种神经干细胞球玻璃化冻存/复苏方法及冻存装置

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张勇主编: "《生物样本库建设与实践》", 31 December 2013, 广州：中山大学出版社, pages: 105 - 106 *
马学虎等: ""不同直径神经干细胞球慢速低温冻存的研究"", vol. 28, no. 6, pages 910 - 915 *

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JPWO2021100830A1 (https=) 2021-05-27
CA3162273A1 (en) 2021-05-27
WO2021100830A1 (ja) 2021-05-27
JP7702604B2 (ja) 2025-07-04
EP4063495A1 (en) 2022-09-28
US20220408717A1 (en) 2022-12-29
EP4063495A4 (en) 2023-12-27

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